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P.13 掲載の参考文献

• 1) Piek JM, van Diest PJ, Zweemer RP, et al : Tubal ligation and risk of ovarian cancer. Lancet 2001, 358 : 844
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• 2) Longrace TA, Wells M : Serous tumours. In : WHO Classification of Tumours of Female Reproductive Organs. (Kurman RJ, Carcangiu ML, Herrington CS. et al. eds.) IARC, Lyon, 2014, 15-16

• 3) 三上芳喜 : 漿液性腫瘍. 腫瘍病理鑑別診断アトラス. (本山悌一, 坂本穆彦編) 文光堂, 東京, 2012, 12-32

• 4) Seidman JD, Cho KR, Ronnett BM, et al : Surface epithelial tumors of the ovary. In : Blaustein's Pathology of the Female Genital Tract. (Kurman RJ, Ellenson LH, Ronnett BM, eds.), 6th edition. Springer Verlag, New York, 2011, 680-784

• 5) Teilum G : Special tumors of ovary and testis. Munksgaad, Copenhagen, 1971

• 6) Nogales FF, Preda O, Nicolae A : Yolk sac tumors revisited. A review of their many faces and names. Histopathology 2012, 60 : 1023-1033

• 7) 中島久良, 塩田充, 西田敬 : 良性の卵巣腫瘍. 新女性医学大系 39 : 産婦人科の良性腫瘍. 中山書店, 東京, 1999, 90-139

• 8) 日本産科婦人科学会婦人科腫瘍委員会第55回治療年報 : 日本産婦人科学会雑誌, 2015, 67 : 1189-1257

• 9) Goldgar D, Strawtton MR, Eeles R, et al : Inherited tumour syndrome. In : WHO Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs. (Tavassoli FA, Devilee P, eds.) IARC, Lyon, 2003, 335-363

P.15 掲載の参考文献

• 1) Heatley MK : A systematic review of papers examining the use of intraoperative frozen section in predicting the final diagnosis of ovarian lesions. Int J Gynecol Pathol 2012, 31 : 111-115

• 2) Nochomovitz L, Sidawy M, Silverberg S, et al : Intraoperative Consultation : A Guide to Smears, Imprints, & Frozen Sections. ASCP Press, 1989, 24-41

• 3) Kigawa J, Kaku T, Sugiyama T, et al : Atlas of Clear Cell Carcinoma of the Ovary. A Pathological Guide. Springer Japan, Tokyo, 2015

P.20 掲載の参考文献

• 1) Shih IeM, Kurman RJ : Ovarian tumorigenesis : a proposal model based on morphological and molecular genetic analysis. Am J Pathol 2004, 164 : 1511-1518

• 2) Kurman RJ, Shih IeM : Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer : shifting the paradigm. Hum Pathol 2011, 42 : 918-931

• 3) Clapier CR, Cairns BR : The biology of chromatin remodeling complexes. Annu Rev Biochem 2009, 78 : 273-304

• 4) Oike T, Ogiwara H, Nakano T, et al : Inactivating mutations in SWI/SNF chromatin remodeling genes in human cancer. Jpn J Clin Oncol 2013, 43 : 849-855

• 5) Wiegand KC, Shah SP, Al-Agha OM, et al : ARID1A mutations in endometriosis-associated ovarian carcinomas. N Engl J Med 2010, 363 : 1532-1543

• 6) Katagiri A, Nakayama K, Rahman MT, et al : Loss of ARID1A expression is related to shorter progression-free survival and chemoresistance in ovarian clear cell carcinoma. Mod Pathol 2012, 25 : 282-288

• 7) Yamamoto S, Tsuda H, Takano M, et al : PIK3CA mutations and loss of ARID1A protein expression are early events in the development of cystic ovarian clear cell adenocarcinoma. Virchows Arch 2012, 460 : 77-87

• 8) Takenaka M, Saito M, Iwakawa R, et al : Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing. Int J Oncol 2015, 46 : 2389-2398

• 9) Tan DS, Miller RE, Kaye SB : New perspectives on molecular targeted therapy in ovarian clear cell carcinoma. Br J Cancer 2013, 30 : 1553-1559

• 10) Saito M, Okamoto A, Takakura S, et al : Allelic imbalance and mutations of the PTEN gene in ovarian cancer. Int J Cancer 2000, 85 : 160-165

• 11) Gurung A, Hung T, Morin J, et al : Molecular abnormalities in ovarian carcinoma : clinical, morphological and therapeutic correlates. Histopathology 2013, 62 : 59-70

• 12) Enomoto T, Weghorst CM, Inoue M, et al : K-ras activation occurs frequently in mucinous adenocarcinomas and rarely in other common epithelial tumors of the human ovary. Am J Pathol 1991, 139 : 777-785

• 13) Mok SC, Bell DA, Knapp RC, et al : Mutation of K-ras protooncogene in human ovarian epithelial tumors of borderline malignancy. Cancer Res 1993, 53 : 1489-1492

• 14) Ratner ES, Keane FK, Linder R, et al : A KRAS variant is a biomarker of poor outcome, platinum chemotherapy resistance and a potential target for therapy in ovarian cancer. Oncogene 2012, 31 : 4559-4566

• 15) Davies H, Bignell GR, Cox C, et al : Mutations of the BRAF gene in human cancer. Nature 2002, 417 : 949-954

• 16) Matsumoto T, Yamazaki M, Takahashi H, et al : Distinct β-catenin and PIK3CA mutation profiles in endometriosis-associated ovarian endometrioid and clear cell carcinomas. Am J Clin Pathol 2015, 144 : 452-463

• 17) McAlpine JN, Wiegand KC, Vang R, et al : HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy. BMC Cancer 2009, 9 : 433

• 18) Bewtra C, Watson P, Conway T, et al : Hereditary ovarian cancer : a clinicopathological study. Int J Gynecol Pathol 1992, 11 : 180-187

• 19) Ketabi Z, Bartuma K, Bernstein I, et al : Ovarian cancer linked to Lynch syndrome typically presents as early-onset, non-serous epithelial tumors. Gynecol Oncol 2011, 121 : 462-465

• 20) Niskakoski A, Kaur S, Renkonen-Sinisalo, et al : Distinct molecular profiles in Lynch syndrome-associated and sporadic ovarian carcinomas. Int J Cancer 2013, 133 : 2596-2608

• 21) DeLeo AB, Jay G, Appella E, et al : Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse. Proc Natl Acad Sci U S A 1979, 76 : 2420-2424

• 22) Okamoto A, Sameshima Y, Yokoyama S, et al : Frequent allelic losses and mutations of the p53 gene in human ovarian cancer. Cancer Res 1991, 51 : 5171-5176

• 23) Cancer Genome Atlas Research Network : Integrated genomic analyses of ovarian carcinoma. Nature 2011, 474 : 609-615

• 24) Patch AM, Christie EL, Etemadmoghadam D, et al : Whole-genome characterization of chemoresistant ovarian cancer. Nature 2015, 521 : 489-494

• 25) Mavaddat N, Peock S, Frost D, et al : Cancer risks for BRCA1 and BRCA2 mutation carriers : results from prospective analysis of EMBRACE. J Natl Cancer Inst 2013, 105 : 812-822

• 26) Chen S, Iversen ES, Friebel T, et al : Characterization of BRCA1 and BRCA2 mutations in a large United States sample. J Clin Oncol 2006, 24 : 863-871

• 27) Bowtell DD : The genesis and evolution of high-grade serous ovarian cancer. Nat Rev Cancer 2010, 10 : 803-808

P.30 掲載の参考文献

• 1) Outwater EK, Dunton CJ : Imaging of the ovary and adnexa : clinical issues and applications of MR imaging. Radiology 1995, 194 : 1-18

• 2) Siegelman ES, Outwater EK : Tissue characterization in the female pelvis by means of MR imaging. Radiology 1999, 212 : 5-18

• 3) Jung SE, Lee JM, Rha SE, et al : CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics 2002, 22 : 1305-1325

• 4) Vargas HA, Barrett T, Sala E : MRI of ovarian masses. J Magn Reson Imaging 2013, 37 : 265-281

• 5) Lai CH, Lin G, Yen TC, et al : Molecular imaging in the management of gynecologic malignancies. Gynecol Oncol 2014, 135 : 156-162

• 6) 田中優美子 : 産婦人科の画像診断. 金原出版, 東京, 2014

P.36 掲載の参考文献

• 1) 日本婦人科腫瘍学会編 : 卵巣がん治療ガイドライン2015年版 (第4版), 金原出版, 東京, 2015

• 2) Vergote I, Trope CG, Amant F, et al : Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer. N Engl J Med 2010, 363 : 943-953

• 3) Katsumata N, Yasuda M, Takahashi F, et al : Dose-dense paclitaxel once a week in combination with carboplatin every 3 weeks for advanced ovarian cancer : a phase 3, open-label, randomised controlled trial. Lancet 2009, 374 : 1331-1338

• 4) Katsumata N, Yasuda M, Isonishi S, et al : Long-term results of dose-dense paclitaxel and carboplatin versus conventional paclitaxel and carboplatin for treatment of advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer (JGOG 3016) : a randomised, controlled, open-label trial. Lancet Oncol 2013, 14 : 1020-1026
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• 5) Armstrong DK, Bundy B, Wenzel L, et al : Intraperitoneal cisplatin and paclitaxel in ovarian cancer. N Eng J Med 2006, 354 : 34-43

• 6) Elit L, Oliver TK, Covens A, et al : Intraperitoneal chemotherapy in the first-line treatment of women with stage III epithelial ovarian cancer : a systematic review with metaanalyses. Cancer 2007, 109 : 692-702

• 7) Okamoto A, Sugiyama T, Hamano T, et al : Randomized phase III trial of paclitaxel/carboplatin (PC) versus cisplatin/ irinotecan (CPT-P) as first-line chemotherapy in patients with clear cell carcinoma (CCC) of the ovary : a Japanese Gynecologic Oncology Group (JGOG) /GCIG study. J Clin Oncol 2014, 32 : 5 s (Suppl ; abstr 5507)

• 8) Burger RA, Brady MF, Bookman MA, et al : Incorporation of bevacizumab in the primary treatment of ovarian cancer. N Engl J Med 2011, 365 : 2473-2483

• 9) Perren TJ, Swart AM, Pfisterer J, et al : A phase 3 trial of bevacizumab in ovarian cancer. N Engl J Med 2011, 365 : 2484-2496

• 10) Aghajanian C, Blank SV, Goff BA, et al : OCEANS : a randomized, double-blind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer. J Clin Oncol 2012, 30 : 2039-2045

• 11) Pujade-Lauraine E, Hilpert F, Weber B, et al : Bevacizumab combined with chemotherapy for platinum-resistant recurrent ovarian cancer : The AURELIA open-label randomized phase III trial. J Clin Oncol 2014, 32 : 1302-1308

• 12) 卵巣腫瘍・卵管癌・腹膜癌取扱い規約 臨床編 (第1版). 金原出版, 東京, 2015

• 13) Ovarian Cancer including Fallopian Tube Cancer and Primary Peritoneal Cancer (Version 2. 2013). NCCN Clinical Practice Guidelines in Oncology

• 14) Gershenson DM : Management of ovarian germ cell tumors. J Clin Oncol 2007, 25 : 2938-2943

• 15) NCI Ovarian Germ Cell Tumors treatment (PDQ(R)) Health Professional Version (09/10/2012))

• 16) Colombo N, Parma G, Zanagnolo V, et al : Management of ovarian stromal cell tumors. J Clin Oncol 2007, 25 : 2944-2951

• 17) Cancer Genome Atlas Research Network : Integrated genomic analyses of ovarian carcinoma. Nature 2011, 474 : 609-615

• 18) Murakami R, Matsumura N, Mandai M, et al : Establishment of a novel histopathological classification of high-grade serous ovarian carcinoma correlated with prognostically distinct gene expression subtypes. Am J Pathol 2016, 186 : 1103-1113

• 19) Gourley C, McCavigan A, Perren T, et al : Molecular subgroup of high-grade serous ovarian cancer (HGSOC) as a predictor of outcome following bevacizumab. J Clin Oncol 2014, 32 : 5s (Suppl ; abstr 5502)

• 20) Winterhoff BJN, Kommoss S, Oberg AL, et al : Bevacizumab and improvement of progression-free survival (PFS) for patients with the mesenchymal molecular subtype of ovarian cancer. J Clin Oncol 2014, 32 : 5s (Suppl ; abstr 5509)

P.41 掲載の参考文献

• 1) Miki Y, Swensen J, Shattuck-Eidens D, et al : A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994, 266 : 66-71

• 2) Wooster R, Bignell G, Lancaster J, et al : Identification of the breast cancer susceptibility gene BRCA2. Nature 1995, 378 : 789-792

• 3) 日本婦人科腫瘍学会編 : 卵巣がん治療ガイドライン2015年版. 金原出版, 東京, 2015

• 4) Buys SS, Partridge E, Black A, et al : Effect of screening on ovarian cancer mortality. The Prostate, Lung, Colorectal and Ovarian (PLCO) cancer screening randomized controlled trial. JAMA 2011, 305 : 2295-2303

• 5) Rosenthal AN, Fraser L, Manchanda R, et al : Results of annual screening in phase I of the United Kingdom familial ovarian cancer screening study highlight the need for strict adherence to screening schedule. J Clin Oncol 2013, 31 : 49-57

• 6) Kauff ND, Domchek SM, Friebel TM, et al : Risk-reducing salpingo-oophorectomy for the prevention of BRCA1- and BRCA2-associated breast and gynecologic cancer : a multicenter, prospective study. J Clin Oncol 2008, 26 : 1331-1337

• 7) Domchek SM, Friebel TM, Singer CF, et al : Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality. JAMA 2010, 304 : 967-975

• 8) Pal T, Permuth-Wey J, Betts JA, et al : BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases. Cancer 2005, 104 : 2807-2816

• 9) Tan DS, Rothermundt C, Thomas K, et al : "BRCAness" syndrome in ovarian cancer : a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations. J Clin Oncol 2008, 26 : 5530-5536

• 10) Ledermann J, Harter P, Gourley C, et al : Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer : a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial. Lancet Oncol 2014, 15 : 852-861

• 11) Okamura H, Katabuchi H, Ohba T : What we have learned from isolated cells from human ovary? Mol Cell Endocrinol 2003, 202 : 37-45

• 12) Medeiros F, Muto MG, Lee Y, et al : The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome. Am J Surg Pathol 2006, 30 : 230-236

P.49 掲載の参考文献

• 1) 日本臨床細胞学会編 :細胞診ガイドライン 1 婦人科・泌尿器2015年版 : 外陰/腟/子宮頸部/子宮体部/卵巣/泌尿器. 金原出版, 東京, 2015, 109-166

• 2) Kurman RJ, Carcangiu LC, Herrington CS, et al. eds : WHO Classification of Tumours of Female Reproductive Organs. 4th edition. IARC, Lyon, 2014

• 3) 日本産科婦人科学会・日本病理学会編 : 卵巣腫瘍・卵管癌・腹膜癌取扱い規約 臨床編. 金原出版, 東京, 2015

• 4) Kigawa J, Kaku T, Sugiyama T, et al : Atlas of Clear Cell Carcinoma of the Ovary : A Pathological Guide. Springer, Heidelberg, 2015

P.52 掲載の参考文献

• 1) Piek JM, van Diest PJ, Zweemer RP, et al : Dysplastic changes in prophylactically removed Fallopian tubes of women predisposed to developing ovarian cancer. J Pathol 2001, 195 : 451-456

• 2) Colgan TJ, Murphy J, Cole DE, et al : Occult carcinoma in prophylactic oophorectomy specimens : prevalence and association with BRCA germline mutation status. Am J Surg Pathol 2001, 25 : 1283-1289

• 3) Medeiros F, Muto MG, Lee Y, et al : The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome. Am J Surg Pathol 2006, 30 : 230-236

• 4) Kindelberger DW, Lee Y, Miron A, et al : Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma : evidence for a causal relationship. Am J Surg Pathol 2007, 31 : 161-169

• 5) Gilks CB, Irving J, Kobel M, et al : Incidental nonuterine high-grade serous carcinomas arise in the fallopian tube in most cases : further evidence for the tubal origin of high-grade serous carcinomas. Am J Surg Pathol 2015, 39 : 357-364

• 6) Prat J : Staging classification for cancer of the ovary, fallopian tube, and peritoneum : abridged republication of guidelines from the international federation of gynecology and obstetrics (FIGO). Obstet Gynecol 2015, 126 : 171-174

• 7) Singh N, Gilks CB, Wilkinson N, et al : Assignment of primary site in high-grade serous tubal, ovarian and peritoneal carcinoma : a proposal. Histopathology 2014, 65 : 149-154

P.57 掲載の参考文献

• 1) Wenzl R, Lehner R, Husslein P, et al : Laparoscopic surgery in cases of ovarian malignancies : an Austrian-wide survey. Gynecol Oncol 1996, 63 : 57-61

• 2) Piek JM, van Diest PJ, Zweemer RP, et al : Tubal ligation and risk of ovarian cancer. Lancet 2001, 358 : 844
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• 5) Seidman JD, Kurman RJ, Ronnett BM : Primary and metastatic mucinous adenocarcinomas in the ovaries : incidence in routine practice with a new approach to improve intraoperative diagnosis. Am J Surg Pathol 2003, 27 : 985-993

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P.62 掲載の参考文献

• 1) Prat J, FIGO Committee on Gynecologic Oncology : Staging classification for cancer of the ovary, fallopian tube, and peritoneum. Int J Gynaecol Obstet 2014, 124 : 1-5

• 2) 日本産科婦人科学会, 日本病理学会編 : 卵巣腫瘍・卵管癌・腹膜癌取扱い規約 臨床編 (第1版). 金原出版, 東京, 2015

• 3) Leslie HS, Christian W編 : TNM 悪性腫瘍の分類 (第7版 日本語版). (UICC日本委員会TNM 委員会訳). 金原出版, 東京, 2010

• 4) UICC : TNM Classification of Malignant Tumours 7th edition. 7th edition TNM and Ovary, Fallopian tube and primary peritoneal carcinoma FIGO 2014. <http://www.uicc.org/sites/main/files/atoms/files/TNM_7_FIGO_OVARY_2014%20FINAL_0.pdf> [Cited 25 Jan 2015]

P.67 掲載の参考文献

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P.74 掲載の参考文献

• 1) Dabbs DJ : Immunohistology of the female genital tract. In : Diagnostic Immunohistochemistry, 3rd edition. Saunders, Philadelphia, 2010, 721-742

• 2) Kaspar HG, Crum CP : The utility of immunohistochemistry in the differential diagnosis of gynecologic disorders. Arch Pathol Lab Med 2015, 139 : 39-54

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P.80 掲載の参考文献

• 1) Nogales FF, Bergeron C, Carvia RE, et al : Ovarian endometrioid tumors with yolk sac tumor component, an unusual form of ovarian neoplasm. Analysis of six cases. Am J Surg Pathol 1996, 20 : 1056-1066

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• 3) Roma AA, Przybycin CG : Yolk sac tumor in postmenopausal patients : pure or associated with adenocarcinoma, a rare phenomenon. Int J Gynecol Pathol 2014, 33 : 477-482
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P.85 掲載の参考文献

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P.91 掲載の参考文献

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P.96 掲載の参考文献

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P.102 掲載の参考文献

• 1) Kurman RJ, Carcangiu ML, Herrington CS, et al, eds. : WHO Classification of Tumours of Female Reproductive Organs, 4 th edition. IARC, Lyon, 2014, 15-24

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P.109 掲載の参考文献

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