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書籍名	Year Book of RCC 2018
出版社	メディカルレビュー社
発行日	2018-12-31
著者	冨田善彦(編集) 金山博臣(編集) 植村天受(編集) 篠原信雄(編集)
ISBN	9784779221842
ページ数	150
版刷巻号	第1版第1刷
分野	臨床医学：内科腎臓
閲覧制限	未契約

腎細胞癌に関する現時点での知見と，現場の感覚を失わない「本当のところ」がわかる1冊。

目次

表紙
閲覧
序文
P.3閲覧
Contents
P.5閲覧
Color Gravure
P.8閲覧
Author List
P.10閲覧
[I] Round Table Discussion
P.11閲覧
[II] Topics of RCC～免疫チェックポイント阻害薬の副作用マネジメントの実際 ( IO - IO combinationを視野に入れて ) ～
P.19閲覧
- 1 症例の経験から ( 副作用の概観 )
- 2 各副作用のマネジメントの実際
[III] Risk factor up to date～リスク分類と1次治療選択～
P.73閲覧
- 1 基調論文 : 海外のMedical Oncologistに訊く
- 2 オピニオンリーダーに訊く
[IV] 付録
P.107閲覧
- RCC 関連演題の一覧 ( ASCO 2018, AUA 2018, ESMO 2018 )
- 索引
- 編集者プロフィール
奥付
閲覧

参考文献

[II] Topics of RCC～免疫チェックポイント阻害薬の副作用マネジメントの実際 ( IO - IO combinationを視野に入れて ) ～

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2) Howell M, et al. Optimal management of immune-related toxicities associated with checkpoint inhibitors in lung cancer. Lung Cancer. 2015 ; 88 : 117-23.
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2) Vansteenkiste J. Nivolumab for NSCLC in Japanese patients : similar benefits, but beware of pneumonitis. ESMO Open. 2017 ; 2 Suppl 1 : e000119.

3) Azuma A, et al. High Prevalence of Drug-induced Pneumonia in Japan. JMAJ. 2007 ; 50 : 405-11.

4) Larkin J, et al. Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma. N Engl J Med. 2015 ; 373 : 23-34.

5) 小野薬品工業株式会社/ブリストル・マイヤーズスクイブ株式会社. オプジーボ点滴静注適正使用に関する留意事項～間質性肺疾患の副作用について～. 2016-06. https://www.opdivo.jp/drug_info_files/drug_info/opdivo/tekisei/20000116/tekisei_pneumonia.pdf, (閲覧 : 2018-10-04)

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7) Naidoo J, et al. Pneumonitis in Patients Treated With Anti-Programmed Death-1/Programmed Death Ligand 1 Therapy. J Clin Oncol. 2017 ; 35 : 709-17.
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8) 日本呼吸器学会 (編). 薬剤性肺障害の診断・治療の手引き. 東京 : メディカルレビュー社 ; 2012.

9) Haanen JBAG, et al. Management of toxicities from immunotherapy : ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2017 ; 28 Suppl 4 : iv119-42.

10) Brahmer JR, et al. Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy : American Society of Clinical Oncology Clinical Practice Guideline. J Clin Oncol. 2018 ; 36 : 1714-68.

11) Pollack MH, et al. Safety of resuming anti-PD-1 in patients with immune-related adverse events (irAEs) during combined anti-CTLA-4 and anti-PD1 in metastatic melanoma. Ann Oncol. 2018 ; 29 : 250-5.
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12) Delaunay M, et al. Immune-checkpoint inhibitors associated with interstitial lung disease in cancer patients. Eur Respir J. 2017 ; 50. pii : 1700050.

13) Cho JY, et al. Characteristics, incidence, and risk factors of immune checkpoint inhibitor-related pneumonitis in patients with non-small cell lung cancer. Lung Cancer. 2018 ; 125 : 150-6.
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14) MSD株式会社/大鵬薬品工業株式会社. キイトルーダ(R) 市販直後調査の結果報告. 2017-10. https://www.msdconnect.jp/static/mcijapan/images/eppv_keytruda_201710.pdf, (閲覧 : 2018-10-0

P.43 掲載の参考文献

1) Brahmer JR, et al. Management of Immune-Related Adverse Events in Patients Treated with Immune Checkpoint Inhibitor Therapy : American Society of Clinical Oncology Clinical Practice Guideline. J Clin Onol. 2018 ; 36 : 1714-68.

2) Haanen JBAG, et al. Management of toxicities from immunotherapy : ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2017 ; 28 Suppl 4 : iv119-42.

3) Gupta A, et al. Systematic review : colitis associated with anti-CTLA-4 therapy. Aliment Pharmacol Ther. 2015 ; 42 : 406-17.
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4) Baxi S, et al. Immune-related adverse events for anti-PD-1 and anti-PD-L1 drugs : systematic review and meta-analysis. BMJ. 2018 ; 360 : k793.
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5) Weber JS, et al. Management of immune-related adverse events and kinetics of response with ipilimumab. J Clin Oncol. 2012 ; 30 : 2691-7.
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6) Kumar V, et al. Current Diagnosis and Management of Immune Related Adverse Events (irAEs) Induced by Immune Checkpoint Inhibitor Therapy. Front Pharmacol. 2017 ; 8 : 49.

7) Marthey L, et al. Cancer Immunotherapy with Anti-CTLA-4 Monoclonal Antibodies Induces an Inflammatory Bowel Disease. J Crohns Colitis. 2016 ; 10 : 395-401.
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8) Dubin K, et al. Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis. Nat Commun. 2016 ; 7 : 10391.
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9) Berman D, et al. Blockade of cytotoxic T-lymphocyte antigen-4 by ipilimumab results in dysregulation of gastrointestinal immunity in patients with advanced melanoma. Cancer Immun. 2010 ; 10 : 11.
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10) Bergqvist V, et al. Vedolizumab treatment for immune checkpoint inhibitor-induced enterocolitis. Cancer Immunol Immunother. 2017 ; 66 : 581-92.
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P.47 掲載の参考文献

1) Zen Y, et al. Hepatotoxicity of immune checkpoint inhibitors : a histology study of seven cases in comparison with autoimmune hepatitis and idiosyncratic drug-induced liver injury. Mod Pathol. 2018 ; 31 : 965-73.
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P.54 掲載の参考文献

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2) 日本循環器学会. 急性および慢性心筋炎の診断・治療に関するガイドライン (2009年改訂版). http://www.j-circ.or.jp/guideline/pdf/JCS2009_izumi_h.pdf, (閲覧 : 2018-10-25)

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7) Tajiri K, et al. Immune checkpoint inhibitor-related myocarditis. Jpn J Clin Oncol. 2018 ; 48 : 7-12.

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10) Tajmir-Riahi A, et al. Life-threatening Autoimmune Cardiomyopathy Reproducibly Induced in a Patient by Checkpoint Inhibitor Therapy. J Immunother. 2018 ; 41 : 35-8.

P.62 掲載の参考文献

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2) de Filette J, et al. Incidence of Thyroid-Related Adverse Events in Melanoma Patients Treated With Pembrolizumab. J Clin Endocrinol Metab. 2016 ; 101 : 4431-9.
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[III] Risk factor up to date～リスク分類と1次治療選択～

P.77 掲載の参考文献

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8) Miao D, et al. Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma. Science. 2018 ; 359 : 801-6.
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2) Wei SC, et al. Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade. Cell. 2017 ; 170 : 1120-33.e17.

3) Chen DS, et al. Elements of cancer immunity and the cancer-immune set point. Nature. 2017 ; 541 : 321-30.
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5) Study to Evaluate the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Axitinib Versus Sunitinib Monotherapy in Participants With Renal Cell Carcinoma (MK-3475-426/KEYNOTE-426). ClinicalTrials.gov Identifier : NCT02853331. https://clinicaltrials.gov/ct2/show/NCT02853331, (accessed 2018-10-18)

6) A Study of Atezolizumab in Combination With Bevacizumab Versus Sunitinib in Participants With Untreated Advanced Renal Cell Carcinoma (RCC) (IMmotion151). ClinicalTrials.gov Identifier : NCT02420821. https://clinicaltrials.gov/ct2/show/NCT02420821, (accessed 2018-10-18)

P.94 掲載の参考文献

1) Motzer RJ, et al. Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oncol. 2002 ; 20 : 289-96.
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2) Naito S, et al. Prognosis of Japanese metastatic renal cell carcinoma patients in the cytokine era : a cooperative group report of 1463 patients. Eur Urol. 2010 ; 57 : 317-25.

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2) National Comprehensive Cancer Network. NCCN Guidelines, Kidney Cancer, Version 2. 2019. https://www.nccn.org/professionals/physician_gls/default.aspx, (accessed 2018-10-25)

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3) Heng DY, et al. External validation and comparison with other models of the International Metastatic Renal-Cell Carcinoma Database Consortium prognostic model : a population-based study. Lancet Oncol. 2013 ; 14 : 141-8.

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7) Motzer RJ, et al. IMmotion 151 : A Randomized Phase III Study of Atezolizumab Plus Bevacizumab vs Sunitinib in Untreated Metastatic Renal Cell Carcinoma (mRCC) [abstract]. J Clin Oncol. 2018 ; 36 Suppl 6S : 578.

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15) McDermott DF, et al. Treatment-free interval (TFI) following discontinuation of first-line nivolumab plus ipilimumab (N+I) or sunitinib (S) in patients (Pts) with advanced renal cell carcinoma (aRCC) : CheckMate 214 analysis [abstract]. Ann Oncol. 2018 ; 29 Suppl 8 : 874P.

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