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DRUG METABOLISM AND PHARMACOKINETICS 22巻 4号

発行元
日本薬物動態学会
ISSN
1347-4367
ISSN(オンライン)
1880-0920
前雑誌
薬物動態

書籍情報から探す
開始頁
Solubility and Dissolution Profile Assessment in Drug Discovery
Kiyohiko SUGANO, Arimichi OKAZAKI, Shohei SUGIMOTO, Sumitra TAVORNVIPAS, Atsushi OMURA, Takashi MANO
Global Research & Development, Nagoya Laboratories, Pharmaceutical R&D, Pfizer Inc., Aichi, Japan
DRUG METABOLISM AND PHARMACOKINETICS 22 (4) 225-254, 2007.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Altered Expression of Basement Membrane-related Molecules in Rat Brain Pericyte, Endothelial, and Astrocyte Cell Lines after Transforming Growth Factor-β1 Treatment
Noriko KOSE1, Tomoko ASASHIMA1, 2, 3, 4, Mariko MUTA1, Hisashi IIZASA1, 5, Yoshimichi SAI1, Tetsuya TERASAKI2, 3, 4, Emi NAKASHIMA1
1Department of Pharmaceutics, Kyoritsu University of Pharmacy, Tokyo, Japan, 2CREST, Japan Science and Technology Corporation (JST) Japan, 3Department of Molecular Biopharmacy and Genetics, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan, 4New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan, 5The Wistar Institute, Philadelphia, USA
DRUG METABOLISM AND PHARMACOKINETICS 22 (4) 255-266, 2007.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Inhibitory Effects of Angiotensin Receptor Blockers on CYP2C9 Activity in Human Liver Microsomes
Emi KAMIYAMA, Yasushi YOSHIGAE, Atsushi KASUYA, Makoto TAKEI, Atsushi KURIHARA, Toshihiko IKEDA
Drug Metabolism and Pharmacokinetics Research Laboratories, Sankyo Co., Ltd., Tokyo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 22 (4) 267-275, 2007.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Broad but Distinct Role of Pregnane X Receptor on the Expression of Individual Cytochrome P450s in Human Hepatocytes
Koki KOJIMA1, 2, Kiyoshi NAGATA1, 3, Tsutomu MATSUBARA1, Yasushi YAMAZOE1
1Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Miyagi, Japan, 2Exploratory Toxicology & DMPK Research Laboratories, Tanabe Seiyaku Co., Ltd., 3Tohoku Pharmaceutical University
DRUG METABOLISM AND PHARMACOKINETICS 22 (4) 276-286, 2007.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Role of Human Hepatocyte Nuclear Factor 4α in the Expression of Drug-Metabolizing Enzymes and Transporters in Human Hepatocytes Assessed by Use of Small Interfering RNA
Yoshiteru KAMIYAMA1, 2, Tsutomu MATSUBARA1, 3, Kouichi YOSHINARI1, Kiyoshi NAGATA1, 4, Hidetaka KAMIMURA2, Yasushi YAMAZOE1, 3
1Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan, 2Drug Metabolism Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Tokyo, Japan, 3Tohoku University 21st Century, COE Program "Comprehensive Research and Education Center for Planning of Drug Development and Clinical Evaluation", Sendai, Japan, 4Department of Environmental Health Science, Tohoku Pharmaceutical University, Sendai, Japan
DRUG METABOLISM AND PHARMACOKINETICS 22 (4) 287-298, 2007.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
In Vitro Study of 6-mercaptopurine Oxidation Catalysed by Aldehyde Oxidase and Xanthine Oxidase
Mohammad-Reza RASHIDI1, Christine BEEDHAM2, John S. SMITH3, Soodabeh DAVARAN4
1Drug Applied Research Center, Research and Development Complex, Tabriz University of Medical Sciences, Tabriz, Iran, 2Department of Clinical Sciences, 3Department of Pharmaceutical Chemistry, School of Life Sciences, University of Bradford, Richmond Road, Bradford, West Yorkshire, UK, 4Pharmaceutical Nonotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
DRUG METABOLISM AND PHARMACOKINETICS 22 (4) 299-306, 2007.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Efflux Transport of N-monodesethylamiodarone by the Human Intestinal Cell-Line Caco-2 Cells
Emi KIMOTO1, Satoru SEKI1, Shirou ITAGAKI1, Maya MATSUURA1, Masaki KOBAYASHI1, Takeshi HIRANO1, Yoshikazu GOTO2, Koji TADANO2, Ken ISEKI1
1Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan, 2Department of Pharmacy, Sapporo City General Hospital, Sapporo, Japan
DRUG METABOLISM AND PHARMACOKINETICS 22 (4) 307-312, 2007.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Decreased Intestinal CYP3A and P-glycoprotein Activities in Rats with Adjuvant Arthritis
Satoshi UNO1, 2, Atsushi KAWASE1, Akiko TSUJI1, Tadatoshi TANINO1, Masahiro IWAKI1
1Department of Pharmacy, Kinki University, Osaka, Japan, 2Pharmaceutical Research, Pharmaceuticals R&D Division, Alfresa Pharma Corporation, Osaka, Japan
DRUG METABOLISM AND PHARMACOKINETICS 22 (4) 313-321, 2007.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
Novel SNPs in Cytochrome P450 Oxidoreductase
Steven N. HART, Ye LI, Kaori NAKAMOTO, Chris WESSELMAN, Xiao-bo ZHONG
Department of Pharmacology, Toxicology, and Therapeutics, The University of Kansas Medical Center, Kansas, USA
DRUG METABOLISM AND PHARMACOKINETICS 22 (4) 322-326, 2007.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。