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Maintenance of Viability and Functional Expression of Cryopreserved Human Hepatocytes using Silicate Fiber-based Three-dimensional Scaffold
Takahiro Mizutami1, Takaaki Ishii1, Yuji Komizu1, Takuya Iwasa2, Masaaki Kawabe2, Naoyuki Togawa3, Seiichi Ishida4, Taku Matsushita1
1Division of Applied Life Science, Graduate School of Engineering, Sojo University, 2Central Research Laboratory, Japan Vilene Co.,Ltd., 3Yokohama Research Laboratories, Mitsubishi Rayon Co.,Ltd., 4Division of Pharmacology, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 22 (1) 101-106, 2017.
1Division of Applied Life Science, Graduate School of Engineering, Sojo University, 2Central Research Laboratory, Japan Vilene Co.,Ltd., 3Yokohama Research Laboratories, Mitsubishi Rayon Co.,Ltd., 4Division of Pharmacology, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 22 (1) 101-106, 2017.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
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A Study on an In Vitro Changeable pH Dissolution/permeation System That Reflects pH Shifts of the Gastrointestinal Tract : A Case of a Poorly Soluble Basic Drug
Ryotaro Miki, Yuuichi Hara, Nahomi Imai, Masahiro Sugino, Yuya Egawa, Osamu Hosoya, Kazuhiko Juni, Toshinobu Seki
Faculty of Pharmacy and Pharmaceutical Sciences, Josai University
Alternatives to Animal Testing and Experimentation 22 (1) 107-114, 2017.
Faculty of Pharmacy and Pharmaceutical Sciences, Josai University
Alternatives to Animal Testing and Experimentation 22 (1) 107-114, 2017.
- アブストラクト： 従量制は110円（税込）、基本料金制は基本料金に含まれます。
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
Evaluation report on the in vitro skin absorption tests
Kenji Sugibayashi1, Makiko Fujii2, Hiroaki Todo1
1Faculty of Pharmaceutical Sicneces, Josai University, 2Showa Pharmaceutical University
Alternatives to Animal Testing and Experimentation 22 (1) 126-126, 2017.
1Faculty of Pharmaceutical Sicneces, Josai University, 2Showa Pharmaceutical University
Alternatives to Animal Testing and Experimentation 22 (1) 126-126, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Evaluation report on the Fluorescein Leakage (FL) test for eye irritation testing
Isao Yoshimura1, Naoki Yamamoto2, Tadashi Kosaka3, Sanae Takeuchi4, Kazuhiro Hosoi5, Masakazu Katoh6, Momoko Sunouchi7, Mitsuteru Masuda7
1Tokyo University of Science, 2Laboratory of Molecularbiology, Institute of Joint Research, Fujita Health University, 3Study Management Division, The Institute of Environmental Toxicology, 4P&G Innovation Godo Kaisha, 5Santen Pharmaceutical Co.,Ltd., 6Japan Tissue Engineering Co.,Ltd., 7National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 22 (1) 127-127, 2017.
1Tokyo University of Science, 2Laboratory of Molecularbiology, Institute of Joint Research, Fujita Health University, 3Study Management Division, The Institute of Environmental Toxicology, 4P&G Innovation Godo Kaisha, 5Santen Pharmaceutical Co.,Ltd., 6Japan Tissue Engineering Co.,Ltd., 7National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 22 (1) 127-127, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Evaluation report on the in vitro PBMC (peripheral blood mononucleated cell) test method as an alternative to pyrogen testing
Ken-ichi Nakazawa1, Kazutoshi Shinoda2, Hajime Kojima1, Isao Yoshimura3, Goro Nishioka4, Ken J.Ishii5
1National Institute of Health Sciences, 2Center for Product Evalution, Pharmaceuticals and Medical Devices Agency, 3Tokyo University of Science, 4Fuso Pharmaceutical Industries, Ltd., 5Laboratory of Adjuvant Innovation, National Institute of Biomedical Innovation & Laboratory of Vaccine Science, Immunology Frontier Research Center
Alternatives to Animal Testing and Experimentation 22 (1) 128-128, 2017.
1National Institute of Health Sciences, 2Center for Product Evalution, Pharmaceuticals and Medical Devices Agency, 3Tokyo University of Science, 4Fuso Pharmaceutical Industries, Ltd., 5Laboratory of Adjuvant Innovation, National Institute of Biomedical Innovation & Laboratory of Vaccine Science, Immunology Frontier Research Center
Alternatives to Animal Testing and Experimentation 22 (1) 128-128, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Evaluation report on the BG1Luc estrogen receptor (ER) transactivation (TA) test method (BG1Luc ER TA)
Hiroshi Ono1, Tohru Marunouchi2, Taisen Iguchi3, Ken-ichi Nakazawa4
1Hatano Research Institute, Food and Drug Safety Center, 2Fujita Health University, 3National Institutes of Natural Sciences, National Institute for Basic Biology, Okazaki Institute for Integrative Bioscience, 4National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 22 (1) 129-129, 2017.
1Hatano Research Institute, Food and Drug Safety Center, 2Fujita Health University, 3National Institutes of Natural Sciences, National Institute for Basic Biology, Okazaki Institute for Integrative Bioscience, 4National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 22 (1) 129-129, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
JaCVAM annual report in 2013
Hajime Kojima1, Akiyoshi Nishikawa2
1Japanese Center for the Validation of Alternative Methods, National Center for Biological Safety and Research, National Institute of Health Sciences, 2National Center for Biological Safety and Research, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 22 (1) 130-130, 2017.
1Japanese Center for the Validation of Alternative Methods, National Center for Biological Safety and Research, National Institute of Health Sciences, 2National Center for Biological Safety and Research, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 22 (1) 130-130, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Evaluation report on the Revised OECD Test Guideline for Eye irritation/Corrosion (TG 405)
Tadashi Kosaka1, Momoko Sunouchi2, Sanae Takeuchi3, Mitsuteru Masuda, Masakazu Katoh4, Kazuhiro Hosoi5, Naoki Yamamoto6, Isao Yoshimura7
1The Institute of Environmental Toxicology, 2National Institute of Health Sciences, 3P&G Innovation Godo Kaisha, 4Japan Tissue Engineering Co.,Ltd., 5Santen Pharmaceutical Co.,Ltd., 6Fujita Health University, 7Tokyo University of Science
Alternatives to Animal Testing and Experimentation 22 (1) 131-131, 2017.
1The Institute of Environmental Toxicology, 2National Institute of Health Sciences, 3P&G Innovation Godo Kaisha, 4Japan Tissue Engineering Co.,Ltd., 5Santen Pharmaceutical Co.,Ltd., 6Fujita Health University, 7Tokyo University of Science
Alternatives to Animal Testing and Experimentation 22 (1) 131-131, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Evaluation report on the Bovine Corneal Opacity and Permeability Test (BCOP) for alter native to eye irritation test
Sanae Takeuchi1, Tadashi Kosaka2, Momoko Sunouchi3, Mitsuteru Masuda, Masakazu Katoh4, Kazuhiro Hosoi5, Naoki Yamamoto6, Isao Yoshimura7
1P&G Innovation Godo Kaisha, 2The Institute of Environmental Toxicology, 3National Institute of Health Sciences, 4Japan Tissue Engineering Co.,Ltd., 5Santen Pharmaceutical Co.,Ltd., 6Fujita Health University, 7Tokyo University of Science
Alternatives to Animal Testing and Experimentation 22 (1) 132-132, 2017.
1P&G Innovation Godo Kaisha, 2The Institute of Environmental Toxicology, 3National Institute of Health Sciences, 4Japan Tissue Engineering Co.,Ltd., 5Santen Pharmaceutical Co.,Ltd., 6Fujita Health University, 7Tokyo University of Science
Alternatives to Animal Testing and Experimentation 22 (1) 132-132, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Evaluation report on the Isolated Chicken Eye Test (ICR) for alternative to eye irritation test
Tadashi Kosaka1, Momoko Sunouchi2, Sanae Takeuchi3, Mitsuteru Masuda, Masakazu Katoh4, Kazuhiro Hosoi5, Naoki Yamamoto6, Isao Yoshimura7
1The Institute of Environmental Toxicology, 2National Institute of Health Sciences, 3P&G Innovation Godo Kaisha, 4Japan Tissue Engineering Co.,Ltd., 5Santen Pharmaceutical Co.,Ltd., 6Fujita Health University, Tokyo University of Science
Alternatives to Animal Testing and Experimentation 22 (1) 133-133, 2017.
1The Institute of Environmental Toxicology, 2National Institute of Health Sciences, 3P&G Innovation Godo Kaisha, 4Japan Tissue Engineering Co.,Ltd., 5Santen Pharmaceutical Co.,Ltd., 6Fujita Health University, Tokyo University of Science
Alternatives to Animal Testing and Experimentation 22 (1) 133-133, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Evaluation report on the Direct Peptide Reactivity Assay (DPRA) for alternative to skin sensitisation test
Naohiha Tsutsui1, Reiko Adachi2, Yukiko Kanazawa3, Koichi Kojima3, Kazuhiro Sato4, Masahiro Takeyoshi5, Takashi Morimoto6
1Mitsubishi Tanabe Pharma Corporation, 2National Institute of Health Sciences, 3Hatano Research Institute, Food and Drug Safety Center, 4University of Fukui Faculty of Medical Sciences, 5Chemicals Evaluation and Research Institute, 6Sumitomo Chemical Co.,Ltd.
Alternatives to Animal Testing and Experimentation 22 (1) 134-134, 2017.
1Mitsubishi Tanabe Pharma Corporation, 2National Institute of Health Sciences, 3Hatano Research Institute, Food and Drug Safety Center, 4University of Fukui Faculty of Medical Sciences, 5Chemicals Evaluation and Research Institute, 6Sumitomo Chemical Co.,Ltd.
Alternatives to Animal Testing and Experimentation 22 (1) 134-134, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Annual report on the Japanese Center for the Validation of Alternative Methods (JaCVAM) in 2014
Hajime Kojima, Akiyoshi Nishikawa
JaCVAM, Biological Safety Research Center, National Institute of Health Sciences (NIHS)
Alternatives to Animal Testing and Experimentation 22 (1) 135-135, 2017.
JaCVAM, Biological Safety Research Center, National Institute of Health Sciences (NIHS)
Alternatives to Animal Testing and Experimentation 22 (1) 135-135, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Evaluation Report on an Alternative Test Method for Skin Sensitization : ARE-Nrf2 Luciferase Test
Naohiha Tsutsui1, Reiko Adachi2, Yukiko Kanazawa3, Koichi Kojima3, Kazuhiro Sato4, Masahiro Takeyoshi5, Takashi Morimoto6
1Mitsubishi Tanabe Pharma Corporation, 2National Institute of Health Sciences, 3Hatano Research Institute, Food and Drug Safety Center, 4University of Fukui Faculty of Medical Sciences, 5Chemicals Evaluation and Research Institute, 6Sumitomo Chemical Co.,Ltd.
Alternatives to Animal Testing and Experimentation 22 (1) 136-137, 2017.
1Mitsubishi Tanabe Pharma Corporation, 2National Institute of Health Sciences, 3Hatano Research Institute, Food and Drug Safety Center, 4University of Fukui Faculty of Medical Sciences, 5Chemicals Evaluation and Research Institute, 6Sumitomo Chemical Co.,Ltd.
Alternatives to Animal Testing and Experimentation 22 (1) 136-137, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Evaluation Report on an Alternative Test Method for Ocular Irritation : Short Time Exposure In Vitro Test Method
Sanae Takeuchi1, Tadashi Kosaka2, Shoji Sasaki3, Satomi Morimura4, Isao Yoshimura5
1P&G Innovation Godo Kaisha, 2The Institute of Environmental Toxicology, 3Abbvie GK, 4Hatano Research Institute, Food and Drug Safety Center, 5Tokyo University of Science
Alternatives to Animal Testing and Experimentation 22 (1) 138-138, 2017.
1P&G Innovation Godo Kaisha, 2The Institute of Environmental Toxicology, 3Abbvie GK, 4Hatano Research Institute, Food and Drug Safety Center, 5Tokyo University of Science
Alternatives to Animal Testing and Experimentation 22 (1) 138-138, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Evaluation Report on an Alternative Test Method for Photosafety : Reactive Oxygen Species Assay
Ikuo Horii1, Satomi Onoue2, Kazuhiro Kaneko3, Hirokazu Kouzuki4, Noriho Tanaka5, Osamu Fueki6, Kazuhiro Hosoi7
1Pfizer Inc., 2University of Shizuoka, 3Japan Chemical Industry Association, 4Shiseido Global Innovation Center., 5Hatano Research Institute, Food and Drug Safety Center, 6Pharmaceuticals and Medical Devices Agency, 7Santen Pharmaceutical Co.,Ltd.
Alternatives to Animal Testing and Experimentation 22 (1) 139-139, 2017.
1Pfizer Inc., 2University of Shizuoka, 3Japan Chemical Industry Association, 4Shiseido Global Innovation Center., 5Hatano Research Institute, Food and Drug Safety Center, 6Pharmaceuticals and Medical Devices Agency, 7Santen Pharmaceutical Co.,Ltd.
Alternatives to Animal Testing and Experimentation 22 (1) 139-139, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
Annual report on the Japanese Center for the Validation of Alternative Methods (JaCVAM) in 2015
Hajime Kojima, Akiyoshi Nishikawa
JaCVAM, Biological Safety Research Center, National Institute of Health Sciences (NIHS)
Alternatives to Animal Testing and Experimentation 22 (1) 140-140, 2017.
JaCVAM, Biological Safety Research Center, National Institute of Health Sciences (NIHS)
Alternatives to Animal Testing and Experimentation 22 (1) 140-140, 2017.
- 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
