薬物動態 7巻 4号

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Suplatast tosilate(IPD-1151T)の体内動態(第1報)：14C-Suplatast tosilate(IPD-1151T)のラットにおける吸収,分布,排泄

桑田慶三*, 増田啓年*, 山本佳男*, 新藤恭司*, 重松昭世**, 羽山恵美子**, 泉二奈緒美**, 黒岩浩幸**, 河合直士**
*大鵬薬品工業株式会社開発研究所, **株式会社生体科学研究所
薬物動態 7 (4) 399-421, 1992.

Suplatast tosilate(IPD-1151T)の体内動態(第2報):Suplatast tosilate代謝物の同定と14C-Suplatast tosilateのラットでの代謝

増田啓年, 桑田慶三, 松島英司, 山脇一郎, 新藤恭司
大鵬薬品工業株式会社開発研究所
薬物動態 7 (4) 423-439, 1992.

Suplatast tosilate(IPD-1151T)の体内動態(第3報):Suplatast tosilate(IPD-1151T)の体内動態における動物種差と代謝経路

新藤恭司, 増田啓年, 桑田慶三, 山本佳男, 佐藤俊幸
大鵬薬品工業株式会社開発研究所
薬物動態 7 (4) 441-459, 1992.

Studies on the Metabolic Fate of Felodipine (V): Absorption, Distribution, Metabolism and Excretion after a Single Oral Administration to Dogs

Kazuo UNO*, Satoru YAMAGAMI*, Shigeru TABATA**, Shuji KONDO**, Yoshio ESUMI***, Matsuo TAKAICHI***, Yoshitaka JIN***, Hisako ISHIKAWA***, Sadao TSUJI***
*Pharmacokinetic Research Laboratory, CIBA-GEIGY (Japan) Limited, **Pharma Research Laboratories, Hoechst Japan Limited, ***Tokai Research Laboratories, Daiichi Pure Chemicals Co., Ltd.
Xenobiotic metabolism and disposition 7 (4) 461-476, 1992.

Studies on the Metabolic Fate of 3H-TJN-101 (I) Absorption, Distribution and Excretion following Single Oral Administration to Rats.

Yutaka MATSUZAKI*, Tamae MATSUZAKI*, Shuichi TAKEDA*, Hiromi SASAKI*, Masaki ABURADA*, Eikichi HOSOYA*, Tsutomu OYAMA*, Yukinobu IKEYA**, Hiroshi MITSUHASHI**, Yoshio ESUMI***, Yoshitaka JIN***, Hisako ISHIKAWA***, Tetsuyoshi YOKOSHIMA***
*Research Institute for Pharmacology, TSUMURA & Co., **Research Institute for Biology and Chemistry, TSUMURA & Co., ***Tokai Research Laboratories, Daiichi Pure Chemicals Co. , Ltd. ,
Xenobiotic metabolism and disposition 7 (4) 477-494, 1992.

Studies on the Metabolic Fate of 3H-TJN-101 (II): Transfer into the Fetus and Milk.

Yutaka MATSUZAKI*, Tamae MATSUZAKI*, Shuichi TAKEDA*, Hiromi SASAKI*, Masaki ABURADA*, Eikichi HOSOYA*, Tsutomu OYAMA*, Yoshio ESUMI**, Yoshitaka JIN**, Hisako ISHIKAWA**, Tetsuyoshi YOKOSHIMA**
*Research Institute for Pharmacology, TSUMURA & Co., **Tokai Research Laboratories, Daiichi Pure Chemicals Co. , Ltd. ,
Xenobiotic metabolism and disposition 7 (4) 495-507, 1992.

Studies on the Metabolic Fate of 3H-TJN-101(III): Absorption, Distribution and Excretion after Multiple Oral Administration to Rats.

Yutaka MATSUZAKI*, Tamae MATSUZAKI*, Shuichi TAKEDA*, Hiromi SASAKI*, Masaki ABURADA*, Eikichi HOSOYA, Tsutomu OYAMA*, Yoshio ESUMI**, Yoshitaka JIN**, Hisako ISHIKAWA**, Tetsuyoshi YOKOSHIMA**
*Research Institute for Pharmacology, TSUMURA & Co., **Tokai Research Laboratories, Daiichi Pure Chemical Co., Ltd.
Xenobiotic metabolism and disposition 7 (4) 509-518, 1992.

Studies on the Metabolic Fate of 3H-TJN-101(IV): Metabolism of TJN-101 in Rats.

Yutaka MATSUZAKI*, Tamae MATSUZAKI*, Shuichi TAKEDA*, Hiromi SASAKI*, Masaki ABURADA*, Eikichi HOSOYA*, Tsutomu OYAMA*, Yukinobu IKEYA**, Hiroshi MITSUHASHI**, Yoshio ESUMI***, Yoshitaka JIN***, Hisako ISHIKAWA***, Tetsuyoshi YOKOSHIMA***
*Research Institute for Pharmacology, TSUMURA & Co., **Research Institute for Biology and Chemistry, TSUMURA & Co., ***Tokai Research Laboratories, Daiichi Pure Chemical Co. , Ltd. ,
Xenobiotic metabolism and disposition 7 (4) 519-527, 1992.

バイオアベイラビリティの評価へのPopulationpharmacokineticsの手法の適用

鹿庭なほ子
国立衛生試験所
薬物動態 7 (4) 529-535, 1992.

薬物動態 7巻 4号

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