バックナンバー:Biological and Pharmaceutical Bulletin

Biological and Pharmaceutical Bulletin
41巻 4号

  • Nobiletin Reduces Intracellular and Extracellular β-Amyloid in iPS Cell-Derived Alzheimer's Disease Model Neurons

    Junko Kimura(a), Kosuke Shimizu(a), Koji Kajima(b), Akihito Yokosuka(c), Yoshihiro Mimaki(c), Naoto Oku(a), Yasushi Ohizumi(a),(d)
    (a)Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, (b)Sankyo Co.,Ltd., (c)Department of Medicinal Pharmacognosy, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, and (d)Kansei Fukushi Research Institute, Tohoku Fukushi University
    Biological and Pharmaceutical Bulletin 41(4): 451-457, 2018.


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  • A Novel Peptide from Vespa ducalis Induces Apoptosis in Osteosarcoma Cells by Activating the p38 MAPK and JNK Signaling Pathways

    Ren Wu(a), Ding Li(a), Qi Tang(a), Wanchun Wang(a), Guangrong Xie(b), Pengcheng Dou(a)
    (a)Department of Orthopedics, The Second Xiangya Hospital, Central South University, and (b)Department of Psychiatry, The Second Xiangya Hospital, Central South University
    Biological and Pharmaceutical Bulletin 41(4): 458-464, 2018.


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  • A Standard Intervention Practice to Promote Appropriate Lamotrigine Therapy by Pharmacists

    Hiroshi Shimamura(a),(b), Hiroko Yamada(a),(c), Natsumi Okada(c),(d), Takeshi Uchikura(c), Katsumi Tanaka(d), Tadanori Sasaki(c),(d), Hiroyuki Itabe(b)
    (a)Department of Pharmacy, Showa University Hospital East Branch, (b)Division of Biological Chemistry, Department of Molecular Biology, Showa University, School of Pharmacy, (c)Dpartment of Hospital Pharmaceutics, Showa University, School of Pharmacy, and (d)Department of Pharmacy, Showa University Hospital
    Biological and Pharmaceutical Bulletin 41(4): 465-469, 2018.


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  • Nardostachys jatamansi Ethanol Extract Ameliorates Aβ42 Cytotoxicity

    Quan Feng Liu(a),(b), Youngjae Jeon(c), Yung-wei Sung(a),(b), Jang Ho Lee(c), Haemin Jeong(c), Young-Mi Kim(d), Hye Sup Yun(c), Young-Won Chin(d), Songhee Jeon(e),(f), Kyoung Sang Cho(c), Byung-Soo Koo(a),(b)
    (a)Department of Oriental Medicine, Dongguk University, (b)Department of Oriental Neuropsychiatry, Graduate School of Oriental Medicine, Dongguk University, (c)Department of Biological Sciences, Konkuk University, (d)College of Pharmacy and Integrated Research Institute for Drug Development, Dongguk University-Seoul, (e)Dongguk University Research Institute of Biotechnology, Dongguk University, and (f)Department of Biomedical Sciences, BK21 PLUS Center for Creative Biomedical Scientists at Chonnam National University
    Biological and Pharmaceutical Bulletin 41(4): 470-477, 2018.


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  • Triggering of Autophagy by Baicalein in Response to Apoptosis after Spinal Cord Injury : Possible Involvement of the PI3K Activation

    Yuanlong Li, Sen Lin, Chang Xu, Peng Zhang, Xifan Mei
    Department of Orthopedics, First Affiliated Hospital of Jinzhou Medical University
    Biological and Pharmaceutical Bulletin 41(4): 478-486, 2018.


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  • Size-Based Differentiation of Cancer and Normal Cells by a Particle Size Analyzer Assisted by a Cell-Recognition PC Software

    Babita Shashni(a), Shinya Ariyasu(b), Reisa Takeda(a), Toshihiro Suzuki(c), Shota Shiina(a), Kazunori Akimoto(a),(d), Takuto Maeda(e), Naoyuki Aikawa(b),(d),(e), Ryo Abe(b),(c),(d), Tomohiro Osaki(f), Norihiko Itoh(f), Shin Aoki(a),(b),(d)
    (a)Faculty of Pharmaceutical Sciences, Tokyo University of Science, (b)Center for Technologies Against Cancer, Tokyo University of Science, (c)Research Institute for Biomedical Sciences, Tokyo University of Science, (d)Division of Medical Science-Engineering Corporation, Research Institute for Science and Technology, Tokyo University of Science, (e)Faculty of Industrial Science and Technology, Tokyo University of Science, and (f)Laboratory of Veterinary Surgery, Joint Department of Veterinary Medicine, Faculty of Agriculture, Tottori University
    Biological and Pharmaceutical Bulletin 41(4): 487-503, 2018.


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  • Effects of Products Containing Bacillus subtilis var. natto on Healthy Subjects with Neck and Shoulder Stiffness, a Double-Blind, Placebo-Controlled, Randomized Crossover Study

    Yoichi Sunagawa(a),(b),(c), Nobuko Okamura(a), Yusuke Miyazaki(a),(b),(c), Kana Shimizu(a), Mai Genpei(a), Masafumi Funamoto(a),(b), Satoshi Shimizu(a), Yasufumi Katanasaka(a),(b),(c), Eriko Morimoto(c), Hajime Yamakage(d), Maki Komiyama(b), Noriko Satoh-Asahara(d), Hiromichi Wada(b), Mika Suzuki(e), Koji Hasegawa(a),(b), Tatsuya Morimoto(a),(b),(c)
    (a)Division of Molecular Medicine, School of Pharmaceutical Sciences, University of Shizuoka, (b)Division of Translational Research, Clinical Research Institute, Kyoto Medical Center, National Hospital Organization, (c)Shizuoka General Hospital, (d)Division of Diabetic Research, Clinical Research Institute, Kyoto Medical Center, National Hospital Organization, and (e)Seirei Healthcare Support Center Shizuoka
    Biological and Pharmaceutical Bulletin 41(4): 504-509, 2018.


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  • Fluorescence Coupled with Macro and Microscopic Examinations of Morphological Phenotype Give Key Characteristics for Identification of Crude Drugs Derived from Scorpions

    Hiroko Tokumoto(a),(b), Hiroko Shimomura(a), Takashi Hakarnatsuka(a), Yoshihiro Ozeki(c), Yukihiro Goda(d)
    (a)Division of Pharmacognosy, Phytochemistry, and Narcotics, National Institute of Health Sciences, (b)Graduate School of Engineering, Tokyo University of Agriculture and Technology, (c)Department of Biotechnology and Life Science, Faculty of Engineering, Tokyo University of Agriculture and Technology, and (d)Division of Drugs, National Institute of Health Sciences
    Biological and Pharmaceutical Bulletin 41(4): 510-523, 2018.


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  • Inhibitory Effect of (-)-Epigallocatechin-3-O-gallate on Octanoylated Ghrelin Levels in Vitro and in Vivo

    Kensuke Nakajima, Shigeru Oiso, Hiroko Kariyazono
    Graduate School of Pharmaceutical Sciences, Nagasaki International University
    Biological and Pharmaceutical Bulletin 41(4): 524-529, 2018.


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  • ATRA Regulates Innate Immunity in Liver Ischemia/Reperfusion Injury via RARα/Akt/Foxo1 Signaling

    Chen Zhong(a),(b), Liyong Pu(a),(b), Mingming Fang(c), Jianhua Rao(a),(b), Xuehao Wang(a),(b)
    (a)Key Laboratory on Living Donor Liver Transplantation, National Health and Family Planning Commision, (b)Department of Liver Surgery, First Affiliated Hospital of Nanjing Medical University, and (c)Department of Neurology, Jiangsu Province Hospital on Integration of Chinese and Western Medicine, Nanjing University of Chinese Medicine
    Biological and Pharmaceutical Bulletin 41(4): 530-535, 2018.


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  • Characterization of the SN35N Strain-Specific Exopolysaccharide Encoded in the Whole Circular Genome of a Plant-Derived Lactobacillus plantarum

    Masafumi Noda(a), Masaya Shiraga(a), Takanori Kumagai(b), Narandalai Danshiitsoodol(a), Masanori Sugiyama(a)
    (a)Department of Probiotic Science for Preventive Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, and (b)Department of Microbiology, Graduate School of Biomedical and Health Sciences, Hiroshima University
    Biological and Pharmaceutical Bulletin 41(4): 536-545, 2018.


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  • Noncovalent Strategy with Cell-Penetrating Peptides to Facilitate the Brain Delivery of Insulin through the Blood-Brain Barrier

    Noriyasu Kamei, Ai Yamaoka, Yukiko Fukuyama, Rei Itokazu, Mariko Takeda-Morishita
    Laboratory of Drug Delivery Systems, Faculty of Pharmaceutical Sciences, Kobe Gakuin University
    Biological and Pharmaceutical Bulletin 41(4): 546-554, 2018.


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  • Mechanisms of the pH- and Oxygen-Dependent Oxidation Activities of Artesunate

    Katsunori Tsuda(a), Licht Miyamoto(a), Shuichi Hamano(b), Yuri Morimoto(c), Yumi Kangawa(c), Chika Fukue(c), Yoko Kagawa(c), Yuya Horinouchi(d), Wenting Xu(a), Yasumasa Ikeda(d), Toshiaki Tamaki(d), Koichiro Tsuchiya(a)
    (a)Department of Medical Pharmacology, Institute of Biomedical Sciences, University of Tokushima Graduate School, (b)Department of Cell and Immunity Analytics, Institute of Biomedical Sciences, University of Tokushima Graduate School, (c)Major in Laboratory Science, School of Health Sciences, Faculty of Medicine, Tokushima University, and (d)Department of Pharmacology, Institute of Biomedical Sciences, University of Tokushima Graduate School
    Biological and Pharmaceutical Bulletin 41(4): 555-563, 2018.


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  • Enhanced Activity of Immunosuppressive Oligodeoxynucleotides by Incorporating Them into Hexapod-Like Nanostructured DNA

    Yuki Araie(a), Yosuke Takahashi(a), Yuki Takahashi(a), Yoshinobu Takakura(a), Makiya Nishikawa(a),(b)
    (a)Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University, and (b)Laboratory of Biopharmaceutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science
    Biological and Pharmaceutical Bulletin 41(4): 564-569, 2018.


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  • The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-chronic Myelogenous Leukemia Activities

    Halil Ibrahim Ciftci(a), Safiye Emirdag Ozturk(b), Taha F.S.Ali(a),(c), Mohamed O.Radwan(a),(d), Hiroshi Tateishi(a), Ryoko Koga(a), Zeynep Ocak(e), Mustafa Can(f), Masami Otsuka(a), Mikako Fujita(g)
    (a)Department of Bioorganic Medicinal Chemistry, Faculty of Life Sciences, Kumamoto University, (b)Chemistry Department, Faculty of Science, Ege University, (c)Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, (d)Department of Chemistry of Natural Compounds, National Research Center, (e)Microbiology Laboratory, Izmit Seka State Hospital, (f)Department of Engineering Sciences, Faculty of Engineering and Architecture, Izmir Katip Celebi University, and (g)Research Institute for Drug Discovery, School of Pharmacy, Kumamoto University
    Biological and Pharmaceutical Bulletin 41(4): 570-574, 2018.


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  • Isosteviol Sodium Inhibits Astrogliosis after Cerebral Ischemia / Reperfusion Injury in Rats

    Hao Zhang(a), Xiaoou Sun(b), Yanxiang Xie(a), Fang Tian(a), Hui Hu(b), Wen Tan(b)
    (a)School of Bioscience & Bioengineering, South China University of Technology, and (b)Institute of Biomedical & Pharmaceutical Sciences, Guangdong University of Technology
    Biological and Pharmaceutical Bulletin 41(4): 575-584, 2018.


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  • Ginsenoside-Rg1 Protects against Renal Fibrosis by Regulating the Klotho/TGF-β1/Smad Signaling Pathway in Rats with Obstructive Nephropathy

    Sha-sha Li(a), Ao-lin He(a), Zhi-yong Deng(b), Qi-feng Liu(c)
    (a)Clinical Research & Lab Centre, Kunshan First People's Hospital Affiliated to Jiangsu University, (b)Department of Pathology, Kunshan First People's Hospital Affiliated to Jiangsu University, and (c)Department of Nephrology, Kunshan First People's Hospital Affiliated to Jiangsu University
    Biological and Pharmaceutical Bulletin 41(4): 585-591, 2018.


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  • Validating a Selective S1P1 Receptor Modulator Syl930 for Psoriasis Treatment

    Ming Ji(a),(b), Nina Xue(a), Fangfang Lai(a), Xiaoying Zhang(a), Sen Zhang(b), Yuchen Wang(b), Jing Jin(a),(b), Xiaoguang Chen(a),(b)
    (a)State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, and (b)Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College
    Biological and Pharmaceutical Bulletin 41(4): 592-596, 2018.


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  • Studies on the Unusual 1β-Hydroxylated Bile Acid Biosynthesis in Infants

    Yukihiro Nomura(a), Hiroyuki Murata(a), Hiroaki Sasai(a), Akihiko Kimura(b), Takao Kurosawa(c), Takahiro Sasaki(c), Tsuyoshi Murai(c)
    (a)Drug Metabolism and Pharmacokinetics Research Laboratories, Central Pharmaceutical Research Institute, Japan Tobacco Inc., (b)Department of Pediatrics and Child Health, Kurume University School of Medicine, and (c)School of Pharmaceutical Sciences, Health Sciences University of Hokkaido
    Biological and Pharmaceutical Bulletin 41(4): 597-603, 2018.


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  • Reduction of Membrane Protein CRIM1 Decreases E-Cadherin and Increases Claudin-1 and MMPs, Enhancing the Migration and Invasion of Renal Carcinoma Cells

    Nobutaka Ogasawara(a), Tamami Kudo(a), Masaki Sato(a), Yasushi Kawasaki(a), Sei Yonezawa(a), Satoru Takahashi(b), Yohei Miyagi(c), Yasuhiro Natori(a), Akinori Sugiyama(a)
    (a)Department of Health Chemistry, School of Pharmacy, Iwate Medical University, (b)Department of Immunobiology, School of Pharmacy and Pharmaceutical Science, Mukogawa Women's University, and (c)Division of Molecular Pathology and Genetics, Kanagawa Cancer Center Research Institute
    Biological and Pharmaceutical Bulletin 41(4): 604-611, 2018.


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  • Virion-Packaged Pyruvate Kinase Muscle Type 2 Affects Reverse Transcription Efficiency of Human Immunodeficiency Virus Type 1 by Blocking Virion Recruitment of tRNA Lys3

    Kumkum Rahman Mouree(a), Naoki Kishimoto(a), Nozomi Iga(a), Chie Kirihara(a), Kengo Yamamoto(a), Nobutoki Takamune(b), Shogo Misumi(a)
    (a)Department of Environmental and Molecular Health Sciences, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, and (b)Innovative Collaboration Organization, Kumamoto University
    Biological and Pharmaceutical Bulletin 41(4): 612-618, 2018.


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  • Investigation of Metabolomic Changes in Sunitinib-Resistant Human Renal Carcinoma 786-O Cells by Capillary Electrophoresis-Time of Flight Mass Spectrometry

    Hiroto Hatakeyama, Takuya Fujiwara, Hiromi Sato, Ayu Terui, Akihiro Hisaka
    Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University
    Biological and Pharmaceutical Bulletin 41(4): 619-627, 2018.


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  • Characterization of Non-amyloidogenic G101S Transthyretin

    Yuriko Wakita(a),(b), Takashi Sato(c), Keisuke Chosa(a), Mary Ann Suico(a), Ryoko Sasaki(a), Shingo Kawano(c), Nami Hashimoto(a), Yuriko Teranishi(a), Yoshiki Imai(a),(b), Hiroshi Morioka(c), Tsuyoshi Shuto(a), Hirofumi Kai(a)
    (a)Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, (b)Program for Leading Graduate Schools "HIGO (Health life science: Interdisciplinary and Glocal Oriented) Program", and (c)Department of Analytical and Biophysical Chemistry, Kumamoto University
    Biological and Pharmaceutical Bulletin 41(4): 628-636, 2018.


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  • Anti-mouse RANKL Antibodies Inhibit Alveolar Bone Destruction in Periodontitis Model Mice

    Miku Kuritani(a),(b), Nobuhiro Sakai(a), Akiko Karakawa(a), Motoki Isawa(a),(c), Masahiro Chatani(a), Takako Negishi-Koga(a), Takahiro Funatsu(b), Masamichi Takami(a)
    (a)Department of Pharmacology, School of Dentistry, Showa University, (b)Department of Special Needs Dentistry, Division of Dentistry for Persons with Disabilities, School of Dentistry, Showa University, and (c)Department of Pediatric Dentistry, School of Dentistry, Showa University
    Biological and Pharmaceutical Bulletin 41(4): 637-643, 2018.


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  • Hypertension and Proteinuria as Predictive Factors of Effects of Bevacizumab on Advanced Breast Cancer in Japan

    Hiroaki Tanaka(a), Koichi Takahashi(a), Kazunori Yamaguchi(a), Keiichi Kontani(b), Takahiro Motoki(a), Masato Asakura(a), Shinji Kosaka(a), Hiroyasu Yokomise(b), Hitoshi Houchi(a)
    (a)Department of Pharmacy, Kagawa University Hospital, and (b)Department of Respiratory, Breast and Endocrine Surgery, Kagawa University Hospital
    Biological and Pharmaceutical Bulletin 41(4): 644-648, 2018.


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  • A Novel Method for Determination of Methadone in the Serum by High-Performance Liquid Chromatography with Electrochemical Detection

    Hideya Kokubun(a), Chizuko Takigawa(b), Kanako Miyano(c), Yasuhito Uezono(c),(d)
    (a)Tokyo University of Pharmacy and Life Sciences, (b)Department of Palliative Medicine, KKR Sapporo Medical Center, (c)Division of Cancer Pathophysiology, National Cancer Center Research Institute, and (d)Innovation Center for Supportive, Palliative and Psychosocial Care, National Cancer Center Hospital
    Biological and Pharmaceutical Bulletin 41(4): 649-651, 2018.


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  • Involvement of Tumor Lymphatic System in Translocation of Intratumorally Injected Liposomes

    Kosuke Shimizu, Satomi Yamaguchi Ikeuchi, Ai Okajima, Genki Nakamura, Eiichi Muraoka, Naoto Oku
    Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka
    Biological and Pharmaceutical Bulletin 41(4): 652-656, 2018.


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  • GYY4137, an Extended-Release Hydrogen Sulfide Donor, Reduces NMDA-Induced Neuronal Injury in the Murine Retina

    Kohei Sone, Asami Mori, Kenji Sakamoto, Tsutomu Nakahara
    Department of Molecular Pharmacology, Kitasato University School of Pharmaceutical Sciences
    Biological and Pharmaceutical Bulletin 41(4): 657-660, 2018.


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book
発行元:
日本薬学会
ISSN:
0918-6158
ISSN(オンライン):
1347-5215

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Medical Online English Site