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Diet-induced Lipid Accumulation in Liver Enhances ATP-binding Cassette Transporter g5/g8 Expression in Bile Canaliculi
Yasuhiro YAMAZAKI1, Takahiro HASHIZUME1, Hiroko MORIOKA1, Satoshi SADAMITSU1, Akira IKARI1, Masao MIWA1, Junko SUGATANI1,2
1Department of Pharmaco-Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 2Global Center of Excellence for Innovation in Human Health Sciences, School of Pharmaceutical Sciences, University of Shizuoka
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 442-450, 2011.
1Department of Pharmaco-Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, 2Global Center of Excellence for Innovation in Human Health Sciences, School of Pharmaceutical Sciences, University of Shizuoka
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 442-450, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Human Cytochrome P450 1A1 Is a Novel Target Gene of Liver X Receptor α
Norihito SHIBAHARA, Yuiko MASUNAGA, Shunsuke IWANO, Hiroshi YAMAZAKI, Kazuma KIYOTANI, Tetsuya KAMATAKI
Laboratory of Drug Metabolism, Graduate School of Pharmaceutical Sciences, Hokkaido University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 451-457, 2011.
Laboratory of Drug Metabolism, Graduate School of Pharmaceutical Sciences, Hokkaido University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 451-457, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Absence of Excretion of the Active Moiety of Bisacodyl and Sodium Picosulfate into Human Breast Milk: an Open-label, Parallel-group, Multiple-dose Study in Healthy Lactating Women
Christian FRIEDRICH1, Erika RICHTER2, Dirk TROMMESHAUSER3, Sandra DE KRUIF4, Thijs VAN IERSEL5, Ken MANDEL6, Ulrika GESSNER7
1Translational Medicine, Boehringer Ingelheim Pharma GmbH & Co. KG, 2Medical Data Services, Boehringer Ingelheim Pharma GmbH & Co. KG, 3Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim GmbH & Co. KG, 4Medical Department, Boehringer Ingelheim BV, 5Xendo Drug Development BV, 6KGM Innovation Associates, Inc., 7Consumer Health Care Mature Markets, DMRA, Boehringer Ingelheim Pharma GmbH & Co. KG
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 458-464, 2011.
1Translational Medicine, Boehringer Ingelheim Pharma GmbH & Co. KG, 2Medical Data Services, Boehringer Ingelheim Pharma GmbH & Co. KG, 3Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim GmbH & Co. KG, 4Medical Department, Boehringer Ingelheim BV, 5Xendo Drug Development BV, 6KGM Innovation Associates, Inc., 7Consumer Health Care Mature Markets, DMRA, Boehringer Ingelheim Pharma GmbH & Co. KG
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 458-464, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Correlation of Intrinsic in vitro and in vivo Clearance for Drugs Metabolized by Hepatic UDP-glucuronosyltransferases in Rats
Fumihiro NAKAMORI1,4, Yoichi NARITOMI1, Masako FURUTANI1, Fujiko TAKAMURA2, Hiroya MIURA3, Hidetsugu MURAI1, Shigeyuki TERASHITA1, Toshio TERAMURA1
1Analysis and Pharmacokinetics Research Labs, Discovery Drug Metabolism and Pharmacokinetics, Astellas Pharma Inc., 2Drug Metabolism Research Laboratories, Astellas Pharma Inc., 3Japanese Red Cross Plasma Fraction Center, 4Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 465-473, 2011.
1Analysis and Pharmacokinetics Research Labs, Discovery Drug Metabolism and Pharmacokinetics, Astellas Pharma Inc., 2Drug Metabolism Research Laboratories, Astellas Pharma Inc., 3Japanese Red Cross Plasma Fraction Center, 4Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 465-473, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Megalin/Cubilin-mediated Uptake of FITC-labeled IgG by OK Kidney Epithelial Cells
Junya NAGAI, Koya SATO, Ryoko YUMOTO, Mikihisa TAKANO
Department of Pharmaceutics and Therapeutics, Graduate School of Biomedical Sciences, Hiroshima University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 474-485, 2011.
Department of Pharmaceutics and Therapeutics, Graduate School of Biomedical Sciences, Hiroshima University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 474-485, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Inhibitory Effect of Caffeic Acid on Human Organic Anion Transporters hOAT1 and hOAT3: A Novel Candidate for Food-Drug Interaction
Yuichi UWAI, Yukihiro OZEKI, Tomonori ISAKA, Hiroaki HONJO, Kikuo IWAMOTO
Laboratory of Clinical Pharmacodynamics, School of Pharmacy, Aichi Gakuin University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 486-493, 2011.
Laboratory of Clinical Pharmacodynamics, School of Pharmacy, Aichi Gakuin University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 486-493, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Inhibitory Effect of Zinc on the Absorption of JBP485 via the Gastrointestinal Oligopeptide Transporter (PEPT1) in Rats
Qi MIAO1, Qi LIU1,3, Changyuan WANG1,3, Qiang MENG1,3, Xinjin GUO1, Jinyong PENG1,3, Taiichi KAKU2, Kexin LIU1,3
1Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, 2Japan Bioproducts Industry Co. Ltd., 3Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning, Dalian Medical University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 494-502, 2011.
1Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, 2Japan Bioproducts Industry Co. Ltd., 3Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning, Dalian Medical University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 494-502, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Chronopharmacological Assessment Identified GLUT4 as a Factor Responsible for the Circadian Variation of the Hypoglycemic Effect of Tolbutamide in Rats
Makoto MIYAZAKI, Toshiki FUJII, Nobuhiro TAKEDA, Hiroaki MAGOTANI, Kazunori IWANAGA, Masawo KAKEMI
Division of Pharmaceutics, Osaka University of Pharmaceutical Sciences
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 503-515, 2011.
Division of Pharmaceutics, Osaka University of Pharmaceutical Sciences
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 503-515, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Association between Cancer Risk and Drug-metabolizing Enzyme Gene (CYP2A6, CYP2A13, CYP4B1, SULT1A1, GSTM1, and GSTT1) Polymorphisms in Cases of Lung Cancer in Japan
Yuichiro TAMAKI1, Tomio ARAI2, Haruhiko SUGIMURA3, Takamitsu SASAKI4, Masashi HONDA1, Yuka MUROI1, Yoichi MATSUBARA5, Shuichi KANNO6, Masaaki ISHIKAWA6, Noriyasu HIRASAWA1, Masahiro HIRATSUKA1
1Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, 2Department of Pathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 3First Department of Pathology, Hamamatsu University School of Medicine, 4Department of Environmental and Health Science, Tohoku Pharmaceutical University, 5Department of Medical Genetics, Tohoku University School of Medicine, 6Department of Clinical Pharmacotherapeutics, Tohoku Pharmaceutical University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 516-522, 2011.
1Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, 2Department of Pathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 3First Department of Pathology, Hamamatsu University School of Medicine, 4Department of Environmental and Health Science, Tohoku Pharmaceutical University, 5Department of Medical Genetics, Tohoku University School of Medicine, 6Department of Clinical Pharmacotherapeutics, Tohoku Pharmaceutical University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 516-522, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Optimal Dosage Regimen of Meropenem for Pediatric Patients Based on Pharmacokinetic/Pharmacodynamic Considerations
Yuka OHATA1, Yoshiko TOMITA1, Mitsunobu NAKAYAMA1, Tsuneo KOZUKI1,2, Keisuke SUNAKAWA3, Yusuke TANIGAWARA4
1Drug Development Division, Dainippon Sumitomo Pharma Co., Ltd, 2Sales and Marketing Division, Dainippon Sumitomo Pharma Co., Ltd, 3Kitasato Institute for Life Science and Graduate School of Infection Control Science, Kitasato University, 4Department of Clinical Pharmacokinetics and Pharmacodynamics, School of Medicine, Keio University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 523-531, 2011.
1Drug Development Division, Dainippon Sumitomo Pharma Co., Ltd, 2Sales and Marketing Division, Dainippon Sumitomo Pharma Co., Ltd, 3Kitasato Institute for Life Science and Graduate School of Infection Control Science, Kitasato University, 4Department of Clinical Pharmacokinetics and Pharmacodynamics, School of Medicine, Keio University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 523-531, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Individual Differences in Pharmacokinetics and Pharmacodynamics of Anesthetic Agent Propofol with Regard to CYP2B6 and UGT1A9 Genotype and Patient Age
Fumiyasu KANSAKU1, Toshio KUMAI2, Kuniharu SASAKI1, Makito YOKOZUKA2, Makiko SHIMIZU1, Tadashi TATEDA2, Norie MURAYAMA1, Shinichi KOBAYASHI2, Hiroshi YAMAZAKI1
1Showa Pharmaceutical University, 2St. Marianna University School of Medicine
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 532-537, 2011.
1Showa Pharmaceutical University, 2St. Marianna University School of Medicine
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 532-537, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Effect of Genetic Polymorphisms of SLC28A1, ABCG2, and ABCC4 on Bioavailability of Mizoribine in Healthy Japanese Males
Miki FUKAO1, Kazuya ISHIDA1, Takuya SAKAMOTO1, Masato TAGUCHI1, Hiroyoshi MATSUKURA2, Toshio MIYAWAKI1, Yukiya HASHIMOTO1
1Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2Department of Pediatrics, Saiseikai Toyama Hospital
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 538-543, 2011.
1Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2Department of Pediatrics, Saiseikai Toyama Hospital
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 538-543, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Novel Single Nucleotide Polymorphism of the CYP2A13 Gene in Japanese Individuals
Yuichiro TAMAKI1, Masashi HONDA1, Yuka MUROI1, Tomio ARAI2, Haruhiko SUGIMURA3, Yoichi MATSUBARA4, Shuichi KANNO5, Masaaki ISHIKAWA5, Noriyasu HIRASAWA1, Masahiro HIRATSUKA1
1Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, 2Department of Pathology, Tokyo Metropolitan Geriatric Hospital, 3Department of Pathology I, Hamamatsu University School of Medicine, 4Department of Medical Genetics, Tohoku University School of Medicine, 5Department of Clinical Pharmacotherapeutics, Tohoku Pharmaceutical University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 544-547, 2011.
1Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, 2Department of Pathology, Tokyo Metropolitan Geriatric Hospital, 3Department of Pathology I, Hamamatsu University School of Medicine, 4Department of Medical Genetics, Tohoku University School of Medicine, 5Department of Clinical Pharmacotherapeutics, Tohoku Pharmaceutical University
DRUG METABOLISM AND PHARMACOKINETICS 26 (5) 544-547, 2011.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
