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DRUG METABOLISM AND PHARMACOKINETICS 27巻 4号

発行元
日本薬物動態学会
ISSN
1347-4367
ISSN(オンライン)
1880-0920
前雑誌
薬物動態

書籍情報から探す
開始頁
A "White Knight" Role for DMPK Researchers in Pharmaceutical Discovery: Maximization of Biomarker and Translational M&S Activities
Toshio TERAMURA
Astellas Pharma Incorporation
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 365-367, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Long-lasting Inhibitory Effects of Cyclosporin A, but Not Tacrolimus, on OATP1B1- and OATP1B3-mediated Uptake
Yoshihisa SHITARA1, Kumiko TAKEUCHI2, Yoshiko NAGAMATSU2, Satomi WADA2, Yuichi SUGIYAMA3, Toshiharu HORIE2
1Meiji Seika Pharma Co.,Ltd., 2Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, 3Department of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, University of Tokyo
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 368-378, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Physicochemical and Pharmacokinetic Characterization of Amorphous Solid Dispersion of Tranilast with Enhanced Solubility in Gastric Fluid and Improved Oral Bioavailability
Satomi ONOUE1, Yoshiki KOJO1, Yosuke AOKI1, Yohei KAWABATA1, Yukinori YAMAUCHI2, Shizuo YAMADA1
1Department of Pharmacokinetics and Pharmacodynamics and Global Center of Excellence (COE) Program, School of Pharmaceutical Sciences, University of Shizuoka, 2Department of Pharmaceutical Physical Chemistry, College of Pharmaceutical Sciences, Matsuyama University
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 379-387, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
The Effects of N-Glycosylation on the Glucuronidation of Zidovudine and Morphine by UGT2B7 Expressed in HEK293 Cells
Kenjiro NAGAOKA1, Nobumitsu HANIOKA1, Shinichi IKUSHIRO2, Shigeru YAMANO3, Shizuo NARIMATSU1
1Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2Faculty of Engineering, Toyama Prefectural University, 3Faculty of Pharmaceutical Sciences, Fukuoka University
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 388-397, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Effects of Hypoxia-inducible Factor-1α Chemical Stabilizer, CoCl2 and Hypoxia on Gene Expression of CYP3As in Human Fetal Liver Cells
Eiji SUZUKI1,2, Tamihide MATSUNAGA3, Akiko AONUMA1,4, Takamitsu SASAKI5, Kiyoshi NAGATA5, Shigeru OHMORI1,4
1Department of Molecular Pharmacology, Shinshu University Graduate School of Medicine, 2Department of Pharmacy, Nagano Municipal Hospital, 3Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, 4Department of Pharmacy, Shinshu University Hospital, 5Department of Environmental and Health Science, Tohoku Pharmaceutical University
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 398-404, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Inter-individual Variability of In Vivo CYP2D6 Activity in Different Genotypes
Koji CHIBA1, Motohiro KATO2, Takashi ITO3, Toshio SUWA1, Yuichi SUGIYAMA4
1Keio University, 2Chugai Pharmaceutical Co.Ltd., 3Daiichi Sankyo Co.Ltd., 4The University of Tokyo
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 405-413, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Impact of CYP3A5 and ABCB1 Gene Polymorphisms on Fentanyl Pharmacokinetics and Clinical Responses in Cancer Patients Undergoing Conversion to a Transdermal System
Yoshiaki TAKASHINA1, Takafumi NAITO1, Yasuaki MINO1, Tatsuya YAGI1, Kazunori OHNISHI2, Junichi KAWAKAMI1
1Department of Hospital Pharmacy, Hamamatsu University School of Medicine, 2Oncology Center, Hamamatsu University School of Medicine
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 414-421, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Pharmacokinetics of the H2 Blocker Roxatidine Acetate Hydrochloride in Pediatric Patients, in Comparison with Healthy Adult Volunteers
Hidefumi NAKAMURA1, Hisashi KAWASHIMA2, Rieko AZUMA3, Ikuya SATO3, Koji NAGAO3, Katsuhiko MIYAZAWA3
1National Center for Child Health and Development, 2Tokyo Medical University, 3Clinical Development Center, ASKA Pharmaceutical Co.,Ltd.
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 422-429, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Lower Expression of HNF4α and PGC1α Might Impair Rifampicin-mediated CYP3A4 Induction under Conditions Where PXR Is Overexpressed in Human Fetal Liver Cells
Takashi TAKEZAWA1, Tamihide MATSUNAGA2, Kaori AIKAWA1, Katsunori NAKAMURA1, Shigeru OHMORI1
1Department of Pharmacy, Shinshu University Hospital, 2Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 430-438, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Mechanism of Nucleoside Uptake in Rat Placenta and Induction of Placental CNT2 in Experimental Diabetes
Tomohiro NISHIMURA1, Takuya CHISHU1, Masatoshi TOMI1, Ryo NAKAMURA1, Kazuko SATO1, Noriko KOSE1, Yoshimichi SAI1,2, Emi NAKASHIMA1
1Faculty of Pharmacy, Keio University, 2Department of Pharmacy, Kanazawa University Hospital
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 439-446, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Development of a Rapid and Inexpensive Assay for Detecting a Surrogate Genetic Polymorphism of HLA-B*58:01: A Partially Predictive but Useful Biomarker for Allopurinol-related Stevens-Johnson Syndrome/toxic Epidermal Necrolysis in Japanese
Keiko MAEKAWA1, Jun NISHIKAWA1, Nahoko KANIWA1, Emiko SUGIYAMA1, Tomoko KOIZUMI1, Kouichi KUROSE1, Masahiro TOHKIN2, Yoshiro SAITO1
1Division of Medicinal Safety Science, National Institute of Health Sciences, 2Department of Medicinal Safety Science, Graduate School of Pharmaceutical Sciences, Nagoya City University
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 447-450, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Expression Profile of Early Estradiol-responsive Genes in Cynomolgus Macaque Liver: Implications for Drug-metabolizing Enzymes
Ryota ISE1, Go KITO2, Yasuhiro UNO2,3
1Drug Safety Research Center, Shin Nippon Biomedical Laboratories, Ltd., 2Laboratory of Translational Research, Graduate School of Pharmaceutical Sciences, Hokkaido University, 3Pharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd.
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 451-455, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Genetic Variations of the MCT4 (SLC16A3) Gene in the Chinese and Indian Populations of Singapore
Choo Bee LEAN, Edmund Jon Deoon LEE
Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore
DRUG METABOLISM AND PHARMACOKINETICS 27 (4) 456-464, 2012.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。