バックナンバー:Chemical and Pharmaceutical Bulletin

Chemical and Pharmaceutical Bulletin
65巻 10号

  • Gibbs Free Energy of Hydrolytic Water Molecule in Acyl-Enzyme Intermediates of a Serine Protease : A Potential Application for Computer-Aided Discovery of Mechanism-Based Reversible Covalent Inhibitors

    Yosuke Masuda, Noriyuki Yamaotsu, Shuichi Hirono
    School of Pharmaceutical Sciences, Kitasato University
    Chemical and Pharmaceutical Bulletin 65(10): 889-892, 2017.


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  • Synthesis, Docking Simulation, Biological Evaluations and 3D-QSAR Study of 1,4-Dihydropyridines as Calcium Channel Blockers

    Tarek Fathy El-Moselhy(a), Peter Ayoub Sidhom(a), Eman Ahmed Esmat(a), Nageh Ahmed El-Mandy(b)
    (a)Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, (b)Department of Pharmacology, Faculty of Pharmacy, Tanta University
    Chemical and Pharmaceutical Bulletin 65(10): 893-903, 2017.


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  • Design, Synthesis, Antifungal Activity and Molecular Docking of Thiochroman-4-one Derivatives

    Yifan Zhong(a), Xiaoyan Han(a), Shengbin Li(a), Hui Qi(a), Yali Song(a),(b), Xiaoqiang Qiao(a),(b)
    (a)Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, (b)Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University
    Chemical and Pharmaceutical Bulletin 65(10): 904-910, 2017.


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  • Antileishmanial Thioureas : Synthesis, Biological Activity and in Silico Evaluations of New Promising Derivatives

    Gil Mendes Viana(a), Deivid Costa Soares(b), Marcos Vinicius Santana(c), Lilian Henriques do Amaral(a), Paloma Wetler Meireles(a), Raquel Pinto Nunes(a), Luiz Claudio Rodrigues Pereira da Silva(a), Lucia Cruz de Sequeira Aguiar(d), Carlos Rangel Rodrigues(e), Valeria Pereira de Sousa(a), Helena Carla Castro(c), Paula Alvarez Abreu(f), Plinio Cunha Sathler(a), Elvira Maria Saraiva(b), Lucio Mendes Cabral(a)
    (a)Universidade Federal do Rio de Janeiro, LabTIF, Faculdade de Farmacia, Ilha do Fundao, (b)Universidade Federal do Rio de Janeiro, Laboratorio de Imunobiologia das Leishmanioses, Instituto de Microbiologia Paulo de Goes, (c)Universidade Federal Fluminense, LABiEMol, Departamento de Biologia Celular e Molecular, Outeiro de Sao Joao Baptista, (d)Universidade Federal do Rio de Janeiro, Instituto de Quimica, Ilha do Fundao, (e)Universidade Federal do Rio de Janeiro, ModMolQSAR, Faculdade de Farmacia, Ilha do Fundao, (f)Laboratorio de Modelagem Molecular e Pesquisa em Ciencias Farmaceuticas, LaMCiFar. Universidade Federal do Rio de Janeiro-Campus Macae
    Chemical and Pharmaceutical Bulletin 65(10): 911-919, 2017.


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  • C-Homomorphinan Derivatives as Lead Compounds to Obtain Safer and More Clinically Useful Analgesics

    Kyoko Ishikawa(a), Fumika Karaki(a),(b), Kaoru Tayama(a), Eika Higashi(a), Shigeto Hirayama(a),(b), Kennosuke Itoh(a),(b), Hideaki Fujii(a),(b)
    (a)Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, (b)Medicinal Research Laboratories, School of Pharmacy, Kitasato University
    Chemical and Pharmaceutical Bulletin 65(10): 920-929, 2017.


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  • Microtropins Q-W, ent-Labdane Glucosides : Microtropiosides G-I, Ursane-Type Triterpene Diglucoside and Flavonol Glycoside from the Leaves of Microtropis japonica

    Saori Terazawa(a), Yuka Uemura(a), Yuka Koyama(a), Susumu Kawakami(b), Sachiko Sugimoto(a), Katsuyoshi Matsunami(a), Hideaki Otsuka(a),(b), Takakazu Shinzato(c), Masatoshi Kawahata(d), Kentaro Yamaguchi(d)
    (a)Graduate School of Biomedical and Health Sciences, Hiroshima University, (b)Faculty of Pharmacy, Yasuda Women's University, (c)Subtropical Field Science Center, Faculty of Agriculture, University of the Ryukyus, (d)Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Kagawa Campus
    Chemical and Pharmaceutical Bulletin 65(10): 930-939, 2017.


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  • Versatile Amine-Promoted Mild Methanolysis of 3,5-Dinitrobenzoates and Its Application to the Synthesis of Colorado Potato Beetle Pheromone

    Yumiko Yamano, Haruna Sasaki, Akimori Wada
    Department of Organic Chemistry for Life Science, Kobe Pharmaceutical University
    Chemical and Pharmaceutical Bulletin 65(10): 940-944, 2017.


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  • Rapid Analysis of DOXIL Stability and Drug Release from DOXIL by HPLC Using a Glycidyl Methacrylate-Coated Monolithic Column

    Arato Kimoto(a), Ayako Watanabe(b), Eiichi Yamamoto(c), Tatsuya Higashi(a), Masaru Kato(b)
    (a)Faculty of Pharmaceutical Sciences, Tokyo University of Science, (b)Graduate School of Pharmaceutical Sciences, The University of Tokyo, (c)Formulation Research, Pharmaceutical Science and Technology, Core Function Unit, Medicine Development Center, Eisai Co.,Ltd.
    Chemical and Pharmaceutical Bulletin 65(10): 945-949, 2017.


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  • Design, Synthesis and Antiproliferative Evaluation of Novel Disulfides Containing 1,3,4-Thiadiazole Moiety

    Shuai Zhang, Xiao-jia Liu, Rui Tang, Hai-xin Wang, Hai-ying Liu, Yu-ming Liu, Bao-quan Chen
    Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry & Chemical Engineering, Tianjin University of Technology
    Chemical and Pharmaceutical Bulletin 65(10): 950-958, 2017.


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  • Docetaxel-Loaded Lecithoid Nanoparticles with Enhanced Lung Targeting Efficiency and Reduced Systemic Toxicity : Developed by Solid Dispersion and Effervescent Techniques

    Li Zhang(a), Zhong-hong Liu(a), Xun-guan Cheng(a), Zhu Xia(b), Yu Liu(c), Yu Yu(a)
    (a)Research Laboratory of Medicinal Chemistry and Biomaterials, Chongqing Pharmaceutical Engineering Research Center, School of Pharmacy, Chongqing Medical University, (b)Department of Nuclear Medicine, The First Affiliated Hospital of Chongqing Medical University, (c)Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University
    Chemical and Pharmaceutical Bulletin 65(10): 959-966, 2017.


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  • Prediction of Dissolution Data Integrated in Tablet Database Using Four-Layered Artificial Neural Networks

    Kozo Takayama(a), Shota Kawai(b), Yasuko Obata(b), Hiroaki Todo(a), Kenji Sugibayashi(a)
    (a)Department of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University, (b)Department of Pharmaceutical Sciences, Hoshi University
    Chemical and Pharmaceutical Bulletin 65(10): 967-972, 2017.


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  • 5,6-Dihydropyrrolo[2,1-α]isoquinolines as Alternative of New Drugs with Cytotoxic Activity

    Rosa Maria Chavez-Santos(a), Paul Eduardo Reyes-Gutierrez(b), Ruben Omar Torres-Ochoa(a), Maria Teresa Ramirez-Apan(a), Roberto Martinez(a)
    (a)Instituto de Quimica, Universidad Nacional Autonoma de Mexico, Circuito Exterior, Ciudad Universitaria, (b)Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences
    Chemical and Pharmaceutical Bulletin 65(10): 973-981, 2017.


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  • Triplex- and Duplex-Forming Abilities of Oligonucleotides Containing 2'-Deoxy-5-trifluoromethyluridine and 2'-Deoxy-5-trifluoromethylcytidine

    Yuta Ito, Misaki Matsuo, Takashi Osawa, Yoshiyuki Hari
    Faculty of Pharmaceutical Sciences, Tokushima Bunri University
    Chemical and Pharmaceutical Bulletin 65(10): 982-988, 2017.


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  • Asymmetric Aldol/Vinylogous Aldol/Cyclization Reaction Using Phosphine Oxide Catalysts

    Nathan Ray Alim(a), Shiki Miyazaki(a), Yasushi Shimoda(a), Masaharu Sugiura(a), Makoto Nakajima(a), Shunsuke Kotani(a),(b)
    (a)Graduate School of Pharmaceutical Sciences, Kumamoto University, (b)Priority Organization for Innovation and Excellence, Kumamoto University
    Chemical and Pharmaceutical Bulletin 65(10): 989-993, 2017.


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  • Affinity Labeling with 4-Azidophthalimide (AzPI) : Relation between Labeling Rate and Fluorescence Intensity

    Kosuke Chiba, Yuichi Hashimoto, Takao Yamaguchi†
    Institute of Molecular and Cellular Biosciences, The University of Tokyo, †Present address : Graduate School of Pharmaceutical Sciences, Osaka University
    Chemical and Pharmaceutical Bulletin 65(10): 994-996, 2017.


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book
発行元:
日本薬学会
ISSN:
0009-2363
ISSN(オンライン):
1347-5223

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Medical Online English Site