バックナンバー:Chemical and Pharmaceutical Bulletin

Chemical and Pharmaceutical Bulletin
64巻 8号

  • Search for New Bioactive Marine Natural Products and Application to Drug Development

    Jun'ichi Kobayashi
    Graduate School of Pharmaceutical Sciences, Hokkaido University
    Chemical and Pharmaceutical Bulletin 64(8): 1079-1083, 2016.


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  • Deposits from Creams Containing 20% (w/w) Urea and Suppression of Crystallization (Part 1) : Rate of Crystallization from Cream Containing 20% (w/w) Urea and Evaluation of the Properties of the Deposit

    Norio Goto(a),†, Yutaka Morita(b), Katsuhide Terada(c),‡
    (a)Eisai Co.,Ltd., Honjo Research Section Drug Development Technology Center, Customer Joy Department Eisai Japan, (b)Research & Development Div., Elmed Eisai Co.,Ltd., (c)Faculty of Pharmaceutical Sciences, Toho University, †Present address:Eisai Co.,Ltd., Customer Joy Department Eisai Japan, ‡Present address:Faculty of Pharmaceutical Sciences, Takasaki University of Health and Welfare
    Chemical and Pharmaceutical Bulletin 64(8): 1084-1091, 2016.


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  • Deposits from Creams Containing 20% (w/w) Urea and Suppression of Crystallization (Part 2) : Novel Analytical Methods of Urea Accumulated in the Stratum Corneum by Tape stripping and Colorimetry

    Norio Goto(a),†, Yutaka Morita(b), Katsuhide Terada(c),‡
    (a)Honjo Reserch Section Drug Development Technology Center, Customer Joy Department Eisai Japan, Eisai Co.,Ltd., (b)Reserch & Development Div., Elmed Eisai Co.,Ltd., (c)Faculty of Pharmaceutical Sciences, Toho University, †Present address:Customer Joy Department Eisai Japan, Eisai Co.,Ltd., ‡Present address:Faculty of Pharmaceutical Sciences, Takasaki University of Health and Welfare
    Chemical and Pharmaceutical Bulletin 64(8): 1092-1098, 2016.


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  • Deposits from Creams Containing 20% (w/w) Urea and Suppression of Crystallization (Part 3) : Novel Analytical Methods Based on Raman Spectroscopy for the Characterization of Deposits and Deposition Phenomena of Creams Containing 20% (w/w) Urea

    Norio Goto(a),†, Yutaka Morita(b), Katsuhide Terada(c),‡
    (a)Eisai Co.,Ltd., Honjo Research Section Drug Development Technology Center, Customer Joy Department Eisai Japan, (b)Research & Development Div., Elmed Eisai Co.,Ltd., (c)Faculty of Pharmaceutical Sciences, Toho University, †Present address:Eisai Co.,Ltd., Customer Joy Department Eisai Japan, ‡Present address:Faculty of Pharmaceutical Sciences, Takasaki University of Health and Welfare
    Chemical and Pharmaceutical Bulletin 64(8): 1099-1107, 2016.


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  • Formulation and Evaluation of a Self-microemulsifying Drug Delivery System Containing Bortezomib

    Eon-Pyo Hong(a),(b), Ju-Young Kim(c), Su-Hyeon Kim(d), Kyu-Mok Hwang(d), Chun-Woong Park(e), Hyo-Jung Lee(e), Dong-Wook Kim(f), Kwon-Yeon Weon(g), Seo Young Jeong(a), Eun-Seok Park(d)
    (a)College of Pharmacy, Kyung Hee University, (b)R&D Center, Handok Inc., (c)College of Pharmacy, Woosuk University, (d)School of Pharmacy, Sungkyunkwan University, (e)College of Pharmacy, Chungbuk National University, (f)Department of Pharmaceutical Engineering, Cheongju University, (g)College of Pharmacy, Catholic University of Daegu
    Chemical and Pharmaceutical Bulletin 64(8): 1108-1117, 2016.


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  • The Safety and Immunological Effects of rAd5-EBV-LMP2 Vaccine in Nasopharyngeal Carcinoma Patients : A Phase I Clinical Trial and Two-Year Follow-Up

    Yongfeng Si(a), Zhuoxia Deng(a), Guiping Lan(a), Haijun Du(b), Yongli Wang(a), Jinyuan Si(c), Jiazhang Wei(a), Jingjin Weng(a), Yangda Qin(a), Bo Huang(a), Yong Yang(a), Ying Qin(a)
    (a)Department of Otolaryngology-Head and Neck Oncology, The People's Hospital of Guangxi Zhuang Autonomous Region, (b)State Key Laboratory for Infections Disease Prevention and Control, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, (c)Department of Otolaryngology-Head & Neck Surgery, Xuanwu Hospital, Capital Medical University
    Chemical and Pharmaceutical Bulletin 64(8): 1118-1123, 2016.


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  • False HDAC Inhibition by Aurone Compound

    Yukihiro Itoh(a), Miki Suzuki(a), Taiji Matsui(b), Yosuke Ota(a), Zi Hui(a), Kazunori Tsubaki(b), Takayoshi Suzuki(a)
    (a)Graduate School of Medical Science, Kyoto Prefectural University of Medicine, (b)Graduate School for Life and Environmental Sciences, Kyoto Prefectural University
    Chemical and Pharmaceutical Bulletin 64(8): 1124-1128, 2016.


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  • Quantification of Pharmaceutical Compounds Based on Powder X-Ray Diffraction with Chemometrics

    Yuta Otsuka(a), Akira Ito(a), Saki Matsumura(b), Masaki Takeuchi(b),(c), Suvra Pal(d), Hideji Tanaka(b),(c)
    (a)Graduate School of Pharmaceutical Sciences, Tokushima University, (b)Faculty of Pharmaceutical Sciences, Tokushima University, (c)Institute of Biomedical Sciences, Tokushima University, (d)Department of Mathematics, University of Texas at Arlington
    Chemical and Pharmaceutical Bulletin 64(8): 1129-1135, 2016.


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  • Synthesis and Biological Evaluation of 1-(2-Aminophenyl)-3-arylurea Derivatives as Potential EphA2 and HDAC Dual Inhibitors

    Yong Zhu(a), Ting Ran(b), Xin Chen(a), Jiaqi Niu(a), Shuang Zhao(a), Tao Lu(a),(c), Weifang Tang(a)
    (a)Department of Organic Chemistry, China Pharmaceutical University, (b)Laboratory of Molecular Design and Drug Discovery, School of Sciences, China Pharmaceutical University, (c)State Key Laboratory of Natural Medicines, China Pharmaceutical University
    Chemical and Pharmaceutical Bulletin 64(8): 1136-1141, 2016.


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  • Mechanical Stress Simulation of Scored Tablets Based on the Finite Element Method and Experimental Verification

    Nobuto Okada(a), Yoshihiro Hayashi(b), Yoshinori Onuki(b), Takahiro Miura(c), Yasuko Obata(a), Kozo Takayama(a)
    (a)Department of Pharmaceutics, Hoshi University, (b)Department of Pharmaceutical Technology, Graduate School of Medical and Pharmaceutical Science, University of Toyama, (c)Mechanical CAE Division, Cybernet Systems Company, Ltd.
    Chemical and Pharmaceutical Bulletin 64(8): 1142-1148, 2016.


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  • Convergent Synthesis of Dronedarone, an Antiarrhythmic Agent

    Takashi Okitsu, Mizuki Ogasahara, Akimori Wada
    Department of Organic Chemistry for Life Science, Kobe Pharmaceutical University
    Chemical and Pharmaceutical Bulletin 64(8): 1149-1153, 2016.


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  • Development of a Sulfur-Modified Glass-Supported Pd Nanoparticle Catalyst for Suzuki-Miyaura Coupling

    Mincen Xiao(a), Naoyuki Hoshiya(b),(c), Katsumasa Fujiki(a), Tetsuo Honma(d), Yusuke Tamenori(d), Satoshi Shuto(b), Hiromichi Fujioka(a), Mitsuhiro Arisawa(a),(b)
    (a)Graduate School of Pharmaceutical Sciences, Osaka University, (b)Faculty of Pharmaceutical Sciences, Hokkaido University, (c)Department of Pharmaceutical Chemistry, Kyoto Pharmaceutical University, (d)Japan Synchrotron Radiation Research Institute
    Chemical and Pharmaceutical Bulletin 64(8): 1154-1160, 2016.


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  • Preparation and Characterization of Four Stereoisomers of Monatin

    Yusuke Amino(a), Shigeru Kawahara(b), Kenichi Mori(c), Kazuko Hirasawa(a), Hiroyuki Sakata(d), Tatsuki Kashiwagi(a)
    (a)Institute for Innovation, Ajinomoto Co.,Inc., (b)Tokai Plant, Ajinomoto Co.,Inc., (c)Research Institute for Bioscience Products & Fine Chemicals, Ajinomoto Co.,Inc., (d)Institute of Food Research and Technologies, Ajinomoto Co.,Inc.
    Chemical and Pharmaceutical Bulletin 64(8): 1161-1171, 2016.


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  • Design, Synthesis and Biological Evaluation of Some 5-Arylthieno[2,3-d]-pyrimidines as Potential Anti-cancer Agents

    Afaf Kamal El-Ansary, Aliaa Mohammed Kamal, Mokhtar Abd-Hafiz Al-Ghorafi
    Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University
    Chemical and Pharmaceutical Bulletin 64(8): 1172-1180, 2016.


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  • Structure-CaSR-Activity Relation of Kokumi γ-Glutamyl Peptides

    Yusuke Amino(a), Masakazu Nakazawa(b), Megumi Kaneko(a), Takashi Miyaki(c), Naohiro Miyamura(c), Yutaka Maruyama(a), Yuzuru Eto(a)
    (a)Institute for Innovation, Ajinomoto Co.,Inc., (b)Research Institute for Bioscience Products & Fine Chemicals, Ajinomoto Co.,Inc., (c)Institute of Food Research and Technologies, Ajinomoto Co.,Inc.
    Chemical and Pharmaceutical Bulletin 64(8): 1181-1189, 2016.


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  • Synthesis of Diastereomers of 1,3-cis-25-Dihydroxy-19-norvitamin D3

    Kosuke Usuda(a), Tanima Biswas(b), Takuya Yamaguchi(a), Yusuke Akagi(a), Koji Yasui(a), Motonari Uesugi(c),(d), Isao Shimizu(b), Seijiro Hosokawa(b), Kazuo Nagasawa(a)
    (a)Graduate School of Technology, Tokyo University of Agriculture and Technology, (b)Faculty of Science and Technology, Waseda University, (c)Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, (d)Institute for Chemical Research, Kyoto University
    Chemical and Pharmaceutical Bulletin 64(8): 1190-1195, 2016.


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  • Statistical Analysis of the Impact of Molecular Descriptors on Cytotoxicity of Thiourea Derivatives Incorporating 2-Aminothiazole Scaffold

    Anna Filipowska(a), Wojciech Filipowski(a), Ewaryst Tkacz(b), Grazyna Nowicka(c), Marta Struga(c)
    (a)Faculty of Automatic Control, Electronics and Computer Science, Silesian University of Technology, (b)Department of Biosensors and Processing of Biomedical Signals, Silesian University of Technology, (c)Department of Pharmacogenomics, Faculty of Pharmacy, Medical University of Warsaw
    Chemical and Pharmaceutical Bulletin 64(8): 1196-1202, 2016.


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  • Synthesis and Biological Evaluation of 3-Benzylidene-4-chromanone Derivatives as Free Radical Scavengers and α-Glucosidase Inhibitors

    Koichi Takao, Marimo Yamashita, Aruki Yashiro, Yoshiaki Sugita
    Laboratory of Bioorganic Chemistry, Department of Pharmaceutical and Health Sciences, Faculty of Pharmaceutical Sciences, Josai University
    Chemical and Pharmaceutical Bulletin 64(8): 1203-1207, 2016.


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  • Synthesis, Structure Characterization and Antitumor Activity Study of a New Iron(III) Complex of 5-Nitro-8-hydroxylquinoline (HNOQ)

    Hai-Rong Zhang(a),(b),(c), Ting Meng(b), Yan-Cheng Liu(b), Qi-Pin Qin(b), Zhen-Feng Chen(b), You-Nian Liu(a), Hong Liang(a),(b)
    (a)College of Chemistry and Chemical Engineering, Central South University, (b)State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry & Pharmaceutical Sciences, Guangxi Normal University, (c)College of Materials and Environmental Engineering, Hunan University of Humanities, Science and Technology
    Chemical and Pharmaceutical Bulletin 64(8): 1208-1217, 2016.


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  • Photostable Solid Dispersion of Nifedipine by Porous Calcium Silicate

    Yumi Fujimoto, Nobuaki Hirai, Tomoka Takatani-Nakase, Koichi Takahashi
    Department of Pharmaceutics, School of Pharmaceutical Sciences, Mukogawa Women's University
    Chemical and Pharmaceutical Bulletin 64(8): 1218-1221, 2016.


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  • New 3,4-seco-Grayanane Diterpenoids from the Flowers of Pieris japonica

    Lang Cao, Yanping Li, Hongmei Li, Dan Liu, Rongtao Li
    Faculty of Life Science and Technology, Kunming University of Science and Technology
    Chemical and Pharmaceutical Bulletin 64(8): 1222-1225, 2016.


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  • Quantitative Appearance Inspection for Film Coated Tablets

    Hiroyuki Yoshino(a),(b), Kazunari Yamashita(a), Yasunori Iwao(b), Shuji Noguchi(b), Shigeru Itai(b)
    (a)Pharmaceutical Research & Technology Laboratories, Astellas Pharma Inc., (b)Department of Pharmaceutical Engineering, Graduate School of Pharmaceutical Sciences, University of Shizuoka
    Chemical and Pharmaceutical Bulletin 64(8): 1226-1229, 2016.


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  • Morinlongosides A-C, Two New Naphthalene Glycoside and a New Iridoid Glycoside from the Roots of Morinda longissima

    Nguyen Manh Cuong(a), Tran Thu Huong(a), Ninh The Son(a), To Dao Cuong(a), Doan Thi Van(a), Pham Ngoc Khanh(a), Vu Thi Ha(a), Nguyen Cong Thuy Tram(b), Pham Quoc Long(a), Young Ho Kim(c)
    (a)Department of Bioactive Products, Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology (VAST), (b)Faculty of Biology-Environment, University of Education, University of Danang, (c)College of Pharmacy, Chungnam National University
    Chemical and Pharmaceutical Bulletin 64(8): 1230-1234, 2016.


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  • Reaction of Thymidine with Hypobromous Acid in Phosphate Buffer

    Toshinori Suzuki, Akihiko Kitabatake, Yuki Koide
    School of Pharmacy, Shujitsu University
    Chemical and Pharmaceutical Bulletin 64(8): 1235-1238, 2016.


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  • Antiproliferative Activity of Amathaspiramide Alkaloids and Analogs

    Jun Shimokawa(a), Koji Chiyoda(b), Hirotatsu Umihara(b), Tohru Fukuyama(a)
    (a)Graduate School of Pharmaceutical Sciences, Nagoya University, (b)Graduate School of Pharmaceutical Sciences, University of Tokyo
    Chemical and Pharmaceutical Bulletin 64(8): 1239-1241, 2016.


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  • Concise Synthesis of (2R,4R)-Monatin

    Yusuke Amino
    Institute for Innovation, Ajinomoto Co.,Inc.
    Chemical and Pharmaceutical Bulletin 64(8): 1242-1247, 2016.


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book
発行元:
日本薬学会
ISSN:
0009-2363
ISSN(オンライン):
1347-5223

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開始頁:
Medical Online English Site