バックナンバー:DRUG METABOLISM AND PHARMACOKINETICS

DRUG METABOLISM AND PHARMACOKINETICS
29巻 2号

  • Drug-induced Liver Toxicity Studies:Research into Human Metabolites Clarifies Their Role in Drug Development

    Hiroshi YAMAZAKI
    Drug Metabolism and Pharmacokinetics Showa Pharmaceutical University
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 111-111, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Differences in the Glucuronidation of Resveratrol and Pterostilbene: Altered Enzyme Specificity and Potential Gender Differences

    Ryan W.DELLINGER1,2,3, Angela M.Gomez GARCIA1,2, Frank L.MEYSKENS, Jr.1,2,4,5
    1Chao Family Comprehensive Cancer Center, Department of Medicine, University of California Irvine, 2Department of Medicine, University of California Irvine, 3Department of Epidemiology, University of California Irvine, 4Department of Biological Chemistry, University of California Irvine, 5Department of Public Health, University of California Irvine
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 112-119, 2014.


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  • Development of a Pharmacokinetic Interaction Model for Co-administration of Simvastatin and Amlodipine

    Hankil SON1,2, Donghwan LEE1,2, Lay Ahyoung LIM1,2, Seong Bok JANG3, Hyerang ROH1,2, Kyungsoo PARK1,2
    1Department of Pharmacology, Yonsei University College of Medicine, 2Brain Korea 21 Project for Medical Science, Yonsei University, 3Department of Clinical Development, Yuhan Corporation
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 120-128, 2014.


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  • Glucuronidation and Subsequent Biliary Excretion of Mycophenolic Acid in Rat Sandwich-cultured Hepatocytes

    Kazuhiro TETSUKA, Nicolas GERST, Kouichi TAMURA, Jeffrey N.MASTERS
    Astellas Research Institute of America LLC
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 129-134, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Identification and Characterization of Human UDP-glucuronosyltransferases Responsible for the Glucuronidation of Fraxetin

    Yang-Liu XIA1,2, Si-Cheng LIANG1,2, Liang-Liang ZHU1, Guang-Bo GE1, Gui-Yuan HE1,2, Jing NING1, Xia LV1, Xiao-Chi MA3, Ling YANG1, Sheng-Li YANG1
    1Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 2Graduate University of Chinese Academy of Sciences, 3Dalian Medical University
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 135-140, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Single-dose Pharmacokinetics of the HCV Polymerase Inhibitor Mericitabine in Healthy Caucasian and Japanese Subjects

    Carla WASHINGTON1, Sebastian MOREIRA2, Joshua HAZNEDAR1, Petra GOELZER2, Ya-Chi CHEN2
    1Genentech, South San Francisco, 2Hoffmann-La Roche Inc., Nutley
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 141-147, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Characteristics of Pemetrexed Transport by Renal Basolateral Organic Anion Transporter hOAT3

    Tomohiko KURATA1, Takuya IWAMOTO1,2, Yuki KAWAHARA1, Masahiro OKUDA1,2
    1Department of Clinical Pharmacy and Biopharmaceutics, Mie University Graduate School of Medicine, 2Department of Pharmacy, Mie University Hospital, Faculty of Medicine, Mie University
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 148-153, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Effects of Peritoneal Dialysis on Pharmacotherapy: A Deductive Pharmacokinetic-model Approach to Predict Drug Concentration Profiles in Plasma and Peritoneal Fluid

    Mizuki HORIUCHI, Soichiro MORIYAMA, Yukiko TAKAHATA, Tetsuya AIBA, Yuji KUROSAKI
    Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 154-161, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Variability of Bioavailability and Intestinal Absorption Mechanisms of Metoprolol

    Miki FUKAO, Kazuya ISHIDA, Asuka HORIE, Masato TAGUCHI, Takashi NOZAWA, Hiroshi INOUE, Yukiya HASHIMOTO
    Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 162-167, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Utility of Cryopreserved Hepatocytes Suspended in Serum to Predict Hepatic Clearance in Dogs and Monkeys

    Yoshihiro SHIBATA, Jiro KUZE, Masato CHIBA
    Discovery Drug Metabolism & Pharmacokinetics, Pharmacokinetics Research Laboratories, Tsukuba Research Center, Taiho Pharmaceutical Co.,Ltd.
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 168-176, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Deeper Insight into the Reducing Biotransformation of Bupropion in the Human Liver

    Lucie SKARYDOVA1, Radana TOMANOVA1, Lucie HAVLIKOVA2, Hana STAMBERGOVA1, Petr SOLICH2, Vladimir WSOL1
    1Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, 2Department of Analytical Chemistry, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 177-184, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
    全文ダウンロード(1.39MB)】 従量制、基本料金制の方共に660円(税込) です。

  • Assessing the Impact of HER2 Status on the Antitumor Activity of an HSP90 Inhibitor in Human Tumor Xenograft Mice Using Pharmacokinetic-Pharmacodynamic Modeling

    Ryoichi SAITOH, Miho NAGAYASU, Norihito SHIBAHARA, Naomi ONO, Atsushi SUDA, Motohiro KATO, Masaki ISHIGAI
    Research Division, Chugai Pharmaceutical Co.,Ltd.
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 185-191, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
    全文ダウンロード(2.23MB)】 従量制、基本料金制の方共に660円(税込) です。

  • Sex Differences in the Constitutive Gene Expression of Sulfotransferases and UDP-glucuronosyltransferases in the Pig Liver: Androgen-mediated Regulation

    Misaki KOJIMA1, Masakuni DEGAWA2
    1Animal Genome Research Unit, Agrogenomics Research Center, National Institute of Agrobiological Sciences, 2Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 192-197, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
    全文ダウンロード(1.59MB)】 従量制、基本料金制の方共に660円(税込) です。

  • Cocktail-substrate Approach-based High-throughput Assay for Evaluation of Direct and Time-dependent Inhibition of Multiple Cytochrome P450 Isoforms

    Kazumasa KOZAKAI1, Yasuhiro YAMADA1, Motoji OSHIKATA2, Taiji KAWASE2, Etsuko SUZUKI2, Yukari HARAMAKI2, Hideki TANIGUCHI1
    1Department of Regenerative Medicine, Yokohama City University School of Medicine, 2Solutions Center, Nihon Waters K.K.
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 198-207, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
    全文ダウンロード(1.96MB)】 従量制、基本料金制の方共に660円(税込) です。

  • A Common Variant of Organic Anion Transporter 4 (OAT4/SLC22A11) Gene Is Associated with Renal Underexcretion Type Gout

    Masayuki SAKIYAMA1,2, Hirotaka MATSUO1, Seiko SHIMIZU1, Hiroshi NAKASHIMA3, Akiyoshi NAKAYAMA1, Toshinori CHIBA1, Mariko NAITO4, Tappei TAKADA5, Hiroshi SUZUKI5, Nobuyuki HAMAJIMA6, Kimiyoshi ICHIDA7,8, Toru SHIMIZU9, Nariyoshi SHINOMIYA1
    1Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, 2Department of Dermatology, National Defense Medical College, 3Department of Preventive Medicine and Public Health, National Defense Medical College, 4Department of Preventive Medicine, Nagoya University Graduate School of Medicine, 5Department of Pharmacy, the University of Tokyo Hospital, Faculty of Medicine, the University of Tokyo, 6Department of Healthcare Administration, Nagoya University Graduate School of Medicine, 7Department of Pathophysiology, Tokyo University of Pharmacy and Life Sciences, 8Division of Kidney and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, 9Midorigaoka Hospital
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 208-210, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Functional Analysis of Purine Nucleoside Phosphorylase as a Key Enzyme in Ribavirin Metabolism

    Tomomi FURIHATA, Satoshi KISHIDA, Hanae SUGIURA, Atsuko KAMIICHI, Minami IIKURA, Kan CHIBA
    Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 211-214, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
    全文ダウンロード(0.92MB)】 従量制、基本料金制の方共に660円(税込) です。

  • Association of the CYP2B6 c.516G>T Polymorphism with High Blood Propofol Concentrations in Women from Northern Greece

    Orthodoxia MASTROGIANNI1, Emma GBANDI2, Amvrosios ORPHANIDIS1, Nikolaos RAIKOS1, Evangelia GOUTZIOMITROU3, Efstratios M. KOLIBIANAKIS3, Basil C. TARLATZIS3, Antonis GOULAS2
    1Department of Forensic Medicine and Toxicology, Medical School, Aristotle University of Thessaloniki, 2Department of Pharmacology, Medical School, Aristotle University of Thessaloniki, 3Unit for Human Reproduction, 1st Department of Obstetrics and Gynecology, Papageorgiou General Hospital, Medical School, Aristotle University of Thessaloniki
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 215-218, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Role of CYP3A in Isoniazid Metabolism In Vivo

    Ke LIU1, Feng LI2, Jie LU1, Zhiwei GAO3, Curtis D.KLAASSEN2, Xiaochao MA1
    1Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, 2Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, 3Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 219-222, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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  • Involvement of AP-1 and NF-кB in the Up-regulation of P-gp in Vinblastine Resistant Caco-2 Cells

    Qiuxia CHEN, Yicong BIAN, Su ZENG
    Laboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences
    DRUG METABOLISM AND PHARMACOKINETICS 29(2): 223-226, 2014.


    アブストラクト】 従量制は110円(税込)、基本料金制は基本料金に含まれます
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book
発行元:
日本薬物動態学会
ISSN:
1347-4367
ISSN(オンライン):
1880-0920
前雑誌:
薬物動態

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Medical Online English Site