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Human Carboxylesterase Isozymes：Catalytic Properties and Rational Drug Design
Teruko IMAI
Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 173-185, 2006.
Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 173-185, 2006.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Characterization of Prostaglandin E1 Transport in Rat Renal Brush-border Membrane
Junya NAGAI, Takanori TAOGOSHI, Akiko TOKUNAGA, Hiroaki NISHIKAWA, Teruo MURAKAMI, Mikihisa TAKANO
Department of Pharmaceutics and Therapeutics, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 186-193, 2006.
Department of Pharmaceutics and Therapeutics, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 186-193, 2006.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Genotype-dependent Down-regulation of Gene Expression and Function of MDR1 in Human Peripheral Blood Mononuclear Cells under Acute Inflammation
Svetlana MARKOVA1, Tsutomu NAKAMURA2, Toshiyuki SAKAEDA1, 2, Hiroo MAKIMOTO2, Hitoshi UCHIYAMA1, Noboru OKAMURA3, Katsuhiko OKUMURA1, 2, 3
1Division of Clinical Pharmacokinetics, Kobe University Graduate School of Medicine, Kobe, Japan, 2Department of Hospital Pharmacy, School of Medicine, Kobe University, Kobe, Japan, 3Department of Clinical Evaluation of Pharmacotherapy, Kobe University Graduate School of Medicine, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 194-200, 2006.
1Division of Clinical Pharmacokinetics, Kobe University Graduate School of Medicine, Kobe, Japan, 2Department of Hospital Pharmacy, School of Medicine, Kobe University, Kobe, Japan, 3Department of Clinical Evaluation of Pharmacotherapy, Kobe University Graduate School of Medicine, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 194-200, 2006.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Activities of Rat Cytochrome P450 3A and 2C Isoforms are Increased In Vivo by Magnesium Sulfate as Evidenced by Enhanced Oxidation of Bupivacaine and Testosterone in Liver Microsomes
Miwako SAITO1, Toshiyuki OKUTOMI1, Makiko SHIMIZU2, Yoshiaki MATSUMOTO3, Hiroshi YAMAZAKI2, Sumio HOKA1
1Department of Anesthesiology, Kitasato University School of Medicine, Sagamihara, Japan, 2Showa Pharmaceutical University, Tokyo, Japan, 3College of Pharmacy, Nihon University, Funabashi, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 201-207, 2006.
1Department of Anesthesiology, Kitasato University School of Medicine, Sagamihara, Japan, 2Showa Pharmaceutical University, Tokyo, Japan, 3College of Pharmacy, Nihon University, Funabashi, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 201-207, 2006.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Sequence-based Analysis of the CYP2D6*36-CYP2D6*10 Tandem-type Arrangement, a Major CYP2D6*10 Haplotype in the Japanese Population
Akiko SOYAMA1, Yoshiro SAITO1, 2, Takashi KUBO1, Atsuko MIYAJIMA1, 3, Yasuo OHN03, Kazuo KOMAMURA4, 5, Kazuyuki UEN06, Shiro KAMAKURA4, Masafumi KITAKAZE4, Hitonobu TOMOIKE4, Shogo OZAWA1, 3, Jun-ichi SAWADA1, 2
1Project Team for Pharmacogenetics, National Institute of Health Sciences, Tokyo, Japan, 2Division of Biochemistry and Immunochemistry, National Institute of Health Sciences, Tokyo, Japan, 3Division of Pharmacology, National Institute of Health Sciences, Tokyo, Japan, 4Department of Cardiology, National Cardiovascular Center, Osaka, Japan, 5Department of Cardiovascular Dynamics Research Institute, National Cardiovascular Center, Osaka, Japan, 6Department of Pharmacy, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 208-216, 2006.
1Project Team for Pharmacogenetics, National Institute of Health Sciences, Tokyo, Japan, 2Division of Biochemistry and Immunochemistry, National Institute of Health Sciences, Tokyo, Japan, 3Division of Pharmacology, National Institute of Health Sciences, Tokyo, Japan, 4Department of Cardiology, National Cardiovascular Center, Osaka, Japan, 5Department of Cardiovascular Dynamics Research Institute, National Cardiovascular Center, Osaka, Japan, 6Department of Pharmacy, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 208-216, 2006.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
NaPi-mediated Transcellular Permeation is the Dominant Route in Intestinal Inorganic Phosphate Absorption in Rats
Nobuaki ETO1, Mikio TOMITA2, Masahiro HAYASHI2
1Pharmaceutical Research Laboratories, Kirin Brewery Co., Ltd, Gunma, Japan, 2Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 217-221, 2006.
1Pharmaceutical Research Laboratories, Kirin Brewery Co., Ltd, Gunma, Japan, 2Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 217-221, 2006.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Excellent Absorption Enhancing Characteristics of NO Donors for Improving the Intestinal Absorption of Poorly Absorbable Compound Compared with Conventional Absorption Enhancers
Gihan FETIH1, 2, Fawsia HABIB2, Hidemasa KATSUMI1, Naoki OKADA3, Takuya FUJITA1, Mohammed ATTIA2, Akira YAMAMOTO1
1Department of Biopharmaceutics, Kyoto Pharmaceutical University, Kyoto, Japan, 2Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt, 3Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 222-229, 2006.
1Department of Biopharmaceutics, Kyoto Pharmaceutical University, Kyoto, Japan, 2Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, Egypt, 3Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 222-229, 2006.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Ischemia/Reperfusion Injury in the Monolayers of Human Intestinal Epithelial Cell Line Caco-2 and Its Recovery by Antioxidants
Mayuko NAGIRA1, Mikio TOMITA1, Satoshi MIZUNO2, Miyuki KUMATA1, Toshiyuki AYABE1, Masahiro HAYASHI1
1Department of Drug Absorption and Pharmacokinetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, Japan, 2Kemin Japan Co. Ltd., Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 230-237, 2006.
1Department of Drug Absorption and Pharmacokinetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, Japan, 2Kemin Japan Co. Ltd., Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 230-237, 2006.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
What Kinds of Substrates Show P-Glycoprotein-Dependent Intestinal Absorption? Comparison of Verapamil with Vinblastine
Takuo OGIHARA1, Masatsugu KAMIYA1, Makoto OZAWA1, Takuya FUJITA2, Akira YAMAMOTO2, Shinji YAMASHITA3, Shuhei OHNISHI1, Yasuo ISOMURA1
1Pharmaceutical Research Center, Mochida Pharmaceutical Co., Ltd., Shizuoka, Japan, 2Department of Biopharmaceutics, Kyoto Pharmaceutical University, Kyoto, Japan, 3Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 238-244, 2006.
1Pharmaceutical Research Center, Mochida Pharmaceutical Co., Ltd., Shizuoka, Japan, 2Department of Biopharmaceutics, Kyoto Pharmaceutical University, Kyoto, Japan, 3Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 238-244, 2006.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Three Novel Single Nucleotide Polymorphisms of the FMO3 Gene in a Japanese Population
Makiko SHIMIZU, Haruka FUJITA, Takahiko AOYAMA, Hiroshi YAMAZAKI
Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 245-247, 2006.
Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 245-247, 2006.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Thirty Novel Genetic Variations in the SLC29A1 Gene Encoding Human Equilibrative Nucleoside Transporter 1 (hENT1)
Su-Ryang KIM1, Yoshiro SAITO1, 2, Keiko MAEKAWA1, 2, Emiko SUGIYAMA1, 3, Nahoko KANIWA1, 3, Hideki UENO4, Takuji OKUSAKA4, Chigusa MORIZANE4, Noboru YAMAMOTO5, Masafumi IKEDA4, Teruhiko YOSHIDA6, Hironobu MINAMI7, Junji FURUSE8, Hiroshi ISHII8, Nagahiro SAIJO9, Naoyuki KAMATANI10, Shogo OZAWA1, 11, Jun-ichi SAWADA1, 2
1Project Team for Pharmacogenetics, National Institute of Health Sciences, Tokyo, Japan, 2Division of Biochemistry and Immunochemistry, National Institute of Health Sciences, Tokyo, Japan, 3Division of Medicinal Safety Sciences, 4Division of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, 5Department of Medical Oncology, National Cancer Center Hospital, 6Genetics Division, National Cancer Center Research Institute, Tokyo, Japan, 7Oncology and Hematology Division, 8Division of Hapatobiliary and Pancreatic Oncology, 9Deputy Director, National Cancer Center Hospital East, Chiba, Japan, 10Division of Genomic Medicine, Department of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan, 11Division of Pharmacology, National Institute of Health Sciences, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 248-256, 2006.
1Project Team for Pharmacogenetics, National Institute of Health Sciences, Tokyo, Japan, 2Division of Biochemistry and Immunochemistry, National Institute of Health Sciences, Tokyo, Japan, 3Division of Medicinal Safety Sciences, 4Division of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, 5Department of Medical Oncology, National Cancer Center Hospital, 6Genetics Division, National Cancer Center Research Institute, Tokyo, Japan, 7Oncology and Hematology Division, 8Division of Hapatobiliary and Pancreatic Oncology, 9Deputy Director, National Cancer Center Hospital East, Chiba, Japan, 10Division of Genomic Medicine, Department of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan, 11Division of Pharmacology, National Institute of Health Sciences, Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 21 (3) 248-256, 2006.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
