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Drug Development Targeting the Glycogen Synthase Kinase-3β(GSK-3β)-Mediated Signal Transduction Pathway：The Role of GSK-3β in the Maintenance of Steady-State Levels of Insulin Receptor Signaling Molecules and Nav1.7 Sodium Channel in Adrenal Chromaffin Cells
Takayuki Nemoto, Toshihiko Yanagita, Tasuku Kanai, Akihiko Wada
Department of Pharmacology, Miyazaki Medical College, University of Miyazaki
Journal of Pharmacological Sciences 109 (2) 157-161, 2009.
Department of Pharmacology, Miyazaki Medical College, University of Miyazaki
Journal of Pharmacological Sciences 109 (2) 157-161, 2009.
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Drug Development Targeting the Glycogen Synthase Kinase-3β(GSK-3β)-Mediated Signal Transduction Pathway： Role of GSK-3β in Myocardial Protection Against Ischemia/Reperfusion Injury
Tetsuji Miura, Masahiro Nishihara, Takayuki Miki
Second Department of Internal Medicine, Sapporo Medical University, School of Medicine
Journal of Pharmacological Sciences 109 (2) 162-167, 2009.
Second Department of Internal Medicine, Sapporo Medical University, School of Medicine
Journal of Pharmacological Sciences 109 (2) 162-167, 2009.
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Drug Development Targeting the Glycogen Synthase Kinase-3β(GSK-3β)-Mediated Signal Transduction Pathway： Targeting the Wnt Pathway and Transplantation Therapy as Strategies for Retinal Repair
Fumitaka Osakada, Masayo Takahashi
Laboratory for Retinal Regeneration, Center for Developmental Biology, RIKEN
Journal of Pharmacological Sciences 109 (2) 168-173, 2009.
Laboratory for Retinal Regeneration, Center for Developmental Biology, RIKEN
Journal of Pharmacological Sciences 109 (2) 168-173, 2009.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
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Drug Development Targeting the Glycogen Synthase Kinase-3β(GSK-3β)-Mediated Signal Transduction Pathway： Role of GSK-3β in Adult Brain
Akihiko Takashima
Laboratory for Alzheimer's Disease, RIKEN Brain Science Institute
Journal of Pharmacological Sciences 109 (2) 174-178, 2009.
Laboratory for Alzheimer's Disease, RIKEN Brain Science Institute
Journal of Pharmacological Sciences 109 (2) 174-178, 2009.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
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Drug Development Targeting the Glycogen Synthase Kinase-3β(GSK-3β)-Mediated Signal Transduction Pathway: Inhibitors of the Wnt/β-Catenin Signaling Pathway as Novel Anticancer Drugs
Fumi Takahashi-Yanaga, Toshiyuki Sasaguri
Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu University
Journal of Pharmacological Sciences 109 (2) 179-183, 2009.
Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu University
Journal of Pharmacological Sciences 109 (2) 179-183, 2009.
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FKBP12 Depletion Leads to Loss of Sarcoplasmic Reticulum Ca2+ Stores in Rat Vas Deferens
Christianne B.V. Scaramello1, Humberto Muzi-Filho1, Gisele Zapata-Sudo2, Roberto T. Sudo3, Valeria do M.N. Cunha1
1 Laboratorio de Farmacologia Bioquimica de Tecidos Musculares, 2 Laboratorio de Farmacologia Cardiovascular and, 3 Laboratorio de Excitacao-Contracao Muscular, Instituto de Ciencias Biomedicas, Universidade Federal do Rio de Janeiro
Journal of Pharmacological Sciences 109 (2) 185-192, 2009.
1 Laboratorio de Farmacologia Bioquimica de Tecidos Musculares, 2 Laboratorio de Farmacologia Cardiovascular and, 3 Laboratorio de Excitacao-Contracao Muscular, Instituto de Ciencias Biomedicas, Universidade Federal do Rio de Janeiro
Journal of Pharmacological Sciences 109 (2) 185-192, 2009.
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Wortmannin Inhibits the Increase in Myofilament Ca2+ Sensitivity Induced by Cross-Talk of Endothelin-1 With Norepinephrine in Canine Ventricular Myocardium
Li Chu1, 2, Ikuo Norota1, Kuniaki Ishii1, Masao Endoh1
1 Department of Cardiovascular Pharmacology, Yamagata University School of Medicine, 2 Department of Pharmacology, Hebei Medical University
Journal of Pharmacological Sciences 109 (2) 193-202, 2009.
1 Department of Cardiovascular Pharmacology, Yamagata University School of Medicine, 2 Department of Pharmacology, Hebei Medical University
Journal of Pharmacological Sciences 109 (2) 193-202, 2009.
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Improvement of Motor Nerve Conduction Velocity in Diabetic Rats Requires Normalization of the Polyol Pathway Metabolites Flux
Takafumi Matsumoto1, Yoshiyuki Ono2, Masuo Kurono3, Akemi Kuromiya4, Keiji Nakamura5, Vera Bril6
1 Pharmacology Research Laboratories, 4 Genomic Science Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 2 International Business Management, Dainippon Sumitomo Pharma Co., Ltd., 3 Chemistry Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 5 Analytical Chemistry Center Nichiei Sangyo Co., Ltd., 6 Department of Medicine, University of Toronto EN11-209, Toronto General Hospital
Journal of Pharmacological Sciences 109 (2) 203-210, 2009.
1 Pharmacology Research Laboratories, 4 Genomic Science Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 2 International Business Management, Dainippon Sumitomo Pharma Co., Ltd., 3 Chemistry Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 5 Analytical Chemistry Center Nichiei Sangyo Co., Ltd., 6 Department of Medicine, University of Toronto EN11-209, Toronto General Hospital
Journal of Pharmacological Sciences 109 (2) 203-210, 2009.
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The Efficacy and Mechanism Action of RvCSd, a New Herbal Agent, on Immune Suppression and Cartilage Protection in a Mouse Model of Rheumatoid Arthritis
Jae-Dong Lee1, Jeong-Eun Huh2, Yong-Hyeon Baek3, Ku-Chil Cho1, Do-Young Choi1, Dong-Suk Park3
1 Department of Acupuncture & Moxibustion, College of Oriental Medicine, KyungHee University, 2 Oriental Medicine Research Center for Bone and Joint Disease, KyungHee University, 3 Department of Acupuncture & Moxibustion, East-West Neo Medical Center, KyungHee University
Journal of Pharmacological Sciences 109 (2) 211-221, 2009.
1 Department of Acupuncture & Moxibustion, College of Oriental Medicine, KyungHee University, 2 Oriental Medicine Research Center for Bone and Joint Disease, KyungHee University, 3 Department of Acupuncture & Moxibustion, East-West Neo Medical Center, KyungHee University
Journal of Pharmacological Sciences 109 (2) 211-221, 2009.
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KR-31761, a Novel K+ATP-Channel Opener, Exerts Cardioprotective Effects by Opening Both Mitochondrial K+ATP and Sarcolemmal K+ATP Channels in Rat Models of Ischemia/Reperfusion-Induced Heart Injury
Min-Kyu Yang1, Sung-Hun Lee1, Ho-Won Seo2, Kyu-Yang Yi2, Sung-Eun Yoo2, Byung-Ho Lee2, Hun-Jong Chung3, Hyung-Sik Won4, Chang-Soo Lee1, Suk-Hyung Kwon5, Wahn-Soo Choi6, Hwa-Sup Shin1
1 Department of Applied Biochemistry, 4 Department of Biotechnology, Division of Life Science, College of Biomedical and Health Science, Konkuk University, 2 Medical Science Division, Korea Research Institute of Chemical Technology, 3 Pediatric Department, Chungju Hospital, Konkuk Medical School, Konkuk University, 5 Rexgene Biotech Co., Ltd., 6 Department of Immunology, College of Medicine, Konkuk University
Journal of Pharmacological Sciences 109 (2) 222-232, 2009.
1 Department of Applied Biochemistry, 4 Department of Biotechnology, Division of Life Science, College of Biomedical and Health Science, Konkuk University, 2 Medical Science Division, Korea Research Institute of Chemical Technology, 3 Pediatric Department, Chungju Hospital, Konkuk Medical School, Konkuk University, 5 Rexgene Biotech Co., Ltd., 6 Department of Immunology, College of Medicine, Konkuk University
Journal of Pharmacological Sciences 109 (2) 222-232, 2009.
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Capsaicin-Induced Glutamate Release Is Implicated in Nociceptive Processing Through Activation of Ionotropic Glutamate Receptors and Group I Metabotropic Glutamate Receptor in Primary Afferent Fibers
You-Hong Jin1, Fumiko Yamaki2, Motohide Takemura3, Yuichi Koike4, Akira Furuyama5, Norifumi Yonehara2
1 Departments of Pharmacology Osaka University Graduate School of Dentistry, 2 Divisions of Phamacology Ohu University School of Pharmaceutical Science, 3 Oral Anatomy and Neurobiology, Osaka University Graduate School of Dentistry Divisions of Pharmacology, 4 Drug Metabolism and Clinical Pharmacokinetics, Ohu University School of Pharmaceutical Science, Koriyama, 5 Department of Oral Physiology, Ohu University School of Dentistry
Journal of Pharmacological Sciences 109 (2) 233-241, 2009.
1 Departments of Pharmacology Osaka University Graduate School of Dentistry, 2 Divisions of Phamacology Ohu University School of Pharmaceutical Science, 3 Oral Anatomy and Neurobiology, Osaka University Graduate School of Dentistry Divisions of Pharmacology, 4 Drug Metabolism and Clinical Pharmacokinetics, Ohu University School of Pharmaceutical Science, Koriyama, 5 Department of Oral Physiology, Ohu University School of Dentistry
Journal of Pharmacological Sciences 109 (2) 233-241, 2009.
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Induction of Multiple Drug Transporters by Efavirenz
Johanna Weiss1, Melanie Herzog1, Sonja Konig1, Caroline Henrike Storch1, Nahal Ketabi-Kiyanvash1, Walter Emil Haefeli1
1 Department of Internal Medicine VI, Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg
Journal of Pharmacological Sciences 109 (2) 242-250, 2009.
1 Department of Internal Medicine VI, Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg
Journal of Pharmacological Sciences 109 (2) 242-250, 2009.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
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Glimepiride Treatment Upon Reperfusion Limits Infarct Size via the Phosphatidylinositol 3-Kinase/Akt Pathway in Rabbit Hearts
Hirofumi Nishida1, 2, Toshiaki Sato1, Momoko Nomura1, 2, Masaru Miyazaki2, Haruaki Nakaya1
1 Department of Pharmacology, Chiba University Graduate School of Medicine, 2 Department of General Surgery, Chiba University Graduate School of Medicine
Journal of Pharmacological Sciences 109 (2) 251-256, 2009.
1 Department of Pharmacology, Chiba University Graduate School of Medicine, 2 Department of General Surgery, Chiba University Graduate School of Medicine
Journal of Pharmacological Sciences 109 (2) 251-256, 2009.
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Quercetin Glucuronide Inhibits Cell Migration and Proliferation by Platelet-Derived Growth Factor in Vascular Smooth Muscle Cells
Keisuke Ishizawa1, Yuki Izawa-Ishizawa1, Sachiyo Ohnishi2, Yuki Motobayashi1, Kazuyoshi Kawazoe2, Shuichi Hamano3, Koichiro Tsuchiya4, Shuhei Tomita1, Kazuo Minakuchi2, Toshiaki Tamaki1
1 Department of Pharmacology The University of Tokushima Graduate School, 2 Department of Clinical Pharmacy The University of Tokushima Graduate School, 3 Department of Pathological Science and Technology, The University of Tokushima Graduate School, 4 Department of Medical Pharmacology, The Institute of Health Bioscience, The University of Tokushima Graduate School
Journal of Pharmacological Sciences 109 (2) 257-264, 2009.
1 Department of Pharmacology The University of Tokushima Graduate School, 2 Department of Clinical Pharmacy The University of Tokushima Graduate School, 3 Department of Pathological Science and Technology, The University of Tokushima Graduate School, 4 Department of Medical Pharmacology, The Institute of Health Bioscience, The University of Tokushima Graduate School
Journal of Pharmacological Sciences 109 (2) 257-264, 2009.
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Role of Glucocorticoid Receptor in the Regulation of Cellular Sensitivity to Irinotecan Hydrochloride
Takanori Akagi1, Tatsuo Fukagawa2, Yuki Kage1, Hideto To3, Naoya Matsunaga4, Satoru Koyanagi4, Akiko Uchida1, Asuka Fujii1, Hideo Iba5, Toshimichi Ikemura2, Hironori Aramaki6, Shun Higuchi1, Shigehiro Ohdo4
1 Departments of Clinical Pharmacokinetics Graduate School, Kyushu University, 4 Depertment of Clinical Pharmaceutics, Division of Pharmaceutical Sciences, Graduate School, Kyushu University, 2 National Institute of Genetics and The Graduate University for Advanced Studies, 3 Department of Hospital Pharmacy, Nagasaki University Hospital of Medicine and Dentistry, 5 Division of Host-Parasite Interaction, Department of Microbiology and Immunology, Institute of Medical Science, The University of Tokyo, 6 Department of Molecular Biology, Daiichi College of Pharmaceutical Sciences
Journal of Pharmacological Sciences 109 (2) 265-274, 2009.
1 Departments of Clinical Pharmacokinetics Graduate School, Kyushu University, 4 Depertment of Clinical Pharmaceutics, Division of Pharmaceutical Sciences, Graduate School, Kyushu University, 2 National Institute of Genetics and The Graduate University for Advanced Studies, 3 Department of Hospital Pharmacy, Nagasaki University Hospital of Medicine and Dentistry, 5 Division of Host-Parasite Interaction, Department of Microbiology and Immunology, Institute of Medical Science, The University of Tokyo, 6 Department of Molecular Biology, Daiichi College of Pharmaceutical Sciences
Journal of Pharmacological Sciences 109 (2) 265-274, 2009.
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Long-Term Angiotensin II Blockade May Improve Not Only Hyperglycemia but Also Age-Associated Cardiac Fibrosis
Denan Jin1, Shinji Takai1, Tetsuya Sugiyama2, Tetsuya Hayashi3, Masanori Fukumoto2, Hidehiro Oku2, Yasushi Kitaura3, Tsunehiko Ikeda2, Mizuo Miyazaki1
1 Departments of Pharmacology Osaka Medical College, 2 Ophthalmology, Osaka Medical College, 3 Third Department of Medicine, Osaka Medical College
Journal of Pharmacological Sciences 109 (2) 275-284, 2009.
1 Departments of Pharmacology Osaka Medical College, 2 Ophthalmology, Osaka Medical College, 3 Third Department of Medicine, Osaka Medical College
Journal of Pharmacological Sciences 109 (2) 275-284, 2009.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
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Leukotriene D4 Stimulates the Migration but Not Proliferation of Endothelial Cells Mediated by the Cysteinyl Leukotriene CysLT1 Receptor via the Extracellular Signal-Regulated Kinase Pathway
Yu-Mei Yuan1,2, San-Hua Fang1, Xiao-Dong Qian2, Li-Ying Liu1, Li-Hua Xu1, Wen-Zhen Shi1, Li-Hui Zhang3, Yun-Bi Lu1, Wei-Ping Zhang1, Er-Qing Wei1
1 Department of Pharmacology, School of Medicine, Zhejiang University, 2 Department of Pharmacy, Huzhou Central Hospital, 3 Department of Pharmacology, School of Basic Medicine, Hangzhou Normal University
Journal of Pharmacological Sciences 109 (2) 285-292, 2009.
1 Department of Pharmacology, School of Medicine, Zhejiang University, 2 Department of Pharmacy, Huzhou Central Hospital, 3 Department of Pharmacology, School of Basic Medicine, Hangzhou Normal University
Journal of Pharmacological Sciences 109 (2) 285-292, 2009.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
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Swelling-Activated Cl- Current in Isolated Rabbit Articular Chondrocytes： Inhibition by Arachidonic Acid
Eiji Isoya1, 2, Futoshi Toyoda2, Shinji Imai1, Noriaki Okumura1, 2, Kousuke Kumagai1, 2, Mariko Omatsu-Kanbe2, Mitsuhiko Kubo1, Hiroshi Matsuura2, Yoshitaka Matsusue1
1 Department of Orthopaedic Surgery, Shiga University of Medical Science, 2 Department of Physiology, Shiga University of Medical Science
Journal of Pharmacological Sciences 109 (2) 293-304, 2009.
1 Department of Orthopaedic Surgery, Shiga University of Medical Science, 2 Department of Physiology, Shiga University of Medical Science
Journal of Pharmacological Sciences 109 (2) 293-304, 2009.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
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Methylglyoxal Inhibits Smooth Muscle Contraction in Isolated Blood Vessels
Masashi Mukohda1, Hideyuki Yamawaki1, Hidemi Nomura1, Muneyoshi Okada1, Yukio Hara1
1 Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Kitasato University
Journal of Pharmacological Sciences 109 (2) 305-310, 2009.
1 Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Kitasato University
Journal of Pharmacological Sciences 109 (2) 305-310, 2009.
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The Protective Effect of a Newly Developed Molecular Chaperone-Inducer Against Mouse Ischemic Acute Kidney Injury
Worapat Prachasilchai1, Hiroko Sonoda1, Naoko Yokota-Ikeda2, Katsuaki Ito1, Takashi Kudo3, Kazunori Imaizumi4, Masahiro Ikeda1
1 Department of Veterinary Pharmacology, Faculty of Agriculture, University of Miyazaki, 2 Nephrology Division, Miyazaki Prefectural Mivazaki Hospital, 3 Psychiatry, Department of Integrated Medicine, Division of Internal Medicine, Osaka University Graduate School of Medicine, 4 Division of Molecular and Cellular Biology, Department of Anatomy, Faculty of Medicine, University of Miyazaki
Journal of Pharmacological Sciences 109 (2) 311-314, 2009.
1 Department of Veterinary Pharmacology, Faculty of Agriculture, University of Miyazaki, 2 Nephrology Division, Miyazaki Prefectural Mivazaki Hospital, 3 Psychiatry, Department of Integrated Medicine, Division of Internal Medicine, Osaka University Graduate School of Medicine, 4 Division of Molecular and Cellular Biology, Department of Anatomy, Faculty of Medicine, University of Miyazaki
Journal of Pharmacological Sciences 109 (2) 311-314, 2009.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
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The New Salicylate Derivative UR-1505 Modulates the Th2/Humoral Response in a Dextran Sodium Sulphate Model of Colitis That Resembles Ulcerative Colitis
Elvira Bailon1, Juan Roman2, Isabel Ramis2, Pedro Michelena2, Dolors Balsa2, Manuel Merlos2, Antonio Zarzuelo1, Julio Galvez1, Monica Comalada1
1 Centro de Investigation Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBEREHD), Department of Pharmacology, School of Pharmacy, University of Granada, Campus Universitario 'La Cartuja' s/n, 2 Pharmacology & Toxicology, Palau Pharma S.A
Journal of Pharmacological Sciences 109 (2) 315-318, 2009.
1 Centro de Investigation Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBEREHD), Department of Pharmacology, School of Pharmacy, University of Granada, Campus Universitario 'La Cartuja' s/n, 2 Pharmacology & Toxicology, Palau Pharma S.A
Journal of Pharmacological Sciences 109 (2) 315-318, 2009.
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Expression of mRNA for 5-HT2 Receptors and Proteins Related to Inactivation of 5-HT in Mouse Osteoblasts
Takao Hirai, Kohji Tokumo, Daijyu Tsuchiya, Hiroaki Nishio
Department of Molecular Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University
Journal of Pharmacological Sciences 109 (2) 319-323, 2009.
Department of Molecular Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University
Journal of Pharmacological Sciences 109 (2) 319-323, 2009.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
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