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Alternatives to Animal Testing and Experimentation 18巻 suppl号

発行元
日本動物実験代替法学会
ISSN
1344-0411
ISSN（オンライン）
2185-4726
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開始頁
SL-S The 2013 EU ban of animal testing for cosmetics
Horst Spielmann
Freie Universitat Berlin, Inst. Pharmacy, Pharmacology & Toxicology
Alternatives to Animal Testing and Experimentation 18 (suppl) 100-101, 2013.
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SL-1 Nano-Safety Science and Sustainable Nanotechnology -Recent Progress-
Yasuo Tsutsumi
Grad. Sch. Pharm. Sci., Osaka Univ, NiBio
Alternatives to Animal Testing and Experimentation 18 (suppl) 102-102, 2013.
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SL-2 Application of iPSCs for in vitro recapitulating disease-phenotype: current status and future perspective
Junya Toguchida
Institute for Frontier Medical Sciences, Center for iPS Cell Research and Application, Department of Orthopaedic Surgery, Kyoto University Hospital, Kyoto University
Alternatives to Animal Testing and Experimentation 18 (suppl) 103-103, 2013.
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EL Role of alternative methods in safety evaluation of chemicals
Makoto Hayashi
Public Interest Incorporated Foundation, BioSafety Research Center (BSRC)
Alternatives to Animal Testing and Experimentation 18 (suppl) 104-104, 2013.
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OL New Developments in Basic Science and Alternatives to Animal Experiments
Koichi Imai
Osaka Dental University
Alternatives to Animal Testing and Experimentation 18 (suppl) 105-105, 2013.
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IS-1 Activities of EUSAAT, the Euroepan Society for Alternatives to Animal Testing
Horst Spielmann
Freie Universitat Berlin, Inst. Pharmacy, Pharmacology & Toxicology
Alternatives to Animal Testing and Experimentation 18 (suppl) 107-107, 2013.
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IS-2 International Alternatives Activities Benefit from Collaboration Between JSAAE and ASCCT
Rodger Curren
Institute for In Vitro Sciences
Alternatives to Animal Testing and Experimentation 18 (suppl) 108-108, 2013.
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IS-3 Current status on the alternative to animal experiments in Korea
Soon Young HAN1, Yong HEO2, Ki Hwan CHOI3, Won Keun SUNG3
1Korea National Institute of Health/ Korea Centers for Disease Control & Prevention, 2College of Natural Sciences, Catholic University of Daegu, 3KoCVAM, National Institute of Food & Drug Safety Research/Ministry of Food & Drug Safety
Alternatives to Animal Testing and Experimentation 18 (suppl) 109-109, 2013.
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IS-4 KeraSkin(TM)-VM: A novel reconstructed human epidermis model for skin irritation tests
Kyoung-Mi Jung1, Su-Hyon Lee2, Won-Hee Jang1, Haeng-Sun Jung2, Young-Ho Park1, SeungHyeok Seok3, Kyung-Min Lim4
1Amorepacific Co. R&D Center, 2Modern Cell & Tissue Technologies Inc, 3Department of Microbiology and Immunology, and Institute of Endemic Disease, Seoul National University Medical College, 4College of Pharmacology, Ewha Womans University
Alternatives to Animal Testing and Experimentation 18 (suppl) 110-110, 2013.
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IS-5 Activities of JSAAE
Hajime Kojima
JSAAE, NIHS
Alternatives to Animal Testing and Experimentation 18 (suppl) 111-111, 2013.
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S1-1 Significance of Controlling Quiescent Tumor Cell Populations in Cancer Thera py Including Radiation Therapy
Shin-ichiro Masunaga
Radiation Biology, Department of Radiation Life and Medical Science, Research Reactor Institute, Kyoto University
Alternatives to Animal Testing and Experimentation 18 (suppl) 113-113, 2013.
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S1-2 Radiation-induced cell kinetics detected by Fucci in multicellular spheroids
Masahiko Miura
Section of Oral Radiation Oncology, Tokyo Medical and Dental University
Alternatives to Animal Testing and Experimentation 18 (suppl) 114-114, 2013.
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S1-3 Analysis of the mechanisms of radiation sensitivity and responses using genetically-engineered mice
Hiroaki Honda
Department of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University
Alternatives to Animal Testing and Experimentation 18 (suppl) 115-115, 2013.
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S2-1 Three Rs and laboratory animal welfare legislation in EU
Anderson,D.B, Louhimies,S
European Commission
Alternatives to Animal Testing and Experimentation 18 (suppl) 117-118, 2013.
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S2-2 A notification or registration system of animal experiment facilities will raise and develop the level of life sciences study
Takashi Unno
Nishiwaki Lab, JCL Bioassay Corporation
Alternatives to Animal Testing and Experimentation 18 (suppl) 119-119, 2013.
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S2-3 The necessity of regulation the law for laboratory animals
Katsuhiro Ueda
The PetHoujuku (The Pet Law)
Alternatives to Animal Testing and Experimentation 18 (suppl) 120-120, 2013.
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S2-4 International Legal Framework for Laboratory Animal Welfare
Tsutomu Miki Kurosawa
Natsume Seisakusho Co. Ltd
Alternatives to Animal Testing and Experimentation 18 (suppl) 121-121, 2013.
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S3-1 Potential of human iPS cell-derived hepatic stem-like cells for drug toxicity test
Miho K Furue
Laboratory of Stem Cell Cultures, Department of Disease Bioresources Research, National Institute of Biomedical Innovation
Alternatives to Animal Testing and Experimentation 18 (suppl) 123-123, 2013.
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S3-2 Development of in vitro assays for drug discovery and toxicology using human iPS cell-derived neuronal cells
Yoshihiro Kanemura
Division of Regenerative Medicine, Institute for Clinical Research, Osaka National Hospital, National Hospital Organization
Alternatives to Animal Testing and Experimentation 18 (suppl) 124-124, 2013.
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S3-3 Non-labeled Real-time Evaluation using Cell Morphology Informatics
Risako Jouto1, Mika Okada1, Hiroto Sasaki2, Kei Kanie1, Mika Suga3, Kana Yanagihara3, Takayuki Fukuda3, Yasujiro Kiyota4, Miho Kusuda-Furue3, Ryuji Kato1
1Graduate School of Pharmaceutical Scicences, Nagoya University, 2Graduate School of Engineering, Nagoya University, 3Laboratory of Stem Cell Cultures, Department of Disease Bioresources Research National Institute of Biomedical Innovation, 4Nikon Corporation
Alternatives to Animal Testing and Experimentation 18 (suppl) 125-125, 2013.
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S4-1 Current problems on the safety control of new cosmetics
Ichiro Katayama
Department of Dermatology Course of Integrated Medicine, Graduate School of Medicine, Osaka University
Alternatives to Animal Testing and Experimentation 18 (suppl) 127-127, 2013.
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S4-2 Update on the regulation of Cosmetics and Quasi-Drugs regarding alternatives to animal testing
Hajime Kojima
Japanese Center for the Validation of Alternative Methods, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 18 (suppl) 128-128, 2013.
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S4-3 Approach for alternatives to animal testing of cosmetic ingredients
Shigenobu Hagino
Shiseido Research Center
Alternatives to Animal Testing and Experimentation 18 (suppl) 129-129, 2013.
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S4-4 Approaches of L'OREAL Group to Alternatives to Animal Experiments
Setsuko Jitsukawa
Scientific Direction, Research & Innovation Center, Nihon L'OREAL
Alternatives to Animal Testing and Experimentation 18 (suppl) 130-130, 2013.
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S4-5 Skin Sensitization Hazard Identification: Refinement of in chemico Alternative Methods
Petra Kern1, John Troutman2, Cindy Ryan2, Leslie Foertsch2, Frank Gerberick2
1Procter & Gamble Technology, Shunyi District, 2Procter & Gamble Company
Alternatives to Animal Testing and Experimentation 18 (suppl) 131-131, 2013.
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S5-1 In silico prediction of CYP-mediated drug metabolism
Yasushi Yamazoe1,2, Kazumi Ito1, Kouichi Yoshinari1
1Graduate School of Pharmaceutical Sciences, Tohoku University, 2Food Safety Commission, Cabinet Office, Government of Japan
Alternatives to Animal Testing and Experimentation 18 (suppl) 133-133, 2013.
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S5-2 Prediction of drug-drug interactions mediated by hepatic uptake transporters based on the physiologically-based pharmacokinetic models
Takashi Yoshikado1, Kenta Yoshida2, Kazuya Maeda2, Yuichi Sugiyama1
1Sugiyama Laboratory, RIKEN Innovation Center, 2Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo
Alternatives to Animal Testing and Experimentation 18 (suppl) 134-134, 2013.
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S5-3 Functional expression of human cells induced in engineered culture environment
Toshiyuki Kanamori, Kimio Sumaru, Shinji Sugiura, Taku Satoh, Fumiki Yanagawa
Drug Assay Device Team, Research Center for Stem Cell Engineering, National Institute of Advanced Industrial Science and Technology
Alternatives to Animal Testing and Experimentation 18 (suppl) 135-135, 2013.
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S5-4 Investigation of Substrate-Dependent Inhibition of Organic Anion Transporting Polypeptide 1B1 to Mitigate the Risk of False-Negative Prediction of Drug-Drug Interactions
Yoshitane Nozaki1, Saki Izumi1, Takafumi Komori1, Kazuya Maeda2, Hiroyuki Kusuhara2, Yuichi Sugiyama3
1Drug Metabolism and Pharmacokinetics Japan, Eisai Co., Ltd, 2Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, University of Tokyo, 3Sugiyama Laboratory, RIKEN Innovation Center
Alternatives to Animal Testing and Experimentation 18 (suppl) 136-136, 2013.
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S5-5 Proposal and Verification of in vitro/in silico Testing System for the Evaluation of Drug Transport and Metabolism in Liver
Seiichi Ishida
Division of Pharmacology, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 18 (suppl) 137-137, 2013.
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S6-1 Examination of hazard effect of nanomaterials -Role of inhalation study and intratracheal instillation study-
Yasuo Morimoto
Dept. of Occupational Pneumology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health
Alternatives to Animal Testing and Experimentation 18 (suppl) 139-139, 2013.
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S6-2 Development of a cultured alveolus epithelium model and its application in evaluation of health effects of nanoparticles
Yasuyuki Sakai
Department of Materials and Environmental Science, Institute of Industrial Science, University of Tokyo
Alternatives to Animal Testing and Experimentation 18 (suppl) 140-140, 2013.
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S6-3 Biomedical applications of phospholipid nanodiscs and photo-responsive nanomaterials
Tatsuya Murakami
Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University
Alternatives to Animal Testing and Experimentation 18 (suppl) 141-141, 2013.
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S6-4 Engineered Three-Dimensional Tissue Construction for Alternatives to Animal Experiments
Michiya Matsusaki, Mitsuru Akashi
Graduate School of Engineering, Osaka University
Alternatives to Animal Testing and Experimentation 18 (suppl) 142-142, 2013.
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S7-1 New LRI
Tatsuya Mizukoshi
Japan Chemical Industry Association
Alternatives to Animal Testing and Experimentation 18 (suppl) 144-144, 2013.
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S7-2 Global Trends of Chemical Safety Management and Industry Challenging
Fumiaki Shono
Japan Chemical Industry Association
Alternatives to Animal Testing and Experimentation 18 (suppl) 145-145, 2013.
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S7-3 A new system for the efficient assessment and test methods for the hazard of chemicals using mammalian artificial chromosome vectors
Mitsuo Oshimura
Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Sciences, Tottori University
Alternatives to Animal Testing and Experimentation 18 (suppl) 146-146, 2013.
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S7-4 A new assessment and test methods for the hazard of chemicals using the culture cells from luminescent transchromosomic mice
Tetsuya Ohbayashi
Division of Laboratory Animal Science, Research Center for Bioscience and Technology, Tottori University
Alternatives to Animal Testing and Experimentation 18 (suppl) 147-147, 2013.
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S7-5 Development of artificial chromosome vector-based luciferase assay system
Yoshihito Nakajima
National Institute of Advanced Industrial Science and Technology (AIST), Health Research Institute
Alternatives to Animal Testing and Experimentation 18 (suppl) 148-148, 2013.
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S7-6 in-vitro hepatotoxicity test to eliminate high-risk chemicals
Masako Tada
Chromosome Engineering Research Center, Tottori University
Alternatives to Animal Testing and Experimentation 18 (suppl) 149-149, 2013.
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S7-7 Development of new HTP screening in Vitro system for evaluating renal Toxicology by using kidney tissue stem cells
Shinji Kitamura
Department of Medicine and Clinical Science, Okayama University Graduate School
Alternatives to Animal Testing and Experimentation 18 (suppl) 150-150, 2013.
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S7-8 Development of a novel in-vitro neurotoxicity assay
Kumiko Kobayashi, Noriyuki Suzuki, Atsushi Kuwahara, Satoshi Ando, Koichi Saito
Sumitomo Chemical Co., Ltd
Alternatives to Animal Testing and Experimentation 18 (suppl) 151-151, 2013.
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W-1 History and Purpose of Alternatives to Animal Testing and Experimentation
Hideto Ariumi, Yuji Yoshiyama
Division of Community Pharmacy, Research and Education Center for Clinical Pharmacy, School of Pharmacy, Kitasato University
Alternatives to Animal Testing and Experimentation 18 (suppl) 153-153, 2013.
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W-2 How do we activate AATEX (Alternatives to Animal Testing and Experimentation) ?
Taku Matsushita
Department of Applied Life Science, Sojo University
Alternatives to Animal Testing and Experimentation 18 (suppl) 154-154, 2013.
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W-3 Measures to promote AATEX activities
Tetsuya Hasegawa
Laboratory of Drug Metabolism and Pharmacokinetics, Faculty of Pharmaceutical Sciences, Josai International University
Alternatives to Animal Testing and Experimentation 18 (suppl) 155-155, 2013.
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W-4 Social duties in future of the AATEX
Koichi Imai
Osaka Dental University
Alternatives to Animal Testing and Experimentation 18 (suppl) 156-156, 2013.
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LSB-1 Implementation of practical 3Rs with NATSUME RAT which is designed for animal handling model International Trend in Laboratory Animal Welfare
Tsutomu Miki Kurosawa
Osaka University Medical School
Alternatives to Animal Testing and Experimentation 18 (suppl) 158-158, 2013.
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M-1 Development of a cell-based model of the retina within a microfluidic device
Hirokazu Kaji1, Toshinori Fujie2, Syuntaro Ito1, Nobuhiro Nagai3, Kuniaki Nagamine1, Matsuhiko Nishizawa1, Toshiaki Abe3
1Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, 2WPI-Advanced Institute for Materials Research, Tohoku University, 3United Center for Advanced Research and Translational Medicine, Tohoku University Graduate of Medicine
Alternatives to Animal Testing and Experimentation 18 (suppl) 160-160, 2013.
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M-2 Establishment of in vitro circadian clock system for evaluation of the mechanism for malignant transformation of cells
Satoru Koyanagi
Department of Pharmaceutics, Graduate School of Pharmaceutical Sciences, Kyushu University
Alternatives to Animal Testing and Experimentation 18 (suppl) 161-161, 2013.
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M-3 Search for new candidate drugs for Progressive Familial Intrahepatic Cholestasis Type 2 (PFIC2)
Hisamitsu Hayashi
Graduate School of Pharmaceutical Sciences, Univ. of Tokyo
Alternatives to Animal Testing and Experimentation 18 (suppl) 162-162, 2013.
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P-1 Skin sensitization study from only animal data by structure-toxicity relationships (QSTR) approach
Kazuhiro Sato1, Kohtaro Yuta2, Yukinori Kusaka1
1Department of Environmental Health, School of Medicine, University of Fukui, 2In Silico Data
Alternatives to Animal Testing and Experimentation 18 (suppl) 164-164, 2013.
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P-2 Hazard Evaluation Support System (HESS)II-Proposition of in vitro assays use ful for predicting repeated-dose toxicity of chemical substances-
Takashi Yamada1, Yushiro Tanaka1, Ryuichi Hasegawa1, Yuki Sakuratani1, Jun Yamada1, Kouichi Yoshinari2, Yasushi Yamazoe2, Atsushi Ono3, Akihiko Hirose3, Makoto Hayashi4
1Chemical Management Center, National Institute of Technology and Evaluation, 2Graduate School of Pharmaceutical Sciences, Tohoku University, 3Biological Safety Research Center, National Institute of Health Sciences, 4BioSafety Research Center
Alternatives to Animal Testing and Experimentation 18 (suppl) 165-165, 2013.
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P-3 Trial for development of in vitro risk assessment model for skin sensitization using artificial neural network analysis (I) -the analysis using in vitro tests-
Morihiko Hirota1, Tomomi Atobe1, Takao Ashikaga1, Hirokazu Kouzuki1, Setsuya Aiba2
1Shiseido Research Center, 2Department of Dermatology, Tohoku University Graduate School of Medicine
Alternatives to Animal Testing and Experimentation 18 (suppl) 166-166, 2013.
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P-4 Trial for development of in silico risk assessment model for skin sensitization using artificial neural network analysis (II) -the analysis using in silico-
Tomomi Atobe, Morihiko Hirota, Takao Ashikaga, Hirokazu Kouzuki
Shiseido Research Center
Alternatives to Animal Testing and Experimentation 18 (suppl) 167-167, 2013.
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P-5 Predictive Genotoxicity in Silico
Maki Aiba, Morihiko Hirota, Kouzuki Hirokazu
Shiseido Research Center
Alternatives to Animal Testing and Experimentation 18 (suppl) 168-168, 2013.
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P-6 Research aimed at integration of in silico assessment of toxicity to the Alternatives to Animal Experiments (1)
Kohtaro Yuta
In Silico Data, Ltd
Alternatives to Animal Testing and Experimentation 18 (suppl) 169-169, 2013.
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P-7 Comparison of two methods for constructing 95% confidence intervals of ratios of mean values obtained using alternative assays
Azusa Mori, Maruya Aoi, Mayumi Kobayashi, Takashi Omori
DOSHISHA UNIVERSITY
Alternatives to Animal Testing and Experimentation 18 (suppl) 170-170, 2013.
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P-8 Relationship between IC50 and ID50 in Hand1-Luc EST assay
Mayumi Kobayashi1, Noriyuki Suzuki2, Le Coz Florian2, Hirohisa Nagahori2, Koichi Saito2, Azusa Mori1, Aoi Maruyama1, Takashi Omori1
1DOSHISHA UNIVERSITY, 2Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd
Alternatives to Animal Testing and Experimentation 18 (suppl) 171-171, 2013.
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P-9 Evaluation of Local Lymph Node Assay as an Alternative Method for skin Sensitization Potential In CBA/N mice
Yujeong Lee1, Mi-Sook Jung1, Eun-Young Jeon1, Heung-Mo Bae1, Sang-Koo Lee1, Jong-Koo Kang2
1Pharmacology Department Efficacy Division, Biotoxtech Co., Ltd, 2Chung-buk National University
Alternatives to Animal Testing and Experimentation 18 (suppl) 172-172, 2013.
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P-10 Development of a method to predict skin sensitisation using a novel Lys derivative and Cys derivative
Masaharu Fujita1, Toshihiko Kasahara1, Yoshiro Jinbo2, Takanori Hioki1
1Safety Evaluation Center, Environment & Quality Management Div., CSR Div., FUJIFILM Corporation, 2Synthetic Organic Chemistry Laboratories, Research & Development Management Headquarters, FUJIFILM Corporation
Alternatives to Animal Testing and Experimentation 18 (suppl) 173-173, 2013.
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P-11 Predictive performance of human cell line activation test (h-CLAT) for skin sensitizing potential of lipophilic chemicals
Osamu Takenouchi1, Yasutaka Kuroda1, Kazutoshi Saito1, Masaaki Miyazawa1, Takao Ashikaga2, Hitoshi Sakaguchi1
1Kao Corporation, 2Shiseido Corporation
Alternatives to Animal Testing and Experimentation 18 (suppl) 174-174, 2013.
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P-12 The development of LLNA:DAE method and the results of intra-lavolatory validation
Kunihiko Yamashita1, Shinsuke Shinoda2, Saori Hagiwara2, Hiroshi Itagaki3
1Daicel Corporation, 2Drug Safety Testing Center Co., Ltd, 3Yokohama National University
Alternatives to Animal Testing and Experimentation 18 (suppl) 175-175, 2013.
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P-13 Development of alternative skin sensitization test model utilizing a collagen vitrigel membrane chamber (bottom side exposure method)
Tadashi Uchino1, Kumiko Shimizu1, Toshiaki Takezawa2, Kunihiko Yamashita3, Hajime Kojima1, Takumi Akiyama1, Yoshiaki Ikarashi1
1National Institue of Health Sciences, 2National Institute of Agrobiological Sciences, 3Daicel Corporation
Alternatives to Animal Testing and Experimentation 18 (suppl) 176-176, 2013.
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P-14 An inter-laboratory validation study and creation of a dataset of IL-8 Luc assay
Yotaka Kimura1, Chizu Fujimura1, Mika Watanabe2, Rumiko Saito2, 3, Noriyuki Suzuki4, Tomoko Iwaki5, Kohji Yamakage2, Koichi Saitou4, Yoshihiro Nakajima5, Yoshihiro Ohmiya6, Ayako Sakai2, Aoi Maruya7, Takashi Omori7, Shojiro Yamazaki8, Hajime Kojima9, Noriho Tanaka8, Setsuya Aiba1
1Department of Dermatology, Tohoku University Graduate School of Medicine, 2Hatano Research Institute, Food and Drug Safety Center, 3Tohoku Medical Megabank Organization, Tohoku University, 4Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd, 5Health Research Institute, Advanced Industrial Science and technology, 6Biomedical Research Institute, Advanced Industrial Science and Technology, 7Doshisha University, 8Organization for Tottori Industrial Promotion, 9National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 18 (suppl) 177-177, 2013.
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P-15 A proposal of a criterion incorporating variation of measurement of the IL-8 Luc assay
Aoi Maruya1, Setsuya Aiba2, Yutaka Kimura2, Mika Watanabe3, Noriyuki Suzuki4, Tokomo Iwaki5, Kohji Yamakage3, Koichi Saito4, Yoshihiro Nakajima5, Yoshihiro Ohmiya6, Shojiro Yamazaki3, Hajime Kojima7, Noriho Tanaka3, Mayumi Kobayashi1, Azusa Mori1, Takashi Omori1
1DOSISYA UNIVERSITY, 2Department of Dermatology, Tohoku University Graduate School of Medicine, 3Hatano Research Institute, Food and Drug Safety Center, 4Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd, 5Health Research Institute, Advance Industrial Science And Technology, 6Biomedical Research Institute, Advanced Industrial Science And Technology, 7National Institute of Health Science
Alternatives to Animal Testing and Experimentation 18 (suppl) 178-178, 2013.
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P-16 Embryonic stem cell test using human iPS cells-thalidomide embryotoxicity
Nobuo Aikawa1, Kunisato Atsushi2, Takaba Katsumi1, Kenji Nagao2, Kinya Ohgami1, Hideaki Kusaka1
1Drug Discovery Research Laboratories, Fuji Research Park, Research Division, Kyowa Hakko Kirin Co., Ltd, 2Biologics Research Laboratories, Tokyo Research Park, Research Division, Kyowa Hakko Kirin Co., Ltd
Alternatives to Animal Testing and Experimentation 18 (suppl) 179-179, 2013.
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P-17 The effect on the differentiation of ES cells in the case of two feeder cells derived from the oviduct or uterus
Koichi Imai1, Kazuhiko Suese2, Yoshitomo Honda3, Hiromasa Takashima4
1Department of Biometerials, Osaka Dental University, 2Osaka Dental University. School of Dental Technician and Hygienist, 3Institute of Dental Research, Osaka Dental University, 4Ina Research Inc
Alternatives to Animal Testing and Experimentation 18 (suppl) 180-180, 2013.
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P-18 Angiogenesis of dental gold-silver-palladium alloy component ions used by in vitro angiogenesis kit
Koichi Imai1, Tetsunari Nishikawa2, Tomoharu Okamura2, Akio Tanaka2, Yoshitomo Honda3, Kazuhiko Suese4
1Department of Biomaterials, Osaka Dental University, 2Department of Oral Pathology, Osaka Dental University, 3Institute of Dental Research, Osaka Dental University, 4Osaka Dental University. School of Dental Technician and Hygienist
Alternatives to Animal Testing and Experimentation 18 (suppl) 181-181, 2013.
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P-19 In vitro evaluation of the embryotoxic potency of amorphous nanosilica
Yasuo Yoshioka1, Toshinobu Ogura1, Tashiro Katsuhisa2, Kenji Kawabata1,2, Hiroyuki Mizuguchi1,2,3, Kazuma Higashisaka1, Yasuo Tsutsumi1,2,3
1Graduate School of Pharmaceutical Sciences, Osaka University, 2National Institute of Biomedical Innovation, 3MEI center, Osaka University
Alternatives to Animal Testing and Experimentation 18 (suppl) 182-182, 2013.
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P-20 Development of high-dispersibility nanocrystals of calcined hydroxyapatite
Masahiro Okada1, Yuko Omori2, Shoji Takeda1, Naoyuki Matsumoto2
1Department of Biomaterials, Osaka Dental University, 2Department of Orthodontics, Osaka Dental University
Alternatives to Animal Testing and Experimentation 18 (suppl) 183-183, 2013.
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P-21 Evaluation of nanoparticle permeation using a cultured pulmonary alveolar tissue model and a numerical model
Takuya Aoyama1, Kokoro Iwasawa1, Naohide Shinohara2, Guihua Zhang2, Masashi Gamo2, Yasuyuki Sakai1
1Institute of Industrial Science, the University of Tokyo, 2The National Institute of Advanced Industrial Science and Technology
Alternatives to Animal Testing and Experimentation 18 (suppl) 184-184, 2013.
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P-22 Preparation of transparent and low-crystallized hydroxyapatite via low temperature process
Mayo Uehira1, Keiko Fujiwara1, Naoyuki Matsumoto1, Shoji Takeda2, Masahiro Okada2
1Department of Orthodontics, Osaka Dental University, 2Department of Biomaterials, Osaka Dental University
Alternatives to Animal Testing and Experimentation 18 (suppl) 185-185, 2013.
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P-23 Study of interaction between cancer spheroid formed by Hanging Drop Method and human mesenchymal stem cells - Application od highly efficient inernalization of quantum dots to cells-
Toshimasa Uemura1, Mika Pietilae2, Petri Lehankari2, Sunil Kaul3, Renu Wadhwa3
1Nanosystem Research Institute, AIST, 2University of Oulu, 3Biomedical Research Institute, AIST
Alternatives to Animal Testing and Experimentation 18 (suppl) 186-186, 2013.
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P-24 Development of an in vitro method for neurotoxicity using neuronal cell derived from mouse embryonic stem cells
Kumiko Kobayashi, Noriyuki Suzuki, Atsushi Kuwabara, Satoshi Ando, Kayo Sumida, Kouichi Saito
Sumitomo Chemical Co., Ltd
Alternatives to Animal Testing and Experimentation 18 (suppl) 187-187, 2013.
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P-25 Novel biological assay device of neurologic cells with thin-layer gel system composed of ECM-modelized matrix
Hideyuki Mizumachi, Hiroyuki Ijima
Department of Chemical Engineering, Faculty of Engineering, Graduate School, Kyushu University
Alternatives to Animal Testing and Experimentation 18 (suppl) 188-188, 2013.
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P-26 Development of a bioassay using Neuro2a cell for marine toxins
Akiko Hasegawa, Mizuna Nakamura, Mami Hata, Teruo Yamashita, Hiroko Minagawa
Laboratory of Medical Zoology, Department of Microbiorogy and Medical Zoology, Aichi Prefectural Institute of Public Health
Alternatives to Animal Testing and Experimentation 18 (suppl) 189-189, 2013.
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P-27 A genotoxicity test based on p53R2 gene expression in human cells (NESMAGET, Part16). -Species differences in a metabolic activation-
Taisei Mizota, Mina Itoh, Katsutoshi Ohno, Toshihiro Yamada
Food Safety Research Institute, Nissin Foods Holdings Co., Ltd
Alternatives to Animal Testing and Experimentation 18 (suppl) 190-190, 2013.
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P-28 Modification of the 3T3 NRU photo-toxicity test conditions for the evaluation of poorly water-soluble substances
Akemi Toyoda1, Maki Sugiyama1, Seiichiro Furihata1, Keiji Nishizumi1, Hiroshi Itagaki2
1Quality Reseach Department, POLA Chemical Industries, INC, 2Yokohama National University
Alternatives to Animal Testing and Experimentation 18 (suppl) 191-191, 2013.
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P-29 Refinement of phototoxicity test using 3D model
Sakiko Aizawa, Mika Tsurumaki, Noriyasu Imai, Takuji Masunaga
Fundamental Research Laboratories, KOSE Corporation
Alternatives to Animal Testing and Experimentation 18 (suppl) 192-192, 2013.
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P-30 In vitro photosafety assessment of cosmetic ingredients with use of the ROS assay
Gen Suzeki1, Masashi Kato1, Morihiko Hirota2, Hayato Nishida2, Hirokazu Kouzuki2, Satomi Onoue1, Shizuo Yamada1
1Department of Pharmacokinetics and Pharmacodynamics, Graduated School of Pharmaceutical Sciences, University of Shizuoka, 2Siseido Research Center
Alternatives to Animal Testing and Experimentation 18 (suppl) 193-193, 2013.
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P-31 Peer review of the Japanese validation study of the ROS in vitro phototoxicity assay for ICH
Hajime Kojima1, W Stokes2, I Horii3, BH Kim4, Horst Spielmann5
1National Institute of Health Sciences, 2North Carolina State University, 3Pfizer, 4Keimyung University, 5Panel Chairman, Freie Universitat Berlin
Alternatives to Animal Testing and Experimentation 18 (suppl) 194-194, 2013.
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P-32 Development of fluorescent reactive oxygen species (fROS) assay for photosafety evaluation
Hiroto Ohtake, Kato Masashi, Onoue Satomi, Shizuo Yamada
School of Pharmaceutical Sciences, University of Shizuoka
Alternatives to Animal Testing and Experimentation 18 (suppl) 195-195, 2013.
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P-33 Enzymatic reactive oxygen species assay (eROS assay) for evaluating the phototoxic risk of drug metabolites in the early stage of drug discovery.
Masashi Kato, Hiroto Ohtake, Satomi Onoue, Shizuo Yamada
Department of Pharmacokinetics and Pharmacodynamics, Graduate School of Integrated Pharmaceutical and Neutrition Sciences, University of Shizuoka
Alternatives to Animal Testing and Experimentation 18 (suppl) 196-196, 2013.
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P-34 Study on the evaluation of a three-dimensional reconstructed human skin model using an Atomic Force Microscope
Teiko Seki1, Chiaki Takeuchi2, Sanae Matsuda2, Miku Kawama2, Tsukimura Wataru1, Hiroya Seki3, Masayoshi Hisama2, Norihiko Itoh1,4,5
1Dainichiseika-Donated Chair of Research Division for Innovative Biomaterials, Center for Biological Resources and Informatics, Tokyo Institute of Technology, 2Central Research Center, TOYO BEAUTY Co., Ltd, 3Chemical Resources Laboratory, Tokyo Institute of Technology, 4Tottori University Veterinary Medical Center, 5Department of Ophthalmology, Tokyo Medical University
Alternatives to Animal Testing and Experimentation 18 (suppl) 197-197, 2013.
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P-35 Evaluation of keratinization using the reconstructed human epidermal model
Takao Hanada, Yuichi Itahara, Masakazu Kato, Masukazu Inoie, Ken-ichiro Hata
Japan Tissue Engineering Co., Ltd
Alternatives to Animal Testing and Experimentation 18 (suppl) 198-198, 2013.
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P-36 Usefulness of Strat-M(TM) for prediction of human skin permeation of chemical compounds
Sayumi Kanai, Wesam R Kadhum, Konstanty Wierzba, Hiroaki Todo, Kenji Sugibayashi
Faculty of Pharmaceutical Sciences, Josai University
Alternatives to Animal Testing and Experimentation 18 (suppl) 199-199, 2013.
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P-37 Development of primary skin irritation testing strategy using monolayer culture system
Shigeyuki Nomura, Yuichiro Goto, Koko Tanigawa, Noriyasu Imai, Takuji Masunaga
Fundamental Research Laboratories, KOSE Corporation
Alternatives to Animal Testing and Experimentation 18 (suppl) 200-200, 2013.
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P-38 Study of in vitro skin irritation test targeted for the sensitive skin (Part 3)
Hidefumi Ikeda, Hideki Nishiura
R&D Basic Research, Nihon Kolmar Co., Ltd
Alternatives to Animal Testing and Experimentation 18 (suppl) 201-201, 2013.
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P-39 Special Committee's Report -Alternative Primary Irritation Test-
Mriko Sugiyama, Noriyasu Imai, Takashi Omori, Shigenobu Hagino, Hiroaki Todo, Akemi Toyoda, Kenji Sugibayashi
Special committee on alternative primary irritation test, Japanese Society of Alternatives to Animal Experiments
Alternatives to Animal Testing and Experimentation 18 (suppl) 202-202, 2013.
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P-40 Predicting Ocular Irritation of Surfactants Using the Bovine Corneal Opacity and Permeability Assay
Jackie E.Bader, Kimberly G.Norman, Hans Raabe
Institute for In Vitro Sciences, Inc., Gaithersburg
Alternatives to Animal Testing and Experimentation 18 (suppl) 203-203, 2013.
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P-41 Evaluation of the Eye Stinging Potential of Baby Shampoos by Assessing TRPV 1 Channel Activity
Anna Forsby1, Kimberly Norman2, Lindsay Krawiec2, Johanna EL Andaloussi-Lilja1, Jessica Lundqvist1, Beata Wojcik3, Vincent Walczak3, Rodger Curren2, Katharine Martin3, Neena Tierney3
1Department of Neurochemistry, the Arrhenius Laboratories for Natural Science, Stockholm University, 2Institute for In Vitro Sciences, Inc, 3Johnson & Johnson Consumer and Personal Products Worldwide
Alternatives to Animal Testing and Experimentation 18 (suppl) 204-204, 2013.
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P-42 Validation and Application of the KeratinoSens Assay, a Novel In Vitro Skin Sensitization Assay
Hans Raabe1, Nicole Barnes1, Allison Hilberer1, Andreas Natsch2, Kimberly Norman1, Nathan Wilt1, Rodger Curren1
1Institute for In Vitro Sciences, 2Givaudan Schweiz AG
Alternatives to Animal Testing and Experimentation 18 (suppl) 205-205, 2013.
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P-43 Guidance on the Implementation of new laboratory animal welfare legislation in EU
Anderso B David, Louhimies Susanna
European Commission
Alternatives to Animal Testing and Experimentation 18 (suppl) 206-206, 2013.
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P-44 Construction of three-dimensional reconstructed corneal model by using immortalized human corneal epithelial cell line (iHCE-NY)
Yoshinao Kato1, Naoki Yamamoto1, Atsushi Sato1, Satoru Nakata1, Hajime Kojima3
1Research Institutes, Nippon Menard Cosmetic Co., Ltd, 2Fujita Health University Joint Research Laboratory, 3National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 18 (suppl) 207-207, 2013.
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P-45 Immunohistochemical study of a new corneal toxicity method using cultured porcine corneal tissues
Hiroki Takahashi1, Kazuki Tajima1, Shunsuke Kato2, Takaaki Hattori1, Norihiko Ito1,3, Hitoshi Goto1
1Department of Ophthalmology, Tokyo Medical University, 2Tokyo University of Pharmacy and Lifesciences, 3Dainichiseika-Donated Chair of Research Division for Innovative Biomaterials, Tokyo Institute of Technology
Alternatives to Animal Testing and Experimentation 18 (suppl) 208-208, 2013.
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P-46 Effects of alternative concentrations and exposure times of the test article in the bovine corneal opacity and permeability (BCOP) test method
Masatoshi Furukawa1, Takashi Sakakibara1, Masumi Rokukawa1, Kouta Itoh1, Satoshi Sasaki1, Takeo Hiraga2, Hajime Kojima3, Masao Matsuura1
1Safety Research Institute for Chemical Compounds Co., Ltd, 2Department of Veterinary Medicine, Rakuno Gakuen Univercity, 3National Institute of Health Science
Alternatives to Animal Testing and Experimentation 18 (suppl) 209-209, 2013.
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P-47 An international validation study: in vitro alternative method for eye irritation using SIRC-CVS cytotoxicity test (II)
Takashi Omori1, Momoko Sunouchi2, Hidefumi Ikeda4, Kaori Nakamura3, Mi-Sook Jung5, Kohji Yamagkage6, Shigenobu Hagino7, Hajime Kojima2
1Epidemiolotgy & Biostatistics Laboratory, Faculty of Culture and Information Science, Doshisha University, 2JaCVAM, NIHS, 3BoZo Research Center Inc., Tokyo Laboratory, 4Nihon Kolmar, Co., Ltd., R&D, 5Biotoxtech Co. Ltd, 6Hatano Research Institute, FDSC, 7Shiseido Research Center
Alternatives to Animal Testing and Experimentation 18 (suppl) 210-210, 2013.
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P-48 Pre-validation study of Vitrige-EIT (Eye Irritancy Test) method
Hajime Kojima1, Nicole Kleinstreuer3, Chae-Hyung Lim4, Takashi Sozu5, Mika Watanabe6, Takeru Niitsuma7, Kunihiko Yamashita7, Takayuki Fukuda8, Noriko Yamaguchi8, Sho Fujiwara8, Hiroyuki Yamaguchi2,9, Toshiaki Takezawa2
1National Institute of Health Sciences, 2National Institute of Agrobiological Sciences, 3ILS/NICEATM/ICCVAM, Research Triangle Park, 4KOCVAM/MFDS, 5Kyoto University, 6Hatano Research Institute, Food and Drug Safety Center, 7Daicel Corporation, 8Bozo Research Center Inc, 9Kanto Chemical Co., Inc
Alternatives to Animal Testing and Experimentation 18 (suppl) 211-211, 2013.
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P-49 Development of metabolism-integrated in vitro reporter gene assay
Kouchi Yoshinari, Hiroyuki Nakajima, Chese Noomote
Graduate School of Pharmaceutical Sciences, Tohoku University
Alternatives to Animal Testing and Experimentation 18 (suppl) 212-212, 2013.
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P-50 Effects of sandwich-culture and co-culture systems on the culture method activating hepatic function of HepG2 cells utilizing a collagen vitrigel membrane chamber
Ayumi Oshikata1, Seiichi Ishida2, Toshiaki Takezawa1
1Division of Animal Sciences, National Institute of Agrobiological Sciences, 2Division of Pharmacology, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 18 (suppl) 213-213, 2013.
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P-51 Long term culture of human hepatocytes using hollow fiber type three dimensional culture module and its application to the evaluation of drug toxicity
Taku Matsushita1, Takaaki Ishii1, Nozomu Shibuya2, Mamiko Yanagi2, Kenjiro Ikuta2, Kouji Kusaka2
1Department of Applied Life Science, Sojo University, 2MITSUBISHI RAYON CO., LTD., YOKOHAMA RESEARCH LABORATORIES
Alternatives to Animal Testing and Experimentation 18 (suppl) 214-214, 2013.
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P-52 Hazard Evaluation Support System Integrated Platform (HESS) I -Evaluation of sensitivity to address hepatotoxicity-
Junko Ohuchi1, Toshio Kasamatsu1, Yuki Sakuratani2, Takashi Yamada2, Naohiro Nishiyama1, Jun Yamada2
1Safety Science Research, Kao Corporation, 2Chemical Management Center, National Institute of Technology and Evaluation (NITE)
Alternatives to Animal Testing and Experimentation 18 (suppl) 215-215, 2013.
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P-53 Dual-color fluorescent imaging of human CYP3A4 and CYP3A7 expression in human hepatic carcinoma cell lines HepG2 and HepaRG
Saori Tsuji1, Fumihiko Kawamura2, Musashi Kubiura2, Ayaka Hayashi2, Tetsuya Ohobayashi3, Yasuhiro Kazuki2,4, Mitsuo Oshimura2,4, Masako Tada4
1Bio Frontier Project Promotion Section Organization for Tottori Industrial Promotion, 2Division of Molecular Genetics and Biofunction, Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, 3Division of Laboratory Animal Science, Research Center for Bioscience and Technology, Tottori University, 4Chromosome Engineering Research Center, Tottori University
Alternatives to Animal Testing and Experimentation 18 (suppl) 216-216, 2013.
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P-54 Spheroid co-culture of rat hepatocytes with 3T3 cells using microwell chip
Yuki Goto, Yukiko Yoshiura, Kouji Nakazawa
Department of Life and Environment Eng., The University of Kitakyushu
Alternatives to Animal Testing and Experimentation 18 (suppl) 217-217, 2013.
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P-55 Evaluation of Hepatic Function of Mouse Hepatocyte Spheroids on Cell-able(TM) Plates with Various Feeder Cells
Shigenobu Wakuri1, Rumiko Saito1, 2, Kiyoshi Sasaki1, Maiko Gondo1, Nobuko Endo1, Hajime Sui1, Koji Yamakage1
1Lab. of Cell Carcinogenesis, Hatano Institute, Food and Drug Safety Center, 2Department of Integrative Genomics, Tohoku Medical Megabank Organization (ToMMo), Tohoku University
Alternatives to Animal Testing and Experimentation 18 (suppl) 218-218, 2013.
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P-56 Stabilization of hepatocyte heterospheroids by co-culture method and their metabolic function
Masako Nagamura1, Saya Okimura1, Kohei Sasaki1, Satoshi Suzuki2, Hidenori Otsuka1
1Department of Chemical Sciences and Technology, Graduate School of Chemical Science and Technology, Tokyo University of Science, 2Human and Animal Bridging (HAB) Research Organization
Alternatives to Animal Testing and Experimentation 18 (suppl) 219-219, 2013.
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P-57 Newly established Semi-IPN Gel System for Long-term Stabilization of Primary Hepatocytes
Yuki Takahashi, Masako Nagamura, Saya Okimura, Hidenori Otsuka
Department of Chemical Sciences and Technology, Graduate School of Chemical Science and Technology, Tokyo University of Science
Alternatives to Animal Testing and Experimentation 18 (suppl) 220-220, 2013.
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P-58 Development of in vitro developmental toxicity test including hepatic metabolism activity
Kazuaki Nakamura, Kazuko Aizawa, Naoko Hori, Akito Tanoue
Department of Pharmacology, National Research Institute for Child Health and development
Alternatives to Animal Testing and Experimentation 18 (suppl) 221-221, 2013.
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P-59 Functions and gene expressions of cultured-primary rat hepatocytes on oxygen-permeable membranes under physiological oxygen concentrations
Wenjin Xiao1, Hitoshi Matsui2, Marie Shinohara1, Kikuo Komori1, Tomoharu Osada2, Yasuyuki Sakai1
1Institute of Industrial Science (IIS), University of Tokyo, 2Mitsubishi Chemical Medience Corporation
Alternatives to Animal Testing and Experimentation 18 (suppl) 222-222, 2013.
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P-60 A hierarchical co-culture for mimicking liver-specific microvasculature to model liver-specific metastasis
Mohammad Mahfuz Chowdhury1, Mathieu Danoy Danoy2, Shohei Kaneda1, Teruo Fujii1, Yasuyuki Sakai1
1Institute of Industrial Science, University of Tokyo, 2University of Lille 1
Alternatives to Animal Testing and Experimentation 18 (suppl) 223-223, 2013.
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P-61 Effects of kanka(KNK) on cultured rat embryos
Atsushi Yokoyama1, Masaharu Akita2
1Kanagawa Life-Sciense Res, 2Kamakura Woman's University
Alternatives to Animal Testing and Experimentation 18 (suppl) 224-224, 2013.
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P-62 Effects of isokuersitorine(IKS) on cultured rat embryos
Atsushi Yokoyama1, Masaharu Akita2
1Kanagawa Life-Sciense Res, 2Kamakura Woman's University
Alternatives to Animal Testing and Experimentation 18 (suppl) 225-225, 2013.
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P-63 Rapid and quantitative efficacy prediction of bioactive compound for skin turnover with toxicity at physiological concentration - Evaluation within 1 h -
Toshihiro Ona1, Junko Shibata2
1Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 2OK Lab. Corporation, Cell BET Division
Alternatives to Animal Testing and Experimentation 18 (suppl) 226-226, 2013.
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P-64 Exposure experiment for water-insoluble chemicals to cultured cell line
Kazuto Narita1, Yuujin Ishihara1, Hajime Kojima2, Hiroshi Itagaki1
1Department of Materials Science and Engineering, Yokohama National University, 2National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 18 (suppl) 227-227, 2013.
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P-65 Osteogenic effect of novel media for mouse and human mesenchymal stem cells
Yoshitomo Honda1, Yoshiya Hashimoto2, Koichi Imai2, Shoji Takeda2
1Institute of Dental Research, Osaka Dental University, 2Department of Biomaterials, Osaka Dental University
Alternatives to Animal Testing and Experimentation 18 (suppl) 228-228, 2013.
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P-66 The evaluation of Multi-Immuno Tox Assay as a high throughput immunotoxicity assay
Yutaka Kimura1, Chizu Fujimura1, Yoshihiro Ohmiya2, Setsuya Aiba1
1Department of Dermatology, Tohoku University Graduate School of Medicine, 2Biomedical Research Institute, Advanced Industrial Science and Technology
Alternatives to Animal Testing and Experimentation 18 (suppl) 229-229, 2013.
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P-67 Application of GFP-transgenic silkworm for an animal model of drug-induced tissue injury
Yoshinori Inagaki1, Yasuhiko Matsumoto1, Yasue Matsutani2, Takuya Tsubota3, Hideki Sezutsu3, Kazuhisa Sekimizu1,2
1Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2Genome Pharmaceuticals Institute Co., Ltd, 3Transgenic Silkworm Research Unit, National Institute of Agrobiological Sciences
Alternatives to Animal Testing and Experimentation 18 (suppl) 230-230, 2013.
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P-68 Development of an alternative method of acute oral toxicity tests using silkworm Part2
Takuya Sugita1, Yutaka Yamamoto1, Takuro Ueki1, Satoshi Nishida2, Hiroshi Hamamoto3, Yasuhiko Matsumoto3, Kazuhisa Sekimizu2,3, Hidenobu Okumura1
1Noevir Co., Ltd, 2Genome Pharmaceuticals Institute Co., Ltd, 3Graduate School of Pharmaceutical Sciences, The University of Tokyo
Alternatives to Animal Testing and Experimentation 18 (suppl) 231-231, 2013.
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P-69 Effects of acetylcholine on the H2O2-induced reduction of connexin43 protein in rat cardiomyocytes
Hideto Ariumi, Yuma Ishizaki, Yuji Yoshiyama
Division of Community Pharmacy, Research and Education Center for Clinical Pharmacy, School of Pharmacy, Kitasato University
Alternatives to Animal Testing and Experimentation 18 (suppl) 232-232, 2013.
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P-70 Application of coral particles for three-dimensional tissue culture on capillary
Tomoharu Okamura1, Tetsunari Nishikawa1, Masahiro Wato1, Kazuya Tominaga1, Hirohito Kato1, Koichi Imai2, Shoji Takeda2, Akio Tanaka1
1Department of Oral Pathology, Osaka Dental University, 2Department of Biomaterials, Osaka Dental University
Alternatives to Animal Testing and Experimentation 18 (suppl) 233-233, 2013.
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P-71 Hard tissue formation and change of extracelllar matrix by 3-D cultured HMS0014 cells using a collagen scaffold.
Shunji Kumabe, Michiko Nakatsuka, Katsura Ueda, Chunying An, Chizuko Inui-yamamoto, Yasutomo Iwai
Department of Oral Anatomy, Osaka Dental University
Alternatives to Animal Testing and Experimentation 18 (suppl) 234-234, 2013.
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P-72 Simulation of Dental Orthodontic Force on In Vitro Human Periodontal Ligament-like Tissue
Wen Liao1, Masahiro Okada2, Kaoru Inami3, Yoshiya Hashimoto2, Aki Nishiura3, Naoyuki Matsumoto3
1Graduate School of Dentistry, Department of Orthodontics, Osaka Dental University, 2Department of Biomaterials, Osaka Dental University, 3Department of Orthodontics, Osaka Dental University
Alternatives to Animal Testing and Experimentation 18 (suppl) 235-235, 2013.
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P-73 Inhibitory effects of mucolytic agent on type A seasonal influenza virus infection
Takenori Tamaki, Hideto Ariumi, Yuji Yoshiyama
Division of Community Pharmacy, Center for Clinical Pharmacy and Clinical Sciences, School of Pharmacy, Kitasato University
Alternatives to Animal Testing and Experimentation 18 (suppl) 236-236, 2013.
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P-74 KeraSkin(TM)-VM: A novel reconstructed human epidermis model for skin irritation tests
Kyoung-Mi Jung1, Su-Hyon Lee2, Won-Hee Jang1, Haeng-Sun Jung2, Young-Ho Park1, SeungHyeok Seok3, Kyung-Min Lim4
1Amorepacific Co. R&D Center, 2Modern Cell & Tissue Technologies Inc, 3Department of Microbiology and Immunology, and Institute of Endemic Disease, Seoul National University Medical College, 4College of Pharmacology, Ewha Womans University
Alternatives to Animal Testing and Experimentation 18 (suppl) 237-237, 2013.
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P-75 Bayesian Integrated Testing to assess the Skin Sensitization Potential of Chemicals
Petra Kern1, Yuri Dancik2, Cindy Ryan3, Leslie Foertsch3, Andreas Natsch4, Frank Gerberick3, Joanna Jaworska2
1Procter & Gamble Technology, Shunyi District, 2Procter & Gamble NV, 3Procter & Gamble Company, 4Givaudan Schweiz AG
Alternatives to Animal Testing and Experimentation 18 (suppl) 238-238, 2013.
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C2-2 Animal Welfare Legislation in Europe
Anderson,David.B, Louhimies,Susanna
European Commission
Alternatives to Animal Testing and Experimentation 18 (suppl) 240-240, 2013.
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C2-3 Animal Welfare and Practical Laboratory Animal Welfare
Tsutomu Miki Kurosawa
DVM, DVCS, DJCLAM, FBB
Alternatives to Animal Testing and Experimentation 18 (suppl) 241-241, 2013.
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