バックナンバー:Biological and Pharmaceutical Bulletin

Biological and Pharmaceutical Bulletin
34巻 5号

  • The Neuroprotection of Oxymatrine in Cerebral Ischemia/Reperfusion Is Related to Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2)-Mediated Antioxidant Response:Role of Nrf2 and Hemeoxygenase-1 Expression

    Min LI, Xiangjian ZHANG*, Lili CUI, Rui YANG, Lina WANG, Lingling LIU, Wei Du
    Department of Neurology, Second Hospital of Hebei Medical University
    Biological & Pharmaceutical Bulletin 34(5): 595-601, 2011.


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  • Inhibition of Akt (ser473) Phosphorylation and Rapamycin-Resistant Cell Growth by Knockdown of Mammalian Target of Rapamycin with Small Interfering RNA in Vascular Endothelial Growth Factor Receptor-1-Targeting Vector

    Hiroyuki KOIDEa, Tomohiro ASAIa, Keiichi FURUYAa, Takuma TSUZUKUa, Hiroki KATOa, Takehisa DEWAb, Mamoru NANGOb, Noriyuki MAEDAc, Naoto OKU*a
    aDepartment of Medical Biochemistry and Global COE Program, University of Shizuoka Graduate School of Pharmaceutical Sciences, bMaterials Science and Engineering, Nagoya Institute of Technology, cNippon Fine Chemical Co., Ltd.
    Biological & Pharmaceutical Bulletin 34(5): 602-608, 2011.


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  • Protective Effects of Glycyrrhizin against β2-Adrenergic Receptor Agonist-Induced Receptor Internalization and Cell Apoptosis

    Qian SHIa, Yuanyuan HOUa, Yang YANGb, Gang BAI*a
    aCollege of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, bCollege of Life Sciences, Nankai University
    Biological & Pharmaceutical Bulletin 34(5): 609-617, 2011.


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  • Inhibition of Reactive Oxygen Species/Extracellular Signal-Regulated Kinases Pathway by Pioglitazone Attenuates Advanced Glycation End Products-Induced Proliferation of Vascular Smooth Muscle Cells in Rats

    Xiaochen YUANa,b, Zhengang ZHANGa, Kaizheng GONGa, Pei ZHAOa, Jianhua QINa, Naifeng LIU*b
    aDepartment of Cardiology, Institute of Cardiovascular Disease of Southeast University, the First People's Hospital of Yangzhou, bDepartment of Cardiology, Institute of Cardiovascular Medicine of Southeast University, Zhongda Hospital of Southeast University
    Biological & Pharmaceutical Bulletin 34(5): 618-623, 2011.


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  • High-Frequency Genetic Contents Variations in Clinical Candida albicans Isolates

    Feng YANGa,#, Tian-Hua YANa,#, Elena RUSTCHENKOb, Ping-Hui GAOc, Yan WANGc, Lan YANc, Ying-Ying CAOc, Qiu-Juan WANGc, Hui JI*a, Yong-Bing CAO*c, Yuan-Ying JIANGc
    aDepartment of Pharmacology, School of Pharmacy, China Pharmaceutical University, bDepartment of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester Medical School, cDepartment of Pharmacology, School of Pharmacy, Second Military Medical University
    Biological & Pharmaceutical Bulletin 34(5): 624-631, 2011.


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  • Modulation of Iron-Uptake Systems by a Mutation of luxS Encoding an Autoinducer-2 Synthase in Vibrio vulnificus

    Choon Mee KIMa, Sung Heui SHIN*a,b
    aResearch Center for Resistant Cells, Chosun University Medical School, bDepartment of Microbiology, Chosun University Medical School
    Biological & Pharmaceutical Bulletin 34(5): 632-637, 2011.


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  • Antimicrobial Activity of Gel-Entrapped Catechins toward Oral Microorganisms

    Muneaki TAMURA*a,b, Hideo SAITOc, Kuniyoshi KIKUCHIa,b, Tomohiko ISHIGAMIc,d, Yoshio TOYAMAe, Masao TAKAMIf, Kuniyasu OCHIAIa,b
    aDepartment of Microbiology, Nihon University School of Dentistry, bDivision of Immunology and Pathobiology, Dental Research Center, Nihon University School of Dentistry, cDepartment of Partial Denture Prosthodontics, Nihon University School of Dentistry, dDivision of Clinical Research, Dental Research Center, Nihon University School of Dentistry, eMedical Nutrition Section, Nutrition Foods Department, Division of Research and Development, Research and Development Center, Meiji Dairies Corporation, fNutrition Evaluation, Product Development Section, Nutritional Marketing Department II, Nutritional Consolidated Marketing Division, Meiji Dairies Corporation
    Biological & Pharmaceutical Bulletin 34(5): 638-643, 2011.


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  • Berberine-Improved Visceral White Adipose Tissue Insulin Resistance Associated with Altered Sterol Regulatory Element-Binding Proteins, Liver X Receptors, and Peroxisome Proliferator-Activated Receptors Transcriptional Programs in Diabetic Hamsters

    Guo-Sheng LI*a,c, Xu-Han LIUb,c, Hua ZHUc, Lan HUANGc, Ya-Li LIUc, Chun-Mei MAc, Chuan QIN*c
    aDepartment of Pathology, First Affiliated Hospital of Dalian Medical University, bDepartment of Endocrinology, Dalian Municipal Central Hospital, cDepartment of Pathology, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC)
    Biological & Pharmaceutical Bulletin 34(5): 644-654, 2011.


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  • The Enantiomers of Etodolac, a Racemic Anti-inflammatory Agent, Play Different Roles in Efficacy and Gastrointestinal Safety

    Naoki INOUE*, Masaki NOGAWA, Sunao ITO, Koyuki TAJIMA, Sato KUME, Takashi KYOI
    Pharmacology Department, Discovery Research Laboratories, Nippon Shinyaku Co., Ltd.
    Biological & Pharmaceutical Bulletin 34(5): 655-659, 2011.


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  • Innovative Preparation of Curcumin for Improved Oral Bioavailability

    Hiroki SASAKIa, Yoichi SUNAGAWAb,c,d, Kenji TAKAHASHIa, Atsushi IMAIZUMIa, Hiroyuki FUKUDAa, Tadashi HASHIMOTOa, Hiromichi WADAb, Yasufumi KATANASAKAd, Hideaki KAKEYAe, Masatoshi FUJITAc, Koji HASEGAWAb, Tatsuya MORIMOTO*d
    aTHERAVALUES CORPORATION, bDivision of Translational Research, Kyoto Medical Center, National Hospital Organization, cDepartment of Human Health Sciences, Graduate School of Medicine, Kyoto University, dDivision of Molecular Medicine, School of Pharmaceutical Sciences, University of Shizuoka, eDepartment of System Chemotherapy and Molecular Sciences, Division of Bioinformatics and Chemical Genomics, Graduate School of Pharmaceutical Sciences, Kyoto University
    Biological & Pharmaceutical Bulletin 34(5): 660-665, 2011.


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  • Effect of Heat Exposure on Aminophylline-Induced Convulsions in Mice

    Rika OCHIa, Katsuya SUEMARU*b, Shinichi WATANABEb, Takumi YAMAGUCHIc, Kenshi TAKECHIa, Hiromu KAWASAKIa, Hiroaki ARAKIb
    aDepartment of Clinical Pharmaceutical Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, bDepartment of Clinical Pharmacology and Pharmacy, Ehime University Graduate School of Medicine, cDepartment of Clinical Pharmaceutical Science, Matsuyama University
    Biological & Pharmaceutical Bulletin 34(5): 666-670, 2011.


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  • Nateglinide Stimulates Glucagon-Like Peptide-1 Release by Human Intestinal L Cells via a KATP Channel-Independent Mechanism

    Yoshiro KITAHARA*, Kyoko MIURA, Reiko YASUDA, Haruka KAWANABE, Shimpei OGAWA, Yuzuru ETO
    Exploratory Research Laboratories, Ajinomoto Pharmaceuticals Co., Ltd.
    Biological & Pharmaceutical Bulletin 34(5): 671-676, 2011.


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  • Anticancer Activity of S-Allylmercapto-L-cysteine on Implanted Tumor of Human Gastric Cancer Cell

    Yongkyu LEE*a, Hejin KIMa, Jinhwa LEEb, Kyongtai KiMc,d
    aDepartment of Food and Biotechnology, Dongseo University, bDepartment of Clinical Laboratory Science, Dongseo University, cDepartment of Life Science, Division of Molecular and Life Science, Pohang University of Science and Technology, dDivision of Integrative Bioscience & Biotechnology, Pohang University of Science and Technology
    Biological & Pharmaceutical Bulletin 34(5): 677-681, 2011.


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  • Inhibitory Effects of Dexamethasone on Epidermal Growth Factor- Induced DNA Synthesis and Proliferation in Primary Cultures of Adult Rat Hepatocytes

    Mitsutoshi KIMURA*, Hajime MOTEKI, Masahiko OGIHARA
    Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Josai University
    Biological & Pharmaceutical Bulletin 34(5): 682-687, 2011.


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  • Intrathecal Disposition of ARTCEREB? Irrigation and Perfusion Solution for Cerebrospinal Surgery in Rats

    Yujiro MORIOKAa, Masuhiro NISHIMURA*a, Hiroaki TAKEHARAa, Kazuhisa DOIa, Shinsaku NAITOa, Aiko YAMAUCHIb
    aResearch and Development Center, Otsuka Pharmaceutical Factory, Inc., bDepartment of Pharmaceutical Information Science, Graduate School of Pharmaceutical Science, The University of Tokushima
    Biological & Pharmaceutical Bulletin 34(5): 688-692, 2011.


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  • Losartan and Pioglitazone Ameliorate Nephropathy in Experimental Metabolic Syndrome Rats

    Xiang KONGa, Dao-you ZHANG*b, Hai-bing WUb, Fang-xia LIb
    aDepartment of Pharmacology, Third-Grade Pharmacology Laboratory of State Administration of Traditional Chinese Medicine, Wannan Medical College, bDepartment of Nephrology, Yijishan Hospital Affiliated to Wannan Medical College
    Biological & Pharmaceutical Bulletin 34(5): 693-699, 2011.


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  • Hydrocortisone Inhibits Cellular Proliferation by Downregulating Hepatocyte Growth Factor Synthesis in Human Osteoblasts

    Yoshihiko TSUNASHIMA, Ayami KONDO†, Tomohiro MATSUDA, Akifumi TOGARI*
    Department of Pharmacology, School of Dentistry, Aichi-Gakuin University
    Biological & Pharmaceutical Bulletin 34(5): 700-703, 2011.


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  • Decreased Motility of the Lower Esophageal Sphincter in a Rat Model of Gastroesophageal Reflux Disease May Be Mediated by Reductions of Serotonin and Acetylcholine Signaling

    Yayoi SAEGUSAa,b, Hiroshi TAKEDAa,c, Shuichi MUTOc,d, Nobuhiko ORIDATEe, Koji NAKAGAWAa, Chiharu SADAKANEa,b, Miwa NAHATAb, Yumi HARADAb, Mizuki IIZUKAb, Tomohisa HATTORO*b, Masahiro ASAKAc
    aDepartment of Pathophysiology and Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, bTsumura & Co., Tsumura Research Laboratories, cGastroenterology and Hematology, Hokkaido University Graduate School of Medicine, dOtolaryngology-Head & Neck Surgery, Hokkaido University Graduate School of Medicine, eGastoenterology, Tomakomai City General Hospital
    Biological & Pharmaceutical Bulletin 34(5): 704-711, 2011.


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  • Effective Drug Delivery System for Duchenne Muscular Dystrophy Using Hybrid Liposomes Including Gentamicin along with Reduced Toxicity

    Mamiko YUKIHARAa, Kaori ITOb, Osamu TANOUEa, Koichi GOTOa, Taku MATSUSHITAa, Yoko MATSUMOTOa, Masako MASUDAc, Shigemi KIMURA*b, Ryuichi UEOKA*a
    aDivision of Applied Life Science, Graduate School of Engineering, Sojo University, bDepartment of Child Development, Kumamoto University Graduate School, cDepartment of Otolaryngology, Kumamoto University Graduate School
    Biological & Pharmaceutical Bulletin 34(5): 712-716, 2011.


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  • Genetic Diversity of Ephedra Plants in Mongolia Inferred from Internal Transcribed Spacer Sequence of Nuclear Ribosomal DNA

    Yuki KITANIa, Shu ZHIa, Javzan BATKHUUb, Chinbat SANCHIRc, Katsuko KOMATSU*a
    aDivision of Pharmacognosy, Department of Medicinal Resources, Institute of Natural Medicine, University of Toyama, bSchool of Biology and Biotechnology, National University of Mongolia, cInstitute of Biology, Mongoloian Acadeny of Science
    Biological & Pharmaceutical Bulletin 34(5): 717-726, 2011.


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  • Effects of S/B Remedy Containing Scutellaria baicalensis and Bupleurum scorzonerifolfium on Hepatic Interleukin-6 Related Signal Transducer and Activator of Transcription 3 Activation in Mice through Cell-Cell Interaction

    Chang-Yin LEEa, Jir-You WANGa,b, Tzu-Chun CHENa, Jeng-Kae JIANGc, Chi-Hao PENGa, Cheng-Deng KUOd, Wen-Chi CHANGe, Jen-Hwey CHIU*a,f,g, Chew-Wun WUf
    aInstitute of Traditional Medicine, School of Medicine, National Yang-Ming University, bDepartment of Orthopedic, Taipei Veterans General Hospital, cDivision of Colorectal Surgery, Department of Surgery, Taipei Veterans General Hospital, dDepartment of Medical Research and Education, Taipei Veterans General Hospital, eLaboratory Animal Center, National Yang-Ming University, fDivision of General Surgery, Department of Surgery, Taipei Veternas General Hospital, gDepartment of Surgery, Cheng-Hsiun Hospital
    Biological & Pharmaceutical Bulletin 34(5): 727-733, 2011.


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  • In Vitro Characterization of the Cytochrome P450 Isoforms involved in the Metabolism of 6-Methoxy-2-napthylacetic Acid, an Active Metabolite of the Prodrug Nabumetone

    Kaori MATSUMOTOa, Eiichi NEMOTOa,b, Tetsuya HASEGAWAa, Masayuki AKIMOTO*a, Kenji SUGIBAYASHIb
    aFaculty of Pharmaceutical Sciences, Josai International University, bFaculty of Pharmaceutical Sciences, Josai Univeristy
    Biological & Pharmaceutical Bulletin 34(5): 734-739, 2011.


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  • Intranasal Administration of Milnacipran in Rats:Evaluation of the Transport of Drugs to the Systemic Circulation and Central Nervous System and the Pharmacological Effect

    Masaki UCHIDAa, Takuya KATOHa, Mutsuhiro MORIb, Takuya MAENOc, Kazuo OHTAKEa, Jun KOBAYASHIa, Yasunori MORIMOTOa,d, Hideshi NATSUME*a,d
    aFaculty of Pharmaceutical Sciences, Josai University, bScientific Affairs Department, Pharmaceuticals Sales Division, Asahi Kasei Pharma Corporation, cDepartment of Pharmacy, Kosei Chuo General Hospital, dResearch Institute of TTS Technology, Josai University
    Biological & Pharmaceutical Bulletin 34(5): 740-747, 2011.


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  • Macelignan Inhibits Melanosome Transfer Mediated by Protease- Activated Receptor-2 in Keratinocytes

    Eun-Jung CHOIa, Young-Gyu KANGb, Jaekyung KIMa, Jae-Kwan HWANG*a,b
    aDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, bDepartment of Biomaterials Science and Engineering, Yonsei University
    Biological & Pharmaceutical Bulletin 34(5): 748-754, 2011.


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  • Pharmacokinetic Variability of Mycophenolic Acid and Its Glucuronide in Systemic Lupus Erythematosus Patients in Remission Maintenance Phase

    Yasuaki MINOa, Takafumi NAITOa, Kumiko SHIMOYAMAb, Noriyoshi OGAWAb, Junichi KAWAKAMI*a
    aDepratment of Hospital Pharmacy, Hamamatsu University School of Medicine, bThird Department of Internal Medicine, Hamamatsu University School of Medicine
    Biological & Pharmaceutical Bulletin 34(5): 755-759, 2011.


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  • Rab5a Regulates Surface Expression of FcεRI and Functional Activation in Mast Cells

    Natsuko KAGEYAMA-YAHARA*, Yoko SUEHIRO, Takeshi YAMAMOTO, Makoto KADOWAKI
    Division of Gastrointestinal Pathophysiology, Department of Bioscience, Institute of Natural Medicine, University of Toyama
    Biological & Pharmaceutical Bulletin 34(5): 760-763, 2011.


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  • Asynchronously Enhanced Spiking Activity of Ischemic Neuronal Networks

    Sakiko UJITAa, Mika MIZUNUMAa, Norio MATSUKIa, Yuji IKEGAYA*a,b
    aLaboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, bPrecursory Research for Embryonic Science and Technology (PRESTO)
    Biological & Pharmaceutical Bulletin 34(5): 764-767, 2011.


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  • A Glycosidic Spinasterol from Koreana stewartia Promotes Procollagen Production and Inhibits Matrix Metalloproteinase-1 Expression in UVB-Irradiated Human Dermal Fibroblasts

    Tae Hoon LEEa, Sang Min LEEa, Dae-Young LEEa, Youngsook SONa,b, Dae Kyun CHUNGa,c, Nam-In BAEKa, Jiyoung KIM*a
    aGraduate School of Biotechnology and College of Life Science, Kyung Hee University, bMusculoskeletal Bioorgan Center, Kyung Hee University, cSkin Biotechnology Center, Kyung Hee University
    Biological & Pharmaceutical Bulletin 34(5): 768-773, 2011.


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  • Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa

    Lucia Renee RUHAAK*a,b,†, Jenny FELTHa,#, Pernilla Christina KARLSSONc, Joseph James RAFTERc, Robert VERPOORTEb, Lars BoHLINa
    aDivision of Pharmacognosy, Department of Medicinal Chemistry, Biomedical Centre, Uppsala University, bDivision of Pharmacognosy, Section Metabolomics, Institute of Biology, Leiden University, cDepartment of Biosciences and Nutrition, Karolinska Institute
    Biological & Pharmaceutical Bulletin 34(5): 774-778, 2011.


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  • Identification of Dendrobium Species Used for Herbal Medicines Based on Ribosomal DNA Internal Transcribed Spacer Sequence

    Tomoko TAKAMIYA*a, Pheravut WONGSAWADb, Natsuko TAJIMAb, Nao SHIODAa, Jun Feng LUa, Chi Luan WENc, Jin Bin WUd, Takashi HANDAe, Hiroshi IIJIMAa, Susumu KITANAKAa, Tomohisa YUKAWAf
    aSchool of Pharmacy, Nihon University, bInstitute of Agriculture and Forestry, University of Tsukuba, cGradutate Institute of Chinese Pharmaceutical Sciences, China Medical University, dGraduate Institute of Pharmaceutical Chemistry, China Medical University, eSchool of Agriculture, Meiji University, fTsukuba Botanical Garden, National Museum of Nature and Science
    Biological & Pharmaceutical Bulletin 34(5): 779-782, 2011.


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book
発行元:
日本薬学会
ISSN:
0918-6158
ISSN(オンライン):
1347-5215

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Medical Online English Site