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Functional Evaluation of ABCB1 (P-Glycoprotein) Polymorphisms： High-Speed Screening and Structure-Activity Relationship Analyses
Toshihisa ISHIKAWA 1, Hiroyuki HIRANO 2, Yuko ONISHI 1, 2, Aki SAKURAI 1, Shigeki TARUI 2
1 Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan, 2 GS PlatZ Co. Ltd., Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 1-14, 2004.
1 Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan, 2 GS PlatZ Co. Ltd., Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 1-14, 2004.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Pharmacokinetic Comparison of an Angiotensin II Receptor Antagonist, Telmisartan, in Japanese and Western Hypertensive Patients Using Population Pharmacokinetic Method
Shinji TATAMI 1, Norio YAMAMURA 1, Akiko SARASHINA 1, Chan-Loi YONG 2, Takashi IGARASHI 1, Yusuke TANIGAWARA 3
1 Department of Drug Metabolism and Pharmacokinetics, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co., Ltd., Kawanishi, Japan, 2 Department of Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals Inc., CT, USA, 3 Department of Hospital Pharmacy, School of Medicine, Keio University, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 15-23, 2004.
1 Department of Drug Metabolism and Pharmacokinetics, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co., Ltd., Kawanishi, Japan, 2 Department of Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals Inc., CT, USA, 3 Department of Hospital Pharmacy, School of Medicine, Keio University, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 15-23, 2004.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Relationship between Pharmacokinetic Parameters and Occurrence of Adverse Events in Clinical Trials Performed in Europe and United States for an Angiotensin II Receptor Antagonist, Telmisartan
Shinji TATAMI 1, Akiko SARASHINA 1, Norio YAMAMURA 1, Takashi IGARASHI 1, Yusuke TANIGAWARA 2
1 Department of Drug Metabolism and Pharmacokinetics, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co., Ltd., Kawanishi, Japan, 2 Department of Hospital Pharmacy, School of Medicine, Keio University, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 24-32, 2004.
1 Department of Drug Metabolism and Pharmacokinetics, Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co., Ltd., Kawanishi, Japan, 2 Department of Hospital Pharmacy, School of Medicine, Keio University, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 24-32, 2004.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Lipopolysaccharide Transport System across Colonic Epithelial Cells in Normal and Infective Rat
Mikio TOMITA, Rie OHKUBO, Masahiro HAYASHI
Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, JAPAN
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 33-40, 2004.
Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, JAPAN
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 33-40, 2004.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Decreased Expression of Glucose and Peptide Transporters in Rat Remnant Kidney
Nobuhiko NAKAMURA, Satohiro MASUDA, Kazushige TAKAHASHI, Hideyuki SAITO, Masahiro OKUDA, Ken-ichi INUI
Department of Pharmacy, Kyoto University Hospital, Faculty of Medicine, Kyoto University, Kyoto, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 41-47, 2004.
Department of Pharmacy, Kyoto University Hospital, Faculty of Medicine, Kyoto University, Kyoto, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 41-47, 2004.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Transepithelial Permeation of Tolbutamide across the Human Intestinal Cell Line, Caco-2
Nobuhiro NISHIMURA, Kohji NAORA, Tomochika UEMURA, Hidenari HIRANO, Kikuo IWAMOTO
Department of Pharmacy, Shimane University Hospital, Izumo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 48-54, 2004.
Department of Pharmacy, Shimane University Hospital, Izumo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 48-54, 2004.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Utility of Microtiter Plate Assays for Human Cytochrome P450 Inhibition Studies in Drug Discovery：Application of Simple Method for Detecting Quasi-irreversible and Irreversible Inhibitors
Yoichi NARITOMI, Yuriko TERAMURA, Shigeyuki TERASHITA, Akira KAGAYAMA
Biopharmaceutical and Pharmacokinetic Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Osaka, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 55-61, 2004.
Biopharmaceutical and Pharmacokinetic Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Osaka, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 55-61, 2004.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
The Effects of Emulsifying Agents on Disposition of Lipid-Soluble Drugs Included in Fat Emulsion
Yasuyuki SUZUKI 1, Yasushi MASUMITSU 1, Kazuho OKUDAIRA 2, Masahiro HAYASHI 3
1 Faculty of Pharmaceutical Sciences, Tokyo University of Science, Tokyo, Japan, 2 Faculty of Pharmaceutical Sciences, Toho University, Chiba, Japan, 3 School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 62-67, 2004.
1 Faculty of Pharmaceutical Sciences, Tokyo University of Science, Tokyo, Japan, 2 Faculty of Pharmaceutical Sciences, Toho University, Chiba, Japan, 3 School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 62-67, 2004.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Protective Effect of Inactive Ingredients against Nephrotoxicity of Vancomycin Hydrochloride in Rats
Naoko HODOSHIMA*, Yoshihisa NAKANO, Masaaki IZUMI, Nayu MITOMI, Yukari NAKAMURA, Makoto AOKI, Akiko GYOBU, Shigeki SHIBASAKI, Toru KUROSAWA
* Toxicology & Pharmacokinetics Research Labs., Pharmaceutical Development Department, Meiji Seika Kaisha, Ltd.
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 68-75, 2004.
* Toxicology & Pharmacokinetics Research Labs., Pharmaceutical Development Department, Meiji Seika Kaisha, Ltd.
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 68-75, 2004.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Proapoptotic Effect of a Dietary Supplement：Water Soluble Chitosan Activates Caspase-8 and Modulating Death Receptor Expression
Hiroyuki TAKIMOTO 1, Masumi HASEGAWA 1, Keiko YAGI 1, Tsutomu NAKAMURA 2, Toshiyuki SAKAEDA 2, Midori HIRAI 1
1 Department of Clinical Pharmacy, Kobe Pharmaceutical University, Kobe, Japan, 2 Department of Hospital Pharmacy, School of Medicine, Kobe University, Kobe, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 76-82, 2004.
1 Department of Clinical Pharmacy, Kobe Pharmaceutical University, Kobe, Japan, 2 Department of Hospital Pharmacy, School of Medicine, Kobe University, Kobe, Japan
DRUG METABOLISM AND PHARMACOKINETICS 19 (1) 76-82, 2004.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
