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Perspective of Humanized Mouse Models for Assessing PK/PD and Toxic Profile of Drug Candidates in Preclinical Study
Kan CHIBA
JSSX, Graduate School of Pharmaceutical Sciences, Chiba University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 1-2, 2014.
JSSX, Graduate School of Pharmaceutical Sciences, Chiba University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 1-2, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
The Cutting-edge of Clinical Therapeutics Based on Pharmacokinetic/Pharmacodynamic Theory
Ken-ichi HOSOYA1), Katsuhisa INOUE2)
1)Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2)School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 3-3, 2014.
1)Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2)School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 3-3, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Optimization of Mycophenolic Acid Therapy Using Clinical Pharmacometrics
Min DONG1), Tsuyoshi FUKUDA1),2), Alexander A.VINKS1),2)
1)Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, 2)Department of Pediatrics, University of Cincinnati College of Medicine
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 4-11, 2014.
1)Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, 2)Department of Pediatrics, University of Cincinnati College of Medicine
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 4-11, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Molecular Basis for Pharmacokinetics and Pharmacodynamics of Methotrexate in Rheumatoid Arthritis Therapy
Katsuhisa INOUE1), Hiroaki YUASA2)
1)Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 2)Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Nagoya City University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 12-19, 2014.
1)Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 2)Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Nagoya City University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 12-19, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Optimization of Cancer Chemotherapy on the Basis of Pharmacokinetics and Pharmacodynamics: From Patients Enrolled in Clinical Trials to Those in the 'Real World'
Ken-ichi FUJITA1), Yasutsuna SASAKI1),2)
1)Institute of Molecular Oncology, Showa University, 2)Division of Medical Oncology, Department of Medicine, Showa University School of Medicine
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 20-28, 2014.
1)Institute of Molecular Oncology, Showa University, 2)Division of Medical Oncology, Department of Medicine, Showa University School of Medicine
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 20-28, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Influence of Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Polymorphisms on Pain Sensitivity and Clinical Response to Weak Opioid Analgesics
Zalina ZAHARI1),2), Rusli ISMAIL2),3)
1)Department of Pharmacy, Hospital Universiti Sains Malaysia, 2)Pharmacogenetics and Novel Therapeutics Cluster, Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia (USM), 3)Centre of Excellence for Research in AIDS (CERiA), University of Malaya
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 29-43, 2014.
1)Department of Pharmacy, Hospital Universiti Sains Malaysia, 2)Pharmacogenetics and Novel Therapeutics Cluster, Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia (USM), 3)Centre of Excellence for Research in AIDS (CERiA), University of Malaya
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 29-43, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Differentiation of Human Induced Pluripotent Stem Cells into Functional Enterocyte-like Cells Using a Simple Method
Takahiro IWAO1), Masashi TOYOTA2), Yoshitaka MIYAGAWA3), Hajime OKITA3), Nobutaka KIYOKAWA3), Hidenori AKUTSU2), Akihiro UMEZAWA2), Kiyoshi NAGATA4), Tamihide MATSUNAGA1)
1)Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, 2)Department of Reproductive Biology, National Research Institute for Child Health and Development, 3)Department of Hematology and Oncology Research, National Research Institute for Child Health and Development, 4)Department of Environmental and Health Science, Tohoku Pharmaceutical University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 44-51, 2014.
1)Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University, 2)Department of Reproductive Biology, National Research Institute for Child Health and Development, 3)Department of Hematology and Oncology Research, National Research Institute for Child Health and Development, 4)Department of Environmental and Health Science, Tohoku Pharmaceutical University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 44-51, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
In Silico Study on the Inhibitory Interaction of Drugs with Wild-type CYP2D6.1 and the Natural Variant CYP2D6.17
Koichi HANDA1),2), Izumi NAKAGOME1), Noriyuki YAMAOTSU1), Hiroaki GOUDA1),3), Shuichi HIRONO1)
1)School of Pharmacy, Kitasato University, 2)Research Laboratories, Toyama Chemical Co.,Ltd., 3)School of Pharmacy, Showa University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 52-60, 2014.
1)School of Pharmacy, Kitasato University, 2)Research Laboratories, Toyama Chemical Co.,Ltd., 3)School of Pharmacy, Showa University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 52-60, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Development of an Integrated Population Pharmacokinetic Model for Oral Levetiracetam in Populations of Various Ages and Ethnicities
Nathalie TOUBLANC1), Brigitte D.LACROIX1), Junichi YAMAMOTO2)
1)Modeling and Simulation, GED, UCB Pharma, 2)Clinical Pharmacology, UCB Pharma
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 61-68, 2014.
1)Modeling and Simulation, GED, UCB Pharma, 2)Clinical Pharmacology, UCB Pharma
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 61-68, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Functional Expression of Organic Cation/carnitine Transporter 2 (OCTN2/SLC22A5) in Human Brain Capillary Endothelial Cell Line hCMEC/D3, a Human Blood-brain Barrier Model
Takashi OKURA, Sayaka KATO, Yoshiharu DEGUCHI
Laboratory of Drug Disposition & Pharmacokinetics, Faculty of Pharma-Sciences, Teikyo University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 69-74, 2014.
Laboratory of Drug Disposition & Pharmacokinetics, Faculty of Pharma-Sciences, Teikyo University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 69-74, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Mechanism-based Inactivation of Cytochrome P450 2A6 and 2A13 by Rhinacanthus nasutus Constituents
Phisit POUYFUNG1), Aruna PRASOPTHUM1), Songklod SARAPUSIT2), Ekaruth SRISOOK3),4), Pornpimol RONGNOPARUT1)
1)Department of Biochemistry, Faculty of Science, Mahidol University, 2)Department of Biochemistry, Faculty of Science, Burapha University, 3)Department of Chemistry, Faculty of Science, Burapha University, 4)Center for Innovation in Chemistry, Burapha University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 75-82, 2014.
1)Department of Biochemistry, Faculty of Science, Mahidol University, 2)Department of Biochemistry, Faculty of Science, Burapha University, 3)Department of Chemistry, Faculty of Science, Burapha University, 4)Center for Innovation in Chemistry, Burapha University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 75-82, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Association between CYP3A5 Genotypes in Graft Liver and Increase in Tacrolimus Biotransformation from Steroid Treatment in Living-donor Liver Transplant Patients
Keiko HOSOHATA1), Miwa UESUGI1), Sachiyo HASHI1), Mio HOSOKAWA1), Ken-ichi INUI1), Kazuo MATSUBARA1), Kohei OGAWA2), Yasuhiro FUJIMOTO2), Toshimi KAIDO2), Shinji UEMOTO2), Satohiro MASUDA1)
1)Department of Pharmacy, Faculty of Medicine, Kyoto University Hospital, 2)Division of Hepatobiliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 83-89, 2014.
1)Department of Pharmacy, Faculty of Medicine, Kyoto University Hospital, 2)Division of Hepatobiliary-Pancreatic Surgery and Transplantation, Department of Surgery, Graduate School of Medicine, Kyoto University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 83-89, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Comparative Studies of Human UDP-glucuronosyltransferase 1A8 and 1A9 Proximal Promoters Using Single Base Substitutions
Zhang XIAO1), Kana NUNOME2), Taemi YAHARA2), Emi INOUE2), Masakazu NABESHIMA2), Shirou TSUCHIDA2), Naoya HAMAUE2), Takashi AOKI2)
1)Department of Biochemistry and Molecular Biology, Medical College of Qingdao University, 2)Department of Molecular Biosciences, School of Pharmaceutical Sciences, Health Sciences University of Hokkaido
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 90-93, 2014.
1)Department of Biochemistry and Molecular Biology, Medical College of Qingdao University, 2)Department of Molecular Biosciences, School of Pharmaceutical Sciences, Health Sciences University of Hokkaido
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 90-93, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
More Relevant Prediction for In Vivo Drug Interaction of Candesartan Cilexetil on Hepatic Bile Acid Transporter BSEP Using Sandwich-cultured Hepatocytes
Hajime FUKUDA, Takeo NAKANISHI, Ikumi TAMAI
Department of Membrane Transport and Biopharmaceutics, Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 94-96, 2014.
Department of Membrane Transport and Biopharmaceutics, Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 94-96, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Pharmacokinetics of Guanidinosuccinic Acid in Rat Blood and Cerebrospinal Fluid
Yasuyuki KASAI1), Shin-ichi AKANUMA1), Yoshiyuki KUBO1), Masanori TACHIKAWA2), Ken-ichi HOSOYA1)
1)Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2)Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 97-100, 2014.
1)Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2)Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 97-100, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
The Verapamil Transporter Expressed in Human Alveolar Epithelial Cells (A549) Does Not Interact with β2-Receptor Agonists
Johanna J.SALOMON1), Carsten EHRHARDT1),2), Ken-ichi HOSOYA3)
1)School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, 2)Trinity Biomedical Sciences Institute, Trinity College Dublin, 3)Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 101-104, 2014.
1)School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, 2)Trinity Biomedical Sciences Institute, Trinity College Dublin, 3)Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 101-104, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Genetic Variations in UDP-glucuronosyltransferase 2B15 in a Korean Population
Mi-Sun HWANG1), Su-Jun LEE1), Woo-Young KIM1), Hye-Eun JEONG1), Jae-Gook SHIN1),2)
1)Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Inje University, 2)Department of Clinical Pharmacology, Inje University Busan Paik Hospital, Inje University College of Medicine, Inje University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 105-109, 2014.
1)Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Inje University, 2)Department of Clinical Pharmacology, Inje University Busan Paik Hospital, Inje University College of Medicine, Inje University
DRUG METABOLISM AND PHARMACOKINETICS 29 (1) 105-109, 2014.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
