バックナンバー:Biological and Pharmaceutical Bulletin

Biological and Pharmaceutical Bulletin
41巻 5号

  • Development and Evaluation of Antibody Proteomics Technology for Rapid and Comprehensive Identification of Potential Biomarkers and Therapeutic Targets

    Kazuya Nagano
    Laboratory of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University
    Biological and Pharmaceutical Bulletin 41(5): 663-669, 2018.


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  • Gastrodin Protects against Ethanol-Induced Liver Injury and Apoptosis in HepG2 Cells and Animal Models of Alcoholic Liver Disease

    Yong Zhang(a), Can Wang(b), Bin Yu(a), Jian-Dong Jiang(b), Wei-Jia Kong(a)
    (a)Department of Virology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, and (b)State Key Laboratory of Bioactive Natural Products and Function, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College
    Biological and Pharmaceutical Bulletin 41(5): 670-679, 2018.


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  • Dibenzoylmethane Suppresses Lipid Accumulation and Reactive Oxygen Species Production through Regulation of Nuclear Factor (Erythroid-Derived 2)-Like 2 and Insulin Signaling in Adipocytes

    Joo Hyoun Kim(a), Chae Young Kim(b), Bobin Kang(b), Jungil Hong(a), Hyeon-Son Choi(a)
    (a)Department of Food Sciencfe and Technology, College of Natural Science, Seoul Women's University, and (b)Department of Public Health Sciences, Korea University
    Biological and Pharmaceutical Bulletin 41(5): 680-689, 2018.


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  • Ligustrazine Enhances the Hypnotic and Analgesic Effect of Ketamine in Mice

    Chuiliang Liu(a), Zhipeng Li(a), Zeqi Huang(b),(c), Kun Zhang(b),(c), Chuwen Hu(b),(c), Zhiyi Zuo(b),(c),(d), Yujuan Li(b),(c)
    (a)Department of Anesthesiology, ChanCheng Center Hospital, (b)Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, (c)Laboratory of RNA and Major Diseases of Brain and Hearts, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, and (d)Department of Anesthesiology, University of Virginia Health System
    Biological and Pharmaceutical Bulletin 41(5): 690-696, 2018.


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  • Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies

    Yuma Ishizaki(a), Tomomi Furihata(a),(b), Yusuke Oyama(c), Kayoko Ohura(c), Teruko Imai(c), Masakiyo Hosokawa(d), Hidetaka Akita(a), Kan Chiba(a)
    (a)Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, (b)Department of Pharmacology, Graduate School of Medicine, Chiba University, (c)Department of Metabolism-Based Drug Design and Delivery, Graduate School of Pharmaceutical Science, Kumamoto University, and (d)Laboratory of Drug Metabolism and Biopharmaceutics, Faculty of Pharmaceutical Sciences, Chiba Institute of Science
    Biological and Pharmaceutical Bulletin 41(5): 697-706, 2018.


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  • Effects of Oridonin on Hepatic Cytochrome P450 Expression and Activities in PXR-Humanized Mice

    Zhang Yi-wen(a),(b),(c), Bao Mei-hua(a),(b),(d), Lou Xiao-ya(a),(b), Cheng Yu(a),(b), Yu Jing(a),(b), Zhou Hong-hao(a),(b)
    (a)Department of Clinical Pharmacology, Xiangya Hospital, Central South University, (b)Institute of Clinical Pharmacology, Central South University, Hunan Key Laboratory of Pharmacogenetics, (c)Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province, Zhejiang Cancer Hospital, and (d)Department of Anatomy, Histology and Embryology, Changsha Medical University
    Biological and Pharmaceutical Bulletin 41(5): 707-712, 2018.


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  • Induction of Apoptosis by Citrus unshiu Peel in Human Breast Cancer MCF-7 Cells : Involvement of ROS-Dependent Activation of AMPK

    Min Yeong Kim(a),(b), Hyun Hwang Bo(a),(b), Eun Ok Choi(a),(b), Da He Kwon(a),(b), Hong Jae Kim(a),(b), Kyu Im Ahn(a),(b), Seon Yeong Ji(a),(b), Jin-Woo Jeong(a),(b), Shin-Hyung Park(c), Su-Hyun Hong(a),(b), Gi-Young Kim(d), Cheol Park(e), Heui-Soo Kim(f), Sung-Kwon Moon(g), Seok-Joong Yun(h), Wun Jae Kim(h), Yung Hyun Choi(a),(b)
    (a)Department of Biochemistry, Dongeui University College of Korean Medicine, (b)Anti-Aging Research Center, Dongeui University, (c)Department of Pathology, Dongeui University College of Korean Medicine, (d)Laboratory of Immunobiology, Department of Marine Life Sciences, Jeju National University, (e)Department of Molecular Biology, College of Natural Sciences, Dongeui University, (f)Department of Biological Sciences, College of Natural Sciences, Pusan National University, (g)Department of Food and Nutrition, College of Biotechnology & Natural Resource, Chung-Ang University, and (h)Personalized Tumor Engineering Research Center, Department of Urology, Chungbuk National University College of Medicine
    Biological and Pharmaceutical Bulletin 41(5): 713-721, 2018.


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  • Comparison of Drug Metabolism and Its Related Hepatotoxic Effects in HepaRG, Cryopreserved Human Hepatocytes, and HepG2 Cell Cultures

    Yuichi Yokoyama(a),(b), Yoshifumi Sasaki(a), Natsuko Terasaki(a), Taku Kawataki(a), Koji Takekawa(a), Yumiko Iwase(a), Toshinobu Shimizu(b), Seigo Sanoh(b), Shigeru Ohta(b)
    (a)Safety Research Laboratories, Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, and (b)Graduate School of Biomedical and Health Sciences, Hiroshima University
    Biological and Pharmaceutical Bulletin 41(5): 722-732, 2018.


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  • A Novel Strategy to Increase the Yield of Exosomes (Extracellular Vesicles) for an Expansion of Basic Research

    Sherif E.Emam(a),(b), Hidenori Ando(a), Amr Selim Abu Lila(a),(b),(c), Taro Shimizu(a), Masami Ukawa(a), Keiichiro Okuhira(d), Yu Ishima(a), Mahmoud A.Mahdy(b), Fakhr-eldin S.Ghazy(b), Tatsuhiro Ishida(a)
    (a)Department of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical Sciences, Tokushima University, (b)Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Zagazig University, (c)Department of Pharmaceutics, College of Pharmacy, Hail University, and (d)Department of Molecular Physical Pharmaceutics, Institute of Biomedical Sciences, Tokushima University
    Biological and Pharmaceutical Bulletin 41(5): 733-742, 2018.


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  • Sphingoid Base-Upregulated Caspase-14 Expression Involves MAPK

    Yukitoshi Nagahara, Kei Kawakami, Abudubari Sikandan, Daiki Yagi, Ryo Nishikawa, Takahisa Shinomiya
    Division of Life Science and Engineering, School of Science and Engineering, Tokyo Denki University
    Biological and Pharmaceutical Bulletin 41(5): 743-748, 2018.


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  • Antioxidant Activity of Ge-132, a Synthetic Organic Germanium, on Cultured Mammalian Cells

    Takeyoshi Wada(a), Takashi Hanyu(a), Kota Nozaki(a), Kosuke Kataoka(a), Tomoro Kawatani(a), Toru Asahi(a),(b), Naoya Sawamura(a),(b)
    (a)Faculty of Science and Engineering, Waseda University, and (b)Research Organization for Nano & Life Innovation, Waseda University
    Biological and Pharmaceutical Bulletin 41(5): 749-753, 2018.


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  • Influence of Polysorbate 60 on Formulation Properties and Bioavailability of Morin-Loaded Nanoemulsions with and without Low-Saponification-Degree Polyvinyl Alcohol

    Yuri Ikeuchi-Takahashi(a), Ayaka Kobayashi(b), Chizuko Ishihara(b), Takumi Matsubara(a), Hiroaki Matsubara(a), Hiraku Onishi(a)
    (a)Department of Drug Delivery Research, Hoshi University, and (b)The Nippon Synthetic Chemical Industry Co., Ltd.
    Biological and Pharmaceutical Bulletin 41(5): 754-760, 2018.


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  • Protective Effect of Ipragliflozin on Pancreatic Islet Cells in Obese Type 2 Diabetic db/db Mice

    Toshiyuki Takasu, Shoji Takakura
    Tsukuba Research Center, Drug Discovery Research, Astellas Pharma Inc.
    Biological and Pharmaceutical Bulletin 41(5): 761-769, 2018.


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  • Mansonone E from Mansonia gagei Inhibited α-MSH-Induced Melanogenesis in B16 Cells by Inhibiting CREB Expression and Phosphorylation in the PI3K/Akt Pathway

    Atsuyoshi Nishina(a), Airi Miura(a), Masaharu Goto(a), Kahori Terakado(a), Daisuke Sato(b), Hirokazu Kimura(c), Yasuaki Hirai(d), Hiroyasu Sato(e), Nyunt Phay(f)
    (a)College of Science and Technology, Nihon University, (b)Department of Biomedical Information Engineering, Graduate School of Medical Science, Yamagata University, (c)School of Medical Technology, Faculty of Health Science, Gunma Paz University, (d)Faculty of Arts and Sciences, Showa University, (e)Rigaku Corporation, and (f)Botany Department, Pathein University
    Biological and Pharmaceutical Bulletin 41(5): 770-776, 2018.


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  • Hydrogen Peroxide-Reducing Factor Released by PC12D Cells Increases Cell Tolerance against Oxidative Stress

    Asami Muraishi(a), Emi Haneta(a), Yoshiro Saito(a), Yutaka Hitomi(b), Mamoru Sano(c), Noriko Noguchi(a)
    (a)Systems Life Sciences Laboratory, Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, (b)Department of Molecular Chemistry and Biochemistry, Faculty of Science and Engineering, Doshisha University, and (c)Department of Biology, Kyoto Prefectural University of Medicine
    Biological and Pharmaceutical Bulletin 41(5): 777-785, 2018.


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  • Calcineurin B1 Deficiency in Glial Cells Induces Mucosal Degeneration and Inflammation in Mouse Small Intestine

    Maya Fujita, Takaki Yagi, Umi Okura, Jun'ichi Tanaka, Naohide Hirashima, Masahiko Tanaka
    Department of Cellular Biophysics, Graduate School of Pharmaceutical Sciences, Nagoya City University
    Biological and Pharmaceutical Bulletin 41(5): 786-796, 2018.


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  • Knockout of Ceramide Kinase Aggravates Pathological and Lethal Responses in Mice with Experimental Colitis

    Satomi Suzuki, Ai Tanaka, Hiroyuki Nakamura, Toshihiko Murayama
    Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University
    Biological and Pharmaceutical Bulletin 41(5): 797-805, 2018.


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  • Biochemical Characterization of Ferulic Acid and Caffeic Acid Which Effectively Inhibit Melanin Synthesis via Different Mechanisms in B16 Melanoma Cells

    Hiroko Maruyama(a), Fumitaka Kawakami(b), Thet-Thet Lwin(c), Motoki Imai(a), Fazel Shamsa(d)
    (a)Cytopathology, Graduate School of Medical Sciences, Kitasato University, (b)Molecular Signal Biology, Graduate School of Medical Sciences, Kitasato University, (c)Molecular Imaging, Graduate School of Medical Sciences, Kitasato University, and (d)Department of Medicinal Chemistry, Faculty of Pharmacy, Teheran University of Medical Sciences
    Biological and Pharmaceutical Bulletin 41(5): 806-810, 2018.


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  • Combination Strategy with Complexation Hydrogels and Cell-Penetrating Peptides for Oral Delivery of Insulin

    Yu Fukuoka(a), El-Sayed Khafagy(b),(c), Takahiro Goto(a), Noriyasu Kamei(b), Kozo Takayama(a), Nicholas A.Peppas(d), Mariko Takeda-Morishita(b)
    (a)Department of Pharmaceutics, Hoshi University, (b)Laboratory of Drug Delivery Systems, Faculty of Pharmaceutical Sciences, Kobe Gakuin University, (c)Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Suez Canal University, and (d)Departments of Chemical and Biomedical Engineering, Department of Surgery, Dell Medical School and Division of Pharmaceutics, The University of Texas at Austin
    Biological and Pharmaceutical Bulletin 41(5): 811-814, 2018.


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  • Impairment of Protease-Activated Receptor 2-Induced Relaxation of Aortas of Aged Spontaneously Hypertensive Rat

    Makoto Ando, Takayuki Matsumoto, Shota Kobayashi, Maika Iguchi, Kumiko Taguchi, Tsuneo Kobayashi
    Department of Physiology and Morphology, Institute of Medicinal Chemistry, Hoshi University
    Biological and Pharmaceutical Bulletin 41(5): 815-819, 2018.


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  • Diabetes Mellitus Induces Hyperreactivity of 5-Hydroxytryptamine (5-HT)-Induced Constriction in Human Internal Thoracic Artery and Is Associated with Increase in the Membrane Protein Level of 5-HT 2A Receptor

    Tatsuo Shiba(a), Atsuko Yokota(b),(c), Shuji Gamoh(a), Naoko Tanaka-Totoribe(a), Masachika Kuwabara(d), Eisaku Nakamura(c), Takahiro Hayase(b), Kunihide Nakamura(c), Ryuichi Yamamoto(a)
    (a)First Department of Pharmacology, Graduate School of Clinical Pharmacy, Kyushu University of Health and Welfare, (b)Department of Cardiovascular Surgery, Miyazaki Prefectural Nobeoka Hospital, (c)Department of Surgery, Faculty of Medicine, Miyazaki University, and (d)Kuwabara Clinic
    Biological and Pharmaceutical Bulletin 41(5): 820-823, 2018.


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  • 3-O-Glyceryl-2-O-hexyl Ascorbate Suppresses Melanogenesis through Activation of the Autophagy System

    Yushi Katsuyama(a), Norihisa Taira(a), Masato Yoshioka(a), Yuri Okano(b), Hitoshi Masaki(b)
    (a)SEIWA KASEI Co.,Ltd., and (b)School of Bioscience and Biotechnology, Tokyo University of Technology
    Biological and Pharmaceutical Bulletin 41(5): 824-827, 2018.


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  • Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits

    Yoshiro Saito(a), Hirofumi Misu(b),(c), Hiroaki Takayama(b),(d), Shin-ichiro Takashima(d), Soichiro Usui(d), Masayuki Takamura(d), Shuichi Kaneko(d), Toshinari Takamura(b), Noriko Noguchi(a)
    (a)Systems Life Sciences Laboratory, Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, (b)Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medical Sciences, (c)PRESTO, Japan Science and Technology Agency, and (d)Department of Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Sciences
    Biological and Pharmaceutical Bulletin 41(5): 828-832, 2018.


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book
発行元:
日本薬学会
ISSN:
0918-6158
ISSN(オンライン):
1347-5215

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