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Update on Prediction of Drug Metabolizing Enzyme-and Transporter-based Drug Interactions
Kiyomi Ito1), Miki Nakajima2)
1)Musashino University, 2)Kanazawa University
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 1-2, 2010.
1)Musashino University, 2)Kanazawa University
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 1-2, 2010.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Drug Interaction Studies on New Drug Applications:Current Situations and Regulatory Views in Japan
Naomi NAGAI
Office of New Drug IV, Pharmaceuticals and Medical Devices Agency (PMDA)
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 3-15, 2010.
Office of New Drug IV, Pharmaceuticals and Medical Devices Agency (PMDA)
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 3-15, 2010.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
System-Dependent Outcomes during the Evaluation of Drug Candidates as Inhibitors of Cytochrome P450 (CYP) and Uridine Diphosphate Glucuronosyltransferase (UGT) Enzymes:Human Hepatocytes versus Liver Microsomes versus Recombinant Enzymes
Andrew PARKINSON*, Faraz KAZMI, David B.BUCKLEY, Phyllis YERINO, Brian W. OGILVIE, Brandy L.PARIS
XenoTech LLC
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 16-27, 2010.
XenoTech LLC
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 16-27, 2010.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Contribution of Intestinal Cytochrome P450-Mediated Metabolism to Drug-Drug Inhibition and Induction Interactions
Aleksandra GALETIN*, Michael GERTZ, J.Brian HOUSTON
School of Pharmacy and Pharmaceutical Sciences, University of Manchester
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 28-47, 2010.
School of Pharmacy and Pharmaceutical Sciences, University of Manchester
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 28-47, 2010.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Theoretical Considerations on Quantitative Prediction of Drug-Drug Interactions
Akihiro HISAKA1,*, Yoshiyuki OHNO2, Takehito YAMAMOTO2, Hiroshi SUZUKI2
1Pharmacology and Pharmacokinetics, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo, 2Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 48-61, 2010.
1Pharmacology and Pharmacokinetics, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo, 2Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 48-61, 2010.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Ongoing Challenges in Drug Interaction Safety:from Exposure to Pharmacogenomics
Jane P.F.BAI
Office of Clinical Pharmacology, Office of Translational Science, Center for Drug Evaluation and Research, US Food and Drug Administration
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 62-71, 2010.
Office of Clinical Pharmacology, Office of Translational Science, Center for Drug Evaluation and Research, US Food and Drug Administration
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 62-71, 2010.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Emerging New Technology:QSAR Analysis and MO Calculation to Characterize Interactions of Protein Kinase Inhibitors with the Human ABC Transporter, ABCG2 (BCRP)
Hikaru SAITO1,2, Ran AN1, Hiroyuki HIRANO1, Toshihisa ISHIKAWA1,3,*
1Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 2Department of Basic Medical Sciences, The institute of Medical Science, The University of Tokyo, 3Omics Science Center, RIKEN Yokohama Institute
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 72-83, 2010.
1Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 2Department of Basic Medical Sciences, The institute of Medical Science, The University of Tokyo, 3Omics Science Center, RIKEN Yokohama Institute
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 72-83, 2010.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
LKM-1 Sera from Autoimmune Hepatitis Patients that Recognize ERp57, Carboxylesterase 1 and CYP2D6
Ryo KOMURASAKI1, Susumu IMAOKA1,2,*, Naomichi TADA1, Kazushi OKADA1,2, Shuhei NISHIGUCHI3,4, Yoshihiko FUNAE2
1Nanobiotechnology Research Center and Department of Bioscience, School of Science and Technology, Kwansei Gakuin University, 2Department of Chemical Biology, Osaka City University Medical School, 3Department of Hepatology, Osaka City University Medical School, 4Division of Hepatobiliary and Pancreatic Diseases, Department of Internal Medicine, Hyogo College of Medicine
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 84-92, 2010.
1Nanobiotechnology Research Center and Department of Bioscience, School of Science and Technology, Kwansei Gakuin University, 2Department of Chemical Biology, Osaka City University Medical School, 3Department of Hepatology, Osaka City University Medical School, 4Division of Hepatobiliary and Pancreatic Diseases, Department of Internal Medicine, Hyogo College of Medicine
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 84-92, 2010.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Species Differences in Mechanism-Based Inactivation of CYP3A in Humans, Rats and Mice
Sasitorn AUEVIRIYAVIT, Kaoru KOBAYASHI*, Kan CHIBA
Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 93-100, 2010.
Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 93-100, 2010.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Receptor-Mediated Uptake of Human α1-Acid Glycoprotein into Liver Parenchymal Cells in Mice
Kazuaki MATSUMOTO1, Koji NISHI1,2, Mari KIKUCHI1, Hiroshi WATANABE1,3, Keisuke NAKAJOU1, Hisakazu KOMORI1, Daisuke KADOWAKI3, Ayaka SUENAGA1, Toru MARUYAMA1,3, Masaki OTAGIRI1,4,*
1Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 2Department of Clinical Pharmacy, Yokohama College of Pharmacy, 3Center for Clinical Pharmaceutical Sciences, Kumamoto University, 4Faculty of Pharmaceutical Sciences, Sojo University
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 101-107, 2010.
1Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 2Department of Clinical Pharmacy, Yokohama College of Pharmacy, 3Center for Clinical Pharmaceutical Sciences, Kumamoto University, 4Faculty of Pharmaceutical Sciences, Sojo University
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 101-107, 2010.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Peroxisome Proliferator-activated Receptor Alpha (PPARα) Agonists Induce Constitutive Androstane Receptor (CAR) and Cytochrome P450 2B in Rat Primary Hepatocytes
Kosuke SAITO, Kaoru KOBAYASHI*, Yuki MIZUNO, Yukina FUKUCHI, Tomomi FURIHATA, Kan CHIBA
Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 108-111, 2010.
Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 108-111, 2010.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Genetic Variations of the SLC22A5 Gene in the Chinese and Indian Populations of Singapore
Dorothy Su Lin TOH1,2, Jie Yin YEE1, Seok Hwee KOO1, Michael MURRAY2, Edmund Jon Deoon LEE1,*
1Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 2Faculty of Pharmacy, the University of Sydney
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 112-119, 2010.
1Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 2Faculty of Pharmacy, the University of Sydney
DRUG METABOLISM AND PHARMACOKINETICS 25 (1) 112-119, 2010.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
