書籍詳細

CHAPTER 1 敗血症とは何なのか ?

P.5 掲載の参考文献

• 1) Balk RA, Bone RC. The septic syndrome. Definition and clinical implications. Crit Care Clin. 1989 ; 5 : 1-8.
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• 2) Bernard GR, Francois B, Mira JP, et al. Evaluating the efficacy and safety of two doses of the polyclonal anti-tumor necrosis factor-α fragment antibody AZD9773 in adult patients with severe sepsis and/or septic shock : randomized, double-blind, placebo-controlled phase IIb study. Crit Care Med. 2014 ; 42 : 504-11.

• 3) American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference : definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med. 1992 ; 20 : 864-74.
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• 4) Opal SM, Laterre PF, Francois B, et al ; ACCESS Study Group. Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis : the ACCESS randomized trial. JAMA. 2013 ; 309 : 1154-62.

CHAPTER 2 メカニズム

P.9 掲載の参考文献

• 1) Bone RC. Sir Isaac Newton, sepsis, SIRS, and CARS. Crit Care Med. 1996 ; 24 : 1125-8.

• 2) Osuchowski MF, Welch K, Siddiqui J, et al. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality. J Immunol. 2006 ; 177 : 1967-74.
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• 3) Xiao W, Mindrinos MN, Seok J, et al. Inflammation and host response to injury large-scale collaborative research program. A genomic storm in critically injured humans. J Exp Med. 2011 ; 208 : 2581-90.
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• 4) Hu D, Ren J, Wang G, et al. Persistent inflammation-immunosuppression catabolism syndrome, a common manifestation of patients with enterocutaneous fistula in intensive care unit. J Trauma Acute Care Surg. 2014 ; 76 : 725-9.
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CHAPTER 3 敗血症の定義

P.16 掲載の参考文献

• 1) Levy MM, Fink MP, Marshall JC, et al ; SCCM/ESICM/ACCP/ATS/SIS. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med. 2003 ; 31 : 1250-6.
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• 2) Zhao H, Heard SO, Mullen MT, et al. An evaluation of the diagnostic accuracy of the 1991 American College of Chest Physicians/Society of Critical Care Medicine and the 2001 Society of Critical Care Medicine/European Society of Intensive Care Medicine/American College of Chest Physicians/American Thoracic Society/Surgical Infection Society sepsis definition. Crit Care Med. 2012 ; 40 : 1700-6.
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• 3) Kaukonen KM, Bailey M, Pilcher D, et al. Systemic inflammatory response syndrome criteria in defining severe sepsis. N Engl J Med. 2015 ; 372 : 1629-38.
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• 4) Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016 ; 315 : 801-10.
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• 5) Seymour CW, Liu VX, Iwashyna TJ, et al. Assessment of clinical criteria for sepsis : For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016 ; 315 : 762-74.
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• 6) Raith EP, Udy AA, Bailey M, et al. Prognostic accuracy of the SOFA score, SIRS criteria, and qSOFA score for in-hospital mortality among adults with suspected infection admitted to the intensive care unit. JAMA. 2017 ; 317 : 290-300.

• 7) Dorsett M, Kroll M, Smith CS, et al. qSOFA has poor sensitivity for prehospital identification of severe sepsis and septic shock. Prehosp Emerg Care. 2017 ; 21 : 489-97.
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• 8) Askim A, Moser F, Gustad LT, et al. Poor performance of quick-SOFA (qSOFA) score in predicting severe sepsis and mortality-a prospective study of patients admitted with infection to the emergency department. Scand J Trauma Resusc Emerg Med. 2017 ; 25 : 56.

• 9) NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in blood pressure from 1975 to 2015 : a pooled analysis of 1479 population-based measurement studies with 19・1 million participants. Lancet. 2017 ; 389 : 37-55.

P.17 掲載の参考文献

• 1) Chen YX, Wang JY, Guo SB. Use of CRB-65 and quick Sepsis-related Organ Failure Assessment to predict site of care and mortality in pneumonia patients in the emergency department : a retrospective study. Crit Care. 2016 ; 20 : 167.
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CHAPTER 4 疫学・予後・認知度

P.20 掲載の参考文献

• 1) Fleischmann C, Scherag A, Adhikari NK, et al. Assessment of global incidence and mortality of hospital-treated sepsis. Current estimates and limitations. Am J Respir Crit Care Med. 2016 ; 193 : 259-72.
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• 2) 日本集中治療医学会Sepsis Registry委員会. 日本集中治療医学会第1回Sepsis Registry調査-2007年の重症敗血症および敗血症性ショックの診療結果報告. 日本集中治療医学会雑誌. 2013 ; 20 : 329-34.

• 3) Angus DC, Linde-Zwirble WT, Lidicker J, et al. Epidemiology of severe sepsis in the United States : analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001 ; 29 : 1303-10.
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• 4) Rhee C, Dantes R, Epstein L, et al ; CDC Prevention Epicenter Program. Incidence and trends of sepsis in US hospitals using clinical vs claims data, 2009-2014. JAMA. 2017 ; 318 : 1241-9.
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CHAPTER 5 診療ガイドラインの比較からみる諸外国の敗血症事情

P.26 掲載の参考文献

• 1) Rhodes A, Evans LE, Alhazzani W, et al. Surviving Sepsis Campaign : International Guidelines for Management of Sepsis and Septic Shock : 2016. Crit Care Med. 2017 ; 45 : 486-552.
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• 2) Guyatt GH, Schunemann HJ, Djulbegovic B, et al. Guideline panels should not GRADE good practice statements. J Clin Epidemiol. 2015 ; 68 : 597-600.

• 3) Nishida O, Ogura H, Egi M, et al. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016). Acute Med Surg. 2018 ; 5 : 3-89.
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• 4) Green RS, Djogovic D, Gray S, et al ; CAEP Critical Care Interest Group. Canadian Association of Emergency Physicians Sepsis Guidelines : the optimal management of severe sepsis in Canadian emergency departments. CJEM. 2008 ; 10 : 443-59.
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• 5) Tavare A, O'Flynn N. Recognition, diagnosis, and early management of sepsis : NICE guideline. Br J Gen Pract. 2017 ; 67 : 185-6.
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• 6) Greenhalgh DG, Saffle JR, Holmes JH 4th, et al. American Burn Association consensus conference to define sepsis and infection in burns. J Burn Care Res. 2007 ; 28 : 776-90.

CHAPTER 6 敗血症とメタ解析

P.29 掲載の参考文献

• 1) PROSPERO <https://www.crd.york.ac.uk/PROSPERO/> (2019/3/17にアクセス済)

• 2) Rayyan <https://rayyan.qcri.org/welcome> (2019/3/17にアクセス済)

• 3) Covidence <https://www.covidence.org/home> (2019/3/17にアクセス済)

• 4) PRISMA <http://www.prisma-statement.org/> (2019/3/17にアクセス済)

• 5) Kondo Y, Umemura Y, Hayashida K, et al. Diagnostic value of procalcitonin and presepsin for sepsis in critically ill adult patients : a systematic review and meta-analysis. J Intensive Care. 2019 ; 7 : 22.

CHAPTER 7 診断・重症度マーカー

P.34 掲載の参考文献

• 1) Schuetz P, Birkhahn R, Sherwin R, et al. Serial procalcitonin predicts mortality in severe sepsis patients : results from the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study. Crit Care Med. 2017 ; 45 : 781-9.
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• 2) Trasy D, Molnar Z. Procalcitonin-Assisted antibiotic strategy in sepsis. EJIFCC. 2017 ; 28 : 104-13.
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• 3) de Jong E, van Oers JA, Beishuizen A, et al. Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients : a randomised, controlled, open-label trial. Lancet Infect Dis. 2016 ; 16 : 819-27.
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• 4) Liu Y, Hou JH, Li Q, et al. Biomarkers for diagnosis of sepsis in patients with systemic inflammatory response syndrome : a systematic review and meta-analysis. Springerplus. 2016 ; 5 : 2091.
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• 5) Klouche K, Cristol JP, Devin J, et al. Diagnostic and prognostic value of soluble CD14 subtype (Presepsin) for sepsis and community-acquired pneumonia in ICU patients. Ann Intensive Care. 2016 ; 6 : 59.
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• 6) Bomberg H, Klingele M, Wagenpfeil S, et al. Presepsin (sCD14-ST) is a novel marker for risk stratification in cardiac surgery patients. Anesthesiology. 2017 ; 126 : 631-42.
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• 7) Rios-Toro JJ, Marquez-Coello M, Garcia-Alvarez JM, et al. Soluble membrane receptors, interleukin 6, procalcitonin and C reactive protein as prognostic markers in patients with severe sepsis and septic shock. PLoS One. 2017 ; 12 : e0175254.

CHAPTER 8 敗血症の身体所見

P.38 掲載の参考文献

• 1) Gadomski AM, Permutt T, Stanton B. Correcting respiratory rate for the presence of fever. J Clin Epidemiol. 1994 ; 47 : 1043-9.
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CHAPTER 9 敗血症の問診・カルテの書き方

P.42 掲載の参考文献

• 1) Arens C, Bajwa SA, Koch C, et al. Sepsis-induced long-term immune paralysis-results of a descriptive, explorative study. Crit Care. 2016 ; 20 : 93.
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• 2) Sun A, Netzer G, Small DS, et al. Association between index hospitalization and hospital readmission in sepsis survivors. Crit Care Med. 2016 ; 44 : 478-87.
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CHAPTER 10 外傷後敗血症

P.47 掲載の参考文献

• 1) Wafaisade A, Lefering R, Bouillon B, et al. Epidemiology and risk factors of sepsis after multiple trauma : an analysis of 29,829 patients from the Trauma Registry of the German Society for Trauma Surgery. Crit Care Med. 2011 ; 39 : 621-8.
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• 2) Trentzsch H, Lefering R, Nienaber U, et al. The role of biological sex in severely traumatized patients on outcomes : a matched-pair analysis. Ann Surg. 2015 ; 261 : 774-80.
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• 3) Pandya A, Chaput KH, Schertzer A, et al. Risk of infection and sepsis in pediatric patients with traumatic brain injury admitted to hospital following major trauma. Sci Rep. 2018 ; 8 : 9798.
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• 4) Park JH, Choi SH, Yoon YH, et al. Risk factors for sepsis in Korean trauma patients. Eur J Trauma Emerg Surg. 2016 ; 42 : 453-8.
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CHAPTER 11 熱傷後敗血症

P.53 掲載の参考文献

• 1) 日本熱傷学会学術委員会, 編. 熱傷診療ガイドライン 改訂第2版. 73-4, 2015.

• 2) Porter C, Tompkins RG, Finnerty CC, et al. The metabolic stress response to burn trauma : current understanding and therapies. Lancet. 2016 ; 388 : 1417-26.
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CHAPTER 12 軟部組織感染による敗血症

P.58 掲載の参考文献

• 1) Riseman JA, Zamboni WA, Curtis A, et al. Hyperbaric oxygen therapy for necrotizing fasciitis reduces mortality and the need for debridements. Surgery. 1990 ; 108 : 847-50.
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• 2) Wong CH, Khin LW, Heng KS, et al. The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score : a tool for distinguishing necrotizing fasciitis from other soft tissue infections. Crit Care Med. 2004 ; 32 : 1535-41.

• 3) Fournier JA. Jean-Alfred Fournier 1832-1914. Gangrene foudroyante de la verge (overwhelming gangrene). Sem Med 1883. Dis Colon Rectum, 1988 ; 31 : 984-8.

CHAPTER 13 敗血症関連心停止

P.62 掲載の参考文献

• 1) Morgan RW, Fitzgerald JC, Weiss SL, et al. Sepsis-associated in-hospital cardiac arrest : epidemiology, pathophysiology, and potential therapies. J Crit Care. 2017 ; 40 : 128-35.
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• 2) Bagate F, Razazi K, Boissier F, et al. Association between relative adrenal insufficiency and septic cardiomyopathy : a preliminary report. Intensive Care Med. 2017 ; 43 : 1924-6.
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• 3) Parker MM, Shelhamer JH, Bacharach SL, et al. Profound but reversible myocardial depression in patients with septic shock. Ann Intern Med. 1984 ; 100 : 483-90.
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• 4) Mehta NJ, Khan IA, Gupta V, et al. Cardiac troponin I predicts myocardial dysfunction and adverse outcome in septic shock. Int J Cardiol. 2004 ; 95 : 13-7.
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CHAPTER 14 敗血症関連脳症

P.66 掲載の参考文献

• 1) Siami S, Annane D, Sharshar T. The encephalopathy in sepsis. Crit Care Clin. 2008 ; 24 : 67-82.
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• 2) Kuperberg SJ, Wadgaonkar R. Sepsis-associated encephalopathy : the blood-brain barrier and the sphingolipid rheostat. Front Immunol. 2017 ; 8 : 597.
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• 3) Sonneville R, de Montmollin E, Poujade J, et al. Potentially modifiable factors contributing to sepsis-associated encephalopathy. Intensive Care Med. 2017 ; 43 : 1075-84.
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CHAPTER 15 モニター

P.71 掲載の参考文献

• 1) Gorges M, Markewitz BA, Westenskow DR. Improving alarm performance in the medical intensive care unit using delays and clinical context. Anesth Analg. 2009 ; 108 : 1546-52.
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• 2) Michard F. Changes in arterial pressure during mechanical ventilation. Anesthesiology. 2005 ; 103 : 419-28.
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• 3) Leone M, Asfar P, Radermacher P, et al. Optimizing mean arterial pressure in septic shock : a critical reappraisal of the literature. Crit Care. 2015 ; 19 : 101.

CHAPTER 16 輸液

P.74 掲載の参考文献

• 1) 日本集中治療医学会, 日本救急医学会, 編. 日本版敗血症診療ガイドライン 2016 (J-SSCG 2016) ダイジェスト版. 真興交易医書出版部 ; 2017. p. 66-7.

• 2) Nunes TS, Ladeira RT, Bafi AT, et al. Duration of hemodynamic effects of crystalloids in patients with circulatory shock after initial resuscitation. Ann Intensive Care. 2014 ; 4 : 25.
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• 3) Haase N, Perner A, Hennings LI, et al. Hydroxyethyl starch 130/0.38-0.45 versus crystalloid or albumin in patients with sepsis : systematic review with meta-analysis and trial sequential analysis. BMJ. 2013 ; 346 : f839.
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CHAPTER 17 抗菌薬治療

P.81 掲載の参考文献

• 1) Kumar A, Ellis P, Arabi Y, et al. Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock. Chest. 2009 ; 136 : 1237-48.

• 2) Charbonneau P, Parienti JJ, Thibon P, et al. Fluoroquinolone use and methicillin-resistant Staphylococcus aureus isolation rates in hospitalized patients : a quasi experimental study. Clin Infect Dis. 2006 ; 42 : 778-84.
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• 3) Paul M, Lador A, Grozinsky-Glasberg S, et al. Beta lactam antibiotic monotherapy versus beta lactam-aminoglycoside antibiotic combination therapy for sepsis. Cochrane Database Syst Rev. 2014 ; (1) : CD003344.
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• 4) Alam N, Oskam E, Stassen PM, et al. Prehospital antibiotics in the ambulance for sepsis : a multicentre, open label, randomised trial. Lancet Respir Med. 2018 ; 6 : 40-50.
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• 5) Menees DS, Peterson ED, Wang Y, et al. Door-to-balloon time and mortality among patients undergoing primary PCI. N Engl J Med. 2013 ; 369 : 901-9.
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CHAPTER 18 抗ウイルス薬治療

P.86 掲載の参考文献

• 1) Southeast Asia Infectious Disease Clinical Research Network. Causes and outcomes of sepsis in southeast Asia : a multinational multicentre cross-sectional study. Lancet Glob Health. 2017 ; 5 : e157-67.
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• 2) Fadila MF, Wool KJ. Rhabdomyolysis secondary to influenza a infection : a case report and review of the literature. N Am J Med Sci. 2015 ; 7 : 122-4.
  pubmed

• 3) Walton AH, Muenzer JT, Rasche D, et al. Reactivation of multiple viruses in patients with sepsis. PLoS One. 2014 ; 9 : e98819.
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• 4) Limaye AP, Kirby KA, Rubenfeld GD, et al. Cytomegalovirus reactivation in critically ill immunocompetent patients. JAMA. 2008 ; 300 : 413-22.
  pubmed

CHAPTER 19 抗真菌薬治療

P.90 掲載の参考文献

• 1) 日本医真菌学会. 侵襲性カンジダ症の診断・治療ガイドライン. <http://www.jsmm.org/index.html> (2019. 2. 1 アクセス済)

CHAPTER 20 ドレナージ治療

P.94 掲載の参考文献

• 1) Beger HG, Bittner R, Block S, et al. Bacterial contamination of pancreatic necrosis. A prospective clinical study. Gastroenterology. 1986 ; 91 : 433-8.
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• 2) Siu LK, Yeh KM, Lin JC, et al. Klebsiella pneumoniae liver abscess : a new invasive syndrome. Lancet Infect Dis. 2012 ; 12 : 881-7.
  pubmed

• 3) Rahimian J, Wilson T, Oram V, et al. Pyogenic liver abscess : recent trends in etiology and mortality. Clin Infect Dis. 2004 ; 39 : 1654-9.
  pubmed

P.96 掲載の参考文献

• 1) Naito T, Torikai K, Mizooka M, et al. Relationships between causes of fever of unknown origin and inflammatory markers : a multicenter collaborative retrospective study. Intern Med. 2015 ; 54 : 1989-94.
  pubmed

• 2) Arnow PM, Flaherty JP. Fever of unknown origin. Lancet. 1997 ; 350 : 575-80.
  pubmed

CHAPTER 21 循環作動薬

P.99 掲載の参考文献

• 1) Nadeem R, Sockanathan S, Singh M, et al. Impact of dobutamine in patients with septic shock : a meta-regression analysis. Am J Ther. 2017 ; 24 : e333-46.
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• 2) Hayes MA, Timmins AC, Yau EH, et al. Elevation of systemic oxygen delivery in the treatment of critically ill patients. N Engl J Med. 1994 ; 330 : 1717-22.
  pubmed

• 3) Russell JA, Walley KR, Singer J, et al. Vasopressin versus norepinephrine infusion in patients with septic shock. N Engl J Med. 2008 ; 358 : 877-87.
  pubmed

• 4) Chidambaram S, Goh EL, Rey VG, et al. Vasopressin vs noradrenaline : have we found the perfect recipe to improve outcome in septic shock? J Crit Care. 2019 ; 49 : 99-104.
  pubmed

• 5) Chen HH, Anstrom KJ, Givertz MM, et al. Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction : the ROSE acute heart failure randomized trial. JAMA. 2013 ; 310 : 2533-43.

• 6) Unger M, Morelli A, Singer M, et al. Landiolol in patients with septic shock resident in an intensive care unit (LANDI-SEP) : study protocol for a randomized controlled trial. Trials. 2018 ; 19 : 637.

P.100 掲載の参考文献

• 1) Kuipers S, Klein Klouwenberg PM, Cremer OL. Incidence, risk factors and outcomes of new-onset atrial fibrillation in patients with sepsis : a systematic review. Crit Care. 2014 ; 18 : 688.
  pubmed

CHAPTER 22 ECMO

P.105 掲載の参考文献

• 1) MacLaren G, Pellegrino V, Butt W, et al. Successful use of ECMO in adults with life-threatening infections. Anaesth Intensive Care. 2004 ; 32 : 707-10.
  pubmed

• 2) Brechot N, Luyt CE, Schmidt M, et al. Venoarterial extracorporeal membrane oxygenation support for refractory cardiovascular dysfunction during severe bacterial septic shock. Crit Care Med. 2013 ; 41 : 1616-26.
  pubmed

• 3) Huang CT, Tsai YJ, Tsai PR, et al. Extracorporeal membrane oxygenation resuscitation in adult patients with refractory septic shock. J Thorac Cardiovasc Surg. 2013 ; 146 : 1041-6.
  pubmed

• 4) Ro SK, Kim WK, Lim JY, et al. Extracorporeal life support for adults with refractory septic shock. Thoracic Cardiovasc Surg. 2018 ; 156 : 1104-9.
  pubmed

• 5) Gail MA, William RL, Graeme ML, et al. ECMO : Extracorporeal Cardiopulmonary Support in Critical Care, 4th edition. ELSO. 2015.

• 6) Murray JF, Matthay MA, Luce JM, et al. An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis. 1988 ; 138 : 720-3.
  pubmed

CHAPTER 23 敗血症性ARDSと人工呼吸管理

P.110 掲載の参考文献

• 1) Ognibene FP, Martin SE, Parker MM, et al. Adult respiratory distress syndrome in patients with severe neutropenia. N Engl J Med. 1986 ; 315 : 547-51.
  pubmed

• 2) Zeiher BG, Artigas A, Vincent JL, et al. Neutrophil elastase inhibition in acute lung injury : results of the STRIVE study. Crit Care Med. 2004 ; 32 : 1695-702.
  pubmed

• 3) Amato MB, Meade MO, Slutsky AS, et al. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med. 2015 : 372 : 747-55.
  pubmed

• 4) Toufen Junior C, De Santis Santiago RR, Hirota AS, et al. Driving pressure and long-term outcomes in moderate/severe acute respiratory distress syndrome. Ann Intensive Care. 2018 ; 8 : 119.
  pubmed

CHAPTER 24 鎮痛と鎮静

P.117 掲載の参考文献

• 1) 日本集中治療医学会J-PADガイドライン作成委員会. 日本版・集中治療室における成人重症患者に対する痛み・不穏・せん妄のための臨床ガイドライン. 日集中医誌. 2014 ; 21 : 539-79.

• 2) Sessler CN, Gosnell MS, Grap MJ, et al. The Richmond Agitation-Sedation Scale : validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med. 2002 ; 166 : 1338-44.
  pubmed

• 3) Whaley L. Nursing care of infants and children 3rd edition. Mosby ; 1987.

• 4) Clinical practice guidelines for the prevention and management of pain, agitation/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU. Crit Care Med. 2018 ; 46 : 825-73.

CHAPTER 25 腎代替療法

P.120 掲載の参考文献

• 1) Forni LG, Ricci Z, Ronco C, et al. Extracorporeal renal replacement therapies in the treatment of sepsis : where are we? Semin Nephrol. 2015 ; 35 : 55-63.
  pubmed

• 2) Wang X, Jie Yuan W. Timing of initiation of renal replacement therapy in acute kidney injury : a systematic review and meta-analysis. Ren Fail. 2012 ; 34 : 396-402.

• 3) Barbar SD, Clere-Jehl R, Bourredjem A, et al. Timing of renal-replacement therapy in patients with acute kidney injury and sepsis. N Engl J Med. 2018 ; 379 : 1431-42.
  pubmed

• 4) Jun M, Heerspink HJ, Ninomiya T, et al. Intensities of renal replacement therapy in acute kidney injury : a systematic review and meta-analysis. Clin J Am Soc Nephrol. 2010 ; 5 : 956-63.
  pubmed

CHAPTER 26 造影剤腎症と敗血症性腎障害

P.123 掲載の参考文献

• 1) Tao SM, Kong X, Schoepf UJ, et al. Acute kidney injury in patients with nephrotic syndrome undergoing contrast-enhanced CT for suspected venous thromboembolism : a propensity score-matched retrospective cohort study. Eur Radiol. 2018 ; 28 : 1585-93.
  pubmed

• 2) Levy EM, Viscoli CM, Horwitz RI. The effect of acute renal failure on mortality. A cohort analysis. JAMA. 1996 ; 275 : 1489-94.
  pubmed

CHAPTER 27 サイトカイン・エンドトキシン吸着

P.127 掲載の参考文献

• 1) Wagenlehner FME, Pilatz A, Weidner W, et al. Urosepsis : overview of the diagnostic and treatment challenges. Microbiol Spectr. 2015 ; 3. doi : 10.1128/microbiolspec.UTI-0003-2012

• 1) Aoki H, Kodama M, Tani T, et al. Treatment of sepsis by extracorporeal elimination of endotoxin using polymyxin B-immobilized fiber. Am J Surg. 1994 ; 167 : 412-7.
  pubmed

• 2) Cruz DN, Antonelli M, Fumagalli R, et al. Early use of polymyxin B hemoperfusion in abdominal septic shock : the EUPHAS randomized controlled trial. JAMA. 2009 ; 301 : 2445-52.
  pubmed

• 3) Payen DM, Guilhot J, Launey Y, et al. Early use of polymyxin B hemoperfusion in patients with septic shock due to peritonitis : a multicenter randomized control trial. Intensive Care Med. 2015 ; 41 : 975-84.
  pubmed

• 4) Dellinger RP, Bagshaw SM, Antonelli M, et al. Effect of targeted polymyxin B hemoperfusion on 28-day mortality in patients with septic shock and elevated endotoxin level : the EUPHRATES randomized clinical trial. JAMA. 2018 ; 320 : 1455-63.
  pubmed

• 5) Shiga H, Hirasawa H, Nishida O, et al. Continuous hemodiafiltration with a cytokine-adsorbing hemofilter in patients with septic shock : a preliminary report. Blood Purif. 2014 ; 38 : 211-8.
  pubmed

• 6) Schetz M, Van Cromphaut S, Dubois J, et al. Does the surface-treated AN69 membrane prolong filter survival in CRRT without anticoagulation? Intensive Care Med. 2012 ; 38 : 1818-25.
  pubmed

CHAPTER 28 輸血

P.131 掲載の参考文献

• 1) Holst LB, Haase N, Wetterslev J, et al. Lower versus higher hemoglobin threshold for transfusion in septic shock. N Engl J Med. 2014 ; 371 : 1381-91.
  pubmed

• 2) Fernandes CJ Jr, Akamine N, De Marco FV, et al. Red blood cell transfusion does not increase oxygen consumption in critically ill septic patients. Crit Care. 2001 ; 5 : 362-7.

• 3) Gajic O, Dzik WH, Toy P. Fresh frozen plasma and platelet transfusion for nonbleeding patients in the intensive care unit : benefit or harm? Crit Care Med. 2006 ; 34 : S170-3.
  pubmed

CHAPTER 29 栄養

P.135 掲載の参考文献

• 1) Arabi YM, Aldawood AS, Haddad SH, et al. Permissive underfeeding or standard enteral feeding in critically ill adults. N Engl J Med. 2015 ; 372 : 2398-408.

• 2) Casaer MP, Mesotten D, Hermans G, et al. Early versus late parenteral nutrition in critically ill adults. N Engl J Med. 2011 ; 365 : 506-17.
  pubmed

• 3) Wei Y, Yang J, Wang J, et al. Successful treatment with fecal microbiota transplantation in patients with multiple organ dysfunction syndrome and diarrhea following severe sepsis. Crit Care. 2016 ; 20 : 332.

CHAPTER 30 血糖コントロール

P.138 掲載の参考文献

• 1) NICE-SUGAR Study Investigators. Intensive versus conventional glucose control in critically ill patients. N Engl J Med. 2009 ; 360 : 1283-97.

• 2) Hermanides J, Vriesendorp TM, Bosman RJ, et al. Glucose variability is associated with intensive care unit mortality. Crit Care Med. 2010 ; 38 : 838-42.
  pubmed

CHAPTER 31 敗血症と補体

P.142 掲載の参考文献

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• 3) Robertson N, Rappas M, Dore AS, et al. Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727. Nature. 2018 ; 553 : 111-4.

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CHAPTER 32 敗血症性DIC

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• 2) Manson JM, Smith RJ, Wilmore DW. Growth hormone stimulates protein synthesis during hypocaloric parenteral nutrition : role of hormonal-substrate environment. Ann Surg. 1988 ; 208 : 136-42.
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CHAPTER 33 ステロイド補充療法

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• 1) Cooperative Study Group. The effectiveness of hydrocortisone in the management of severe infections : a double-blind study. JAMA. 1963 ; 183 : 462-5.

• 2) Sprung CL, Caralis PV, Marcial EH, et al. The effects of high-dose corticosteroids in patients with septic shock. A prospective, controlled study. N Engl J Med. 1984 ; 311 : 1137-43.
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• 4) Didier K, Evelyn T, Gernot M, et al. Effect of hydrocortisone on development of shock among patients with severe sepsis. The HYPRESS Randomized Clinical Trial. JAMA. 2016 ; 316 : 1775-85.

• 5) Annane D, Renault A, Brun-Buisson C, et al. Hydrocortisone plus fludrocortisone for adults with septic shock. N Engl J Med. 2018 ; 378 : 809-18.
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CHAPTER 34 高気圧酸素療法

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• 1) Chiang IH, Chen SG, Huang KL, et al. Adjunctive hyperbaric oxygen therapy in severe burns : experience in Taiwan Formosa Water Park dust explosion disaster. Burns. 2017 ; 43 : 852-7.
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• 2) Bessereau J, Aboab J, Hullin T, et al. Safety of hyperbaric oxygen therapy in mechanically ventilated patients. Int Marit Health. 2017 ; 68 : 46-51.
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• 3) Weaver LK. Hyperbaric oxygen in the critically ill. Crit Care Med. 2011 ; 39 : 1784-91.
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CHAPTER 35 深部静脈血栓症予防

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• 1) Kaplan D, Casper TC, Elliott CG, et al. VTE incidence and risk factors in patients with severe sepsis and septic shock. Chest. 2015 ; 148 : 1224-30.
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• 2) Kassim NA, Farid TM, Pessar SA, et al. Performance evaluation of different D-dimer cutoffs in bedridden hospitalized elderly patients. Clin Appl Thromb Hemost. 2017 ; 23 : 998-1004.
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• 1) Anand SS, Wells PS, Hunt D, et al. Does this patient have deep vein thrombosis? JAMA. 1998 ; 279 : 1094-9.
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CHAPTER 36 上部消化管潰瘍の予防

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• 2) Barletta JF, Kanji S, MacLaren R, et al. Pharmacoepidemiology of stress ulcer prophylaxis in the United States and Canada. J Crit Care. 2014 ; 29 : 955-60.

• 3) Alhazzani W, Alenezi F, Jaeschke RZ, et al. Proton pump inhibitors versus histamine 2 receptor antagonists for stress ulcer prophylaxis in critically ill patients : a systematic review and meta-analysis. Crit Care Med. 2013 ; 41 : 693-705.
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• 4) MacLaren R, Reynolds PM, Allen RR. Histamine-2 receptor antagonists vs proton pump inhibitors on gastrointestinal tract hemorrhage and infectious complications in the intensive care unit. JAMA Intern Med. 2014 ; 174 : 564-74.
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CHAPTER 37 社会復帰と再発

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• 1) Needham DM, Davidson J, Cohen H, et al. Improving long-term outcomes after discharge from intensive care unit : report from a stakeholders' conference. Crit Care Med. 2012 ; 40 : 502-9.
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• 2) Shen HN, Lu CL, Yang HH. Risk of recurrence after surviving severe sepsis : a matched cohort study. Crit Care Med. 2016 ; 44 : 1833-41.
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• 3) Guirgis FW, Brakenridge S, Sutchu S, et al. The long-term burden of severe sepsis and septic shock : sepsis recidivism and organ dysfunction. J Trauma Acute Care Surg. 2016 ; 81 : 525-32.

• 4) von Bahr V, Hultman J, Eksborg S, et al. Long-term survival in adults treated with extracorporeal membrane oxygenation for respiratory failure and sepsis. Crit Care Med. 2017 ; 45 : 164-70.
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• 1) Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975 ; 12 : 189-98.

• 2) Gusmao-Flores D, Salluh JI, Chalhub RA, et al. The confusion assessment method for the intensive care unit (CAM-ICU) and intensive care delirium screening checklist (ICDSC) for the diagnosis of delirium : a systematic review and meta-analysis of clinical studies. Crit Care. 2012 ; 16 : R115.
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CHAPTER 38 小児敗血症

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• 1) Schlapbach LJ, Straney L, Bellomo R, et al. Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit. Intensive Care Med. 2018 ; 44 : 179-88.

• 2) Evans IVR, Phillips GS, Alpern ER, et al. Association between the New York sepsis care mandate and in-hospital mortality for pediatric sepsis. JAMA. 2018 ; 320 : 358-67.
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• 3) 横川真理, 笠井正志, 志馬伸朗. 本邦小児集中治療領域における敗血症性ショック管理の現状. 日集中医誌. 2018 ; 25 : 115-20.

• 4) Ventura AM, Shieh HH, Bousso A, et al. Double-blind prospective randomized controlled trial of dopamine versus epinephrine as first-line vasoactive drugs in pediatric septic shock. Crit Care Med. 2015 ; 43 : 2292-302.
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CHAPTER 39 人工知能と敗血症治療

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• 1) Nemati S, Holder A, Razmi F, et al. An interpretable machine learning model for accurate prediction of sepsis in the ICU. Crit Care Med. 2018 ; 46 : 547-53.
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• 2) Kamaleswaran R, Akbilgic O, Hallman MA, et al. Applying artificial intelligence to identify physiomarkers predicting severe sepsis in the PICU. Pediatr Crit Care Med. 2018 ; 19 : e495-503.

• 3) Komorowski M, Celi LA, Badawi O, et al. The artificial intelligence clinician learns optimal treatment strategies for sepsis in intensive care. Nat Med. 2018 ; 24 : 1716-20.
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• 1) Singhal A, Rogers EM. Entertainment education : a communication strategy for social change. Mahwah and London : Lawrence Erlbaum ; 1999.

CHAPTER 40 敗血症バンドル治療の変遷

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• 2) Osborn TM. Severe sepsis and septic shock trials (ProCESS, ARISE, ProMISe) : what is optimal resuscitation? Crit Care Clin. 2017 ; 33 : 323-44.
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• 3) Lu Y, Zhang H, Teng F, et al. Early goal-directed therapy in severe sepsis and septic shock : a meta-analysis and trial sequential analysis of randomized controlled trials. J Intensive Care Med. 2018 ; 33 : 296-309.
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• 4) Jansen TC, van Bommel J, Schoonderbeek FJ, et al. Early lactate-guided therapy in intensive care unit patients : a multicenter, open-label, randomized controlled trial. Am J Respir Crit Care Med. 2010 ; 182 : 752-61.
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• 5) Levy MM, Evans LE, Rhodes A. The surviving sepsis campaign bundle : 2018 update. Crit Care Med. 2018 ; 46 : 997-1000.
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CHAPTER 41 医学英語論文の書き方

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• 1) Hurst SA. Declaration of Helsinki and protection for vulnerable research participants. JAMA. 2014 ; 311 : 1252.
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