書籍情報から探す
Interindividual Variability in Nicotine Metabolism： C-Oxidation and Glucuronidation
Miki NAKAJIMA, Tsuyoshi YOKOI
Drug Metabolism and Toxicology, Division of Pharmaceutical Sciences, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 227-235, 2005.
Drug Metabolism and Toxicology, Division of Pharmaceutical Sciences, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 227-235, 2005.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
The Quantitative Prediction of In Vivo Enzyme-Induction Caused by Drug Exposure from In Vitro Information on Human Hepatocytes
Motohiro KATO1, Koji CHIBA2, Masato HORIKAWA3, Yuichi SUGIYAMA4
1 Chugai Pharmaceutical Co. Ltd., Gotemba, Japan, 2 Pfizer Japan Inc., Tokyo, Japan, 3 Nissan Chemical Industries Ltd. , Saitama, Japan, 4 Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 236-243, 2005.
1 Chugai Pharmaceutical Co. Ltd., Gotemba, Japan, 2 Pfizer Japan Inc., Tokyo, Japan, 3 Nissan Chemical Industries Ltd. , Saitama, Japan, 4 Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 236-243, 2005.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
The Novel Formulation Design of Self-emulsifying Drug Delivery Systems (SEDDS) Type O/W Microemulsion I： Enhancing Effects on Oral Bioavailability of Poorly Water Soluble Compounds in Rats and Beagle Dogs
Hiroshi ARAYA1, Shunsuke NAGAO2, Mikio TOMITA3, Masahiro HAYASHI3
1 Formulation Technology Research Department, Pharmaceutical Technology Division, Chugai Pharmaceutical Co., Ltd., Tokyo, JAPAN, 2 Pre-clinical Research Department, Research Division, Chugai Pharmaceutical Co., Ltd., Shizuoka, Japan, 3 Department of Drug Absorption and Pharmacokinetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, JAPAN
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 244-256, 2005.
1 Formulation Technology Research Department, Pharmaceutical Technology Division, Chugai Pharmaceutical Co., Ltd., Tokyo, JAPAN, 2 Pre-clinical Research Department, Research Division, Chugai Pharmaceutical Co., Ltd., Shizuoka, Japan, 3 Department of Drug Absorption and Pharmacokinetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, JAPAN
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 244-256, 2005.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
The Novel Formulation Design of Self-emulsifying Drug Delivery Systems (SEDDS) Type O/W Microemulsion II: Stable Gastrointestinal Absorption of a Poorly Water Soluble New Compound, ER-1258 in Bile-fistula Rats
Hiroshi ARAYA1, Mikio TOMITA2, Masahiro HAYASHI2
1 Formulation Technology Research Department, Pharmaceutical Technology Division, Chugai Pharmaceutical Co., Ltd., Tokyo, JAPAN, 2 Department of Drug Absorption and Pharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, JAPAN
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 257-267, 2005.
1 Formulation Technology Research Department, Pharmaceutical Technology Division, Chugai Pharmaceutical Co., Ltd., Tokyo, JAPAN, 2 Department of Drug Absorption and Pharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, JAPAN
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 257-267, 2005.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
The Effects of Culture Conditions on CYP3A4 and MDR1 mRNA Induction by 1α,25-Dihydroxyvitamin D3 in Human Intestinal Cell Lines, Caco-2 and LS180
Tetsuya AIBA, Mitsuru SUSA, Shiro FUKUMORI, Yukiya HASHIMOTO
Graduate School of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Sugitani, Toyama, Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 268-274, 2005.
Graduate School of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Sugitani, Toyama, Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 268-274, 2005.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Pharmacokinetic Analysis of the Tissue Distribution of Octaarginine Modified Liposomes in Mice
Diky MUDHAKIR1, 2, Hidetaka AKITA1, 2, Ikramy A. KHALIL1, 2, Shiroh FUTAKI3, 4, Hideyoshi HARASHIMA1, 2
1 Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan, 2 CREST, Japan Science and Technology Corporation (JST), Japan, 3 Institute for Chemical Research, Kyoto University, Uji, Kyoto, Japan, 4 PREST, Japan Science and Technology Corporation (JST), Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 275-281, 2005.
1 Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan, 2 CREST, Japan Science and Technology Corporation (JST), Japan, 3 Institute for Chemical Research, Kyoto University, Uji, Kyoto, Japan, 4 PREST, Japan Science and Technology Corporation (JST), Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 275-281, 2005.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Repeated Glucuronidation at One Hydroxyl Group Leads to Structurally Novel Diglucuronides of Steroid Sex Hormones
Takahiro MURAI, Haruo IWABUCHI, Toshihiko IKEDA
Drug Metabolism and Pharmacokinetics Research Laboratories, Sankyo Co., Ltd., Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 282-293, 2005.
Drug Metabolism and Pharmacokinetics Research Laboratories, Sankyo Co., Ltd., Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 282-293, 2005.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Two Novel Single Nucleotide Polymorphisms (SNPs) of the CYP2D6 Gene in Japanese Individuals
Aiko EBISAWA, Masahiro HIRATSUKA, Kanako SAKUYAMA, Yumiko KONNO, Takamitsu SASAKI, Michinao MIZUGAKI
Department of Clinical Pharmaceutics, Tohoku Pharmaceutical University, Sendai, Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 294-299, 2005.
Department of Clinical Pharmaceutics, Tohoku Pharmaceutical University, Sendai, Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 294-299, 2005.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Genetic Variations and Haplotypes of CYP2C19 in a Japanese Population
Hiromi FUKUSHIMA-UESAKA1, Yoshiro SAITO1, 2, Keiko MAEKAWA1, 2, Shogo OZAWA1, 3, Ryuichi HASEGAWA4, Hiroshi KAJIO5, Nobuaki KUZUYA5, Kazuki YASUDA6, Manabu KAWAMOTO7, Naoyuki KAMATANI7, Kazuko SUZUKI8, Tatsuo YANAGAWA8, Masahiro TOHKIN1, 4, Jun-ichi SAWADA1, 2
1 Project Team for Pharmacogenetics, National Institute of Health Sciences, Tokyo, Japan, 2 Division of Biochemistry and Immunochemistry, National Institute of Health Sciences, Tokyo, Japan, 3 Division of Pharmacology, National Institute of Health Sciences, Tokyo, Japan, 4 Division of Medicinal Safety Science, National Institute of Health Sciences, Tokyo, Japan, 5 Division of Endocrine and Metabolic Diseases, the Hospital, 6 Department of Metabolic Disorder, Research Institute, International Medical Center of Japan, Toyko, Japan, 7 Division of Genomic Medicine, Department of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan, 8 Nerima General Hospital, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 300-307, 2005.
1 Project Team for Pharmacogenetics, National Institute of Health Sciences, Tokyo, Japan, 2 Division of Biochemistry and Immunochemistry, National Institute of Health Sciences, Tokyo, Japan, 3 Division of Pharmacology, National Institute of Health Sciences, Tokyo, Japan, 4 Division of Medicinal Safety Science, National Institute of Health Sciences, Tokyo, Japan, 5 Division of Endocrine and Metabolic Diseases, the Hospital, 6 Department of Metabolic Disorder, Research Institute, International Medical Center of Japan, Toyko, Japan, 7 Division of Genomic Medicine, Department of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan, 8 Nerima General Hospital, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 20 (4) 300-307, 2005.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
