バックナンバー:DRUG METABOLISM AND PHARMACOKINETICS

DRUG METABOLISM AND PHARMACOKINETICS
17巻 5号

  • Safety Evaluation and Drug Development based on Biological Fate of Drugs

    Takashi MATSUBARA
    Department of Chemical Biology. Osaka City University Medical School
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 379-394, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Application of In Vivo Brain Microdialysis to the Study of Blood-Brain Barrier Transport of Drugs

    Yoshiharu DEGUCHI
    Department of Drug Disposition & Pharmacokinetics. School of Pharmaceutical Sciences. Teikyo University.
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 395-407, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • New Methods to Evaluate Intestinal Drug Absorption Mediated by Oligopeptide Transporter from In vitro Study using Caco-2 Cells

    Shinji YAMASHITA, Emiko HATTORI, Aiko SHIMADA, Yoriko ENDOH, Yukako YAMAZAKI, Makoto KATAOKA, Toshiyasu SAKANE, Hitoshi SEZAKI
    Faculty of Pharmaceutical Sciences. Setsunan University.
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 408-415, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Evidence for Singlet Oxygen Involvement in Rat and Human Cytochrome P450-dependent Substrate Oxidations

    Hiroyuki YASUI1, Kazuko DEO1, Yuko OGURA1, Hiromi YOSHIDA1, Toshifumi SHIRAGA2, Akira KAGAYAMA2, Hiromu SAKURAI1
    1Department of Analytical and Bioinorganic Chemistry. Kyoto Pharmaceutical University., 2Biopharmaceutical and Pharmacokinetic Research Laboratories. Fujisawa Pharmaceutical Co. , Ltd.
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 416-426, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Species Difference in Nisoldipine Oxidation Activity in the Small Intestine

    Hiroshi KOMURA1, Motoko YASUDA1, Nagahiro H. YOSHIDA1, Yuichi SUGIYAMA2
    1Department of Pharmacokinetics. Research Center Kyoto. Bayer Yakuhin, 2Graduate School of Pharmaceutical Sciences. University of Tokyo.
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 427-436, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Application of Microtiter Plate Assay to Evaluate Inhibitory Effects of Various Compounds on Nine Cytochrome P450 Isoforms and to Estimate their Inhibition Patterns

    Takahito YAMAMOTO, Akio SUZUKI, Yoshiro KOHNO
    Department of Drug Metabolism. Medicinal Research Laboratory, Taisho Pharmaceutical Co. , Ltd.
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 437-448, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Metabolic Fate of Pitavastatin, a New Inhibitor of HMG-CoA Reductase Effect of cMOAT Deficiency on Hepatobiliary Excretion in Rats and of mdr1a/b Gene Disruption on Tissue Distribution in Mice

    Hideki FUJINO, Iwao YAMADA, Syunsuke SHIMADA, Junji KOJIMA
    Tokyo New Drug Research Laboratories I, Kowa Company Ltd.
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 449-456, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Formation of a Structurally Novel. Serial Diglucuronide of 4-Hydroxybiphenyl by Further Glucuronidation of a Monoglucuronide in Dog Liver Microsomes

    Takahiro MURAI, Fujiko TSURUTA, Toshio TERAO, Toshihiko IKEDA, Haruo IWABUCHI
    Pharmacokinetics and Drug Delivery Research Laboratories. Sankyo Co. , Ltd.
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 457-466, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Effects of St John's Wort and Hypericin on Cytotoxicity of Anticancer Drugs.

    Atsushi WADA1, Toshiyuki SAKAEDA2, Kohji TAKARA3, Midori HIRAI1, Takashi KIMURA1, Nobuko OHMOTO2, Jie ZHOU2, Tsutomu NAKAMURA2, Hironao KOBAYASHI4, Noboru OKAMURA4, Tatsurou YAGAMI4, Katsuhiko OKUMURA2
    1Department of Clinical Pharmacy, Kobe Pharmaceutical University., 2Department of Hospital Pharmacy. School of Medicine, Kobe University., 3Department of Hospital Pharmacy. Faculty of Pharmaceutical Sciences, Kyoto Pharmaceutical University., 4Shionogi Research Laboratories. Shionogi & Co. , Ltd.
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 467-474, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Novel single nucleotide polymorphisms in the CYP2D6 gene associated with CYP2D6*2 and/or CYP2D6*10 alleles

    Akiko SOYAMA, Yoshiro SAITO1, Kazuo KOMAMURA2, 3, Kazuyuki UENO4, Shiro KAMAKURA2, Shogo OZAWA5, Jun-ichi SAWADA1
    Project team for Pharmacogenetics,National Institute of Health Sciences, 1Division of Biochemistry and Immunochemistry.National Institute of Health Sciences, 5Division of Pharmacology. National Institute of Health Sciences., 2Department of Cardiology National Cardiovascular Center, 3Department of Cardiovascular Dynamics Research Institute National Cardiovascular Center, 4Department of Pharmacy. National Cardiovascular Center.
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 475-478, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
    全文ダウンロード(2.48MB)】 従量制、基本料金制の方共に660円(税込) です。

  • Polymorphism of MDR1 Gene in Healthy Japanese Subjects: A Novel SNP with an Amino Acid Substitution (Glu108Lys)

    Tomohiro HONDA1, Yukihiko DAN1, Noriko KOYABU1, Ichiro IEIRI2, Kenji OTSUBO2, Shun HIGUCHI3, Hisakazu OHTANI1, Yasufumi SAWADA1
    1Division of Biopharmaceutics. Department of Medico-Pharmaceutical Sciences. Graduate School of Pharmaceutical Sciences. Kyushu University., 2Department of Hospital Pharmacy. Faculty of Medicine. Tottori University., 3Division of Clinical Pharmacokinetics. Department of Medico-Pharmaceutical Sciences. Graduate School of Pharmaceutical Sciences. Kyushu University.
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 479-481, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Twenty One Novel Single Nucleotide Polymorphisms (SNPs) of the CYP2A6 Gene in Japanese and Caucasians

    Kazuma KIYOTANI1, Masaki FUJIEDA1, Hiroshi YAMAZAKI1, Tsutomu SHIMADA2, F. Peter GUENGERICH3, Andrew PARKINSON4, Kazuko NAKAGAWA5, Takashi ISHIZAKI5, Tetsuya KAMATAKI1
    1Laboratory of Drug Metabolism. Graduate School of Pharmaceutical Sciences. Hokkaido University., 20saka Prefectural Institute of Public Health., 3Vanderbilt University School of Medicine. Nashville. TN. USA, 4Xenotech. Lenexa. KS. USA, 5Kumamoto University.
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 482-487, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Three novel single nucleotide polymorphisms in UGT1A 10

    Mayumi SAEKI1, Shogo OZAWA1, 2, Yoshiro SAITO1, 3, Hideto JINNO1, 4, Tetsuya HAMAGUCHI5, Hiroshi NOKIHARA6, Yasuhiro SHIMADA5, Hideo KUNITOH6, Noboru YAMAMOTO6, Yuichiro OHE6, Yasuhide YAMADA5, Kuniaki SHIRAO5, Manabu MUTO7, Kiyomi MERA7, Koichi GOTO8, Hironobu OHMATSU8, Kaoru KUBOTA8, Seiji NIHO8, Ryutaro KAKINUMA8, Hironobu MINAMI9, Atsushi OHTSU7, Teruhiko YOSHIDA10, Nagahiro SAIJO11, Jun-ichi SAWADA1,3
    1Project Team for Pharmacogenetics., 2Division of Pharmacology., 3Division of Biochemistry and Immunochemistry., 4Division of Environmental Chemistry. National Institute of Health Sciences., 5Gastrointestinal Oncology Division., 6Thoracic Oncology Division., 11Medical Oncology Division. National Cancer Center Hospital., 10Genetics Division. National Cancer Center Research Institute. Tokyo. Japan., 7Division of GI Oncology/Digestive Endoscopy., 8Division of Thoracic Oncology., 9Division of Oncology/Hematology. National Cancer Center Hospital East.
    DRUG METABOLISM AND PHARMACOKINETICS 17(5): 488-490, 2002.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
    全文ダウンロード(2.30MB)】 従量制、基本料金制の方共に660円(税込) です。

book
発行元:
日本薬物動態学会
ISSN:
1347-4367
ISSN(オンライン):
1880-0920
前雑誌:
薬物動態

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