書籍詳細

I FD の実態に迫る

P.5 掲載の参考文献

• 1) Colin-Jones D, Bloom B, Bodemar G et al : Management of dyspepsia : report of a working party. Lancet 331 : 576-579, 1988.

• 2) Tack J, Talley NJ, Camilleri M et al : Functional gastroduodenal disorders. Gastroenterology 130 : 1466-1479, 2006.
  pubmed

• 3) 日本消化器病学会編 : 機能性消化管疾患診療ガイドライン 2014-機能性ディスペプシア (FD). 南江堂, 東京, 2014.

• 4) Kaji M, Fujiwara Y, Shiba M et al : Prevalence of overlaps between GERD, FD and IBS and impact on health-related quality of life. J Gastroenterol Hepatol 25 : 1151-1156, 2010.
  pubmed

• 5) Brook RA, Kleinman NL, Choung RS et al : Functional dyspepsia impacts absenteeism and direct and indirect costs. Clin Gastroenterol Hepatol 8 : 498-503, 2010.
  pubmed

• 6) Miwa H : Life style in persons with functional gastrointestinal disorders--large-scale internet survey of lifestyle in Japan. Neurogastroenterol Motil 24 : 464-471, e217, 2012.
  pubmed

• 7) Aro P, Talley NJ, Ronkainen J et al : Anxiety is associated with uninvestigated and functional dyspepsia (Rome III criteria) in a Swedish population-based study. Gastroenterology 137 : 94-100, 2009.

P.10 掲載の参考文献

• 1) Tahara T, Arisawa T, Shibata T et al : Association of endoscopic appearances with dyspeptic symptoms. J Gastroenterol 43 : 208-215, 2008.
  pubmed

• 2) Arisawa T, Tahara T, Shiroeda H et al : Genetic polymorphisms of SCN10A are associated with functional dyspepsia in Japanese subjects. J Gastroenterol 48 : 73-80, 2013.
  pubmed

• 3) 有沢富康 : 機能性ディスペプシアとHelicobacter pylori関連ディスペプシア. 日消誌 111 : 1088-1095, 2014.
  Medical*Online

P.18 掲載の参考文献

• 1) Tack J, Talley NJ, Camilleri M et al : Functional gastroduodenal disorders. Gastroenterology 130 : 1466-1479, 2006.
  pubmed

• 2) Oshima T, Okugawa T, Tomita T et al : Generation of dyspeptic symptoms by direct acid and water infusion into the stomachs of functional dyspepsia patients and healthy subjects. Aliment Pharmacol Ther 35 : 175-182, 2012.
  pubmed

• 3) Oshima T, Nakajima S, Yokoyama T et al : The G-protein beta3 subunit 825 TT genotype is associated with epigastric pain syndrome-like dyspepsia. BMC Med Genet 11 : 13, 2010.

• 4) Lawal A, Barboi A, Krasnow A et al : Rapid gastric emptying is more common than gastroparesis in patients with autonomic dysfunction. Am J Gastroenterol 102 : 618-623, 2007.
  pubmed

• 5) Miwa H, Nakajima K, Yamaguchi K et al : Generation of dyspeptic symptoms by direct acid infusion into the stomach of healthy Japanese subjects. Aliment Pharmacol Ther 26 : 257-264, 2007.
  pubmed

• 6) Farre R, Vanheel H, Vanuytsel T et al : In functional dyspepsia, hypersensitivity to postprandial distention correlates with meal-related symptom severity. Gastroenterology 145 : 566-573, 2013.
  pubmed

• 7) Toyoshima F, Oshima T, Nakajima S et al : Serotonin transporter gene polymorphism may be associated with functional dyspepsia in a Japanese population. BMC Med Genet 12 : 88, 2011.

• 8) Oshima T, Miwa H : Treatment of functional dyspepsia : where to go and what to do. J Gastroenterol 41 : 718-719, 2006.

• 9) Futagami S, Shindo T, Kawagoe T et al : Migration of eosinophils and CCR2-/CD68-double positive cells into the duodenal mucosa of patients with postinfectious functional dyspepsia. Am J Gastroenterol 105 : 1835-1842, 2010.
  pubmed

• 10) Haug TT, Svebak S, Wilhelmsen I et al : Psychological factors and somatic symptoms in functional dyspepsia. A comparison with duodenal ulcer and healthy controls. J Psychosom Res 38 : 281-29. 1, 1994.

P.25 掲載の参考文献

• 1) 日本消化器病学会 : 機能性消化管疾患 診療ガイドライン 2014-機能性ディスペプシア (FD), 南江堂, 東京, 2014.

• 2) Manabe N, Haruma K, Hata J et al : Clinical characteristics of Japanese dyspeptic patients : is the Rome III classification applicable? Scand J Gastroenterol 45 : 567-572, 2010.
  pubmed

• 3) Stanghellini V : Three-month prevalence rates of gastrointedtinal symptoms and the influence of demographic factors : results from the Domestic/International Gastroenterology Surveillance Study (DIGEST). Scand J Gastroenterol 34 (Suppl 231) : S20-S28, 1999.

• 4) 眞部紀明, 楠裕明, 春間賢 : FDは長期的にどのような経過をたどるでしょうか? FD診療 Q&A, 日本医事新報社, 東京, 2011, pp. 151-156.

• 5) Kaji M, Fujiwara Y, Shiba M et al : Prevalence of overlaps between GERD, FD and IBS and impact on health-related quality of life. J Gastroenterol Hepatol 25 : 1151-1156, 2010.
  pubmed

II FD のガイドラインと診断の進め方

P.31 掲載の参考文献

• 1) 日本消化器病学会編 : 機能性消化管疾患診療ガイドライン 2014-機能性ディスペプシア (FD). 南江堂, 東京, 2014.

• 2) Kusano M, Hosaka H, Kuribayashi S et al : Development and evaluation of a modified FSSG (Frequency Scale for the Symptoms of Gastroesophageal reflux disease) to distinguish functional dyspepsia from non-erosive reflux disease. J Gastroenterol Hepatol 27 : 1187-1191, 2012.

• 3) 本郷道夫, 福土審, 庄司知隆ほか : 機能性胃腸症の病態と治療. 日本内科学会雑誌 101 : 2690-2697, 2012.

• 4) Hammer J, Eslick GD, Howell SC et al : Diagnostic yield of alarm features in irritable bowel syndrome and functional dyspepsia. Gut 53 : 666-672, 2004,
  pubmed

• 5) Straus WL, Ofman JJ, MacLean C et al : Do NSAIDs cause dyspepsia? a meta-analysis evaluating alternative dyspepsia definitions. Am J gastroenterol 97 : 1951-1958, 2002.
  pubmed

• 6) Kato M, Terao S, Adachi K et al : Changes in endoscopic findings of gastritis after cure of H. pylori infection : multicenter prospective trial. Dig Endosc 25 : 264-273, 2013.
  pubmed

• 7) Sugano K : Should we still subcategorize helicobacter pylori-associated dyspepsia as functional disease? J Neurogastroenterol Motil 17 : 366-371, 2011.

P.38 掲載の参考文献

• 1) 日本消化器病学会編 : 機能性消化管疾患診療ガイドライン 2014-機能性ディスペプシア (FD). 南江堂. 東京, 2014.

• 2) 河村朗, 野中洋, 八坂成暁ほか : 「むねやけ」についての検討. 消化器の臨床 6 : 231-234, 2003.

• 3) Adachi K, Matsumori Y, Fujisawa T et al : Symptom diversity of patients with reflux esophagitis : effect of omeprazole treatment. J Clin Biochem Nutr 39 : 46-54, 2006.

• 4) Kinoshita Y, Chiba T ; FUTURE Study Group : Characteristics of Japanese patients with chronic gastritis and comparison with functional dyspepsia defined by ROME III criteria : based on the large-scale survey : FUTURE study. Intern Med 50 : 2269-2276, 2011.

• 5) Talley NJ, Locke GR, Lahr BD et al : Predictors of the placebo response in functional dyspepsia. Aliment Pharmacol Ther 23 : 923-936, 2006.
  pubmed

• 6) Ashizawa N, Hashimoto T, Miyake T et al : Efficacy of camostat mesilate compared with famotidine for treatment of functional dyspepsia : is camostat mesilate effective? J Gastroenterol Hepatol 21 : 767-771, 2006.
  pubmed

• 7) Kakuta E, Yamashita N, Katsube T et al : Abdominal symptom-related QOL in individuals visiting an out-patient clinic and those attending an annual health check. Intern Med 50 : 1517-1522, 2011.

• 8) Kusano M, Shimoyama Y, Sugimoto S et al : Development and evaluation of FSSG : frequency scale for the symptoms of GERD. J Gastroenterol 39 : 888-891, 2004.
  pubmed

P.47 掲載の参考文献

• 1) 日本消化器病学会編 : 機能性消化管疾患診療ガイドライン 2014-機能性ディスペプシア (FD), 南江堂, 東京, 2014.

• 2) 本郷道夫, 相模泰宏 : 慢性胃炎の治療とdyspepsia. Progress in Medicine 19 : 2024-2027, 1999.

• 3) Veldhuyzen van Zanten SJ, Cleary C, Talley NJ et al : Drug treatment of functional dyspepsia : a systematic analysis of trial methodology with recommendations for design of future trials, Am J Gastroenterol 91 : 660-673, 1996.
  pubmed

• 4) Mearin F, Balboa A, Zarate N et al : Placebo in functional dyspepsia : symptomatic, gastrointestinal motor, and gastric sensorial responses. Am J Gastroenterol 94 : 116-125, 1999.
  pubmed

• 5) Hongo M, Harasawa S, Mine T et al : Large-scale randomized clinical study on functional dyspepsia treatment with mosapride or teprenone : Japan Mosapride Mega-Study (JMMS). J Gastroenterol Hepatol 27 : 62-68, 2012.
  pubmed

• 6) Delaney BC, Moayyedi P, Forman D : Initial management strategies for dyspepsia. Cochrane Database Syst Rev (2) : CD001961, 2003.
  pubmed

• 7) Miwa H, Ghoshal UC, Fock KM et al : Asian consensus report on functional dyspepsia. J Gastroenterol Hepatol 27 : 626-641, 2012.
  pubmed

• 8) American Gastroenterological Association : American Gastroenterological Association Technical Review on the Evaluation of Dyspepsia. Gastroenterology 129 : 1756-1780, 2005.

• 9) Talley NJ, Vakil N, Practice Parameters Committee of the American College of Gastroenterology : Guidelines for the management of dyspepsia. Am J Gastroenterol 100 : 2324-2337, 2005.
  pubmed

• 10) Veldhuyzen van Zanten SJ, Bradette M, Chiba N et al : Evidence-based recommendations for short- and long-term management of uninvestigated dyspepsia in primary care : An update of the Canadian Dyspepsia Working Group (CanDys) clinical management tool. Can J Gastroenterol 19 : 285-303, 2005.

• 11) National Institute for Health and Care Excellence : Dyspepsia : Managing dyspepsia in adults in primary care. http://www.nice.org.uk/pdf/CG-017fullguideline.pdf,2004.

• 12) Scottish Intercollegiate Guidelines Network : Dyspepsia : A national clinical guideline. http://www.sign.ac.uk/pdf/sign68.pdf,2003.

III FD のガイドラインと治療の実際

P.56 掲載の参考文献

• 1) 日本消化器病学会編 : 機能性消化管疾患診療ガイドライン 2014-機能性ディスペプシア (FD). 南江堂, 東京, 2014.

• 2) Hongo M, Harasawa S, Mine T et al : Large-scale randomized clinical study on functional dyspepsia treatment with mosapride or teprenone : Japan Mosapride Mega-Study (JMMS). J Gastroenterol Hepatol 27 : 62-68, 2012.
  pubmed

• 3) Sakurai K, Nagahara A, Inoue K et al : Efficacy of omeprazole, famotidine, mosapride and teprenone in patients with upper gastrointestinal symptoms : an omeprazole-controlled randomized study (J-FOCUS). BMC Gastroenterol 12 : 42, 2012.

• 4) Moayyedi P, Soo S, Deeks J et al : Pharmacological interventions for non-ulcer dyspepsia. Cochrane Database Syst Rev 4 : CD001960, 2006.
  pubmed

• 5) Miwa H, Nakajima K, Yamaguchi K et al : Generation of dyspeptic symptoms by direct acid infusion into the stomach of healthy Japanese subjects. Aliment Pharmacol Ther 26 : 257-264, 2007.
  pubmed

• 6) Collen MJ, Loebenberg MJ : Basal gastric acid secretion in nonulcer dyspepsia with or without duodenitis. Dig Dis Sci 34 : 246-250, 1989.

• 7) Nyren O : Secretory abnormalities in functional dyspepsia. Scand J Gastroenterol 182 (Suppl) : 25-28, 1991.

• 8) Oshima T, Okugawa T, Tomita T et al : Generation of dyspeptic symptoms by direct acid and water infusion into the stomachs of functional dyspepsia patients and healthy subjects. Aliment Pharmacol Ther 35 : 175-182, 2012.
  pubmed

• 9) Mizuta Y, Shikuwa S, Isomoto H et al : Recent insights into digestive motility in functional dyspepsia. J Gastroenterol 41 : 1025-1040, 2006.
  pubmed

• 10) Tack J, Piessevaux H, Coulie B et al : Role of impaired gastric accommodation to a meahn functional dyspepsia. Gastroenterology 115 : 1346-1352, 1998.
  pubmed

• 11) Ochi M, Tominaga K, Tanaka F et al : Clinical classification of subgroups according to the Rome III criteria cannot be used to distinguish the associated respective pathophysiology in Japanese patients with functional dyspepsia. Intern Med 52 : 1289-1293, 2013.

• 12) Xiao YL, Peng S, Tao J et al : Prevalence and symptom pattern of pathologic esophageal acid reflux in patients with functional dyspepsia based on the Rome III criteria. Am J Gastroenterol 105 : 2626-2631, 2010.
  pubmed

• 13) Talley NJ, Meineche-Schmidt V, Pare P et al : Efficacy of omeprazole in functional dyspepsia : double-blind, randomized, placebo-controlled trials (the Bond and Opera studies). Aliment Pharmacol Ther 12 : 1055-1065, 1998.
  pubmed

• 14) Wang WH, Huang JQ, Zheng GF et al : Effects of proton-pump inhibitors on functional dyspepsia : a meta-analysis of randomized placebo-controlled trials. Clin Gastroenterol Hepatol 5 : 178-185, 2007.
  pubmed

• 15) Perri F, Clemente R, Festa V et al : Patterns of symptoms in functional dyspepsia : role of Helicobacter pylori infection and delayed gastric emptying. Am J Gastroenterol 93 : 2082-2088, 1998.
  pubmed

• 16) Lan L, Yu J, Chen YL et al : Symptom-based tendencies of Helicobacter pylori eradication in patients with functional dyspepsia. World J Gastroenterol 17 : 3242-3247, 2011.

• 17) Miwa H, Hirai S, Nagahara A et al : Cure of Helicobacter pylori infection does not improve symptoms in non-ulcer dyspepsia patients-a double-blind placebo-controlled study. Aliment Pharmacol Ther 14 : 317-324, 2000.

P.64 掲載の参考文献

• 1) Feinle-Bisset C, Meier B, Fried M et al : Role of congnitive factors in symptom induction following high and low fat meats in patients with functional dyspepsia. Gut 52 (10) : 1414-1418, 2003.

• 2) Pilichiewicz AN, Horowitz M, Holtmann GJ et al : Relationship between symptoms and dietary patterns in patients with functional dyspepsia. Clin Gastroenterol Hepatol 7 (3) : 317-322, 2009.
  pubmed

• 3) 中田浩二, 小曽根基裕, 羽生信義ほか : FDと食生活習慣の関係とその指導. 消化器の臨床 11 (4) : 434-440, 200&

• 4) Miwa H : Life style in persons with functional gastrointestinai disorders--large-scale internet survey of lifestyle in Japan, Neurogastroenterol Motil 24 (5) : 464-471, 2012.

• 5) Feinle-Bisset C, Azpiroz F : Dietary and lifestyle factors in functional dyspepsia. Nat Rev Gastroenterol Hepatol 10 (3) : 150-157, 2013.
  pubmed

P.69 掲載の参考文献

• 1) 日本消化器病学会編 : 機能性消化管疾患診療ガイドライン 2014-機能性ディスペプシア (FD). 南江堂, 東京, 2014.

• 2) Moayyedi P, Soo S, Deeks J et al : Pharmacological interventions for non-ulcer dyspepsia Cochrane Database Syst Rev 4 : CD001960, 2006.
  pubmed

• 3) Geeraerts B, Tack J : Functional dyspepsia : past, Present, and future. J Gastroenterol 43 : 251-255, 2008.
  pubmed

• 4) Manabe N, Haruma K, Hata I et al : Clinical characteristics of Japanese dyspeptic patients : is the Rome III classification applicable? Scan J Gastroenterol 45 : 567-572, 2010.

• 5) Talley NJ, Vakil NB, Moayyedi P et al : American Gastroenterology Association technical review on the evaluation of dyspepsia. Gastroenterology 129 : 1756-1780, 2005.
  pubmed

P.74 掲載の参考文献

• 1) Moayyedi P, Soo S, Deeks J et al : Pharmacological interventions for non-ulcer dyspepsia (review). Cochrane Database of Systematic Reviews : CD001960, 2006.
  pubmed

• 2) Hiyama T, Haruma K : Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia. J Gastroenterol Hepatol 22 : 304-310, 2007.
  pubmed

• 3) Holtmann G, Talley NJ, Liebregts T et al : A placebo-controlled trial of itopride in functional dyspepsia. N Engl J Med 354 : 832-840, 2006.
  pubmed

• 4) Tally NJ, Tack J, Ptak T et al : Itopride in functional dyspepsia : results of two phase III multicenter, randomized, double-blind, placebo-controlled trials. Gut 57 : 740-746, 2008.

• 5) Hallerback BI, Bommelaer G, Bredberg E et al : Dose finding study of mosapride in functional dyspepsia : a placebo-controlled, randomized study. Aliment Pharmacol Ther 16 : 959-967, 2002.
  pubmed

• 6) Vakil N, Laine L, Tally NJ et al : Tegaserod treatment for dysmotility-like functional dyspepsia : results of two randomized, controlled trials. Am J Gastroenterol 103 : 1906-1919, 2008.

P.79 掲載の参考文献

• 1) Tack J, Talley NJ, Camilleri M et al : Functional gastroduodenal disorders. Gastroenterology 130 : 1466-1479, 2006.
  pubmed

• 2) 日本消化器病学会編 : 機能性消化管疾患診療ガイドライン 2014-機能性ディスペプシア (FD). 南江堂, 東京, 2014.

• 3) Matsueda K, Hongo M, Tack J et al : Clinical trial : dose-dependent therapeutic efficacy of acotiamide hydrochloride (Z-338) in patients with functional dyspepsia-100mg t. i. d. is an pitimal dosage. Neurogastroenterol Motil 22 : 618-626, 2010.

• 4) Matsueda K, Hongo M, Tack J et al : A placebo-controlled trial of acotiamide for meal-related symptoms of functional dyspepsia. Gut 61 : 821-828, 2012.
  pubmed

• 5) Matsueda K, Hongo M, Ushijima S et al : A long-term study of acotiamide in patients with functional dyspepsia : results from an open-label phase III trial in Japan on efficacy, safety and pattern of administration. Digestion 84 : 261-268, 2011.
  pubmed

• 6) TackJ, Masclee A, Headning R et al : A dose-ranging, p [acebo-controlled, pilot trial of acotiamide in patients with functional dyspepsia. Neurogastroenterol Motil 21 : 272-280, 2009.

• 7) Ogishima M, Kaibara M, Ueki S et al : Z-338 facilitates acetylcholine release from enteric neurons due to blockade of muscarinic autorecptors in guinea pig stomack. J Pharmacol Exp Ther 294 : 33-37, 2000.

• 8) Kawachi M, Matsunaga Y, Tanaka T et al : Acotiamide hydrochloride (Z-338) enhances gastric motility and emptying by inhibiting acetylcholinesterase activity in rats. Eur J Phamacol 666 : 218-225, 2011.

• 9) Matsunaga Y, Tanaka T, Yoshinaga K et al : Acotiamide Hydrochloride (Z-338), a new selective acetylcholinesterase inhibitor, enhances gastric motility without prolong QT interval dogs : comparison with cisapride, itopride, and mosapride. J Pharmacol Exp Ther 336 : 791-800, 2011.

• 10) Haruma K, Kusunoki H, Manabe N et al : Real-time assessment of gastroduodenal motility by ultrasonograpy. Digestion 77 (Suppl 1) : 48-51, 2008.

• 11) Kusunoki H, Haruma K, Manabe N et al : Therapeutic efficacy of acotiamide in patients with functional dyspepsia based on enhanced postprandial gastric accommodation and emptying : randomized controlled study evaluation by real-time ultrasonography. Neurogastroenterol Motil 24 : 540-547, 2012.
  pubmed

P.85 掲載の参考文献

• 1) Tatsuta M, Iishi H : Effect of treatment with liu-jun-zi-tang (TJ-43) on gastric emptying and gastrointestinal symptoms in dyspeptic patients. Aliment Pharmacol Ther 7 : 459-462, 1993.
  pubmed

• 2) Suzuki H, Matsuzaki J, Fukushima Y et al : Randomized clinical trial : rikkunshito in the treatment of functional dyspepsia-a multicenter, double-blind, randonlized, placebo-controlled study. Neurogastroenterol Motil 26 : 950-956, 2014.
  pubmed

• 3) Mogami S, Hattori T : Beneficial effects of rikkunshito, a Japanese kampo medicine, on gastrointestinal dysfunction and anorexia in combination with Western drug : a systematic review. Evid Based Complement Alternat Med 2014 [E-pub ahead of print].

• 4) Utumi Y. Iseki E, Murayama N et al : Effect of Rikkunshi-to on appetite loss found in elderly dementia patients : a preliminary study. Psychogeriatrics 11 : 34-39, 2011.
  pubmed

• 5) Kido T, Nakai Y, Kase Y et al : Effects of rikkunshi-to, a traditional Japanease medicine, on the delay of gastric emptying induced by N (G) -nitro-L-arginine. J Pharmacol Sci 98 : 161-167, 2005.

• 6) Hayakawa T, Arakawa T, Kase Y et al : Liu-Jun-Zi-Tang, a kampo medicine, promotes adaptive relaxation in isolated guine pig stomachs. Drugs Exp Clin Res 25 : 211-218, 1999.

• 7) Oikawa T, Ito G, Hoshino T et al : Hangekobokuto (Banxia-houpo-tang), a kampo medicine that treats functional dyspepsia. Evid Based Complement Alternat Med 6 : 375-378, 2009.
  pubmed

• 8) Kasahara Y, Saito E, Hikino H : Pharmacological actions of Pinellia Tuber and Zingiber Rhizomes. Shoyakugaku Zasshi 37 : 73-83, 1983.

• 9) Yamahara J, Huang Q, Li Y et al : Gastrointestinal motility-enhancingeffect of ginger and its active constituents. Chem Pharm Bull 38 : 430-431, 1990.

• 10) 楠裕明, 塚本真知, 山下直人ほか : 上腹部不定愁訴 (機能性ディスペプシア : FD) の現況とその漢方治療. 川崎医科大学総合臨床医学 37 : 97-106, 2011.

• 11) Suzuki H, Inadomi JM, Hibi T : Japanese herbal medicine in functional gastrointestinal disorders. Neurogastrointestinal Motil 21 : 688-696, 2009.

P.95 掲載の参考文献

• 1) Warren JR, Marshall BJ : Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet i : 1273-1275, 1983.

• 2) Asaka M, Kato M, Kudo M et al : Atrophic changes of gastric mucosa are caused by Helicobacter pylori infection rather than aging : studies in asymptomatic Japanese adults. Helicobacter 1 : 52-56, 1996.
  pubmed

• 3) Tack J, Talley NJ, Camilleri M et al : Functional Gastroduodenal Disorders. Gastroenterology 130 : 1466-1479, 2006.
  pubmed

• 4) Matsumoto Y, Ito M, Kamino D et al : Relation between histologic gastritis and gastric motility in Japanese patients with functional dyspepsia : evaluation by transabdominal ultrasonography. J Gastroenterol 43 : 332-337 (2008)
  pubmed

• 5) Scott AM, Kellow JE, Shuter B et al : Intragastric distribution and gastric emptying of solids and liquids in functional dyspepsia. Lack of influence of symptom subgroups and H. pylori-associated gastritis. Dig Dis Sci 38 : 2247-2254, 1993.

• 6) Mearin F, de Ribot X, Balboa A et al : Does Helicobacter pylori infection increase gastric sensitivity in functional dyspepsia? Gut 37 : 47-51, 1995.
  pubmed

• 7) Armstrong D : Helicobacter pylori infection and dyspepsia. Scand J Gastroenterol 215 (Suppl) 138-47, 1996.

• 8) Bernersen B, Johnsen R, Bostad L et al : Is Helicobacter pylori the cause of dyspepsia? BMJ 304 : 1276-1279, 1992.
  pubmed

• 9) Danesh J, Lawrence M, Murphy M et al : Systematic review of the epidemiological evidence on Helicobacter pylori infection and nonulcer or uninvestigated dyspepsia. Arch Intern Med 160 : 1192-1198, 2000.
  pubmed

• 10) Heikkinen M, Farkkila M : Long-term outcome of functional dyspepsia : effect of Helicobacter pylori infection. A 6- to 7-year follow-up study. Scand J Gastroenterol 37 : 905-910, 2002.
  pubmed

• 11) 日本消化器病学会編 : 機能性消化管疾患診療ガイドライン 2014-機能性ディスペプシア. 南江堂, 東京, 2014.

• 12) Suzuki H, Nishizawa T, Hibi T : Therapeutic strategies for functional dyspepsia and the introduction of th Rome III classification. J Gastroenterol 41 : 513-523, 2006.
  pubmed

• 13) Moayyedi P, Soo S, Deeks J et al : Systematic review and economic evaluation of Helicobacter pylori eradication treatment for non-ulcer dyspepsia. Dyspepsia Review Group. BMJ 321 : 659-664, 2000.
  pubmed

• 14) Moayyedi P, Soo S, Deeks J et al : Eradication of Helicobacter pylori for non-ulcer dyspepsia. Cochrane Database Syst Rev (2) : CD002096, 2006.
  pubmed

• 15) Laine L, Schoenfeld P, Fennerty MB. Therapy for Helicobacter pylori in patients with nonulcer dyspepsia. A meta-analysis of randomized, controlled trials. Ann Intern Med 134 (5) : 361-369, 2001.
  pubmed

• 16) Miwa H, Hirai S, Nagahara A et al : Cure of Helicobacter pylori infection does not improve symptoms in non-ulcer dyspepsia patients-a double-blind placebo-controlled study. Aliment Pharmacol Ther 14 : 317-324, 2000.

• 17) Azuma T, Ito Y, Suto H et al : The effect of Helicobacter pylori eradication therapy on dyspepsia symptoms in industrial workers in Japan. Aliment Pharmacol Ther 15 : 805-811, 2001.

• 18) Kamada T, Haruma K, Hata J et al : The long-term effect of Helicobacter pylori eradication therapy on symptoms in dyspeptic patients with fundic atrophic gastritis. Aliment Pharmacol Ther 18 : 245-252, 2003.

• 19) Jin X, Li YM : Systematic review and meta-analysis from Chinese literature : the association between Helicobacter pylori eradication and improvement of functional dyspepsia. Helicobacter 12 (5) : 541-546, 2007.
  pubmed

• 20) Gwee KA, Teng L, Wong RK et al : The response of Asian patients with functional dyspepsia to eradication of Helicobacter pylori infection. Eur J Gastroenterol Hepatol 21 (4) : 417-424, 2009.
  pubmed

• 21) Koskenpato J, Farkkila M, Sipponen P : Helicobacter pylori and different topographic types of gastritis : treatment response after successful eradication therapy in functional dyspepsia. Scand J Gastroenterol 37 : 778-784, 2002.
  pubmed

• 22) Kato S, Nishino Y, Ozawa K et al : The prevalence of Helicobacter pylori in Japanese children with gastritis or peptic ulcer disease. J Gastroenterol 39 : 734-738, 2004.

P.103 掲載の参考文献

• 1) Drossman DA : The functional gastrointestinal disorders and the Rome III process. Gastroenterology 130 : 1377-1390, 2006.
  pubmed

• 2) 福永幹彦, 石野振一郎, 中井吉英ほか : Functional Dyspepsia (FD). 心身症-診断・治療ガイドライン 2006 (小牧元, 久保千春, 福土審編). 協和企画, 東京, 2006, p. 42-62.

• 3) 金子宏 : ストレスと関連した心身症の最新の治療と展望. 日本内科学会雑誌 99 : 536-541, 2010.

• 4) 金子宏 : 機能性ディスペプシア. 心身医 50 : 931-938, 2010.
  Medical*Online

• 5) 金子宏, 坪井宏仁 : 機能性消化管障害からの提言. 日本心療内科学会誌 17 : 147-152, 2013.

• 6) Mimidis K, Tack J : Pathogenesis of dyspepsia. Dig Dis 26 : 194-202, 2008.
  pubmed

• 7) 福土審, 本郷道夫, 松枝啓監訳 : ROME III [日本語版] 機能性消化管障害. 協和企画, 東京, 2008, p. 591-597.

• 8) Owens DM, Nelson DK, Talley NJ : The irritable bowel syndrome : long-term prognosis and the physician-patient interaction. Ann Intern Med 122 : 107-112, 1995.
  pubmed

P.108 掲載の参考文献

• 1) Agreus L, Svardsudd K, Nyren O et al : Irritable bowel syndrome and dyspepsia in the general population : overlap and lack of stability over time. Gastroenterology 109 : 671-680, 1995.
  pubmed

• 2) Halder SL, Locke GR 3rd, Schleck CD et al : Natural history of functional gastrointestinal disorders : a 12-year longitudinal population-based study. Gastroenterology 133 : 799-807, 2007.
  pubmed

• 3) Talley NJ, Piper DW : The association between non-ulcer dyspepsia and other gastrointestinal disorders. Scand J Gastroenterol 20 : 896-900, 1985.
  pubmed

• 4) Kaji M, Fujiwara Y, Shiba M et al : Prevalence of overlaps between GERD, FD and IBS and impact on health-related quality of life. J Gastroenterol Hepatol 25 : 1151-1156, 2010.
  pubmed

• 5) Tack J, Caenepeel P, Arts J et al : Prevalence of acid reflux in functional dyspepsia and its association with symptom profile. Gut 54 : 1370-1376, 2005.
  pubmed

• 6) Neumann H, Monkemuller K, Kandulski A et al : Dyspepsia and IBS symptoms in patients with NERD, ERD and Barrett's esophagus. Dig Dis 26 : 243-247, 2008.
  pubmed

• 7) Ohara S. Kawano T, Kusano M et al : Survey on the prevalence of GERD and FD based on the Montreal definition and the Rome III criteria among patients presenting with epigastric symptoms in Japan. J Gastroenterol 46 : 603-611, 2011.
  pubmed

• 8) Nakajima S, Takahashi K, Sato J et al : Spectra of functional gastrointestinal disorders diagnosed by Rome III integrative questionnaire in a Japanese outpatient office and the impact of overlapping. J Gastroenterol Hepatol 25 (Suppl 1) : S138-143, 2010.

• 9) Wang A, Liao X, Xiong L et al : The clinical overlap between functional dyspepsia and irritable bowel syndrome based on Rome III criteria. BMC Gastroenterology 8 : 43, 2008.
  pubmed

IV 「困った FD 症例」とその診療の工夫

P.115 掲載の参考文献

• 1) 原澤茂, 三好秋馬, 三輪剛ほか : 運動不全型の上腹部愁訴 (dysmotility-like dyspepsia) に対するTJ-43六君子湯の多施設共同市販後臨床試験-二重盲検群間比較法による検討. 医学のあゆみ 187 : 207-229, 1998.

• 2) Oikawa T, Ito G, Hoshino T et al : Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia. Evid Based Complement Alternat Med 6 : 375-378, 2009.
  pubmed

• 3) Aro P, Talley NJ, Ronkainen J : Anxiety is associated with univestigated functional dyspepsia (Rome III criteria) in Swedish population-based study. Gastroenterology 137 : 94-100, 2009.

• 日本消化器病学会編 : 機能性消化管疾患診療ガイドライン 2014-機能性ディスペプシア (FD). 南江堂, 東京, 2014.

P.123 掲載の参考文献

• 1) Tack J. Talley NJ, Camilleri M et al : Functional gastroduodenal disorders. Gastroenterology 130 : 1466-1479, 2006,
  pubmed

• 2) Futagami S, Yamawaki H, Izumi N et al : Impact of sleep disorders in Japanese patients with functional dyspepsia (FD) : nizatidine improves clinical symptoms, gastric emptying and sleep disorders in FD patients. J Gastroenterol Hepatol 28 : 1314-1320, 2013.
  pubmed

• 3) Spiegel K, Tasail E, Penev P et al : Brief communication : Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med 141 : 846-850, 2004.

• 4) Hongo M : Epidemiology of FGID symptoms in Japanese general population with reference to life style. J Gastroenterol Hepatol 26 (Suppl 3) : 19-22, 2011.

• 5) Yamawaki H, Futagami S, Shimpuku M et al : Impact of sleep disorders, quality of life and gastric emptying in distinct subtypes of functional dyspepsia in Japan. J Neurogastroenterol Motil 20 : 104-112, 2014.
  pubmed

• 6) Spiller RC : Role of infection in irritable bowel syndrome. J Gastroenterol 42 : 41-47, 2007.
  pubmed

• 7) Mearin F, Perez-Oliveras M, Perello A et al : Dyspepsia and irritable bowel syndrome after a Salmonella gastroenteritis outbreak : one-year follow-up cohort study. Gastroenterology 129 : 98-104, 2005.
  pubmed

P.129 掲載の参考文献

• 1) Rasquin A, Lorenzo CD, Forbes D et al : Childhood functional gastrointestinal disorders : child/adolescent. Gastroenterology 130 : 1527-1537, 2006.

• 2) 福士審, 本郷道夫, 松枝啓監訳 : Rome III [日本語版]. 協和企画, 東京, 2008, pp. 183-230, 303-346, 429-478.

• 3) Kaminski A, Kamper A, Thaler K et al : Antidepressants for the treatment of abdominal pain-related functional gastrointestinal disorders in children and adolescents. Cochrane Database Syst Rev 6 : CD008013, 2011.
  pubmed

• 4) 日本小児心身医学会編 : 小児心身医学ガイドライン集-日常診療に活かす4つのガイドライン「くり返す子どもの痛みの理解と対応ガイドライン」. 南江堂, 東京, 2009.

• 5) Lindley KJ, Glaser D, Milla PJ : Consumerism in healthcare can be detrimental to child health : lessons from children with functional abdominal pain. Arch Dis Child 90 : 335-337, 2005.
  pubmed

P.136 掲載の参考文献

• 1) 三輪洋人 : 機i能性ディスペプシアの考え方. 日消誌 109 : 1683-1696, 2012.

• 2) Cheng C, Hui WM, Lam SK : Coping Style of Individuals With Functional Dyspepsia. Psychosom Med 61 : 789-795, 1999.

• 3) Cheng C, Hui WM, Lam SK : Psychosocial factors and perceived severity of functional dyspeptic symptoms : a psychosocial interactionist model. Psychosom Med 66 : 85-91, 2004.

• 4) Cheng C, Yang FC, Jun S : Flexible coping psychotherapy for functional dyspeptic patients : a randomized, controlled trial. Psychosom Med 69 : 81-88, 2007.