Journal of Pharmacological Sciences 101巻 suppl号

前の号 次の号

発行元: 日本薬理学会

ISSN: 1347-8613

ISSN（オンライン）: 1347-8648

前雑誌: Japanese Journal of Pharmacology

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The Role of Serotonin in Behaviour: from the Genesis of an Experimental Approach to Constitutive Activity

John A. Harvey
Drexel University College of Medicine, Philadelphia, PA 19102-1192, USA
Journal of Pharmacological Sciences 101 (suppl) 2-2, 2006.

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Examining the Function of Serotonin in Brain: from Depression to Ecstasy

A. R. Green
AstraZeneca R&D Charnwood, Loughborough LE11 5RH, UK
Journal of Pharmacological Sciences 101 (suppl) 4-4, 2006.

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5-HT7 Receptors as a Pharmacological Target in Neuropsychiatric Disorders

P. B. Hedlund, J. G. Sutcliffe
Department of Molecular Biology, the Scripps Research Institute
Journal of Pharmacological Sciences 101 (suppl) 6-6, 2006.

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5-HT7 and 5-ht5A Receptors: Their Emerging Roles in Brain Function and Available Pharmacological Tools

D. R. Thomas
GlaxoSmithKline
Journal of Pharmacological Sciences 101 (suppl) 7-7, 2006.

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Recent advances in the field of 5-HT7 receptor agents with 1-arylpiperazine structure

M. Leopoldo, E. Lacivita, P. De Giorgio, N. A. Colabufo, M. Contino, M. Niso, F. Berardi, R. Perrone
University degli Studi di Bari- Dipartimento Farmaco-Chimico
Journal of Pharmacological Sciences 101 (suppl) 8-8, 2006.

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The Role of Central 5-HT7 in the Control of Micturition and the Cardiovascular System

A. G. Ramage
Department of Pharmacology, UCL, London U. K
Journal of Pharmacological Sciences 101 (suppl) 9-9, 2006.

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Regulation of 5-HTIA Receptor Function in BDNF Deficient Mice

J. G. Hensler, L. M. Monteggia
Institutions: University of Texas Health Science Center-San Antonio, Texas; University of Texas Southwestern Medical Center, Dallas, Texas.
Journal of Pharmacological Sciences 101 (suppl) 10-10, 2006.

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Reciprocal Interaction of 5-HT and Neuronal Activity in Regulation of CRE-dependent Gene Expression

MA Mahgoub, Y Sara, M Adachi, ET Kavalali, LM Monteggia
The University of Texas Southwestern Medical Center
Journal of Pharmacological Sciences 101 (suppl) 11-11, 2006.

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SERTain Regulation of Serotonin Neurotransmission by BDNF

L. C. DAWS, J. G. HENSLER
Departments of Physiology and Pharmacology University of Texas Health Science Center at San Antonio
Journal of Pharmacological Sciences 101 (suppl) 12-12, 2006.

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Exploring Functional Interactions between SERT and BDNF in the Mediation of Emotional Behavior Using Mutant Mice

A Holmes
Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism
Journal of Pharmacological Sciences 101 (suppl) 13-13, 2006.

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Serotonergic drugs for the treatment of obesity

GA Bray
Pennington Biomedical Research Center
Journal of Pharmacological Sciences 101 (suppl) 14-14, 2006.

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Agonist Diversity in 5-HT2C Receptor-mediated Weight Control

A. Hayashi, M. Suzuki, M. Sasamata, K. Miyata
Institute for Drug Discovery Research, Astellas Pharma Inc.
Journal of Pharmacological Sciences 101 (suppl) 15-15, 2006.

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Promising Novel 5-HT6 Receptor Ligands to Treat Obesity

P. J. Pauwels, A. Fisas, X. Codony, H. Buschmann
Laboratorios Dr. Esteve S. A. , Av. Mare de Deu de Montserrat 221
Journal of Pharmacological Sciences 101 (suppl) 16-16, 2006.

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Assessment of the Potential Efficacy and CNS side-effects of Novel Serotonergic Anti-obesity Agents in Phase 1 Clinical Studies

C. T. Dourish1), E. Boyland2), J. C. G. Halford2), G. R. Dawson', J. P. H. Wilding3)
1)P1vital, Dept. Psychiatry, University of Oxford, Oxford OX3 7JX, 2)School of Psychology, University of Liverpool, L69 7ZA, 3)Dept. Medicine, University Hospital Aintree, Liverpool L9 7AL
Journal of Pharmacological Sciences 101 (suppl) 17-17, 2006.

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Distinct Effects Mediated by Corticotropin-releasing Factor (CRF) Receptor Subtypes May Determine Opposing Coping Styles

R. J. Valentino, M. Waselus, E. J. Van Bockstaele
The Children's Hospital of Philadelphia and Thomas Jefferson University Medical School
Journal of Pharmacological Sciences 101 (suppl) 18-18, 2006.

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Microcircuitry of the Raphe and its Regulation by Stress

S. G. Beck
Children's Hospital of Philadelphia and University of Pennsylvania
Journal of Pharmacological Sciences 101 (suppl) 19-19, 2006.

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Activity of presumed serotonin neurons: Are they all the same?

M. Hajos
Pfizer Global Research & Development
Journal of Pharmacological Sciences 101 (suppl) 20-20, 2006.

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Genetic Mechanisms directing Development of Serotonin-modulated Behaviors

E Deneris
Case Western Reserve University
Journal of Pharmacological Sciences 101 (suppl) 21-21, 2006.

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Cognitive Effects of Psilocybin, the Role of 5HT1 and 5HT2 Receptors in Cognition"

Franz X. Vollenweider(1), Daniel Hell(1), Trevor Robbins(2), Mark A. Geyer(3)
(1)University Hospital of Psychiatry, University of Zurich, (2)Department of Experimental Psychology, University of Cambridge, (3)Department of Psychiatry, University of California San Diego
Journal of Pharmacological Sciences 101 (suppl) 22-22, 2006.

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Neural Substrates Underlying the Modulation of Decision-making and Error Processing by Psilocybin

Martin P Paulus, Franx X Vollenweider
Department of Psychiatry, Laboratory of Biological Dynamics and Theoretical Medicine, University of California San Diego
Journal of Pharmacological Sciences 101 (suppl) 23-23, 2006.

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Effect of Estrogen on Serotonin-1A Receptor-mediated Disruption of Prepulse Inhibition

M. van den Buuse, A. Gogos

Journal of Pharmacological Sciences 101 (suppl) 24-24, 2006.

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Alterations of 5-HTIA and 5-HT2A Receptors and the 5-HT Transporter in Anorexia and Bulimia Nervosa: Results from PET Imaging Studies

WH Kaye1), GK Frank2), A Wagner3), UF Bailer4), CC Meltzer5, 6), C Mathis5), J Prices5)
1)University of Pittsburgh School of Medicine, Department of Psychiatry,, 2)University of California San Diego, Department of Child and Adolescent Psychiatry,, 3)Klinik fur Psychiatrie and Psychotherapie des Kindes- and Jugendalters, Universitatsklinikum,, 4)Medical University of Vienna, Department of General Psychiatry,, 5)University of Pittsburgh School of Medicine, Department of Radiology,, 6)University of Pittsburgh School of Medicine, Department of Neurology
Journal of Pharmacological Sciences 101 (suppl) 25-25, 2006.

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5-HT1 receptors: Pharmacological Targets in the Cardiovascular System, from Migraine to Preeclampsia

A. MaassenVanDenBrink
Department of Pharmacology, Erasmus MC, Rotterdam, The Netherlands
Journal of Pharmacological Sciences 101 (suppl) 26-26, 2006.

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Receptor Mechanisms involved in the Cardiac Sympatho-inhibition Induced by ergotamine

D. Centurion, L. E. Cobos-Puc, A. Sanchez-Lopez, C. M. Villalon.
Depto. de Farmacobiologia, Cinvestav-Coapa, 14330 Mexico D. F. , Mexico.
Journal of Pharmacological Sciences 101 (suppl) 27-27, 2006.

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The Role of 5-HTIB,1D Receptors Mediating a Specific Inhibition on Capsaicin-induced Canine External Carotid Vasodilatation.

Carlos M. Villalon
Dep. de Farmacobiologia, Cinvestav-Coapa, Czda. de los Tenorios 235, Col. Granjas-Coapa, 14330 Mexico D. F. , Mexico
Journal of Pharmacological Sciences 101 (suppl) 28-28, 2006.

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Dual serotonergic regulation of the failing cardiac ventricle: Mechanisms and possible therapeutic consequences

F. O. Levy
Department of Pharmacology, University of Oslo, N-0316 Oslo, Norway Center for Heart Failure Research, Faculty of Medicine, University of Oslo, Oslo, Norway
Journal of Pharmacological Sciences 101 (suppl) 29-29, 2006.

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Mood Disorders and Serotonin-induced Calcium Mobilization

Ichiro Kusumi
Dept. of Psychiatry, Hokkaido Univ. Graduate Sch. of Med.
Journal of Pharmacological Sciences 101 (suppl) 30-30, 2006.

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Trait and State Marker, Serotonin Transporter Gene Expression

S Ueno, T Ohmori*
Department of Community and Psychiatric Nursing, School of Health Sciences, University of Tokushima Department of Psychiatry, Course of Integrated Brain Sciences, Medical Informatics, Institute of Health Biosciences, University of Tokushima Graduate School.
Journal of Pharmacological Sciences 101 (suppl) 31-31, 2006.

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Role of Serotonin in Prediction of Future Rewards -Toward Elucidation of Pathophysiology in Depression-

Yasumasa Okamoto
Department of Psychiatry and Neurosciences, Graduate School of Biomedical Sciences, Hiroshima University
Journal of Pharmacological Sciences 101 (suppl) 32-32, 2006.

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Quantitative Imaging of Serotonin Transporter in Living Human Brain

T. Suhara
Molecular Neuroimaging Group, Molecular Imaging Center, National Institute of Radiological Sciences
Journal of Pharmacological Sciences 101 (suppl) 33-33, 2006.

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Multiple Serotonin Receptor Subtypes Contribute to the Effects of Serotonin in Rat Prefrontal Cortex

Rodrigo Andrade
Wayne State University School of Medicine
Journal of Pharmacological Sciences 101 (suppl) 34-34, 2006.

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Cell-type Specific Effects of Serotonin in Cortex

R. C. Foehring
University of Tennessee
Journal of Pharmacological Sciences 101 (suppl) 35-35, 2006.

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Serotoninergic Modulation of Cortical Neuron Input Selectivity.

W. J. Spain, M. H Higgs
University of Washington and VAPSHCS
Journal of Pharmacological Sciences 101 (suppl) 36-36, 2006.

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Immunomodulatory Actions of Serotonin Enhancing Agents: Friend or Foe?

T. J. Connor
Trinity College Dublin, Ireland
Journal of Pharmacological Sciences 101 (suppl) 37-37, 2006.

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Serotonin as a Modulator of Dendritic Cell Function: a Link to Asthmatic Airway Inflammation?

Marco Idzko
Institutions: Department of Pneumology, University-Hospital Freiburg, Kilianstrasse 5, 79106 Freiburg, Germany
Journal of Pharmacological Sciences 101 (suppl) 38-38, 2006.

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Intracellular Serotonin Signaling: The Modulatory Role of Monoaminylation on G Protein Activity

D. J. Walther
Max-Planck-Institute for Mol. Genetics, Ihnestr. 63-73, Berlin, D-14195 Germany
Journal of Pharmacological Sciences 101 (suppl) 39-39, 2006.

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MATRICS: New Opportunities for Serotonin in Psychiatric Disorders

M. A. Geyer
University of California San Diego
Journal of Pharmacological Sciences 101 (suppl) 40-40, 2006.

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The Galanin 3 Receptor and Serotonin Modulation

Thomas P. Blackburn*, Xiaokui Zhang, C. Alan Kachel, Raymond Catapano Jr., Roderick E. M. Scott
Helicon Therapeutics, Inc.
Journal of Pharmacological Sciences 101 (suppl) 41-41, 2006.

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Potential of 5-HT6 Antagonists for the Treatment of Cognitive Disorders

R. Schreiber, Marie L. Woolley
Sepracor, USA; GSK, UK
Journal of Pharmacological Sciences 101 (suppl) 42-42, 2006.

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ACP-103, a 5-HT2A Receptor Inverse Agonist, as an Adjunctive Therapy in Schizophrenia

Kimberly E. Vanover
ACADIA Pharmaceuticals Inc.
Journal of Pharmacological Sciences 101 (suppl) 43-43, 2006.

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The Role of the C-terminus of the Human 5-HT3A Receptor Subunit

AS Butler, AN Massoura, SA Lindsay, AC Dutton, TJ Dover, AG Hope, NM Barnes
Cellular and Molecular Neuropharmacology Research Group, Department of Pharmacology, Division of Neuroscience, The Medical School, University of Birmingham
Journal of Pharmacological Sciences 101 (suppl) 44-44, 2006.

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Dynamic Behaviour of the 5-HT3 Receptor

E. Guignet, J. Piguet, C. Schreiter, C. Danelon, J-M. Segura, H. Vogel & R. Hovius.
Laboratory of Physical Chemistry of Polymers and Membranes, Ecole Polytechnique Federale de Lausanne
Journal of Pharmacological Sciences 101 (suppl) 45-45, 2006.

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Serotonergic mechanisms and 5HT3 receptors in abnormal intestinal function

C A Marsden
School of Biomedical Sciences, University of Nottingham Medical School
Journal of Pharmacological Sciences 101 (suppl) 46-46, 2006.

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Serotonergic Integration of Behavioral Input to the Mammalian Circadian Timing System

J. D. Glass, G. H. Grossman
Department of Biological Sciences, Kent State University
Journal of Pharmacological Sciences 101 (suppl) 47-47, 2006.

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Differential Effects of Arousal Procedures on Circadian Clock Resetting across Species: Role of Serotonin

R. Mistlberger

Journal of Pharmacological Sciences 101 (suppl) 48-48, 2006.

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Role of 5-HTI a/ 5-HT7 receptors in central and peripheral circadian clocks

T Kudo, K Horikawa, S Shibata
Dept. Pharmacology, School of Science and Engineering, Waseda University
Journal of Pharmacological Sciences 101 (suppl) 49-49, 2006.

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Drug-induced phase shifts of SCN neuronal firing in vitro: Roles for 5HTIA, 5-HT5Aand 5HT7 receptors

J. Sprouse
Pfizer Global Research & Development, Groton, CT USA
Journal of Pharmacological Sciences 101 (suppl) 50-50, 2006.

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Medicinal Chemistry approaches toward novel, selective 5-HT6 receptor ligands

J. Holenz, P. J. Pauwels, J. L. Diaz, R. Merce, X. Codony, H. Buschmann
LABORATORIOS DR. ESTEVE, S. A.
Journal of Pharmacological Sciences 101 (suppl) 51-51, 2006.

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Increased Expression of 5HT6 Receptors in Rat Striatum Impairs Instrumental Learning

J. F. Neumaier, E. S. Mitchell
University of Washington
Journal of Pharmacological Sciences 101 (suppl) 52-52, 2006.

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Selective 5-HT6 Compounds as a Novel Approach to the Treatment of Alzheimer's Disease

KCF Fone
Institute of Neuroscience, School of Biomedical Sciences, University of Nottingham
Journal of Pharmacological Sciences 101 (suppl) 53-53, 2006.

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Selective 5-ht6 Ligands as a Novel Approach to the Treatment of Obesity and Related Metabolic Disorders

David J Heal1), Petrus J Pawels2)
1)RenaSci Consultancy Ltd, BioCity, Nottingham NG1 1 GF, UK,, 2)Laboratorios Dr Esteve SA, Av de Deu de Montserrat 221, 08041 Barcelona, Spain
Journal of Pharmacological Sciences 101 (suppl) 54-54, 2006.

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Non-classical Modes of Signaling by 5HT2C Receptors

A. Christopoulos
Department of Pharmacology, Monash University, Clayton
Journal of Pharmacological Sciences 101 (suppl) 55-55, 2006.

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PDZ-domain Proteins and 5-HT Signaling

J. Bockaert, C;Becamel, L. Joubert, S. Gavarini, A. Dumuis, P. Marin
CNRS/INSERM/Universites Montpellier
Journal of Pharmacological Sciences 101 (suppl) 56-56, 2006.

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RSK2 Exerts a Tonic Brake on 5-HT2A Signaling

BL Roth, DJ Sheffler, R Strachen
Biochemistry; CASE Western Reserve University Medical Schoo
Journal of Pharmacological Sciences 101 (suppl) 57-57, 2006.

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Calmodulin Interacts with and Modulates 5-HT1a and 5-HT2a Receptors

J. R. Raymond, A. K. Gelasco, J. H. Turner
Medical University of South Carolina and Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina, USA
Journal of Pharmacological Sciences 101 (suppl) 58-58, 2006.

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Antidepressant and Anti-anxiety Effects of the Neurotrophins BDNF and IGF-1 and their Dependence on Serotonergic Transmission

I. Lucki
University of Pennsylvania and Wyeth, Neuroscience Discovery
Journal of Pharmacological Sciences 101 (suppl) 59-59, 2006.

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Contribution of Hippocampal Neurogenesis to the Behavioral Effects of Antidepressants

R. Hen
Center For Neurobiology and Behavior, Columbia University
Journal of Pharmacological Sciences 101 (suppl) 60-60, 2006.

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The Role of Serotonin in Behavioral and Cellular Changes in CREB Deficient Mice

J. A. Blendy, A. C. Conti, A. Bechtolt, I. Lucki, J. E. Malberg
University of Pennsylvania, Wyeth Research
Journal of Pharmacological Sciences 101 (suppl) 61-61, 2006.

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The Potential Role of 5-HT6 Receptor Stimulation in Antidepressant Drug Action and Neuronal Plasticity

Lee E Schechter
Neuroscience Discovery, Wyeth Research, CN 8000, Princeton, NJ, 08543, USA
Journal of Pharmacological Sciences 101 (suppl) 62-62, 2006.

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Serotonin (5-HT) Increases and Prolongs p38 MAPK Activation in Osteoclasts

L Morse, P Stashenko, R Battaglino
Forsyth Institute, Harvard Medical School
Journal of Pharmacological Sciences 101 (suppl) 64-64, 2006.

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Functional expression of 5-HT2A receptors in mouse osteoblasts-Activation of ERK pathway by 5-HT2A receptors on osteoblastic cell proliferation-

Takao Hirai, Naoko Yoshinaga, Teruko Kurosaki, Hiroaki Nishio
Department of Molecular Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.
Journal of Pharmacological Sciences 101 (suppl) 65-65, 2006.

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Serotonergic system regulates cellular differentiation in mouse osteoblasts.

Hiroaki Nishio, Takao Hirai, Naoko Yoshinaga, Kota Kaneshige, Teruko Kurosaki, Atsuyo Fujii
Department of Molecular Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Hiroshima, Japan.
Journal of Pharmacological Sciences 101 (suppl) 66-66, 2006.

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Anti-inflammatory drugs inhibit a delayed increase of serotonin formation in rat ileum after cisplatin administration

Masahiko Hirafuji, Ju Chuanxia, Naoya Hamaue, Takuji Machida, Kenji lizuka, Masaru Minami
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan
Journal of Pharmacological Sciences 101 (suppl) 67-67, 2006.

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A 5-HT4 agonist mosapride enhances rectorectal and rectoanal reflexes in guinea pigs.

Renta Katsui1 , 2), Yu Kojima2), Hidehiko Shimatani2), Tadashi Nakagawa2), Hisao Fujii2), Yoshiyuki Nakajima2), Miyako Takaki1)
1)Departments of Physiology II, Nara Medical University, 2)Surgery, Nara Medical University
Journal of Pharmacological Sciences 101 (suppl) 68-68, 2006.

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Regulation of Gastrointestinal Pacemaker Activity Via 5-HT3 Induced Ca 2+ Influx

Hong-Nian Li1), Susumu Ohya2), Yuji Imaizumi2), Shinsuke Nakayama
1)Department of Cell Physiology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JAPAN., 2)Department of Molecular & Cellular Pharmacology Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, JAPAN.
Journal of Pharmacological Sciences 101 (suppl) 69-69, 2006.

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Human Arterial Constrictor Serotonin Receptors

0. Yildiz*, H. Gul*, R. E. Purdy#, M. Tuncer**
*Department of Pharmacology, Gulhane School of Medicine, #Department of Pharmacology, University of California Irvine, **Department of Pharmacology, Faculty of Medicine, Hacettepe University
Journal of Pharmacological Sciences 101 (suppl) 70-70, 2006.

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Enhanced inhibitory effect of 5-hydroxytryptamine on interleukin-1 fi-induced nitric oxide production by vascular smooth muscle cells derived from stroke-prone spontaneously hypertensive rats.

Takuji Machida, Naoya Hamaue, Kenji lizuka, Masaru Minami, Masahiko Hirafuji.
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan.
Journal of Pharmacological Sciences 101 (suppl) 71-71, 2006.

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CNS5/Jabl reduces L-type Ca2+ current in cardiac myocyte.

Takeshi Kobayashi(a), Kazutoshi Kameda(a, b), Mitsuhiro Fukao(a), Masaaki Tsutsuura(a), Masato Nagashima(a), Yoichi Yamada(a), Toshihiko Yamashita(b), Noritsugu Tohse(a)
(a)Department of Cellular Physiology and Signal Transduction, Sapporo Medical University School of Medicine, (b)Orthopedic Surgery, Sapporo Medical University School of Medicine
Journal of Pharmacological Sciences 101 (suppl) 72-72, 2006.

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Induction of Functional Serotonin 5-HT2A and 5-HT4 Receptors in the Acute Failing Cardiac Ventricle

Qvigstad E1, 2), Sjaastad1, 2, 3, 4), Brattelid T1, 2), Nunn C1, 2), Swift F2, 3), Birkeland JA2, 3), Krobert KA1, 2), Andersen GO1, 2, 4), Sejersted OM2, 3), Osnes J-B1'2), Levy FO1'2), Skomedal T1'2)
1)Dept. of Pharmacology, Univ. of Oslo, 2)Center for Heart Failure Res, Univ. of Oslo, 3)lnst. for Exp. Med. Res. , Univ. of Oslo, 4)Dept. of Cardiology, Ullevaal Univ. Hosp. , Oslo, Norway
Journal of Pharmacological Sciences 101 (suppl) 73-73, 2006.

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Serotonin Responsiveness through 5-HT2A and 5-HT4 Receptors is differentially Regulated in Hypertrophic and Failing Rat Cardiac Ventricle

Brattelid T1, 2), Qvigstad E1, 2), Birkeland JAK2, 3), Swift F2, 3), Bekkevold SVS1, 2), Krobert KA1, 2), Sejersted OM2, 3), Skomedal T1, 2), Osnes J-B1, 2), Levy FO1, 2), Sjaastad1, 2, 3, 4)
1)Dept. of Pharmacology, Univ. of Oslo, 2)Center for Heart Failure Res, Univ. of Oslo, 3)lnst. for Exp. Med. Res. , Univ. of Oslo, 4)Dept. of Cardiology, Ullevaal Univ. Hosp. , Oslo, Norway
Journal of Pharmacological Sciences 101 (suppl) 74-74, 2006.

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Treatment with a 5-HT4 Serotonin Receptor Antagonist Improves Function of the Failing Heart

Birkeland JAK1, 3), Sjaastad I1, 3, 4), Brattelid T2, 3), Qvigstad E2, 3), Moberg ER2, 3), Krobert KA2, 3), Bjornerheim R4), Skomedal T2, 3), Sejersted OM1, 3), Osnes J-B2, 3), Levy FO2, 3)
1Inst. for Exp. Med. Res, Univ. of Oslo, 2Dept. of Pharmacology, Univ. of Oslo, 3Center for Heart Failure Res., Univ. of Oslo, 4Dept. of Cardiology, Ullevaal Univ. Hosp., Oslo, Norway
Journal of Pharmacological Sciences 101 (suppl) 75-75, 2006.

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The 5-HT4 receptor - a foetal gene reactivated in heart failure?

Brattelid T1, '2), Bekkevold SVS1, 2), Qvigstad E1, 2), Moltzau LR1, 2), Sandnes DL1), Birkeland JAK2, 3), Sjaastad1, 2, 3, 4), Levy FO1 '2)
1)Dept. of Pharmacology, Univ. of Oslo, 2)Center for Heart Failure Res, Univ. of Oslo, 3)lnst. for Exp. Med. Res. , Univ. of Oslo, 4)Dept. of Cardiology, Ullevaal Univ. Hosp. , Oslo, Norway
Journal of Pharmacological Sciences 101 (suppl) 76-76, 2006.

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5-Htl b/l d and 5-Ht7 Receptor-Mediated Vasodilatation in the Middle Meningeal Artery of Anesthetized Rats: Effect of Lesion of the Central 5-Ht System

J. A. Terron, E. Martinez-Garcia
Cinvestav-IPN
Journal of Pharmacological Sciences 101 (suppl) 77-77, 2006.

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Potential Vascular Alphal-adrenoceptor Blocking Properties of an Array of 5-HT Receptor Ligands in the Rat

A. Sanchez-Lopez, D. Centurion, J. Lozano-Cuenca, J. A. Albarran-Juarez, E. B. Monroy-Ordonez, L. E. Cobos-Puc, C. M. Villalon.
Cinvestav-IPN
Journal of Pharmacological Sciences 101 (suppl) 78-78, 2006.

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Pharmacological Identification of the Mechanisms Involved in the Inhibition Induced by Ergotamine on the Cardioaccelerator Sympathetic Outflow in Pithed Rat

Monroy Ordonez, E. B., Cobos Puc, L. E., Albarran-Juarez, J. A., Sanchez Lopez, A., Lozano Cuenca, J., Villalon, C. M., Centurion, D.
Depto. de Farmacobiologia, Cinvestav-Coapa, 14330 Mexico D. F. , Mexico
Journal of Pharmacological Sciences 101 (suppl) 79-79, 2006.

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Modulation of maternal care by editing of the serotonin 2C receptor (5-HT2cR)

Michelle M. Jacobs1), Ronald B. Emeson1, 2)
1)Center for Molecular Neuroscience;, 2)Departments of Pharmacology and MolecularPhysiology and Biophysics; Vanderbilt University, Nashville, TN 37232, USA
Journal of Pharmacological Sciences 101 (suppl) 80-80, 2006.

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Alterations in head-twitch response to a 5-HT2A agonist in thiamine deficient mice

Takeshi Tadano, Osamu Nakagawasai, Yuichiro Arai1), Fukie Niijima, Koichi Tan-No
Department of Pharmacology, Tohoku Pharmaceutical University, Sendai 981-8558, Japan, 1)Division of Pharmacology, School of Pharmaceutical Sciences, Ohu University, Koriyama 963-8611, Japan
Journal of Pharmacological Sciences 101 (suppl) 81-81, 2006.

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Involvement of the 5-HT2 receptor subtypes in anti-immobility effects of noradrenaline and dopamine reuptake inhibitors in mice

Yumi Sugimoto, Jun Yamada
Dept. Pharmacol. Kobe Pharmaceutical University, Kobe 658-8558, Japan.
Journal of Pharmacological Sciences 101 (suppl) 82-82, 2006.

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5-Hydroxytriptamine 2 receptors in dorsomedial medulla oblongata contribute to the onset of initial hyperventilatory response to acute hypoxia in mice

Mitsuko Kanamaru, Ikuo Homma
Department of Physiology, Showa University School of Medicine, Shinagawa-ku, Tokyo 142-8555, Japan
Journal of Pharmacological Sciences 101 (suppl) 83-83, 2006.

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Chronic treatment with SSRIs desensitizes both 5-HT2A and 5-HT2c receptor function

Miki Yamauchi, Takako Miyara, Tetsuya Matsushima, Tomoko Tatebayashi, Fumikazu Yokoyama, Kaname Onozawa, Akiko Yoshida, Taiichiro Imanishi
Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd.
Journal of Pharmacological Sciences 101 (suppl) 84-84, 2006.

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Serotonin increases glial cell line-derived neurotrophic factor (GDNF) expression in C6 glioma cells: Implication in Src family-dependent fibroblast growth factor receptor (FGFR) transactivation

M. Tsuchiokaa, c), M. Takebayashia, b), K. Hisaokaa), Y. Nakatac)
a)lnstitute of Clinical Research,, b)Department of Psychiatry, National Hospital Organization Kure Medical Center, c)Department of Pharmacology, Graduate School of Biomedical Sciences, Hiroshima University
Journal of Pharmacological Sciences 101 (suppl) 85-85, 2006.

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Effect of nicotine cessation on wet-dog shakes mediated by 5-HT2A receptors in rats

Katsuya Suemaru, Ranji Cui, Nobuhito Takeuchi, Shinichi Watanabe, Bingjin Li, Hiroaki Araki
Department of Clinical Pharmacology and Pharmacy, Neuroscience, Ehime University Graduate School of Medicine
Journal of Pharmacological Sciences 101 (suppl) 86-86, 2006.

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Effects of monoamine-related drugs on the model of 5-HT2A receptor hyperfunction induced by treatment of ACTH in rats.

Yoshihisa Kitamura1), 2), Yoshika Fujitani2), Kouhei Kitagawa2), Toshiaki Miyazaki2), Kazuaki Shinomiya1), 2), Hiromu Kawasaki3), Toshiaki Sendo2), Yutaka Gomita2)
1)Department of Pharmaceutical Care and Health Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2)Department of Hospital Pharmacy, Okayama University Medical School, 3)Department of Clinical Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Journal of Pharmacological Sciences 101 (suppl) 87-87, 2006.

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Ejaculatory response induced by a 5-HT receptor agonist m-CPP in rats; differential roles of 5-HT2 receptor subtypes

Akihiko Yonezawa, Masaru Yoshizumi, Mamoru Ebiko, Shin-nosuke Ise, Yukio Kimura*, Shinobu Sakurada
Department of Physiology and Anatomy, Tohoku Pharmaceutical University, Sendai, Japan., *Towada Urology Hospital, Towada, Japan
Journal of Pharmacological Sciences 101 (suppl) 88-88, 2006.

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Altered RNA Editing of the 2C-Subtype of Serotonin Receptor (5-HT2CR) Results in Paradoxical Alterations in Feeding Behavior and Growth in Mutant Mice

Morabito MV, Emeson RB
Vanderbilt Univeristy
Journal of Pharmacological Sciences 101 (suppl) 89-89, 2006.

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Role of serotonin 5-HT2c receptor in aggressive behavior induced by social isolation in mice

Kazuhiro Takuma, Tomoko Tsuji, Hiroyuki Koike, Taku Nagai, Kiyofumi Yamada
Lab. Neuropsychopharmacol. , Grad. Sch. Nat. Sci. Technol. , Kanazawa Univ. , Kanazawa 920-1192, Japan.
Journal of Pharmacological Sciences 101 (suppl) 90-90, 2006.

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A possible Role for 5-HT2C Receptors in Postsynaptic Feedback Regulation of 5 HT Neurones

Raley, JM;, Boothman, LB;, Sharp, T
Oxford University
Journal of Pharmacological Sciences 101 (suppl) 91-91, 2006.

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RNA Editing and Short Variant of 5-HT2C Receptor in Neuronal Differentiated Cells

M. Tohda, M. Sukma, H. T. N. Pham, K. Matsumoto
Inst. of Natl. Med. , Univ. of Toyama
Journal of Pharmacological Sciences 101 (suppl) 92-92, 2006.

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Serotonergic interventions ameliorated the symptomatic abnormalities in an animal model for attention-deficit/hyperactivity disorder

Mutsuko Terado1), Kosei Ohno1), Chiho Kurumazuka1), Ken-ichi Ueno3), Taku Yamaguchi3), Naoya Hamaue1), 2), Masahiro Hirafuji1), Mitsuhiro Yoshioka3), Hiroko Togashi1), 3)
1)Dept. Pharmacol. Univ. of Hokkaido, 2)Biochem. , Fac. of Pharm. Sci, Health Sci. Univ. of Hokkaido, 3)Dept. Neuropharmacol. , Hokkaido Univ. Graduate Sch. of Med, Sapporo
Journal of Pharmacological Sciences 101 (suppl) 93-93, 2006.

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Dosing time dependent variance of anti-immobility effect of fluvoxamine in forced swimming test

Kentarou Ushijima, Hiromi Sakaguchi, Hideto To, Shigehiro Ohdo, Shun Higuchi
Clinical Pharmacokinetics, Faculty of Pharmaceutical Sciences, Kyushu University
Journal of Pharmacological Sciences 101 (suppl) 94-94, 2006.

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Nonuniform distribution of serotonin transporter in the hippocampus and neocortex of the mouse

Naoki Shigematsu1, 2), Shun Higuchil, Kenji Yamamoto2), Takaichi Fukuda3)
1)Clinical Pharmacokinetics, Division of Clinical Pharmacy, Department of Medico-Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences,, 2)Department of Pharmacology, Graduate School of Dental Science, Kyushu University, 3)Department of Anatomy and Neurobiology, Graduate School of Medical Sciences, Kyushu University,
Journal of Pharmacological Sciences 101 (suppl) 95-95, 2006.

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Buried Treasure? Is there a Function for the Esterase Activity of the Synaptic Protein that binds Paroxetine?

M M Rapport
Albert Einstein College of Medicine
Journal of Pharmacological Sciences 101 (suppl) 96-96, 2006.

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Acute and Chronic Fluoxetine Treatments Differentially Modulate Cytoskeletal Microtubule Dynamics and Serotonin Metabolism in Rat Hippocampus.

M. Bianchi*, A. J. Shah, A. R. Atkins, M. T. Ferretti, L. A. Dawson, C. A. Heidbreder, K. C. F. Fone*, J. J. Hagan, C. A. Marsden*
1)Institute of Neuroscience, Nottingham University, 2)Psychiatry CEDD, GlaxoSmithKline
Journal of Pharmacological Sciences 101 (suppl) 97-97, 2006.

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Changes in Tissue 5-HT and 5-HIAA Contents in Eleven Discrete Brain Regions after Four Days Treatment with Duloxetine, Venlafaxine, Milnacipran or Sertraline in Rats

K Muneoka, T Ogawa, S Shida
Department of Anatomy I, Showa University School of Medicine
Journal of Pharmacological Sciences 101 (suppl) 98-98, 2006.

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Altered Response to Selective Serotonin Reuptake Inhibitors in the Hippocampus of Adult BDNF Heterozygous + Mice

B. Guiard1, *, D. David1&2, J-P. Guilloux1, T. Deltheil1, P. Sokoloff3, R. Hen2, A. M. Gardier1
1:EA3544 Univ Paris-Sud, Fac Pharmacie, 2:Center for Neurobiology and Behavior, Columbia University, 3:INSERM U573, Centre Paul Broca
Journal of Pharmacological Sciences 101 (suppl) 99-99, 2006.

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The effects of antidepressants on the phenotype specific neuronal differentiation in vitro

Ukai W, Imai T, Ishii T, Kurosawa S, Yoshinaga T, Ono T, Saito S, Hashimoto E, Ikeda H, Saito T
Dept. of Neuropsychiatry, Sapporo Medical University
Journal of Pharmacological Sciences 101 (suppl) 100-100, 2006.

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Modulation of α2-adrenoceptors in the milnacipran-induced synaptic plasticity in the rat hippocampo-medial prefrontal cortex

Hiroyo Koseki2, Machiko Matsumoto1, Hiroko Togashi1, Taku Yamaguchi1, Kazuaki Fukushima2, Mitsuhiro Yoshioka1
1Department of Neuropharmacology, Graduate School of Medicine,, 2Department of Oral Pathobiological Science (Dental Anesthesiology), Graduate School of Dental Medicine, Hokkaido University
Journal of Pharmacological Sciences 101 (suppl) 101-101, 2006.

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Influence of selective serotonin reuptake inhibitors (SSRIs) upon hamster circadian activity rhythms

R. L. Gannon, M. J. Millan
Valdosta State University, Valdosta, Georgia, USA ; Institut de Recherches Servier, Croissy-sur-Seine (Paris), France
Journal of Pharmacological Sciences 101 (suppl) 102-102, 2006.

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Measuring and manipulating tph2 transcript levels in the mouse brain

G. Honig1, M. Berger2, L. Tecott2
1Neuroscience Graduate Program and, 2Department of Psychiatry, University of California at San Francisco
Journal of Pharmacological Sciences 101 (suppl) 103-103, 2006.

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Basolateral nucleus of the amygdala is the target brain site of the anxiolytic effect of citalopram, a selective serotonin reuptake inhibitor.

Takeshi Izumi1)2), Takeshi Inoue1), Akiko Kato1), Taku Yamaguchi2), Machiko Matsumoto2), Mitsuhiro Yoshioka2), Tsukasa Koyama1)
1)Department of Psychiatry, Hokkaido University School of Medicine, 2)Department of Pharmacology, Hokkaido University School of Medicine
Journal of Pharmacological Sciences 101 (suppl) 104-104, 2006.

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Involvement of 5-HT2c receptors in conditioned fear-related responses

Taku Yamaguchi1, Hiroko Togashi1, 2, Machiko Matsumoto1, Mitsuhiro Yoshioka1
1)Departments of Neuropharmacology, Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan, 2)Department of Pharmacology, Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu 061-0293, Japan
Journal of Pharmacological Sciences 101 (suppl) 105-105, 2006.

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The Mechanism of Action of Prozac (Fluoxetine) in C.elegans - Novel Pathways

Davy, J. A., Bell, D. R., Kendall, D. A.
University of Nottingham
Journal of Pharmacological Sciences 101 (suppl) 106-106, 2006.

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5-HT1A Receptors in the Amygdala are lvolved in the Regulation of Anxiety-like Behavior

Q. Li, K. Davis, Y. Liu, S. Yang
Dept. of Psychiatry and Behavioral Sciences, University of Texas Medical Branch
Journal of Pharmacological Sciences 101 (suppl) 108-108, 2006.

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Involvement of 5-HTIA receptors in the lomomotor stimulant and sensitizing effects of methamphetamine in mice

Yukio Ago1), Shigeo Nakamura1), Akemichi Baba2), Toshio Matsuda1)
1)Laboratories of Medicinal Pharmacology, 2)Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University
Journal of Pharmacological Sciences 101 (suppl) 109-109, 2006.

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Effect of a selective 5-HTIA agonist tandospirone on abnormal involuntary movements in rat L-DOPA-induced dyskinesia model

Tadashi Ishibashi, Osamu Konishi, Nobumasa Takasugi, Akira Ito
Pharmacology Research Laboratories, Dainippon Sumitomo Pharma Co.,Ltd.
Journal of Pharmacological Sciences 101 (suppl) 110-110, 2006.

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Learning and Memory Abilities of Mice Overexpressing the 5-htla Receptor in Dentate Gyrus and Cortex

B. Bert, J.-P. Voigt, H. Fink
Freie University Berlin
Journal of Pharmacological Sciences 101 (suppl) 111-111, 2006.

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Effective Adjunctive Use of Tandospirone with Perospirone for Enhancing Verbal Memory and Quality of Life in Schizophrenia: Role of Serotonin1A Agonism in Cognitive Enhancement

T. Sumiyoshi*, Y. Higuchi*, M. Matsui+, H. Arai+, C. Takamiya+, H. Y. Meltzer$, M. Kurachi*
*Department of Neuropsychiatry, University of Toyama School of Medicine, Toyama, Japan, +Department of Psychology, University of Toyama School of Medicine, Toyama, Japan, $Department of Psychiatry, Vanderbilt University Medical Center, Nashville, USA
Journal of Pharmacological Sciences 101 (suppl) 112-112, 2006.

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Amphetamine-induced attenuation of hyperactivity and prepulse inhibition deficits in mice lacking PACAP

Norihito Shintani1, Hitoshi Hashimoto1, 2, Kazuhiro Tanaka1, Yukio Ago3, Michiya Kakuda2, Toshio Matsuda2, 3, Akemichi Baba1
1Laboratories of Molecular Neuropharmacology, 2Medicinal Pharmacology, Graduate School of Pharmaceutical Sciences,, 3The Osaka-Hamamatsu Joint Research Center for Child Mental Development, Graduate School of Medicine, Osaka University
Journal of Pharmacological Sciences 101 (suppl) 113-113, 2006.

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Effects of a Galanin-3 Receptor Antagonist on Neurite Outgrowth

X.Zhang, C. A. Kachel, R.Catapano Jr., R. E. M. Scott, T. P. Blackburn*
Helicon Therapeutics, Inc. 1BioSience Park Drive, Farmingdale, NY 11735
Journal of Pharmacological Sciences 101 (suppl) 114-114, 2006.

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Electrophysiological and neurochemical characterization of milnacipran on the rat serotonergic and noradrenergic systems

Kaori Tachibana1, Machiko Matsumoto2, Mitsuhiro Yoshioka2, Yuji Morimoto1
1Department of Anesthesiology and Critical Care Medicine,, 2Department of Neuropharmacology, Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan
Journal of Pharmacological Sciences 101 (suppl) 115-115, 2006.

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Effect of the stimulation of serotonin1A (5-HT1A) receptor on neurogenesis and neuroprotection

Naoko Kuzumaki, Minoru Narita, Tsutomu Suzuki
Department of Toxicology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, JAPAN
Journal of Pharmacological Sciences 101 (suppl) 116-116, 2006.

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The Carotid Vasodilator Responses to Capsaicin are Inhibited by Donitriptan, but not by Sumatriptan, via Stimulation of 5-HT1B Receptors in a Canine Model of Migraine

J. A. Albarran-Juarez, E. Munoz-Islas, L. R. Jimenez-Mena, J. Lozano-Cuenca, E. B. Monroy-Ordonez, L. E. Cobos-Puc, A. Sanchez-Lopez, D. Centurion, C. M. Villalon.
Departamento de Farmacobiologia; Cinvestav-coapa
Journal of Pharmacological Sciences 101 (suppl) 117-117, 2006.

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Critical Role of the C-terminal Amino Acids of the Human 5-hydroxytryptamine3A Receptor Subunit

A. S. Butler, S. A. Lindsay, A. C. Dutton, T. J. Dover, A. G. Hope, N. M. Barnes.
Cellular and Molecular Neuropharmacology Research Group, Department of Pharmacology, Division of Neuroscience, The Medical School, University of Birmingham
Journal of Pharmacological Sciences 101 (suppl) 118-118, 2006.

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The Serotonin-Receptor Antagonist Ondansetron is able to Inhibit Proliferation of Acute Lymphoblastic Leukemia Cells, Putatively by Activation of a Pathway involving the inducible No-synthase (iNOS)

J. Prada, S. Shalapour, M. Pfau, G. Henze, K. Seeger
Bmfz (Biomedical Research Center), Charit Cvk, Berlin, Germany
Journal of Pharmacological Sciences 101 (suppl) 119-119, 2006.

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5-Hydroxytryptamine (5-HT) concentration in cisplatin-induced emesis

Masaru Minami1, Yanxia Liu, Toru Endo1, Masahiko Hiafuji1, Naoya Hamaue1, Hideya Saito1, Hasan S. Parvez2
1Dept. of Pharmacol. , Health Sciences Univ. of Hokkaido, 2Alfred Fressard Institute of Neuroscience
Journal of Pharmacological Sciences 101 (suppl) 120-120, 2006.

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The Human Hippocampus Displays the Potential to Express both Homomeric and Heteromeric 5-HT3 Receptors

A. N. Massoura, C. A. Brady, T. J. Dover, A. P. Princivalle, A. G. Hope, N. M. Barnes
Cellular and Molecular Neuropharmacology Research Group, Department of Pharmacology, Division of Neuroscience, The Medical School, University of Birmingham
Journal of Pharmacological Sciences 101 (suppl) 121-121, 2006.

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Paroxetine-induced emesis in suncus murinus

Masahiro Nemoto1, Akie Kamikawa1, Toru Endo2, Masahiko Hirafuji3, Masaru Minami3, Hideya Saito1, Yoshiya Ito1
1Department of Basic Sciences, Japanese Red Cross Hokkaido College of Nursing,, 2Institute of Personalized Medical Science, Health Sciences University of Hokkaido,, 3Department of Pharmacology, Health Sciences University of Hokkaido, JAPAN
Journal of Pharmacological Sciences 101 (suppl) 122-122, 2006.

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Regulation of the Human 5-ht5A Receptor Cell Surface Expression by N-glycosylation

Dutton, A. C., Andrews, A. A., Barnes, N. M.
Cellular and Molecular Neuropharmacology Research Group, Department of Pharmacology, Division of Neuroscience, The Medical School, University of Birmingham
Journal of Pharmacological Sciences 101 (suppl) 123-123, 2006.

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PRX-07034, a Potent and Selective 5-HT6 Receptor Antagonist, Reduces Food Intake and Body Weight in Rats

KS Gannon(1), DJ Heal(2), SC Cheetham(2), HC Jackson(2), RJ Seeley(3), R Melendez(1 ), M Fichman(1), JV Rutkowski(1), S Shacham(1), P Orbach(1)
(1)Predix Pharmaceuticals, 4 Maguire Road, Lexington, MA 02421, USA., (2)RenaSci Consultancy Ltd, Nottingham, NG1 1GF, UK., (3)Department of Psychiatry, Genome Research Institute, University of Cincinnati, Cincinnati, Ohio, USA.
Journal of Pharmacological Sciences 101 (suppl) 124-124, 2006.

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Influence of Median or Dorsal Raphe 5, 7-DHT Lesions on 5-ht6 Receptor Antagonist Activity in a Novel Object Discrimination Paradigm

King MV(1), Spicer CH(1), Sleight AJ(2), Fone KCF(1), Marsden CA(1)
(1)Institute of Neuroscience, School of Biomedical Sciences, University of Nottingham Medical School, QMC ,, (2)PRBD-N, F. Hoffmann-La Roche
Journal of Pharmacological Sciences 101 (suppl) 125-125, 2006.

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5-HT6 Receptor Over-expression in the Striatum Decreases Autoshaped Learning

E. S. Mitchell, T. Sexton, J. F. Neumaier
University of Washington
Journal of Pharmacological Sciences 101 (suppl) 126-126, 2006.

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An Investigation of 5-HT7 mRNA Expression in Hamster Brain during Aging

M. J. Duncan, V. A. Davis, K. M. Franklin
University of Kentucky Medical Center
Journal of Pharmacological Sciences 101 (suppl) 127-127, 2006.

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Activation of Adenylyl Cyclase in HEK293 Cells by Endogenous Gs-coupled Receptors is attenuated by 5-HT7 Receptor Expression

Andressen KW, Norum JH, Levy FO, Krobert KA
Department of Pharmacology, University of Oslo, N-0316 Oslo, Norway
Journal of Pharmacological Sciences 101 (suppl) 128-128, 2006.

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Rat Brain ex vivo Binding Method Allows for the Determination of CNS Penetrance and Potency of 5-HT7 Receptor Ligands

JF Falcone, FP Bymaster, J Witkin, JM Schaus, D Thompson, K Svensson
Eli Lilly & Co
Journal of Pharmacological Sciences 101 (suppl) 129-129, 2006.

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Involvement of Spinal 5-Ht7, but not 5-Ht1a Receptors in the Systemic Morphine Antinociception

A. Dogrul, M. Seyrek
Department of Pharmacology, Gulhane School of Medicine, 06018 Etlik, Ankara, Turkey
Journal of Pharmacological Sciences 101 (suppl) 130-130, 2006.

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Noradrenergic transmission within the central amygdaloid nucleus contributes to the negative affective component of visceral pain in rats

Satoshi Deyama1, 3, Azusa Takishita1, Takayuki Nakagawa1, Sachi Tanimoto1, Shuji Kaneko1, Masamichi Satoh2, Masabumi Minami3
1Dept. of Mol. Pharmacol. , Grad. Sch. of Pharm. Sci. , Kyoto Univ, 2Yasuda Women's Univ, Hiroshima, 3Dept. of Pharmacol, Grad. Sch. of Pharm. Sci, Hokkaido Univ
Journal of Pharmacological Sciences 101 (suppl) 131-131, 2006.

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Role of noradrenergic transmission within the bed nucleus of the stria terminals in visceral pain-related aversion in rats

Naomi Akiyama1, Satoshi Deyama1, 2, Mikie Hirata1, Takayuki Nakagawa2, Shuji Kaneko2, Masabumi Minami1
1Dept. of Pharmacol. , Grad. Sch. of Pharm. Sci. , Hokkaido Univ. , Sapporo 060-0812, Japan, 2Dept. of Mol. Pharmacol. , Grad. Sch. of Pharm. Sci. , Kyoto Univ. , Kyoto 606-8501, Japan
Journal of Pharmacological Sciences 101 (suppl) 132-132, 2006.

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Role of noradrenergic transmission within the bed nucleus of the stria terminals in somatic pain-related aversion in rats

Mikie Hirata1, Satoshi Deyama1, 2, Naomi Akiyama1, Takayuki Nakagawa1, Shuji Kaneko2, Masabumi Minami1
1Dept. of Pharmacol. , Grad. Sch. of Pharm. Sci. , Hokkaido Univ. , Sapporo 060-0812, Japan, 2Dept. of Mol. Pharmacol. , Grad. Sch. of Pharm. Sci. , Kyoto Univ. , Kyoto 606-8501, Japan
Journal of Pharmacological Sciences 101 (suppl) 133-133, 2006.

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5-Hydroxytryptamine Potentiates Transient Receptor Potential V1 Functions in Rat Primary Sensory Neurons

Toshio Ohta, Yuki Ikemi, Matsuka Murakami, Ken-ichi Otsuguro, Shigeo Ito
Lab. Pharmacol. , Grad. Sch. Vet. Med. , Hokkaido Univ. , 0600818 Japan.
Journal of Pharmacological Sciences 101 (suppl) 134-134, 2006.

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Serotonergic profile of a Parkinson disease model rat infected with Japanese encephalitis virus

Naoya Hamaue1), Mutsuko Terado1), Kenji Iizuka1), Hiroko Togashi1), Kunio Tashiro2), Akihiko Ogata3), Masahiko Hirafuji1), Masaru Minami1)
1)Dept. Pharmacol. , Fac. of Pharm. Sci. , Health Sci. Univ. of Hokkaido, 2)Sch. of Psycol. Sci. , Health Sci. Univ. of Hokkaido, 3)Dept. Neurol. , Hokkaido Univ. Grad. Sch. of Med.
Journal of Pharmacological Sciences 101 (suppl) 135-135, 2006.

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5-HT Transporter Affinities for Pethidine and Norpethidine, and Their Role in Serotonin Syndrome

EJ Mylecharane*, G Cunningham, D Haggart+, I Berzetei-Gurske+
*Department of Pharmacology, University of Sydney, +Biosciences Division, SRI International
Journal of Pharmacological Sciences 101 (suppl) 136-136, 2006.

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Effects of co-administration of antidepressants and monoamine oxidase inhibitors on 5-HT-related behavior in rats

Nobuyuki Iwamoto, Yuii Kitaichi, Akiko Kato, Takeshi Inoue, Tsukasa Koyama
Department of Psychiatry, Hokkaido University Graduate School of Medicine
Journal of Pharmacological Sciences 101 (suppl) 137-137, 2006.

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The Involvement of Serotonin in the Dorsal Hippocampus in Nmda Receptor Antagonist-Induced Locomotor Hyperactivity is Specific to Phencyclidine and not Mk-801

Wendy Adams(1, 2), Snezana Kusljic(1), Maarten van den Buuse(1, 2)
(1)Behavioural Neuroscience Laboratory, Mental Health Research Institute of Victoria, (2)Centre for Neuroscience, University of Melbourne
Journal of Pharmacological Sciences 101 (suppl) 138-138, 2006.

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Effects of serotonin on membrane potential of postnatal developing neurons of prefrontal cortex among Wistar rat substrains

Atsuko Ohashi1), Junko Ishida, Taku Yamaguchi2), Hiroko Togashi3), Mitsuhiro Yoshioka2), Keiichi Shimamura1)
1)Department of Clinical Pharmacology, Faculty pf Pharmaceutical Sciences, Health Sciences University of Hokkaido,, 2)Department of Neuropharmacology, Hokkaido University Graduate School of Medicine,, 3)Department of Clinical Physiology, Faculty pf Pharmaceutical Sciences, Health Sciences University of Hokkaido
Journal of Pharmacological Sciences 101 (suppl) 139-139, 2006.

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Involvement of Serotonergic System in Early Postnatal Stress-induced Emotional Susceptibility at Postadolescent Period of Rats

Kohtarou Konno1), Machiko Matsumoto1), Hiroko Togashi2), Taku Yamaguchi1), Mitsuhiro Yoshioka1)
1)Dept Neuropharmacol, Hokkaido Univ Grad Sch Med, Sapporo,, 2)Dept Pharmacol, Sch Pharmaceut Sci, Hlth Sci Univ Hokkaido, lshikari-Tobetsu
Journal of Pharmacological Sciences 101 (suppl) 140-140, 2006.

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A possible model of depression: recoveries from reduction in 5-HT release in the amygdala and disturbance of circadian rhythm of activity induced by the chronic dexamethasone infusion in rats

Norifumi Shimizu1, Nobuo Izumo2, Minehiro Moriyama1, Shigenori Watanabe1, Chiaki Hara1
1Dept. Pharmacol. , Daiichi Univ. Coll. Pharmaceut. Sci. , Fukuoka, JAPAN, 2Dept. Clin. Pharmacol. , Yokohama Coll. Pharm. , Kanagawa, JAPAN
Journal of Pharmacological Sciences 101 (suppl) 141-141, 2006.

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Change of AP-1 in brain of dexamethasone infusion rats

Nobuo Izumo1, Norifumi Shimizu2, Minehiro Moriyama2, Shigenori Watanabe2, Chiaki Hara2
1Dept. Clin. Pharmacol. , Yokohama Coll. Pharm. , Kanagawa, 2Dept. Pharmacol. , Daiichi Univ. Coll. Pharmaceut. Sci. , Fukuoka
Journal of Pharmacological Sciences 101 (suppl) 142-142, 2006.

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Effects of diabetes on stress-induced 5-HT secretion in the medial prefrontal cortex and freezina behavior in mice

Shigeo Miyata, Naoko Yamada, Shoko Hirano, Junzo Kamei
Dept. of Pathophysiol. and Therap. , Sch. of Pharm. and Pharm. Sci. , Hoshi Univ, Tokyo
Journal of Pharmacological Sciences 101 (suppl) 143-143, 2006.

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Evidence for a Link between Brain Angiotensin, Serotonin and Behavior

J. -P. Voigt, M. Bader, H. Hoertnagl, A. Rex, H. Fink
Institute of Pharmacology and Toxicology, School of Veterinary Medicine, Freie University Max-Delbruck-Center for Molecular Medicine (MDC) Institute of Pharmacology and Toxicology, Medical Faculty of the Humboldt University
Journal of Pharmacological Sciences 101 (suppl) 144-144, 2006.

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Behavioral stress and activated serotonergic neurotransmission induce XBP-1 splicing in the rat brain

Hiroyuki Toda(a), Go Suzuki(a), Masashi Nibuya(a*), Katsutoshi Shioda(b), Koichi Nishijima(b), Tomoki Wakizono(a), Yasunari Kanda(c), Yasuhiro Watanabe(c), Kunio Shimizu(d), Soichiro Nomura(a)
(a:)Department of Psychiatry, National Defense Medical College, Namiki 3-2, Tokorozawa, Saitama, 359-8513, Japan, (b:)Department of Psychiatry, Jichi Medical School, Minamikawachi 3311-1, Tochigi, 329-0498, Japan, (c:)Department of Pharmacology, National Defense Medical College, (d:)Division of Behavioral Sciences, National Defense Medical College Research Institute
Journal of Pharmacological Sciences 101 (suppl) 145-145, 2006.

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Effects of Fluoxetine and Imipramine on Behavioral, Neuroendocrine and Neurochemical Effects of Chronic Mild Stress in Mice

S. K. Hemrick-Luecke, X. Li, L. K. Thompson, D. C. Evans, J. M. Witkin
Eli Lilly and Company
Journal of Pharmacological Sciences 101 (suppl) 146-146, 2006.

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Changes in emotional behavior of mice in the hole-board test after olfactory bulbectomy

Akiyoshi Saitoh1, Noritaka Hirose1, Mitsuhiko Yamada2, Misa Yamada2, Takuma Oka1, Junzo Kamei1
1Dept. Pathophysiol. Ther. , Sch. Pharm. Pharm. Sci. , Hoshi Univ. , Tokyo, Japan, 2Dept. Psychogeriatr. , NINH. , NCNP. , Tokyo, Japan
Journal of Pharmacological Sciences 101 (suppl) 147-147, 2006.

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The Role of the CREB Pathway in Controlling 5-HT Neuron Activity and Emotional Behavior

M Berger
Dept of Psychiatry, University of California, San Francisco (USA)
Journal of Pharmacological Sciences 101 (suppl) 148-148, 2006.

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Effects of supplemental administration of 5-HT2 receptor antagonist on glucose metabolism in KK-Ay mice treated with pioglitazone.

Kenji Iizuka1), Naoya Hamaue1), Takuji Machida1), Masahiro Tsuji2), Masahiko Hirafuji1)
1)Dept. Pharmacol. , Fac. of Pharm. Sci, 2)Personalized Health Science Center, Health Sci. Univ. of Hokkaido
Journal of Pharmacological Sciences 101 (suppl) 149-149, 2006.

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Combination of sub-threshold doses of Aricept and PRX-07034, a novel 5-HT6 receptor antagonist, enhances Novel Object Discrimination (NOD) memory_

MV King1, KCF Fone1, S Shacham2, M Fichman2, R Melendez2, P Orbach2, KS Gannon2
1Institute of Neuroscience, University of Nottingham, QMC, 2Predix Pharmaceuticals
Journal of Pharmacological Sciences 101 (suppl) 150-150, 2006.

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