ENDOCRINE JOURNAL 57巻 suppl.2-2号

前の号 次の号

発行元: 日本内分泌学会

ISSN: 0918-8959

ISSN（オンライン）: 1348-4540

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P2-3-2 Effects of citrus auraptene on glucose and lipid metabolism in obese diabetic KK-Ay mice

Mari Senda(1), Kana Ohyama(1), Kayo Kuroyanagi(1), Kanako Nishimura(1), Tsuyoshi Goto(1), Masamichi Yano(2), Takao Sasaki(3), Nobuyuki Takahashi(1), Teruo Kawada(1)
(1)Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, (2)Department of Citriculture, National Institute of Fruit Tree Science, Ministry of Agriculture, Forestry and Fisheries, (3)ARKRAY Inc
ENDOCRINE JOURNAL 57 (suppl.2-2) S411-S411, 2010.

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P2-3-3 Role of plasma adiponectin in preventing the incidence of cerebral lesions of a rat spontaneous stroke model without the metabolic syndrome

Hiroshi Sakaue(1), Masaki Tabuchi(2), Kana Ooshima(2), Hideaki Higashino(2)
(1)Department of Nutrition and Metabolism, Institute of Health Biosciences, the University of Tokushima, (2)Graduate School, 2 Department of Pharmacology, Kinki University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S411-S411, 2010.

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P2-3-4 Anti-obesity and anti-diabetic effects of acacia polyphenol in obese diabetic KKAy mice fed high-fat diet

Nobutomo Ikarashi, Takahiro Toda, Kiyomi Ito, Wataru Ochiai, Kiyoshi Sugiyama
Department of Clinical Pharmacokinetics, Hoshi University
ENDOCRINE JOURNAL 57 (suppl.2-2) S411-S411, 2010.

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P2-3-5 Pioglitazone-induced proliferation of mature adipocytes

Takayuki Hanamoto, Kazuo Kajita, Takahide Ikeda, Ichiro Mori, Kei Fujioka, Hideyuki Okada, Takatoshi Fujikake, Masahiro Yamauchi, Yoshihiro Uno, Hiroyuki Morita, Tatsuo Ishizuka
Department of General Internal Medicine, Gifu University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S411-S411, 2010.

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P2-3-6 Quercetin inhibits adipogenesis in primary cultured orbital fibroblasts from patients of Graves' ophthalmopathy

Hyun Jung Lee(1), Jin Sook Yoon(2), Eun Jig Lee(3)
(1)Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, (2)Department of Ophthalmology, Yonsei University College of Medicine, (3)Department of Endocrinology, Yonsei University College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S412-S412, 2010.

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P2-3-7 Adipocyte differentiation of human induced pluripotent stem cells

Michio Noguchi, Kiminori Hosoda, Eisaku Mori, Kazuhiro Nakao, Daisuke Taura, Maskatsu Sone, Yuji Yamamoto, Junji Fujikura, Ken Ebihara, Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S412-S412, 2010.

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P2-4-1 Pattern of body composition in young adults Nigerians

Sandra O.Iwuala, Olufemi A Fasanmade
Department of Internal Medicine, Lagos University Teaching Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S412-S412, 2010.

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P2-4-2 Interactive life style intervention program by healthy life coordinator monitoring internet-based daily physical data in Japanese male patients with metabolic syndrome

Keiko Suyama(1), Tomoaki Tanaka(1), Takashi Terano(2), Shinya Kuno(3), Kotaro Yokote(1), Ichiro Tatsuno(1)
(1)Department of Clinical Cell Biology and Medicine, Chiba University Graduate School of Medicine, (2)Department of Internal Medicine, Chiba Aoba Municipal Hospital, (3)Graduate School of Comprehensive Human Sciences, University of Tsukuba
ENDOCRINE JOURNAL 57 (suppl.2-2) S412-S412, 2010.

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P2-4-3 Impact of abdominal obesity on the development of risk components of metabolic syndrome in middle-aged Japanese workers:MONK Study

Kenji Moriyama(1), (2), Yuiko Kago(1), Hiroyuki Yamamoto(1), Nozomi Kobayashi(3), Takashi Miyawaki(2), (3), Midori Ida(3), (4), Masakazu Hirata(3), (4), Yutaka Takemoto(3), Nobuo Saito(3), Kazuwa Nakao(4)
(1)Mukogawa Women's University, (2)NTT WEST, Health Administration Center of Kansai, (3)NTT WEST Kyoto Hospital, Health Administration Center, (4)Kyoto University, Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S413-S413, 2010.

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P2-4-4 Evaluation of whole-abdominal fat volume by 700-slice CT scanning and comparison with the umbilical fat area anthropometric indices

Kentarou Furukawa(1), Takuyuki Katabami(1), Yasuo Nakajima(2), Yasushi Tanaka(1)
(1)Division of Metabolism and Endocrinology, St.Marianna University School of Medicine, (2)Department of Radiology, St.Marianna University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S413-S413, 2010.

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P2-4-5 The risk of obesity in university students:Relationship between onset of lifestyle-related disease in alumni and their body weight when they were university students

Mayumi Yamamoto(1), (2), (3), Mika Tanaka(1), (4), Tadahiro Sado(1), Katsuji Shimizu(1), (5)
(1)Health Administration Center, Gifu University, (2)Division of Medical Informatics, Gifu Univerisyt United Graduate School of Drug Discovery and Medical Informatic Sciences, (3)The Department of Diabetes and Endocrinology, Gifu University Graduate School of Medicine, (4)The Department of Psychopathology, Gifu University Graduate School of Medicine, (5)The Department of Orthpaedic Surgery, Gifu University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S413-S413, 2010.

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P2-4-6 Impact of waist circumference measurement variation on the diagnosis of metabolic syndrome

Michelle V.Lemoncito, Elizabeth P.Pacheco, Mary Anne L.Abrahan, Gabriel V.Jasul, Iris Thiele I.Tan, Cherrie Mae Sison
Section of Endocrinology & Metabolism, University of the Philippines-Philippine General Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S413-S413, 2010.

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P2-4-7 Anthropometric and lifestyle indices of healthcare professionals in a Nigerian urban teaching hospital

Augustine E.Ohwovoriole, Ofem Enang, Olufemi A Fasanmade
Department of Medicine, College of Medicine, University of Lagos
ENDOCRINE JOURNAL 57 (suppl.2-2) S414-S414, 2010.

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P2-4-8 The assessment of visceral fat accumulation by dual bioelectrical impedance analysis in weight reduction therapy

Midori Ida(1), Masakazu Hirata(1), Eisaku Mori(1), Shinji Odori(1), Eri Kondo(1), Ken Ebihara(1), Hiroaki Masuzaki(1), Hosoda Kiminori(1), Hidetake Ooshima(2), Toshikazu Shiga(2), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, the Graduate School of Kyoto University, (2)Omron Healthcare Company
ENDOCRINE JOURNAL 57 (suppl.2-2) S414-S414, 2010.

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P2-5-1 Effect of obesity and gender difference in 24-hour variation in human peripheral blood mononuclear cells circadian rhythm-related genes

Kazunobu Tahira(1), Takahiro Ueno(1), Noboru Fukuda(1), Akiko Tsunemi(1), Taro Matumoto(1), Shiro Matumoto(1), Chinami Nagura(1), Masayoshi Soma(1), Koichi Matsumoto(1), Shigeki Shimba(2), Yoshiaki Matsumoto(3)
(1)Department of Medicine, Division of Nephrology, Hypertension and Endocrinology, Nihon University School of Medicine, (2)Department of Health Science, College of Pharmacy, Nihon University, (3)Department of Clinical Pharmacokinetics, College of Pharmacy, Nihon University
ENDOCRINE JOURNAL 57 (suppl.2-2) S414-S414, 2010.

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P2-5-2 Association of gene polymorphism of the fat-mass and obesity-associated gene with insulin resistance in Japanese

Izumi Shimaoka(1), Kei Kamide(1), Tomohiro Katsuya(2), Ryosuke Oguro(1), Ada Congrains(1), Ken Sugimoto(1), Hiroshi Akasaka(3), Shigeyuki Saitoh(3), Mitsuru Ohishi(1), Kazuaki Shimamoto(3), Hiromi Rakugi(1)
(1)Department of Geriatric Medicine, Osaka University Graduate School of Medicine, (2)Department of Clinical Gene Therapy, Graduate School of Medicine, Osaka University, (3)Second Department of Internal Medicine, Sapporo Medical University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S414-S415, 2010.

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P2-5-3 The inverse relationship between free testosterone and insulin resistance in Japanese men with metabolic syndrome

Hajime Ueshiba, Saburo Nakano, Tomoko Matsumoto, Gen Yoshino
Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Toho University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S415-S415, 2010.

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P2-5-4 Effects of natural dietary antioxidants on insulin secretion in metabolic syndrome

Antonio Mancini(1), Giuseppe E.Martorana(2), Vincenzo Di Donna(1), Roberto Soave(2), Erika Leone(1), Marinella Magini(2), Sebastiano Raimondo(1), Roberto Festa(3), Elisabetta Meucci(2), Giacinto A.D.Miggiano(2), Alfredo Pontecorvi(1)
(1)Department of Internal Medicine, Catholic University of the Sacred Heart, (2)Department of Laboratory Medicine, Catholic Univeristy of the Sacred Heart, (3)Institute of Clinical Pathology, Polytechnic University of Marche
ENDOCRINE JOURNAL 57 (suppl.2-2) S415-S415, 2010.

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P2-5-5 Visfatin concentration in subjects with obesity

Roman Junik(1), Anna Kaminska(1), Ewa Kopczynska(2), Malgorzata Zmudzinska(1), Agata Bronisz(1), Maciej Bielinski(3), Alina Borkowska(3), Danuta Zalewska-Rydzkowska(1)
(1)Dept.of Endocrinology and Diabetology, Nicolaus Copernicus University in Torun, (2)Dept.of Patobiochemistry and Clinical Chemistry, Nicolaus Copernicus University in Torun, (3)Dept.of Neuropsychology, Nicolaus Copernicus University in Torun
ENDOCRINE JOURNAL 57 (suppl.2-2) S415-S415, 2010.

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P2-5-6 Visfatin, adiponectin, leptin and macrophage migration inhibitory factor(MIF)in severe obese women with normal and impaired glucose tolerance

Mirjana S Sumarac-Dumanovic(1), Dragon Micic(1), Vladimir Trajkovic(2), Darko Stevanovic(3), Danica Stamenkovic-Pejkovic(1), Jagoda Jorga(4), Goran Cvijovic(1), Danka Jeremic(1), Aleksanadra Kednereski(1), Svetlana Zoric(1)
(1)Institute of Endocrinology, Diabetes and Diseases of Metabolism, School of Medicine Belgrade, (2)School of Medicine, Institute of Immunology, (3)School of Medicine, Institute of Physiology, (4)School of Medicine, Institute of Eating Disordes
ENDOCRINE JOURNAL 57 (suppl.2-2) S415-S416, 2010.

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P2-5-7 Relationship of anthropometric indices and blood pressure levels in rural Borno, northeastern Nigeria

Bilkisu M.Mubi, Ibrahim D.Gezawa, Shuaib J.Yahaya, Ibrahim Halliru
University of Maiduguri Teaching Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S416-S416, 2010.

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P2-5-8 Establishing abdominal height cut-offs and its association to conventional indices of obesity among Arab children and adolescents

Majed Alokail(1), Nasser Al-Daghri(1), Omar Al-Attas(1), Khalid Al-Rubeaan(2), Shaun Sabico(1), Sudhesh Kumar(3)
(1)Biochemistry Department, King Saud University, (2)University Diabetes Center, King Saud University, (3)Diabetes & Metabolism Unit, University of Warwick
ENDOCRINE JOURNAL 57 (suppl.2-2) S416-S416, 2010.

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P2-6-1 Leptin modulates brain activity associated with feeding behavior in patients with lipodystrophy

Daisuke Aotani(1), Ken Ebihara(1), (2), Nobukatsu Sawamoto(3), Toru Kusakabe(1), Yuji Yamamoto(1), Licht Miyamoto(1), Sachiko Yamamoto-Kataoka(1), Takeru Sakai(1), Junji Fujikura(1), Kiminori Hosoda(1), (2), Hidenao Fukuyama(3), Kazuwa Nakao(1), (2)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Translational Research Center, Kyoto University Hospital, (3)Human Brain Research Center, Graduate School of Medicine, Kyoto University
ENDOCRINE JOURNAL 57 (suppl.2-2) S416-S416, 2010.

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P2-6-2 Leptin improved glycemic control with a dramatic reduction of visceral fat in a patient with Dunnigan variety of familial partial lipodystrophy

Hitomi Iogawa(1), Ken Ebihara(1), (2), Toru Kusakabe(1), Yuji Yamamoto(1), Megumi Aizawa-Abe(1), (2), Daisuke Aotani(1), Sachiko Yamamoto-Kataoka(1), Takeru Sakai(1), Kiminori Hosoda(1), (2), Kazuwa Nakao(1), (2)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Translational Research Center, Kyoto University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S416-S417, 2010.

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P2-6-3 Leptin modulates the antiangiogenic effect of thalidomide and bevacizumab on murine endothelial HECa 10 cell line in vitro

Gabriela Melen-Mucha(1), Joanna Polowinczak-Przybylek(2)
(1)Department of Immunoendocrinology, Medical University of Lodz, (2)Department of the Proliferative Diseases, Regional Oncological Centre in Lodz
ENDOCRINE JOURNAL 57 (suppl.2-2) S417-S417, 2010.

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P2-6-4 Evaluation of nitric oxide synthesis in morbidly obese patients

Adriana Florinela Catoi Galea(1), Alina Parvu(1), Cornel Catoi(2), Adriana Muresan(1), Romeo Florin Galea(1)
(1)Department of Physiology, University of Medicine and Pharmacy Cluj Napoca Romania, (2)University of Agricultural Sciences and Veterinary Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S417-S417, 2010.

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P2-6-5 Effect of adrenomedullin on lipolysis and adipogenesis of 3T3-L1 adipocytes

Hiroshi Arai(1), (2), Takuo Nambu(1), Hiroyuki Ariyasu(1), Yudai Takeuchi(1), Eri Kondo(1), Go Yamada(1), Toshihito Fujii(1), Masako Miura(1), Naotetsu Kanamoto(1), Akihiro Yasoda(1), Masakatsu Sone(1), Naohisa Tamura(1), Ken Ebihara(1), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Kyoto Institute of Technology
ENDOCRINE JOURNAL 57 (suppl.2-2) S417-S417, 2010.

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P2-6-6 Hepatic steatosis on chronic treatment with antidiabetic thiazolidinediones in leptin-unresponsive mice is defined by basal expression of peroxisome proliferators-activated receptor γ in liver and its direct effects upon adipose tissue

Tetsuya Kakuma, Junya Oribe, Miwa Haranaka, Kenjirou Okamoto, Masataka Seike, Hironobu Yoshimatsu
Department of Internal Medicine 1, Faculty of Medicine, Oita University
ENDOCRINE JOURNAL 57 (suppl.2-2) S417-S418, 2010.

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P2-6-7 Lipogenesis and lipolysis enzymes are involved in regulatory action of zinc-α2-glycoprotein in obese mice and 3T3-L1 preadipocytes

Feng Ying Gong, Sao Jun Zhang, Hui Hua Ding, Jie Ying Deng, Hui Juan Zhu, hui Pan, Lin Jie Wang, Nai Shi Li, Yi Fan Shi
Department of Endocrinology, Key Laboratory of Endocrinology of Ministry of Health, Peking Union Medical College Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S418-S418, 2010.

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P2-6-8 Effects of adipokines on gene expression of lipid metabolism regulatory enzymes and its possible mechanism in human HepG2 cells

Feng Ying Gong, Jie ying Deng, Hui juan Zhu, Hui Pan, Yi fan Shi
Department of Endocrinology, Key Laboratory of Endocrinology of Ministry of Health, Peking Union Medical College Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S418-S418, 2010.

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P2-7-1 Stretch-induced activation of Rho/Rho-kinase pathway as a determinant of malignant phenotype of adipose tissue in diet-induced obesity

Yoshikazu Hara(1), Shu Wakino(1), Yoshiyuki Tanabe(2), Maki Saito(2), Hirobumi Tokuyama(1), Naoki Washida(1), Kyoko Yoshioka(1), Koichiro Homma(1), Kazuhiro Hasegawa(1), Hitoshi Minakuchi(1), Keiko Sueyasu(1), Koichi Hayashi(1), Koichi Nakayama(2), Hiroshi Itoh(1)
(1)Department of Internal Medicine, School of Medicine, Keio University, (2)Department of Molecular and Cellular Pharmacology, Iwate Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S418-S418, 2010.

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P2-7-2 Genetic and pharmacological inhibition of Rho-associated kinase II enhances adipogenesis

Kiminori Hosoda(1), Michio Noguchi(1), Junji Fujikura(1), Muneya Fujimoto(1), Hiroshi Iwakura(1), Tsutomu Tomita(1), Takako Yonemoto(1), Naoki Arai(1), Masakazu Hirata(1), Ken Ebihara(1), Hiroaki Masuzaki(1), Hiroshi Itoh(1), Shuh Narumiya(2), Kazuwa Nakao(1)
(1)Dept Endocrinol and Metabolism, Kyoto University Graduate School of Medicine, (2)Department of Pharmacology, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S418-S419, 2010.

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P2-7-3 The soy isoflavone, genistein, inhibits 11β-hyroxysteroid dehydrogenase type 1 activity in rodent adipocytes

Tagawa Noriko, Sayaka Kubota, Yuko Yamaguchi, Midori Wakabayashi, Daisuke Kiyonaga, Yoshiharu Kobayashi
Department of Medical Biochemistry, Kobe Pharmaceutical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S419-S419, 2010.

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P2-7-4 Role of GPR103b, a new G-protein coupled receptor, in the peripheral regulation of adipogenesis

Huy Ong(1), Mukandila Mulumba(1), Christian Jossart(1), Emmanuel Escher(2), Marc Servant(1), Riccarda Granata(3), Ezio Ghigo(1), (3), Sylvie Marleau(1)
(1)Faculty of Pharmacy, Universite de Montreal, (2)Faculty of Medecine, University of Sherbrooke, (3)Faculty of medecine, university of Turin
ENDOCRINE JOURNAL 57 (suppl.2-2) S419-S419, 2010.

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P2-7-5 Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibition JNK activation

Kanako Nishimura(1), Chieko ando(1), Nobuyuki Takahashi(1), Shizuka Hirai(1), Kanako Nishimura(1), Shan Lin(1), Taku Uemura(1), Tsuyoshi Goto(1), Rina Yu(2), Joji Nakagami(3), Shigeru Murakami(3), Teruo Kawada(1)
(1)Division of Food Science and Biotechnology, Graduate School of Agriculture, (2)Department of Food Science and Nutrition, University of Ulsan, (3)Taisho Pharmaceutical Co., Ltd
ENDOCRINE JOURNAL 57 (suppl.2-2) S419-S419, 2010.

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P2-7-6 Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice

Shiho Fujisaka, Isao Usui, Agussalim Bukhari, Yukiko Kanatani, Satoko Senda, Yu Yamazaki, Hikari Suzuki, Manabu Ishiki, Aminuddin Aminuddin, Masaharu Urakaze, Kazuyuki Tobe
The First Department of Internal Medicine, University of Toyama
ENDOCRINE JOURNAL 57 (suppl.2-2) S419-S420, 2010.

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P2-7-7 Regulation of the 5'flanking region of the mouse chemerin gene in MIN6 cell line

Elizabeth-Henny Herningtyas(1), Hiromi Shibahara(2), Michiko Takahashi(3), Naoki Saito(2), Eri Honda(2), Haruka Wada(2), Anastasia Evi Handayaningsih(3), Genzo Iguchi(3), Keiji Iida(4), Kazuo Chihara(4), Yutaka Takahashi(3), Yasuhiko Okimura(2)
(1)Department of Clinical Pathology, Faculty of Medicine, Gadjah Mada University, (2)Department of Biophysics, Kobe University Graduate School of Health Science, (3)Diabetes, Metabolism and Endocrinology Division, Department of Internal Medicine, Graduate School of Medicine, Kobe University, (4)Department of Medicine, Hyogo Prefectural Kakogawa Hospital, (5)College of Nursing Art and Science, University of Hyogo
ENDOCRINE JOURNAL 57 (suppl.2-2) S420-S420, 2010.

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P2-7-8 Effect of gender-specific adult bovine serum on FAT/CD36 during transdifferentiation of myogenic satellite cells

Prati Bajracharya(1), Dong-Mok Lee(2), Eun Ju Lee(2), Inho Choi(1), (2)
(1)Department of Biotechnology, Yeungnam University, (2)School of Biotechnology, Yeungnam University
ENDOCRINE JOURNAL 57 (suppl.2-2) S420-S420, 2010.

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P2-8-1 Decreased gene expression of a G protein-coupled fatty acid receptor GPR40 in pancreatic islets of Koletsky rats

Tsutomu Tomita, Kiminori Hosoda, Shinji Odori, Junji Fujikura, Hiroshi Iwakura, Michio Noguchi, Eisaku Mori, Masaki Naito, Toru Kusakabe, Ken Ebihara, Hiroaki Masuzaki, Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S420-S420, 2010.

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P2-8-2 Branched-chain amino acid regulates the accumulation of tissue triglycerides in diet-induced obese through the tissue-specific activation of lipid oxidation in diet-induced obese mice

Mie Arakawa, Takayuki Masaki, Junko Nishimura, Masataka Seike, Hironobu Yoshimatsu
The First Department of Internal Medicine, University of Oita
ENDOCRINE JOURNAL 57 (suppl.2-2) S420-S420, 2010.

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P2-8-3 What is syndromes of inappropriate insulin secretion(SITS)?

Yu-ichi Shinoda(1), (2), Ikuo Inoue(3), Sei-ichi Goto(4), Shigehiro Katayama(3)
(1)Department of Rehabilitation, Kamagaya General hospital, (2)Department of Biochemistry, Saitama Medical University, (3)Division of Diabetes and Endocrinology, Saitama Medical University, (4)Department of Internal Medicine, Meikai University School of Dentistry
ENDOCRINE JOURNAL 57 (suppl.2-2) S421-S421, 2010.

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P2-8-4 A severe case of acanthosis nigricans with review

Juliana Austin
Miller Children's Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S421-S421, 2010.

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P2-8-5 The therapeutic possibility of leptin:The new remedy of fatty liver

Sachiko Kataoka Y.(1), Ken Ebihara(2), megumi A.Abe(2), Toru Kusakabe(1), Yuji Yamamoto(1), Licht Miyamoto(1), Daisuke Aotani(1), Takeru Sakai(1), Kiminori Hosoda(1), (2), Kazuwa Nakao(1), (2)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Translational Research Center, Kyoto University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S421-S421, 2010.

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P2-8-6 Adipose tissue regulates hepatic and renal expression of the genes responsible for fatty acid biosynthesis in different manners:A study in lipodystrophic mice

Mingming Zhao, Yuhao Li, Xianglu Rong, Ken Ebihara, Toru Kusakabe, Takashige Kuwabara, Kiyoshi Mori, Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S421-S421, 2010.

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P2-8-7 Pilot study to confirm that ovine fat and liver can be distinguished by spectroscopic tissue response on a Medipix-All-Resolution-System-CT(MARS-CT).

Nicola J.A.Scott(1), James M.Carr(3), Michael J.Clark(3), Nicholas J.Cook(4), Nigel G.Anderson(2), Alexandra P.Butler(2), Philip H.Butler(3), (6), Anthony P Butler(2), (5), (6), Kyra B.Berg(1)
(1)Department of Medicine, University of Otago-Christchurch, (2)Department of Radiology, University of Otago, (3)Physics and Astronomy, University of Canterbury, (4)Department of Medical Physics, Canterbury District Health Board, (5)Electrical and Computer Engineering, University of Canterbury, (6)European Organization for Nuclear Research
ENDOCRINE JOURNAL 57 (suppl.2-2) S421-S422, 2010.

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P2-8-8 Relationships between non-alcoholic fatty liver disease and left ventricle index in obese Turkish children

Beray Selver(2), Enver Simsek(1), Ugur Kocabas(2), Yildiz Dallar(1)
(1)Ankara Research and Training Hospital Departments of Pediatric Endocrinology, (2)Cardiology
ENDOCRINE JOURNAL 57 (suppl.2-2) S422-S422, 2010.

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P2-9-1 A new organotypic culture of adipose tissue fragments maintains viable mature adipocytes for a long term, together with development of immature adipocytes and mesenchymal stem cell-like cells

Kazuyoshi Uchihashi(1), Shigehisa Aoki(1), Aki Matsunobu(1), Fumio Yamasaki(2), Eisuke Koike(3), Nobuhisa Yonemitsu(4), Sadayuki Funatsumaru(6), Hajime Sugihara(5), Shuji Toda(1)
(1)Department of Pathology & Microbiology, Faculty of Medicine, Saga University, (2)Pathology Department, Saga University Hospital, (3)Koike Hospital, (4)Sasebo Chuo Hospital, (5)International University of Health and Welfare, The School of Rehabilitation Sciences, (6)Prefectural Meat Inspection Office
ENDOCRINE JOURNAL 57 (suppl.2-2) S422-S422, 2010.

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P2-9-2 Identification of tumor suppressor candidate 5(TUSC5/BEC1), a novel PPAR target; its expression and role in the adipocyte differentiation

Takafumi Mayama, Tomoaki Tanaka, Kotaro Yokote, Ichiro Tatsuno
Department of Clinical Cell Biology, Chiba University Graduate School of Medicine, Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Chiba University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S422-S422, 2010.

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P2-9-3 Genome-wide ChIP-seq profiling of PPARγ/RXRα binding sites in adipocytes revealed PPAR response elements in the intron 1 of AdipoR2

Hironori Waki(1), Toshimasa Yamauchi(1), Ken-ichi Wakabayashi(2), Jing Yu(1), Tatsuhiko Kodama(3), Hiroyuki Aburatani(2), Juro Sakai(4), Takashi Kadowaki(1)
(1)Department of Metabolic Diseases, Graduate School of Medicine, the University of Tokyo, (2)Genome Science Division, (3)Vascular System Division, (4)Metabolism and Endocrinology Division, (5)Laboratory of Systems Biology and Medicine, Research Center for Advanced Science and Technology, the University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S422-S423, 2010.

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P2-9-4 Roles of Wilms' tumor 1-associating protein(WTAP)in development of obesity and diabetes

Masatoshi Kobayashi(1), Mitsuru Ohsugi(1), Takayoshi Sasako(1), Naoki Kobayashi(1), Miho Suzuki(1), Kazuma Kaneko(1), Motoharu Awazawa(1), Yukiko Okazaki(1), Kohjiro Ueki(1), Keiko Horiuchi(2), Takao Hamakubo(2), Tatsuhiko Kodama(2), Takashi Kadowaki(1)
(1)Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, University of Tokyo, (2)Research Center for Advanced Science and Technology, University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S423-S423, 2010.

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P2-9-5 The effect of SIRT1 activator on inflammation and oxidative stress in white adipose tissue of high fat-fed mice

Yukiko Kanatani(1), Isao Usui(1), Shiho Fujisaka(1), Yuji Matsuya(2), Satoko Senda(1), Akiko Takikawa(1), Aminuddin Aminuddin(1), Manabu Ishiki(1), Masaharu Urakaze(1), Kazuyuki Tobe(1)
(1)First Department of Internal Medicine, University of Toyama, (2)Graduate School of Medicine and Pharmaceutical Science
ENDOCRINE JOURNAL 57 (suppl.2-2) S423-S423, 2010.

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P2-9-6 c-Ski transgenic mice are resistant to diet-induced obesity

Marianne Diaz(1), (2), Nick Martel(1), (2), Steve Myers(1), Rebecca L.Fitzsimmons(1), Michael A.Pearen(1), George E.O.Muscat(1), Gary M.Leong(1), (2)
(1)Institute For Molecular Bioscience, University of Queensland, (2)Department of Paediatric Endocrinology and Diabetes, Mater Children's Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S423-S423, 2010.

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P2-9-7 Profiling of nuclear hormone receptor mRNA expression in peripheral mononuclear blood cells from pre-pubertal children with obesity and healthy weight

Shaffinaz Abd Rahman(1), Nick Martel(1), Natalie Eriksson(1), George E.O.Muscat(1), Gary M.Leong(1), (2)
(1)Institute for Molecular Bioscience, The University of Queensland, (2)Department of Paediatric Endocrinology and Diabetes, Mater Children's Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S423-S424, 2010.

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P2-9-8 Serum Fibroblast Growth Factor 21 in human obesity:Regulation by hyperinsulinemia and relationship with glucose and lipid oxidation

Marek Straczkowski, Monika Karczewska-Kupczewska, Agnieszka Adamska, Agnieszka Nikolajuk, Agnieszka Lebkowska, Elzbieta Otziomek, Maria Gorska, Irina Kowalska
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok
ENDOCRINE JOURNAL 57 (suppl.2-2) S424-S424, 2010.

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P2-10-1 Contribution of(pro)renin receptor to the development of insulin resistance in obese hypertensive rats

Tadashi Kamayachi(1), Atsuhiro Ichihara(2), Mariyo Sakoda(1), Asako Kurauchi-Mito(1), Tatsuya Narita(1), Kenichiro Kinouchi(1), Kanako Bokuda(1), Hiroo Kumagai(3), Hiroshi Itoh(1)
(1)Department of Internal Medicine, Keio University School of Medicine, (2)Endocrinology and Anti-Aging Medicine, Keio University School of Medicine, (3)Department of Nephrology, National Defense Medical College
ENDOCRINE JOURNAL 57 (suppl.2-2) S424-S424, 2010.

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P2-10-2 Effects of candesartan on expressions of PPARgamma; in liver and adipose tissue of high-fat diet-fed rats

Jingtao Dou, Wenhua Yan, Changyu Pan, Kang Chen, Baoan Wang, Fangling Ma
Department of Endocrinology, PLA General
ENDOCRINE JOURNAL 57 (suppl.2-2) S424-S424, 2010.

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P2-10-3 Effects of the Renin-angiotensin system blockade on glomerular filtration rate(GFR)in diabetic patients with hypertension

Yasuhiko Hara, Ayako Ochi, Naoko Kukida, Hitoo Tokunaga, Yasuhiro Inoue, Osamu Ebisui, Ikki Shimizu
The Depatrment of Diabetes and Endocrinology, Ehime Prefectural Central Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S424-S425, 2010.

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P2-10-4 Nutritional status but not iron determines serum neutrophil gelatinase-associated lipocalin(Ngal)levels in maintenance hemodialysis patients

Hirotaka Imamaki(1), Kiyoshi Mori(1), Masashi Mukoyama(1), Masato Kasahara(1), Hideki Yokoi(1), Takashige Kuwabara(1), Takashi Kuwahara(2), Masugi Satou(3), Kimihiko Nakatani(4), Yoshihiko Saito(4), Yoshihisa Ogawa(1), Tokomo Kawanishi(1), Naohisa Tomosugi(5), Akira Sugawara(6), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Graduate School of Medicine, Kyoto University, (2)Department of Nephrology, Saiseikai Nakatsu Hospital, (3)Misugikai Satou Hospital, (4)First Department of Internal Medicine, Nara Medical University, (5)Proteomics Research Unit, Medical Research Institute, Kanazawa Medical University, (6)Department of Nephrology, Kyoto Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S425-S425, 2010.

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P2-10-5 Effects of brown and white rice diet on visceral adiposity and endothelial function:The BRAVO study

Juri Hasegawa(1), Moritake Higa(1), Hideaki Tanaka(2), Michio Shimabukuro(3), Hiroaki Masuzaki(3)
(1)Diabetes and Lifestyle-related disease Center, Tomishiro Central Hospital, (2)Tanaka Clinic, (3)Second Department of internal Medicine, University of the Ryukyus
ENDOCRINE JOURNAL 57 (suppl.2-2) S425-S425, 2010.

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P2-10-6 Effects of 6-month treatment with losartan/hydrochlorothiazide(HCTZ), when changed from ARBs of usual dosage, on various metabolic parameters including blood pressures and high molecular weight(HMW)-adiponectin levels in Japanese male hypertensive subjects

Hiroshi Hirose, Hiroshi Kawabe, Ikuo Saito
Health Center, Keio University, Department of Internal Medicine, School of Medicine, Keio University
ENDOCRINE JOURNAL 57 (suppl.2-2) S425-S425, 2010.

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P2-10-7 Weight gain is associated with a decrease in eGFR in middle-aged dwelling people

Shozo Yano(1), Toru Nabika(2), Toshitsugu Sugimoto(1)
(1)Department of Internal Medicine 1, Shimane University Faculty of Medicine, (2)Department of Molecular Pathology, Shimane University Faculty of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S425-S426, 2010.

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P2-10-8 The effects of insulin resistance and adipocytekines on plasma levels of B-type natriuretic peptide in a general urban Japanese population

Ichiro Kishimoto(1), Takako Sugisawa(1), Yoshihiro Kokubo(2), Hisashi Makino(1), Yoshihiro Miyamoto(1), Tomonori Okamura(2), Yasunao Yoshimasa(1)
(1)Department of Atherosclerosis and Diabetes, National Cardiovascular Center, (2)Department of Preventive Cardiology, National Cardiovascular Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S426-S426, 2010.

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P2-11-1 Hormonal regulation of acetyl-Co carboxylase isoenzyme gene transcription

Li-Feng Zhao(1), Yasumasa Iwasaki(2), Mitsuru Nishiyama(1), Takafumi Taguchi(1), Makoto Tsugita(1), Mizuho Okazaki(1), Shuichi Nakayama(1), Yoshio Terada(1)
(1)Department of Endocrinology, Metabolism, and Nephrology, Kochi Medical School, Kochi University, (2)Health Care Center, Kochi University
ENDOCRINE JOURNAL 57 (suppl.2-2) S426-S426, 2010.

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P2-11-2 Hypothalamic neuronal histamine signalling in the oestrogen deficiency-induced obesity

Koro Gotoh(1), Takayuki Masaki(1), Seiichi Chiba(1), Keiko Higuchi(1), Tetsuya Kakuma(1), Hiroyuki Shimizu(2), Masatomo Mori(2), Toshiie Sakata(1), Hironobu Yoshimatsu(1)
(1)The First Departmen of Internal Medicine, Oita University, (2)Department of Medicine and Molecular Science, Gunma University
ENDOCRINE JOURNAL 57 (suppl.2-2) S426-S426, 2010.

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P2-11-3 C-type natriuretic peptide as a new regulator of energy expenditure

Megumi Inuzuka(1), Naohisa Tamura(1), Goro Katsuura(1), Nobuko Yamada(1), Kosaku Ohinata(2), Masakatsu Sone(1), Yasutomo Fukunaga(1), Daisuke Taura(1), Takuhiro Sonoyama(1), Katsutoshi Kojima(1), Kyoko Honda(1), Akihiro Yasoda(1), Hiroshi Arai(1), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University
ENDOCRINE JOURNAL 57 (suppl.2-2) S426-S427, 2010.

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P2-11-4 Changes of mRNA expressions of neuropeptides and their receptors in the hypothalamus of leptin transgenic skinny mice

Yukari Ochi, Goro Katsuura, Nobuko Yamada, Ken Ebihara, Kiminori Hosoda, Kazuwa Nakao
Division of Endocrinology and Metabolism, Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S427-S427, 2010.

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P2-11-5 High fat diet and nicotine administration in combination augments endocannabinoid CB1 receptor expression in hypothalamic nuclei in mice

Tomohiro Tanaka(1), Hiroaki Masuzaki(1), Shintaro Yasue(1), Takako Ishii-Yonemoto(1), Naoki Arai(1), Hideki Chusho(1), Tsutomu Tomita(1), Junji Fujikura(1), Ken Ebihara(1), Yasuhiko Minokoshi(2), Kiminori Hosoda(1), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Developmental Physiology, National Institute for Physiological Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S427-S427, 2010.

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P2-11-6 Regulation of hypothalamic Fto expression by glucose in mice

Nicole J.Poritsanos(1), Pei San Lew(1), Davie Wong(1), Julia Fischer(2), Ulrich Ruther(2), Tooru M.Mizuno(1)
(1)Department of Physiology, University of Manitoba, (2)Institute for Animal Developmental and Molecular Biology, Heinrich Heine University
ENDOCRINE JOURNAL 57 (suppl.2-2) S427-S428, 2010.

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P2-11-7 Molecular forms and the dynamics of n-decanoyl ghrelin, another acyl-form of active ghrelin, in human plasma

Junko Yoh(1), (2), Yoshihiro Nishi(1), Hiroshi Hossoda(3), Munetsugu Hara(4), Toyojiro Matsuishi(4), Kenji Kangawa(3), Jingo Kusukawa(2), Eiichiro Tanaka(1)
(1)Department of Physiology, Kurume University School of Medicine, (2)Dental and Oral Medical Center, Kurume University School of Medicine, (3)Department of Biochemistry, National Cardiovascular Center Research Institute, (4)Department Of Pediatrics, Kurume University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S428-S428, 2010.

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P2-11-8 Involvement of ghrelin in food-anticipatory activity in the activity-based anorexia model

Emil Egecioglu(1), Linda A.W.Verhagen(2), Mieneke C.M.Luijendijk(2), Jacquelien J.G.Hillebrand(4), Mohammad R.Bohlooly-Y(3), Suzanne L.Dickson(1), Roger A.H.Adan(2)
(1)Inst Neuroscience and Physiology, Gotheburg University, (2)Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, (3)AstraZeneca R&D, (4)Rintveld Centre for Eating Disorders, Altrecht Mental Health Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S428-S428, 2010.

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P2-12-1 A case of cholangiocarcinoma in congenital generalized lipodystrophy

Megumi Aizawa-Abe(1), Sachiko Yamamoto-Kataoka(2), Toru Kusakabe(2), Daisuke Aotani(2), Takeru Sakai(2), Takashi Miyazawa(1), Ken Ebihara(1), (2), Kiminori Hosoda(1), (2), Kazuwa Nakao(1), (3)
(1)Department of Experimental Therapeutics, Translational Research Center, Kyoto University Hospital, (2)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (3)Translational Reseach Center, Kyoto University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S428-S428, 2010.

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P2-12-2 Congenital partial lipodystrophy(Kobberling type):A long-term follow-up regarding the efficacy of pioglitazone

Haruka Sasaki(1), (3), Kumiko Ohokubo(2), Kenichi Tomita(3), Kenzo Iino(3), Yuji Tajiri(4), Atsunori Kashiwagi(4), (5), Keiko Uezono(1), Shuzo Kumagai(1)
(1)Institute of Health Science, Kyushu University, (2)Department of Laboratory Medicine, Fukuoka University Hospital, (3)Division of Diabetes and Endocrine Medicine, Chikushi Hospital, Fukuoka University, (4)Department of Diabetes and Endocrine Meicine, Kurume University Hospital, (5)Deparment of Medicine, Shiga University of Medical science
ENDOCRINE JOURNAL 57 (suppl.2-2) S428-S429, 2010.

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P2-12-3 Reduction of body weight by therapy with H2 receptor antagonists

Georgina S.Pudar(1), Branka M.Dapcevic(2), Marina S.Andjelic(1), Petar N.Svorcan(2), Andrijana S.Brankovic(1)
(1)Departement of Endocrinology and Diabetes, University Clinical Center Zvezdara, (2)Departement of Gastroenterology
ENDOCRINE JOURNAL 57 (suppl.2-2) S429-S429, 2010.

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P2-12-4 From stress response to developmental processes in abdominal subcutaneous adipose tissue after bariatric surgery

Simon N.Dankel(1), (2), Dag J.Fadnes(3), Anne-Kristin Stavrum(4), (6), Christine Stansberg(4), (6), Rita Holdhus(4), (6), Tuyen Hoang(1), (2), Vivian L.Veum(1), (2), Bjorn Christensen(7), Villy Vaage(5), Jorn V.Sagen(1), (2), Vidar M.Steen(4), (6), Gunnar Mellgren(1), (2)
(1)Institute of Medicine, University of Bergen, (2)Hormone Laboratory, Haukeland University Hospital, (3)Department of Medicine, Forde Central Hospital, (4)Center for Medical Genetics and Molecular Medicine, MGM, Haukeland University Hospital, (5)Department of Surgery, Forde Central Hospital, (6)Department of Clinical Medicine, University of Bergen, (7)Department of Surgery, Haukeland University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S429-S429, 2010.

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P2-12-5 Non-insulinoma pancreatogenous hypoglycemic syndrome after gastric bypass surgery

Takako Araki, Agustin Busta
Division of Endocrinology and Metabolism, Beth Israel Medical Center, Albert Einstein College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S429-S429, 2010.

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P2-12-6 Synergistic weight loss and diabetes improvement with exenatide administration after laparoscopic gastric banding-case report-

Kyung W.Kim(1), (2), (3), Sung M.Kim(2), Chul Woo Ahn(3), Kyung Rae Kim(3), Eun Jig Lee(3), Bong Soo Cha(3), Hyun Chul Lee(3)
(1)Endocrinology, YonginSeverance Hospital, Yonsei University, (2)Surgery, Yongin Severance Hospital, Yonsei University, (3)Endocrinology, Yonsei University College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S429-S430, 2010.

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P2-12-7 Regression effect on diastolic dysfunction with combination of valsartan and amplodipin in the obese patients

Sefa Sarac(1), Fulden Sarac(2)
(1)Sada Hospital, Department of Cardiology, (2)Ege University Hospital, Department of Internal Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S430-S430, 2010.

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P2-12-8 Metabolic syndrome and insulin resistance in obese patients with obstructive sleep apnea syndrome

Fulden Sarac(1), Ozen Basoglu(2), Sefa Sarac(3), Hatice Uluer(4), Candeger Yilmaz(5)
(1)Department of Internal Medicine, Ege University, (2)Department of Chest Diseases, Ege University, (3)Department of Cardiology, Sada Hospital, (4)Ege University, Department of Biostatistic, (5)Department of Endocrinology and Metabolism, Ege University
ENDOCRINE JOURNAL 57 (suppl.2-2) S430-S430, 2010.

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P2-13-1 Augmented synthesis and secretion of adrenomedullin from adipose tissue in human obesity

Takuo Nambu(1), Hiroshi Arai(1), Shintaro Yasue(1), Hiroaki Masuzaki(1), Naoki Morimoto(2), Takashi Miyawaki(3), Masako Miura(1), Naotetsu Kanamoto(1), Masakatsu Sone(1), Akihiro Yasoda(1), Naohisa Tamura(1), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Plastic and Reconstructive Surgery, Kyoto University Graduate School of Medicine, (3)Health Administration Center, NTT West Kyoto Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S430-S430, 2010.

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P2-13-2 Visceral adiposity strongly predicts delayed hyperinsulinemia in obese and non-obese subjects

Michio Shimabukuro(1), Moritake Higa(2), Hiroaki Masuzaki(1)
(1)Second Department of Internal Medicine University of the Ryukyus, (2)Diabetes and Lifestyle-related disease Center, Tomishiro Chuo Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S430-S430, 2010.

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P2-13-3 Association of urine acidification with visceral obesity and the metabolic syndrome

Tetsuhiro Kitamura(1), Michio Otsuki(1), Hiroshi Saito(2), Mikio Mukai(2), Soji Kasayama(3), Iichiro Shimomura(1), Masafumi Koga2)
(1)Department of Metabolic Medicine, Osaka University Graduate School of Medicine, (2)Department of Internal Medicine, Kinki Central Hospital, (3)Department of Medicine, Nissay Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S431-S431, 2010.

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P2-13-4 Intense low frequency electro-acupuncture increases insulin sensitivity andskeletal muscle protein content of GLUT4 and phosphorylated-Akt in female rats with dihydrotestosterone induced polycystic ovary syndrome

Julia A.Johansson(1), Yi Feng(2), Ruijin Shao(1), Hakan Billig(1), Malin Lonn(3), Elisabet Stener-Victorin(1)
(1)Neuroscience and Physiology, University of Gothenburg, (2)Department of Neurobiology and Integrative Medicine, Shanghai Medical College of Fudan University, (3)Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine, Sahlgrenska Academy, University of Gothenburg
ENDOCRINE JOURNAL 57 (suppl.2-2) S431-S431, 2010.

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P2-13-5 Metabolic characteristics in different phenotypes of polycystic ovary syndrome

Irina Kowalska(1), Monika Karczewska-Kupczewska(1), Agnieszka Adamska(1), Agnieszka Nikolajuk(1), Agnieszka Lebkowska(1), Slawomir Wolczynski(2), Maria Gorska(1), Marek Straczkowski(1)
(1)Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, (2)Department of Reproduction and Gynecological Endocrinology, Medical University of Bialystok
ENDOCRINE JOURNAL 57 (suppl.2-2) S431-S431, 2010.

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P2-13-6 Plasma aldosterone and ratio of aldosterone to active renin in obese and non-obese premenopausal women

Jose Silva-Nunes(1), Conceicao Godinho(2), Isaura Rodrigues(2), Leone Duarte(1), Fernando Malheiro(1)
(1)Endocrinology Department, Curry Cabral Hospital, (2)Clinical Pathology Department, Curry Cabral Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S431-S432, 2010.

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P2-13-7 Prevalence of polycystic ovary syndrome(PCOS)and metabolic syndrome in female to male transsexuals

Antonio Becerra(1), Gilberto Perez-Lopez(2), Maria Jesus Lucio(1), Nuria Asenjo(1), Jose Miguel Rodriguez-Molina(1), (3), Maria Frenzi Rabito(3), Jose Luis Llopis(1)
(1)Gender Unit, Dept Endocrinology, Ramon y Cajal Hospital, University of Alcala, (2)Dept Endocrinology, Ramon y Cajal Hospital, (3)University Autonoma
ENDOCRINE JOURNAL 57 (suppl.2-2) S432-S432, 2010.

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P2-13-8 Subclinical hypothyroidism and its impact on phenotypic expression of PCOS in Indian women

Mohd Ashraf Ganie(1), Iram Rabbani(1), Mudasir Syed(1), A.H.Zaragar(1), Ariachery C.Ammini(2)
(1)Endocrinolgy Sheri-Kashmir Institute of Medical Sciences, (2)AIIMS New Delhi
ENDOCRINE JOURNAL 57 (suppl.2-2) S432-S432, 2010.

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P2-14-1 The effect and safety of ezetimibe, an inhibitor of small intestinal cholesterol transport, in patients with dyslipidemia

Masami Tanaka(1), (2), Hitoshi Ishii(1), Hiroshi Itoh(2)
(1)Department of Endocrinology, Tenri Hospital, (2)Department of Internal Medicine, School of Medicine, Keio University
ENDOCRINE JOURNAL 57 (suppl.2-2) S432-S432, 2010.

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P2-14-2 Pravastatin potentiates increases in serum adiponectin concentration in dyslipidaemic patients receiving thiazolidinedione

Urn Nezu(1), (3), Seishi Tsunoda(2), Hideki Yoshimura(2), Tetsuo Kuwabara(2), Shoken Tomura(2), Yukio Seki(2), Mizuki Kaneshiro(2), Hiroshi Kamiyama(3), Yukina Harada(3), Erina Shigematsu(3), Kazutaka Aoki(3), Tadashi Yamakawa(3), Kenji Ohshige(4), Yasuo Terauchi(1), (4)
(1)Department of Endocrinology and Metabolism, Yokohama City University Graduate School of Medicine, (2)The DOLPHIN investigator, (3)Department of Endocrinology and Metabolism, Yokohama City University Medical Center, (4)Department of Public Health, Yokohama City University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S432-S432, 2010.

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P2-14-3 Enhanced glucagon-like peptide-1(GLP-1)secretion leads to rapid improvement of glucose tolerance and insulin secretion after laparoscopic sleeve gastrectomy(LSG)

Chisato Kusunoki(1), Satoshi Ugi(1), Hiroshi Yamamoto(2), Azusa Kamo(1), Tetsuya Hashimoto(1), Yoshihiko Nishio(1), Kazunori Kasama(3), Toru Tani(2), Atsunori Kashiwagi(1), Hiroshi Maegawa(1)
(1)Departments of Medicine, Shiga University of Medical Science, (2)Departments of Surgery, Shiga University of Medical Science, (3)Yotsuya Medicalcube Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S433-S433, 2010.

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P2-14-4 Clinical feature and effectiveness of intervention in childhood obesity

Masahiro Noda, Keisuke Yoshii, Kiyomi Abe, Yasuhiro Naiki, Reiko Horikawa
Division of Endocrinology and Metabolism, National Center for Child Health and Development
ENDOCRINE JOURNAL 57 (suppl.2-2) S433-S433, 2010.

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P2-14-5 Intraportal administration of DPP-IV inhibitor regulates food intake and insulin secretion through affecting hepatic vagal afferent nerve in rats

Kansuke Fujiwara, Koro Gotoh, Seiichi Chiba, Takayuki Masaki, Isao Katsuragi, Tetsuya Kakuma, Hironobu Yoshimatsu
The First Department of Internal Medicine, University of Oita
ENDOCRINE JOURNAL 57 (suppl.2-2) S433-S433, 2010.

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P2-14-6 An alpha-type-1a receptor antagonist doxazocin decreased insulin resistance and regulates adipocytokines in diet-induced obese mice

Takanobu Shimasaki, Takayuki Masaki, Keiko Higuchi, Hibiki Ota, Koro Gotoh, Seiichi Chiba, Isao Katsuragi, Tetsuya Kakuma, Hironobu Yoshimatsu
Internal Medicine 1 Faculty of Medicine, Oita University
ENDOCRINE JOURNAL 57 (suppl.2-2) S433-S433, 2010.

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P2-14-7 Green tea(-)-epigallocatechin gallate inhibits TNF α-induced PAI-1 production from vascular endothelial cells

Zhongyan Shan, Yanli Cao, Difei Wang, Xin Meng, Jin Zhang
Department of Endocrinology and Metabolism, the First Affiliated Hospital, China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S434-S434, 2010.

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P2-14-8 Green tea(-)-epigallocatechin gallate inhibits insulin stimulation of adipocyte glucose uptake via the AMP-activated protein kinase pathway

Hui-Chen Ku(1), Chi-Fen Hsieh(1), Pei-Hua Tsai(1), Yung-Chia Hsu(1), Hsin-Huei Chang(1), Chung-Cheng Kao(2), Yi-Wei Tsuei(2), Li-Jane Shih(2), Low-Tone Ho(3), Liang-Yi Wu(4), Yung-Hsi Kao(1)
(1)Department of Life Science, National Central University, (2)Department of Emergency, Taoyuan Armed Forces General Hospital, (3)Department of Internal Medicine, Taipei Veterans General Hospital, (4)Department of Bioscience Technology, Chung Yuan Christian University
ENDOCRINE JOURNAL 57 (suppl.2-2) S434-S434, 2010.

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P2-15-1 Interleukin-4 action in the brain exacerbates hypothalamic inflammation and weight gain during high fat feeding

Shinsuke Oi, Joshua P.Thaler, Brent E.Wisse, Gregory J.Morton, Michael W.Schwartz
Department of Medicine, Diabetes and Obesity Center of Excellence, University of Washington
ENDOCRINE JOURNAL 57 (suppl.2-2) S434-S434, 2010.

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P2-15-2 Changes of expressions of neuronal plasticity-related factors in the brain of diet-induced obese mice

Nobuko Yamada, Goro Katsuura, Yukari Ochi, Ken Ebihara, Toru Kusakabe, Kiminori Hosoda, Kazuwa Nakao
Division of Endocrinology and Metabolism, Department of Medicine and Clinical Science, Kyoto University
ENDOCRINE JOURNAL 57 (suppl.2-2) S434-S435, 2010.

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P2-15-3 Sex difference in pre-puberty, early puberty and adult rats on energy metabolism

Yukari Date, Eri Mutoh, Sayaka Akieda, Kazuyo Senba
Frontier Science Research Center, University of Miyazaki
ENDOCRINE JOURNAL 57 (suppl.2-2) S435-S435, 2010.

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P2-15-4 Interleukin-10 improves insulin sensitivity with STAT3 phosphorylation in hypothalamus

Isao Usui(1), Shiho Fujisaka(1), Yukiko Kanatani(1), Aminuddin Aminuddin(1), Agussalim Bukhari(1), Satoko Senda(1), Koichi Tsuneyama(2), Kazuyuki Tobe(1)
(1)First Department of Internal Medicine, University of Toyama, (2)Department of Diagnostic Pathology, University of Toyama
ENDOCRINE JOURNAL 57 (suppl.2-2) S435-S435, 2010.

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P2-15-5 The anorexic effect of the MCH1 receptor antagonist, TPI1361-17

Hiroshi Nagasaki(1), Shinjae Chung(2), Yumiko Saito(3), Yoji Hamada(1), Yutaka Oiso(4), Olivier Civelli(2)
(1)Department of Metabolic Medicine, Nagoya University, Graduate School of Medicine, (2)Dept.Pharmacology, University of California, (3)laboratory for Behavioral Neuroscience, Graduate School of Integrated Arts and Sciences, Hiroshima University, (4)dept.Endocrinology and diabetes, Nagoya University, Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S435-S435, 2010.

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P2-15-6 Neuronal histamine H1-receptor is involved in the diurnal rhythm of energy intake and expenditure in mice

Takayuki Masaki, Takanobu Shimasaki, Koro Gotoh, Seiichi Chiba, Isao Katsuragi, Tetsuya Kakuma, Hironobu Yoshimatsu
The First Department of Internal Medicine, University of Oita
ENDOCRINE JOURNAL 57 (suppl.2-2) S435-S435, 2010.

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P2-15-7 Identification of bioactive peptides associated with the metabolic syndrome

Takashi Miyazawa, Mikiya Miyazato, Morikatsu Yoshida, Kazutomo Sawai, Kenji Mori, Kenji Kangawa
Department of Biochemistry, National Cardiovascular Center Research Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S435-S436, 2010.

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P2-15-8 A proteome analysis of obesity tissue from early phase of diet induced obesity mice

Rong Fan
Department of Endocrinology, Changzheng Hospital, Second Military Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S436-S436, 2010.

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P2-16-1 Roles of PrRP and oxytocin receptor in stress-induced increase of energy expenditure

Yuki Takayanagi(1), Katsuhiko Nishimori(2), Tatsushi Onaka(1)
(1)Department of Physiology, Jichi Medical University, (2)Laboratory of Molecular Biology, Tohoku University Graduate School of Agricultural Science
ENDOCRINE JOURNAL 57 (suppl.2-2) S436-S436, 2010.

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P2-16-2 Molecular mechanisms of hypotriglyceridemia and resistance to high-fat-diet-induced obesity in PDIP1 knockout mice

Satoshi Yoshino, Tetsurou Satoh, Takuya Tomaru, Hiroyuki Shimizu, Yasuyo Ariyama, Takahiro Ishizuka, Koshi Hashimoto, Masanobu Yamada, Masatomo Mori
Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S436-S436, 2010.

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P2-16-3 MT1-MMP directs diet-dependent adipose tissue remodeling and defines a human obesity trait

Tae-Hwa Chun(1), Mayumi Inoue(1), Hiroko Morisaki(2), Itaru Yamanaka(2), Yoshihiro Miyamoto(2), Tomonori Okamura(2), Kaoru Kusubata-Sato(3), Stephen J.Weiss(1)
(1)University of Michigan, (2)National Cardiovascular Center Research Institute, (3)IMSUT, University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S436-S436, 2010.

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P2-16-4 Thermogenic UCP1 enhances anorexigenic effect of leptin in mice

Yuko Okamatsu-Ogura(1), Akira Terao(1), Kazuhiro Kimura(1), Masayuki Saito(2)
(1)Graduate School of Veterinary Medicine, Hokkaido University, (2)Department of Nutrition, School of Nursing and Nutrition, Tenshi College
ENDOCRINE JOURNAL 57 (suppl.2-2) S437-S437, 2010.

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P2-16-5 Regulation of thermogenesis, appetite and hair color by salt-inducible kinase 2(SIK2)

Hiroshi Takemori(1), Ayako Kumagai(1), Tatsuya Uebi(1), Nanao Horike(1), Say Viengchareun(2), Mark Lombes(2)
(1)National Institute of Biomedical Innovation, (2)Inserm U693, Univ. Paris-Sud, Faculte de Medecine Paris-Sud
ENDOCRINE JOURNAL 57 (suppl.2-2) S437-S437, 2010.

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P2-16-6 Variations in the 5'-flanking region of the neuropeptide Y2 receptor gene are associated with serum high-density lipoprotein cholesterol levels.

Masayo Tanaka, Etsuko Takiguchi, Kanna Okayama, Keiko Tanida, Hidesuke Kaji
Division of Physiology and Metabolism, University of Hyogo
ENDOCRINE JOURNAL 57 (suppl.2-2) S437-S437, 2010.

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P2-16-7 Brown adipose tissue protects against age-related obesity in humans

Takeshi Yoneshiro(1), Mami Matsushita(1), Kumiko Watanabe(1), Sayuri Aita(1), Yuko Okamatsu-Ogura(2), Toshimitsu Kameya(3), Kunihiro Nakada(3), Yuko Kawai(3), Masayuki Tsujisaki(3), Masayuki Saito(1)
(1)Department of Nutrition, School of Nursing and Nutrition, Tenshi College, (2)Department of Biomedical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, (3)LSI Sapporo Clinic
ENDOCRINE JOURNAL 57 (suppl.2-2) S437-S437, 2010.

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P2-16-8 Adipose tissue transplantation for lipodystrophy

Eisaku Mori, Kiminori Hosoda, Michio Noguchi, Junji Fujikura, Tsutomu Tomita, Shinji Odori, Masaki Naito, Toru Kusakabe, Ken Ebihara, Kazuwa Nakao
The Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S437-S438, 2010.

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P2-17-1 Fetal growth and metabolic change in high-fat diet(HFD)-induced obese pregnant mice

Nao Murabayashi, Takashi Sugiyama, Lingyun Zhang, Takashi Umekawa, Norimasa Sagawa
Obstetrics and Gynecology, University of Mie
ENDOCRINE JOURNAL 57 (suppl.2-2) S438-S438, 2010.

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P2-17-2 The effect of childhood obese or lean on the adulthood insulin resistance in OLETF rats

Daisuke Nakano, Suwarni Diah, Hirofumi Hitomi, Akira Nishiyama
Department of Pharmacology, Kagawa University
ENDOCRINE JOURNAL 57 (suppl.2-2) S438-S438, 2010.

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P2-17-3 Sex differences in fetal programming of metabolic syndrome in rats

Eiko Nagata, Yuichi Nakagawa, Rie Yamaguchi, Shuji Sai, Yasuko Fujisawa, Takehiko Ohzeki
Department of Pediatrics, Hamamatsu University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S438-S438, 2010.

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P2-17-4 Timing of adiposity rebound seems not to be related to body weight gain during infancy

Satomi Koyama(1), Go Ichikawa(1), Yuzuru Yamazaki(1), Megumi Kojima(1), Naoto Shimura(1), Toshimi Sairenchi(2), Osamu Arisaka(1)
(1)Department of Pediatric, Dokkyo Medical University, (2)Department of Public Health, Dokkyo Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S438-S439, 2010.

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P2-17-5 Omental and subcutaneous adipose tissue steroid hormone level in women

T.Kinoshita(1), Y.Watanabe(2), Seijiro Honma(2)
(1)Department of Obsterics and Gynecology, Sakura Hospital, University of Toho, (2)ASKA Medical Co.Ltd
ENDOCRINE JOURNAL 57 (suppl.2-2) S439-S439, 2010.

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P2-17-6 Impacts of Kampo medicines in obese women over middle age

Chie Nakano, Yumiko Haruna, Seiya Orito, Remi Yoshikata, Shoko Shimizu, Ken Ishitani, Kazunori Hashimoto, Hiroaki Ohta
Department of Obstetric and Gynecology, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S439-S439, 2010.

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P2-17-7 An exploratory study on transition from the metabolic syndrome to lifestyle-related diseases

Yoshiko Onoe, Chie Nakano, Yumiko Haruna, Seiya Orito, Ken Ishitani, Kazunori Hashimoto, Hiroaki Ohta
Department of Obstetrics and Gynecology, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S439-S439, 2010.

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P2-18-1 Endotoxin directly acts on hepatic stellate cells during the development of nonalcoholic steatohepatitis

Noriko Sakamoto(1), Keiichi Ikeda(2), Yuri Inada(1), Yuko Takada(1), Katsuyoshi Tojo(1), Naoko Tajima(1), Kyoko Ishii(3), Goshi Shiota(3)
(1)Division of Diabetes and Endocrinology, Department of Internal Medicine, The Jikei University School of Medicine, (2)Department of Pharmacology, The Jikei University School of Medicine, (3)Department of Genetic Medicine and Regenerative Therapeutics, Graduate School of Medicine, Tottori University
ENDOCRINE JOURNAL 57 (suppl.2-2) S439-S439, 2010.

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P2-18-2 The expression of MCP1 and NFkB in the liver of non-alcholic steatohepatitis(NASH)model

Toshio Kumai(1), Minoru Watanabe(1), Yuko Takeba(1), Naoki Matsumoto(1), Sachiko Takenoshita(1), Toshie Harimoto(1), Junki Koike(2), Shinichi Kobayashi(1)
(1)Department of Pharmacology, St.Marianna University School of Medicine, (2)Department of Pathology, St.Marianna University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S440-S440, 2010.

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P2-18-3 RNA binding motif protein on the X chromosome(RBMX), a novel key molecule for developing metabolic syndrome and NASH

Yasuhiro Maeno, Yoshihiko Nishio, Yoshio Nagai, Tadashi Takemoto, Osamu Sekine, Yasushi Omura, Masateru Ushio, Hiroshi Kimura, Atsunori Kashiwagi, Hiroshi Maegawa
Shiga University of Medical Science
ENDOCRINE JOURNAL 57 (suppl.2-2) S440-S440, 2010.

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P2-18-4 A role of the diet and LOX-1-induced oxidative stress in the onset of NASH

Yuzaburo Uetake, Tatsuo Shimosawa, Hitoshi Ikeda, Yutaka Yatomi, Toshiro Fujita
The University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S440-S440, 2010.

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P2-18-5 TNF-α induced hepatic steatosis in mice by enhancing gene expression of sterol regulatory element binding protein-1c(SREBP-1c)

Mizuki Endo
Department of Internal Medicine, Faculty of Medicine, Oita University
ENDOCRINE JOURNAL 57 (suppl.2-2) S440-S440, 2010.

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P2-18-6 The role of spleen in regulating diet-induced steatohepatitis in rats

Megumi Inoue, Koro Gotoh, Masataka Seike, Takayuki Masaki, Tetsuya Kakuma, Hironobu Yoshimatsu
Department of Internal Medicine 1, Faculty of Medicine, , Oita University
ENDOCRINE JOURNAL 57 (suppl.2-2) S440-S441, 2010.

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P2-18-7 The study on the relevant factors of nonalcoholic fatty liver disease in Dongcheng District in Beijing

Lingling Xu, Hong-ding Xiang, Huabing Zhang, Wei Chen, Jing-hui Fang
Department of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science
ENDOCRINE JOURNAL 57 (suppl.2-2) S441-S441, 2010.

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P2-18-8 The course of non alcoholic fatty liver disease(NAFLD)in non-obese subjects:A longitudinal observation study

Joo Hyung Kim, Ji Mi Moon, Juri Park, Yun Jeong Lee, Hee Young Kim, Sin Gon Kim, Dong Seop Choi
Division of Endocrinology and Metabolism, Internal Medicine Department, Korea University Anam Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S441-S441, 2010.

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P3-1-1 Localization of novel neuroendocrine regulatory peptides, NERP-1 and-2, in human brain and pancreas

Takashi Matsuo(1), Hideki Yamaguchi(1), Haruaki Kageyama(2), Kazuki Sasaki(3), Seiji Shioda(2), Naoto Minamino(3), Masamitsu Nakazato(1)
(1)Division of Neurology, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Miyazaki Medical College, University of Miyazaki, (2)Department of Anatomy, Showa University School of Medicine, (3)Department of Pharmacology, National Cardiovascular Center Research Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S441-S441, 2010.

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P3-1-2 Endogenous molecular forms of neuroendocrine regulatory peptides and their proteolytic processing from VGF protein in the rat

Emi Mishiro(1), Kazuki Sasaki(1), Hideki Yamaguchi(2), Masamitsu Nakazato(2), Yoshinori Satomi(3), Toshifumi Takao(3), Naoto Minamino(1)
(1)Department of Pharmacology, National Cardiovascular Center Research Institute, (2)Department of Neurology, Respirology, Endocrinology and Metabolism, Faculty of Medical College, University of Miyazaki, (3)Laboratory of Protein Profiling and Functional Proteomics, Institute for Protein Research, Osaka University
ENDOCRINE JOURNAL 57 (suppl.2-2) S441-S442, 2010.

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P3-1-3 Nesfatin suppresses feeding and stimulates the hypothalamo-pituitary-gonadal axis

John A Tadross, Michael Patterson, Katie J.Wynne, Sejal Patel, Keisuke Suzuki, Mohammad A.Ghatei, Stephen R.Bloom
Department of Investigative Medicine, Imperial College London
ENDOCRINE JOURNAL 57 (suppl.2-2) S442-S442, 2010.

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P3-1-4 α-Melanocyte-stimulating hormone-Induced anorexia is partly mediated by nesfatin-1 in the hypothalamic paraventricular nucleus

Udval Sedbazar, Yuko Maejima, Masanori Nakata, Toshihiko Yada
Division of Integrative Physiology, Department of Physiology, Jichi Medical University, School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S442-S442, 2010.

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P3-1-5 The role of the MCH system in regulating the HPT(Hypothalamus-Pituitary-Thyroid)axis

Shinjae Chung(1), Hiroshi Nagasaki(2), Timothy Wong(1), Olivier Civelli(1)
(1)University of California, (2)Hiroshi Nagasaki Dept.of Metabolic Medicine, School of Medicine, Nagoya University
ENDOCRINE JOURNAL 57 (suppl.2-2) S442-S442, 2010.

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P3-1-6 Orphan receptors Nurr-1/Nur77 are involvement in corticotropin-releasing hormone and urocortin induction of tyrosinase-related protein type 1 in human melanocytes

Shinobu Takayasu(1), Yasumasa Iwasaki(2), Kazunori Kageyama(1), Toshihiro Suda(1)
(1)Departments of Endocrinology and Metabolism, Hirosaki University School of Medicine, (2)Departments of Endocrinology, Metabolism, and Nephrology, Kochi Medical School, Kochi University
ENDOCRINE JOURNAL 57 (suppl.2-2) S442-S443, 2010.

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P3-1-7 Gene expression and electrophysiological studies indicating that the central serotonin system is suppressed by ghrelin in rodents

Caroline Hansson(1), Magdalena Taube(1), David Haage(2), Emil Egecioglu(1), Suzanne L.Dickson(1)
(1)Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, (2)Integrative Medical Biology, Umea University
ENDOCRINE JOURNAL 57 (suppl.2-2) S443-S443, 2010.

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P3-1-8 Assessment of somatostatin receptor expression in predicting results of PRRT(peptide receptor radionuclide therapy)in disseminated neuroendocrine tumours(NET)

Alicja B.Hubalewska-Dydejczyk(1), Anna Sowa-Staszczak(1), Malgorzata Trofimiuk(1), Agnieszka Stefanska(1), Wojciech Wierzchowski(2), Jolanta Kunikowska(3), Dorota Pach(1), Romana Tomaszewska(2)
(1)Endocrinology Department, Nuclear Medicine Unit, Medical College, Jagiellonian University, (2)Pathology Department, Medical College, Jagiellonian University, (3)Nuclear Medicine Department, Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S443-S443, 2010.

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P3-2-1 Identification of novel peptides for orphan GPCRs in drosophila

Takanori Ida, Takahiro Sato, Masayasu Kojima
Division of Molecular Genetics, Institute of Life Science, Kurume University
ENDOCRINE JOURNAL 57 (suppl.2-2) S443-S443, 2010.

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P3-2-2 The physiological role of ghrelin in thermoregulation

Takahiro Sato(1), Yuki Nakamura(1), Takanori Ida(1), Hiroharu Mifune(2), Kenji Kangawa(3), Masayasu Kojima(1)
(1)Molecular Genetics, Institute of Life Science, Kurume University, (2)Institute of Animal Experimentation, School of Medicine, Kurume University, (3)Department of Biochemistry, National Cardiovascular Center Research Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S443-S443, 2010.

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P3-2-3 Establishment of a transgenic mouse model of ghrelinoma

Hiroshi Iwakura(1), Hiroyuki Ariyasu(1), Yushu Li(1), Naotetsu Kanamoto(2), Mika Bando(1), Go Yamada(2), Hiroshi Hosoda(3), Kiminori Hosoda(2), Akira Shimatsu(4), Kazuwa Nakao(1), Kenji Kangawa(3), Takashi Akamizu(1)
(1)Ghrelin Research Project, Translational Research Center, Kyoto University Hospital, (2)Department of Medicine and Clinical Science, Endocrinology and Metabolism, Kyoto University Graduate School of Medicine, (3)National Cardiovascular Center Research Institute, (4)Clinical Research Institute for Endocrine Metabolic Diseases, National Hospital Organization
ENDOCRINE JOURNAL 57 (suppl.2-2) S444-S444, 2010.

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P3-2-4 First non-teleost growth hormone-releasing hormone receptor(GHRHR)identified in lungfish

Kal Van Tam, Leo T.O.Lee, Billy K.C.Chow
School of Biological Sciences, University of Hong Kong
ENDOCRINE JOURNAL 57 (suppl.2-2) S444-S444, 2010.

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P3-2-5 Endogenously generated 2-arachidonoylglycerol plays an inhibitory role in corticotropin-releasing factor-induced activation of central sympatho-adrenomedullary outflow in rats

Takahiro Shimizu, Lianyi Lu, Kunihiko Yokotani
Dept.of Pharmacol., Sch.of Medicine, Kochi Univ
ENDOCRINE JOURNAL 57 (suppl.2-2) S444-S444, 2010.

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P3-2-6 Modulatory role of Versons glands peptide in insect metamorphosis

Muraleedharan Damodaran
Center for Arthropod Bioresources and Biotechnology, Kerala University
ENDOCRINE JOURNAL 57 (suppl.2-2) S444-S444, 2010.

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P3-2-7 Cryptides:Discovery of functional cryptic peptides hidden in protein structures and investigation of their intracellular signaling mechanisms

Hidehito Mukai(1), Tetsuo Seki(2), Yoshinori Hokari(2), Akiyoshi Fukamizu(2), Yoshiaki Kiso(1)
(1)Department of Medicinal Chemistry, Kyoto Pharmaceutical University, (2)Graduate School of Life and Environmental Sciences, University of Tsukuba
ENDOCRINE JOURNAL 57 (suppl.2-2) S444-S445, 2010.

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P3-3-1 Association of adrenomedullin2/intermedin gene insertion/deletion polymorphism with blood pressure, renal function and silent cerebrovascular lesions in a Japanese general population:The Ohasama study

Takuo Hirose(1), Kazuhito Totsune(2), Hirohito Metoki(2), (3), Takuya Kawamura(2), Azusa Hara(2), Kei Asayama(1), Takeo Kondo(4), Masahiro Kikuya(2), Takayoshi Ohkubo(1), Shin-ichi Izumi(4), Kazuhiro Takahashi(5), Yutaka Imai(2)
(1)Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Phamaceutical Sciences and Medicine, (2)Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences and Medicine, (3)Department of Medical Genetics, Tohoku University Graduate School of Medicine, (4)Department of Physical Medicine and Rehabilitation, Tohoku University Graduate School of Medicine, (5)Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S445-S445, 2010.

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P3-3-2 Characterization of the trafficking interactions between endocrine G protein-coupled receptors(GPCRs)and receptor activity-modifying proteins(RAMPs)

Kenji Kuwasako(1), Kazuo Kitamura(2), Sayaka Nagata(2), Johji Kato(1)
(1)Frontier Science Research Center, University of Miyazaki, (2)Circulation and Body Fluid Regulation, Faculty of Medicine, University of Miyazaki
ENDOCRINE JOURNAL 57 (suppl.2-2) S445-S445, 2010.

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P3-3-3 Biological functions of adrenomedullin family in teleost fish

Maho Ogoshi(1), Shigenori Nobata(2), Koji Inoue(2), Kakon Nag(3), Yoshio Takei(2), Shigehisa Hirose(1)
(1)Department of Biological Sciences, Tokyo Institute of Technology, (2)Ocean Research Institute, University of Tokyo, (3)Department of Pathology and Molecular Medicine, McMaster University
ENDOCRINE JOURNAL 57 (suppl.2-2) S445-S445, 2010.

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P3-3-4 Natriuretic peptide receptor guanylyl cyclase-A signaling exerts antagonistic effects on the local renin-angiotensin-aldosterone system in kidney

Yoshihisa Ogawa(1), Masashi Mukoyama(1), Hideki Yokoi(1), Masato Kasahara(1), Kiyoshi Mori(1), Tetsuro Yoshioka(1), Yoko Saito(1), Takashige Kuwabara(1), Hirotaka Imamaki(1), Tomoko Kawanishi(1), Kenichi Koga(1), Akira Ishii(1), Ichiro Kishimoto(2), Akira Sugawara(1), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)National Cardiovascular Center Research Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S446-S446, 2010.

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P3-3-5 The role of C-type natriuretic peptide in development and function of peripheral sensory neurons

Ichiro Kishimoto(1), (2), Takeshi Tokudome(2), Hideki Chusho(3), Naohisa Tamura(3), Kazuwa Nakao(3), Kenji Kangawa(2)
(1)Department of Atherosclerosis and Diabetes, National Cardiovascular Center, (2)Department of Biochemistry, National Cardiovascular Center, (3)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S446-S446, 2010.

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P3-3-6 The therapeutic potential of ghrelin in cardiac diseases-The role of peripheral nerve

Ichiro Kishimoto(1), Takeshi Tokudome(2), Daryl Schwenke(3), Takeshi Soeki(2), Noritoshi Nagaya(2), Kenji Kangawa(2)
(1)Department of Atherosclerosis and Diabetes, National Cardiovascular Center, (2)Department of Biochemistry, National Cardiovascular Center, (3)Department of Physiology, School of Medical Sciences, University of Otago
ENDOCRINE JOURNAL 57 (suppl.2-2) S446-S446, 2010.

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P3-3-7 Distinct tissue distribution of salusin-α and salusin-β expression in the rat

Noriko Suzuki, Masayoshi Shichiri, Tae Nakano, Chisato Nakayama, Yukio Hirata
Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate School
ENDOCRINE JOURNAL 57 (suppl.2-2) S446-S447, 2010.

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P4-1-1 Quantitative and qualitative change in TSH receptor antibody after radioactive-iodine therapy for severe Graves hyperthyroidism

Ken Okamura, Sachiko Bandai, Megumi Fujikawa, Mitsuo Iida
The Second Department of Internal Medicine, Kyushu University
ENDOCRINE JOURNAL 57 (suppl.2-2) S447-S447, 2010.

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P4-1-2 TSH is not a reliable parameter for monitoring thyroid function in hyperthyroid patients during antithyroid treatment.

Cristina M.V.Ghervan, Andra Andreescu-Pasca, Gheorghe Dragotoiu, Ileana M.Duncea
Endocrinology Department, University of Medicine and Pharmacy
ENDOCRINE JOURNAL 57 (suppl.2-2) S447-S447, 2010.

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P4-1-3 Elevated serum BAFF concentration in patients with Graves' disease

Sumito Sunagawa(1), Tsuyoshi Kouki(1), Ayako Miyara(1), Kouichi Yabiku(1), Yoshitaka Nagasawa(2), Yukio Ochi(3), Ichiro Komiya(1), Hiroaki Masuzaki(1)
(1)Department of Endocrinology and Metabolism, University of the Ryukyus, (2)Northern Okinawa Medical Center, (3)Research Institute for Production Development
ENDOCRINE JOURNAL 57 (suppl.2-2) S447-S447, 2010.

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P4-1-4 Association of a C/T single nucleotide polymorphism in programmed cell death 1 gene with Graves disease in Japanese patients

Tsuyoshi Kouki, Sumito Sunagawa, Ayako Miyara, Ichiro Komiya, Hiroaki Masuzaki
Department of Endocrinology and Metabolism, University of the Ryukyus School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S447-S447, 2010.

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P4-1-5 Association between thyroid status and glucose intolerance in hyperthyroid patients

Wismandari Wisnu, Pradana Soewondo, Imam Subekti
Metabolic Endocrine Division, Internal Medicine Department, University of Indonesia
ENDOCRINE JOURNAL 57 (suppl.2-2) S448-S448, 2010.

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P4-1-6 Prevalence of anti-collagen XIII antibodies in Japanese thyroid-associated ophthalmopathy patients

Jun-ichi Tani, Kazuhisa Muraishi, Kentaro Yamada, Yuji Hiromatsu
The Department of Endocrinology and Metabolism, Kurume University school of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S448-S448, 2010.

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P4-1-7 Flushing dose therapy of immunosuppressive agents for thyroid-associated ophthalmopathy

Yongquan Shi, Wei Tang, Yi Bao, Junjie Zou, Xiangfang Chen, Jiaoyang Zheng, Zhimin Liu
Department of Endocrinology, Changzheng Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S448-S448, 2010.

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P4-1-8 Thyroid artery embolization(TAE)as an alternative method of treatment of hyperthyroidism

Grzegorz W.Kaminski, Andrzej Jaroszuk, Krzysztof Brzozowski
Military Institute of Health Services
ENDOCRINE JOURNAL 57 (suppl.2-2) S448-S448, 2010.

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P4-2-1 Incidence of hypoparathyroidism in 234 patients with papillary microcarcinoma after total thyroidectomy with or without central neck dissection

Nikola Besic, Rok Petric, Marko Hocevar, Franc Pompe, Erik Brecelj, Damijan Bergant
Department of surgical oncology, Institute of Oncology
ENDOCRINE JOURNAL 57 (suppl.2-2) S449-S449, 2010.

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P4-2-2 Influence of gender on incidences and therapeutic outcomes of thyroid cancer

Jen-der Lin(1), Bie Yu Huang(1), Chuen Hsuen(2), Miaw-Jene Liou(1), Tzu-Chieh Chao(3)
(1)Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, (2)Department of Pathology, Chang Gung Memorial Hospital, Chang Gung University, (3)Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University
ENDOCRINE JOURNAL 57 (suppl.2-2) S449-S449, 2010.

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P4-2-3 Decreased 1-25 dihydroxyvitamin D3 peripheral blood serum concentration in patients with thyroid cancers

Tomasz A.Stepien(1), Karolina Tosik(2), Roman Krupinski(1), Jan Sopinski(1), Krzysztof Kuzdak(1), Jan Komorowski(3), Hanna Lawnicka(2), Henryk Stepien(2)
(1)Departament of Endocrine and General Surgery, Medical University of Lodz, (2)Department of Immunoendocrinology, Medical University of Lodz, (3)Department of Clinical Endocrinology, Medical University of Lodz
ENDOCRINE JOURNAL 57 (suppl.2-2) S449-S449, 2010.

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P4-2-4 The clinical value of 18F-FDG PET/CT for detection of thyroid carcinoma in Japanese normal subjects by health checkup system:Comparison with thyroid ultrasonography

Hironari Kimura(1), (2), Gen Sarashina(1), Katsuyuki Kobayashi(1), Yoshiko Miyatake(1), Masao Ono(1), Tatsuya Kato(1), Hiromi Ogura(1), Izuru Ochiai(1), Kanji Sato(2), Kazue Takano(2), Seiei Yasuda(1), (3)
(1)Health Evaluation and Promotion Center, Yotsuya Medical Cube, (2)Department of Internal Medicine, Institute of Clinical endocrinology, Tokyo Women's Medical University, (3)Department of Surgery, Tokai University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S449-S450, 2010.

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P4-2-5 Sarcoidosis associated with papillary thyroid cancer

Albert Makarov(1), (2), (3), Kyunnyay Loskutova(1), Larisa Krivoshapkina(3), Violetta Arzhakova(2), Alexandra Innokentyeva(1)
(1)National Center for Medicine, (2)Medical Institute at the Yakut State University, (3)Federal service on surveillance in healthcare and social development of Republic of Sakha
ENDOCRINE JOURNAL 57 (suppl.2-2) S450-S450, 2010.

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P4-2-6 The use of HDAC inhibitor valproic acid and PPAR-gamma agonist pioglitazone in the treatment of anaplastic carcinoma of the thyroid

Hitoshi Noguchi, Tsukasa Murakami, Hiroto Yamashita, Yasushi Noguchi, Shinya Uchino, Shiro Noguchi
Noguchi Thyroid Clinic and Hospital Foundation
ENDOCRINE JOURNAL 57 (suppl.2-2) S450-S450, 2010.

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P4-2-7 Surgical treatment of papillary thyroid carcinoma in children and adolescents

Radan R.Dzodic(1), Ivan Z.Markovic(1), Igor Djurisic(1), Marko Buta(1), Gordana Pupic(1), Zorka Milovanovic(1), Boban Stanojevic(2)
(1)Institute of oncology and radiology of Serbia, University of Belgrade, (2)Institute for Nuclear Science Vinca
ENDOCRINE JOURNAL 57 (suppl.2-2) S450-S450, 2010.

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P4-2-8 Thyroglossal duct cyst thyroid carcinoma and surgical strategy after eleven cases

Radan R.Dzodic, Ivan Z.Markovic, Marko Buta, Igor Djurisic, Gordana Pupic, Zorka Milovanovic
Institute of oncology and radiology of Serbia, University of Belgrade
ENDOCRINE JOURNAL 57 (suppl.2-2) S450-S450, 2010.

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P4-3-1 Mutational and clinicopathological analysis of papillary thyroid carcinoma in Serbian patients

Boban Stanojevic(1), Radan R.Dzodic(2), Vladimir Saenko(3), Zorka Milovanovic(2), Gordana Pupic(2), Ognjen Zivkovic(2), Ivan Markovic(2), Igor Djurisic(2), Marko Buta(2), Zoran Tomasevic(2), Tatiana Rogounovitch(3), Norito Mitsutake(1), Mariko Mine(4), Yoshisada Shibata(4), Shunichi Yamashita(1), (3)
(1)Department of Molecular Medicine, Atomic Bomb Disease Institute, Nagasaki University, Graduate School of Biomedical Science, (2)Institute for Oncology and Radiology of Serbia, (3)Department of International Health and Radiation Research, Nagasaki University Graduate School of Biomedical Sciences, (4)Department of Biomedical Statistics, Nagasaki University Graduate School of Biomedical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S451-S451, 2010.

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P4-3-2 Expression of folate receptor type α gene in thyroid papillary carcinoma

Naotetsu Kanamoto(1), Yudai Takeuchi(1), Yoshiyuki Hattori(2), Mami Yoshida(1), Eri Kondo(1), Go Yamada(1), Toshihito Fujii(1), Misa Saijo(1), Takuo Nambu(1), Masako Miura(1), Akihiro Yasoda(1), Hiroshi Arai(1), Yoshie Maitani(2), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Institute of Medicinal Chemistry, Hoshi University
ENDOCRINE JOURNAL 57 (suppl.2-2) S451-S451, 2010.

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P4-3-3 Simultaneous determination of tumor clonality and mutant BRAF oncogene detects the molecular diversity of papillary thyroid carcinoma

Tatiana Rogounovitch(1), Vladimir Saenko(2), Alexander Abrosimov(3), Elena Furminskaya(4), Eugeny Lushnikov(4), Norisato Mitsutake(1), Shunichi Yamashita(1), (2)
(1)Department of Molecular Medicine, Nagasaki University, (2)Department of International Health and Radiation Research, Nagasaki University, (3)Department of Pathology, Endocrinology Research Center, Moscow, Russian Federation, (4)Department of Pathology, Medical Radiological Research Center RAMS, Obninsk, Russian Federation
ENDOCRINE JOURNAL 57 (suppl.2-2) S451-S451, 2010.

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P4-3-4 DNA damage response genes as genetic factors modifying risk of radiation-related thyroid cancer

Vladimir Saenko(1), Tatiana Rogounovitch(2), Meiko Takahashi(3), Chanavee Ratanajaraya(3), Norisato Mitsutake(2), Valentina Drozd(4), Fumihiko Matsuda(3), Shunichi Yamashita(1), (2)
(1)Department of International Health and Radiation Research, Nagasaki University, (2)Department of Molecular Medicine, Nagasaki University, (3)Center for Genomic Medicine, Kyoto University, (4)Thyroid Research Group, Belarussian Medical Academy for Postgraduate Education, Minsk, Republic of Belarus
ENDOCRINE JOURNAL 57 (suppl.2-2) S451-S452, 2010.

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P4-3-5 The effects of growth inhibitory peptide on follicular thyroid cancer cell growth, migration, and invasion

Shih-Che Hua(1), (5), Syue-Yi Chen(2), Chieh-Hisang Lu(1), Yu-Ting Kao(3), Hui-I Yu(1), Ping-Tzu Chen(2), Tien-Chun Chang(4), Ying-Ray Lee(2)
(1)Division of Endocrinology and Metabolism, Department of Internal Medicine, Chia-Yi Christian Hospital, (2)Department of Biomedical Sciences, Chiayi Christian Hospital, (3)Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, (4)Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, National Taiwan University, (5)Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University
ENDOCRINE JOURNAL 57 (suppl.2-2) S452-S452, 2010.

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P4-3-6 Papillary thyroid carcinoma with lung metastasis complicated with tension hemothorax

Kuo-Yang Lee, Tien-Chun Chang
Endocrine and metabolism department, National Taiwan university hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S452-S452, 2010.

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P4-3-7 Follicular variant of papillary thyroid carcinoma presenting as bone metastasis

Asma Ahmed, Najmul Islam, Maseeh Uzama
The Aga Khan University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S452-S452, 2010.

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P4-3-8 Pulmonary metastasis in well differentiated thyroid carcinoma of unknown malignant potential:A case presentation and review of literature

Asma Ahmed, Najmul Islam, Maseeh Uzama
The Aga Khan University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S452-S452, 2010.

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P4-3-9 A case of an unusual presentation of follicular thyroid carcinoma

Goknur Yorulmaz, Aysen Akalin, Evrim Ciftci, Ozgul Pasaoglu
Eskisehir Osmangazi University
ENDOCRINE JOURNAL 57 (suppl.2-2) S453-S453, 2010.

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P4-4-1 Production rates and turnover of thyroid hormone in hypothyroid rats induced by thyroidectomy and iodine-deficiency

Hidenori Nagao(1), Tetsuya Imazu(1), Hiroyuki Hayashi(2), Kouichi Minato(1), Akira Fujikata(1)
(1)Pharmacokinetics Research Department, ASKA Pharmaceutical Co, Ltd, (2)Synthetic Research Department, ASKA Pharmaceutical Co., Ltd
ENDOCRINE JOURNAL 57 (suppl.2-2) S453-S453, 2010.

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P4-4-2 Iodine deficiency in pregnancy in a iodine replete area of eastern India

Anirban Mazumdar(1), Arvinda Jaiswal(2), Suniti Ghosh Chatterjee(2), Sudip Chatterjee(1)
(1)Endocrinology Unit, Vivekananda Institute of Medical Sciences, West Bengal University of Health Sciences, (2)Department of Home Science, University of Calcutta
ENDOCRINE JOURNAL 57 (suppl.2-2) S453-S453, 2010.

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P4-4-3 Hypothyroidism caused by an iodine deficiency and iodine level in enteric formulas

Hiroko Kodama, Katsuaki Siga, Fumiaya Kaga, Yoichi Izumi, Chie Fujisawa
Department of Pediatrics, Teikyo University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S453-S453, 2010.

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P4-4-4 The chronic autoimmune thyroiditis-Characteristics of clinical expression in perimarine zone of romania

Eduard Circo
Endocrinology Department, Ovidius University Constanta
ENDOCRINE JOURNAL 57 (suppl.2-2) S453-S454, 2010.

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P4-4-5 Can we predict the course of subacute thyroiditis?

Menaka Ramprasad(1), J.Sandeep(2), B.S.Narendra(2), A.Manjunath(2), Arpandev Bhattacharyya(2)
(1)Apollo Hospitals, (2)Manipal Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S454-S454, 2010.

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P4-4-6 Can clinico-biochemical parameters differrentiate Graves' disease from thyroiditis?

Menaka Ramprasad(1), J.Sandeep(2), B.S.Narendra(2), M.Sehgal(2), Arpandev Bhattacharyya(2)
(1)Apollo Hospitals, (2)Manipal Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S454-S454, 2010.

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P4-4-7 Serum concentrations of adiponectin, leptin and IL-6 in Hashimoto's thyroidits women

Lucyna Sieminska, Beata Kos-Kudla, Bogdan Marek, Joanna Glogowska-Szelag, Dariusz Kajdaniuk, Mariusz Nowak, Wanda Foltyn, Janusz Strzelczyk
Department of Pathophysiology and Endocrinology, Silesian Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S454-S454, 2010.

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P4-4-8 Clinical experiences of 5 cases of thyroid storm:Case presentations and review of literature

Yoshiko Morohoshi(1), Ayako Yoshimoto(1), Kazumi Hayashi(1), Mina Yuzawa(1), Kenji Tagai(1), Takanori Ebisawa(1), (2), Ryouiti Aizawa(1), Chihiro Shikata(1), Masami Nemoto(1), Nobuakira Takeda(1), Tatsuya Koyama(3), Kensuke Tsutsui(3), Shingo Seki(3), Katsuyoshi Tojo(4), Naoko Tajima(4)
(1)Department of General Internal Medicine, The Jikei University School of Medicine Aoto Hospital, (2)Division of Diabetes and Endocrinology, Department of Internal Medicine, The Jikei University School of Medicine Aoto Hospital, (3)Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine Aoto Hospital, (4)Division of Diabetes and Endocrinology, Department of Internal Medicine, The Jikei University School of Medicine Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S454-S455, 2010.

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P4-5-1 Transcriptional repressor PLZF is differentially expressed in thyroid neoplasm, reflecting the impairment of follicular formation

Kazuhiko Matsuzawa(1), Shin-ichi Taniguchi(1), Shoichiro Izawa(1), Tsuyoshi Ohkura(1), Hiroko Ohkura(1), Kiyosuke Ishiguro(1), Akio Yoshida(1), Chiaki Shigemasa(1), Yumi Takiyama(2), Masakazu Haneda(2)
(1)Tottori University Faculty of Medicine, (2)Asahikawa School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S455-S455, 2010.

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P4-5-2 Nuclear retinoid receptor and retinoid X receptor subtypes distribution in human thyroid carcinomas

Julius Brtko(1), Dana Macejova(1), Slavomira Ondkova(1), Stefan Galbavy(2), Jan Podoba(2), Eva Takacsova(2), Juraj Kausitz(2)
(1)Institute of Experimental Endocrinology, Slovak Academy of Sciences, (2)Saint Elizabeth Institute of Oncology
ENDOCRINE JOURNAL 57 (suppl.2-2) S455-S455, 2010.

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P4-5-3 Serum thyrotropin is an independent risk predictor of overall but not micro-differentiated thyroid cancer

Haixia Guan, Yushu Li, Zhongyan Shan, Weiping Teng
Department of Endocrinology and Metabolism, First Affiliated Hospital of China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S455-S455, 2010.

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P4-5-4 Molecular targeting therapy with external radiation for intractable and poor-prognosis thyroid carcinoma

Atsushi Kumagai(1), Akira Ohtsuru(1), Toshiro Usa(2), Norisato Mitsutake(3), Shunichi Yamashita(1), (3)
(1)Takashi Nagai Memorial International Hibakusha Medical Center, Nagasaki University Hospital, (2)Department of Endocrinology and Metabolism, Nagasaki University Graduate School of Biomedical Sciences, (3)Department of Molecular Medicine, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, (4)Department of Molecular Medicine, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S455-S456, 2010.

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P4-5-5 Ten-year survival in thyroid papillary carcinoma with brain metastases

Luiz De Marco(1), Elizabete Miranda(1), Eduardo L.Padrao(2), Marta S.Sarquis(1)
(1)Faculdade de Medicine, Universidade Federal de Minas Gerais, (2)Nuclear Medicine, Hospital biocor
ENDOCRINE JOURNAL 57 (suppl.2-2) S456-S456, 2010.

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P4-5-6 Recombinant human thyrotropin in evaluating patients with differentiated thyroid carcinoma

Jan Podoba
St.Elizabeth Cancer Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S456-S456, 2010.

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P4-5-7 Relationship between the expression of glucose transporters and 18F-FDG uptake in papillary thyroid cancer patients

Yuji Hiromatsu(1), Hayato Kaida(2), Masatoshi Ishibashi(2), Seiji Kurata(2), Hirohito Umeno(3), Akihiko Kawahara(4), Masayoshi Kage(4), Satoshi Hattori(5)
(1)Division of Endocrinology and Metabolism, Department of Medicine, (2)Division of Nuclear Medicine, PET Center, and Department of Radiology, Kurume University School of Medicine, (3)Department of Otolaryngology, Oral and Maxillofacial Surgery, Kurume University School of Medicine, (4)Department of Pathology, Kurume University Hospital, (5)Biostatistics Center, Kurume University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S456-S456, 2010.

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P4-5-8 Video presenatation of surgical technique of sentinel lymph node biopsy in differentiated thyroid carcinoma using methylen blue dye

Radan R.Dzodic, Ivan Z.Markovic, Igor Djurisic, Marko Buta, Gordana Pupic, Zorka Milovanovic
Institute of oncology and radiology of Serbia, University of Belgrade
ENDOCRINE JOURNAL 57 (suppl.2-2) S456-S456, 2010.

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P4-6-1 Pattern of presentation and management outcomes of thyroid disorders

Anthonia O.Oghera
Department of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S457-S457, 2010.

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P4-6-2 A case of histologically diagnosed subacute thyroiditis with positive TSH receptor antibody and high thyroidal radioactive iodine uptake

Hiroshi Fukazawa(1), Masahiro Hata(2), Noriko Ohtani(3), Kanako Sakurai(1), Zenei Arihara(1), Hideto Motegi(1), Akio Mihara(1), Yoshinori Taeda(2), Tatsuya Fukumori(2), Ryou Ushijima(2), Katsumi Yoshida(4)
(1)Internal Medicine, Suifu Hospital, (2)Surgery, (3)Department of Pathology, (4)Division of Pathophysiology, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S457-S457, 2010.

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P4-6-4 Amiodarone-induced destructive thyrotoxicosis complicated by hypothyroidism after subacute de Quervain thyroiditis:Case report

Jiang Ju Ying(1), Chih-Yuan Wang(2)
(1)Division of Endocrinology and Metabolism, Department of Internal Medicine, Far Eastern Memorial Hospital, (2)Division of Endocrinology and Metabolism, Department of Internal Medicine, Far Eastern Memorial Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S457-S457, 2010.

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P4-6-5 Clinical characteristics of seven Japanese patients with amiodarone-induced thyroid dysfunction

Yoshiko Kanezaki, Keiko Miya, You Nakai, Eri Kondo, Yasumi Shintani
Division of Metabolism and Endocrinology, Tokushima Red Cross Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S457-S458, 2010.

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P4-6-6 To verify the thyroid disorders during early pregnancy:Screening or case-finding strategy

Zhongyan Shan, Weiwei Wang, Weiping Teng, Sen Wang, Jianxin Li, Jinyuan Mao
Department of Endocrinology and Metabolism, the First Affiliated Hospital, China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S458-S458, 2010.

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P4-6-7 Anti-cancer ability of β-elemene on IHH-4 and ASH-3 thyroid cancer cells in vitro and in vivo

Zhongyan Shan, Xiaoguang Shi, Yun Gao, Weiping Teng
Department of Endocrinology and Metabolism, the First Affiliated Hospital, China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S458-S458, 2010.

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P4-6-8 A linkage study of Graves disease in chromosome 5q31 region in Chinese multiplex families

Zhongyan Shan, Jia Li, Weiping Teng
Department of Endocrinology and Metabolism, the First Affiliated Hospital, China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S458-S458, 2010.

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P4-6-9 Could screening of thyropathies in pregnancy be effective?

Hana Sarapatkova(1), Yvona Hrckova(2)
(1)Salvus Medeco, (2)1st.Internal Clinic, Palacky university Olomouc
ENDOCRINE JOURNAL 57 (suppl.2-2) S458-S458, 2010.

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P4-7-1 Three cases of Graves' disease patients with depression successfully treated by antidepressant

Atsushi Fukao(1), Junta Takamasu(2), Naoyuki Tsujimoto(3), Mitsuru Ito(3), Sumihisa Kubota(3), Akira Miyauchi(3), Toshiaki Hanafusa(4)
(1)First Department of Nursing, Ainogakuin College, (2)Takamatsu Endocrine Clinic, (3)Kuma Hospital, (4)First Department of Internal Medicine, Osaka Medical College
ENDOCRINE JOURNAL 57 (suppl.2-2) S459-S459, 2010.

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P4-7-2 TSH-receptor autoimmunity and ophthalmopathy after radiolodine therapy

Kumiko Tsuboi, Natsuko Watanabe, Mayumi Ishikawa, Rena Yuasa, Ryo Iga, Natsumi Masai, Mariko Sue, Aya Yoshihara, Masahiko Miyagi, Kaoru Iso, Takamasa Ichijo, Naoki Hiroi, Koji Kuboki, Hajime Ueshiba, Gen Yoshino
Division of Diabetes, Metabolism and Endocrinology, Department of Medicine, Toho University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S459-S459, 2010.

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P4-7-3 Routine monitoring of liver functions in children with Graves' disease might be preventable propylthiouracil induced liver failure

Akinobu Minagawa(1), Jaeduk Yoshimura Noh(2), Yo Kunii(2), Koji Mukasa(2), Masako Matsumoto(2), Shotaro Sato(2), Miho Suzuki(2), Shigemitsu Yasuda(2), Natsuko Watanabe(2), Takuya Awata(1), Shigehiro Katayama(1), Koichi Ito(2), Kunihiko Ito(2)
(1)Department of Endocrinology and Diabetes, Saitama Medical University, (2)Ito Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S459-S459, 2010.

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P4-7-4 Sleep in thyrotoxicosis

Sridhar R.Gumpeny(1), Venkata P.Putcha(2), Lakshmi Gumpeny(3)
(1)Endocrine and Diabetes Centre, (2)Accostats Solution UK Ltd, (3)Kasturba Medical College
ENDOCRINE JOURNAL 57 (suppl.2-2) S459-S459, 2010.

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P4-7-5 Relationship of antiepileptic drug and thyroid hormone in a case of XYY syndrome with autoimmune polyendocrine syndrome(APS)

Hideyuki Iwama, Nao Ohkubo, Kyoko Higa, Michiko Ohshiro, Takeshi Tohma, Masaki Takara, Moritake Higa
Tomishiro Central Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S460-S460, 2010.

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P4-7-6 Iodine carrier proteins:The missing link between excess iodine and autoimmune thyroid disease

Ghollam-Reza Moshtaghi-Kashanian, Toraj Mirshekari, Mohammad Sokhtanlo, Lila Hassani Fard, Shahriar Dabiri
Physiology Research Center, and Biochemistry Department of Medical School, Kerman University of Medical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S460-S460, 2010.

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P4-7-7 Prevalence of thyroid autoantibodies and thyroid dysfunction in Japanese girls with Turner syndrome

Junko Ito(1), Susumu Yokoya(2)
(1)Department of Pediatric, Toranomon Hospital, (2)National Center for Child Health and Development
ENDOCRINE JOURNAL 57 (suppl.2-2) S460-S460, 2010.

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P4-7-8 Significance of color doppler sonography in diffuse toxic goiter

Elina Gasparyan(1), (2), Olga Goroshko(1), Anna Gasparyan(2)
(1)Medical Academy of Postgraduate Studies, Professor Medical Centre, (2)Goroshko Olga, 2, (3)Gasparyan A., 3
ENDOCRINE JOURNAL 57 (suppl.2-2) S460-S460, 2010.

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P4-8-1 Prevalence of thyroid incidentaloma detected during carotid duplex ultrasonography

Juan A.Hernandez Bayo(1), Monica Belinchon Sz.-Somoza(2), Victor Ferraz Jeronimo(2), Jose M.Hernandez Bayo(3)
(1)Endocrinology, General Hospital of La Palma, (2)Family Care, Primary Care of La Palma, (3)Radiology, Virgen del Puerto Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S460-S461, 2010.

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P4-8-2 Thyroid and parathyroid elastography in Japan

Shinichi Suzuki(1), Keiichi Nakano(1), Toshihiko Fukushima(1), Seiichi Takenoshita(1), Shuji Asahi(2), Kimiyoshi Shimanuki(2), Atsushi Muto(3)
(1)Department of Breast Endocrine Thyroid Surgery, Fukushima Medical University School of Medicine, (2)Department of Surgery, Aidu Chuo Hospital, (3)Department of Surgery, Fukushima Rosai Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S461-S461, 2010.

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P4-8-3 Clinical evaluation of thyroid elastography for the differential diagnosis of follicular tumors

Nobuhiro Fukunari, Masahide Nakano, Satoshi Sakaue, Takahiro Hayashi, Tomomi Yamazaki, Akio Nakamura, Kazushige Arai
Department of Surgery, Showa University, School of Medicine, Northern Yokohama Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S461-S461, 2010.

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P4-8-4 Fetal thyroid in 2-dimensional ultrasonography:Age-dependent and age-independent nomograms

Margaret M.Gietka-Czernel, Marzena Debska, Piotr Kretowicz, Romuald Debski, Wojciech Zgliczynski
Medical Center of Postgraduate Education
ENDOCRINE JOURNAL 57 (suppl.2-2) S461-S461, 2010.

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P4-8-5 Role of ultrasonography in outcome prediction in subclinical hypothyroid patients treated with levothyroxine

Dong Yeob Shin(1), Eun Jig Lee(1), Eun-Kyung Kim(2), Hyun Chul Lee(3)
(1)Endocrinology, Internal Medicine, Institute of Endocrine Research, Yonsei University College of Medicine, (2)Department of Radiology, Yonsei University College of Medicine, (3)Department of Internal Medicine, Yonsei University College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S461-S462, 2010.

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P4-8-6 Preoperative diagnosis of thyroid nodules by measuresing TFF3/LGALS3 mRNA(T/G)ratio:A clinical trial of fifty cases

Hiroya Yamada(1), (2), Toru Takano(1), (2), Minoru Kihara(3), Mitsuyoshi Hirokawa(3), Hiroshi Yoshida(3), Mikio Watanabe(2), Yoshinori Iwatani(2), Yoh Hidaka(1), Akira Miyauchi(3)
(1)Department of Laboratory Medicine, Osaka University Graduate School of Medicine, (2)Division of Health Sciences, Osaka University Graduate School of Medicine, (3)Kuma Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S462-S462, 2010.

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P4-8-7 The significance of fine needle aspiration biopsy(FNAB)in clinical practice

Gasparyan Elina(2), Goroshko Olga(1), Vorobyov Sergey(2)
(1)Medical Centre, Medical Academy of Postgraduate Studies, St.Petersburg, (2)Goroshko Olga, 2
ENDOCRINE JOURNAL 57 (suppl.2-2) S462-S462, 2010.

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P4-8-8 Identification of new molecular markers for thyroid malignancy

Valdis Pirags(1), (3), Kristine Ducena(1), Arturs Abols(2), Janis Vilmanis(3), Voldemars Bruns(3), Zenons Narbuts(3), Aija Line(2)
(1)Department of Internal Medicine, University of Latvia, (2)Latvian Centre for Biomedical Research and Studies, (3)Pauls Stradins Clinical University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S462-S462, 2010.

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P4-8-9 Usefulness of SPECT/CT as an adjunct to planar whole body I-131 scanning:Bone metastasis from follicular thyroid cancer

Nobuhiro Nakatake, Junichi Tajiri, Shuji Fukata
Tajiri Thyroid Clinic
ENDOCRINE JOURNAL 57 (suppl.2-2) S462-S463, 2010.

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P4-9-1 Increased XIAP and P2X7 receptor expression in thyroid papillary carcinoma and their associations with clinico-pathological features

Li-Qun Gu, Feng-Ying Li, Lin Zhao, Yun Liu, Guang Ning, Yong-Ju Zhao
Department of Endocrinology and Metabolic Diseases, Rui-jin Hospital, Shanghai Jiao-tong University School of Medicine, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases
ENDOCRINE JOURNAL 57 (suppl.2-2) S463-S463, 2010.

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P4-9-2 A proteosome inhibitor synergizes with histone deacetylase inhibitor-induced cell death and redifferentiation of thyroid carcinoma cells

Hiroki Shimura, Fumihiko Furuya, Miho Aoyagi, Kazuyasu Ohta, Toyoshi Endo, Tetsuro Kobayashi
The Third Department of Internal Medicine, University of Yamanashi
ENDOCRINE JOURNAL 57 (suppl.2-2) S463-S463, 2010.

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P4-9-3 Thyroid cancer in Ukraine:Incidence rate and trends after the Chernobyl accident

Mykola M.Fuzik(1), Anatoly Ye.Prysyazhnyuk(2), Zoya P.Fedorenko(3), Nataliya A.Gudzenko(2), Lyudmila O.Gulak(3), Nataliya K.Trotsyuk(2), Yevgeny L.Gorokh(3), Yoshisada Shibata(1), Vladimir A.Saenko(1), Shunichi Yamashita(1)
(1)Department of International Health and Radiation Research, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, (2)Research Center for Radiation Medicine of AMS of Ukraine, (3)National Cancer Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S463-S463, 2010.

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P4-9-4 Transition of antithyroid antibody by rituximab treatment for thyroid MALT lymphoma

Toshio Kahara(1), Noriko Iwaki(1), Hiroyasu Kaya(1), Toshiro Kurokawa(1), Takashi Yoshida(1), Akio Uchiyama(2), Kazuhide Ishikura(1), Rika Usuda(1)
(1)The Department of Internal Medicine, Toyama Prefectural Central Hospital, (2)The Department of Clinical Pathology, Toyama Prefectural Central Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S463-S464, 2010.

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P4-9-5 Potentiality of minimally invasive open approach with harmonic scalpel in the surgical treatment of thyroid carcinoma

Rumen N.Nenkov(1), Radoslav S.Radev(1), Kiril Hristozov(2)
(1)Clinic of Thoracic Surgery, Medical University of Varna, (2)Clinic of Endocrinology, Medical University of Varna
ENDOCRINE JOURNAL 57 (suppl.2-2) S464-S464, 2010.

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P4-9-6 Radioactive iodine therapy is effective in the treatment of cystic thyroid nodule

Leilani B.Mercado-Asis, Albert L.Chu, Aileen Y.Sia-Atanacio, Zarina G.Lorenzo
Section of Endocrinology and Metabolism, University of Santo Tomas Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S464-S464, 2010.

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P4-9-7 131 iodine therapy is effective in the management of diffuse and nodular non-toxic goiter

Leilani B.Mercado-Asis, Aileen Y.Sia-Atanacio, Albert L.Chu, Zarina G.Lorenzo, Stefanie W.Lim-Uy, Analyza M.Galia, Lucy Anne E.Mamba
Section of Endocrinology and Metabolism, University of Santa Tomas Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S464-S464, 2010.

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P4-9-8 Severe hyponatremia after postoperative radioiodine remnant ablation for incidentally detected papillary thyroid carcinoma in two elderly women:Case reports

Kyoung-Ah Kim, Jeong Seok Yeo
Department of Medicine, Dongguk University Ilsan Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S464-S464, 2010.

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P4-9-9 Metastatic esophageal adenocarcinoma of the thyroid

Oscar Castro(1), William Michalak(2)
(1)Butler Regional Endocrinology, (2)Butler Memorial Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S465-S465, 2010.

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P4-10-1 Graves' ophthalmopathy with non-thyroidal malignancy:A possible mechanism for induction of orbital lesions

Ai Yoshihara(1), (2), Osamu Isozaki(1), Yumiko Okubo(1), Saori Ishigaki(1), Risshu Inoue(3), Kazue Takano(1)
(1)Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, (2)Department of Medicine, Shinmatsudo Central General Hospital, (3)Olympia Eye Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S465-S465, 2010.

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P4-10-2 Influence of sera and TSH monoclonal antibodies from patients with Graves' disease/ophthalmopathy on growth and differentiation of 3T3-L1 preadipocytes

Takashi Hinata(1), Yasuhiro Watanabe(2), Koji Morita(1), Fumihiko Kimura(4), Takashi Akamizu(3), Yuji Tanaka(1)
(1)Division of Endocrinology & Metabolism, Department of Internal Medicine, National Defense Medial College, (2)Department of Pharmacology, National Defense Medical College, (3)Translational Research Center, Kyoto University Hospital, Kyoto University Graduate School of Medicine, (4)The Third Department of Internal Medicine, National Defense Medical College
ENDOCRINE JOURNAL 57 (suppl.2-2) S465-S465, 2010.

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P4-10-3 Peripheral blood mononuclear cells proliferation and apoptosis in Graves ophthalmopathy:What can be done?

Anastasiya E.Hlazkova, Irina R.Melnik, Larissa I.Danilova, Aleksey A.Romanovskiy
Belarussian Medical Academy of Post-Graduate Education
ENDOCRINE JOURNAL 57 (suppl.2-2) S465-S465, 2010.

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P4-10-4 The role of renin-angiotensin system in tissue inflammation of Graves' ophthalmopathy:Possible usefulness of antgiotensin receptor blockers

Osamu Isozaki(1), Saori Ishigaki(1), Ai Yoshihara(1), Yasuko Nozoe(1), Yoichi Inoue(2), Kazue Takano(1)
(1)Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, (2)Olympia Eye Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S466-S466, 2010.

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P4-10-5 A epidemiological study of the serum thyrotropin reference range and its influence factors in iodine sufficient areas

Zhongyan Shan, Chenyan Li, Weiping Teng
Department of Endocrinology and Metabolism, the First Affiliated Hospital, China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S466-S466, 2010.

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P4-10-6 An eight-year follow-up study of Graves disease in Chinese Han pedigrees

Zhongyan Shan, Xin Hou, Yushu Li, Wengping Teng
Department of Endocrinology and Metabolism, the First Affiliated Hospital, China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S466-S466, 2010.

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P4-10-7 The effects of selenium on iodine-induced thyroid cytotoxicity in vivo

Zhongyan Shan, Wei Chong, Weiping Teng
Department of Eodocrinology and Metabolism, the First Affiliated Hospital, China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S466-S466, 2010.

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P4-10-8 Dynamic changes of serum TSAb in patients with PPT:A 5-year follow-up study

Zhongyan Shan, Ling Shan, Weiping Teng
Department of Endocrinology and Metabolism, the First Affiliated Hospital, China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S466-S467, 2010.

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P4-11-1 The prevalence of polycystic thyroid disease in the hypothyroid patients with negative thyroid auto-antibodies

Sumihisa Kubota, Mako Fujiwara, Hanae Hagiwara, Naoyuki Tsujimoto, Kazuna Takata, Takumi Kudo, Eijun Nishihara, Mitsuru Ito, Nobuyuki Amino, Akira Miyauchi
Kuma Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S467-S467, 2010.

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P4-11-2 Analysis of TBX1 gene in patients with thyroid hemiagenesis

Marek Ruchala(1), Ewelina Szczepanek(1), Malgorzata Jaroniec(2), Witold Szaflarski(2), Lidia Kilinska(1), Maciej Zabel(2), Jerzy Sowinski(1)
(1)The Department of Endocrinology, Metabolism and Internal Medicine, University of Medical Sciences, (2)Department of Histology and Embryology, University of Medical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S467-S467, 2010.

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P4-11-3 High iodine concentration effects in TGFβ pathway related genes in RET/PTC3 activated thyroid follicular cell

Cesar S.Fuziwara(1), (2), Ana P.Z.P.Fiore(1), Edna T.Kimura(1)
(1)Department of Cellular and Developmental Biology, Institute of Biomedical Sciences, University of Sao Paulo, (2)Department of Molecular Medicine, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S467-S467, 2010.

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P4-11-4 Metformin inhibits HIF-1 alpha expression in human anaplastic thyroid cancer cells by suppressing mitochondrial respiration

Yumi Takiyama, Yukihiro Fujita, Masakazu Haneda
Department of Medicine, Asahikawa Medical College
ENDOCRINE JOURNAL 57 (suppl.2-2) S468-S468, 2010.

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P4-11-5 Thyroperoxidase immunostaining expression in the fine needle aspirated thyroid tumor cells

Wei Qu(1), Ling Jiang(2), Yi Bao(1), Yanme Zhang(3), Zhimin Liu(1)
(1)Department of Endocrinology, Changzheng Hospital, Second Millitrary Medical University, (2)Department of Endocrinology, Qilu Hospital, Shandong University, (3)XinTai people Hospital 271200
ENDOCRINE JOURNAL 57 (suppl.2-2) S468-S468, 2010.

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P4-11-6 Thyroid nodular pathology in patients with and without acromegaly

Larisa I.Danilova(1), Dmitri V.Raduk(1), Maksim L.Lushchik(1), Zanna L.Sretenskaya(1), Tatiana I.Rogounovitch(2), Yuri E.Demidchik(1), Shunichi Yamashita(2)
(1)Endocrinology department, Belarus medical academy of postgadute-education, (2)Department of Molecular Medicine, Nagasaki Graduate School of Biomedical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S468-S468, 2010.

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P4-11-7 131I accumulation in the inflammatory region of the lung in a woman with thyroid papillary carcinoma

Kanta Fujimoto, Yumiko Tahara, Shiho Takahara, Toshio Iwakura, Naoki Matsuoka, Hiromasa Kobayashi, Megumu Hino, Takashi Ishihara
Kobe City Medical Center General Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S468-S468, 2010.

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P4-11-8 Estimation of the effects of local drug injection on the benign thyroid tumor

Junjie Zou, Jiaoyang Zheng, Yi Bao, Wei Tang, Yongquan Shi, Zhimin Liu
Department of Endocrinology, Changzheng Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S469-S469, 2010.

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P4-11-9 Insular thyroid carcinoma in a Filipino:Case report and review of literature

Mark Anthony S.Sandoval, Elizabeth Paz-Pacheca
Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, Philippine General Hospital, University of the Philippines Manila
ENDOCRINE JOURNAL 57 (suppl.2-2) S469-S469, 2010.

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P4-12-1 Induction of germinal vesicle breakdown(GVBD)in frog(Euphlyctis cyanophlyctis)oocytes by metabolic hormone

Pancharatna A.Katti, Prasad A.Deshpande, Manjunath G.Ghodageri
Department of Zoology, Karnatak University
ENDOCRINE JOURNAL 57 (suppl.2-2) S469-S469, 2010.

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P4-12-2 Hihg total T3 levels in a euthyroid patient due to circulating T3 autoantibody

Gul Bahtiyar(1), Mark Leplattanier(1), Charles Ekanem(1), Olugofemi Ogunjana(1), Mariana Garcia Touza(2), Alan Sacerdote(1)
(1)Department of Medicine, Woodhull Medical Center, (2)SUNY Downstate Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S469-S469, 2010.

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P4-12-3 Significant improvement in thyroid replacement after switching to nocturnal thyroxine administration

Thomas Ulahannan, Kate Greenhalgh
Department of Endocrinology and Diabetes, Gloucestershire Royal hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S469-S470, 2010.

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P4-12-4 Subclnical hypothyroidism in patients with chronic kidney disease

Hiromichi suzuki, Tsutomu Inoue, Yusuke Watanabe, Tomohiro Kikuta
Department of Nephrology, Saitama Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S470-S470, 2010.

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P4-12-5 Relation between non-thyroidal illness syndrome and obstructive sleep apnea

Nujen Colak Bozkurt(1), Erman Cakal(1), Esra Bilgin(2), Evrim Cakir(1), Hikmet Firat(2), Tuncay Delibasi(1)
(1)The Endocrinology Department, Ankara Diskapi Yildirim Beyazit Education and Research Hospital, (2)The Sleep Department, Ankara Diskapi Yildirim Beyazit Education and Research Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S470-S470, 2010.

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P4-12-6 Thyroid function and cardiovascular risk factors in patients with autoimmune thyroiditis

Celestino Neves(1), Marta Alves(1), Miguel Pereira(1), Renata Ramalho(2), Carmo Palmares(2), Cristina Guimaraes(2), Davide Carvalho(1), Luis Delgado(2), Jose Luis Medina(1)
(1)Endocrinology Service, Sao Joao Hospital, Faculty of Medicine, University of Porto, (2)Immunology Service, Sao Joao Hospital, Faculty of Medicine, University of Porto
ENDOCRINE JOURNAL 57 (suppl.2-2) S470-S470, 2010.

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P4-12-7 Interrelations between insulin resistance, lipid profile, and inflammation in patients with autoimmune thyroiditis

Celestino Neves(1), Marta Alves(1), Miguel Pereira(1), Renata Ramalho(2), Carmo Palmares(2), Cristina Guimaraes(2), Joao P.Ramos(2), Davide Carvalho(1), Luis Delgado(2), Jose Luis Medina(1)
(1)Endocrinology Service, Sao Joao Hospital, Faculty of Medicine, University of Porto, (2)Immunology Service, Sao Joao Hospital, Faculty of Medicine, University of Porto
ENDOCRINE JOURNAL 57 (suppl.2-2) S470-S471, 2010.

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P4-12-8 Hydatidiform mole and hyperthyroidism

Marta Alves, Celestino Neves, Daniel Carvalho-Braga, Jose Luis Medina
Endocrinology Service, Sao Joao Hospital, EPE, Faculty at Medicine, University of Porto
ENDOCRINE JOURNAL 57 (suppl.2-2) S471-S471, 2010.

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P4-13-1 Iodine status of pregnant women from central Poland 10 years after introduction of iodine prophylaxis program

Margaret M.Gietka-Czernel(1), Marzena Debska(2), Piotr Kretowicz(2), Helena Jastrzebska(1), Agnieszka Kondracka(3), Hana Snochowska(1), Piotr Zdunowski(1), Mariusz Oltarzewski(4)
(1)Dept.of Endocrinology, Medical Center of Postgraduate Education, (2)Dept.of Obstetrics and Gynecology, Medical Center of Postgraduate Education, (3)Dept.of Internal Diseases and Endocrinology, Warsaw Medical University, (4)Institute of Mother and Child
ENDOCRINE JOURNAL 57 (suppl.2-2) S471-S471, 2010.

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P4-13-2 Comparison of daily dosage of levothyroxine between pregnant women with hypothyrodism due to radioactive iodine therapy and chronic lymphocytic thyroiditis

Xiaolan Lian(1), Yao Bai(1), Weixin Dai(1), Yunhua Xu(2), Zhisheng Guo(1)
(1)The Department of Endocrinology, PUMC hospital, CAMS and PUMC, (2)The Department of gynecology & obstetrics, PUMC hospital, CAMS and PUMC
ENDOCRINE JOURNAL 57 (suppl.2-2) S471-S471, 2010.

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P4-13-3 Effect of levo-thyroxine replacement on postprandial hyperlipidemia in patients with subclinical hypothyroidism

Takeshi Arishima(1), (2), Mitsuru Ito(3), Ichiro Sasaki(2), Tetsuya Hiraiwa(2), Nobuyuki Amino(3), Akira Miyauchi(3), Norio Kanatsuna(1), Sadaki Sakane(1), Keizo Furukawa(1), Akihisa Imagawa(2), Toshiaki Hanafusa(2)
(1)Internal Medicine, Hirakata City Hospital, (2)Department of Internal Medicine(I), Division of Internal Medicine, Osaka Medical College, (3)Kuma Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S472-S472, 2010.

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P4-13-4 Levothyroxine replacement therapy for primary hypothyroidism-not as simple as it appears:The University Malaya Medical Centre, Malaysian experience

Siew Pheng Chan, Alex T B Tan, Ananda Vijay, Soo San Lim, Pendek Rokiah
Endocrine Unit, Department of Medicine, University of Malaya Medical Centre
ENDOCRINE JOURNAL 57 (suppl.2-2) S472-S472, 2010.

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P4-13-5 No impact of dietary iodine restriction in short term development of hypothyroidism following fixed dose radioactive iodine therapy for Graves' disease

Jubbin J.Jacob(1), Charles Stephen(2), Regi Oommen(3), Nihal Thomas(4), Mandalam S.Seshadri(4)
(1)Endocrine & Diabetes Unit, Department of Medicine, Christian Medical College and Hospital, (2)Department of Clinical Biochemistry, Christian Medical College, (3)Department of Nuclear Medicine, Christian Medical College, (4)Department of Endocrinology, Diabetes and Metabolism, Christian Medical College
ENDOCRINE JOURNAL 57 (suppl.2-2) S472-S472, 2010.

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P4-13-6 Thyroid dysfunction related to tyrosine kinase inhibitors:Analysis of the cases with renal cell carcinoma of the Yamagata University Hospital

Makoto Daimon(1), Noriko Aoyama(2), Tomoyuki Kato(3), Shigeru Karasawa(1), Kiriko Wada(1), Wataru Kameda(1), Shinji Susa(1), Toshihide Oizumi(1), Yoshihiko Tomita(3), Takeo Kato(1)
(1)The Third Department of Internal Medicine, Yamagata University, (2)Department of Nursing, amagata University, (3)Department of Urology, Yamagata University
ENDOCRINE JOURNAL 57 (suppl.2-2) S472-S473, 2010.

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P4-13-7 First results of the LISA-Trial:Significant reduction of total nodule volume by non suppressive treatment with a combination of thyroxine and iodine

Martin Grussendorf(1), Renate Vaupel(2), Christoph Reiners(3), Ralf Paschke(4), Karl Wegscheider(5)
(1)Endokrinologie und Diabetologie im Zentrum, (2)Sanofi-Aventis, (3)Klinik fuer Nuklearmedizin, (4)Medizinishce Universitaetsklinik, (5)Institut fuer Epidemiologie und Biometrie
ENDOCRINE JOURNAL 57 (suppl.2-2) S473-S473, 2010.

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P4-13-8 Management of hypertension in thyroid disease:Results from the IMPERIAL study

Sanjay Kalra(1), Manas P Baruah(2), Navneet Agrawal(3), Tushar Bandgar(4), Farida Husein(5), Sandip Mitra(5)
(1)bharti Hospital, (2)Excel Hospital, (3)Medical College, (4)KEM Hospital, (5)USV
ENDOCRINE JOURNAL 57 (suppl.2-2) S473-S473, 2010.

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P4-13-9 Effects of dietary soy intake on maternal thyroid function and serum TPOAb level during early period of pregnancy

Jing Li, Zhongyan Shan, Weiping Teng, Weiwei Wang
Department of Endocrinology and Metabolism, the First Affiliated Hospital, China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S473-S473, 2010.

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P4-14-1 Etiologies and symptoms of thyrotoxicosis diagnosed in a primary care clinic

Hiroshi Saito, Rie Hirokawa, Manami Seyama, Noboru Saito, Kaoru Nomura
Department of General Medicine, Tokyo Women's Medical University(TWMU)
ENDOCRINE JOURNAL 57 (suppl.2-2) S473-S474, 2010.

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P4-14-2 A familiar case of Japanese patient with euthyroid hyperthyroxinemia due to familial dysalbuminemic hyperthyroxinemia

Keiko Suyama(1), Tomoaki Tanaka(1), Naobumi Ishikawa(3), Hiroshi Yoshimura(2), Kotaro Yokote(1), Ichiro Tatsuno(1)
(1)Department of Clinical Cell Biology and Medicine, Chiba University Graduate School of Medicine, (2)Ito Hospital, (3)Ishikawa Clinic
ENDOCRINE JOURNAL 57 (suppl.2-2) S474-S474, 2010.

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P4-14-3 Prospective evaluation of levothyroxine therapy for pregnant women with subclinical hypothyroidism in China

Zhongyan Shan, Xiaohui Yu, Weiping Teng, Chenyan Li, Jia Li, Yanyan Chen, Weiwei Wang, Yuanbin Li, Chenling Fan
Department of Endocrinology and Metabolism, the First Affiliated Hospital, China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S474-S474, 2010.

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P4-14-5 Effect of iodine restriction in subclinical hypothyroidism patients

Obin Kwon, Dong Yeob Shin, Eun Jig Lee
Division of Endocrionology, Department of Internal Medicine, Yonsei University College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S474-S474, 2010.

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P4-14-6 Increases of the Th1/Th2 cell ratio in severe Hashimoto's disease and in the proportion of Th17 cells in intractable Graves' disease

Mikio Watanabe, Takashi Nanba, Naoya Inoue, Yoshinori Iwatani
Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S474-S474, 2010.

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P4-14-7 Profiling of serum proteins in autoimmune thyroid disease by SELDI-TOF mass spectrometry

Junko Takagi(1), Mariko Hashizume(1), Tomoki Kanehira(1), Kazuhiro Yoshikawa(2), Kazuo Otake(1), Tsuyoshi Nogimori(3)
(1)The Department of Internal Medicine, Division of Endocrinology, Metabolism and Diabetes, Aichi Medical University School of Medicine, (2)Promoting Center for Clinical Research, Aichi Medical University School of Medicine, (3)Konankosei Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S475-S475, 2010.

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P4-14-8 The effect of maternal subclinical hypothyroidism during pregnancy on brain development in rat offspring

Zhongyan Shan, Dijie Liu, Weiping Teng, Xiaohui Yu, Yun Gao, Sen Wang
Department of Endocrinology and Metabolism, the First Affiliated Hospital, China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S475-S475, 2010.

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P4-14-9 Retrospective evaluation of intravenous methylpredonisolone pulse therapy in view of methylpredonisolone dosage in patients with Graves' ophthalmopathy

Hiroko Ohkura, Kazuhiko Matsuzawa, Shoichiro Izawa, Youhei Fujioka, Hideki Shiochi, Naoya Yamamoto, Keisuke Sumi, Hiroshi Kinoshita, Tsuyoshi Ohkura, Shin-ichi Taniguchi, Akio Yoshida, Chiaki Shigemasa
Tottori University Faculty of Medicine, Department of Multidisciplinary Internal Medicine, Division of Molecular Medicine and Therapeutics
ENDOCRINE JOURNAL 57 (suppl.2-2) S475-S475, 2010.

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P4-15-1 The role of glutamic or aspartic acid in position four of the epitope binding motif and TSH-R-ECD epitope selection in Graves' disease

Hidefumi Inaba(1), (2), William Martin(3), Matt Ardito(3), Anne De Groot(3), Leslie De Groot(2)
(1)Shinshu University, (2)University of Rhode Island, (3)Epivax.Inc
ENDOCRINE JOURNAL 57 (suppl.2-2) S475-S476, 2010.

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P4-15-2 Impaired CD4+CD25+ regulatory T cells mediated by dendritic cells polarization in patients with Graves disease

Shu Wang
Shanghai Institute of Endocrine and Metabolic Diseases, Rui Jin HosPital, Shanghai Jiaotong University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S476-S476, 2010.

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P4-15-3 Association between smoking and thyroid autoantibodies and thyroid function in a population based study

Yushu Li, Yushu Li, Xiaolan Gu, Xiaoguang Shi, Haixia Guan, Xiaochun Teng, Zhongyan Shan, Weiping Teng
Department of Endocrinology and Metabolism, the First Affiliated Hospital, China Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S476-S476, 2010.

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P4-15-4 Gitelman's syndrome and Graves' disease

Shuji Fukata(1), Akira Hishinuma(3), Mako Fujiwara(2), Nobuhiro Nakatake(1), Junichi Tajiri(1)
(1)Tajiri Thyroid Ckinic, (2)Kuma Hospital, (3)Department of Clinical Laboratory Medicine, Dokkyo University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S476-S476, 2010.

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P4-15-5 A case of huge bleeding thyroid cyst successfully treated with ethanol injection therapy

Hiroyuki Itoh(1), Yasuhiro Ohno(1), (2), Takaaki Ymauchi(1), Choogyong Park(1), Takahiro Higashimoto(1), Kaori Murata(1), Satomi Yamagata(1), Masanori Moriguchi(1), Yoshihsa Hiromine(1), Takeshi Harada(1), Katsumori Komaki(1), Shinsuke Noso(1), Yumiko Kawabata(1), Hiroshi Ikegami(1)
(1)Endocrinology, Metabolism and Diabetes, Kinki University School of Medicne, (2)Sakai Hospital, Kinki University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S476-S476, 2010.

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P4-15-6 Subacute thyroiditis after seasonal influenza vaccination(Influenza HA vaccine SEIKEN)

Fumiatsu Yakushiji(1), Kenji Ohnishi(2), Mutsuko Yasuda(1), Hiroshi Fujita(3), Taiichiro Kobayashi(2), Masako Shimojo(4), Kaoru Nagasawa(5), Hiroyuki Kinoshita(1)
(1)Department of Internal Medicine, Tokyo Metropolitan Bokutoh Hospital, (2)Department of Infectious Diseases, Tokyo Metropolitan Bokutoh Hospital, (3)Depaetment of Transfusion Medicine, Tokyo Metropolitan Bokutoh Hospital, (4)Deaparment of Internal Medicine, Kanagawa Prefectual Shiomidai Hosptital, (5)Deaparment of Metabolism and Endocrinology, Toranomon hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S477-S477, 2010.

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P4-15-7 Hypothyroidism due to Hashimoto disease following subacute thyroiditis

Ken-ichi Nemoto(1), Kyoko Takeda(2), Masaki Monden(1), Hiroko Izumo(1)
(1)Division of Endocrinology & Metabolism, Department of Internal Medicine, St.Luke's International Hospital, (2)Clinical Laboratory Department, St.Luke's International Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S477-S477, 2010.

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P4-15-8 Emergence of rheumatoid arthritis shortly after thymectomy for myasthenia gravis in a patient with Graves' disease-Kaleidoscope of autoimmunity

Yasuyoshi Takahashi, Toru Iizaka, Ryou Saiki, Kenji Iwaku, Fumiko Otsuka, Matsuo taniyama
Division of Endocrinology & Metabolism, Department of Internal Medicine, Showa University Fujigaoka Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S477-S477, 2010.

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P4-16-1 Type 2 iodothyronine deiodinase is expressed in human mesenteric and subcutaneous preadipocyte

Emiko Nomura, Nagaoki Toyoda, Azusa Harada, Kumiko Nishimura, Chizuko Ukita, Atsushi Kosaki, Toshiji Iwasaka, Mitsushige Nishikawa
The Second Department of Internal Medicine, Kansai Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S477-S477, 2010.

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P4-16-2 Type 2 iodothyronine deiodinase activity is highly expressed in the large goiter with Hashimoto's thyroiditis

Nagaoki Toyoda(1), Emiko Nomura(1), Mitsuru Ito(2), Azusa Harada(1), Kumiko Nishimura(1), Chizuko Ukita(1), Toshiji Iwasaka(1), Sumihisa Kubota(2), Akira Miyauchi(2), Mitsushige Nishikawa(1)
(1)The Second Department of Internal Medicine, Kansai Medical University, (2)Kuma Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S478-S478, 2010.

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P4-16-3 Genomic microdeletion of 6,675 nucleotides encompassing exon 28 and 29 of thyroglobulin(Tg)gene was found with a compound heterozygous occurrence of single nucleotide deletion 7890delT

Akira Hishinuma(1), Shuji Fukata(2), Narumi Ohmika(1), Noriko Hayama(1), Takashi Namatame(3), Tamio Ieiri(1)
(1)Department of Clinical Laboratory Medicine, Dokkyo Medical University, (2)Tajiri Clinic, (3)Institute of Medical Science, Dokkyo Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S478-S478, 2010.

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P4-16-4 Toll-like receptor activation fails to induce lymphocytic thyroiditis in nonobese diabetic mice

Kazuki Morohoshi(1), (2), Kouki Mori(1), Yoshinori Nakagawa(1), Saeko Hoshikawa(1), Hiroshi Ozaki(1), Sadayoshi Ito(1), Katsumi Yoshida(2)
(1)Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, (2)Department of Medical Technology, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S478-S478, 2010.

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P4-16-5 Indirect regulation of pancreatic proteins by thyroid hormone revealed by proteome analysis

Masamichi Oh-Ishi(1), Yoshio Kodera(1), (2), Sen-ichi Furudate(3), Mamoru Satoh(4), Tadakazu Maeda(1), (2)
(1)Department of Physics, Kitasato University School of Science, (2)Center for Disease Proteomics, Kitasato University School of Science, (3)Department of Laboratory Animal Science, Kitasato University School of Medicine, (4)Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University
ENDOCRINE JOURNAL 57 (suppl.2-2) S478-S478, 2010.

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P4-16-6 Lovastatin-induced differentiation of anaplastic thyroid cancer cells via flotillin-1 as a downstream mediator

Chih-Yuan Wang(1), Hao-Al Shui(2), Tien-Chun Chang(3)
(1)Division of Endocrine, Department of Internal Medicine, Far-Eastern Memorial Hospital, (2)Graduate Institute of Medicine Science, National Defence Medical Center, (3)Department of Internal Medicine, National Taiwan University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S478-S479, 2010.

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P4-16-7 Proteomics analysis in rosiglitazone-induced apoptosis of human anaplastic thyroid cancer cells

Chih-Yuan Wang(1), Hao-Al Shui(2), Tien-Chun Chang(3)
(1)Far-Eastern Memorial Hospital, (2)Graduate Institute of Medicine Science, National Defence Medical Center, (3)Department of Internal Medicine, Natioanl Taiwan University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S479-S479, 2010.

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P4-16-8 Anti-pendrin antibody, a novel autoantibody, highly detected in autoimmune thyroid diseases

Akio Yoshida(1), (2), (3), (4), (5), Kazuhiko Matsuzawa(2), Yuko Ohkura(2), Shoichiro Izawa(2), Keiichi Kamjyo(4), Shyuji Hukata(6), Jyunichi Tajiri(6), Eijun Nishihara(5), Akira Miyauchi(5), Shin-ichi Taniguchi(2), Chiaki Shigemasa(2), Koichi Suzuki(3)
(1)Department of Genetics and Regenerative Medicine, Tottori University Graduate School of Medicine, (2)Division of Molecular Medicine and Therapeutic, Department of Multidisciplinary Internal Medicine, Tottori University Faculty of Medicine, (3)National Institute of Infectious Diseases, (4)Kamijo Thyroid Research Institute, (5)Kuma Hospital, (6)Tajiri Clinic
ENDOCRINE JOURNAL 57 (suppl.2-2) S479-S479, 2010.

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P4-16-9 Effect of thyrotropin-releasing hormone on gene expression in the islet of Langerhans of the pancreas:Microarray hybridization analysis of TRH-deficient mouse

Nobuyuki Shibusawa, Jennifer Garay Guerrero, Kazuhiko Horiguchi, Yasuyo Nakajima, Koshi Hashimoto, Tetsurou Satoh, Masanobu Yamada, Masatomo Mori
Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S479-S479, 2010.

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P4-17-1 A unique nonsense mutation in the THRB1 gene, E457X, in a patient with resistance to thyroid hormone

Natallia Akulevich(1), Tatiana Rogounovitch(1), Vladimir Saenko(2), Valentina Drozd(3), Tatiana Leonova(3), Michiko Matsuse(1), Shunichi Yamashita(1), (2)
(1)Department of Molecular Medicine, Nagasaki University Graduate School of Biomedical Sciences, (2)Department of Inernational Health and Radiation Research, Nagasaki University Graduate School of Biomedical Sciences, (3)Department of Thyroid Disease Research, Belarusian Medical Academy for Postgraduate Education
ENDOCRINE JOURNAL 57 (suppl.2-2) S479-S480, 2010.

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P4-17-2 The effect of anti-thyroid drugs on sodium-iodide-symporter(NIS)expression in rat thyroid FRTL-5 cells

Mariko Sue(1), (2), Hanna Nakamura(2), (3), Akira Kawashima(1), Yuko Ishido(1), Huhehasi Wu(1), Takeshi Akama(1), Kazunari Tanigawa(1), Leonard D Kohn(3), Koichi Suzuki(1), (3)
(1)Laboratory of Moleculoar Diagnostics, Leoprosy Research Center, National Institute of infectious Diseases, (2)Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine(Omori), Toho University School of Medicine, (3)Cell Regulation Section, Metabolic Dseases Branch, NIDDK, National Institutes of Health
ENDOCRINE JOURNAL 57 (suppl.2-2) S480-S480, 2010.

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P4-17-3 μ-crystallin mRNA expression is positively controlled by 12-O-tetradecanoylphorbol-13-acetate through the AP-1 site in the promoter

Masahiro Takei, Satoru Suzuki
Department of Aging Medicine and Geriatrics, Shinshu University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S480-S480, 2010.

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P4-17-4 Protein kinase C(PKC)inhibited human type 2 iodothyronine deiodinase(D2)expression through proteasomal degradation

Takayuki Ogiwara(1), Tomoyuki Aoki(1), Katsuhiko Tsunekawa(1), Tadashi Morimura(1), Osamu Araki(1), Masatomo Mori(2), Masami Murakami(1)
(1)Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, (2)Department of Molecular Sciences, Gunma University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S480-S480, 2010.

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P4-17-5 An adenovirus carrying the FOX3a-TM suppresses the growth of human follicular thyroid carcinoma cells in vitro and in vivo

Zhenyu Hong(1), (2), Hyeon Jeong Lee(1), (2), Suk Kyoung Kim(1), (2), Eun Jig Lee(2), (3)
(1)Brain Korea 21 Project for Medical Science, Yonsei University, (2)Yonsei University College of Medicine, (3)Division of Endocrinology, Department of Internal Medicine, Graduate School of Medicine, Institute of Endocrinology, Yonsei University College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S480-S480, 2010.

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P4-17-6 An HDAC inhibitor, valproate improves the abnormalities in resistance to thyroid hormone

Koshi Hashimoto(1), Emi Ishida(1), Nobuyuki Shibusawa(1), Tetsurou Satoh(1), Masanobu Yamada(1), Fredric E Wondisford(2), Masatomo Mori(1)
(1)Department of Medicine and Molecular science, Gunma University Graduate School of Medicine, (2)Division of Metabolism, Johns Hopkins University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S481-S481, 2010.

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P4-17-7 Differential roles of 19S regulatory particles of 26S proteasome in the positive and negative gene regulation by thyroid hormone receptor

Tetsurou Satoh, Takahiro Ishizuka, Satoshi Yoshino, Takuya Tomaru, Yasuyo Nakajima, Akiko Katano, Nobuyuki Shibusawa, Atsushi Ozawa, Koshi Hashimoto, Masanobu Yamada, Masatomo Mori
Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S481-S481, 2010.

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P4-17-8 Low dose bromo-related compounds supress the thyroid hormone-induced brain development

Toshiharu Iwasaki, Kingsley Ibhazehiebo, Noriaki Shimokawa, Noriyuki Koibuchi
Department of Integrative Physiology, Gunma University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S481-S481, 2010.

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P5-1-1 Randomized, single-blind, placebo-controlled study of a novel calcilytic, JTT-305, in patients with postmenopausal osteoporosis

Seiji Fukumoto(1), Toshitaka Nakamura(2), Yoshiki Nishizawa(3), Mikio Hayashi(4), Toshio Matsumoto(5)
(1)Division of Nephrology & Endocrinology, Department of Meidcine, University of Tokyo Hospital, (2)Department of Orthopedic Surgery, University of Occupational and Environmental Health, (3)Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, (4)Biological/Pharmaceutical Research Laboratories, Japan Tobacco Inc.Central Pharmaceutical Research Institute, (5)Department of Medicine and Bioregulatory Sciences, University of Tokushima Graduate School of Medical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S481-S482, 2010.

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P5-1-2 MMP-dependent collagen breakdown is a major contributor to the increased bone markers in cardiovascular diseases:CHIBA(Coronary Heart Disease of Ischemia And Bone Association)study

Daisuke Inoue, Toshihiro Amaki, Yusuke Nakatsu, Kengo Ayabe, Jun-ichi Ohashi, Tadanao Higaki, Nobuyuki Tai, Fumitaka Nakamura, Ryo Okazaki
Third Department of Medicine, Teikyo University Chiba Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S482-S482, 2010.

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P5-1-3 Novel ultrasonic bone densitometry based on two longitudinal waves:Significant correlation with pQCT measurement values, and age-related changes in trabecular bone density, cortical thickness, and elastic modulus of trabecular bone in a normal Japanese population

Hanna Sai(1), Genzo Iguchi(1), (2), Takako Tobimatsu(1), (2), Kentaro Takahashi(1), (2), Takahiko Otani(3), Kaoru Horii(4), Isao Mano(4), Isamu Nagai(5), Hiroko Iio(6), Takuo Fujita(7), Kousei Yoh(8), Hisamitsu Baba(1), (2)
(1)Department of Biosignal Pathophysiology, Kobe University Graduate School of Medicine, (2)Medical Center for Student Health, Kobe University, (3)Faculty of Science and Engineering, Doshisha University, (4)OYO Electric Co., Ltd, (5)Kobe-kouyukai, Social Welfare Corporation, (6)Hyogo Health Service Association, (7)Calcium Research Institute, Katsuragi Hospital, (8)Department of Orthopedic Surgery, Hyogo College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S482-S482, 2010.

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P5-1-4 Prospective cohort study on osteoporosis utilizing hospital-clinic network and WEB registration(Fushimi Bone Study)

Sumire Ohtani(1), (2), Hikari Tsuji(3), Keiko Kitani(4), Keizou Furuke(5), Mariko Ooishi(6), Tomoko Suzuki(1), Tetsuya Tagami(1), Akira Shimatsu(1), Fushimi Bone study(1), Mitsuhide Naruse(1)
(1)Department of Endocrionology, Kyoto Medical Center, (2)Saitama National Hospital, (3)Tuji Clinic, (4)Kitani Clinic, (5)Furuke Clinic, (6)Ooisi Medical Clinic
ENDOCRINE JOURNAL 57 (suppl.2-2) S482-S482, 2010.

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P5-1-5 Comparison of the clinical characteristics of bisphosphonate-related osteonecrosis of the jaw with simple osteonecrosis of the jaw in osteoporotic patients

Yoon-Sok Chung(1), Min-Suk Lee(1), Eun-Kyung Kim(1), Tae-Ho Kim(1), Yong-Jun Choi(1), Hae-Jin Kim(1), Kwan Woo Lee(1), Kyu-Sung Kwak(2), Jeong-Keun Lee(3), Kyi-Beom Lee(4)
(1)Department of Endocrinology and Metabolism, Ajou University School of Medicine, (2)Department of Radiology, Ajou University School of Medicine, (3)Department of Dentistry, Ajou University School of Medicine, (4)Department of Pathology, Ajou University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S482-S483, 2010.

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P5-1-6 Possible association of combined vitamin D receptor and estrogen receptor and collagen type I alpha genotypes and low bone mineral density in girls during puberty

Anhelli Syrenicz(1), Elzbieta Sowinska-Przepiera(1), (2), Elzbieta Andrysiak-Mamos(1), Bartosz Kiedrowicz(1), Katarzyna Wachowiak-Ochmanska(2), Zbigniew Friebe(2)
(1)Department of Endocrinology, Metabolic and Internal Diseases, Pomeranian Medical University of Szczecin, (2)Department of Gynaecology, Chair of Perinatology and Gynaecology, Medical University of Poznan
ENDOCRINE JOURNAL 57 (suppl.2-2) S483-S483, 2010.

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P5-1-7 The effect of alendronate treatment on glucocorticoid induced osteoporosis in children

Hiroyuki Tanaka
Department of Pediatrics, Okayama Saiseikai General Hospital, Working Group for Secondary Osteoporosis in Childhood
ENDOCRINE JOURNAL 57 (suppl.2-2) S483-S483, 2010.

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P5-1-8 The relationship between serum serotonin levels and BMD in Chinese women

Lin Zhao, Min jia Zhang, Feng-ying Li, Lian-zhen Zhang, Wei-qin Wang, Guang Ning, Jian-min Liu
Shanghai Institute of Endocrine and Metabolic Diseases, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S483-S483, 2010.

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P5-2-1 Coexisting pheochromocytoma in a patient with oncogenic osteomalacia

Yasato Komatsu, Hideki Chusho, Yuji Hataya
Department of Endocrinology, Kyoto City Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S483-S483, 2010.

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P5-2-2 A case of tumor induced osteomalacia complicated with kidney stones after treated with calcitriol

Kiichiro Higashi(3), Satoko Hanatani(1), Shoko Kodama(1), Takeshi Takahashi(1), Tetsushi Toyonaga(1), Noriaki Adaniya(2), kazutoshi Nomura(3), Hidetaka I(4)
(1)Department of Diabetes and Endocrinology, National Hospital Organization, Kumamoto Medical Center, (2)The Self-Defence Forces Kumamoto Hospital, (3)Department of orthopedics, Naional Hospital Organization, Kumamoto National Hospital, (4)Kumamoto Urology Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S484-S484, 2010.

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P5-2-3 Primary versus tertiary hyperparathyroidism:A 68-year old female presenting with pathologic fracture and chronic kidney disease

Gregory Joseph Ryan A.Ardena, Hallert C.Ramos
Section of Endocrinology, Diabetes and Metabolism, University of the Philippines-Philippine General Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S484-S484, 2010.

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P5-2-4 Severe osteoporosis secondary to idiopathic hypogonadotrophic hypogonadism(IHH)in a 45-year old male

Gregory Joseph Ryan A.Ardena
Section of Endocrinology, Diabetes and Metabolism, University of the Philippines-Philippine General Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S484-S484, 2010.

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P5-2-5 Osteoporosis and partial lipodystrophy in two sibling patients with premature aging disease, mandibuloacral dysplasia

Yoko Miyoshi, Noriyuki Namba, Yasuhiro Hasegawa, Makiko Tachibana, Kazuhiko Bessho, Keiichi Ozono
Department of Pediatrics, Osaka University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S484-S484, 2010.

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P5-2-6 Premenopausal osteoporosis

K.J.Kim, K.M.Kim, H.S.Choi, Y.M.Rhee, E.Y.Park, D.Y.Shin, S.K.Lim
Endocrinology division, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S485-S485, 2010.

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P5-2-7 Incidence of symptomatic vertebral fractures during child-bearing age of women newly treated with high-dose glucocorticoid:Sub-analysis of Chiba-Shimoshizu rheumatic cohort

Tomohiko Yoshida(1), Takao Sugiyama(2), Sawako Suzuki(1), Hidekazu Nagano(1), Naoko Hashimoto(1), Takafumi Mayama(1), Keiko Suyama(1), Tomoaki Tanaka(1), Makoto Sueishi(2), Kotaro Yokote(1), Ichiro Tatsuno(1)
(1)Department of Clinical Cell Biology, Chiba University Graduate School of Medicine, (2)Department of Rheumatology, National Hospital Organization Shimoshizu National Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S485-S485, 2010.

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P5-2-8 Pitfall of bisphosphonate:Efficacy of bisphosphonate according to the year of use analyzed with QCT

Kyoung Min Kim(1), Kwang Joon Kim(1), Han Seok Choi(1), Jogeswar Gadi(1), Ajita Jami(2), Su Jin Park(2), Yumie Rhee(1), Sung-Kil Lim(1)
(1)Devision of Endocrinology, Internal Medicine, Yonsei University College of Medicine, (2)Brain Korea 21, Project for medical science, College of Medicine, Yonsei University
ENDOCRINE JOURNAL 57 (suppl.2-2) S485-S485, 2010.

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P5-3-1 The forkhead transcription factor Foxc2 stimulates osteoblastogenesis

Su Jin Park(1), Kyoung-Won Cho(2), Se Hwa Kim(3), Han Seok Choi(4), Kyoung Min Kim(4), Chun Ying Lian(1), Yumie Rhee(4), Han-Sung Jung(2), Sung-Kil Lim(4)
(1)Brain Korea 21 Project for Medical Science, College of Medicine, Yonsei University, (2)Division of Anatomy and Developmental Biology, Department of Oral Biology, College of Dentistry, Yonsei Center of Biotechnology, Yonsei University, (3)Division of Endocrinology, Department of Internal Medicine, Kwandong University College of Medicine, Myongi Hospital, (4)Division of Endocrinology and Endocrine Research Institute, Department of Internal Medicine, College of Medicine, Yonsei University
ENDOCRINE JOURNAL 57 (suppl.2-2) S485-S485, 2010.

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P5-3-2 Geranylgeranyl pyrophosphate(GGPP)and its synthase(GGPPS)promote proliferation but impair differentiation in mouse pre-osteoblastic MC3T3-E1 cells

Tomohiko Yoshida(1), (2), Paula H.Stern(2), Hidekazu Nagano(1), Naoko Hashimoto(1), Emi Imada(1), Keiko Suyama(1), Tomoaki Tanaka(1), Kotaro Yokote(1), Ichiro Tatsuno(1)
(1)Department of Clinical Cell Biology, Chiba University Graduate School of Medicine, (2)Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Feinberg School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S486-S486, 2010.

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P5-3-3 RAGE-ligand S100 indirectly promotes but directly inhibits osteoclastogenesis

Tomohiko Yoshida(1), (2), Ichiro Tatsuno(1), Hidekazu Nagano(1), Naoko Hashimoto(1), Emi Imada(1), Keiko Suyama(1), Tomoaki Tanaka(1), Kotaro Yokote(1), Paula H.Stern(2)
(1)Department of Clinical Cell Biology, Chiba University Graduate School of Medicine, (2)Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Feinberg School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S486-S486, 2010.

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P5-3-4 Menin interacts with β-catenin in osteoblast differentiation

Yoshifumi Inoue(1), Lucie Canaff(2), Geoffrey N Hendy(2), Itoko Hisa(1), Susumu Seino(1), (3), Hiroshi Kaji(1), (3)
(1)Division of Diabetes, Metabolism and Endocrinology, Kobe University, (2)Departments of Medicine, Physiology and Human Genetics, McGill University, (3)Division of Cellular and Molecular Medicine, Kobe University
ENDOCRINE JOURNAL 57 (suppl.2-2) S486-S486, 2010.

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P5-3-5 Myeloma-bone marrow stromal cell interaction enhances osteoclastogenesis and suppresses dendritic cell differentiation from monocytes

Masahiro Hiasa(1), (2), (3), Masahiro Abe(1), Itsuro Endo(1), Ayako Nakano(1), Syuji Ozaki(1), Eiji Tanaka(3), Kenzo Asaoka(2), Toshio Matsumoto(1)
(1)Department of Medicine and Bioregulatory Sciences, University of Tokushima Graduate School of Medicine, (2)Department of Biomaterials and Bioengineerings, University of Tokushima Graduate School of Oral Sciences, (3)Department of Orthodontics and Dentofacial Orthopedics, University of Tokushima Graduate School of Oral Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S486-S487, 2010.

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P5-3-6 Pycnogenol, an extract from French maritime pine, suppresses osteoclast differentiation

Shoichiro Ikuyama, Zhimeng Wang, Bin Fan
Medical Institute of Bioregulation, Kyushu University
ENDOCRINE JOURNAL 57 (suppl.2-2) S487-S487, 2010.

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P5-3-7 Adrenomedullin directly inhibits osteoclast differentiation in vitro through cyclic AMP pathway

Masako Miura(1), Kazumasa Nakao(2), Takuo Nambu(1), Noriaki Koyama(2), Kenji Osawa(2), Eri Kondo(1), Go Yamada(1), Toshihito Fujii(1), Masakatsu Sone(1), Naotetsu Kanamoto(1), Akihiro Yasoda(1), Naohisa Tamura(1), Hiroshi Arai(1), Kazuhisa Bessho(2), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Oral and Maxillofacial Surgery, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S487-S487, 2010.

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P5-3-8 Identification and functional analysis of a novel splicing variant of mouse RANK

Satomi Mukai(1), Riko Kitazawa(1), Junko Ishii(1), Takeshi Kondo(1), Akihiro Hakozaki(2), Keisuke Horiuchi(2), Kiyoshi Mori(1), Sohei Kitazawa(1)
(1)Dvision of Diagnostic Molecular Pathology, Kobe University Graduate School of Medicine, (2)Department of Orthopedic Surgery, Keio University, Shool of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S487-S487, 2010.

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P5-4-1 Vitamin D status in malaysia:Preliminary analysis of urban vs rural women

Siew Pheng Chan(1), Yee Yean Chew(1), Ananda Vijay(1), Alex T.B.Tan(1), Son San Lim(1), Abu Saad Hazizi(2), Pendek Rokiah(1)
(1)University of Malaya Medical Centre, (2)Institute of Gerontology, Universiti Putra Malaysia
ENDOCRINE JOURNAL 57 (suppl.2-2) S487-S488, 2010.

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P5-4-2 Role of loading calcitriol to control hypocalcemia after parathyroidectomy in chronic kidney disease

Niramitmahapanya Sathit(1), Thongkum Sunthomthepvarakul(1), Chaicham Deerochanawong(1), Veerasak Sarinnapakorn(1), Pornake Athipan(2)
(1)Department of Internal Medicine, Rajavithi Hospital, Faculty of medical school, Rangsit university, (2)Department of Otolaryngology-head and neck, Rajavithi Hospital, Faculty of medical school, Rangsit university
ENDOCRINE JOURNAL 57 (suppl.2-2) S488-S488, 2010.

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P5-4-3 The treatment and evolution of child osteoporosis, cases presentation

Otilla D.Marginean(1), Ioan D.Simedrea(1), Dana D.Bucuras(2), Adrian I.Craciun(1), Ioana G.Maris(1), Ecaterina V.Pavel(1)
(1)The First Pediatric Clinic of the University of Medecine and Pharmacy, (2)Endocrinology Departement of Dumitru Popescu Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S488-S488, 2010.

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P5-4-4 Bone mineral density in female survivors with childhood cancer

Nobuhiko Suganuma(1), Aya Yamauchi(1), Tomomi Kameda(1), Kanako Kiyokawa(1), Takashi Hamajima(2), Naoko Maeda(3), Keizo Horibe(3)
(1)Department of Human Health Sciences, Kyoto University Graduate School of Medicine, (2)Department of Endocrinology and Mteabolism, Aichi Children's Health and Medical Center, (3)Department of Pediatric, Nagoya Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S488-S488, 2010.

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P5-4-5 Comparison of preventive effects of bisphosphonate and raloxifene on glucocorticoid-induced osteoporosis in postmenopausal women

Ryoichi Takayanagi(1), Keizo Ohnaka(2), Hisaya Kawate(1), Masahiro Adachi(1), Masatoshi Nomura(1)
(1)Department of Medicine and Bioregulatory Science, Kyushu University, (2)Department of Geriatric Medicine, Kyushu University
ENDOCRINE JOURNAL 57 (suppl.2-2) S488-S489, 2010.

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P5-4-6 Approved indications for osteoporosis drugs in Japan-Review of applications using global clinical trial at PMDA

Yukie Sano, Akiko Ono, Kenichi Yanagi, Mari Ishida, Mai Hirano, Kayo Shinohara, Toshio Makie, Junichi Asano, Naoto Kato, Rumiko Hosoki, Masanobu Yamada, Masakazu Hirata
Pharmaceuticals and Medical Devices Agency
ENDOCRINE JOURNAL 57 (suppl.2-2) S489-S489, 2010.

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P5-4-7 Analysis of recently identified osteoporosis susceptibility genes in Han-Chinese Women

Min jia Zhang, Jian-min Liu, Lin Zhao, Bin Cui
Department of Endocrine and Metabolic Diseases, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S489-S489, 2010.

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P5-4-8 Octreotide therapies were unable to improve hypophosphatemia in oncogenic osteomalacia

Akia Ishii(1), Yasuo Imanishi(1), Keisuke Kobayashi(1), Jun Hashimoto(2), Takahumi Ueda(2), Akimitsu Miyauchi(3), Hiroshi Kaji(4), Yasato Komatsu(5), Masaaki Inaba(1), Yoshiki Nishizawa(1)
(1)Osaka City University Graduate School of Medicine, (2)Osaka University Graduate School of Medicine, (3)Calcium Research Institute, (4)Kobe University Graduate School of Medicine, (5)Kyoto City Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S489-S489, 2010.

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P5-5-1 Regulation of circulating fibroblast growth factor-23 by parathyroid hormone in patients with primary hyperparathyroidism

Masafumi Kurajoh, Yasuo Imanishi, Keisuke Kobayashi, Akira Ishii, Tomoki Nagata, Masaaki Inaba, Takami Miki, Yoshiki Nishizawa
Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S489-S489, 2010.

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P5-5-2 Unusual presentation of parathyroid adenoma

J Perez-Luis(1), J Lopez-Fernandez(1), O Rodriguez-Hernandez(1), MT Arce-Franco(1), (2)
(1)Endocrinology and Nutrition Department, Hospital Universitario de Canarias(HUC), (2)Pharmacology Department, Universidad de La Laguna
ENDOCRINE JOURNAL 57 (suppl.2-2) S489-S490, 2010.

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P5-5-3 Morphological changes of parathyroid hyperplasia in secondary hyperparathyroidism after calcium-mimetics(cinacalcet hydrochloride)administration

Kohji Mitani, Ayako Hoshiyama, Hajime Matsunaga, Harumi Daikoku, Masafumi Kitaoka
Division of Endocrinology and Metabolism, Showa General Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S490-S490, 2010.

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P5-5-4 Parathyroidectomy reduces cardiovascular mortality and symptoms in hemodialysis patients with severe hyperparathyroidism

Kazuhiro Nakao, Michio Suda, Kinya Matsubara, Masatomo Yashiro, Takaaki Yoshimasa
Kyoto city hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S490-S490, 2010.

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P5-5-5 Health-related quality of life in patients with mild primary hyperparathyroidism:A systematic overview

Takahiro Okamoto, Kiyomi Horiuchi, Masatoshi Iihara, Akiko Kawamata, Rumi Suzuki, Yusaku Yoshida, Akiko Sakamoto, Makoto Kammori
Department of Endocrine Surgery, Tokyo Womens Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S490-S490, 2010.

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P5-5-6 Asscociation of expression of parafibromin with sporadic parathyroid neoplasms

Ou Wang(1), Chunyan Wang(1), Xiaoping Xing(1), Quancai Cui(2), Xunwu Meng(1), Heng Guan(3), Weibo Xia(1), Mei Li(1), Yan Jiang(1), Guiyan Han(1)
(1)Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, (2)Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, (3)Department of Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science
ENDOCRINE JOURNAL 57 (suppl.2-2) S490-S491, 2010.

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P5-5-7 Symptomatic primary hyperparathyroidism associated with ectopic parathyroid glands

Marta Alves, Celestino Neves, Daniel Carvalho-Braga, Jose Luis Medina
Endocrinology Service, Sao Joao Hospital, EPE, Faculty of Medicine, University of Porto
ENDOCRINE JOURNAL 57 (suppl.2-2) S491-S491, 2010.

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P5-5-8 Cinacalcet treatment significantly deceases parathyroid gland volume in hemodialysis patients with secondary hyperparathyroidism

Eiji Ishimura(1), Mitsuru Ichii(2), Senji Okuno(3), Masaaki Inaba(2), Yoshiki Nishizawa(2)
(1)Department of Nephrology, Osaka City University Graduate School of Medicine, (2)Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, (3)Shirasagi Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S491-S491, 2010.

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P5-6-1 Involvement of pituitary hormones in bone metabolism in hypogonadism female patients with pituitary diseases

Yasuhiro Takeuchi(1), (3), Akira Takeshita(1), (3), Manabu Taguchi(1), Nobuaki Ito(1), Megumi Miyakawa(1), Kosuke Uchida(1), Kenichi Oyama(2), Shozo Yamada(2), (3)
(1)Toranomon Hospital Endocrine Center, (2)Department of Hypothalamus and Pituitary Surgery, Toranomon Hospital, (3)Okinaka Memorial Institute for Medical Research
ENDOCRINE JOURNAL 57 (suppl.2-2) S491-S491, 2010.

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P5-6-2 A possible involvement of TSH in human bone metabolism in patients with TSH producing pituitary adenoma is independent of thyroid hormone

Nobuaki Ito(1), Yuichiro Shimizu(1), Akira Takeshita(1), (3), Megumi Miyakawa(1), Kenichi Oyama(2), Shozo Yamada(2), (3), Yasuhiro Takeuchi(1), (3)
(1)Endocrine Center, Toranomon Hospital, (2)Department of Hypothalamus-Pituitary Surgery, Toranomon Hospital, (3)Okinaka Memorial Institute for Medical Research
ENDOCRINE JOURNAL 57 (suppl.2-2) S491-S492, 2010.

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P5-6-3 Adult-onset hypophosphatemic rickets:a case report

Ieva Ruza, Guna Krumina, Aivars Galvins
Department of Endocrinology, Gailezers clinics, Riga Eastern University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S492-S492, 2010.

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P5-6-4 A case of tumor induced osteomalacia that was initially masked by vitamin D deficiency

Lilian S-T Yeh(1), Huan-Sheng Lin(2), Shyang-Rong Shih(2), Keh-Sung Tsai(2), Tien-Shang Huang(2)
(1)Division of Endocrinology and Metabolism, department of Internal Medicine, Far Eastern Memorial Hospital, (2)Division of Endocrinology and Metabolism, department of Internal Medicine, National Taiwan University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S492-S492, 2010.

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P5-6-5 Hypophosphatemic osteomalacia as a long-term complication after liver transplantation

Hisaya Kawate(1), Tetsuhiro Watanabe(1), Masatoshi Nomura(1), Masaki Katoh(1), Ichiro Abe(1), Ryuichi Sakamoto(1), Toru Ikegami(2), Yuji Soejima(2), Akinobu Taketomi(2), Yoshihiko Maehara(2), Ryoichi Takayanagi(1)
(1)Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, (2)Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University
ENDOCRINE JOURNAL 57 (suppl.2-2) S492-S492, 2010.

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P5-6-6 A case of gastrointestinal amyloidosis showing persistent hypocalcemia due to malabsorption of magnesium

Tomohisa Yamashita, Marenao Tanaka, Hideaki Yoshida, Hiromichi Murase, Satoshi Yamamoto, Yusuke Okazaki, Norihito Moniwa, Nobuhiko Togashi, Masaya Hyakukoku, Masato Furuhashi, Kazuaki Shimamoto
The Second Department of Internal Medicine, Sapporo Medical University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S492-S493, 2010.

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P5-6-7 A case of hepatitis C-associated osteosclerosis with chronic cholecystitis

Yuji Hataya(1), Yorihide Fukuda(1), Hideki Chusho(1), Yasato Komatsu(1), Taisuke Morimoto(2)
(1)Department of Endocrinology, Kyoto City Hospital, (2)Department of Surgery, Kyoto City Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S493-S493, 2010.

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P5-6-8 Metastatic breast carcinoma with diffuse osteosclerosis:a case report

Huan-Sheng Lin, Tien-Shang Huang, Keh-Sung Tsai
Division of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S493-S493, 2010.

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P5-7-1 Pseudohypoparathyroidism type 1 with Addison's disease

Santosh K Chaubey(1), Yong M Tan(1), Emershia N Suthaharan(1), (2), Kunwarjit S Sangla(1), (2)
(1)Department of Endocrinology and Diabetes, The Townsville Hospital, (2)James Cook University
ENDOCRINE JOURNAL 57 (suppl.2-2) S493-S493, 2010.

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P5-7-2 Hyperphosphatemia induced by high phosphate-adenine diet progresses nephrotic syndrome in type III Na-dependent phosphate transporter over-expressing rats

Sahoko Sekiguchi, Megumi Shibata, Shougo Asano, Yasumasa Yoshino, Atsushi Yokoyama, Hiroaki Kakizawa, Nobuki Hayakawa, Naohisa Oda, Atsushi Suzuki, Mitsuyasu Itoh
The Department of Endocrinology, Fujita Health University Toyoake
ENDOCRINE JOURNAL 57 (suppl.2-2) S493-S494, 2010.

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P5-7-3 A pregnant patient with Gitelman syndrome showed tetraplegia due to severe hypokalemia and suffered from pulmonary thrombolisim during treatment

Chie Aoki(1), Kunihiro Suzuki(1), Takashi Namatame(2), Ayuko Nakano(1), Atsuko Tomizawa(1), Hiroyuki Kase(1), Yoshiyuki Hattori(1), Kikuo Kasai(1)
(1)Department of Endocrinology and Metabolism, Dokkyo University School of Medicine, (2)Department of Laboratory Medicine, Dokkyo University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S494-S494, 2010.

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P5-7-4 Mutation screening of epithelial sodium chanel gene with two patients clinically diagnosed as Liddle's syndrome

Haoming Tian(1), Jinyu Shi(1), Yan Ren(1), Xiang Chen(2)
(1)Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, (2)Department of Laboratory Medicine, West China Hospital of Sichuan University
ENDOCRINE JOURNAL 57 (suppl.2-2) S494-S494, 2010.

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P5-7-5 Significance of processed FGF23 fragments

Yuichiro Shimizu, Tasuku Saito, Hisanori Suzuki, Seiji Fukumoto, Toshiro Fujita
Division of Nephrology and Endocrinology, Department of Internal Medicine, University of Tokyo Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S494-S494, 2010.

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P5-7-6 Signal transduction triggered by extracellular inorganic phosphate involves FGF receptor and influences the FGF23 signaling

Miwa Yamazaki(1), Keiichi Ozono(2), Tomoko Okada(1), Yasuhisa Ohata(1), (2), Kanako Tachikawa(1), Hiroki Kondou(1), Toshimi Michigami(1)
(1)Department of Bone and Mineral Research, Osaka Medical Center and Research Institute for Maternal and Child Health, (2)Department of Pediatrics, Osaka University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S494-S495, 2010.

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P5-7-7 Gene therapy for nephrogenic diabetes insipidus with virus-based vectors carrying aquaporin 2 gene

Taka-aki Kondo(1), Hiroshi Nagasaki(2), Hidetaka Suga(3), Makoto Inoue(4), Mamoru Hasegawa(4), Yutaka Oiso(1)
(1)Department of Endocrinology & Diabetes, Field of Internal Medicine, Nagoya University Graduate School of Medicine, (2)Department of Metabolic Medicine, Nagoya University School of Medicine, (3)Division of Human Stem Cell Technology, RIKEN Center for Developmental Biology, (4)DNAVEC Res Inc
ENDOCRINE JOURNAL 57 (suppl.2-2) S495-S495, 2010.

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P5-7-8 Development of tertiary hyperparathyroidism in patients with X-linked hypophosphatemic vitamin D resistant rickets:Contribution of high FGF23 level before treatment

Tomozumi Takatani(1), Tasuku Saitoh(2), Yutaka Nishii(3), Kanshi Minamaitani(4), Masanori Minagawa(1), Tadashi Nishioka(5), Toshiyuki Yasuda(6), Seiji Fukumoto(7), Yoichi Kohno(1)
(1)Department of Pediatrics, Graduate School of Medicine, Chiba University, (2)Division of Pediatrics, University of Tokyo Hospital, (3)Division of Nephrology and Endocrinology, Department of Medicine, Nagano Municipal Hospital, (4)Department of Pediatrics, Teikyo University Chiba Medical Center, (5)Nishioka Clinic, (6)Department of Pediatrics, Chiba Medical Center, (7)Division of Nephrology & Endocrinology, Department of Medicine, University of Tokyo Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S495-S495, 2010.

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P5-8-1 Disease-related risk for symptomatic vertebral fracture during high-dose glucocorticoid treatment in female patients with collage vascular diseases:Subanalysis of Chiba-Shimoshizu rheumatic cohort

Ichiro Tatsuno(1), (2), Tomohiko Yoshida(1), (2), Sawako Suzuki(1), (2), Hidekazu Nagano(1), (2), Naoko Hashimoto(1), (2), Takafumi Mayama(1), (2), Keiko Suyama(1), (2), Tomoaki Tanaka(1), (2), Makoto Sueishi(3), Kotaro Yokote(1), (2), Takao Sugiyama(3)
(1)Department of Clinical Cell Biology, Chiba University Graduate School of Medicine, (2)Department of Clinical Endocrinology and Metabolism, Chiba University Hospital, (3)Department of Rheumatology, National Hospital Organization Shimoshizu National Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S495-S495, 2010.

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P5-8-2 Incidence and risk factors of symptomatic vertebral fractures in men newly treated with high-dose glucocorticoid:Sub-analysis of Chiba-Shimoshizu rheumatic cohort

Ichiro Tatsuno(1), (2), Sawako Suzuki(1), (2), Tomohiko Yoshida(1), (2), Hidekazu Nagano(1), (2), Naoko Hashimoto(1), (2), Takafumi Mayama(1), (2), Keiko Suyama(1), (2), Tomoaki Tanaka(1), (2), Makoto Sueishi(3), Kotaro Yokote(1), (2), Takao Sugiyama(3)
(1)Department of Clinical Cell Biology, Chiba University Graduate School of Medicine, (2)Department of Clinical Endocrinology and Metabolism, Chiba University Hospital, (3)Department of Rheumatology, National Hospital Organization Shimoshizu National Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S495-S496, 2010.

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P5-8-3 Investigation of bone metabolism in junior primary school students

Violetta Csakvary(1), Erzsebet Toldy(2), (4), Tamas Puskas(3), Gyorgy Oroszlan(1), Gabor L.Kovacs(4), (5)
(1)Department of Pediatry, Markusovszky Teaching Hospital, (2)Central Laboratory, Markusovszky Teaching Hospital, (3)Department of Radiology, Markusovszky Teaching Hospital, (4)Institute of Diagnostic and Management, University of Pecs, (5)Institute of Laboratory Medicine, University of Pecs
ENDOCRINE JOURNAL 57 (suppl.2-2) S496-S496, 2010.

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P5-8-4 Prevalence and risk factors of osteoporosis in the province of Chungju, Korea:A population-based study

Eunhee Jang(1), (3), Guilsun Kim(3), Seong-Su Lee(3), Ki-hyun Baek(1), (3), Ki-Hyun Baek(1), (3), Ki-Won Oh(2), Je-Ho Han(3), Hye-Soo Kim(3), Ho-Young Son(3), Moo-Il Kang(3)
(1)Department of Endocrinology and Metabolism, Yeoido St.Mary Hospital, (2)Department of Endocrinology and Metabolism, Kangbuk Samsung Hospital, Sungkyunkwan University, (3)Department of Endocrinology and Metabolism, The Catholic University of Korea
ENDOCRINE JOURNAL 57 (suppl.2-2) S496-S496, 2010.

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P5-8-5 Predictors of bone mineral density in type 1 diabetic men

Volha V.Zhukouskaya(1), Alla P.Shepelkevich(1), Jury V.Tolkachev(2)
(1)Internal Disease Chair 1, Belarusian State Medial University, (2)Republic Clinical Hospital of Medical Rehabilitation
ENDOCRINE JOURNAL 57 (suppl.2-2) S496-S496, 2010.

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P5-8-6 Etidronate prevents vascular calcification and improves bone mineral density in patients with chronic dialysis

Yosuke Okada, Osamu Hashimoto, Hiroko MOri, Yoshiya Tanaka
The First Department of Internal Medicine, University of Occupational and Environmental Health Japan
ENDOCRINE JOURNAL 57 (suppl.2-2) S496-S497, 2010.

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P5-8-7 Effects of raloxifene on bone metabolism and lipid profile in postmenopausal women with type 2 diabetes mellitus

Mori Hiroko, Okada Yosuke, Tanaka Yoshiya
The First Department of internal medicine, School of Medicine University of Occupational and Environmental Health
ENDOCRINE JOURNAL 57 (suppl.2-2) S497-S497, 2010.

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P5-8-8 A case of DiGeorge syndrome simulating a polyglandular autoimmune type 1 syndrome

Marcos Lahera Vargas, Carmen Alameda Hernando, Cesar Varela da Costa
Department of Endocrinology, Hospital Infanta Sofia
ENDOCRINE JOURNAL 57 (suppl.2-2) S497-S497, 2010.

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P5-9-1 Hyuganatsu orange(citrus tamurana)prevents osteoporosis in ovariectomized rats

Mastoshi Yamaguchi, Rurko Maruyama, Tsuyomu Ikenoue
Department of Obstetrics and Gynecology, University of Miyazaki
ENDOCRINE JOURNAL 57 (suppl.2-2) S497-S497, 2010.

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P5-9-2 The effect of raloxifene on bone, glucose and lipid metabolisms in postmenopausal asthmatic women treated with inhaled corticosteroids

Michio Otsuki(1), Akihiko Miyatake(2), Kimie Fijita(3), Tetsuhiro Kitamura(1), Soji Kasayama(4), Iichiro Shimomura(1)
(1)Department of Metabolic Medicine, Osaka University Graduate School of Medicine, (2)Miyatake Asthma Clinic, (3)School of Human Nursing, University of Shiga Prefecture, (4)Department of Medicine, Nissay Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S497-S498, 2010.

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P5-9-3 Loss of bone mass due to androgen-deprivation therapy in patients with prostate cancer in comparison with those having benign prostate hyperplasia

Kohei Hashimoto(1), Ko Kobayashi(1), Toshiaki Tanaka(1), Shin-ichi Hisasue(1), Toshihiro Maeda(1), Naoki Itoh(2), Naoya Masumori(1), Taiji Tsukamoto(1)
(1)Department of Urology, Sapporo Medical University School of Medicine, (2)Department of Urology, NTT East Sapporo Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S498-S498, 2010.

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P5-9-4 Osteoporosis in patients with low-activity rheumatoid arthritis-Preferential reduction of bone mineral density at the femur reflects impairment of physical activity

Hitoshi Goto, Shigeru Sugiguchi, Shinsuke Yamada, Keiji Okamoto, Yasuo Imanishi, Masaaki Inaba, Yoshiki Nishizawa
Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S498-S498, 2010.

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P5-9-5 Hypercalcaemia with protracted course of acute pancreatitis

Matej Zavrsnik
Endocrinological department, Internal Medicine, Clinical Center Maribor
ENDOCRINE JOURNAL 57 (suppl.2-2) S498-S498, 2010.

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P5-9-6 A case of primary hyperparathyroidism with classic and severe skeletal involvement:A thing of the past?

Mark Anthony S.Sandoval, Elizabeth Paz-Pacheco
Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, Philippine General Hospital, University of the Philippines Manila
ENDOCRINE JOURNAL 57 (suppl.2-2) S498-S499, 2010.

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P5-9-7 A puzzling case of nephrolithiasis, hypercalcemia, secondary amenorrhea, gross skeletal deformities and short stature hypercalcemia from genitourinary tuberculosis in a female with hereditary multiple exostoses:A case report

Mark Anthony S.Sandoval, Frances Lina C.Lantion-Ang
Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, Philippine General Hospital, University of the Philippines Manila
ENDOCRINE JOURNAL 57 (suppl.2-2) S499-S499, 2010.

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P5-10-1 Significance of measurement of FGF23 in the management of patients with tumor-induced osteomalacia(TIO)

Yuichiro Shimizu, Nobuaki Ito, Hisanori Suzuki, Takaaki Okamoto, Michiko Hori, Seiji Fukumoto, Toshiro Fujita
Division of Nephrology and Endocrinology, Department of Internal Medicine, University of Tokyo Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S499-S499, 2010.

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P5-10-2 Effects of steroids on functional interaction between TNF-α and BMP-2 in osteoblast differentiation

Yoshinori Matsumoto, Fumio Otsuka, Tomoyuki Mukai, Mariko Takano, Ryutaro Yamanaka, Misuzu Yamashita, Masaya Suzuki, Jiro Suzuki, Tomoko Miyoshi, Kenichi Inagaki, Hirofumi Makino
Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S499-S499, 2010.

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P5-10-3 Interferon-gamma inhibits the differentiation of osteoblasts by attenuating Wnt signaling

Masakazu Terauchi(1), Kei Sakamoto(2), Akira Yamaguchi(2), Toshiro Kubota(1)
(1)Department of Obstetrics and Gynecology, Tokyo Medical and Dental University, (2)Department of Oral Pathology, Tokyo Medical and Dental University
ENDOCRINE JOURNAL 57 (suppl.2-2) S499-S500, 2010.

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P5-10-4 Study on identification of N-glycoylation site in sclerostin protein and its role in Wnt signaling in vitro

Ajita Jami(1), Jogeswar Gadi(1), Su Jin Park(2), Han Seok Choi(1), Kyoung Min Kim(1), Sung-Kil Lim(1)
(1)Division of Endocrinology and Endocrine Research Institute, Department of Internal Medicine, Yonsei University College of Medicine, (2)Brain Korea 21 Project for medical sciences, Yonsei University College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S500-S500, 2010.

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P5-10-5 Klotho is expressed in placenta and its soluble form modulates canonical Wnt signaling in bone

Yasuhisa Ohata(1), (2), Miwa Yamazaki(1), Tomoko Okada(1), Hitomi Arahori(2), Makoto Fujiwara(2), Kouji Miura(2), Taichi Kitaoka(2), Noriyuki Namba(2), Haruhiko Hirai(2), Masahiro Nakayama(3), Keiichi Ozono(2), Toshimi Michigami(1)
(1)Bone and Mineral Research, Osaka Medical Center and Research Institute for Maternal and Child Health, (2)Department of Pediatrics, Osaka University Graduate School of Medicine, (3)Department of Clinical Laboratory Medicine and Anatomic Pathology, Osaka Medical Center and Research Institute for Maternal and Child Health
ENDOCRINE JOURNAL 57 (suppl.2-2) S500-S500, 2010.

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P5-10-6 Evaluation for the role of serum C-type natriuretic peptide in endochondral ossification

Toshihto Fujii, Yasato Komatsu, Akihiro Yasoda, Eri Kondo, Go Yamada, Takuo Nambu, Masako Miura, Masakatsu Sone, Naotetsu Kanamoto, Naohisa Tamura, Hiroshi Arai, Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S500-S500, 2010.

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P5-10-7 C-type natriuretic peptide(CNP)/guanyl cyclase-B(GC-B)system plays important roles in the development of craniofacial region

Kazumasa Nakao(1), Yasunori Okubo(1), Akihiro Yasoda(2), Noriaki Koyama(1), Kenji Osawa(1), Masako Miura(2), Kazuwa Nakao(2), Kazuhisa Bessho(1)
(1)Department of Oral and Maxillofacial Surgery, Graduate school of Medicine, Kyoto University, (2)Department of Medicine and Clinical Science, Graduate school of Medicine, Kyoto University
ENDOCRINE JOURNAL 57 (suppl.2-2) S500-S501, 2010.

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P6-1-1 Five cases of primary hyperparathyroidism diagnosed in our hospital recently

Tadasu Nagaoka(1), Masato Kiriyama(2), Sei-ichiro Kurita(1), Mitsuhiro Yoshimura(1), Yukio Nakamura(1), Atsuhiro Kawashima(3), Yutaka Noto(1), Yasuhiko Kojima(2)
(1)Department of Internal Medicine, Kanazawa Medical Center, (2)Department of Surgery, Kanazawa Medical Center, (3)Department of pathology, Kanazawa medical center
ENDOCRINE JOURNAL 57 (suppl.2-2) S501-S501, 2010.

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P6-1-2 Usefulness of minimally invasive thyroid and parathyroid surgery based on 460 cases of experience

Kazuo Shimizu, Haruki Akasu, Takehito Igarashi, Sherif Zeiden, Ritsuko Okamura
Department of Surgery, Division of Endocrine Surgery, Nippon Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S501-S501, 2010.

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P6-1-3 Perspectives in pituitary surgery:Per-operative ACTH sampling

Paul PCA Menheere, Erwin Cornips, Jean-Pierre Sels
Department of Clinical Chemistry and Endocrinology, Maastricht University Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S501-S501, 2010.

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P6-1-4 Anterior interhemispheric approach for 100 tumors in and around the anterior third ventricle-Operative & hormonal results with long-term follow-up

Tomokatsu Hori(1), Masami Ono(2), Nobuhiro Miki(2), Takakazu Kawamata(1), Kosaku Amano(1)
(1)The Department of Neurosurgery, Tokyo Women's Medical University, (2)Deopartment of Endocrinology, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S501-S502, 2010.

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P6-1-5 Surgical approach of adrenal tumors in a serie of cases

Bogdan Stanescu(1), Corina Chirita(2), Mara Carsote(1), Cristina Corneci(2), Dan Hortopan(2), Anda Dumitrascu(2), Dumitru Ioachim(2), Cristina Ene(2), Marga Matei(2), Dana Terzea(1), (2), (3), Catalina Poiana(1), (2)
(1)Department of Endocrinology, Carol Davila University of Medicine and Pharmacy, (2)C.I Parhon National Institute of Endocrinology, (3)Babes Institute of Development and Research
ENDOCRINE JOURNAL 57 (suppl.2-2) S502-S502, 2010.

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P6-1-6 A case of insulinoma effectively controlled with octreotide acetate

Tomoko Kawanishi(1), Seiji Muro(2), Shogo Oki(2), Takeshi Usui(4), Akira Shimatsu(4), Yukio Osaki(3), Takuya Inomoto(5), Kiyoshi Mori(1), Hideki Yokoi(1), Masato Kasahara(1), Masashi Mukoyama(1), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Division of Endocrinology and Metabolism, Osaka Red Cross Hospital, (3)Division of Gastroenterology and Hepatology, Osaka Red Cross Hospital, (4)Division of Metabolic Research, Clinical Research Institute for Endocrine and Metabolic Diseases, National Hospital Organization Kyoto Medical Center, (5)Division of Surgery, Osaka Red Cross Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S502-S502, 2010.

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P6-1-7 Effects of electrolyte on heat-stress resistance in male mice

Wen Cao(1), (2), Nan Li(1), Chi Meng(1), Lingling Shen(1), Fangxiong Shi(1), Gen Watanabe(2), Kazuyoshi Taya(2)
(1)Laboratory of Animal Reproduction, College of Animal Science and Technology, Nanjing Agricultural University, (2)Divislon of Animal Life Science, Institute of Symbiotic Science and Technology(Laboratory of Veterinary Physiology, Department of Veterinary Medicine), Tokyo University of Agriculture and Technology
ENDOCRINE JOURNAL 57 (suppl.2-2) S502-S502, 2010.

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P7-1-1 Acromegaly with normal IGF-1 levels possibly due to poorly controlled diabetes mellitus

Zenei Arihara(1), Kanako Sakurai(1), Hiroshi Fukazawa(1), Shozo Yamada(2), Osamu Murakami(3), Kazuhiro Takahashi(4)
(1)Department of Endocrinology and Metabolism, Suifu Hospital, (2)Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital, (3)Division of Nephrology, Endocrinology and Vascular Medicine Tohoku University, School of Medicine, (4)Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S502-S503, 2010.

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P7-1-2 The presence of systemic complications in Chinese patients with acromegaly

Ronald C.Ma, Chun-ming Chan, Yun-sang Chan, Grace H.Ng, Noelle W.Ng, Stanley S.Yip, Gary K.Yu, Alice P.S.Kong, Wing-yee So, Chun-chung Chow
Department of Medicine and Therapeutics, Chinese University of Hong Kong
ENDOCRINE JOURNAL 57 (suppl.2-2) S503-S503, 2010.

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P7-1-3 "Nadir GH in OGTT" may be a more predictable marker of future GHD than "peak GH in insulin tolerance test" after surgical treatment of growth hormone producing adenoma

Wataru Kameda, Kaoru Takase, Wataru Kaino, Kyoko Tada, Shigeru Karasawa, Yumi Jimbu, Kiriko Wada, Shinji Susa, Toshihide Oizumi, Makoto Daimon
The Third Department of Internal Medicine, University of Yamagata
ENDOCRINE JOURNAL 57 (suppl.2-2) S503-S503, 2010.

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P7-1-4 The changes of body composition in patients with acromegaly after pituitary adenoma surgery

Qinyong Wu, Huijuan Zhu, Feng Gu, Hui Pan, Jie ying Deng
Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S503-S503, 2010.

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P7-1-5 The therapeutic outcomes of patients with acromegaly since 2000

Izumi Fukuda, Naomi Hiduka, Makiko Kurimoto, Junko Morita, Satoshi Tanaka, Yu Yamakado, Akira Sata, Kazue Takano
Depertment of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S503-S503, 2010.

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P7-1-6 Diagnostic and treatment difficulties in acromegaly report of a case

Zsuzsanna Valkusz(1), Sandor Magony(1), Eva Csajbok(1), Janos Gardi(1), Ildiko Kiss(2), Janos Julesz(1)
(1)The First Department of Internal Medicine, University of Szeged, (2)Euromedic Diagnostics Szeged
ENDOCRINE JOURNAL 57 (suppl.2-2) S504-S504, 2010.

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P7-1-7 Spontaneous remission of acromegaly with accompanying panhypopituitarism following pituitary apoplexy:A case report

Mehtap Cakir, Suleyman Ipekci
Division of Endocrinology and Metabolism, Selcuk University
ENDOCRINE JOURNAL 57 (suppl.2-2) S504-S504, 2010.

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P7-1-8 Non hodgkins lymphoma in a case of acromegaly a rare association

Mohd Ashraf Ganie(1), Sobia Nisar(2), Nasir Shamas(1)
(1)Endocrinology Sher-i-Kashmir Institute of Medical Sciences, (2)Department of Medicine SMHS Hospital Srinagar
ENDOCRINE JOURNAL 57 (suppl.2-2) S504-S504, 2010.

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P7-2-1 The folliculo-stellate cells owe the role of cell division in the anterior pituitary at the special state

Eisuke Sakuma, Hiroyuki Kato, Kazuo Ikeda
Department of Functional Anatomy Nagoya City University Graduate School of Medical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S504-S504, 2010.

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P7-2-2 Cloning of a Prop1-binding factor that regulates Pit-1 gene expression

Yasuhiko Okimura(1), Yuka Sugiyama(1), Daisuke Yamamoto(1), Hiromi Shibahara(1), Nobuko Ikeshita(1), Taiki Maki(1), Elizabeth-Henny Herningtyas(1), (2), Genzo Iguchi(2), Keiji Ilda(3), Yutaka Takahashi(2), Hidesuke Kaji(4), Kazuo Chihara(3)
(1)Department of Biophysics, Kobe University Graduate School of Health Science, (2)Division of Diabetes, Nutrition and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, (3)Department of Medicine, Hyogo Prefectural Kakogawa Hospital, (4)College of Nursing Art and Science, University of Hyogo
ENDOCRINE JOURNAL 57 (suppl.2-2) S505-S505, 2010.

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P7-2-3 A case of Septo-optic pituitary dysplasia syndrome with microcephaly

Hidenari Nomura, Takeshi Usui, Yusuke Sagae, Yoriko Sakene-Ueda, Satoko Shimazu, Kazutaka Nanba, Tamiko Tamanaha, Tetsuya Tagami, Mitsuhide Naruse, Akira Shimatsu
Department of Endocrinology and Metabolism, National Hospital Organization Kyoto Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S505-S505, 2010.

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P7-2-4 Developmental changes of neuromedin U and galanin-like peptide gene expressions in the rat pituitary:an analysis by in situ hybridization histochemistry

Kazuyasu Kubo, Yukiyo Yamamoto, Rinko Kawagoe, Motohide Gotoh, Mariko So, Shunsuke Araki, Koichi Kusuhara
Department of Pediatrics, School of Medicine, University of Occupational and Environmental Health
ENDOCRINE JOURNAL 57 (suppl.2-2) S505-S505, 2010.

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P7-2-5 Luteinizing hormone receptor knockout ameliorates amyloid burden in a mouse model of alzheimer's disease

Zhenmin Lei, Xian Li, Fangping Yuan, Ling Lin, Christine L.Cook, ChV Rao, Jing Lin
Department of Obstetrics, Gynecology and Women's Health, University of Louisville School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S505-S505, 2010.

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P7-2-6 Differentiation capacity of folliculo-stellate cells in the anterior pituitary gland

Marumi Osuna, Yukiko Sonobe, Kinji Inoue
Saitama University
ENDOCRINE JOURNAL 57 (suppl.2-2) S506-S506, 2010.

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P7-2-7 Development of vasopressin and oxytocin neurons are prevented by social isolation stress

Kenjiro Tanaka, Yoji Osako, Kazunari Yuri
Department of Neurobiology and Anatomy, Kochi Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S506-S506, 2010.

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P7-2-8 Chicken adenohypophysis originates from two different regions of the embryonic head ectoderm

Makiko inoue(1), Rui Wang(1), Hiroyasu Takagi(1), Takafumi Sakai(1), (2)
(1)Graduate School of Science and Engineering, Saitama University, (2)Saitama University Brain Science Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S506-S506, 2010.

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P7-3-1 Suppression of vasopressin synthesis delayed phenotype progression in a mouse model for familial neurohypophysial diabetes insipidus

Yoshiaki Morishita, Hiroshi Arima, Maiko Hiroi, Masayuki Hayashi, Yutaka Oiso
Department of Endocrinology and Diabetes, Field of Internal Medicine, Nagoya University
ENDOCRINE JOURNAL 57 (suppl.2-2) S506-S506, 2010.

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P7-3-2 Proteomic search for novel autoantigens in patient with lymphocytic infundibulo-neurohypophysitis

Shintaro Iwama(1), Yoshihisa Sugimura(1), Takuya Kato(2), Haruyuki Suzuki(1), Atsushi Enomoto(2), (3), Hiroshi Arima(1), Yutaka Oiso(1)
(1)Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, (2)Department of Pathology, Nagoya University Graduate School of Medicine, (3)Institute for Advanced Research, Nagoya University
ENDOCRINE JOURNAL 57 (suppl.2-2) S507-S507, 2010.

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P7-3-3 A pedigree of neurohypophyseal diabetes insipidus with AVP gene mutation

Tomoko Kawahara(1), Hayato Yamaguchi(1), Sachiko Takagi(1), Makoto Ujihara(1), Satoko Shimazu(2), Takeshi Usui(2)
(1)Department of Endocrinology and Metabolism National Hospital Organization Yokohama Medical Center, (2)Department of Endocrinology and Metabolism, National Hospital Organization Kyoto Medical Center, Clinical Research Institute National Hospital Organization Kyoto Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S507-S507, 2010.

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P7-3-4 Inflammatory cytokines from Rathke cleft cysts are possible inducers of secondary hypophysitis

Osamu Tachibana(1), Yasuo Sasagawa(1), Keiichiroh Torigoe(1), Shunsuke Shiraga(1), Kenji Yamamoto(1), Kazuya Okamoto(1), Takaaki Iida(1), Takuya Akai(1), Hideaki Iizuka(1), Atsushi Nakagawa(2), Daisuke Koya(2)
(1)Department of Neurosurgery, Kanazawa Medical University, (2)Division of Endocrinology and Metabolism
ENDOCRINE JOURNAL 57 (suppl.2-2) S507-S507, 2010.

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P7-3-5 Polyostotic fibrous dysplasia in a female with mccune-albright syndrome

Marbert T.Cardino
PGH
ENDOCRINE JOURNAL 57 (suppl.2-2) S507-S507, 2010.

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P7-3-6 Gestational diabetes insipidus

Marbert T.Cardino
PGH
ENDOCRINE JOURNAL 57 (suppl.2-2) S508-S508, 2010.

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P7-3-7 A case suspected IgG4-related hypophysitis with Tolosa-Hunt syndrome and bilateral carotid artery occlusion

Sumiko F.Kato(1), (3), Ichiro Fujisawa(2), Ikuko Hanaoka(1), Tetsuya Ueba(3)
(1)The Department of Endocrinology and Metabolism, Kishiwada City Hospital, (2)The Department of Radiology, Kishiwada City Hospital, (3)The Department of Neurosurgery, Kishiwada City Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S508-S508, 2010.

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P7-3-8 A case of lung adenocarcinoma metastatic to the pituitary gland causing central diabetes insipidus

Flora F.Ip, N Wah Cheung
Department of Diabetes & Endocrinology, Westmead Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S508-S508, 2010.

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P7-3-9 Fever, diabetes insipidus, and hypopituitarism due to an inflammation accompanied by the Rathkes cleft cyst:A case report

Keiji Iida(1), Masaaki Taniguchi(2), Yasuhisa Hino(1), Takeshi Ohara(1), Kazuo Chihara(1)
(1)Division of Diabetes and Endocrinology, Hyogo Prefectural Kakogawa Medical Center, (2)Department of Neurosurgery, Kobe University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S508-S508, 2010.

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P7-4-1 Long-term follow-up results of carbergoline treatment for giant male prolactinomas

Manabu Taguchi(1), Akira Takeshita(2), Yasuhiro Takeuchi(2), Shozo Yamada(2), Toshiro Fujita(1)
(1)Department of Nephrology and Endocrinology, University of Tokyo Hospital, (2)Endocrine center, Toranomon Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S508-S509, 2010.

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P7-4-2 Macroprolactinomas apparently cured after therapy with dopamine agonists

Mihail Coculescu(1), (2), Raluca Trifanescu(1), (2), Monica L Gheorghiu(1), (2), Nicoleta Baculescu(1), Andra Caragheorgheopol(2)
(1)Bucharest University School of Medicine, (2)National Institute of Endocrinology
ENDOCRINE JOURNAL 57 (suppl.2-2) S509-S509, 2010.

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P7-4-3 Cabergoline-induced pregnancy in infertile women with prolactinoma

Masami Ono, Nobuhiro Miki, Toshiro Seki, Rena Makino, Kazue Takano
Department of Medicine II, Institute of Clinical Endocrinology, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S509-S509, 2010.

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P7-4-4 Cabergoline treatment of infertility in women with macroprolactinoma

Nobuhiro Miki, Masami Ono, Toshiro Seki, Rena Makino, Kazue Takano
Department of Medicine II, Institute of Clinical Endocrinology, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S509-S509, 2010.

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P7-4-5 Giant prolactinomas:a retrospective study of clinical features, treatment and outcome

Belinda George, Ganapathi Bantwal, Vageesh Ayyar, R.Ananthraman, Madhuri Patil, Rohini Chandra
St.Johns Medical College Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S510-S510, 2010.

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P7-4-6 Pseudocapsule resection may lead complete and safety removal in prolactinomas.

Yudo Ishii, Shigeyuki Tahara, Takayuki Kitamura, Akira Teramoto
Department of Neurosurgery, Nippon Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S510-S510, 2010.

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P7-4-7 Strategy for the treatment of invasive prolactinoma

Hyun Min Kim(1), Jae Won Hong(1), Moon Sool Yang Yang(2), Seung Koo Lee(4), Sun Ho Kim(2), (3), (5), Eun Jig Lee(1), (5)
(1)Department of Internal Medicine, Yonsei University College of Medicine, (2)Department of Neurosurgery, Yonsei University College of Medicine, (3)Brain Research Institute, Yonsei University College of Medicine, (4)Department of Diagnostic Radiology, Yonsei University College of Medicine, (5)Research Institute of Endocrinology, Yonsei University College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S510-S510, 2010.

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P7-4-8 Insulin sensitivity improves in patients with hyperprolactinemia after normalization of prolactin with dopamine agonists

Katarina Berinder(1), Charlotte Hoybye(1), Thomas Nystrom(2), Anna-Lena Hulting(1)
(1)Department of Molecular Medicine and Surgery, Karolinska Institutet, Dept of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, (2)Department of Internal Medicine, Karolinska Institutet, South Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S510-S510, 2010.

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P7-4-9 Macroprolactinaemia:prevalence and aetiologies

Naoki Hattori(1), Takashi Ishihara(2), Yasuhiko Saiki(2)
(1)College of Pharmaceutical Sciences, Ritsumeikan University, (2)Department of Endocrinology, Kobe City General Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S510-S511, 2010.

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P7-5-1 Solitary metastasis in the hyopthalamus associated with hypopituitarism and chiasmal syndrome

Tetsuro Tamura, Takashi Kon, Satoshi Aoki, Ryosuke Ogura
Department of Neurosurgery, Niigata Prefectural Central Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S511-S511, 2010.

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P7-5-2 Usefulness of MR imaging in multiple endocinopathies due to primary hemochoromocytosis

Tamiko Tamanaha(1), Takeshi Usui(1), (2), Ichiro Fujisawa(6), Yoshiaki Okuno(3), Sachiko Minamiguchi(4), Toshiki Komeda(5), Hitomi Iogawa(1), Hanae Hagiwara(1), Tetsuya Tagami(1), (2), Mitsuhide Naruse(1), (2), Akira Shimatsu(1), (2)
(1)Department of Endocrinology and Metabolism, National Hospital Organization Kyoto Medical Center, (2)Clinical Resarch Institute, National Hospital Organization Kyoto Medical Center, (3)Department of Hematology, National Hospital Organization Kyoto Medical Center, (4)Department of Surgical pathology, National Hospital Organization Kyoto Medical Center, (5)Department of Hepatology, National Hospital Organization Kyoto Medical Center, (6)Department of Radiology, Kishiwada City Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S511-S511, 2010.

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P7-5-3 Differential diagnosis of adrenocorticotropin(ACTH)insufficiency by a novel ultrasensitive EIA

Hideki Katakami(1), Seiich Hashida(2), Akira Matsuno(3), Nobuhiro Miyamura(4), Takeshi Usui(5), Shozo Yamada(6), Tetsuo Nishikawa(7)
(1)Div.Clin.Res.Sci., Dep.of Med., Teikyo Univ.Chiba Med.Cnt, (2)Inst.Health Sci., Tokushima Bunri Univ, (3)Dep.of Neurosurgery, Teikyo Univ.Chiba Med.Cnt, (4)Dep.Metab.Med., Kumamoto Univ, (5)Clin.Res.Inst., Kyoto Nat.Hsp, (6)Dep.Hypothalamic Pit.Surgery, Toranomon Hospital, (7)Div.Endocrinol.Metab., Yokohama Rosai Hsp
ENDOCRINE JOURNAL 57 (suppl.2-2) S511-S512, 2010.

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P7-5-4 Normal Cortisol reactivity in adults with Prader-Willi Syndrome(PWS)during insulin hypoglycemia test

Charlotte Hoybye(1), Jens S Christiansen(2)
(1)Department of Endocrinology, Metabolism and Diabetology, Karolinska University Hospital, (2)Department of Endocrinology, AArhus University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S512-S512, 2010.

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P7-5-5 A case of panhypopituitarism with a dormant period of infundibular stalk swelling

Satoru Inaba(1), Tomoko Kimura(1), Michiko Imagawa(1), Miki Fujii(1), Jinya Suzuki(1), Sadao Takahashi(1), Tadashi Konoshita(1), Isamu Miyamori(1), Ryuhei Kitai(2), Kenichiro Kikuta(2)
(1)The Third Department of Internal Medicine, University of Fukui, (2)Department of Neurosugery, University of Fukui
ENDOCRINE JOURNAL 57 (suppl.2-2) S512-S512, 2010.

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P7-5-6 Short-term risk of recurrence of surgically treated, radiotherapy(RT)-naive pituitary adenomas(PA)

Maria Fleseriu, Nicholas D.Coppa, Aclan Dogan, Christine G.Yedinak, Peter E.Andersen, Johnny B.Delashaw
Departments of Medicine and Neurological Surgery, OHSU
ENDOCRINE JOURNAL 57 (suppl.2-2) S512-S512, 2010.

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P7-5-7 Low-dose(1μg)Cortrosyn stimulation as a screening test for impaired hypothalamo-pituitary-adrenal axis(HPA):Is it time for redefinition?

Maria Fleseriu, Troy Dillard, Christine G.Yedinak, Shirley McCartney, Johnny B.Delashaw, Nicholas D.Coppa, Lynn D.Loriaux
Departments of Medicine and Neurological Surgery, Oregon Health & Science University
ENDOCRINE JOURNAL 57 (suppl.2-2) S512-S512, 2010.

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P7-5-8 Development and validation of a new QOL questionnaire for adult hypopituitarism:Adult Hypopituitarism Questionnaire(AHQ)

Hitoshi Ishii(1), Akira Shimatsu(2), (4), Kazuo Chihara(3), (4), Yasuhiko Okimura(4), Toshiaki Tanaka(4), Naomi Hizuka(4), Hidesuke Kaji(4), Kunihiko Hanew(4), Yutaka Oki(4), Sayuri Yamashiro(1)
(1)The Department of Endocrinology, Tenri Hospital, (2)Clinical Research Institute, National Hospital Organization Kyoto Medical Center, (3)Hyogo Prefectural Kakogawa Medical Center, (4)Committee on Project for AHQ Development
ENDOCRINE JOURNAL 57 (suppl.2-2) S513-S513, 2010.

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P7-5-9 Correlation of elevated thyrotropin levels with hypocortisolism in patients with Sheehans syndrome

Shariq R.Masoodi, Abdul Hamid Zargar, Arshad I.Wani, Mir Iftikhar Bashir, Bashir A.Laway, Mohammad A.Ganie, Suman Kotwal
Department of Endocrinology, Sher-i-Kashmir Institute of Medical Sciences Srinagar
ENDOCRINE JOURNAL 57 (suppl.2-2) S513-S513, 2010.

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P7-6-1 A randomized, double-blind Phase III study designed to assess the efficacy and safety of pasireotide(SOM230)in patients with Cushing's disease

Mario Maldonado(1), Rosario Pivonello(2), Feng Gu(3), Ulrike Schoenherr(3), Kapildeb Sen(4), Ke Hu(4), Annamaria Colao(2)
(1)Clinical Development, Oncology Business Unit, Novartis Pharma AG, (2)Department of Molecular and Clinical Endocrinology and Oncology, Section of Endocrinology, University of Naples ""Federico II"", (3)Peking Union Medical College Hospital, (4)Clinical Pharmacology, Oncology Business Unit, Novartis Pharmaceutical Corporation
ENDOCRINE JOURNAL 57 (suppl.2-2) S513-S513, 2010.

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P7-6-2 Diagnostic usefulness of 3.0 tesla brain MRI in Cushing's disease

Ichiro Miyata(1), Erina Ono(1), Kaori Matoba(1), Takanori Motoki(1), Hiroyuki Ida(1), Katsuyoshi Tojo(2), Junko Ito(3), Shouzou Yamada(4)
(1)Department of Pediatrics, Jikei University School of Medicine, (2)Department of Diabetes, Metabolism and Endocrinology, Jikei University School of Medicine, (3)Department of Pediatrics, Toranomon Hospital, (4)Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S513-S514, 2010.

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P7-6-3 Alcohol-induced big ACTH production in a patient with pseudo-Cushing's syndrome

Shgehiro Karashima, Toshitaka Sawamura, Masashi Ohe, Mitsuhiro Kometani, Masashi Demura, Shunsuke Mori, Takashi Yoneda, Yoshiyu Takeda
Department of Internal Medicine, Graduate School of Medical Science, Kanazawa University
ENDOCRINE JOURNAL 57 (suppl.2-2) S514-S514, 2010.

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P7-6-4 UFC response is related to pasireotide(SOM230)plasma concentrations in patients with Cushing's disease

Mario Maldonado(1), Marco Boscaro(2), Yilong Zhang(3), Kapildeb Sen(3), Ulrike Schoenherr(1), James Findling(4)
(1)Clinical Development, Oncology Business Unit, Novartis Pharma AG, (2)Division of Endocrinology, Polytechnic University of Marche, (3)Clinical Pharmacology, Oncology Business Unit, Novartis Pharmaceutical Corporation, (4)Division of Endocrinology, Metabolism, and Clinical Nutrition, Medical College of Wisconsin
ENDOCRINE JOURNAL 57 (suppl.2-2) S514-S514, 2010.

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P7-6-5 Ectopic ACTH Syndrome:A tale of two syndromes ?

Hong Chang Tan, Lih Ming Loh, Daphne Gardner, Peng Chin Kek
Department of Endocrinology, Singapore General Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S514-S514, 2010.

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P7-6-6 Differential gene expression of transcription factors in adrenocorticotropin(ACTH)-secreting pituitary and non-pituitary tumors

Yuji Tani(1), Masako Kato(1), Toru Tateno(1), Masayoshi Shichiri(1), Kenichi Oyama(2), Shozo Yamada(2), Yukio Hirata(1)
(1)Department of Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate School, (2)Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S514-S515, 2010.

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P7-6-7 Large ACTH-secreting pituitary adenoma with optic chiasma compression

Chih-Hao Kuo
Far Eastern Memorial Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S515-S515, 2010.

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P7-6-8 Bilateral inferior petrosal sinus sampling without CRH stimulation test in the differential diagnosis of Adrenocorticotropin dependent Cushing syndrome with unknown origin

Lin Lu(3), Feng Gu(1), Xiaobo Zhang(2), Zhaolin Lu(1), Zhengpei Zeng(1), Huaicheng Liu(1), Anli Tong(1), Xin Yue(1), Yong Fu(1), Zhengyu Jin(2), Zuyuan Ren(3), Renzhi Wang(3)
(1)Department of Endocrinology, Peking Union Medical College Hospital, (2)Department of Radiology, Peking Union Medical College Hospital, (3)Department of Neurosurgery, Peking Union Medical College Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S515-S515, 2010.

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P7-7-1 Circadian clock does not influence on Gonadotropin Releasing Hormone(GnRH)gene expression in GnRH-secreting GT1-7 cell line

Yusuke Tanahashi(1), (2), Tokuo Mukai(1), Kumihiro Matsuo(1), Shigeru Suzuki(1), Sato Honma(2), Kenji Fujieda(1), Ken-ich Honma(2)
(1)Department of Pediatrics, Asahikawa Medical College, (2)Department of Physiology, Hokkaido University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S515-S515, 2010.

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P7-7-2 Effect of pyrethroid insecticides on LH secretion

Nahid Parvizi(1), Dong Xia(1)
(1)Institue of Animal Genetics, (2)Shanghai Academy of Science
ENDOCRINE JOURNAL 57 (suppl.2-2) S515-S515, 2010.

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P7-7-3 Regulation of FSH transcription by GnRH and BMP in pituitary gonadotrope LβT2 cells

Masaya Takeda(1), Fumio Otsuka(1), Hiroaki Takahashi(1), Kenichi Inagaki(1), Tomoko Miyoshi(1), Naoko Tsukamoto(1), Hiroyuki Otani(1), Eri Nakamura(1), Mark A.Lawson(2), Hirofumi Makino(1)
(1)Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, (2)Department of Reproductive Medicine, University of California
ENDOCRINE JOURNAL 57 (suppl.2-2) S516-S516, 2010.

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P7-7-4 Molecular characterization of Kiss 1 gene in the pig

Junko Tomikawa(2), Tamami Homma(1), Shigeyuki Tajima(2), Takako Shibata(2), Yoko Inamoto(2), Satoshi Ohkura(1), Yoshihisa Uenoyama(1), Hiroko Tsukamura(1), Kei-ichiro Maeda(1)
(1)Graduate School of Bioagricultural Sciences, Nagoya University, (2)Aichi Agricultural Research Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S516-S516, 2010.

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P7-7-5 Gonadotropin-releasing hormone pulse generator activity from the arcuate nucleus kisspeptin neurons in the goat hypothalamus

Satoshi Ohkura(1), Yoshihiro Wakabayashi(2), Yoshihisa Uenoyama(1), Robert A.Steiner(3), Hiroko Tsukamura(1), Kei-ichiro Maeda(1), Hiroaki Okamura(2)
(1)Graduate School of Bioagricultural Sciences, Nagoya University, (2)Laboratory of Neurobiology, National Institute of Agrobiological Sciences, (3)Departments of Obstetrics & Gynecology and Physiology & Biophysics, University of Washington
ENDOCRINE JOURNAL 57 (suppl.2-2) S516-S516, 2010.

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P7-7-6 The role of FoxO1 on FSHβ gene regulation in the pituitary

Young Suk Choi(1), Eun Jig Lee(2)
(1)Brain Korea 21 project for Medical Science, Yonsei University College of Medicine, (2)Department of Endocrinology, Yonsei University, college of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S516-S516, 2010.

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P7-7-7 Induction of ovulation by kisspeptin and its agonists in the musk shrew(Suncus murinus), a reflex ovulator.

Naoko Inoue(1), Yuki Sasaki(1), Shinya Oishi(2), Nobutaka Fujii(2), Yoshihisa Uenoyama(1), Naoyuki Yamamoto(1), Hiroko Tsukamura(1), Kei-ichiro Maeda(1)
(1)Graduate School of Bioagricultural Sciences Nagoya University, (2)Graduate School of Pharmaceutical Sciences, Kyoto University
ENDOCRINE JOURNAL 57 (suppl.2-2) S517-S517, 2010.

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P7-7-8 Gonadal hormone-independent regulation of hypothalamic Kiss1/NKB neurons in prepubertal mice

Alexander S.Kauffman(1), Victor M.Navarro(2), Josh Kim(2), Donald K.Clifton(2), Robert A.Steiner(2)
(1)Department of Reproductive Medicine, University of California San Diego, (2)Department of Physiology and Biophysics, University of Washington
ENDOCRINE JOURNAL 57 (suppl.2-2) S517-S517, 2010.

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P7-8-1 Repeated glucoprivation delayed hyperphagic responses in rats

Yoshiharu Ozawa, Hiroshi Arima, Minemori Watanabe, Hiroshi Shimizu, Masayuki Hayashi, Yutaka Oiso
Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S517-S517, 2010.

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P7-8-2 Roles of ghrelin in the control of growth hormone secretion

Hiroyuki Ariyasu(1), Hiroshi Iwakura(1), Go Yamada(2), Naotetsu Kanamoto(2), Kenji Kohno(3), Takahiro Sato(4), Masayasu Kojima(4), Kazuwa Nakao(2), Kenji Kangawa(5), Takashi Akamizu(1)
(1)Translational Research Center, Kyoto University Hospital, (2)Department of Endocrinology and Metabolism, Kyoto University Graduate School of Medicine, (3)Laboratory of Molecular and Cell Genetics, Graduate School of Biological Sciences, Nara Institute of Science and Technology, (4)Morecular genetics, Institute of Life Sciences, Kurume University, (5)Department of Biochemistry, National Cardiovascular Center Research Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S517-S518, 2010.

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P7-8-3 Insulin-like growth factor-I inhibits Ghrelin receptor gene expression in cultured rat pituitary cells

Rena Makino, Nobuhiro Miki, Masami Ono, Toshiro Seki, Kazue Takano
Department of Medicine II, Institute of Clinical Endocrinology, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S518-S518, 2010.

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P7-8-4 Peripheral secretin reduced food intake in fasted mice

Carrie Y.Y.Cheng, Billy K.C.Chow
School of Biological Sciences, The University of Hong Kong
ENDOCRINE JOURNAL 57 (suppl.2-2) S518-S518, 2010.

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P7-8-5 The anorexigenic neuropeptide, nesfatin-1:A putative neuroendocrine integrator linking energy balance and puberty onset?

Victor M.Navarro(1), David Garcia-Galiano(1), Juan Roa(1), Miguel A.Sanchez-Garrido(1), F Ruiz-Pino(1), Rafael Pineda(1), Juan M.Castellano(1), M.Romero(1), Enrique Aguilar(1), Carlos Dieguez(2), Leonor Pinilla(1), Manuel Tena-Sempere(1)
(1)Department of Cell Biology, Physiology and Immunology & CIBERobn Fisiopatologia de la Obesidad y Nutricion.University of Cordoba, (2)Department of Physiology & CIBERobn.University of Santiago de Compostela
ENDOCRINE JOURNAL 57 (suppl.2-2) S518-S518, 2010.

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P7-8-6 Parabrachial nucleus is a new target of orexigenic action of ghrelin

Karolina P.Skibicka, Emil Egecioglu, Suzanne L Dickson
Department of Physiology/Endocrinology, The Sahlgrenska Academy at The University of Gothenburg
ENDOCRINE JOURNAL 57 (suppl.2-2) S518-S518, 2010.

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P7-8-7 Insulin-like growth factor(IGF)-I represses 11β-HSD1 activity via regulation of hexose-6-phosphate dehydrogenase(H6PDH)mRNA in 3T3-L1 adipocytes

Yukiko Ishikawa(1), Junko Morita(1), Naomi Hizuka(1), Izumi Fukuda(1), Fumihiko Hakuno(2), Shin-Ichiro Takahashi(2), Kazue Takano(1)
(1)Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, (2)Department of Animal Science, Graduate School of Agriculture and Life Sciences, The University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S519-S519, 2010.

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P7-8-8 Molecular cloning and tissue distribution of Foxo1 in Nile tilapia(Oreochromis niloticus)and effects of food-intake and insulin on Foxo1 mRNA expression

Wensheng Li, Yalu Zhou, Xin Wang, Wenbo Chen
State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University
ENDOCRINE JOURNAL 57 (suppl.2-2) S519-S519, 2010.

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P7-9-1 Clinical characteristics of Japanese adult patients with severe GH deficiency:Data from post-marketing surveillance of Humatrope

Shigeru Tai(1), Akira Shimatsu(2), Toshiaki Tanaka(3), Kenji Fujieda(4), Akira Teramoto(5), Kazuo Chihara(6)
(1)Eli Lilly Japan K.K, (2)Clinical Research Institute, National Hospital Organization Kyoto Medical Center, (3)Tanaka Growth Clinic, (4)Department of Pediatric, Asahikawa Medical College, (5)Department of Neurosurgery, Nippon Medical School, (6)Hyogo Prefectural Kakogawa Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S519-S519, 2010.

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P7-9-2 Clinical characteristics of adult growth hormone deficiency associated with non-alcoholic fatty liver disease

Makiko Kurimoto, Izumi Fukuda, Naomi Hizuka, Satoshi Tanaka, Yu Yamakado, Kumiko Yasumoto, Kazue Takano
Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S519-S520, 2010.

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P7-9-3 GH and IGF-I ameliorate inflammation and fibrosis in a mouse model of non alcoholic steatohepatitis

Hitoshi Nishizawa(1), Genzo Iguchi(1), Michiko Takahashi(1), Masaaki Yamamoto(1), Anastasia-Evi Handayaningsih(1), Riko Kitazawa(2), Yasuhiko Okimura(3), Hidesuke Kaji(4), Sohei Kitazawa(2), Yoshitake Hayashi(5), Kazuo Chihara(6), Susumu Seino(1), (7), Yutaka Takahashi(1)
(1)Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, (2)Division of Molecular Pathology, Department of Biomedical Informatics, Kobe University School of Medicine, (3)Department of Basic Allied Medicine, Kobe University School of Medicine, (4)Division of Physiology/Metabolism, University of Hyogo, (5)Division of Molecular Medicine and Medical Genetics, International Center of Medical Research and Treatment, Kobe University School of Medicine, (6)Hyogo Prefectural Kakogawa Hospital, (7)Division of Cellular and Molecular Medicine, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S520-S520, 2010.

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P7-9-4 The Estimated Glomerular Filtration Rate(eGFR)in Patients with Adult Growth Hormone Deficiency(AGHD)

Yu Yamakado, Naomi Hizuka, Makiko Kurimoto, Satoshi Tanaka, Izumi Fukuda, Kazue Takano
Department of Medicine, Insutitute of Clinical Endocrinology, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S520-S520, 2010.

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P7-9-5 Population PK/PD model for pegylated, long-acting human growth hormone in caucasian and Japanese healthy subjects

Thomas Klitgaard, Jesper Madsen, Lene Jensen, Britta Bysted, Michael Hojby Rasmussen
Novo Nordisk A/S
ENDOCRINE JOURNAL 57 (suppl.2-2) S520-S520, 2010.

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P7-9-6 Recently approved indications for human growth hormone pharmaceuticals in Japan:Review of applications for use in small for gestational age and adult gh deficiency patients at PMDA

Mai Hirano, Toshio Makie, Yukie Sano, Fumiko Matsuda, Mari Ishida, Kayo Shinohara, Junichi Asano, Michihiro Ogawa, Naoto Kato, Rumiko Hosoki, Masanobu Yamada, Masakazu Hirata
Pharmaceuticals and Medical Devices Agency
ENDOCRINE JOURNAL 57 (suppl.2-2) S520-S521, 2010.

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P7-9-7 GH insufficiency and GH insensitivity coexist in severe fibromyalgia syndrome

Guillem Cuatrecasas(1), Manuel Puig-Domingo(2), Maria Jose Gonzalez(3), Gemma Sesmilo(4), Fernandez-Sola Joaquim(5), Cayetano Alegre(3)
(1)Endocrinology Department, CM Teknon, (2)Endocrinology Department, Hospital Clinic, Universitat Barcelona, (3)Rheumatology Department, Institut Universitari Dexeus, (4)Endocrinology Department, Institut Universitari Dexeus, (5)Internal Medicine, Hospital Clinic, Universitat Barcelona
ENDOCRINE JOURNAL 57 (suppl.2-2) S521-S521, 2010.

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P7-9-8 Quality of life(QoL)in adults with growth hormone deficiency(GHD):Validation of QoL-aghda into Brazilian Portuguese

Maria Koltowska-Haggstrom(1), Anders Mattson(2), A.Jr.Ribeiro-Oliveira(3), S.S.Mol(3), J.Twiss(4), G.A.Alencar(3), L.A.Naves(5), C.L.Boguszewski(6), K.Camarano(7), L.Vilar(8), S.P.McKenna(4)
(1)Pfizer Endocrine Care International, (2)KIMS Medical Outcomes, (3)Federal University of Minas Gerais, (4)Galen Research Ltd, (5)Universidade Federal de Brasilia(UnB), (6)SEMPR, Universidade Federal do Parana, (7)Hospital do Brigadeiro, (8)Universidade Federal de Pernambuco
ENDOCRINE JOURNAL 57 (suppl.2-2) S521-S521, 2010.

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P7-10-1 Expression of mTOR signaling pathway and the effects of mTOR inhibitor on cell signaling pathway in neuroendocrine tumors

Shinya Iida, Yasuhiro Miki, Katsuhiko Ono, Hironobu Sasano
Department of Pathology, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S521-S521, 2010.

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P7-10-2 Silent thyrotroph pituitary adenoma coexisting with autoimmune thyroiditis

Kuo-Yang Lee, Tien-Shang Huang
Endocrine and metabolism department, National Taiwan University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S521-S522, 2010.

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P7-10-3 TSH-oma rare cause of hyperthyroidism-a case report

Aldona Kowalska(1), Pawel Samborski(2), Wieslaw Bonicki(3), Iwona Palyga(1), Danuta Gasior-Perczak(1)
(1)Department of Endocrinology and Nuclear Medicine, Holycross Cancer Centre, (2)Department of Internal Medicine, City Hospital, (3)Department of CNS Neoplasms, Oncology Centre
ENDOCRINE JOURNAL 57 (suppl.2-2) S522-S522, 2010.

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P7-10-4 TSH secreting pituitary adenoma presenting as hyperthyroidism

Santosh K.Chaubey(1), Jennifer Yarker(2), (3), Ashim K.Sinha(2)
(1)Department of Endocrinology and Diabetes, The Townsville Hospital, (2)Department of Endocrinology and Diabetes, Cairns Base Hospital, (3)Department of Medicine, James Cook University
ENDOCRINE JOURNAL 57 (suppl.2-2) S522-S522, 2010.

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P7-10-5 Prolonged biotherapy with somatostatin analogue in patients with thyrotropinoma-effectiveness over 5 years

Piotr Zdunowski, Wojciech Zgliczynski
Department of Endocrinology, Medical Center of Postgraduate Education
ENDOCRINE JOURNAL 57 (suppl.2-2) S522-S522, 2010.

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P7-10-6 Octreotide and lanreotide responder groups are not strictly overlapping

Piotr Zdunowski, Wojciech Zgliczynski
Department of Endocrinology, Medical Center of Postgraduate Education
ENDOCRINE JOURNAL 57 (suppl.2-2) S522-S522, 2010.

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P7-10-7 Neurohypophyseal germinoma:characteristics and treatment outcome in 14 cases

Kenichi Oyama(1), Shozo Yamada(1), Noriaki Hukuhara(1), Nobuaki Ito(2), Akira Takeshita(2), Yasuhiro Takeuchi(2), Junko Ito(3)
(1)Endocrine Center, Department of Hypothalamic & Pituitary Surgery, Toranomon Hospital, (2)Endocrine Center, Department of Endocrinology, Toranomon Hospital, (3)Endocrine Center, Department of Pediatrics, Toranomon Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S523-S523, 2010.

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P7-10-8 Pituicytoma case report:A rare tumor with a rare presentation

Andre Carvalho(1), Gustavo Rocha(1), Alfonso Velasco(2), Rodrigo Pedrosa(2), Isabel Ribeiro(2), Fatima O.Borges(1)
(1)Department of Endocrinology, Sto.Antonio Hospital, (2)Department of Neurosurgery
ENDOCRINE JOURNAL 57 (suppl.2-2) S523-S523, 2010.

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P7-11-1 Expression of somatostatin receptor subtypes in nonfunctioning pituitary adenomas:Correlation with expression of estrogen receptor-α

Hiroshi Nishioka(1), (3), Kazuhiro Tamura(2), Haruka Iida(2), Masahiko Kutsukake(2), Aiju Endo(2), Yukio Ikeda(3), Jo Haraoka(1)
(1)Department of Neurosurgery, Tokyo Medical University, (2)Department of Endocrine Pharamacology, Tokyo University of Pharamacy & Life Sciences, (3)Department of Neurosurgery, Hachioji Medical Center, Tokyo Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S523-S523, 2010.

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P7-11-2 CD133-a potential stem cell marker in human pituitary adenomas

Maya Tobita(1), (2), Takashi Miyakoshi(2), Susumu Takekoshi(2), Robert Y Osamura(2), Katsuyoshi Tojo(1), Naoko Tajima(1), Shozo Yamada(3)
(1)Division of diabetes, Metabolism and Endocrinology, Department of Internal Medicine, the Jikei University School of Medicine, (2)Department of Pathology, Tokai University School of Medicine, (3)Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S523-S523, 2010.

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P7-11-3 Quantitative analysis of dopamine D2 receptor expression in clinically non-functioning adenomas

Filip Gabalec(1), Jan Cap(1), Martin Beranek(2), David Netuka(4), Vaclav Masopust(4), Jiri Nahlovsky(3)
(1)The Second Department of Internal Medicine, Charles University Faculty of Medicine and Teaching Hospital in Hradec Kralove, (2)Institute for Clinical Biochemistry and Diagnostics, Charles University Faculty of Medicine and Teaching Hospital in Hradec Kralove, (3)Department of Neurosurgery, Charles University Faculty of Medicine and Teaching Hospital in Hradec Kralove, (4)Department of Neurosurgery, First Faculty of Medicine, Charles University in Prague and Central Military Hospital Prague
ENDOCRINE JOURNAL 57 (suppl.2-2) S524-S524, 2010.

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P7-11-4 The endoscopic surgery improves the outcome of the transsphenoidal surgery in the patients with functional pituitary adenomas

Atsushi Tominaga(1), Kazunori Arita(2), Yasuyuki Kinoshita(1), Tetsuhiko Sakoguchi(3), Satoshi Usui(1), Kuniki Eguchi(1), Kaoru Kurisu(1)
(1)Department of Neurosurgery, University of Hiroshima, (2)Department of Neurosurgery, University of Kagoshima, (3)Department of Neurosurgery, Onomichi General Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S524-S524, 2010.

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P7-11-5 Extracapsular removal of the pituitary adenomas has accomplished 100% cure rate in GH adenomas of Knosp grade 0-1

Tomokatsu Hori
The Department of Neurosurgery, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S524-S524, 2010.

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P7-11-6 Clinically non-functioning pituitary adenoma in younger patients

Noriaki Fukuhara(1), Kenichi Oyama(1), Naoko Inoshita(2), Akira Takeshita(3), Yasuhiro Takeuchi(3), Toshiaki Sano(4), Shozo Yamada(1)
(1)The Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital, (2)The Department of Pathology, Toranomon Hospital, (3)The Department of Endocrinology and Metabolism, Toranomon Hospital, (4)The Department of Human Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School
ENDOCRINE JOURNAL 57 (suppl.2-2) S524-S524, 2010.

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P7-11-7 Endocrinological evaluation for clinically non-functioning pituitary adenoma:analysis of 223 surgically treated cases

Kosaku Amano(1), Takakazu Kawamata(2), Masami Ono(3), Toshiro Seki(3), Izumi Fukuda(3), Akiyo Tanabe(3), Tsutomu Isozaki(3), Nobuhiro Miki(3), Naomi Hiduka(3), Kazue Takano(3), Osami Kubo(1), Yoshikazu Okada(1), Tomokatsu Hori(4)
(1)Department of Neurosurgery, Tokyo Women's Medical University, (2)Department of Neurosurgery, Tokyo Women's Medical University Yachiyo Medical Center, (3)Department of Medicine II, Tokyo Women's Medical University, (4)Department of Neurosurgery, Moriyama memorial hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S525-S525, 2010.

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P7-11-8 The value of routine ultrasound scanning in long term octreotide analogue lanreotide(Somatuline Autogel)therapy

Thomas Ulahannan, Donna Norman, David Farrugia
Departments of Endocrinology & Oncology, Gloucestershire Royal Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S525-S525, 2010.

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P7-12-1 Tremor in Klinefelter syndrome improved by testosterone administration

Hiroyuki Kinoshita(1), Takuya Ohkubo(1), (2), Nozomu Satoh(2), Saneyuki Mizutani(1), (2), Mutsuko Yasuda(1), Akira Machida(1), (2), Kinya Ishikawa(2), Tomoyuki Kamata(1), (2), Fumiatsu Yakushiji(1)
(1)Department of Internal Medicine, Tokyo Metropolitan Bokutoh Hospital, (2)Department of Neurology and Neurological Science, Tokyo Medical and Dental University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S525-S525, 2010.

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P7-12-2 Hypothalamic-pituitary-gonadal function and predictors for recovery of menstruation in anorexia nervosa

Ayako Urano(1), Rina Ohwada(1), Mari Hotta(1), (2), Mariko Araki(1), Kazue Takano(1)
(1)Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, (2)Health Services Center, National Graduate Institute for Policy Studies
ENDOCRINE JOURNAL 57 (suppl.2-2) S525-S525, 2010.

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P7-12-3 Three cases of ovarian hyperstimulation caused by gonadotroph adenoma in Japanese women

Emi Imada, Tomoaki Tanaka, Keiko Suyama, Tomohiko Yoshida, Kotaro Yokote, Ichiro Tatsuno
Department of Clinical Cell Biology, Chiba University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S526-S526, 2010.

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P7-12-4 Amenorrhea resulting from polycystic ovary syndrome(PCOS)secondary to growth hormone(GH)producing pituitary adenoma

Satoko Watanabe, Sanae Midorikawa, Yoshiyuki Sugaya, Miyuki Honma, Machii Noritaka, Hiroyuki Hirai, Akihiro Kudo, Koji Hasegawa, Makoto Fugiwara, Shiniti Nakagima, Hiroaki Satoh, Tsuyoshi Watanabe
Department of Diabetology, Endocrinology and Metabolism, Fukushima Medical University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S526-S526, 2010.

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P7-12-5 Beneficial effect of intravaginal DHEA in postmenopausal women suffering from vaginal atrophy and having identified pain at intercourse(dyspareunia)as their most bothersome symptom

Fernand Labrie(1), (2), David Archer(3), Celine Bouchard(4), Michel Fortier(4), Leonello Cusan(1), Ginette Girard(5), Mira Baron(6), Normand Ayotte(7), Michele Moreau(8), Robert Dube(9), Isabelle Cote(2), Claude Labrie(1), (2), Lyne Lavoie(2), Celine Martel(2), John Balser(10)
(1)Laval University Hospital Research Center(CRCHUL) and Laval University, (2)Endoceutics Inc, (3)Clinical Research Center, Eastern Virginia Medical School, (4)Clinique de recherche en sante des femmes, (5)Diex Recherche Inc, (6)Rapid Medical Research Inc, (7)Clinique Gynecologique, (8)Montreal Clinical Study Center, (9)Centre hospitalier affilie universitaire de Quebec, (10)Veristat Inc
ENDOCRINE JOURNAL 57 (suppl.2-2) S526-S526, 2010.

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P7-12-6 Highly variable and low to very low serum DHEA levels in postmenopausal women

Fernand Labrie(1), (2), Celine Martel(2)
(1)Laval University Hospital Research Center(CRCHUL) and Laval University, (2)Endoceutics Inc
ENDOCRINE JOURNAL 57 (suppl.2-2) S526-S526, 2010.

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P7-12-7 High efficacy of intravaginal DHEA on all symptoms and signs of vaginal atrophy

Fernand Labrie(1), (2), David Archer(3), Celine Bouchard(4), Michel Fortier(4), Leonello Cusan(1), Ginette Girard(5), Mira Baron(6), Normand Ayotte(7), Michele Moreau(8), Robert Dube(9), Isabelle Cote(2), Claude Labrie(1), (2), Lyne Lavoie(2), Celine Martel(2), John Balser(10)
(1)Laval University Hospital Research Center(CRCHUL) and Laval University, (2)Endoceutics Inc, (3)Clinical Research Center, Eastern Virginia Medical School, (4)Clinique de recherche en sante des femmes, (5)Diex Recherche Inc, (6)Rapid Medical, Research Inc, (7)Clinique Gynecologique, (8)Montreal Clinical Study Center, (9)Centre hospitalier affilie universitaire de Quebec, (10)Veristat Inc
ENDOCRINE JOURNAL 57 (suppl.2-2) S527-S527, 2010.

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P7-12-8 Behavioral profile in ovariectomized female Hatano high-and low-avoidance rats

Maiko Kawaguchi(1), Ryo Ohta(2), Hiroko Makihara(1), Gen Watanabe(3), (4), Kazuyoshi Taya(3), (4), Tsutomu Shimada(1), Masaki Aburata(1), Nobumasa Kato(5), Toshiyuki Himi(1)
(1)Research Institute of Pharmaceutical Science, Musashino University, (2)Hatao Research Institute, Food and Drug Safety Center, (3)Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, (4)Department of Basic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, (5)Department of Psychiatry, School of Medicine, Showa University
ENDOCRINE JOURNAL 57 (suppl.2-2) S527-S527, 2010.

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P7-13-1 Effects of somatostatin analogues on ACTH production through BMP-4 actions in AtT20 corticotrope cells

Naoko Tsukamoto(1), Fumio Otsuka(1), Tomoko Miyoshi(1), Masaya Takeda(1), Hiroyuki Otani(1), Jiro Suzuki(1), Kenichi Inagaki(1), Eri Nakamura(1), Yukari Mimura(1), Toshio Ogura(1), Yasumasa Iwasaki(2), Hirofumi Makino(1)
(1)Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, (2)Department of Endocrinology, Metabolism, and Nephrology, Kochi Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S527-S527, 2010.

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P7-13-2 Nuclear translocation of glucocorticoid receptor(GR)in the brain and pituitary during acute and repeated Immobilization(IMO)stress

Shinya Makino(1), (2), Tohru Noguchi(1), (3), Reiko Matsumoto(1), Mitsuru Nishiyama(1), Yoshio Terada(1), Kozo Hashimoto(1)
(1)Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, (2)Department of Internal Medicine, Osaka Gyomeikan Hospital, (3)Department of Lipidology, Graduate School of Medical Science, Kanazawa University
ENDOCRINE JOURNAL 57 (suppl.2-2) S527-S528, 2010.

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P7-13-3 Local peripheral transformation as main source of steroid hormones in the human brain

Vanni Frajese(1), Vincent Agrapart(1), Dorina Ylli(1), Dick Swaab(2)
(1)Department of Internal Medicine, Chair of Endocrinology, University of Rome Tor Vergata, (2)Netherlands Institute for Neroscience
ENDOCRINE JOURNAL 57 (suppl.2-2) S528-S528, 2010.

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P7-13-4 Non genomic action of mineralocorticoid receptor in the CNS and ROS

Fumiko Mori, Tatsuo Shimosawa, Shengyu Mu, Yuzaburo Uetake, Hoang Wang, Toshiro Fujita
Nephrology and Endocrinology The University of Tokyo Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S528-S528, 2010.

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P7-13-5 The suppressive effect of glucocorticoid on ACTH response to GHRP2

Satoru Sakihara, Kazunori Kageyama, Shinobu Takayasu, Takako Moriyama, Ken Terui, Takeshi Nigawara, Toshihiro Suda
Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S528-S528, 2010.

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P7-13-6 The role of mineralocorticoid receptor expression in brain remodeling after cerebral ischemia

Naofumi Oyamada(1), Masakatsu Sone(1), Kazutoshi Miyashita(1), Kwijun Park(1), Daisuke Taura(1), Megumi Inuzuka(1), Takuhiro Sonoyama(1), Yasutomo Fukunaga(1), Naohisa Tamura(1), Hiroshi Itoh(2), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Internal Medicine, Keio University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S528-S528, 2010.

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P7-13-7 Signalling pathway mediated by CXCR7 in AtT20 pituitary adenoma cells

Kenta Koketsu, Daizo Yosida, Akira Teramoto
Department of Neurosurgery, Nippon Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S528-S529, 2010.

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P7-13-8 Effect of estradiol on the expression of the TNF-α/TNFR1 system in anterior pituitary cells

Adriana Seilicovich, Veronica Zaldivar, Maria Laura Magri, Sandra Zarate, Gabriela Jaita, Guadalupe Eijo, Daniel Pisera
Instituto de Investigaciones en Reproduction, Facultad de Medicina, Universidad de Buenos Aires
ENDOCRINE JOURNAL 57 (suppl.2-2) S529-S529, 2010.

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P7-14-1 In vivo characteristics of salsolinol on the secretion of prolactin in ruminants

Tsutomu Hashizume(1), Tatsuru Sawada(1), Tomoyoshi Yaegashi(1), Hayato Saito(1), Yuka Nakajima(1), Yuki Goto(1), Ahmed Ezzat Ahmed(1), Jin Jin(1), Ken Sawai(1), Etsuko Kasuya(2), Gyorgy M.Nagy(3)
(1)Faculty of Agriculture, Iwate University, (2)Neurobiology Research Unit, National Institute of Agrobiological Sciences, (3)Neuromorphological and Neuroendocrine Research Laboratory, Department of Human Morphology, Hungarian Academy of Science and Semmelweis University
ENDOCRINE JOURNAL 57 (suppl.2-2) S529-S529, 2010.

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P7-14-2 Down-regulated expression of p18INK4C in pituitary adenomas

Katsuhiko Yoshimoto(1), Md.Golam Hossain(1), Takeo Iwata(1), Noriko Mizusawa(1), Shahidan Wan Nazatul Shima(1), Toru Okutsu(1), Kyoko Ishimoto(1), Zhi Rong Qian(2), Toshiaki Sano(2), Shozo Yamada(3)
(1)Department of Medical Pharmacology, Institute of Health Biosciences, The University of Tokushima Graduate School, (2)Department of Human Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School, (3)Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S529-S529, 2010.

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P7-14-3 Identification and characterization of a heterozygous microdeletion affecting LHX4 in a patient with combined pituitary hormone deficiency

Sumito Dateki(1), (2), Ayumi Uematsu(3), Masayuki Kaji(3), Katsuaki Motomura(2), Eiichi Kinoshita(4), Hiroyuki Moriuchi(2), Maki Fukami(1), Tsutomu Ogata(1)
(1)Department of Endocrinology and Metabolism, National Research Institute for Child Health and Development, (2)Department of Pediatric, Nagasaki University Graduate School of Biomedical Sciences, (3)Division of Endocrinology and Metabolism, Shizuoka Children's Hospital, (4)Kinoshita Children's Clinic
ENDOCRINE JOURNAL 57 (suppl.2-2) S529-S530, 2010.

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P7-14-4 gsp mutations and the MLL-p27Kip1 pathway in pituitary adenoma

Kazuhiko Horiguchi(1), Masanobu Yamada(1), Ryo Taguchi(1), Atsushi Ozawa(1), Nobuyuki Shibusaswa(1), Koshi Hashimoto(1), Tetsurou Satoh(1), Masahiko Tosaka(2), Shozo Yamada(3), Masatomo Mori(1)
(1)Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, (2)Department of Neurosurgery, Gunma University Graduate School of Medicine, (3)Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S530-S530, 2010.

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P7-14-5 GH receptor His49Arg mutation was not detected in Japanese acromegalics

Koji Takano(1), Junko Yasufuku-Takano(1), Shigetoshi Mori(1), Shozo Yamada(2), Akira Teramoto(3), Toshiaki Sano(4), Toshiro Fujita(1)
(1)Department of Nephrology and Endocrinology, University of Tokyo Faculty of Medicine, (2)Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital, (3)Department of Neurosurgery, Nippon Medical School, (4)Department of Pathology, Institute of Health Biosciences, The University of Tokushima Graduate School
ENDOCRINE JOURNAL 57 (suppl.2-2) S530-S530, 2010.

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P7-14-6 SAGE analysis highlights the importance of ribosomal protein under-expression in gh secreting pituitary tumorigenesis

Sonir R.Antonini(1), Deison S.Lima(2), Beatriz M.C Paixao(2), Fernando C.Amaral(2), Daniel G.Pinheiro(2), Fabiano P.Saggioro(2), Anemari R.D.Santos(2), Helio R.Machado(2), Ayrton C.Moreira(2), Wilson A.Silva Jr.(2), Margaret Castro(2)
(1)Department of Pediatrics, School of Medicine of Ribeirao Preto, University of Sao Paulo, (2)Department of Internal Medicine-School of Medicine of Ribeirao Preto, University of Sao Paulo
ENDOCRINE JOURNAL 57 (suppl.2-2) S530-S530, 2010.

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P7-14-7 Impact of Gsp gene mutation on cytokeratin expressions and clinocopathological features of GH producing adenoma

Yuriz Bakhtiar(1), Kazunori Arita(1), Hirofumi Hirano(1), Shunji Yunoue(1), Shingo Fujio(1), Atsushi Tominaga(1), Tetsuhiko Sakoguchi(2), Kazuhiko Sugiyama(2), Kaoru Kurisu(2), Koji Takano(3), Junko F Takano(3)
(1)Neurosurgery Department, Kagoshima University, (2)Department of Neurosurgery, Hiroshima University, (3)Department of Nephrology and Endocrinology, the University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S530-S531, 2010.

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P7-14-8 ER stress triggered by unfolded and mutant GH is involved in isolated growth hormone deficiency type 2

Daisuke Ariyasu(1), Makoto Yamada(1), Toshimi Michigami(2), Hiderou Yoshida(3), Masako Izawa(1), Junko Miyamoto(1), Yukihiro Hasegawa(1)
(1)The Endrocrinology Unit of Tokyo Metropolitan Kiyose Children's Hospital, (2)Department of Bone and Mineral Research, Osaka Medical Center and Research Institute for Maternal and Child Health, (3)Department of Biophysics, Graduate School of Science, Kyoto University
ENDOCRINE JOURNAL 57 (suppl.2-2) S531-S531, 2010.

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P7-15-1 Wide distribution of serum sodium depends upon inappropriate and appropriate secretion of arginine vasopressin(AVP)in acute infectious diseases

Masami Sasaki(1), Masanobu Kawakami(2), San-e Ishikawa(2)
(1)Hannou Municipal Naguri Clinic, (2)Department of Medicine, Jichi Medical University Saitama Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S531-S531, 2010.

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P7-15-2 Comparison of the neurological sequelae after rapid correction of hyponatremia between by vasopressin receptor antagonist mozavaptan(OPC-31260)and by hypertonic saline in rats

Haruyuki Suzuki(1), Yoshihisa Sugimura(1), Shintaro Iwama(1), Hiroshi Nagasaki(2), Hiroshi Arima(1), Yutaka Oiso(1)
(1)Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, (2)Department of Metabolic Medicine, Nagoya University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S531-S531, 2010.

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P7-15-3 Hyponatremia is a useful tool for diagnosis of hypopituitarism in elderly

Tomoko Asano, Yoshida Masashi, Kimoto Mizuho, Murata Miho, Saito Tomoyuki, Ikoma Aki, Kawakami Masanobu, San-e Ishikawa
Department of medicine, Jichi Medical University Saitama Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S531-S532, 2010.

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P7-15-4 Forebrain mechanisms activated by amino acid receptors to control vasopressin release in response to a hyperosmotic or a hypovolemic stimulus

Ken'ichi Yamaguchi(1), Takaho Yamada(1), Hitoshi Hama(2), Kanemitsu Yamaya(3)
(1)Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, (2)Kido Hospital, (3)Oyokyo Kidney Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S532-S532, 2010.

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P7-15-5 The cause of disease and antidiuretic hormone(ADH)level in patients with syndrome of inappropriate antidiuretic hormone secretion(SIADH)in Korea

Mi Young Lee, Jae Hyun Kim, Song Yi Kim, Jang Yel Shin, Young Goo Shin, Choon Hee Chung
Department of Internal Medicine, Yonsei University Wonju College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S532-S532, 2010.

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P7-15-6 Syndrome of inappropriate antidiuretic hormone secretion associated with acute porphyria

Taku Oba(1), Ikuo Yamamori(2), Takashi Murase(2), Yoshiko Mori(1), Takeo Yamaguchi(1)
(1)Department of General Medicine, Japanese Red Cross Nagoya Daiichi Hospital, (2)Department of Endocrinology and Metabolism, Japanese Red Cross Nagoya Daiichi Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S532-S532, 2010.

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P7-15-7 Acute severe hyponatremia due to hypothalamus-pituitary failure after traumatic brain injury

Jiang Ju Ying
Division of Endocrinology and Metabolism, Department of Internal Medicine, Far Eastern Memorial Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S532-S533, 2010.

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P7-15-8 Two cases of severe hyponatremia in voltage-gated potassium channel antibody-associated limbic encephalitis

Naoko Hashimoto, Tomoaki Tanaka, Kotaro Yokote, Ichiro Tatsuno
Department of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Division of Endocrinology and Metabolism, Chiba University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S533-S533, 2010.

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P7-16-1 Follistatin, induced by thyrotropin-releasing hormone(TRH), plays no role in prolactin expression but affects gonadotropin FSHβ expression as a paracrine factor in pituitary somatolactotroph GH3 cells

Haruhiko Kanasaki, Aki Oride, Indri N Purwana, Kohji Miyazaki
Shimane University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S533-S533, 2010.

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P7-16-2 Relationship between neurotrophin 3 and neuropeptide Y in myelination of the mouse cerebrum during the lactation period

Ryuju Hashimoto, Akihiro Matsumoto, Takayuki Inoue, Jun Udagawa, Hiroki Otani
Department of Developmental Biology, Faculty of Medicine, Shimane University
ENDOCRINE JOURNAL 57 (suppl.2-2) S533-S533, 2010.

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P7-16-3 Effect of neonatal estrogen on brain kisspeptin expression in adult mice:possible role of estrogen receptor α

Kae Yoshida, Tamami Homma, Yoko Inamoto, Junko Tomikawa, Yoshihisa Uenoyama, Kei-ichiro Maeda, Hiroko Tsukamura
Graduate School of Bioagricultural Sciences, Nagoya University
ENDOCRINE JOURNAL 57 (suppl.2-2) S533-S534, 2010.

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P7-16-4 Acute trapping of peripubertal kisspeptin or leptin with antibodies to determine factors triggering the onset of puberty in female rats

Yoshihisa Uenoyama, Kenji Takase, Junya Hirata, Akira Tanaka, Hiroko Tsukamura, Kei-ichiro Maeda
Graduate School of Bioagricultural Sciences, Nagoya University
ENDOCRINE JOURNAL 57 (suppl.2-2) S534-S534, 2010.

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P7-16-5 Defect of CIN85 suppresses mother's parenting behavior through dopamine-prolactin system

Jun Ikezawa(1), Noriaki Shimokawa(1), Kaisa Haglund(2), Ivan Dikic(3), Noriyuki Koibuchi(1)
(1)Department of Integrative Physiology, Gunma University Graduate School of Medicine, (2)Department of Biochemistry, Cancer Research at the Norwegian Radium Hospital, (3)Institute of Biochemistry II, Goethe University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S534-S534, 2010.

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P7-16-6 Hypothalamic expression of the kisspeptin gene(Kiss1)and the RFamide-related peptide(RFRP)gene during the menstrual cycle of a non-human primate

Jeremy T.Smith(1), Alda Periera(1), Muhammad Shahab(2), K.-Y.Francis Pau(3), Iain J.Clarke(1)
(1)Department of Physiology, Monash University, (2)Qauid-i-Azam University, (3)Oregon Health and Science University
ENDOCRINE JOURNAL 57 (suppl.2-2) S534-S534, 2010.

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P7-16-7 The significance of the depletion of neonatal testicular androgens to rescue anteroventral periventricular Kiss1 neurons and GnRH/LH surge in male rats

Tamami Homma(1), (2), Shunji Yamada(2), Kinuyo Iwata(2), Junko Tomikawa(2), Yoshihisa Uenoyama(2), Kei-ichiro Maeda(2), Hiroaki Okamura(1), Hiroko Tsukamura(2)
(1)Laboratory of Neurobiology, National Institute of Agrobiological Sciences, (2)Laboratory of Reproductive Science, Graduate School of Bioagricultural Sciences, Nagoya University
ENDOCRINE JOURNAL 57 (suppl.2-2) S534-S534, 2010.

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P7-16-8 Analysis of pituitary-rich KIAA1324/maba1 in prolactin secretion

Kazuyoshi Kousaka, Ke-ita Tatsumi, Yoh Hidaka
Departent of Laboratory Medicine, Osaka University
ENDOCRINE JOURNAL 57 (suppl.2-2) S535-S535, 2010.

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P7-17-1 Two cases of secondary adrenal insufficiency associated with unusual inflammatory complications:arthritis and meningitis

Masami Tanaka(1), (3), Yaeko Kondo(1), Takahide Itokazu(2), Satoshi Matsunaga(1), Hiroshi Ishii(1), Hiroshi Itoh(3)
(1)Department of Endocrinology, Tenri Hospital, (2)Department of Neurology, Tenri Hospital, (3)Department of Internal Medicine, School of Medicine, Keio University
ENDOCRINE JOURNAL 57 (suppl.2-2) S535-S535, 2010.

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P7-17-2 Analysis of GHRH-GH-IGF-1 axis in intrauterine growth retardation rats which did not show catch-up growth

Takahiro Nemoto, Tamotsu Shibasaki
Department of Physiology, Nippon Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S535-S535, 2010.

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P7-17-3 Chronic growth hormone administration increases insulin sensitivity in spontaneous dwarf rats

Hitoshi Sugihara, Akira Ishizaki, Toshiko Kano, Hideki Tamura, Shinichi Oikawa
Department of Medicine, Nippon Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S535-S535, 2010.

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P7-17-4 Role of Peptide YY(3-36)on growth hormone(GH)secretion in fasted male rats

Hideki Tamura, Toshiko Kano, Akira Ishizaki, Hitoshi Sugihara, Shinichi Oikawa
Department of Medicine, Nippon Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S536-S536, 2010.

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P7-17-5 Comparison of pituitary-adrenal responsiveness between insulin tolerance test and growth hormone-releasing peptide-2 test

Toshiko Kano(1), Hitoshi Sugihara(1), Akira Ishizaki(1), Hideki Tamura(1), Tamotsu Shibasaki(2), Shinichi Oikawa(1)
(1)Department of Medicine, Nippon Medical School, (2)Department of Physiology, Nippon Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S536-S536, 2010.

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P7-17-6 Effect of growth hormone releasing peptide-2 on ACTH and prolactin secretion in various hypothalamus and pituitary disease

Shinya Yamaguchi, Eiji Itagaki, Toshiaki Tanaka, Hirohisa Onuma, Hidenori Katsuta, Kazuto Takahashi, Tatsuhiro Shimoyama, Yoshikazu Sumitani, Michiko Kurokawa, Rie Moriya, Akiko Shida, Toshitaka Murashima, Susumu Nishida, Katsuhiko Yoshimoto, Hitoshi Ishida
The Third Department of Internal Medicine, Kyorin University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S536-S536, 2010.

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P7-17-7 Relationship between increased waist circumference and low serum total testosterone level rather than serum insulin-like growth factor-I in Korean male patients with hypopituitarism

Joo Young Kim, Eun Jig Lee
Department of Internal Medicine, Yousei University College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S536-S537, 2010.

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P7-17-8 The CXCR4 antagonist AMD3100 suppresses growth hormone production.

Daizo Yoshida, Kenta Koketshu, Akira Teramoto
Department of Neurosurgery, Nippon Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S537-S537, 2010.

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P7-18-1 Neuroendocrine regulatory peptides(NERPs)suppress presynaptic glutamatergic neurons and activate GABAergic interneurons to inhibit vasopressin secretion

Hideki Yamaguchi(1), Takeshi Saito(2), Kazuki Sasaki(3), Naoto Minamino(3), Yoichi Ueta(2), Masamitsu Nakazato(1)
(1)Department of Neurology, Respirology, Endocrinology and Metabolism, University of Miyazaki, (2)Department of Physiology, School of Medicine, University of Occupational and Environmental Health, (3)Department of Pharmacology, National Cardiovascular Center Research Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S537-S537, 2010.

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P7-18-2 Urocortin-3 transgenic mice display an anxiolytic-like behavior and an abnormal stress response

Mitsuru Nishiyama(1), Sarah C Coste(2), Malcolm J Low(3), Yasumasa Iwasaki(1), Shinya Makino(4), Kozo Hashimoto(5), Yoshio Terada(1), Mary P Stenzel-Poore(2)
(1)Department of Endocrinology, Metabolism & Nephrology, Kochi Medical School, (2)Department of Molecular Microbiology & Immunology, Oregon Health and Science University, (3)Vollum Institute, Oregon Health and Science University, (4)Department of Internal Medicine, Osaka Gyomeikan Hospital, (5)Department of Internal Medicine, Hosoki Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S537-S537, 2010.

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P7-18-3 Adrenocorticotropic tumor cells ransplanted into mouse embryos affected pancreatic histogenesis

Mai Kawamoto, Makiko Yamada, Jun Udagawa, Ryuju Hashimoto, Akihiro Matsumoto, Hiroki Otani
Department of Developmental Biology, Faculty of Medicine, Shimane University
ENDOCRINE JOURNAL 57 (suppl.2-2) S537-S538, 2010.

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P7-18-4 Sirt1 negatively regulates IGF-I production by growth hormone in hepatocytes

Masaaki Yamamoto(1), Genzo Iguchi(2), Hidenori Fukuoka(1), Michiko Takahashi(1), Hitoshi Nishizawa(1), Anastasia-Evi Handayaningsih(1), Yasuhiko Okimura(3), Hidesuke Kaji(4), Kazuo Chihara(5), Susumu Seino(1), (6), Yutaka Takahashi(1)
(1)Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, (2)Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Kobe University Hospital, (3)Department of Basic Allied Medicine, Kobe University School of Medicine, (4)Division of Physiology/metabolism, University of Hyogo, (5)Hyogo Prefectural Kakogawa Hospital, (6)Division of Cellular and Molecular Medicine, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S538-S538, 2010.

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P7-18-5 Effects of Prolactin-Releasing Peptide(PrRP)on the association of metabolism with stress

Akikazu Mochiduki, Zhifang Xu, Kinji Inoue
Faculty of Science and Engineering, Saitama University
ENDOCRINE JOURNAL 57 (suppl.2-2) S538-S538, 2010.

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P7-18-6 Participation of the prolactin-releasing peptide-containing neurons in caudal medulla in conveying hemorrhagic stress-induced signals to the paraventricular nucleus of the hypothalamus

Keiichi Itoi(1), (2), Katsuya Uchida(1), Gopal Das(1), Kinji Inoue(3), Tatsushi Onaka(4)
(1)Laboratory of Information Biology, Graduate School of Information Sciences, (2)Division of Neuroendocrinology, Graduate School of Medicine, Tohoku University, (3)Department of Regulatory Biology, Graduate School of Science and Engineering, Saitama University, (4)Department of Physiology, Juchi Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S538-S538, 2010.

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P7-18-7 Central control of body temperature by the osteoclast differentiation factors RANKL/RANK

Reiko Hanada(1), Andreas Leibbrandt(1), Shiho Kitaoka(2), Tomoyuki Furuyashiki(2), Hiroaki Fujihara(3), John Trichereau(1), Magdalena Paolino(1), Michael Bader(4), Hironobu Yoshimatsu(5), Sara Sebnem Kilic(6), Yoichi Ueta(3), Christian Pifl(7), Shuh Narumiya(2), Josef M.Penninger(1)
(1)Institute of Molecular Biotechnology of Austrian Academy of Science(IMBA), (2)Kyoto University Graduate School of Medicine, Department of Pharmacology, (3)Department of Physiology, School of Medicine, University of Occupational and Environmental Health, (4)Max Delbrueck Centre for Molecular Medicine, (5)Oita University Faculty of Medicine, (6)Uludag University Medical Faculty, (7)Medical University of Vienna, Center for Brain Research
ENDOCRINE JOURNAL 57 (suppl.2-2) S538-S539, 2010.

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P7-18-8 Effects of i.c.v.administration of RFamide related peptide-1 upon release of stress-related hormones and anxiety-related behavior

Maroost Keawwongse, Yuki Takayanagi, Tatsushi Onaka
Department of Physiology, Jichi Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S539-S539, 2010.

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P8-1-1 Immunolocalization of estrogen-related enzymes in benign human breast disorders

Yoshie Sasaki(1), Yoshiaki Onodera(2), Yasuhiro Miki(2), Jun-ichi Akahira(2), Hironobu Sasano(2), Takashi Suzuki(1)
(1)Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine, (2)Departments of Ananotmic Pathology, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S539-S539, 2010.

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P8-1-2 Regulation of oxytocin receptor by estrogen in rat uterus

Takuya Murata, Kazumi Narita, Toru Ichimaru, Takashi Higuchi
Department of Physiology, University of Fukui
ENDOCRINE JOURNAL 57 (suppl.2-2) S539-S539, 2010.

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P8-1-3 Protein and gene expression of progesteron and estrogen receptors are modified by xenoestrogen bisphenol a and its combination with estradiol

Maria Fickova, Ladislav Macho, Alzbeta Mlynarcikova
Institute of Experimental Endocrinology, Slovak Academy of Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S539-S539, 2010.

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P8-1-4 Regulation of estrogen receptor beta function by putative tumor suppressor DBC1

Satoshi Koyama(1), Osamu Hiraike(1), Shigeaki Kato(2), Tetsu Yano(1), Yuji Taketani(1)
(1)The Department of Obstetric and Gynecology, The University of Tokyo, (2)Institute of Molecular and Cellular Biosciences, The University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S539-S540, 2010.

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P8-1-5 Absence of ligand-independent transcriptional activation of the estrogen receptor via the estrogen response element in pituitary lactotrophs in primary culture

Maho Ishida, Tetsuo Mitsui, Michi Izawa, Jun Arita
Department of Physiology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi
ENDOCRINE JOURNAL 57 (suppl.2-2) S540-S540, 2010.

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P8-1-6 Hypoxia induces ER mRNA repression in MCF-7 cells

Young Joo Lee, K.H.Ryu, Y.S.Kim, J.W.Park
Department of Bioscience and Biotechnology College of Engineering, Institute of Biotechnology, Sejong University
ENDOCRINE JOURNAL 57 (suppl.2-2) S540-S540, 2010.

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P8-1-7 hSalvador and MST2 activate Estrogen receptor alpha

Young Joo Lee, Yeo Myeong Park, Won Chung Lim, Cho A Park
The Department of Bioscience and Biotechnology, University of Sejong
ENDOCRINE JOURNAL 57 (suppl.2-2) S540-S540, 2010.

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P8-1-8 Estrogen-responsive finger protein(Efp)as a therapeutic target for breast cancer utilizing DNA-modified small interfering RNA

Kazuya Ueyama(1), (2), Kazuhiro Ikeda(2), Wataru Satou(2), Kuniko Horie-Inoue(2), Satoru Takeda(1), Satoshi Inoue(2), (3)
(1)Department of Obstetrics and Gynecology, Juntendo University School of Medicine, (2)Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, (3)Departments of Geriatric Medicine and Anti-Aging Medicine, Graduate School of Medicine, The University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S540-S540, 2010.

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P8-1-9 Suppression of the transcriptional activity of estrogen receptor-alpha by thyroid transcription factor-2 in breast cancer cells

Eunsook Park, Keesook Lee
Chonnam National University
ENDOCRINE JOURNAL 57 (suppl.2-2) S541-S541, 2010.

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P8-2-1 Estrogen receptor alpha Pvull and Xbal gene polymorphisms and age-related changes in estradiol levels

Olga Ianas(1), Dana Manda(1), Lorand Savu(2), Susana Vladoiu(1), Oana Popa(1), Roxana Rosca(1), (3)
(1)National Institute of Endocrinology C.I.Parhon, (2)Genetic Lab SRL, (3)University of Medicine and Farmacy Carol Davila
ENDOCRINE JOURNAL 57 (suppl.2-2) S541-S541, 2010.

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P8-2-2 Estrogen receptors in human skin-its correlation with age and gender-

Takayoshi Inoue(1), (4), Yasuhiro Miki(1), Keiko Abe(1), Masahito Hatori(2), Masami Hosaka(2), Katsuhiko Ono(1), Miki Mori(1), Yoshiyuki Kariya(1), Setsuya Aiba(3), Hironobu Sasano(1)
(1)Department of Pathology, Tohoku University Graduate School of Medicine, (2)Departments of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, (3)Departments of Dermatology, Tohoku University Graduate School of Medicine, Miyagi, Japan Institution, (4)Biological Science Laboratories, Kao Corporation
ENDOCRINE JOURNAL 57 (suppl.2-2) S541-S541, 2010.

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P8-2-3 ERα expression influences estradiol and benzo[a]pyrine effects on lung adenocarcinoma tumor growth

Chun-Ju Lin, Susana Lin, Lih-Ann Li
Division of Environmental Health and Occupational Medicine, National Health Research Institutes
ENDOCRINE JOURNAL 57 (suppl.2-2) S541-S541, 2010.

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P8-2-4 The combination therapy of raloxifene chloride(RLX)and conjugated equine estrogen(CEE)for postmenopausal women-effect and safety

Miki Nakao, Manabu Nakazawa, Koji Kugu, Hajime Oishi, Tetsu Yano, Yuji Taketani
Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S542-S542, 2010.

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P8-2-5 Dienogest effective in treating hemorrhagic ascites due to endometriosis:A case report

Ryoko Asano, Hideya Sakakibara, Kayo Matsumoto, Tsuneo Nakazawa, Nao Matsumoto, Yasuko Suzuki, Fumiki Hirahara
Department of Obstetrics and Gynecology, Yokohama City University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S542-S542, 2010.

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P8-2-6 A novel synthetic androgen receptor ligand, S42, works as a selective androgen receptor modulator, and possesses metabolic effects with little impact on the prostate

Min Liu(1), (2), Toshihiko Yanase(2), (3), Tomoko Tanaka(2), (3), Ryoichi Takayanagi(2), Hajime Nawata(4)
(1)Department of Medical Biochemistry, Graduate School of Kyushu University, (2)Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, (3)Department of Endocrinology and Diabetes Mellitus, School of Medicine, Fukuoka University, (4)Graduate School of Medical Science, Kyushu University
ENDOCRINE JOURNAL 57 (suppl.2-2) S542-S542, 2010.

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P8-2-7 Phase I clinical trial of LGD-4033, a novel selective androgen receptor modulator(SARM)

Martin D.Meglasson(1), Ram Kapil(1), Mark T.Leibowitz(2), Joanna J.Peterkin(3), Yanling Chen(1), Kyoung-Jin Lee(1), Yong-Hee Lee(1), Eric G.Vajda(1)
(1)Ligand Pharmaceuticals, (2)CEDRA Clinical Research LLC, (3)Joanna J.Peterkin Consulting LLC
ENDOCRINE JOURNAL 57 (suppl.2-2) S542-S542, 2010.

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P8-2-8 High dose testosterone and intracytoplasmic sperm injection(ICSI)leading to successful treatment of infertility in a patient with partial androgen insensitivity syndrome(PAIS)due to a novel mutation in the androgen receptor

Karen M.Tordjman(1), Amnon Botchan(2), Arie Berkovitz(4), Serge Lumbroso(3)
(1)Institute of Endocrinology and Metabolism, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, (2)Institute for the Study of Fertility, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, (3)Service de Biochimie, Centre Hospitalier Universitaire, (4)Department of Obstetrics and Gynecology, Meir Hospital, Kfar Saba, Sackler Faculty of Medicine, Tel Aviv University
ENDOCRINE JOURNAL 57 (suppl.2-2) S543-S543, 2010.

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P8-2-9 Possible clinical manifestations of androgen resistance

Anastasiya E.Hlazkova(1), Viacheslau I.Vashula(1), Serhey Nikanovich(1), Volha V.Zhukovskaya(2)
(1)Belarussian Medical Academy of Post-Graduate Education, (2)Belarussain State Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S543-S543, 2010.

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P8-3-1 Glucocorticoid induces expression of astrocyte marker GFAP mRNA in mouse neural stem cells

Jun Kanno(1), (2), Katsuhide Igarashi(1), Kentaro Tanemura(1), Hirotugu Asano(2), Kinichi Nakashima(2)
(1)Divison of Cellular and Molecular Toxicology, National Institute of Health Sciences, (2)Laboratory of Molecular Neuroscience, Graduate School of Biological Sciences, Nara Institute of Science and Technology
ENDOCRINE JOURNAL 57 (suppl.2-2) S543-S543, 2010.

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P8-3-2 Crosstalk between glucocorticoid response and nutritional sensor in skeletal muscle

Noriaki Shimizu(1), Noritada Yoshikawa(1), (2), Naoki Ito(3), Yusuke Tagata(4), Kenji Takehana(4), Takako Maruyama(1), Yuko Suzuki(3), Shin'ichi Takeda(3), Chikao Morimoto(1), (2), Hirotoshi Tanaka(1), (2)
(1)Division of Clinical Immunology, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, (2)Research Hospital, Institute of Medical Science, University of Tokyo, (3)Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, (4)Pharmaceutical Research Laboratories, Ajinomoto Co.Inc
ENDOCRINE JOURNAL 57 (suppl.2-2) S543-S543, 2010.

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P8-3-3 Glucocorticoid receptor plays an indispensable role in mineralocorticoid receptor-dependent transcription/role of GR in MR-dependent transcription

Makoto Tsugita(1), Yasumasa Iwasaki(1), Mitsuru Nishiyama(1), Takafumi Taguchi(1), Masayuki Shinahara(1), Yoshinori Taniguchi(1), Mizuho Okazaki(1), Shuichi Nakayama(1), Machiko Kambayashi(1), Toshihiro Takao(1), Akira Nishiyama(2), Elise P.Gomez-Sanchez(3), Kozo Hashimoto(1), Yoshio Terada(1)
(1)Department of Endocrinology, Metabolism, and Nephrology, Kochi Medical School, Kochi University, (2)Department of Pharmacology, Faculty of Medicine, Kagawa University, (3)Division of Endocrinology, Department of Medicine, G.V.Montgomery VA Medical Center and University of Mississippi Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S544-S544, 2010.

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P8-3-4 Non-coding RNA Gas5 is a growth arrest/starvation-associated repressor of the glucocorticoid receptor

Tomoshige Kino(1), Darrell E.Hurt(2), Takamasa Ichijo(1), Nancy Nader(1), George P.Chrousos(3)
(1)Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shirver National Institute of Child Health and Human Development, (2)Bioinformatics and Scientific IT Program, Office of Technology Information Systems, National Institute of Allergy and Infectious Diseases, (3)First Department of Pediatrics, Athens University Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S544-S544, 2010.

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P8-3-5 Aldosterone induces renal senescence in proximal tubular cells via mineralocorticoid receptor/p21-dependent pathway

Daisuke Nakano(1), Yu-Yan Fan(2), Masakazu Kohno(2), Hirofumi Hitomi(1), Robin Felder(3), Akira Nishiyama(1)
(1)Department of Pharmacology, Kagawa University, (2)Department of Cardiorenal and Cerebrovascular Medicine, Kagawa University, (3)Department of Pathology, University of Virginia
ENDOCRINE JOURNAL 57 (suppl.2-2) S544-S544, 2010.

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P8-3-6 New aspect of calcium channel blockers:How azelnidipine inhibits mineralocorticoid receptor activity

Wakako Kawarazaki, Miki Nagase, Kenichi Ishizawa, Maki Takeuchi, Shigetaka Yoshida, Shigeru Shibata, Toshiro Fujita
Department of Nephrology and Endocrinology, University of Tokyo Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S544-S544, 2010.

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P8-3-7 Mineralocorticoid receptor activation increases salt induced renal injury in young rats

Hiroo Kawarazaki, Katsuyuki Ando, Megumi Fujita, Toshiro Fujita
Department of Nephrology and Endocrinology, University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S545-S545, 2010.

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P8-3-8 Gene expression of mineralocorticoid receptor is affected by M1/M2 polarization stimuli in rat peritoneal macrophages

Kenichi Ishizawa, Miki Nagase, Shigetaka Yoshida, Shigeru Shibata, Wakako Kawarazaki, Maki Takeuchi, Toshiro Fujita
Department of Nephrology and Endocrinology, University of Tokyo Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S545-S545, 2010.

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P8-3-9 Functional analysis of a novel MR co-activator P120

Kenichi Yokota(1), Fumiaki Ohtake(1), Shigeaki Kato(1), (2)
(1)Laboratory of Nuclear Signaling, Institute of Molecular and Cellular Biosciences, The University of Tokyo, (2)Japan Science and Technology Agency, ERATO
ENDOCRINE JOURNAL 57 (suppl.2-2) S545-S545, 2010.

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P8-4-1 Cholesterol sulfate regulation of profilaggrin expression:Studies involving sirna for SULT2B1B and ROR alpha in primary cultures of normal human epidermal keratinocytes

Osamu Hanyu(1), Hirotoshi Fuda(3), Yuko Higashi(3), Motohiro Endo(3), Hanako Nakae(3), Atsushi Kohjitani(3), Takashi Miida(2), Yoshifusa Aizawa(1), Charles A.Strott(3)
(1)Division of Endocrinology and Metabolism, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, (2)Department of Clinical Laboratory Medicine, Juntendo University School of Medicine, (3)Section on Steroid Regulation, the Endocrinology and Reproduction Research Branch, National Institute of Child Health and Human Development, National Institutes of Health
ENDOCRINE JOURNAL 57 (suppl.2-2) S545-S546, 2010.

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P8-4-2 Co-agonism of peroxisome proliferator-activated receptors-thiazolidinediones, fibrates and telmisartan-

Tetsuya Tagami, Hiroyuki Yamamoto, Kenji Moriyama, Takeshi Usui, Akira Shimatsu, Mitsuhide Naruse
Clinical Research Institute, Kyoto Medical Center, National Hospital Organization
ENDOCRINE JOURNAL 57 (suppl.2-2) S546-S546, 2010.

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P8-4-3 Mitotane potentially causes drug-drug interactions through activation of intestinal SXR/PXR

Akira Takeshita(1), Junko Igarashi-Migitaka(2), Noriyuki Koibuchi(3), Yasuhiro Takeuchi(1)
(1)Department of Endocrinology and Metabolism, Toranomon Hospital and Okinaka Memorial Institute for Medical Research, (2)Department of Anatomy and Cell Biology, St.Marianna University School of Medicine, (3)Department of Integrative Physiology, Gunma University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S546-S546, 2010.

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P8-4-4 Ligand-based gene expression profiling reveals novel roles of glucocorticoid receptor in the cardiomyocytes

Noritada Yoshikawa(1), (2), Motoaki Sano(3), Satori Tokudome(3), Noriaki Shimizu(1), Takako Maruyama(1), Masao Nagasaki(4), Seiya Imoto(4), Satoru Miyano(4), Yusuke Tagata(5), Shinobu Nishitani(5), Kenji Takehana(5), Keiichi Fukuda(3), Chikao Morimoto(1), (2), Hirotoshi Tanaka(1), (2)
(1)Division of Clinical Immunology, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, (2)Department of Rheumatology and Allergy, Research Hospital, Institute of Medical Science, University of Tokyo, (3)Department of Regenerative Medicine and Advanced Cardiac Therapeutics, Keio University School of Medicine, (4)Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, University of Tokyo, (5)Pharmaceutical Research Laboratories, Ajinomoto Co.Inc
ENDOCRINE JOURNAL 57 (suppl.2-2) S546-S546, 2010.

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P8-4-5 The role of the hydrophobic core from helices 6 and 7 in the selective ligand-nuclear receptor interactions

Ferdinand Molnar
Department of Pharmaceutics, University of Kuopio
ENDOCRINE JOURNAL 57 (suppl.2-2) S546-S546, 2010.

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P8-4-6 Positive regulation of spondin 2 by thyroid hormone is associated with cell migration and invasion

Kwang-Huei Lin, Chen-Hsin Liao, Shih-Chi Yeh, Ya-Hui Huang
The Department of Biochemistry, Chang Gung University
ENDOCRINE JOURNAL 57 (suppl.2-2) S547-S547, 2010.

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P8-4-7 Human testicular orphan receptor 4 enhances thyroid hormone receptor signaling

Ya-Hui Huang(1), Kwang-Huei Lin(2)
(1)Chang Gung Memorial Hospital, (2)Chang Gung University
ENDOCRINE JOURNAL 57 (suppl.2-2) S547-S547, 2010.

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P8-4-8 Alpha-Melanocyte Stimulating Hormone markedly induces IL-6 expression in adipocytes:Investigating the role of the nuclear hormone receptor 4A subgroup

Shu-Ching M.Wang, Stephen Myers, Natalie Eriksson, George E.O.Muscat
Institute for Molecular Bioscience, University of Queensland
ENDOCRINE JOURNAL 57 (suppl.2-2) S547-S547, 2010.

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P8-4-9 Nuclear O-glycosylation of a histone methyltransferase facilitates RA-induced transcription and differentiation

Ryoji Fujiki, Toshihiro Chikanishi, Waka Hashiba, Robert G Roeder, Hirochika Kitagawa, Shigeaki Kato
Nuclear Signaling, IMCB, The university of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S547-S547, 2010.

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P8-5-1 Estrogen-related receptor γ modulates adipogenesis-related gene expression during adipocytic differentiation

Mayumi Kubo(1), Nobuhiro Ijichi(2), Kazuhiro Ikeda(2), Kuniko Horie-Inoue(2), Satoru Takeda(1), Satoshi Inoue(2), (3)
(1)Department of Obstetrics and Gynecology, Juntendo University School of Medicine, (2)Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, (3)Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S548-S548, 2010.

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P8-5-2 Expession of estrogen receptor(ER)beta in murine embryonic stem cells

Tomoko Shoda, Shuji Hirata, Kazuhiko Hoshi
Department of Obstetrics and Gynecology, Interdisciplinary Graduate School of Medicine and Engineering, University fo Yamanashi
ENDOCRINE JOURNAL 57 (suppl.2-2) S548-S548, 2010.

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P8-5-3 Androgen and estrogen receptors triple knockout mice to evaluate biological impact on sex steroids hormones actions

Takahiro Matsumoto(1), (2), N.Tsuji(1), K.Inoue(1), S.Kondo(1), Yoko Yamamoto(1), Y.Okuno(1), (2), T.Sato(1), Shigeaki Kato(1), (2)
(1)Laboratory of Nuclear Signaling, Institute of Molecular and Cellular Biosciences, University of Tokyo, (2)ERATO, Japan Science and Technology Agency
ENDOCRINE JOURNAL 57 (suppl.2-2) S548-S548, 2010.

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P8-5-4 Lobe differences and tissue specific androgen regulation of 5α-Reductase type 2 and intraprostatic DHT levels in mouse prostate

Keely M.McNamara, David T.Harwood, Ulla Simanainen, David J.Handelsman
Andrology Labratory, ANZAC Research Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S548-S548, 2010.

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P8-5-5 Ah receptor acts as a ligand-dependent ubiquitin ligase

Fumiaki Ohtake(1), (2), Yoshiaki Fujii-Kuriyama(1), Shigeaki Kato(1), (2)
(1)Institute of Molecular and Cellular Biosciences, University of Tokyo, (2)ERATO, Japan Science and Technology Agency
ENDOCRINE JOURNAL 57 (suppl.2-2) S548-S549, 2010.

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P8-5-6 A tissue-specific function by unliganded VDR

Yoko Yamamoto(1), Ai Memezawa(1), Ken-ichiro Takagi(2), Eiji Ochiai(2), Shigeaki Kato(1), (3)
(1)IMCB, The University of Tokyo, (2)Teijin Pharma Limited, (3)ERATO, JST
ENDOCRINE JOURNAL 57 (suppl.2-2) S549-S549, 2010.

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P8-5-7 Epidermal growth factor enhances mineralocorticoid receptor transactivation via deubiquitylation of the receptor

Yuko Mitsuishi, Hirotaka Shibata, Isao Kurihara, Kenichi Yokota, Ayano Murai-Takeda, Rie Jo, Takeshi Hayashi, Yuichiro Motosugi, Hiroshi Itoh
Department of Internal Medicine, School of Medicine, Keio University
ENDOCRINE JOURNAL 57 (suppl.2-2) S549-S549, 2010.

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P8-5-8 Corticotropin-Releasing Hormone(CRH)transgenic mice show hyperphagia with increased agouti-related protein mRNA in the arcuate nucleus

Shuichi Nakayama(1), Mitsuru Nishiyama(1), Yasumasa Iwasaki(1), Mizuho Okazaki(1), Masayuki Shinahara(1), Takafumi Taguchi(1), Shinya Makino(2), Kozo Hashimoto(3), Yoshio Terada(1)
(1)Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, (2)Department of Internal Medicine, Osaka Gyomeikan Hospital, (3)Department of Internal Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S549-S549, 2010.

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P9-1-1 Myocardin-related transcription factor-A, a Rho-dependent co-factor of serum response factor, is a common mediator for mechanical stretch-and neurohumoral stimulation-induced increase in BNP gene transcription

Koichiro Kuwahara, Yoshihiro Kuwabara, Hideyuki Kinoshita, Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S549-S550, 2010.

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P9-1-2 Transgenic MSH overexpression improves vascular function and protects the heart against hypertrophy

Petteri Rinne(1), (2), Antti Saraste(3), Suvi T.Ruohonen(1), Saku Ruohonen(1), Eriika Savontaus(1), (4)
(1)Department of Pharmacology, Drug development and Therapeutics, University of Turku, (2)Drug Discovery Graduate School, University of Turku, (3)Department of Medicine, Turku University Hospital, (4)Clinical Pharmacology, TYKSLAB, Health Care District of Southwest Finland
ENDOCRINE JOURNAL 57 (suppl.2-2) S550-S550, 2010.

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P9-1-3 Natriuretic peptides/cGMP-dependent protein kinase cascades promote mitochondrial biogenesis in muscle and prevent obesity

Kazutoshi Miyashita(1), Hiroshi Itoh(1), Hirokazu Tsujimoto(2), Naohisa Tamura(2), Yasutomo Fukunaga(2), Masakatsu Sone(2), Kenichi Yamahara(2), Daisuke Taura(2), Megumi Inuzuka(2), Takuhiro Sonoyama(2), Kazuwa Nakao(2)
(1)Department of Internal Medicine, School of Medicine, Keio University, (2)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S550-S550, 2010.

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P9-1-4 Therapeutic potential of brain natriuretic peptide for liver fibrosis

Takuhiro Sonoyama, Naohisa Tamura, Kazutoshi Miyashita, Kwijun Park, Naofumi Oyamada, Daisuke Taura, Megumi Inuzuka, Katsutoshi Kojima, Kyoko Honda, Yasutomo Fukunaga, Masakatsu Sone, Akihiro Yasoda, Hiroshi Arai, Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S550-S550, 2010.

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P9-1-5 Lack of natriuretic peptide action aggravates insulin resistance and hypertension linked to diet-induced obesity in mice

Hisashi Makino(1), Takeshi Tokudome(2), Ichiro Kishimoto(1), Yoshihiro Miyamoto(1), Yuhei Kawano(3), Kazuwa Nakao(4), Yasunao Yoshimasa(1), Kenji Kangawa(2)
(1)Department of Atherosclerosis and Diabetes, National Cardiovascular Center, (2)National Cardiovascular Center Research Institute, (3)Department of Nephrology and Hypertension, National Cardiovascular Center, (4)Departemnt of Endocrinology and Metabolism, Kyoto University Graduate School
ENDOCRINE JOURNAL 57 (suppl.2-2) S551-S551, 2010.

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P9-1-6 Plasma B-type natriuretic peptide level is valid tool for cardiovascular risk stratification in diabetes subjects

Motoyuki Nakamura(1), Toshie Segawa(1), Fumitaka Tanaka(1), Tomohiro Takahashi(1), Yorihiko Koeda(1), Masafumi Sakuma(1), Toshiyuki Onoda(1), Kazuyoshi Itai(1), Masaki Ohsawa(1), Kozo Tanno(1), Kiyomi Sakata(1), Yuki Yoshida(1), Kazuko Kawamura(2), Akira Okayama(3)
(1)Department of Internal Med, Iwate Medical University, (2)Iwate Health Service Association, (3)Japan Anti-Tuberculosis Association
ENDOCRINE JOURNAL 57 (suppl.2-2) S551-S551, 2010.

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P9-1-7 N-terminal pro B-type natriuretic peptide levels are associated with sex hormone-ninding globulin in peri-and postmenopausal women

Sumika Matsui, Toshiyuki Yasui, Ayako Saijo, Hirokazu Uemura, Satoshi Yamamoto, Minoru Irahara
Department of Obstetrics and Gynecology, The University of Tokushima Graduate School
ENDOCRINE JOURNAL 57 (suppl.2-2) S551-S551, 2010.

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P9-1-8 Therapeutic significance of atrial natriuretic peptide on peripheral arterial disease

Kwijun Park(1), Hiroshi Itoh(2), Kenichi Yamahara(2), Kazutoshi Miyashita(2), Naofumi Oyamada(1), Naoya Sawada(1), Daisuke Taura(1), Megumi Inuzuka(1), Takuhiro Sonoyama(1), Hirokazu Tsujimoto(1), Yasutomo Fukunaga(1), Naohisa Tamura(1), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Internal Medicine, Keio University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S551-S552, 2010.

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P9-1-9 Successful treatment of a case with post-ischemic, oliguric acute kidney injury with low-dose atrial natriuretic peptide and massive fluid infusion

Akira Ishii(1), Kiyoshi Mori(1), Masashi Mukoyama(1), Shuma Taguchi(2), Masato Kasahara(2), Hideki Yokoi(1), Kenji Kawada(2), Akinari Nomura(2), Yoshiharu Sakai(2), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Surgery, Graduate School of Medicine, Kyoto University
ENDOCRINE JOURNAL 57 (suppl.2-2) S552-S552, 2010.

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P9-2-1 Prognosis of hypertension and renal dysfunction in patients with primary aldosteronism:comparison of unilateral adrenalectomy and medical therapy

Yuichiro Motosugi, Hirotaka Shibata, Isao Kurihara, Kazutoshi Miyashita, Ayano Murai-Takeda, Yuko Mitsuishi, Rie Jo, Hiroshi Itoh
Department of Internal Medicine, School of Medicine, Keio University
ENDOCRINE JOURNAL 57 (suppl.2-2) S552-S552, 2010.

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P9-2-2 Recommendation of adrenal venous sampling before surgical treatments for the patients of primary aldosteronism with adrenal nodules on CT:the differential diagnosis of 329 patients with primary aldosteronism in comparison with their computed tomographic findings

Fumitoshi Satoh(1), Ryo Morimoto(1), Masataka Kudo(1), Yoshinori Iwakura(1), Osamu Murakami(1), Kei Takase(2), Shoki Takahashi(2), Yoichi Arai(3), Yoshihiro Nakamura(4), Takashi Suzuki(4), Hironobu Sasano(4), Sadayoshi Ito(1)
(1)Nephrology, Endocrinology and Vascular Medicine, Tohoku University Hospital, (2)Radiology, Tohoku University Hospital, (3)Urology, Tohoku University Hospital, (4)Pathology, Tohoku University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S552-S552, 2010.

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P9-2-3 Aldosterone breakthrough during combination therapy with angiotensin II receptor blocker and low dose diuretic in hypertensive patients with diabetes mellitus

Takashi Yoneda, Yoshiyu Takeda, Shigehiro Karashima, Masashi Demura, Mikiya Usukura, Hiroyuki Takata, Nobushige Oda, Yasuhiro Yamamoto, Atsushi Hashimoto, Shunsuke Mori, Mitsuhiro Kometani, Masashi Ooe, Masakazu Yamagishi
Department of Internal Medicine, Graduate School of Medical Science, Kanazawa University
ENDOCRINE JOURNAL 57 (suppl.2-2) S552-S553, 2010.

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P9-2-4 Effects of olmesartan administration on renin-angiotensin system in hypertensive patients with diabetes mellitus

Naoki Hiroi(1), Aya Yoshihara(1), Mariko Sue(1), Ryo Iga(1), Rika Shigemitsu(1), (2), Natsumi Masai(1), Gen Yoshino(1)
(1)Division of Diabetes, Metabolism and Endocrinology, Toho University, (2)Department of Internal Medicine, Kawasaki Social Insurance Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S553-S553, 2010.

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P9-2-5 Aldosterone inhibits endothelial morphogenesis and angiogenesis through the downregulation of peroxisome proliferator activated receptor-gamma and subsequent vascular endothelial growth factor receptor-2 expression

Miki Fujii, Isao Inoki, Satoru Inaba, Tadashi Konoshita, Isamu Miyamori
The Third Department of Internal Medicine, University of Fukui
ENDOCRINE JOURNAL 57 (suppl.2-2) S553-S553, 2010.

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P9-2-6 A case of pseudo-hypoaldosteronism type 2

Kaori Ikebukuro(1), Masako Hatano(1), Miho Senda(1), Akinobu Minagawa(1), Tsuneo Takenaka(3), Shinichi Uchida(2), Takuya Awata(1), Shigehiro Katayama(1)
(1)Department of Endocrinology and Metabolism, Faculty of Medicine, School of Medicine, Saitama Medical University, (2)Department of Nephrology, Faculty of Medicine, Tokyo Medical and Dental University, (3)Department of Nephrology, Faculty of Medicine, School of Medicine, Saitama Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S553-S553, 2010.

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P9-2-7 Aldosterone and androgens as informative biomarkers of metabolic syndrome(MS)in young overweight patients

Nikolai P.Goncharov(1), Gulinara V.Katsya(1), Galina S.Kolesnikova(1), Svetlana A.Butrova(1), Farid Saad(2)
(1)Department of Biochemical Endocrinology and Hormonal Analysis, Endocrinology Research Center, (2)Schering AG
ENDOCRINE JOURNAL 57 (suppl.2-2) S553-S554, 2010.

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P9-2-8 Aldosterone synthase(CYP11B2)C-344T polymorphism affects the association of age-related changes of the serum C-reactive protein

Kenji Oki, Tsuguka Shiwa, Takako Asao, Takafumi Sugihiro, Yu Sakashita, Yoshiaki Oda, Tomokazu Awaya, Shuhei Nakanishi, Kiminori Yamane, Nobuoki Kohno
The Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University
ENDOCRINE JOURNAL 57 (suppl.2-2) S554-S554, 2010.

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P9-3-1 Telmisartan inhibits cytokine-induced nuclear factor-kappa B activation independently of the peroxisome proliferator-activated receptor-gamma

Ayuko Nakano, Yoshiyuki Hattori, Chie Aoki, Atsuko Tomizawa, Teruo Jojima, Yoshiaki Kawagoe, Hiroyuki Kase, Kikuo Kasai
Dokkyo University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S554-S554, 2010.

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P9-3-2 A selective PPARγ modulating angiotensin II receptor blockade regulates mitochondrial biogenesis in skeletal muscle

Ken Sugimoto, Tomomi Fujisawa, Nobuyasu Shindo, Xiang Wang, Mitsuru Ohishi, Hiromi Rakugi
Geriatric Medicine, Osaka University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S554-S554, 2010.

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P9-3-3 Irbesartan improves hyperlipidemia with activated hepatic expression of peroxisome proliferator-activated receptor alpha target genes in of Koletsky obese rats

Xianglu Rong, Yuhao Li, Ken Ebihara, Mingming Zhao, Toru Kusakabe, Tsutomu Tomita, Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto University Graduate School
ENDOCRINE JOURNAL 57 (suppl.2-2) S554-S555, 2010.

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P9-3-4 Safety of metformin administration to patients with diabetes mellitus type 2 and myocardial infarction in the anamnesis

Anastasiya E.Hlazkova, Natalia A.Yaroshevich, Larissa I.Danilova, Irina I.Burko, Valentina I.Shutova
Belarussain Medical Academy of Post-Graduate Education
ENDOCRINE JOURNAL 57 (suppl.2-2) S555-S555, 2010.

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P9-3-5 Fasting serum glucose level and mortality from ischemic heart disease and stroke subtypes

Song Vogue Ahn, Hyeon Chang Kim, Chung Mo Nam, Il Suh
Department of Preventive Medicine, Yonsei University College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S555-S555, 2010.

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P9-3-6 Association of Glycated Hemoglobin with metabolic syndrome in nondiabetic

Myung Ha Lee, Song Vogue Ahn, Hyeon Chang Kim, Il Suh
Department of Preventive Medicine, Yonsei University
ENDOCRINE JOURNAL 57 (suppl.2-2) S555-S555, 2010.

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P9-3-7 Mechanisms of regulation of insulin action by insulin-like growth factor-1 receptor

Neha Garg, Sachin Thakur, Martin L.Adamo
University of Texas Health Science Centre at San Antonio
ENDOCRINE JOURNAL 57 (suppl.2-2) S555-S556, 2010.

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P9-3-8 Function of adipose differentiation-related protein(ADRP)in myocardial steatosis

Jinya Suzuki(1), Masami Ueno(2), Tomoko Kimura(1), Michiko Imagawa(1), Yasuo Zenimaru(2), Sadao Takahashi(1), Shoichiro Ikuyama(3), Fredric B Kraemer(2), Isamu Miyamori(1)
(1)The Third Department of Internal Medicine, University of Fukui, (2)Endocrinology, Stanford University School of Medicine, (3)Kyushu University Medical Institute of Bioregulation
ENDOCRINE JOURNAL 57 (suppl.2-2) S556-S556, 2010.

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P9-4-1 Cardiovascular risk factors and arterial rigidity are similar in asymptomatic normocalcemic and hypercalcemic primary hyperparathyroidism

Karen M.Tordjman, Marianna Yaron, Elena Izkhakov, Etty Osher, Galina Shenkerman, Naftali Stern
Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University
ENDOCRINE JOURNAL 57 (suppl.2-2) S556-S556, 2010.

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P9-4-2 Cardiovascular risk factors before and after parathyroidectomy in primary hyperparathyroidism

Avi Wilder(1), Avraham Ishay(2), Paula Herer(2), Rafael Luboshitzky(2)
(1)E.N.T Dept.HA-EMEK Medical Center, (2)Endocrine Institute, Ha Emek Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S556-S556, 2010.

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P9-4-3 What kinds of patients should undergo coronary computed tomography as screening for coronary artery disease?

Shin-ichiro Miura, Ryoko Mitsutake, Yuhei Shiga, Yoshinari Uehara, Keijiro Saku
Department of Cardiology, Fukuoka University
ENDOCRINE JOURNAL 57 (suppl.2-2) S556-S557, 2010.

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P9-4-4 Significance of serum high-density lipoprotein cholesterol levels for diagnosis of coronary stenosis as determined by mdct in patients with suspected coronary artery disease

Shin-ichiro Miura, Ryoko Mitsutake, Yuhei Shiga, Yoshinari Uehara, Keijiro Saku
Department of Cardiology, Fukuoka University
ENDOCRINE JOURNAL 57 (suppl.2-2) S557-S557, 2010.

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P9-4-5 Metabolic parameters in patients with primary hyperparathyroidism

Goran Cvijovic, Dragan Micic, Aleksandra Kendereski, Svetlana Zoric, Mirjana Sumarac, Danica Stamenkovic-Pejkovic, Danka Jeremic
Institute of Endocrinology, Diabetes and Diseases of metabolism, Clinical Center of Serbia
ENDOCRINE JOURNAL 57 (suppl.2-2) S557-S557, 2010.

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P9-4-6 Improvement of insulin sensitivity after radical treatment of primary hyperparathyroidism

Aleksandra Kendereski, Dragan Micic, Goran Cvijovic, Sveltlana Zoric, Mirjana S.Sumarac-Dumanovic, Danica Stamenkovic-Pejkovic, Danka Jeremic
Institute of Endocrinology, Diabetes and Diseases of metabolism, Clinical Center of Serbia
ENDOCRINE JOURNAL 57 (suppl.2-2) S557-S557, 2010.

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P9-4-7 Cardiovascular risk in patients with metabolic syndrom associating hypothyroidism

Eduard Circo(1), Marian Beciu(2), Razvan Circo(3)
(1)Endocrinology Department, Ovidius University Constanta, (2)County Ambulance Service Constanta, (3)Carol Davila University of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S557-S557, 2010.

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P9-4-8 Effusive constrictive periarditis possibly caused by infection in a patient with hyperthyroidism

Chinatsu Yamada, Koichiro Kuwahara, Masako Miura, Yuko Yamada, Takeya Minami, Yoshihiro Kuwabara, Masataka Fujiwara, Hideyuki Kinoshita, Satoru Usami, Yasuaki Nakagawa, Kazuma Nakao
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S558-S558, 2010.

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P9-5-1 Pulse'treatment with high-dose angiotensin receptor blocker(ARB)causes regression of hypertension in SHRmcr-cp rats with metabolic syndrome

Kimiko Ishiguro, Hiroyuki Sasamura, Kaori Hayashi, Yusuke Sakamaki, Tatsuhiko Azegami, Hiroshi Itoh
Department of Internal Medicine, Keio University
ENDOCRINE JOURNAL 57 (suppl.2-2) S558-S558, 2010.

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P9-5-2 Chronic angiotensin II infusion suppresses renal expression of angiotensin II type 1 receptor-interacting molecule ATRAP to decrease angiotensin II type 1 receptor internalization

Kouichi Tamura(1), Hiromichi Wakui(1), Miyuki Matsuda(1), Toru Dejima(1), Atsu-ichiro Shigenaga(1), Shin-ichiro Masuda(1), Koichi Azuma(1), Akinobu Maeda(1), Tomohiko Kanaoka(1), Masato Ohsawa(1), Tomonori Hirose(2), Tomoaki Ishigami(1), Yoshiyuki Toya(1), Machiko Yabana(1), Satoshi Umemura(1)
(1)Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, (2)Department of Molecular Biology, Yokohama City University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S558-S558, 2010.

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P9-5-3 Long-term treatment with handle region peptide inhibits the development of glomerulosclerosis in the non-clipped kidney of two-kidneys, one-clip Goldblatt hypertension

Masaki Ryuzaki(1), Atsuhiro Ichihara(2), Yoichi Oshima(1), Mariyo Sakoda(1), Asako Kurauchi-Mito(1), Tatsuya Narita(1), Kenichiro Kinouchi(1), Kanako Bokuda(1), Akira Nishiyama(3), Hiroshi Itoh(1)
(1)Department of Internal Medicine, Keio University School of Medicine, (2)Endocrinology & Anti-Aging Medicine, Keio University School of Medicine, (3)Pahramacology, Kagawa University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S558-S559, 2010.

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P9-5-4 Soluble form of the(Pro)renin receptor in plasma

Nobuyoshi Mori(1), Takuo Hirose(2), Kazuhito Totsune(2), (3), Bin Xu(1), Rong Rong(1), Daisuke Ito(1), Kenta Takashima(1), Yoshikazu Muroya(1), Fumika Suzuki(1), Makoto Nagasaka(1), Satoru Ebihara(1), Osamu Ito(1), Kazuhiro Takahashi(4), Yutaka Imai(2), (3), Masahiro Kohzuki(1)
(1)Department of Internal Medicine and Rehabilitation Science, Tohoku University graduate School of Medicine, (2)Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate school of Pharmaceutical Sciences and Medicine, (3)Tohoku University 21st Century Center of Excellence Program "Comprehensive Research and Education Center for Planning of Drug Development and Clinical Evaluation(CRESCENDO)", (4)Department of Endocrinology and Applied Medical Science, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S559-S559, 2010.

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P9-5-5 Direct renin inhibitor prevents leukocyte recruitment to mouse femoral artery via blood pressure-independent, MAP kinases-and NFkB-dependent mechanisms

Masayuki Yoshida(1), Jun Ino(1), (2), Chiari Kojima(2), Kosaku Nitta(2)
(1)Life Science and Bioethics Research Center, Tokyo Medical and Dental University, (2)Department of Internal Medicine, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S559-S559, 2010.

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P9-5-6 Direct renin measurement:Performances of a fully automated assay and compatibility with daily practice

Damien Gruson(1), Dominique Maiter(2), Alexandre Persu(3)
(1)Department of Endocrine Biology, St-Luc University Clinic, (2)Department of Endocrinology, St-Luc University Clinic, (3)Department of Cardiology, St-Lur University Clinic
ENDOCRINE JOURNAL 57 (suppl.2-2) S559-S559, 2010.

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P9-5-7 Angiotensin II accelerates the progression of renovascular diseases by enhancing cellular senescence:Analysis using human ES cell-derived smooth muscle cells

Takahiko Nishi(1), Kenichi Yamahara(1), (2), Toshiaki Monkawa(1), Koichiro Homma(1), Shintaro Yamaguchi(1), Ryuji Morizane(1), Sizuka Hujii(1), Sonoko Takesue(1), Hiroshi Itoh(1)
(1)Department of Internal Medicine, Keio University, (2)National Cardiovascular Center Research Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S559-S560, 2010.

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P9-5-8 Local cardiac angiotensin system in the developmental origins of cardiovascular disorders

Hiroaki Itoh(3), Makoto Kawamura(2), Shigeo Yura(2), Norimasa Sagawa(3), Naohiro Kanayama(1)
(1)Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, (2)Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, (3)Department of Obstetrics and Gynecology, Mie University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S560-S560, 2010.

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P9-6-1 Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in metabolic syndrome

Megumi Fujita, Katsuyuki Ando, Hiroo Kawarazaki, Toshiro Fujita
Department of Nephrology and Endocrinology, Faculty of Medicine, The University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S560-S560, 2010.

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P9-6-2 Oxidative stress/Rac1 mediates mineralocorticoid receptor activation and resultant left ventricular diastolic dysfunction

Tatsuo Shimosawa(1), Hong Wang(2), Yuzaburo Uetake(2), Shengyu Mu(2), Yanan Shi(1), Fumiko Mori(2), Yutaka Yatomi(1), Toshiro Fujita(2)
(1)Dept of Clinical Lab, University of Tokyo, (2)Dept of Endocrinology and Nephrology, University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S560-S560, 2010.

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P9-6-3 High glucose enhances glucocorticoid-induced cardiomyocyte mineralocorticoid receptor activation through oxidative stress

Tatsuo Shimosawa(1), Hong Wang(2), Fumiko Mori(2), Shengyu Mu(2), Yuzaburo Uetake(2), Yanan Shi(1), Yutaka Yatomi(1), Toshiro Fujita(2)
(1)Dept of Clinical Lab, University of Tokyo, (2)Dept of Endocrinology and Nephrology, University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S560-S561, 2010.

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P9-6-4 The role of angiotensin converting enzyme 2 and angiotensin 1-7 stimulated by oxidative stress in vitro

Mitsuru Ohishi, Koichi Yamamoto, Norihiro Hayashi, Atsushi Shiota, Yuji Tatara, Masao Takeda, Yoshihiro Iwamoto, Hiromi Rakugi
Department of Geriatric Medicine, Osaka University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S561-S561, 2010.

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P9-6-5 Dehydroepiandrosterone sulfate is an endothelial function-independent anti-atherogenic factor

Sumiko Yoshida(1), Ken-ichi Aihara(1), Yuka Ueda(1), Kiyoe Kurahashi(1), Mizuho Kinouchi(1), Itsuro Endo(1), Yuichi Fujinaka(1), Takashi Iwase(2), Masashi Akaike(2), Masataka Sata(2), Toshio Matsumoto(2)
(1)Department of Medicine and Bioregulaotry Sciences, The University of Tokushima, (2)Department of Cardiovascular Medicine, The University of Tokushima
ENDOCRINE JOURNAL 57 (suppl.2-2) S561-S561, 2010.

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P9-6-6 Menopausal symptoms and the metabolic syndrome in women with type 2 DM

Anthonia O.Ogbera
Department of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S561-S561, 2010.

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P9-6-7 Association between Insulin-like growth factor-I and the incidence of metabolic syndrome:Results from the study of health in Pomerania

Nele Friedrich(1), Matthias Nauck(1), Henry Voelzke(2), Georg Brabant(3), Henri Wallaschofski(1)
(1)Institute of Clinical Chemistry and Laboratory Medicine, University Greifswald, (2)Institute for Community Medicine, University Greifswald, (3)Department of Endocrinology, Christie Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S561-S562, 2010.

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P9-6-8 Association study between the insulin-like growth factor-1 gene and cerebral infarction in Japanese subjects

Noriko Aoi(1), Tomohiro Nakayama(2), Masayoshi Soma(3), Kotoko Kosuge(3), Mikano Sato(4), Satoshi Asai(1), Koichi Matsumoto(4)
(1)Division of Genomic Epidemiology and Clinical Trials, Department of Advanced Medical Science, Nihon University School of Medicine, (2)Division of Laboratory Medicine, Department of Pathology and Microbiology, Nihon University School of Medicine, (3)Division of General Medicine, Department of Medicine, Nihon University School of Medicine, (4)Division of Nephrology, Hypertension and Endocrinology, Department of Medicine, Nihon University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S562-S562, 2010.

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P9-7-1 Transcriptional regulation for a progressive renal disease by a gene silencer pyrrole-imidazole polyamide targeting TGF-β1 promoter

Noboru Fukuda(1), (2), Hiroyuki Matsuda(1), (2), Takahiro Ueno(1), Hiroki Nagase(2), Koichi Matsumoto(1)
(1)Division of Nephrology, Hypertension and Endocrinology, Department of Medicine, Nihon University School of Medicine, (2)Advanced Research Institute of Science and Humanities, Nihon University
ENDOCRINE JOURNAL 57 (suppl.2-2) S562-S562, 2010.

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P9-7-2 Complement 3 is involved in the cardiovascular remodeling in hypertension

Noboru Fukuda, Kazuya Ikeda, Han Ying, Takahiro Ueno, Akiko Tsunemi, Koichi Matsumoto
Division of Nephrology, Hypertension and Endocrinology, Department of Medicine, Nihon University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S562-S562, 2010.

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P9-7-3 Pyridoxamine ameliorates glomerular injury in rat chronic glomerulonephritis

Takashi Nakamichi(1), Takefumi Mori(1), Yoshimi Yoneki(1), Yusuke Ohsaki(1), Guo Qi(1), Toshinobu Sato(2), Hiroshi Sato(1), Sadayoshi Ito(1)
(1)Divison of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University, (2)Division of Blood Purification, Tohoku University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S562-S563, 2010.

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P9-7-4 Effectiveness of calorie restriction on ameliorating diabetic nephropathy possibly through its anti-inflammatory action

Daisuke Koya(1), Shinji Kume(2), Eiko Kobiri(1)
(1)Endocrinology & Metabolism, Kanazawa Medical University, (2)Department of Medicine, Shiga University of Medical Science
ENDOCRINE JOURNAL 57 (suppl.2-2) S563-S563, 2010.

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P9-7-5 The role of fibroblast grow factor 23 in vascular calcification

Bohumil Majtan(1), (2), Tatsuo Shimosawa(2), Hong Wang(2), Shengyu Mu(2), Sayoko Ogura(2), Yuzaburo Uetake(2), Fumiko Mori(2), Robert Holaj(1), Toshiro Fujita(2)
(1)3rd Internal Department General Teaching Hospital, and 1st Faculty of Medicine, Charles University in Prague, (2)Department of Nephrology and Endocrinology, University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S563-S563, 2010.

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P9-7-6 Mutations in renal drug efflux transporter hOATv1 cause hyperuricemia

Promsuk Jutabha(1), Naohiko Anzai(1), Kenichiro Kitamura(2), Atsuo Taniguchi(3), Shuji Kaneko(4), Hideomi Yamada(5), Hidetaka Shimada(6), Kohei Uchimura(2), Manabu Hayata(2), Jun Morinaga(2), Wako Urano(3), George Seki(5), Shunya Uchida(7), Hitoshi Endou(1), (8), Hiroyuki Sakurai(1)
(1)Department of Pharmacology and Toxicology, Kyorin University School of Medicine, (2)Department of Nephrology, Kumamoto University Graduate School of Medical and Pharmaceutical Sciences, (3)Institute of Rheumatology, Tokyo Women's Medical University, (4)Department of Molecular Pharmacology, Kyoto University Graduate School of Pharmaceutical Sciences, (5)Department of Internal Medicine, Faculty of Medicine, The University of Tokyo, (6)Shimada Hospital, (7)Division of Nephrology, Department of Internal Medicine, Teikyo University School of Medicine, (8)J-Pharma Co.Ltd
ENDOCRINE JOURNAL 57 (suppl.2-2) S563-S563, 2010.

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P9-7-7 Serum uric acid and prevalence of metabolic syndrome:Adult Health Study in Hiroshima

Yoshimi Tatsukawa(1), Naomi Masunari(1), Michiko Yamada(1), Masayuki Hakoda(2), Kiminori Yamane(3), Saeko Fujiwara(1)
(1)Department of Clinical Studies, Radiation Effects Research Foundation, (2)Faculty of Human Ecology, Yasuda Women's University, (3)Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University
ENDOCRINE JOURNAL 57 (suppl.2-2) S563-S564, 2010.

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P9-7-8 A case of exercise-induced acute renal failure associated with idiopathic renal hypouricemia

Kenichi Koga(1), Masato Kasahara(1), Keisuke Osaki(1), Kiyoshi Mori(1), Hideki Yokoi(1), Yoshihisa Ogawa(1), Takashige Kuwabara(1), Hirotaka Imamaki(1), Tomoko Kawanishi(1), Akira Ishii(1), Akira Sugawara(2), Masashi Mukoyama(1), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Division of Nephrology, National Hospital Organization Kyoto Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S564-S564, 2010.

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P9-8-1 Development of mice with a conditional allele for HSD11B1:Understanding the contribution of hepatic 11β-hydroxysteorid dehydrogenase type 1 to metabolic disease.

Gareth G.Lavery, Elizabeth H.Rabbitt, Khalid Saqib, Mark Sherlock, Elizabeth A.Walker, Paul M.Stewart
School of Clinical and Experimental Medicine, University of Birmingham
ENDOCRINE JOURNAL 57 (suppl.2-2) S564-S564, 2010.

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P9-8-2 Urinary angiotensinogen and sodium sensitivity of blood pressure in patients with IgA nephropathy and Meniere's disease

Akira Nishiyama(1), Yoshio Konishi(2), Hideyasu Kiyomoto(3), Takenori Miyashita(4), Nobomu Mori(4), Hirofumi Hitomi(1), Hiroyuki Kobori(5), Masahito Imanishi(2)
(1)Department of Pharmacology, Kagawa University Medical School, (2)Division of Nephrology and Hypertension, Osaka City General Hospital, (3)Department of Nephrology, Kagawa University Medical School, (4)Department of Otolaryngology, Kagawa University Medical School, (5)Department of Physiology, and Hypertension and Renal Center of Excellence, Tulane University Health Sciences Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S564-S564, 2010.

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P9-8-3 A haplotype-based case-control study of extracellular superoxide dismutase gene with cerebral infarction

Tomohiro Nakayama(1), Takahiro Naganuma(2), Naoyuki Sato(1), Zhenyan Fu(1), Noriko Aoi(3), Masayoshi Soma(4), Nobutaka Doba(5), Shigeaki Hinohara(5), Ron Usami(2)
(1)Division of Laboratory Medicine, Department of Pathology and Microbiology, Nihon University School of Medicine, (2)Department of Biological Applied Chemistry, Toyo University Graduate School of Engineering, (3)Division of Genomic Epidemiology and Clinical Trials, Department of Advanced Medical Science, Nihon University School of Medicine, (4)Division of General Medicine, Department of Medicine, Nihon University School of Medicine, (5)The Life Planning Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S564-S565, 2010.

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P9-8-4 CT dinucleotide repeat polymorphism in the promoter region of Guanylyl Cyclase(GC)-A gene is associated with essential hypertension in the Japanese

Satoru Usami(1), Ichiro Kishimoto(2), Koichiro Kuwahara(1), Yasuaki Nakagawa(1), Shinji Yasuno(1), Hideyuki Kinoshita(1), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)National Cardiovascular Center, Research Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S565-S565, 2010.

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P9-8-5 Genetic variant of the renin angiotensin system and diabetes influences blood pressure response to angiotensin receptor blocker

Tadashi Konoshita(1), Norihiro Kato(2), Sebastien Fuchs(3), Shinichi Mizuno(1), Chikako Aoyama(1), Makoto Motomura(1), Tomoko Kimura(1), Miki Fujii(1), Yasukazu Makino(1), Shigeyuki Wakahara(1), Kenichiro Arakawa(1), Isao Inoki(1), Florence Pinet(4), Isamu Miyamori(1)
(1)Third Department of Internal Medicine, Fukui University School of Medicine, (2)Department of Gene Diagnostics and Therapeutics, Research Institute, International Medical Center of Japan, (3)Department of Biomedical Sciences, Cedars-Sinai Medical Center, (4)INSERM UMR744, Institut Pasteur de Lille
ENDOCRINE JOURNAL 57 (suppl.2-2) S565-S565, 2010.

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P9-8-6 Serum lipid profile of hypertensive & normotensive diabetes mellitus patients:A comparative study

Muhammad Nauman A.Jadoon, Rehan Yaqoob, Muhammad A.Shehzad
Diabetes Research Centre Nishtar Medical College, Multan affiliated with the University of Health Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S565-S565, 2010.

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P9-8-7 Prevalence of hypertension among patients with type 2 diabetes

Muhammad Nauman A.Jadoon, Muhammad A.Shehzad, Rehan Yaqoob
Diabetes Research Centre Nishtar Medical College, Multan affiliated with the University of Health Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S565-S566, 2010.

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P9-8-8 Seasonal variability of home blood pressure along with noradrenalin in hemodialyzed patients evaluated by telemedicine system using cellular phone

Munekazu Ryuzaki(1), (2), Emi Kobayashi(1), Chie Takimoto(1), Takashi Shishido(1), Michiko Handa(1), Hidetomo Nakamoto(2), Yuka Suzuki(3), Takeo Nagare(3), Masayoshi Sone(4), Hiroshi Itoh(5)
(1)Department of Internal Medicine, Kawasaki Municipal Ida Hospital, (2)Department of General Medicine, Saitama Medical University, (3)Clinography Co. Ltd, (4)Sone Clinic, (5)Department of Internal Medicine, Keio University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S566-S566, 2010.

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P9-9-1 Blockade of T-Type Ca2+ channel corrects cardiac autonomic nervous system imbalance and prevents sudden death in mice with heart failure

Yoshihiro Kuwabara(1), Koishiro Kuwahara(1), Makoto Takano(2), Yuji Arai(3), Hideyuki Kinoshita(1), Yuko Yamada(1), Takeya Minami(1), Masataka Fujiwara(1), Satoru Usami(1), Shinji Yasuno(1), Yasuaki Nakagawa(1), Masaki Harada(1), Masao Murakami(1), Kenji Ueshima(4), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Biophysics, Jichi Medical School, (3)Department of Bioscience, National Cardiovascular Center Research Institute, (4)EBM Research Center, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S566-S566, 2010.

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P9-9-2 N-type Ca2+ channel blockade prevents sudden death in mice with heart failure

Yuko Yamada, Koichiro Kuwahara, Hideyuki Kinoshita, Yoshihiro Kuwabara, Yasuaki Nakagawa, Masaki Harada, Shinji Yasuno, Takeya Minami, Satoshi Usami, Masataka Fujiwara, Masao Murakami, Kenji Ueshima, Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto University Gradual School of Medicine, Kyoto, Japan
ENDOCRINE JOURNAL 57 (suppl.2-2) S566-S566, 2010.

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P9-9-3 Functional inhibition of p300 affects the mitochondrial function and cell survival in the post-natal heart in mice

Yasuaki Nakagawa(1), Koichiro Kuwahara(1), Genzo Takemura(2), Masaharu Akao(3), Yuji Arai(4), Masaki Harada(1), Satoru Usami(1), Shinji Yasuno(5), Hideyuki Kinoshita(1), Masataka Fujiwara(1), Yoshihiro Kuwabara(1), Takeya Minami(1), Chinatsu Yamada(1), Kenji Ueshima(5), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Cardiology and Respirology, Regeneration and Advanced Medical Sciences, Graduate School of Medicine, Gifu University, (3)Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, (4)Department of Bioscience, National Cardiovascular Center Research Institute, (5)EBM Research Center, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S566-S567, 2010.

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P9-9-4 Ras independent manner:COX-2 induction by ACE-ACE inhibitor signaling prevents development of diastolic dysfunction

Takaaki Senbonmatsu, Yoshimi Aizaki, Shin-ichiro Iida, Ayumu Yoshikawa, Toshihiro Muramatu, Shigeyuki Nishimura
Department of Pharmacology, Saitama Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S567-S567, 2010.

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P9-9-5 Compositional analysis of A, C, G, T IN KCNQ1, KCNH2, SCN5A genes involved in LQTS syndrome

R.Sridhar Gumpeny(1), Venkataswamy Galla(2), Susmita Valli Gogula(2), Vamsidhar Enireddy(2), Appa Rao Allam(3)
(1)Endocrine and Diabetes Centre, (2)GITAM University, (3)JNTU
ENDOCRINE JOURNAL 57 (suppl.2-2) S567-S567, 2010.

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P9-9-6 Prediction of active sites in butyrylcholinesterase using THEMATICS program

R.Sridhar Gumpeny(1), Suryanarayana Dasika(2), Appa Rao Allam(3)
(1)Endocrine and Diabetes Centre, (2)S.R.K.R.Engineering College Bhimavaram, (3)JNTU
ENDOCRINE JOURNAL 57 (suppl.2-2) S567-S567, 2010.

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P9-9-7 Increased serum triglyceride is associated with left ventricular diastolic dysfunction

Ken-ichi Aihara, Sumiko Yoshida, Kiyoe Kurahashi, Mizuho Kinouchi, Itsuro Endo, Yuichi Fujinaka, Toshio Matsumoto
Department of Medicine and Bioregulatory Sciences, The University of Tokushima, Graduate School of Health Biosciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S567-S568, 2010.

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P9-9-8 Antihypertensive therapy induced transient coma in patient with severe stenosis of the common carotid arteries

Kunmitsu Iwai, Kumiko Ynnagida, Mikiko Atsumi, Hirosi Yano, Koji Nomura, Junta Sakai, Hirosi Murai, Takeshi Nakahashi, Hirosi Tsuchiya, Sigeto Morimoto
Department of Geriatric Medicine, Kanazawa Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S568-S568, 2010.

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P9-10-1 Rosuvastatin exerts an LDL cholesterol reduction-independent protective effect against carotid atherosclerosis

Sumiko Yoshida(1), Ken-ichi Aihara(1), Yuka Ueda(1), Kiyoe Kurahashi(1), Mizuho Kinouchi(1), Itsuro Endo(1), Yuichi Fujinaka(1), Takashi Iwase(2), Masashi Akaike(2), Masataka Sata(2), Toshio Matsumoto(1)
(1)Department of Medicine and Bioregulaotry Sciences, The University of Tokushima, (2)Department of Cardiovascular Medicine, The University of Tokushima
ENDOCRINE JOURNAL 57 (suppl.2-2) S568-S568, 2010.

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P9-10-2 Carotid intima-media thickness and high-sensitivity C-reactive protein in a population of middle-aged Koreans:Relation to metabolic syndrome

Mina Suh(1), Myoung Ha Lee(2), Dong Phil Choi(2), Song Vogue Ahn(1), Hyeon Chang Kim(1), Il Suh(1)
(1)Department of Preventive Medicine, Yonsei University College of Medicine, (2)Department of Public Health, Graduate School of Yonsei University
ENDOCRINE JOURNAL 57 (suppl.2-2) S568-S568, 2010.

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P9-10-3 Metabolic syndrome by different definitions and increased carotid intima-media thickness:KoGES-Kangwha

Kyoung hwa Ha
The Department of Public Health, Graduate School of Yonsei University
ENDOCRINE JOURNAL 57 (suppl.2-2) S568-S569, 2010.

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P9-10-4 Oxidized LDL and other vascular risk factors

Gustavo Rocha, Isabel M.Palma, Fatima O.Borges, Paula M.Costa, Fernanda Bravo, Jose C.Oliveira, Helena Ramos
Endocrinology Department, Hospital Santo Antonio
ENDOCRINE JOURNAL 57 (suppl.2-2) S569-S569, 2010.

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P9-10-5 Significance of strict blood pressure and lipid control on kidney protection in very early stage of chronic kidney disease(CKD)

Akira Sugawara, Chinatsu Okamoto, Yuko Kikuchi, Koichi Seta, Kensei Yahata, Keiichi Kaneko, Yukiko Kato, Shoko Ohno, Mitsuteru Koizumi
Kidney Center, Kyoto Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S569-S569, 2010.

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P9-10-6 Comparison of the effect of cilostazol with aspirin on circulating endothelial progenitor cells and small-dense LDL cholesterol in diabetic patients with cerebral ischemia:Randomized controlled trial

Hidenori Koyama, Hiroki Ueno, Yohei Mima, Shinya Fukumoto, Shinji Tanaka, Takuhito Shoji, Masanori Emoto, Tetsuo Shoji, Masaaki Inaba, Yoshiki Nishizawa
Department of Metabolism, Endocrinology and Molecular Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S569-S569, 2010.

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P9-10-7 Transcriptional factor prolactin regulatory element-binding protein-mediated gene transcription of ABCA1 via3', 5'-cyclic adenosine-5'-monophosphate in vascular smooth muscle cells

Takuo Yoshimoto, Koji Murao, Hitomi Imachi, Yukiko Nishiuchi, Tomie Muraoka, Fumi Kikuchi, Toshihiko Ishida
Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Kagawa University
ENDOCRINE JOURNAL 57 (suppl.2-2) S569-S570, 2010.

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P9-10-8 Development of PI polyamide targeting human ABCA1 gene

Akiko Tsunemi(1), Takahiro Ueno(1), Noboru Fukuda(2), Takayoshi Watanabe(3), Kazunobu Tahira(1), Shiro Matsumoto(1), Chinami Nagura(1), Taro Matsumoto(1), Masayoshi Soma(4), Koichi Matsumoto(1), Yoshiaki Matsumoto(5), Hiroki Nagase(3), Hiroshi Sugiyama(6)
(1)Division of Nephrology, Hypertension and Endocrinology, Department of Medicine, Nihon University School of Medicine, (2)Advanced Research Institute for the Sciences and Humanities, Nihon University Graduate School, (3)Division of Cancer Genetics, Department of Advanced Medical Science, Nihon University School of Medicine, (4)Division of General Medicine, Department of Medicine, Nihon University School of Medicine, (5)Department of Clinical Pharmacokinetics, Collage of Phamacy, Nihon University, (6)Department of Chemistry, Kyoto Graduate School of Science
ENDOCRINE JOURNAL 57 (suppl.2-2) S570-S570, 2010.

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P9-11-1 Combination of hyperglycemia and hyperlipidemia synergistically aggravates albuminuria, tubular lipid accumulation and macrophage infiltration, in parallel with inflammation and extracellular matrix expression

Takashige Kuwabara(1), Kiyoshi Mori(1), Masashi Mukoyama(1), Masato Kasahara(1), Hideki Yokoi(1), Yoshihisa Ogawa(1), Hirotaka Imamaki(1), Tomoko Kawanishi(1), Akira Ishii(1), Kenichi Koga(1), Akira Sugawara(2), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Nephrology, Kyoto Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S570-S570, 2010.

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P9-11-2 Neutrophils are the predominant source of circulating Ngal in normal conditions and during infection, but not in acute kidney injury

Kiyoshi Mori(1), Junya Kanda(2), Masashi Mukoyama(1), Hiroshi Kawabata(2), Masato Kasahara(1), Hideki Yokoi(1), Chisaki Mizumoto(2), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University
ENDOCRINE JOURNAL 57 (suppl.2-2) S570-S570, 2010.

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P9-11-3 Overexpression of connective tissue growth factor in podocytes worsens diabetic nephropathy by reducing MMP-2 activity

Hideki Yokoi(1), (2), Masashi Mukoyama(1), Masato Kasahara(1), Kiyoshi Mori(1), Yoshihisa Ogawa(1), Takashige Kuwabara(1), Hirotaka Imamaki(1), Tomoko Kawanishi(1), Akira Ishii(1), Kenichi Koga(1), Akira Sugawara(2), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Division of Nephrology, Kyoto Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S570-S571, 2010.

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P9-11-4 Role of 12-hydroxyeicosatetraenoicacid(12-HETE)in diabetic cardiomyopathy

Masaya Sakamoto(1), Takahiro Suzuki(1), Yuri Takada(1), Keiichi Ikeda(2), Katsuyoshi Tojo(1), Naoko Tajima(1)
(1)Department of Internal Medicine, Division of Diabetes and Endocrinology, Jikei University School of Medicine, (2)Department of Pharmacology, The Jikei University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S571-S571, 2010.

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P9-11-5 Dorsal pedal artery intima-media thickness could predict three-vessel or left main coronary artery disease in type 2 diabetics

Dandan Zhang(1), Yiming Mu(2)
(1)Department of cardiology, General hospital of China Air force, (2)Department of Endocrinology and mMtabolism, General Hospital of Chinese PLA
ENDOCRINE JOURNAL 57 (suppl.2-2) S571-S571, 2010.

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P9-11-6 Candesartan improves fatty liver in Koletsky obese rats lacking leptin receptor signaling:an intra-hepatic mechanism that involves inhibition of fatty acid biosynthesis

Yuhao Li, Xianglu Rong, Ken Ebihara, Mingming Zhao, Toru Kusakabe, Tsutomu Tomita, Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S571-S571, 2010.

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P9-11-7 The atherogenic index in the fatty liver

Gungor Akcay(1), Mufide Nuran Akcay(2)
(1)Division of Endocrinology, Department of Internal Medicine, School of Medicine, University of Ataturk, (2)Department of Surgery, School of Medicine, University of Ataturk
ENDOCRINE JOURNAL 57 (suppl.2-2) S571-S571, 2010.

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P9-11-8 Effect of treatment with insulin sensitizer on arterial properties, metabolic parameters and liver function in patients with nonalcoholic fatty liver disease:A randomized, placebo-controlled trial

Marina Shargorodsky, Safer Elena, Reuven Zimlichman
wolfson medical center and Sackler School of Medicine, Tel Aviv University
ENDOCRINE JOURNAL 57 (suppl.2-2) S572-S572, 2010.

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P9-12-1 Induction of gene expression in response to globular adiponectin in vascular endothelial cells

Atsuko Tomizawa, Yoshiyuki Hattori, Kikuo Kasai
Dokkyo University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S572-S572, 2010.

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P9-12-2 Statins improve vascular endothelial function in hypercholesterolemic patients with type 2 diabetes mellitus

Toshie Okayasu, Atsuko Tomizawa, Chie Aoki, Ayuko Nakano, Noriko Hirama, Teruo Jojima, Yoshiaki Kawagoe, Hiroyuki Kase, Yoshiyuki Hattori, Kikuo Kasai
Dokkyo University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S572-S572, 2010.

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P9-12-3 Prostacyclin analogs rapidly stimulates endothelial nitric oxide synthase phosphorylation through cAMP/PKA pathway in vascular endothelial cells

Masataka Kudo(1), Akira Sugawara(2), Akiko Saito(4), Fumitoshi Satoh(1), Akira Uruno(3), Sadayoshi Ito(1)
(1)Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, (2)Department of Advanced Biological Sciences for Regeneration, Tohoku University Graduate School of Medicine, (3)Department of Biochemistry, Tohoku University Graduate School of Medicin, (4)Department of Pediatrics, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S572-S573, 2010.

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P9-12-4 Enhanced expression of monocyte chemoattractant protein(MCP)-1 in vascular smooth muscle cells with overexpressed receptor for advanced glycation end products(RAGE)

Eri Hayakawa, Takanobu Yoshimoto, Naoko Sekizawa, Kyoichiro Tsuchiya, Toru Sugiyama, Yukio Hirata
Department of Clinical and Molecular Endcrinology, Tokyo Medical and Dental University Graduate School
ENDOCRINE JOURNAL 57 (suppl.2-2) S573-S573, 2010.

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P9-12-5 High sodium augments angiotensin II-induced proliferation of rat vascular smooth muscle cell through an ERK1/2-dependent pathway

Hirofumi Hitomi(1), Gang Liu(1), Naohisa Hosomi(2), Hideyasu Kiyomoto(2), Daisuke Nakano(1), Shoji Kimura(1), Takahiro Iwamoto(3), Masakazu Kohno(2), Akira Nishiyama(1)
(1)Department of Pharmacology, Kagawa University, (2)Department of Cardiorenal and Cerebrovascular Medicine, Kagawa University, (3)Department of Pharmacology, Fukuoka University
ENDOCRINE JOURNAL 57 (suppl.2-2) S573-S573, 2010.

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P9-12-6 Purification and Identification of magnesium lithospermate B(LAB)-binding protein, nonmuscle myosin heavy chain(NMMHC)from VSMC

J.M.Kim(1), (2), M.K.Jung(3), Hyun Chul Lee(1), (2), Eun Jing Lee(2)
(1)Brain Korea 21 Project for Medical Science, University of Yonsei, (2)Department of Internal Medicine, Yonsei University College of Medicine, (3)Department of Chemistry, Yonsei University
ENDOCRINE JOURNAL 57 (suppl.2-2) S573-S573, 2010.

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P9-12-7 Magnesium lithospermate B and its related derivatives inhibit vascular smooth muscle cell proliferation through reducing intracellular reactive oxygen species and activating Sirt1 pathway

Yoonhee Cho(1), Eun Jig Lee(1), (2)
(1)Department of Severance Hospital Integrative Research Institute for Cerebral & Cardiovascular Disease, Yonsei University College of Medicine, (2)Division of Endocrinology, Yonsei University, College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S573-S574, 2010.

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P9-12-8 Adrenomedullin treatment reduces intestinal inflammation in mice administered dextran sulphate sodium

Kazuo Kitamura(1), Shinya Ashizuka(1), Kyoko Inagaki-Ohara(2), (3), Kenji Kuwasako(4), Johji Kato(4), Haruhiko Inatsu(1)
(1)Department of Internal Medicine, Circulatory and Body Fluid Regulation, Faculty of Medicine, University of Miyazaki, (2)Molecular Microbiology Group, Center of Molecular Biosciences(COMB), Tropical Biosphere Research Center, University of the Ryukyus, (3)Parasitic Disease Unit, Department of Infectious Disease, Faculty of Medicine, University of Miyazaki, (4)Frontier Science Research Center, University of Miyazaki
ENDOCRINE JOURNAL 57 (suppl.2-2) S574-S574, 2010.

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P9-13-1 Association of steroidogenic genes polymorphisms with essential hypertension, aldosterone level and left ventricular structure

Masanori Shimodaira(1), (2), Tomohiro Nakayama(1), (3), (4), Naoyuki Sato(3), Noriko Aoi(3), (4), Mikano Sato(3), (4), Yoichi Izumi(4), Masayoshi Soma(4), Koichi Matsumoto(4)
(1)Division of Laboratory Medicine, Department of Pathology of Mixbiology, Nihon University School of Medicine, (2)Division of Hematology, Endocrinology and Metabolism, Tokyo Metropolitan Hiroo Hospital, (3)Division of Molecular Diagnostics, Department of Advanced Medical Science, Nihon University School of Medicine, (4)Divisions of Nephrology and Endocrinology and General Medicine, Department of Medicine, Nihon University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S574-S574, 2010.

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P9-13-2 Endogenous androgen exaggerates hypertension in spontaneously hypertensive rats through CYP4A2 and 20-hydroxyeicosatetraenoic acid

Osamu Ito(1), Tsuneo Ishizuka(2), Yoshiko Yoneki(2), Takefumi Mori(2), Yoshikazu Muroya(1), Daisuke Ito(1), Ken Omata(3), Sadayoshi Ito(2), Masahiro Kohzuki(1)
(1)Department of Internal Medicine and Rehabilitation Science, Tohoku University Graduate School of Medicine, (2)Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, (3)Health Administration Center, Miyagi University of Education
ENDOCRINE JOURNAL 57 (suppl.2-2) S574-S574, 2010.

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P9-13-3 Characterising the Aromatase and apolipoprotein E deficient mouse for studying the metabolic syndrome

Nicola J.A.Scott(1), Leigh J.Ellmers(1), Sara Raudsepp(1), Evan R.Simpson(2), A.Mark Richards(1), Vicky A.Cameron(1)
(1)Department of Medicine, University of Otago-Christchurch, (2)Prince Henrys Institute for Medical Research
ENDOCRINE JOURNAL 57 (suppl.2-2) S574-S575, 2010.

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P9-13-4 Apolipoprotein E isoforms are associated with age of onset of coronary disease but not subsequent mortality in a coronary disease cohort

Nicola JA Scott(1), Katrina L.Ellis(1), Leigh J.Ellmers(1), Chris M.Frampton(1), Lorraine Skelton(1), Rob N.Doughty(2), Chris J.Ellis(2), Gillian A.Whalley(2), Timothy G.Yandle(1), A Mark Richards(1), Vicky A.Cameron(1)
(1)Department of Medicine, University of Otago-Christchurch, (2)Department of Medicine, Faculty of Medicine and Health Sciences, University of Auckland
ENDOCRINE JOURNAL 57 (suppl.2-2) S575-S575, 2010.

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P9-13-5 Pueraria mirifica phytoestroges improve dyslipidemia in postmenopausal women probably by activating estrogen receptor subtypes

Akiko Katano(1), Tetsurou Satoh(1), Shinichi Okamura(2), Yosie Sawada(2), Koshi Hashimoto(1), Masanobu Yamada(1), Tsutomu Ishikawa(3), Tetsuo Sakamaki(2), Masatomo Mori(1)
(1)Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, (2)Department of Medical Informatics and Decision Sciences, School of Medicine, Gunma University, (3)Graduate School of Pharmaceutical Sciences, Chiba University
ENDOCRINE JOURNAL 57 (suppl.2-2) S575-S575, 2010.

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P9-13-6 The association of salivary cortisol with cardiovascular risks and efficacy of weight reduction therapy in obese patients

Akihiro Himeno(1), (2), Noriko Satoh(1), Takeshi Usui(1), Hiromichi Wada(1), Kazunori Yamada(2), Nobuko Yamada(3), Koji Hasegawa(1), Akira Shimatsu(1), Goro Katsuura(3), Kazuwa Nakao(3)
(1)Clinical Research Institute, Kyoto Medical Center, (2)Diabetes Center, Kyoto Medical Center, (3)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S575-S575, 2010.

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P9-13-7 Production of proopiomelanocortin by cardiomyocytes

Keiichi Ikeda(1), Katsuyoshi Tojo(2), Masaya Sakamoto(2), Yuko Takada(2), Yuri Inada(2), Yutaka Oki(3), William C Claycomb(4)
(1)Department of Pharmacology, The Jikei University School of Medicine, (2)Division of Diabetes and Endocrinology, Department of Internal Medicine, The Jikei University School of Medicine, (3)Second Division, Department of Medicine, Hamamatsu University School of Medicine, (4)Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S575-S576, 2010.

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P9-13-8 Nutritional regulation and physiological role of ELOVL family member 5(Elovl5)

Takashi Matsuzaka, Saori Koyasu, Yoshimi Nakagawa, Tomotaka Yokoo, Nobuhiro Yamada, Hitoshi Shimano
Department of Endocrinology and Metabolism, University of Tsukuba
ENDOCRINE JOURNAL 57 (suppl.2-2) S576-S576, 2010.

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P9-14-1 Role of aldosterone in the initiation of renal insulin resistance

Hitoshi Minakuchi, Shu Wakino, Keiko Fujimura, Kazuhiro Hasegawa, Yoshikazu Hara, Kyoko Yoshioka, Satoru Tatematsu, Naoki Washida, Hirobumi Tokuyama, Koichi Hayashi, Hiroshi Itoh
Department of Internal Medicine, University of Keio
ENDOCRINE JOURNAL 57 (suppl.2-2) S576-S576, 2010.

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P9-14-2 Regulation of adrenal aldosterone production by serine protease prostasin

Kenichiro Kitamura, Taku Miyoshi, Yutaka Kakizoe, Kohei Uchimura, Manabu Hayata, Jun Morinaga, Naoki Shiraishi, Masataka Adachi, Kimio Tomita
Department of Nephrology, Kumamoto University Graduate School of Medical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S576-S576, 2010.

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P9-14-3 Role of prostasin in the nitric oxide-mediated natriuresis in the kidney

Taku Miyoshi, Kenichiro Kitamura, Yutaka Kakizoe, Kohei Uchimura, Manabu Hayata, Jun Morinaga, Naoki Shiraishi, Masataka Adachi, Kimio Tomita
Department of Nephrology, Kumamoto University Graduate School of Medical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S576-S577, 2010.

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P9-14-4 Camostat mesilate attenuates hypertension and kidney injury in Dahl salt-sensitive rats

Yutaka Kakizoe, Kenichiro Kitamura, Taku Miyoshi, Kohei Uchimura, Manabu Hayata, Jun Morinaga, Naoki Shiraishi, Masataka Adachi, Kimio Tomita
Department of Nephrology, Kumamoto University Graduate School of Medical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S577-S577, 2010.

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P9-14-5 Blockade of T-type calcium channel with R(-)efonidipine ameliorates the renal ischemia induced by angiotensin II in Spregue-Dawley rats

Chunyan Hu(1), Takefumi Mori(1), (2), Qi Guo(1), Yoshimi Yoneki(1), Takashi Nakamichi(1), Sadayoshi Ito(1)
(1)Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, (2)Health Administration Center, Tohoku University
ENDOCRINE JOURNAL 57 (suppl.2-2) S577-S577, 2010.

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P9-14-6 High fat loading accelerates salt-induced development of hypertension and renal damage in dahl salt-sensitive rats

Katsuyuki Ando, Megumi Fujita, Ai Nagae, Hiroo Kawarazaki, Toshiro Fujita
Department of Nephrology and Endocrinology, University of Tokyo Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S577-S577, 2010.

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P9-14-7 Role of the CCN family(CCN1, CCN2)for glomerular remodeling and podocyte injury in chronic kidney disease

Masashi Mukoyama(1), Hideki Yokoi(1), Kiyoshi Mori(1), Masato Kasahara(1), Kazutomo Sawai(2), Kenji Kangawa(2), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Biochemistry, National Cardiovascular Center Research Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S577-S578, 2010.

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P9-14-8 A case of survivor found with severe hypothermia 25-days after lost in a mountain

Takeya Minami(1), (2), Shinichi Sato(2), Kouichi Ariyoshi(2), Kouichiro Kuwahara(1), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Emergency Department of Kobe city medical center general hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S578-S578, 2010.

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P10-1-1 AH receptor activation by ETK tyrosine kinase in ER alpha-negative MCF10AT1 breast cancer cells

Yasuko Fujisawa(1), Fumio Matsumura(2), Wen Li(2), Patric Wong(2), Christoph Vogel(2), Hsing-Jien Kung(3), Yuichi Nakagawa(1), Takehiko Ohzeki(1)
(1)Department of Pediatrics, Hamamatsu University School of Medicine, (2)Department of Environmental Toxicology, University of California Davis, (3)Cancer Research Center, UCD Medical Center, University of California Davis
ENDOCRINE JOURNAL 57 (suppl.2-2) S578-S578, 2010.

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P10-1-2 Immunolocalization of NUCB2 in human breast carcinoma

Shiho Suzuki(1), Yoshiaki Onodera(2), Yasuhiro Miki(2), Jun-ichi Akahira(2), Hironobu Sasano(2), Takashi Suzuki(1)
(1)Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine, (2)Department of Anatomic Pathology, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S578-S578, 2010.

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P10-1-3 Intratumoral androgen levels in breast carcinoma with aromatase inhibitor exemestane:17β-hydroxysteroid dehydrogenase type 2 as a marker for increased androgen actions

Kiyoshi Takagi(1), Shoji Nagasaki(2), (4), Yoshiaki Onodera(2), Yasuhiro Miki(2), Jun-ichi Akahira(2), Katsuhiko Ono(2), Hisashi Hirakawa(3), Hironobu Sasano(2), Takashi Suzuki(1)
(1)Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine, (2)Department of Anatomic Pathology, Tohoku University Graduate School of Medicine, (3)Department of Surgery, Tohoku Kosai Hospital, (4)Kawasaki Research Center, ASKA Pharmaceutical Co., Ltd
ENDOCRINE JOURNAL 57 (suppl.2-2) S578-S579, 2010.

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P10-1-4 Identification of estradiol-estrogen receptor-regulated miRNAs in breast cancer cells

Mariko Masuda, Shuko Hata, Yasuhiro Miki, Hironobu Sasano
Department of Pathology, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S579-S579, 2010.

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P10-1-5 Evaluation of tumor microenvironment-regulated estrogen signals in individual breast cancers and their adjacent stromal fibroblasts

Yuri Yamaguchi(1), Hanako Oba(2), Kenichi Inoue(3), Yuko Seino(1), (5), Toshio Tabei(3), Hiroyuki Takei(4), Masafumi Kurosumi(2), Shin-ichi Hayashi(5)
(1)Research Institute for Clinical Oncology, Saitama Cancer Center, (2)Department of Pathology, Saitama Cancer Center, (3)Division of Breast Oncology, Saitama Cancer Center, (4)Division of Breast Surgery, Saitama Cancer Center, (5)Department of Molecular Functional Dynamics, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S579-S579, 2010.

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P10-1-6 Effects of retinoic acid and vitamin D selected analogs on nuclear receptors expression in MNU-induced mammary tumors in female Sprague-Dawley rats

Dana Macejova(1), Slavomira Ondkova(1), Jan Liska(1), (2), Lucia Jakubikova(1), (3), Julius Brtko(1)
(1)Institute of Experimental Endocrinology SAS, (2)Institute of Histology and Embryology, Comenius University, (3)BIONT Corp
ENDOCRINE JOURNAL 57 (suppl.2-2) S579-S579, 2010.

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P10-1-7 Tissue concentration of sex steroid hormones and its correlations with clinicopathological parameters in human epithelial ovarian cancer

Jun-ichi Akahira(1), Fumihiko Suzuki(2), Takashi Suzuki(3), Yasuhiro Miki(1), Shuji Nagasaki(4), Seijiro Honma(5), Kiyoshi Ito(2), Nobuo Yaegashi(2), Hironobu Sasano(1)
(1)Department of Pathology, Tohoku University Graduate School of Medicine, (2)Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, (3)Department of Pathology and histotechnology, Tohoku University Graduate School of Medicine, (4)Kawasaki Research Center, ASKA Pharmaceutical Co., Ltd, (5)ASKA Pharmamedical Co.Ltd
ENDOCRINE JOURNAL 57 (suppl.2-2) S579-S579, 2010.

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P10-1-8 A cell cycle regulator, transforming acidic coiled-coil protein 2(TACC2), is an androgen-regulated gene that promotes prostate cancer progression

Kenichi Takayama(1), (2), (3), Takashi Suzuki(4), Kuniko Horie-Inoue(3), Kazuhiro Ikeda(3), Tomohiko Urano(1), (2), (3), Yasuyoshi Ouchi(1), Satoshi Inoue(1), (2), (3)
(1)Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, (2)Department of Anti-aging Medicine, Tokyo University Hospital, (3)Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, (4)Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S580-S580, 2010.

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P10-2-1 A case of medullary thyroid carcinoma showing ectopic acth syndrome with multi-organ metastasis

Yuichiro Yoshikawa(1), Takashi Iwamoto(1), Hiroko Abe(1), Narihiro Furugaki(1), Shigeki Imamura(1), Hideki Katagami(2), Hironobu Sasano(3), Takashi Kishimoto(4), Aizan Hirai(1)
(1)Division of Endocrinology and Metabolism, Department of Internal Medicine, Chiba Prefectural Togane Hospital, (2)Division of Clinical Investigation, Department of Internal Medicine, Teikyo University Chiba Medical Center, (3)Departmant of Pathology, Tohoku University School of Medicine, (4)Department of Molecular Pathology, Chiba University Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S580-S580, 2010.

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P10-2-2 Small cell lung cancer with ectopic ACTH secretion

Yahui Hu
Department of Endocrinology and Metabolism, Buddhist Tzu Chi General Hospital Taipei Branch
ENDOCRINE JOURNAL 57 (suppl.2-2) S580-S580, 2010.

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P10-2-3 Small cell carcinoma of the endometrium presenting as Cushing syndrome

Haruhiro Sato(1), Robert Y Osamura(2)
(1)Internal Medicine, Toakai University School of Medicien, (2)Pathology, Tokai University School of Medicien
ENDOCRINE JOURNAL 57 (suppl.2-2) S580-S580, 2010.

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P10-2-4 Ectopic ACTH syndrome associated with adenocarcinoma of the rectum

Mai Asano, Akiyo Tanabe, Mika Tsuiki, Naomi Hizuka, Kazue Takano
Institute of Clinical Endocrinology, Department of Medicine, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S580-S581, 2010.

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P10-2-5 Ectopic ACTH syndrome in children and adolescents

Antoine Tabarin(1), Julie More(1), Yves Reznik(2), Regis Coutant(3), Francoise Borson(4), Eric Baudin(5), Aurelien Marabelle(4), Vincent Rohmer(3), (6), Jacques Young(6)
(1)Dpt Of Endocrinology, University Hospital of Bordeaux, (2)Dpt.of Endocrinology, CHU de Caen, (3)Dpt of Endocrinology-CHU de Angers, (4)Dpt of Endocrinology-Hospices Civils de Lyon, (5)Dpt of Endocrine Oncology.Institut Gustave Roussy.Paris, (6)Dpt of Endocrinology-CHU Kremlin Bicetre.Paris
ENDOCRINE JOURNAL 57 (suppl.2-2) S581-S581, 2010.

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P10-2-6 Ectopic ACTH-producing carcinoid tumor of unknown origin:An autopsy case report

Ikuo Yamamori(1), Yuichiro Yamauchi(1), Takashi Murase(1), Masako Yamauchi(1), Kouichi Adachi(1), Makoto Ikeniwa(1), Masafumi Ito(2)
(1)Department of Endocrinology and Metabolism, Japanese Red Cross Nagoya Daiichi Hospital, (2)Department of Pathology, Japanese Red Cross Nagoya Daiichi Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S581-S581, 2010.

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P10-2-7 Possible positive feedback by glucocorticoid(GC)observed both in vivo and in vitro in a case with ectopic ACTH syndrome(EAS)

Hiroshi Koso(1), Koji Morita(1), Mieno Konishi(1), Kunihisa Hamano(1), Hisatoshi Asano(2), Yuichi Ozeki(2), Fumihiko Kimura(3), Yuji Tanaka(1)
(1)Department of Internal Medicine, Division of Endocrinology and Metabolism, National Defense Medical College, (2)Department of Surgery, National Defense Medical College, (3)Department of Internal Medicine, National Defense Medical College
ENDOCRINE JOURNAL 57 (suppl.2-2) S581-S581, 2010.

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P10-3-1 Multiple endocrine neoplasia(MEN)type 1 in Japan:Establishment and analysis of a multicenter database

Shinichi Suzuki(1), (5), Akihiro Sakurai(2), (5), Shinya Uchino(3), (5), Masayuki Imamura(4), (5)
(1)The Department of Breast Endocrine Thyroid Surgery, Fukushima Medical University, (2)Department of Medical Genetics, Shinshu University School of Medicine, (3)Noguchi Thyroid Clinic and Hospital Foundation, (4)Department of Surgery, Osaka Saiseikai Noe Hospital, (5)MEN consortium of Japan
ENDOCRINE JOURNAL 57 (suppl.2-2) S581-S582, 2010.

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P10-3-2 Novel MEN1 gene mutation in a family with multiple endocrine neoplasia type 1

Jeong Seon Yoo(1), Min Ho Cho(1), Chul sik Kim(2), Woo-ho Shim(1), Eun-Hae Lee(1), Tae-Woong Noh(1), Jong Eun Lee(3), Ji Sun Nam(1), Jong Suk Park(1), Chul Woo Ahn(1), Eun Jig Lee(1), Kyung Rae Kim(1)
(1)Department of Internal Medicine, Yonsei University College of Medicine, (2)Department of Internal Medicine, Hallym University College of Medicne, (3)DNA link.Co
ENDOCRINE JOURNAL 57 (suppl.2-2) S582-S582, 2010.

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P10-3-3 GHRH producing neuroendocine pancreatic tumor in MEN1 with large deletion of MEN1 gene

Chika Watanabe(1), (5), (6), Yuko Yambe(1), Takeshi Usui(2), Toshihiko Sano(3), Shigeru Hagimoto(1), Tsutomu Yamada(1), Mitsuro Niinomi(1), Soshun Takada(4), Hideaki Maruse(7), Hiroyuki Higashi(7), Mitsuhide Naruse(2), Akira Shimatsu(2), Yasuhisa Kato(1)
(1)Department of Endocrinology and Diabetes, National Hospital Organization Nagoya Medical Center, (2)Clinical Institute, National Hospital Organization Kyoto Medical Center, (3)Department of Human Pathology, Institute of Health Biosciences, University of Tokushima Graduate School, (4)Department of Neurosurgery, National Hospital Organization Nagoya Medical Center, (5)Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, (6)Research Institute of Environmental Medicine, Nagoya University, (7)Biomedical Business Division, Genetic Testing Deptartment, FALCO biosystems Ltd
ENDOCRINE JOURNAL 57 (suppl.2-2) S582-S582, 2010.

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P10-3-4 Profile of genes in cells expressing wild-type and A242V menin

Ryo Taguchi, Masanobu Yamada, Kazuhiko Horiguchi, Atsushi Ozawa, Koshi Hashimoto, Tetsurou Satoh, Masatomo Mori
Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S582-S582, 2010.

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P10-3-5 Analysis of messenger RNA level of p18INK4, P27Kip1, MEN1 and RET in thyroid tumors

Atsushi Ozawa(1), Masanobu Yamada(1), Yukio Koibuchi(2), Jun Horiguchi(2), Nobuyuki Shibusawa(1), Koshi Hashimoto(1), Tetsurou Satoh(1), Masatomo Mori(1)
(1)Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, (2)Department of Thoracic Visceral Organ Surgery, Gunma University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S582-S583, 2010.

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P10-3-6 Inhibition of Arginase II mediates apoptosis in follicular thyroid carcinoma cell line

Maria Sharmila A.Souza, Flavia M.R.Latini, Hugo P.Monteiro, Janete M.Cerutti
Federal University of Sao Paulo
ENDOCRINE JOURNAL 57 (suppl.2-2) S583-S583, 2010.

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P10-3-7 Upregulated adenosine receptor A1(ADORA1)modulates matrix metalloproteinases secretion in thyroid carcinomas

Tetsuo Kondo, Tadao Nakazawa, Defu Ma, Dongfeng Niu, Tomonori Kawasaki, Kunio Mochizuki, Tetsu Yamane, Ryohei Katoh
Department of Pathology, University of Yamanashi
ENDOCRINE JOURNAL 57 (suppl.2-2) S583-S583, 2010.

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P10-3-8 Contribution of integrin(alpha6beta4)to thyroid carcinoma progression

Tae-Woong Noh(1), Hong Im Kim(4), Young Hwa Soung(4), Woo Ick Yang(3), Jeong Mo Kim(1), Eun Jig Lee(1), (2), Jun Chung(4)
(1)Department of endocrinology, internal medicine Yonsei University, (2)Biochemistry and Molecular Biology Yonsei University College of Medicine, (3)Department of pathology.Yonsei University College of Medicine, (4)Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S583-S583, 2010.

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P10-4-1 Nycthemeral melatonin rhythm before and after surgery in patients with tumors of the pineal region

Michelle Fevre Montange(1), (2), (3), (4), Jose Leston(2), Jacques Champier(1), Carmine Mottolese(2), Guy Chazot(2), Bruno Claustrat(3), Anne Jouvet(4)
(1)Inserm U842, Faculte de Medecine Laennec, Universite de Lyon, (2)Service de Neurochirurgie et de Neurologie, Groupement Hospitalier Est, (3)Service Hormonologie, INSERM U846, Groupement Hospitalier Est, (4)Centre de Pathologie Est, Groupement Hospitalier Est
ENDOCRINE JOURNAL 57 (suppl.2-2) S583-S583, 2010.

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P10-4-2 Evaluation of therapeutic results and complications in gamma knife radiosurgery for acromegaly

Satoshi Tanaka(1), Izumi Fukuda(1), Naomi Hlzuka(1), Makiko Kurimoto(1), Yu Yamakado(1), Motohiro Hayashi(2), Masahiro Izawa(2), Tomokatsu Hori(2), Kazue Takano(1)
(1)Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical Univercity, (2)Department of neurosurgery, Tokyo Women's Medical Univercity
ENDOCRINE JOURNAL 57 (suppl.2-2) S584-S584, 2010.

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P10-4-3 Recurrent hyperinsulinemic hypoglycemia in a 23 year-old male with negative imaging studies:enigma of insulinoma

Michelle V.Lemoncito(1), Cindy V.Josol(1), Hallert C.Ramos(1), Joselynna A.Quimpo(1), Frances Lina L.Ang(1), Ma.Luz Vicenta V.Guanzon(2)
(1)Section of Endocrinology, Diabetes & Metabolism, University of the Philippines-Philippine General Hospital, (2)Riverside Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S584-S584, 2010.

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P10-4-4 Gene expressions of proprotein convertase 4 and furin in tumors causing non-islet cell tumor hypoglycemia

Atsushi Nakagawa(1), Noriko Imaizumi(1), Makoto Nishizawa(1), Keigo Uehara(1), Tomoki Fukuyama(2), Tomiyasu Arisawa(2), Kazuhide Ishikura(3), Toshinari Takamura(3), Shuichi Kaneko(3), Daisuke Koya(1)
(1)Department of Endocrinology and Metabolism, Kanazawa Medical University, (2)Department of Gastroenterology, Kanazawa Medical University, (3)Department of Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Science
ENDOCRINE JOURNAL 57 (suppl.2-2) S584-S584, 2010.

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P10-4-5 Eus-guided fine needle tattooing(EUS-FNT)for preoperative localization of small pancreatic neuroendocrine tumors:a single center experience

Alberto Iarghi(1), Francesca Lugli(2), Alessandra Fusco(2), Antonio Bianchi(2), Sergio Alfieri(3), Marco Raffaelli(3), Celestino Pio Lombari(3), Rocco Bellantone(3), Giovanni Battista Doglietto(3), Duido Costamagna(3), linda tartaglione(2), Alfredo Pontecorvi(2), Laura De Marinis(2)
(1)digestive Endoscopy Unit, Catholic University, (2)Endocrinology Unit Catholic University, (3)department of Surgery, Catholic University
ENDOCRINE JOURNAL 57 (suppl.2-2) S584-S585, 2010.

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P10-4-6 Treatment of gastroenteropancreatic neuroendocrine tumours(GEP-NET)consisted of lanreotide(Somatuline Autogel)after 90Y-and/or 177Lu-DOTA-TATE therapy

Norbert Szalus(1), Grzegorz W.Kaminski(2), Zbigniew Podgajny(2), Eugeniusz Dziuk(1), Joanna Cyperling-Kaminska(1)
(1)Dpt.of:Nuclear Medicine, Military Institute of Health Services Warsaw, (2)Endocrinology and Radioisotope Therapy, Military Institute of Health Services Warsaw
ENDOCRINE JOURNAL 57 (suppl.2-2) S585-S585, 2010.

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P10-4-7 Radiolabelled somatostatin analogues in the treatment of neuroendocrine cancers

Daria Handkiewicz-Junak, Jozef Roszkosz, Kormelia Hasse-Lazar, Beata Jurecka-Lubieniecka, Jolanta Krajewska, Barbara Jarzab
Nuclear Medicine and Endocrine Oncology Department, Maria Sklodowska Curie Memorial Cancer Center and Institute of Oncology
ENDOCRINE JOURNAL 57 (suppl.2-2) S585-S585, 2010.

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P10-4-8 Plants are popularly used by alternative medicinal practitioners of Kishoreganj district, Bangladesh to treat cancer, hypertension, heart diseases, diabetes, and rheumatoid arthritis

M.A.H.Mollik(1), M.R.Faruque(1), R.McField(1), K.Akter(1), A.Chowdhury(2), D.Sen(2), K.K.Thapa(3), A.I.Hassan(4), M.T.Islam(4)
(1)Department of Epidemiology, Biostatistics, Community Nutrition and Noncommunicable Diseases, Peoples Integrated Alliance, (2)Department of Health Technology[Laboratory], State College of Health Sciences, (3)Department of Botany, Dinhata College, (4)Department of Health and Nutrition, Biogene Life Care
ENDOCRINE JOURNAL 57 (suppl.2-2) S585-S585, 2010.

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P10-5-1 Distinct uptake of 18F-fluorodeoxyglucose by brown adipose tissue in catecholamine-secreting tumor

Naoko Sekizawa, Hajime Izumiyama, Takanobu Yoshimoto, Yukio Hirata
Department of Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate School
ENDOCRINE JOURNAL 57 (suppl.2-2) S585-S586, 2010.

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P10-5-2 Morbus von Hippel-Lindau-a disease with variable clinical picture

Juraj Payer(1), Patricia Palenikova(1), Peter Jackuliak(1), Beata Ftacnikova(2), Ladislav Kuzela(3)
(1)The 5th Department of Internal Medicine, Medical Faculty of Comenius University, Faculty Hospital Bratislava, (2)Department of Radiology, Faculty Hospital Bratislava, (3)Department of Gastroenterology, Medical Faculty of Comenius University, Faculty Hospital Bratislava
ENDOCRINE JOURNAL 57 (suppl.2-2) S586-S586, 2010.

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P10-5-3 A case of succinate dehydrogenase B(SDHB)-associated malignant paraganglioma with multidisciplinary treatment

Katsutoshi Kojima(1), Naohisa Tamura(1), Toshiyuki Kitano(2), Takeshi Usui(3), Takuhiro Sonoyama(1), Masakatsu Sone(1), Yasutomo Fukunaga(1), Daisuke Taura(1), Megumi Inuzuka(1), Masako Miura(1), Naotetsu Kanamoto(1), Akihiro Yasoda(1), Hiroshi Arai(1), Makoto Sonobe(4), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Outpatient Oncology Unit, Kyoto University Hospital, (3)Clinical Research Institute, Division of Endocrinology and Metabolism, National Hospital Organization Kyoto Medical Center, (4)Department of Thoracic Surgery, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S586-S586, 2010.

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P10-5-4 Mutation analysis of SDHB and SDHD gene in pheochromocytomas and paragangliomas:identification of a novel nonsense mutation(Q168X)

Chikara Shimizu(1), (2), Yohmi Oishi(1), So Nagai(2), Miyuki Yoshida(1), Shin-ichi Fujisawa(1), Ataru Sazawa(3), Nobuo Shinohara(3), Katsuya Nonomura(3), Kazuhiko Matsuno(1)
(1)Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, (2)Department of Medicine II, Hokkaido University Hospital, (3)Department of Urology, Hokkaido University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S586-S586, 2010.

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P10-5-5 Neurofibromatosis type 1(NF 1)and bilateral pheochromocytoma(PCC)with long-term metastases on gastrointestinal stromal tumor(GIST)presented as a neuroendocrine tumor(NET)

Concha Sanabria(1), Jose Angel Diaz Perez(1), Luis Ortega(2), Natalia Perez Ferre(1), Luis Diez Valladares(3), Mercedes Robledo(4)
(1)Department of Endocrinology and Nutrition, San Carlos Clinic Hospital, (2)Department of Pathology.San Carlos Clinic Hospital, (3)Department of Surgery.San Carlos Clinic Hospital, (4)CNIO
ENDOCRINE JOURNAL 57 (suppl.2-2) S586-S587, 2010.

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P10-5-6 Side-effects and response to the radioisotope 90Y/177Lu DOTA-TATE therapy in patients with disseminated NET-Do repeated cycles of PRRT increase toxicity of the therapy?

Anna Sowa-Staszczak(1), Alicja B.Hubalewska-Dydejczyk(1), Agnieszka Stefanska(1), Jolanta Kunikowska(2), Leszek Krolicki(2), Dorota Pach(1), Renata Mikolajczak(3), Dariusz Pawlak(3), Malgorzata Trofimiuk(1)
(1)Endocrinology Department, Nuclear Medicine Unit, Medical College, Jagiellonian University, (2)Nuclear Medicine Department, Medical Academy, (3)Research and Development, IAE Radioisotope Centre POLATOM
ENDOCRINE JOURNAL 57 (suppl.2-2) S587-S587, 2010.

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P10-5-7 Clinical and radiological efficacy i.a. 90Y-DOTATATE therapy in patients with advance, progressive neuroendocrine carcinomas

Jaroslaw B.Cwikla(1), Miroslaw L.Nowicki(2), Artur J.Sankowski(2), Anna Lewczuk(3), Nina Seklecka(2), John R.Buscombe(4), Anna Nasierowska-Guttmejer(5), Renata Mikolajczak(6), Dariusz Pawlak(6), Jerzy Walecki(1)
(1)Department of Radiology and Diagnostic Imaging, Medical Centre for Postgraduate Education, (2)Department of Radiology and Diagnostic Imaging Hospital Ministry of Internal Affairs & Administration, (3)Department of Nuclear Medicine, Royal Free Hospital, (4)Department of Endocrinology and Haemostatic Disorders, Medical University, (5)Department of Pathology, Hospital Ministry of Internal Affairs & Administration, (6)IAE, Radioisotope Centre POLATOM
ENDOCRINE JOURNAL 57 (suppl.2-2) S587-S587, 2010.

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P10-5-8 Acute inflammatory syndrome and intrahepatic cholestasis caused by an interleukin-6-producing pheochromocytoma with pregnancy

Kenji Ashida(1), Ryoko Nagaishi(1), Yuko Akehi(1), Keizo Anzai(1), Kazuna Higuchi(2), Takeshi Nojiri(3), Mikiko Aoki(4), Kazuki Nabeshima(4), Masatoshi Tanaka(2), Junko Ono(5), Toshihiko Yanase(1)
(1)The Department of Endocrinology and Diabetes mellitus, School of medicine, Fukuoka University, (2)Department of Urology, School of medicine, Fukuoka University, (3)Department of Obstetrics and Gynecology, School of medicine, Fukuoka University, (4)Department of Pathology, School of medicine, Fukuoka University, (5)Murakamikarindo hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S587-S587, 2010.

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P10-6-1 Insulinoma with initial presentation of seizure

Ming-Min Chung
Division of Endocrinology and Metabolism, department of Internal Medicine, Far Eastern Memorial Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S588-S588, 2010.

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P10-6-2 A use of insulinoma showing reduction of blood flow in hippocampus after hypoglycemia

Hiroki Takahashi, Hiroyuki Shimizu, Koshi Hashimoto, Shuichi Okada, Takafumi Tuchiya, Tugumichi Saito, Aya Ohsaki, Yutaka Uehara, Tetsurou Satoh, Masanobu Yamada, Masatomo Mori
Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S588-S588, 2010.

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P10-6-3 Non-islet cell tumor hypoglycemia(NICTH)in retroperitoneal solitary fibrous tumor

Masahiro Miyawaki(1), Hisashi Imbe(1), Megumi Bessho(1), Yoshie Go(1), Haruko Kitaoka(1), Atsunari Kawashima(2), Izumi Fukuda(3), Naomi Hizuka(3), Motohiko Aiba(4)
(1)The Department of Internal Medicine, Seikeikai Hospital, (2)The Department of Urology, Osaka Rosai Hospital, (3)Department of Medicine II, Tokyo Women's Medical University, (4)Department of pathology, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S588-S588, 2010.

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P10-6-4 Malignant glucagonoma in a patient with diabetes mellitus and Prader-Willi syndorome treated with Glargine

Keisuke Yoshii, Masahiro Noda, Kiyomi Abe, Yasuhiro Naiki, Reiko Horikawa
Division of Endocrinology and Metabolism, National Center for Child Health and Development
ENDOCRINE JOURNAL 57 (suppl.2-2) S588-S588, 2010.

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P10-6-5 Microarray analysis of altered gene expression in PPAR-pan agonist-treated pancreatic cancer cells

Mayumi Sato(1), Kiyoshi Ogura(1), Yasumasa Nishitho(1), Hiroyuki Miyachi(2)
(1)Division of molecular pathology, The Tokyo Metropolitan Institute of Medical Science, (2)Graduate School of Medicine, Dentistry & Pharmaceutical, Okayama University
ENDOCRINE JOURNAL 57 (suppl.2-2) S588-S589, 2010.

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P10-6-6 Tumor growth inhibition after Pasireotide(SOM230)in a rat prostate tumor model(DU-145)alone and in combination with Everolimus(RAD001)

Herbert A.Schmid, Nuciforo Paolo
Novartis Institutes for Biological Research
ENDOCRINE JOURNAL 57 (suppl.2-2) S589-S589, 2010.

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P10-6-7 Vitamin d derivatives and plant antioxidants in combination therapy of acute myeloid leukemia:translational studies

Michael Danilenko(1), George P.Studzinski(2)
(1)Department of Clinical Biochemistry, Ben-Gurion University of the Negev, (2)Department of Pathology & Laboratory Medicine, UMD-New Jersey Medical School
ENDOCRINE JOURNAL 57 (suppl.2-2) S589-S589, 2010.

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P10-6-8 Differential expression of haemostasis system genes and prothrombotic cytokines in patients with myeloproliferative disorders

Lakshmi Kannan, Mary F.McMullin, Paul C.Winter
Department of Haematology, Belfast City Hospital, Queens University Belfast
ENDOCRINE JOURNAL 57 (suppl.2-2) S589-S589, 2010.

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P10-7-1 Phosphate activated glutaminase(GLS2), a novel p53-dependent regulator of glutamine metabolism and reactive oxygen species

Sawako Suzuki, Tomoaki Tanaka, Hidekazu Nagano, Kotaro Yokote, Ichiro Tatsuno
Clinical Cell Biology, Chiba University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S589-S590, 2010.

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P10-7-2 Transcriptional coactivator sp110 associates with p53 and regulates p53-dependent cellular senescence

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P10-7-3 Novel function of tumor suppressor p53 in the regulation of cell metabolism in human preadipocytes and endotherial cells(EC)

Hidekazu Nagano, Tomoaki Tanaka, Kotaro Yokote, Ichiro Tatsuno
Dept.Clinical Cell Biology, Chiba Univ., Graduate School of Medecine
ENDOCRINE JOURNAL 57 (suppl.2-2) S590-S590, 2010.

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P10-7-4 Nuclear export factor hcas/cse 1l associates with chromatin and regulates expression of selective p53 target genes

Tomoaki Tanaka, Kotaro Yokote, Ichiro Tatsuno
Dept.Clinical Cell Biology, Chiba Univ., Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S590-S590, 2010.

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P10-7-5 Role of the tumoral GHRH receptor in the cell proliferation

Zoltan Rekasi(1), Tamas Czompoly(2), Peter Balogh(2), Ferenc Boldizsar(2), Diana Simon(2), Krisztian Kvell(2), Terezia Laszlo(3), Katinka Orosz(2), Marta Zarandi(4), Jozsef L Varga(5), Peter Nemeth(2), Andrew V Schally(5)
(1)Department of Anatomy, University of Pecs, (2)Department of Immunology and Biotechnology, University of Pecs, (3)Department of Pathology, University of Pecs, (4)Department of Medical Chemistry, University of Szeged, (5)Endocrine, Polypeptide and Cancer Institute, Veterans Affairs Medical Center and South Florida VA Foundation for Research and Education
ENDOCRINE JOURNAL 57 (suppl.2-2) S590-S591, 2010.

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P10-7-6 Sp1 is a transcription repressor to stanniocalcin-1 gene expression in human colon cancer cells, HT29

Yu Sheung Law, Chris K.C.Wong
Department of Biology, Hong Kong Baptist University
ENDOCRINE JOURNAL 57 (suppl.2-2) S591-S591, 2010.

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P10-7-7 Effects of cell-density and focal adhesion kinase to stanniocalcin-1 expression in human cancer cells

Lai Yin Ching, Chris K.C.Wong
Hong Kong Baptist University
ENDOCRINE JOURNAL 57 (suppl.2-2) S591-S591, 2010.

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P10-7-8 Development of adenovirus vectors for targeted gene therapy of craniopharyngiomas

Toshiro Seki, Nobuhiro Miki, Masami Ono, Rena Makino, Kazue Takano
Department of Medicine II, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S591-S591, 2010.

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P10-8-1 Diagnostic and prognostic value of steroidogenic factor 1(SF-1)in adrenal tumors

Martin Fassnacht(1), Silviu Sbiera(1), Sebastian Schmull(1), Guillaume Assie(2), Hans-Ullrich Voelker(1), Bruno Ragazzon(2), Felix Beuschlein(3), Holger S.Willenberg(4), Stefanie Hahner(1), Jerome Bertherat(2), Bruno Allolio(1)
(1)Dept.of Medicine, University of Wuerzburg, (2)Institut Cochin, University Descartes, (3)Department of Medicine-Endocrinology, Medizinische Klinik Innenstadt, University of Munich, (4)Department of Endocrinology, Diabetes and Rheumatology, University Hospital Duesseldorf
ENDOCRINE JOURNAL 57 (suppl.2-2) S591-S591, 2010.

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P10-8-2 The significance of CXCR4 expression on Adrenocortical carcinoma

Li Jiang(1), ZuoJie Luo(2), XiaoCong Kuang(3), XingHuan Liang(2), Yinfen Qin(2), DeCheng Lu(2)
(1)Graduate School, Guangxi Medical University, (2)Endocrine Department of 1st affiliate hospital, Guangxi Medical University, (3)Pathopysiology Department, Guangxi Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S592-S592, 2010.

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P10-8-3 Clinicopathological features and gene expression profile in adrenocortical carcinoma

Ryuji Kouyama(1), Kiichiro Hiraishi(1), Hajime Izumiyama(1), Takanobu Yoshimoto(1), Takumi Akashi(2), Kazunori Kihara(3), Keiko Homma(4), Hirotaka Shibata(5), Hironobu Sasano(6), Yukio Hirata(1)
(1)Department of Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate School, (2)Department of Pathology, Tokyo Medical and Dental University Graduate School, (3)Department of Urology, Tokyo Medical and Dental University Graduate School, (4)Central Clinical Laboratories, Keio University Hospital, (5)Department of Internal Medicine, Keio University, School of Medicine, (6)Department of Pathology, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S592-S592, 2010.

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P10-8-4 The preliminary prevalence analysis of adrenal tumors and secondary hypertension in patients with hypertension

Xiaomu Li
Department of Endocrinology, Zhongshan Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S592-S592, 2010.

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P10-8-5 A case of adult nesidioblastosis associated with adrenal hyperplasia

Junko Kawahara, Hiroyuki Takata, Yoshio Hiraiwa
The Internal Medicine, Toyama Red Cross Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S592-S592, 2010.

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P10-8-6 Regulation of aromatase expression by intratumoral stromal cell-derived factors in lung carcinoma cells

Yasuhiro Miki(1), Takashi Suzuki(1), Keiko Abe(1), Satoshi Suzuki(2), Shuko Hata(1), Jun-ichi Akahira(1), Hironobu Sasano(1)
(1)Department of Pathology, Tohoku University Graduate School of medicine, (2)Department of Thoracic Surgery, Ishinomaki Red Cross Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S592-S593, 2010.

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P10-8-7 Expression of steroid sulfatase in human non-small cell lung carcinoma

Hideaki Kakinuma(1), Yasuhiro Miki(1), Keiko Abe(1), Satoshi Suzuki(3), Jun-ichi Akahira(1), Takashi Suzuki(2), Hironobu Sasano(1)
(1)Department of Pathology, Tohoku University Graduate School of Medicine, (2)Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine, (3)Department of Respiratory Surgery, Ishinomaki Red Cross Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S593-S593, 2010.

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P10-8-8 Effect of eplerenone, a selective aldosterone blocker, on severe hypokalemia in a patient with big IGFII-producing non-islet cell tumor

Shigehiro Karashima, Mitsuhiro Kometani, Masashi Ohe, Masashi Demura, Shunsuke Mori, Takashi Yoneda, Yoshiyu Takeda
Department of Internal Medicine, Graduate School of Medical Science, Kanazawa University
ENDOCRINE JOURNAL 57 (suppl.2-2) S593-S593, 2010.

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P11-1-1 New strategy for treatment of endometriosis using oral contraceptive pills(OC)

Kohzo Aisaka(1), Haruko Hiraike(1), Yumiko Ikezuki(1), Seiichiro Obata(1), Hiroyuki Mori(2)
(1)Department of Obstetrics and Gynecology, Hamada Hospital, (2)Department of Obstetrics and Gynecology, Teikyo University
ENDOCRINE JOURNAL 57 (suppl.2-2) S593-S593, 2010.

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P11-1-2 Progesterone is a key player for the growth maintenance of uterine leiomyoma

Hiroshi Ishikawa(1), Kazutomo Ishi(2), Makio Shozu(1), Serdar E.Bulun(2), Takeshi Kurita(2)
(1)Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, (2)Division of Reproductive Biology Research, Department of Obstetrics and Gynecology, Feinberg School of Medicine at Northwestern University
ENDOCRINE JOURNAL 57 (suppl.2-2) S593-S594, 2010.

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P11-1-3 Clomiphene citrate causes aberrant stromal cell-specific apoptosis in the rat uterus

Ruijin Shao, Emil Egecioglu, Hakan Billig
Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg
ENDOCRINE JOURNAL 57 (suppl.2-2) S594-S594, 2010.

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P11-1-4 Transforming growth factor-α regulates insulin-like growth factor binding protein-3 gene expression in the mouse endometrial stromal cells

Sumio Takahashi(1), Tetsuya Maekawa(1), Atsuko Sakuma(1), Shusuke Taniuchi(1), Munetoshi Kanayama(1), Taisen Iguchi(2), Sakae Takeuchi(1)
(1)Department of Integrative Biology, Graduate School of Natural Science and Technology, Okayama University, (2)Division of Molecular Environmental Endocrinology, Department of Environmental Biology, National Institute for Basic Biology
ENDOCRINE JOURNAL 57 (suppl.2-2) S594-S594, 2010.

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P11-1-5 Decreased expression of IGF1 and TGFα mRNAs in the uterus of streptozotocin-induced diabetic mice

Makoto Tochigi(1), Yoshie Manabe(2), Akiyoshi Moriwaki(2), Munetoshi Kanayama(1), Sakae Takeuchi(1), Sumio Takahashi(1)
(1)Department of Integrative Biology, Graduate School of Natural Science and Technology, Okayama University, (2)Department of Human Nutrition, Faculty of Contemporary Life Science, Chugoku Gakuen University
ENDOCRINE JOURNAL 57 (suppl.2-2) S594-S594, 2010.

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P11-1-6 The effects of levonorgestrel, fulvestrant and progesterone on human endometrial cell growth in vitro

Uzmah J.Sabar(1), Debbie P.Fischer(1), Diane Farrar(2), Peter J.O'Donovan(2), David F.Woodward(3), Kay M.Marshall(1)
(1)Bradford School of Pharmacy, University of Bradford, (2)Bradford Royal Infirmary, Duckworth Lane, (3)Department of Biological sciences, Allergan Inc
ENDOCRINE JOURNAL 57 (suppl.2-2) S594-S595, 2010.

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P11-1-7 Rho-kinase mediates oxytocin signalling in human myometrial cells

Debbie P.Fischer(1), Diane Farrar(2), Peter J.O'Donovan(2), David F.Woodward(3), Kay M.Marshall(1)
(1)Bradford School of Pharmacy, University of Bradford, (2)Bradford Royal Infirmary, (3)Department of Biological Sciences, Allergan
ENDOCRINE JOURNAL 57 (suppl.2-2) S595-S595, 2010.

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P11-1-8 Intraperitoneal dioxin concentration is high in endometriosis patitents

Eri Nakamura, Masaru Hayashi, Taro Sugiyama, Ken-ichi Goya, Takayo Murano, Takahiro Suzuki, Shun-ichiro Izumi
Specialized Clinical Science, Tokai University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S595-S595, 2010.

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P11-1-9 Estrogen receptor-alpha(ESR1)gene polymorphisms and endometriosis

Akane Kondo, Yumiko Goto, Yoshihiro Nishijima, Kazumi Takahashi, Atsuko Togo, Tadashi Matsumoto, Shun-ichiro Izumi
Obstetrics and Gynecology, Tokai University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S595-S595, 2010.

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P11-2-1 Successful pregnancies in four women with premature ovarian failure resulting from close monitoring of follicle development during long-term follow-up

Tetsuo Maruyama, Hideyuki Oda, Sayaka Nishikawa, Maki Kagami, Kaoru Miyazaki, Hiroshi Uchida, Yasunori Yoshimura
Department of Obstetrics and Gynecology, School of Medicine, Keio University
ENDOCRINE JOURNAL 57 (suppl.2-2) S595-S596, 2010.

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P11-2-2 Follicular development and secretory activity of corpus luteum and placenta during pregnancy in goats

Mohamed Kandiel(1), Gen Watanabe(1), (2), (3), Abd El-Salam El-Azab(5), Alaa Abd El-Ghaffar(5), Gamal Sosa(5), Mahmoud Abou-El Roos(5), Jun Li(4), Noboru Manabe(4), Kazuyoshi Taya(1), (2)
(1)Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, (2)Tokyo University of Agriculture and Technology, (3)Department of Basic Veterinary Science, The united Graduated School of Veterinary Sciences, Gifu University, (4)Animal Resource Science Center, Graduated School of Agriculture and Life Science, University of Tokyo, (5)Faculty of Veterinary Medicine, Benha University
ENDOCRINE JOURNAL 57 (suppl.2-2) S596-S596, 2010.

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P11-2-3 Endocrine mechanisms responsible for different ovarian follicular development during the estrous cycle between high-and low-avoidance Hatano rats

Yasuyuki Horii(1), (2), Sukanya Jaroenporn(3), Sayaka Asai(4), KaiMing Wang(2), Ryo Ohta(5), Mariko Shirota(6), Gen Watanabe(1), (2), Kazuyoshi Taya(1), (2)
(1)Department of Basic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, (2)Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, (3)Primate Research Unit Department of Biology, Faculty of Science, Chulalongkorn University, (4)Department of Internal Medicine, Miyazaki Medical College, University of Miyazaki, (5)Safety Testing Laboratory, Research Administration, Hatano Research Institute, Food and Drug Safety Center, (6)Laboratory of Comparative Toxicology, School of Veterinary Medicine, Azabu University
ENDOCRINE JOURNAL 57 (suppl.2-2) S596-S596, 2010.

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P11-2-4 Tissue glucose utilization in normal body weight and obese women with polycystic ovarian syndrome

Magdalena Sendrakowska(1), Jozef Krzysiek(1), Andrzej Zmaczynski(1), Tomasz Milewicz(1), Alicja Hubalewska-Dydejczyk(2), Aleksandra Gilis-Januszewska(2)
(1)Department of Gynecological Endocrinology Jagiellonian University Medical College, (2)Department of Endocrinology Jagiellonian University Medical College
ENDOCRINE JOURNAL 57 (suppl.2-2) S596-S596, 2010.

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P11-2-5 Usefulness of bezafibrate for ovulation induction in clomiphene citrate-resistant polycystic ovary syndrome patients with dyslipidemia:a case series of 7 patients

Toshifumi Takahashi, Shuichiro Hara, Mitsuyoshi Amita, Hideki Igarashi, Hirohisa Kurachi
Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S596-S597, 2010.

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P11-2-6 Phenotype and metabolic disorders in polycystic ovary syndrome

Olgierd Gluszak(1), Urszula Stopinska-Gluszak(1), Piotr Kretowicz(2), Romuald Debski(2)
(1)Clinic of Endocrinology and Internal Medicine CMKP, Bielanski Hospital, (2)Clinic of Obstetrics and Gynaecology CMKP, Bielanski Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S597-S597, 2010.

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P11-2-7 Studying of ovarian activity and pregnancy rate after eCG administration during the beginning of non-breeding season by using of ultrasonography in Iranian Shall ewes

Hamed Kermani Mokar, Hamid Kohram, Ahmad Zare Shahne
The Department of Animal Science, University of Tehran
ENDOCRINE JOURNAL 57 (suppl.2-2) S597-S597, 2010.

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P11-2-8 Human luteal cells express monoamine oxidase-A during early pregnancy

Yumi Takao(1), Hiroshi Fujiwara(1), Masamichi Ueda(2), Akihito Horie(1), Ikuo Konishi(1)
(1)Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, (2)Institute for Virus Research, Kyoto University
ENDOCRINE JOURNAL 57 (suppl.2-2) S597-S597, 2010.

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P11-3-1 Effects of gestational diethylstilbestrol treatment on gonadal differentiatio

Yayoi Ikeda, Tomoko Kato, Masahito Takiguchi
Department of Histology and Cell Biology, Yokohama City University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S597-S597, 2010.

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P11-3-2 Diagnosis and management of women with DSD(disorder of sex development)

Tomonari Hayama, Aiko Kawano, Reiko Nakamura, Yuko Tagami, Ryoko Asano, Akiko Nara, Yasuko Suzuki, Tomoko Nagata, Yoshiyuki Nomura, Kazuko Sumitomo, Mariko Murase, Maki Takei, Hideya Sakakibara, Fumiki Hirahara
Department of Obstetrics and Gynecology, Yokohama City University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S598-S598, 2010.

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P11-3-3 Measurement of human newborn anogenital distance and evaluation of exposure to environmental chemicals on human reproductive system

Yoshifumi Mizumoto(1), Mitutaka Murakami(1), Kenich Furuya(2), Yayoi Suzuki(3), Jun Yoshinaga(3)
(1)The Department of Obstetrics and Gynecology, Self Defense Forces central hospital, (2)The Department of Obstetrics and Gynecology, National Defense Medical College, (3)The Department of Environmental Studies, University of Tokyo
ENDOCRINE JOURNAL 57 (suppl.2-2) S598-S598, 2010.

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P11-3-4 The role of fibroblast growth factor(FGF)9, FGF10 and sonic hedgehog on the cell proliferation and differentiation of vaginal epithelium of neonatal mice

Tadaaki Nakajima(1), Taisen Iguchi(2), Tomomi Sato(1)
(1)The Department of Genome System Science, Yokohama City University, (2)The National Institutes of Natural Sciences, Graduate University for Advanced Studies and Okazaki Institute for Integrative Bioscience
ENDOCRINE JOURNAL 57 (suppl.2-2) S598-S598, 2010.

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P11-3-5 Involvement with gonadotropins in the hypertrophy in the ovarian interstitial tissue of neonatally DES treated female mice

Hanako Kakuta, Tomomi Sato
International Graduate School of Arts and Sciences, Yokohama City University
ENDOCRINE JOURNAL 57 (suppl.2-2) S598-S598, 2010.

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P11-3-6 Surgical management of OHVIRA syndrome

Tomoko Nagata, Takeshima Kazumi, Yoshiyuki Nomura, Hideya Sakakibara, Fumiki Hirahara
Department of Obstetrics and Gynecology, Yokohama City University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S599-S599, 2010.

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P11-3-7 A case of SRY-positive, 46,XX/45,X/47,XXX DSD identified in the eighth decade of life

Takeshi Nigawara, Maki Yamashita, Shinobu Takayasu, Hiroshi Murakami, Toshihiro Suda
Department of Endocrinology and Metabolism, Hirosaki University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S599-S599, 2010.

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P11-3-8 Topical treatment of pueraria mirifica extract on vaginal atrophy in ovariectomized rats and menopausal monkeys

Sukanya Jaroenporn(1), Nontakorn Urasopon(2), Suchinda Malaivijitnond(1)
(1)Primate Research Unit, Department of Biology, Faculty of Science, Chulalongkorn University, (2)Department of Animal Science, Faculty of Agriculture, Ubon Ratchathani University
ENDOCRINE JOURNAL 57 (suppl.2-2) S599-S599, 2010.

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P11-4-1 Observation of the morphological change on sperm in the rat administrated Dibromochloropropane by utilizing dark field images in the computer-assisted sperm analysis

Katsumi Ohtani(1), Shigeru Yamazaki(2)
(1)Hazard Evaluation and Epidemiology Research Group, (2)School of Medicine, Sowa University
ENDOCRINE JOURNAL 57 (suppl.2-2) S599-S599, 2010.

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P11-4-2 Effects of nanoparticle-rich diesel exhaust on adrenal and testicular steroid secretion in male mice

Xuezheng Li(1), ChunMei Li(2), Lingmei Pan(1), (3), Junko Jigami(1), Wen Cao(1), Akira K.Suzuki(4), Gen Watanabe(1), (3), Tamie Nakajima(5), Kazuyoshi Taya(1), (3)
(1)Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, (2)College of Animal Science and Technology, Nanjing Agricultural University, (3)Department of Basic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, (4)Research Center for Environmental Risk, National Institute for Environmental Studies, (5)Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S600-S600, 2010.

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P11-4-3 Expression of TPR domain containing NYD-SP14 gene in the maturing rat testis

Masanori Ohta(1), Kouji Kobayashi(1), Kazumasa Sato(1), Mie Mochizuki(1), Yumiko Mitsui(1), Kenjiro Nagamine(1), Hideaki Yagasaki(1), Yoshiaki Yamano(2), Kenji Ohyama(1)
(1)Department of Pediatrics, University of Yamanashi, (2)Laboratory of Veterinary Biochemistry, Faculty of Agriculture, Tottori University
ENDOCRINE JOURNAL 57 (suppl.2-2) S600-S600, 2010.

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P11-4-4 Reproductive problems and urinary dosage of phthalates:Pilot study in couples within a center for assisted fertilization

Alessandra Pera(1), Lidia Caporossi(1), Cesare Aragona(2), Giovanna Tranfo(1), Enrico Paci(1), Mariangela De Rosa(1), Silvia Capanna(1), Laura Marcellini(1), Stefano Galli(1), Bruno Papaleo(1)
(1)Department of Occupational Medicine, ISPESL-National Institute of Occupational Safety and Prevention, (2)Polyclinic Umberto I, University of Rome La Sapienza
ENDOCRINE JOURNAL 57 (suppl.2-2) S600-S600, 2010.

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P11-4-5 Morpho-functional studies on the male gonad:correlations of circulating hormones with testicular volume and echo-texture

Daniele Gianfrilli, Rosaria Chiossi, Carlotta Pozza, Elisa Giannetta, Simona Granato, Antonella Anzuini, Donatella Paoli, Loredana Gandini, Antonio Radicioni, Andrea Lenzi, Andrea M.Isidori
Department of Medical Physiopathology, Sapienza University of Rome
ENDOCRINE JOURNAL 57 (suppl.2-2) S600-S600, 2010.

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P11-4-6 Semen parameters and male subfertility:Retrospective analysis of 453 pregnancies

Domenico Milardi(1), Giuseppe Grande(2), Antonio Bianchi(2), Antonella Giampietro(1), Anna Maria Merola(1), Anna Laura Astorri(1), Giuseppina Pompa(1), Alfredo Pontecorvi(2), Laura De Marinis(2), Riccardo Marana(1)
(1)Department of Gynecology and Obstetrics, International Scientific Institute Paolo VI, Catholic University, School of Medicine, (2)Department of Endocrinology, Catholic University, School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S601-S601, 2010.

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P11-4-7 Subclinical hypothyroidism as ethiological factor of female infertility

Antonella Giampietro(1), Giuseppe Grande(2), Domenico Milardi(1), Anna Laura Astorri(1), Giuseppina Pompa(1), Anna Maria Merola(1), (2), Alfredo Pontecorvi(1), Antonio Lanzone(1), Riccardo Marana(1), Laura De Marinis(2)
(1)Department of Gynecology and Obstetrics, International Scientific Institute Paolo VI, Catholic University, School of Medicine, (2)Department of Endocrinology; Catholic University
ENDOCRINE JOURNAL 57 (suppl.2-2) S601-S601, 2010.

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P11-4-8 Congruent-consensus guidelines for the rational use of nutraceuticals in male subfertility

Sanjay Kalra(1), Phagun Shah(2), Ajit Saxena(3), Navneet Agrawal(4)
(1)Bharti Hospital, (2)Ahmedabad, (3)New Delhi, (4)Gwalior
ENDOCRINE JOURNAL 57 (suppl.2-2) S601-S601, 2010.

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P11-5-1 Regulation of prostaglandin F2α receptor(FP)mRNA in human decidua cells during pregnancy and parturition

Shintaro Makino(1), (2), Kikumi Matsuoka(2), Aman Aidiresi(1), (2), Hiroyuki Seki(2), Satoru Takeda(1), David Olson(3)
(1)Deapartment of Obstetrics and Gynecology, Juntendo University of Medicine, (2)Deapartment of Obstetrics and Gynecology, Saitama Medical Center, (3)Perinatal Research Centre, University of Alberta
ENDOCRINE JOURNAL 57 (suppl.2-2) S601-S602, 2010.

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P11-5-2 Stimulation of angiogenesis by prostaglandin e2 in luteal endothelial cells

Kazuhiro Tamura, Eiichi Tachikawa
Depart of Endocrine Pharmacology, Tokyo University of Pharmacy Life Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S602-S602, 2010.

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P11-5-3 Placental glucocorticoid metabolism is modulated by antioxidant system and affects pancreatic function of the offspring in later life

Takashi Umekawa, Takashi Sugiyama, Lingyun Zhang, Nao Murabayashi, Norimasa Sagawa
Department of Obstetrics and Gynecology, Mie University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S602-S602, 2010.

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P11-5-4 Neonatal immune challenge affects the regulation of estrus cycle and feeding behavior in female rats

Takeshi Iwasa, Toshiya Matsuzaki, Riyo Kinouchi, Ganbat Gereltsetseg, Minoru Irahara
Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School
ENDOCRINE JOURNAL 57 (suppl.2-2) S602-S602, 2010.

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P11-5-5 Changes in body weight during the first year of life y its relationship with breast feeding and leptin levels the first week of life

J Manuel Malacara, Lorena Ibarra
Department of Medical Science, Div.Of Health Science, Campus Leon, University of Guanajuato
ENDOCRINE JOURNAL 57 (suppl.2-2) S602-S602, 2010.

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P11-5-6 Differences between maternal and fetal steroids indicate that the placental distribution of the reductase-or oxidoreductase-preferring isoforms is decisive for different biological activity of gestagens estrogens and neuroactive steroids in mother and fetus

Martin Hill(1), Antonin Parizek(2), Jan E Jirasek(3), Radmila Kanceva (1), Luboslav Starka(1)
(1)Instiiute of Endocrinology, (2)Department of Obstetrics and Gynecology of the First Faculty of Medicine and General Turning Hospital, (3)Institute for The Care of Mother and Child
ENDOCRINE JOURNAL 57 (suppl.2-2) S603-S603, 2010.

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P11-5-7 Relationships between various forms of maternal and fetal estrogens and gestagens demonstrate that the placental distribution of the reductase-or oxidoreductase-preferring isoforms is decisive for the reductive status of steroid metabolome in mother and the oxidative one in the fetus

Radmila Kanceva(1), Martin Hill(1), Antonin Parizek(2), Jan E Jirasek(3), Luboslav Starka(1)
(1)Institute of Endocrinology, (2)Department of Obstetrics and Gynecology of the First Faculty of Medicine and General Teaching Hospital, (3)Institute for the Care of Mother and Child
ENDOCRINE JOURNAL 57 (suppl.2-2) S603-S603, 2010.

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P11-5-8 Neonatal lipopolysaccharide exposure attenuates the suppressive responses of LH secretion to homotypic immune challenge in adulthood in male rat

Toshiya Matsuzaki, Takeshi Iwsa, Riyo Kinouchi, Ganbat Gereltsetseg, Minoru Irahara
Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School
ENDOCRINE JOURNAL 57 (suppl.2-2) S603-S603, 2010.

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P11-6-1 Effect of acute stress on cortisol content in embryo and larvae of rainbow trout

Amir P.Salati(1), Gholamreza Ghaedi(1), Vahid Yavari(1), Bahram Falahatkar(2), Einalah Gorjipour(3)
(1)Department of Fisheries, Faculty of Natural Resources, Khoramshahr Marine Science and Technology University, (2)Department of Fisheries, Faculty of Marine Natural Resources, Univrsity of Gilan, (3)Iranian fisheries research organization
ENDOCRINE JOURNAL 57 (suppl.2-2) S603-S604, 2010.

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P11-6-2 Identification and functional analysis of novel human growth hormone secretagogue receptor type 1a variants in Japanese subjects with short stature

Hiroshi Inoue(1), Yukiko Sakamoto(1), Mitsuo Itakura(1), (4), Tsutomu Ogata(2), (4), Kenji Fujieda(3), (4), Growth Genome Consortium(4)
(1)Division of Genetic Information, Institute for Genome Research, The University of Tokushima, (2)Department of Endocrinology and Metabolism, National Research Institute for Child Health and Development, (3)Department of Pediatrics, Asahikawa Medical College, (4)Growth Genome Consortium
ENDOCRINE JOURNAL 57 (suppl.2-2) S604-S604, 2010.

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P11-6-3 IGFBP-3 replacement mitigates GnRH-A induced male germ cell apoptosis in IGFBP-3 KO mice:New insights into regulation of germ cell programmed cell death

Christina Wang(1), Yue Jia(1), Hemal H.Mehta(2), Kuk-wha Lee(2), Laura J.Cobb(2), Yan-he Lue(1), Vince Atienza(1), Pincus Cohen(2), Ronald S.Swerdloff(1)
(1)Division of Endocrinology, Department of Medicine, Harbor-UCLA Medical Center and Los Angeles Biomedical Research Institute, (2)Division of Pediatric Endocrinology, Department of Pediatric, Mattel Children Hospital and David Geffen School of Medicine at UCLA
ENDOCRINE JOURNAL 57 (suppl.2-2) S604-S604, 2010.

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P11-6-4 Compound heterozygous mutations of a gene for tachykinin receptor 3 in a Japanese female with isolated hypogonadotropic hypogonadism

Maki Fukami(1), Tetsuo Maruyama(2), Sumito Dateki(1), Naoko Sato(1), Yasunori Yoshimura(2), Tsutomu Ogata(1)
(1)Department of Endocrinology and Metabolism, Natural Research Institute for Child Health and Development, (2)Department of Obstetrics and Gynecology, Keio University school of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S604-S604, 2010.

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P11-6-5 Palmitate regulates GnRH receptor mRNA expression levels in the gonadotrope of the mouse anterior-pituitary gland

Chikaya Deura(1), (2), Nobuyuki Fukushima(1), (3), Ryutaro Moriyama(1)
(1)Department of Life Science, Kinki University, (2)Graduate School of Science and Technology, Kinki University, (3)Research Institute for Science and Technology, Kinki University
ENDOCRINE JOURNAL 57 (suppl.2-2) S604-S605, 2010.

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P11-6-6 Mechanisms of insulin receptor and GnRH receptor signaling interaction in gonadotropes

Emily L.Rickert, Amy M.Navratil, Hyunjin Song, Mark A.Lawson
The Department of Reproductive Medicine, University of California San Diego
ENDOCRINE JOURNAL 57 (suppl.2-2) S605-S605, 2010.

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P11-6-7 Bone morphogenetic proteins regulate GnRH production by GT1-7 hypothalamic cells

Hiroyuki Otani(1), Fumio Otsuka(1), Masaya Takeda(1), Tomoko Miyoshi(1), Kenichi Inagaki(1), Jiro Suzuki(1), Naoko Tsukamoto(1), Eri Nakamura(1), Mark A.Lawson(2), Hirofumi Makino(1)
(1)Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, (2)Department of Reproductive Medicine, University of California
ENDOCRINE JOURNAL 57 (suppl.2-2) S605-S605, 2010.

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P11-6-8 2-deoxy-D-glucose(2DG)induced glucoprivation suppressed gonadotropin-releasing hormone receptor(GnRH-R)and follicular stimulating hormone a subunit(FSHβ)mRNA expression levels in the LβT2 gonadotroph cells

Ryutaro Moriyama(1), Ai Nakai(1), Nobuyuki Fukushima(2)
(1)Department of Life Science, Kinki University, (2)Research Institute for Science and Technology
ENDOCRINE JOURNAL 57 (suppl.2-2) S605-S605, 2010.

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P11-7-1 Polyclonal origin of endocrine organs and individual hormone producing cell population evaluated as direct in situ demonstration in EGFP/BALB/C chimeric mice

Defu Ma(1), Katsuko Sudo(2), Hideo Tezuka(3), Tetsuo Kondo(1), Dongfeng Niu(1), Tadao Nakazawa(1), Tomonori Kawasaki(1), Kunio Mochizuki(1), Tetsu Yamane(1), Ryohei Katoh(1)
(1)Department of Pathology, University of Yamanashi, (2)Tokyo Medical University Animal Research Center, (3)Center for Life Science Research, University of Yamanashi
ENDOCRINE JOURNAL 57 (suppl.2-2) S605-S606, 2010.

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P11-7-2 Hedgehog signaling in the rat testis

Jorma Toppari(1), Juho-Antti Makela(1), Sonia Bourguiba(1), Vuokko Saario(1), Sami Ventela(2), Mirja Nurmio(1), Martti Parvinen(1)
(1)Departments of Physiology and Pediatrics, University of Turku, (2)Department of Oto-Rhino-Laryngology, Turku University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S606-S606, 2010.

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P11-7-3 Role of the activin signaling during islet morphogenesis

Akemi Hara(1), Satoko Yamada(1), Yoritsuna Yamamoto(2), Tsutomu Kodera(2), Kohei Hamamoto(1), Rie Yoshida(2), Itaru Kojima(1)
(1)Department of Cell Physiology, Institute for Molecular and Cellular Regulation, Gunma University, (2)Third Department of Internal Medicine, National Defense Medical College
ENDOCRINE JOURNAL 57 (suppl.2-2) S606-S606, 2010.

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P11-7-4 Nerve growth factor, tyrosine hydroxylase and apoptotic regulators in the testis of socially isolated mice:modulation by low-frequency electro-acupuncture.

Luigi Manni(1), Marco Fiore(1), Giovanna Franconi(2), Andrea Fabbri(2), Luigi Aloe(1)
(1)Institute of Neurobiology and Molecular Medicine, CNR, (2)Endocrinology Unit, Department of Internal Medicine, Tor Vergata University
ENDOCRINE JOURNAL 57 (suppl.2-2) S606-S606, 2010.

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P11-7-5 A novel transcriptional corepressor, SNASH regulates maintenance of neuronal stem cell differentiation

Ken-ichi Takeyama(1), Saya Ito(1), (2), Shun Sawatsubashi(1), (2), Alexander Kouzmenko(1), (2), Eriko Suzuki(1), Masahiko Tanabe(1), (2), Sally Fujiyama(1), (2), Fumiaki Ohtake(1), Yukiko Gotoh(1), Shigeaki Kato(1), (2)
(1)Institute of Molecular and Cellular Biosciences, University of Tokyo, (2)ERATO, Japan Science and Technology Agency
ENDOCRINE JOURNAL 57 (suppl.2-2) S606-S607, 2010.

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P11-7-6 Bone marrow angiotensin AT1 receptor regulates differentiation of monocyte lineage progenitors from hematopoietic stem cells

Hiroyuki Yamada(1), Yoshinori Tsubakimoto(1), Hirokazu Yokoi(1), Sou Kishida(1), Taku Kato(1), Hiroyuki Kawahito(1), Hideyo Hirai(2), Eishi Asihara(2), Taira Maekawa(2), Kouji Ikeda(1), Tomosaburo Takahashi(1), Mitsuhiko Okigaki(1), Hiroaki Matsubara(1)
(1)Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine, (2)Department of Transfusion Medicine and Cell Therapy, Kyoto University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S607-S607, 2010.

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P11-7-7 Bone marrow All augments neointima formation by promoting mobilization of smooth muscle progenitorsvia platelet-derived SDF-1α

Hiroyuki Yamada(1), Hirokazu Yokoi(1), Yoshinori Tsubakimoto(1), Hiroyuki Kawahito(1), Sou Kishida(1), Taku Kato(1), Hideyo Hirai(2), Eishi Asihara(2), Taira Maekawa(2), Masaru Iwai(3), Masatsugu Horiuchi(3), Kouji Ikeda(1), Tomosaburo Takahashi(1), Mitsuhiko Okigaki(1), Hiroaki Matsubara(1)
(1)Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine, (2)Department of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, (3)Department of Molecular Cardiovascular Biology and Phamacology, Ehime University Graduate School of Meicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S607-S607, 2010.

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P11-7-8 Hydroxysteroid(17beta)dehydrogenase 7 knockout mice present with defects in fetal de novo cholesterol synthesis, neuroectodermal survival and cardiovascular differentiation

Matti Poutanen(1), Heli Heli Jokela(1), Pia Rantakari(1), Tarja Lamminen(1), Leena Strauss(1), Roxana Ola(2), Helena Gylling(3), Tatu Miettinen(4), Pirjo Pakarinen(1), Kirsi Sainio(2)
(1)Department of Physiology, Institute of Biomedicine, University of Turku, (2)Department of Medical Biochemistry and Developmental Biology, Institute of Biomedicine, University of Helsinki, (3)Department of Clinical Nutrition and Department of Medicine, University of Kuopio, (4)Department of Medicine, Institute of Internal Medicine, University of Helsinki, (5)Department of Medical Biochemistry and Developmental Biology, Institute of Biomedicine, University of Helsinki
ENDOCRINE JOURNAL 57 (suppl.2-2) S607-S607, 2010.

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P11-7-9 Hydroxysteroid(17beta)dehydrogenase 12 is essential for mouse organogenesis and embryonic survival

Matti Poutanen(1), Pia Rantakari(1), Heli Lagerbohm(1), Mika Kaimainen(2), Jukka-Pekka Suomela(2), Leena Strauss(1), Kirsi Sainio(3), Pirjo Pakarinen(1)
(1)Department of Physiology, Institute of Biomedicine, University of Turku, (2)Department of Biochemistry and Food Chemistry, University of Turku, (3)Department of Medical Biochemistry and Developmental Biology, Institute of Biomedicine, University of Helsinki
ENDOCRINE JOURNAL 57 (suppl.2-2) S607-S608, 2010.

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P11-8-1 Endocrine diseases among women patients with indefinite coomplaints:analysis at department of gender medicine

Miyuki Katai(1), (2), Jinko Yokota(1), (2), Toshiko Kamo(1), (2), Miwako Kawamata(1), Noriko Oi(1), (2), Mariko Kusuyama(1), (2), Rieko Yamada(1), Kumiko Taira(1), Yasuko Arai(1), Naoko Kikuchi(1), Mieko Sato(1), Motoko Miyako(1), Wookyung Kim(3), Toshihito Saitoh(4), Kuniaki Otsuka(4)
(1)Department of Gender Medicine, Medical Center East, Tokyo Women's Medical University, (2)Institute of Women's Health, Tokyo Women's Medical University, (3)Nagasaki University School of Medicine, (4)Department of Internal Medicine, Medical Center East, Tokyo Women's Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S608-S608, 2010.

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P11-8-2 Epidemiology of menstrual disorders and diseases of mammary glands in adolescent girls

Olga I.Gumenyuk, Yuri V.Chernenkov
Saratov Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S608-S608, 2010.

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P11-8-3 Causing trouble:The need for medically assisted conception is a marker for metabolic complications of pregnancy, especially in obese women

Mark McLean(1), Philomena Henriksson(2), Jennifer Bradford(2)
(1)School of Medicine, University of Western Sydney, (2)Blacktown Hospital, Antenatal Service
ENDOCRINE JOURNAL 57 (suppl.2-2) S608-S608, 2010.

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P11-8-4 The relationship between obesity, insulin resistance and dyslipidemia in romanian polycystic ovary syndrome patients

Simona V.Fica(1), Alice I.Albu(2), Madalina I.Constantin(2), Serban Radian(1), Florin Grigorescu(3), Suzana Florea(2)
(1)Department of Endocrinology, UMF Carol Davila, (2)Elias Hospital, Endocrinology Department, (3)Molecular Endocrinology Laboratory, IURC Montpellier
ENDOCRINE JOURNAL 57 (suppl.2-2) S608-S609, 2010.

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P11-8-5 Diet-induced obesity disrupts postnatal and pregnancy-induced mammary gland development in mice:Possible roles of leptin

Akihiro Kamikawa, Chiharu Suzuki, Atsuko Yamamoto, Yuko Okamatsu, Akira Terao, Kazuhiro Kimura
Laboratory of Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University
ENDOCRINE JOURNAL 57 (suppl.2-2) S609-S609, 2010.

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P11-8-6 How metabolic hormones ghrelin, leptin and obestatin control ovarian functions

Alexander Sirotkin
Animal Production Research Centre Nitra
ENDOCRINE JOURNAL 57 (suppl.2-2) S609-S609, 2010.

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P11-8-7 Effect of menopausal hormone therapy on osteoarthritis pain in peri-and postmenopausal women

David C.Miller(1), Lovera W.Miller(1), Sasha M.Franger(1), Brienna G.Miller(2)
(1)Woodland Pain Center, (2)health 4 her
ENDOCRINE JOURNAL 57 (suppl.2-2) S609-S609, 2010.

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P11-8-8 Insulin resistance is associated with oligomenorrhea in premenopausal women

Unjin Shim, Hyejin Lee, Jee-Young Oh, Young Sun Hong, Yeon-Ah Sung
Division of Endocrinology, Department of Internal Medicine, Ewha Womans University College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S609-S610, 2010.

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P11-8-9 Cause of primary amenorrhea in a Filipina:The Mayer-Rokitansky-Kuster-Hauser syndrome(mullerian agenesis, congenital absence of the uterus and vagina)

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P11-9-1 Multiple protective effects of locally administered inhibitors of group IVA phospholipase A2 and cyclooxygenase-2 on pseudopregnant rat corpus luteum from prostaglandin F2a-induced regression

Shiro Kurusu, Norifumi Sonoda, Masato Nakahara, Tomohiro Yonezawa, Mitsumori Kawaminami
Veterinary Physiology, Kitasato University School of Veterinary Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S610-S610, 2010.

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P11-9-2 Absence of the secondary FSH surge in female horses-A new feedback system via abdominal cavity in the regulation of FSH secretion in female horses-

Yasuo Nambo(1), (2), Gen Watanabe(2), (3), Kazuyoshi Taya(2), (3)
(1)Equine Science Division, Hidaka Training and Research Center, Japan Racing Association, (2)Department of Basic Veterinary Science, The United Graduate School of Veterinary Sciences Gifu University, (3)Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology
ENDOCRINE JOURNAL 57 (suppl.2-2) S610-S610, 2010.

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P11-9-3 Changes in circulating follicle stimulating hormone(FSH), luteinizing hormone(LH), immunoreactive(IR)inhibin, prolactin, progesterone, testosterone and estradiol-17β in thoroughbred colts and fillies from birth to 63 weeks of age

Pramod Dhakal(1), (2), Akio Otsuka(2), Yasuo Nambo(3), Nobuo Tsunoda(4), Hiroyuki Taniyama(5), Gen Watanabe(1), (2), Kazuyoshi Taya(1), (2)
(1)Department of Basic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, (2)Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture Tokyo University of Agriculture and Technology, (3)Equine Science Division, Hidaka Training and Research Center, Japan Racing Association, (4)Shadai Corporation, (5)Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University
ENDOCRINE JOURNAL 57 (suppl.2-2) S610-S611, 2010.

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P11-9-4 Special characteristic of a luteinizing hormone surge in captive male African elephant(Loxodonta africana)

Saroch Kaewmanee(1), (2), Gen Watanabe(1), (2), Megumi Keio(2), Natsuki Yuto(2), Tatsuya Yamamoto(1), (2), Yuki Yamamoto(1), (2), Etsuo Narushima(3), Masayuki Katayanagi(3), Risa Nakao(3), Yuko Sakurai(3), Shu Morikubo(3), Mikako Kaneko(3), Kazuyoshi Taya(1), (2)
(1)Department of Basic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, (2)Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, (3)Tama Zoological Park
ENDOCRINE JOURNAL 57 (suppl.2-2) S611-S611, 2010.

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P11-9-5 Effect of Insulin like growth factor-1 in a semi-defined culture medium on bovine embryo developmental competence in normal and heat stress conditions

Mahdi Zhandi(1), Armin Towhidi(2), Mohammad Hossein Nasr-Esfahani(3), Poopak Eftekhari-Yazdi(4), Ahmad Zare Shahne(5)
(1)Department of Animal Science, Faculty of Agronomy and Animal Science, University of Tehran, (2)University Tehran, (3)Royan Institute, (4)Royan Institute, (5)University Tehran
ENDOCRINE JOURNAL 57 (suppl.2-2) S611-S611, 2010.

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P11-9-6 Effects of fish oil dietary as a source of n-3 fatty acids on reproduction parameters of Iranian Holstein bull

Ali Khoshvaght(2), Armin Towhidi(1), Ahmad Zare Shahne(1), Mohammad Nourozi(2), Abasali Naserian(3)
(1)Department of Animal Science, Faculty of agricultural of Science and Engineering, University of Tehran, (2)Department of Animal Science, Agricultural and Natural Resources Research Center, Khorasan Province, (3)Department of Animal Science, Ferdowsi University of Mashhad
ENDOCRINE JOURNAL 57 (suppl.2-2) S611-S611, 2010.

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P11-9-7 Regulatory mechanism(s)of ovarian stem cell proliferation in fish(Danio rerio)and frog(Euphlyctis cyanophlyctis)ovary

Prasad A.Deshpande, Pancharatna A.Katti
Department of Zoology, Karnatak University
ENDOCRINE JOURNAL 57 (suppl.2-2) S611-S611, 2010.

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P11-9-8 EDC(Acephate)induced developmental deformities in Bufo melanostictus

Manjunath G.Ghodageri, Pancharatna A.Katti
Department of Zoology, Karnatak University
ENDOCRINE JOURNAL 57 (suppl.2-2) S612-S612, 2010.

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P11-9-9 Modulatory role of versons glands peptide in insect metamorphosis

Muraleedharan Damodaran, Gayathri E.Uma, R.V.Omkumar, Vasudevanpillai Biju, Govindan Bhaskaran
Center for Arthropod Bioresources and Biotechnology, University of Kerala
ENDOCRINE JOURNAL 57 (suppl.2-2) S612-S612, 2010.

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P11-10-1 PGC-1alpha regulates progesterone production in ovarian granulosa cells with SF-1 and LRH-1

Takashi Yazawa, Kaoru Miyamoto
Department of Biochemistry, Faculty of Medical Sciences, University of Fukui
ENDOCRINE JOURNAL 57 (suppl.2-2) S612-S612, 2010.

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P11-10-2 Effect of oncostatin M on uridine diphosphate-5-glucuronosyltransferase 1A1 through crosstalk with constitutive androstane receptor

Hisashi Masuyama, Hideki Nakatsukasa, Yuji Hiramatsu
Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Silences
ENDOCRINE JOURNAL 57 (suppl.2-2) S612-S612, 2010.

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P11-10-3 Effects of tumor necrosis factor-alpha on activin a production in human amniotic epithelial cells

Yumiko Abe(1), Maki Komatsubara(2), Megumi Saito(2), Mayuho Toda(2), Nami Tsuru(2), Risa Marukawa(2), Erika Oohata(1), Chikaru Suzuki(1), Nori Terada(1), Hiromitsu Shinozaki(3), Yoshimitsu Kasahara(4), Tomohiro Tamura(4), Hisanobu Sadakata(4), Yusuke Katsumata(4), Takashi Minegishi(4)
(1)Department of Laboratory Sciences, School of Health Sciences, Faculty of Medicine, Gunma University, (2)Department of Laboratory Science and Environmental Health Science, Gunma University Graduate School of Medicine, (3)Department of Nursing, School of Health Sciences, Faculty of Medicine, Gunma University, (4)Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S612-S613, 2010.

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P11-10-4 Protective effect of quercetin on the reproductive toxicity of 4-nitrophenol in diesel exhaust particles on male embryonic chickens

Yuling Mi(5), Caiqiao Zhang(2), ChunMei Li(4), Shinji Taneda(3), Gen Watanabe(1), (5), Akira K Suzuki(3), Kazuyoshi Taya(1), (5)
(1)Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, (2)Key Laboratory of Animal Epidemic Etiology & Immunological Prevention of the Ministry of Agriculture, College of Animal Sciences, Zhejiang University, (3)Environmental Nanotoxicology Section, Research Center for Environmental Risk, National Institute for Environmental Studies, (4)Laboratory of Animal Reproduction, College of Animal Science and Technology, Nanjing Agricultural University, (5)Department of Basic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University
ENDOCRINE JOURNAL 57 (suppl.2-2) S613-S613, 2010.

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P11-10-5 Molecular mechaniam of isocupressic acid(IA)suppress MA-10 cell steroidogenesis

Jyun-Yuan Wang, Meng-Chien Hsu, Yi-Fan Jiang, Chia-Li Shih, Chih-Hsien Chiu
Department of Animal Science and Technology, National Taiwan University
ENDOCRINE JOURNAL 57 (suppl.2-2) S613-S613, 2010.

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P11-10-6 The functional Kisspeptin-GPR54 regulatory system in mouse testis

Meng-Chieh Hsu, Tai-Hsiang Tseng, Yi-Fan Jiang, Jyun-Yuan Wang, De-Shien Jong, Leang-Shin Wu, Chih-Hsien Chiu
Department of Animal Science and Technology, National Taiwan University
ENDOCRINE JOURNAL 57 (suppl.2-2) S613-S613, 2010.

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P11-10-7 Effects of fibroblast growth factor(FGF)-8 on ovarian steroidogenesis:involvement of upregulation of BMP receptor singnaling

Tomoko Miyoshi, Fumio Otsuka, Misuzu Yamashita, Kenichi Inagaki, Jiro Suzuki, Eri Nakamura, Naoko Tsukamoto, Masaya Takeda, Yukari Mimura, Toshio Ogura, Hirofumi Makino
Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S613-S614, 2010.

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P11-10-8 Improved superovulation induction in A/J mice based on the luteinizing hormone receptor protein expression pattern

Osamu Suzuki, Minako Koura, Yoko Noguchi, Kozue Uchio-Yamada, Junichiro Matsuda
Laboratory of Experimental Animal Models, National Institute of Biomedical Innovation
ENDOCRINE JOURNAL 57 (suppl.2-2) S614-S614, 2010.

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P11-10-9 Identification of a novel factor required for spermatogenesis by an in vivo tesits luciferase assay(t-Luc)screen

Shuhei Kimura(1), (2), Saya Ito(1), Shun Sawatsubashi(1), Eriko Suzuki(1), Masahiko Tanabe(1), Takashi Ueda(1), Takuya Murata(1), Sally Fujiyama(1), Hiroyuki Matsukawa(1), Jinseon Lim(1), Ken-ichi Takeyama(1), Shigeaki Kato(1)
(1)The Institute of Molecular and Cellular Biosciences, University of Tokyo, (2)Research Fellow of the Japan Society for the Promotion of Science
ENDOCRINE JOURNAL 57 (suppl.2-2) S614-S614, 2010.

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P12-1-1 Physiological roles of the Hes1 in the pancreas

Junji Fujikura(1), Masaki Naito(1), Kiminori Hosoda(1), Hiroshi Iwakura(1), Tsutomu Tomita(1), Michio Noguchi(1), Shinji Odori(1), Eisaku Mori(1), Chisako Kozuka(1), Yuji Yamamoto(1), Ken Ebihara(1), Hiroaki Masuzaki(1), Yoshiya Kawaguchi(2), Rhoichiro Kageyama(3), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Surgery and Surgical Basic Science, Kyoto University Graduate School of Medicine, (3)Institute for Virus Research, Kyoto University
ENDOCRINE JOURNAL 57 (suppl.2-2) S614-S614, 2010.

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P12-1-2 Induction of vascular cells and adipocytes from human induced pluripotent stem cells

Daisuke Taura(1), Masakatsu Sone(1), Koichiro Homma(2), Naohisa Tamura(1), Yasutomo Fukunaga(1), Megumi Inuzuka(1), Takuhiro Sonoyama(1), Kyoko Honda(1), Katsutoshi Kojima(1), Hiroshi Arai(1), Kazuwa Nakao(1)
(1)The Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Department of Internal Medicine, Keio University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S614-S614, 2010.

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P12-1-3 The characteristic and potential of human ES and iPS-derived vascular cells

Masakatsu Sone, Koichiro Homma, Daisuke Taura, Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S615-S615, 2010.

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P12-1-4 Cardiomyocytes differentiation from human ESCs and human iPSCs

Masataka Fujiwara(1), (2), Peishi Yan(3), Tomomi G.Otsuji(4), Narazaki Genta(2), Hideki Uosaki(2), Hiroyuki Fukushima(2), Hiroyuki Matsuda(5), Satoshi Matsuoka(5), Kazutoshi Takahashi(6), (7), Kazuwa Nakao(1), Norio Nakatsuji(8), (9), Shinya Yamanaka(6), (7), (9), (10), Jun K.Yamashita(2), (7)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University, (3)Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, (4)Stem Cell and Drug Discovery Institute, (5)Department of Physiology and Biophysics, Kyoto University Graduate School of Medicine, (6)Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, (7)Center for iPS Cell Research and Application, Institute for Integrated Cell-Material Sciences, Kyoto University, (8)Department of Development and Differentiation, Institute for Frontier Medical Sciences, Kyoto University, (9)Institute for Integrated Cell-Material Sciences, Kyoto University, (10)CREST, Japan Silence and Technology Agency
ENDOCRINE JOURNAL 57 (suppl.2-2) S615-S615, 2010.

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P12-1-5 The role of Sfrp1 or Inhbb during SF-1-mediated steroidogenic cell differentiation of bone marrow stromal cells

Tomoko Tanaka, Toshihiko Yanase
Department of Endocrinology and Diabetes Mellitus of School of Medicine, Fukuoka University
ENDOCRINE JOURNAL 57 (suppl.2-2) S615-S615, 2010.

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P12-1-6 Pathological role of angiostatin in heart failure:An endogenous inhibitor of mesenchymal stem cell activation

Kenichi Yamahara(1), Kyung Duck Min(2), HitonobuTomoike Tomoike(2), Kenji Kangawa(3), Kitamura Kitamura(4), Noritoshi Nagaya(1)
(1)Department of Regenerative Medicine and Tissue Engineering, National Cardiovascular Center Research Institute, (2)Department of Cardiovascular Medicine, National Cardiovascular Center, (3)Department of Biochemistry, National Cardiovascular Center Research Institute, (4)Department of Cardiovascular Surgery, National Cardiovascular Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S615-S615, 2010.

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P12-1-7 Transplanted allogenic fetal membrane-derived mesenchymal stem cell contributes to renal repair via paracrine actions in experimental glomerulonephritis

Hidetoshi Tsuda(1), (2), Kenichi Yamahara(1), Shin Ishikane(1), Kentaro Otani(1), Masaharu Sada(1), Masaru Horio(2), Yoshitaka Isaka(2), Shiro Takahara(2), Kenji Kangawa(1), Tomoaki Ikeda(1)
(1)National Cardiovascular Center Research Institute, (2)Osaka University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S616-S616, 2010.

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P12-1-8 Carbamylated erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney

Yoshitaka Isaka(1), Ryoichi Imamura(2), Shiro Takahara(2), Bruce A Molitoris(3), Hiromi Rakugi(1)
(1)Departments of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, (2)Departments of Advanced Technology for Transplantation, Osaka University Graduate School of Medicine, (3)Department of Nephrology, Indiana University
ENDOCRINE JOURNAL 57 (suppl.2-2) S616-S616, 2010.

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P12-1-9 Allogeneic transplantation of fetal membrane derived-mesenchymal stem cells induces therapeutic angiogenesis through paracrine manner

Shin Ishikane(1), (2), (3), Kenichi Yamahara(1), Kazuhiko Harada(4), Kenichi Mishima(3), Katsunori Iwasaki(3), Michihiro Fujiwara(3), Kenji Kangawa(4), Tomoaki Ikeda(1), (2)
(1)Department of Regenerative Medicine & Tissue Engineering, National Cardiovascular Center Research Institute, (2)Department of Perinatology, National Cardiovascular Center, (3)Department of Neuropharmacology, Faculty of Pharmaceutical Science, Fukuoka University, (4)Department of Biochemistry, National Cardiovascular Center Research Institute
ENDOCRINE JOURNAL 57 (suppl.2-2) S616-S616, 2010.

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P13-1-1 A novel mutation in the seventh transmembrane segment of the LHCGR gene in Japanese boy with peripheral precocious puberty

Keisuke Nagasaki(1), Noriyuki Katsumata(2), Yohei Ogawa(1), Toru Kikuchi(1)
(1)Department of Pediatrics, Niigata University, (2)Department of Endocrinology and Metabolism, National Research Institute for Child Health and Development
ENDOCRINE JOURNAL 57 (suppl.2-2) S616-S617, 2010.

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P13-1-2 Hierarchical interaction and distinct functional properties of the IG-DMR and the MEG3-DMR at the human chromosome 14q32.2 imprinted region

Masayo Kagami(1), Maureen J.O'Sullivan(2), Andrew J.Green(3), Yoshiyuki Watabe(4), Osamu Arisaka(4), Toshiro Nagai(5), Shuji Takada(6), Maki Fukami(1), Kazuki Yamazawa(1), Keiko Matsubara(1), Fumiko Kato(1), Anne C.Ferguson-Smith(7), Tsutomu Ogata(1)
(1)Department of Endocrinology and Metabolism, National Research Institute for Child Health and Development, (2)Department of Pathology, Our Lady's Children's Hospital, and School of Medicine, Trinity College, (3)National Center for Medical Genetics, University College Dublin, Our Lady's Hospital, and School of Medicine and Medical Silence, University College, (4)Department of Pediatrics, Dokkyo University School of Medicine, (5)Department of Pediatrics, Dokkyo University School of Medicine Koshigaya Hospital, (6)Department of Innovative Surgery, National Research Institute for Child Health and Development, (7)Department of Physiology, Development and Neuroscience, University of Cambridge
ENDOCRINE JOURNAL 57 (suppl.2-2) S617-S617, 2010.

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P13-1-3 The usefulness of Matsuda Index for disposition indices in the follow-up of SGA children treated with GH

Koji Kobayashi(1), (5), Shin Amemiya(2), Keiji Kobayashi(3), Masaya Hoshino(2), Tomohiro Saito(1), Junya Akatsuka(2), Kisho Kobayashi(1), Akira Ohtake(2), Kenji Ohyama(1), Nobuo Matsuura(4), Nozomu Sasaki(2)
(1)Department of Pediatrics, University of Yamanashi, (2)Department of Pediatrics, Saitama Medical University, (3)Department of Pediatrics, Nishisaitama-Chuo National Hospital, (4)Department of Early Childhood Education, Seitoku University, (5)Department of Pediatrics, Yamanashi Kosei Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S617-S617, 2010.

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P13-1-4 Preclinical data of a novel once weekly human growth hormone prodrug

Jan M.Mikkelsen(1), Harald Rau(2), Torben S.Nissen(3), Grethe Rasmussen(1), Ulrich Hersel(2), Thomas Wegge(2), Susanne Kindermann(2), Torben Lessmann(2), Kennett Sprogoe(1)
(1)Ascendis Pharma A/S, (2)Ascendis Pharma GmbH, (3)Ascendis Pharma Inc
ENDOCRINE JOURNAL 57 (suppl.2-2) S617-S617, 2010.

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P13-1-5 A novel human growth hormone XTEN construct(VRS-317)for monthly administration

Jeffrey L.Cleland(1), Nathan Geething(2), Benjamin Spink(2), Andrew Campbell(2), Louise Lee(2), Yi Yao(2), Joshua Silverman(2)
(1)Versartis, Inc, (2)Amunix, Inc
ENDOCRINE JOURNAL 57 (suppl.2-2) S618-S618, 2010.

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P13-1-6 Auxologic and metabolic effect of a once-a-week sustained-release GH in naive children with GHD

Paul Saenger(1), Peter Ferenc(2), Zvi Zadi(3), Conrad Savoy(4), Hyi-Jeong Ji(5), Chi Yeon Lim(5)
(1)Albert Einstein College of Medicine, (2)Buda Childrens Hospital, (3)Hebrew University, (4)Biopartners GmbH, (5)LG Life Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S618-S618, 2010.

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P13-1-7 Efficacy and safety of the treatment of growth hormone deficient children(GHD)with the recombinant hGH Omnitrope:84-month longterm data

Paul H.Saenger(1), Tomasz Romer(2), Ferenc Peter(3), Brygida Koehler(4), Renata Wasikowa(5), Mieczyslaw Walczak(6), Eugeniusz Korman(7), Jerzy Starzyk(8), Alexander Berghout(9), Markus Zabransky(9)
(1)Albert Einstein College of Medicine, Pediatrics, (2)Endocrinology, Children Memorial Health Institute, (3)Endocrinology, BUDA Childrens Hospital, (4)Paediatric Endocrinology & Diabetology, University Hospital, (5)Paediatric Endocrinology, Paediatric Hospital, (6)Paediatrics, Pomeranian Medical University, (7)Paediatric Endocrinology, Paediatric Institute, (8)Paediatric Endocrinology, Polish-American Hospital CMUJ, (9)Development Department Biopharmaceuticals, Sandoz International
ENDOCRINE JOURNAL 57 (suppl.2-2) S618-S618, 2010.

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P13-1-8 Acylated ghrelin transiently increases in neonatal rat pancreas and induces glucose-responsive insulin release in islet beta-cells

Hiroshi Hosoda(1), Naoko Miura(2), Masanori Nakata(3), Mikiya Nakazato(1), Toshihiko Yada(3), Shigetaka Sugihara(2), Kenji Kangawa(1)
(1)National Cardiovascular Center Research Institute, (2)Department of Pediatrics, Tokyo Women's Medical University Daini Hospital, (3)Division of Integrative Physiology, Department of Physiology, Jichii Medical University school of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S618-S619, 2010.

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P13-2-1 CNP mutant Lbab mouse as a novel model for skeletal dysplasia

Eri Kondo(1), Akihiro Yasoda(1), Toshihito Fujii(1), Takehito Tsuji(2), Go Yamada(1), Takuo Nambu(1), Misa Saijo(1), Masako Miura(1), Naotetsu Kanamoto(1), Masakatsu Sone(1), Naohisa Tamura(1), Hiroshi Arai(1), Kazuwa Nakao(1)
(1)Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, (2)Graduate School of Natural Science and Technology, Okayama University
ENDOCRINE JOURNAL 57 (suppl.2-2) S619-S619, 2010.

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P13-2-2 Association of vitamin D receptor gene polymorphism with vitamin D deficiency

Sachiko Kitanaka(1), Tsuyoshi Isojima(1), Chikahiko Numakura(2), Kiyoshi Hayasaka(2), Takashi Igarashi(1)
(1)Department of Pediatrics, Graduate School of Medicine, The Unversity of Tokyo, (2)Department of Pediatrics, Yamagata University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S619-S619, 2010.

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P13-2-3 Vitamin D status is associated with cardiometabolic risk factors among non-obese children and adolescents

Nasser Al-Daghri(1), Omar Al-Attas(1), Majed Alokail(1), Khalid Alkharfy(2), Mansour Yousef(3), Hesham Nadhrah(3), Abdulaziz Alothman(4), Shaun Sabico(1)
(1)Biochemistry Department, College of Science, King Saud University, (2)College of Pharmacy, King Saud University, (3)Ministry of Health, (4)College of Applied Medical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S619-S619, 2010.

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P13-2-4 Telomere length and childhood obesity among Arab youth

Omar Al-Attas(1), Nasser Al-Daghri(1), Majed Alokail(1), Ahmed Bamakhramah(1), Shaun Sabico(1), Terry Huang(2), Philip McTernan(3), Sudhesh Kumar(3)
(1)Biochemistry Department, King Saud University, (2)Eunice Kennedy Shriver national Institute of Child Health and Human Development, (3)Diabetes and Metabolism Unit, University of Warwick Coventry UK
ENDOCRINE JOURNAL 57 (suppl.2-2) S619-S619, 2010.

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P13-2-5 Clinical variability of LEOPARD syndrome:Study of a new family

Carmen Vulpoi(1), Martin Zenker(2), Mihai Grigoras(3), Ion Poeata(1), Anca Indrei(1), Ioana Vasiliu(1), Jeanina Idriceanu(1), Voichita Mogos(1), Cristina Rusu(1)
(1)University of Medicine and Pharmacy, (2)Universitat Erlangen-Nurnberg, (3)University Hospital St.Spiridon
ENDOCRINE JOURNAL 57 (suppl.2-2) S620-S620, 2010.

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P13-2-6 A case of neonatal nephrogenic diabetes inspidus with AVPR2 mutation

Satoko Shimazu(1), Youko Kataoka(2), Takeshi Usui(1), Hideo Kurosu(2), Souichi Mizuguchi(2), Mioko Mori(2), Yusuke Kishida(2), Tetsuya Ishizuka(2), Yuichi Akiyama(2)
(1)Clinical Research Institute for Endocrine and metabolic Disease, National Hospital Organization Kyoto Medical Center, (2)Department of Pediatrics, National Hospital Organization Kyoto Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S620-S620, 2010.

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P13-2-7 Congenital hypothyroidism caused by a PAX8 gene mutation manifested as sodium/iodide symporter gene defect

Toshihiro Tajima(1), Wakako Jo(1), Kenji Fujieda(2)
(1)Department of Pediatrics Hokkaido University Sapporo, (2)Department of Pediatrics, Asahikawa Medial College
ENDOCRINE JOURNAL 57 (suppl.2-2) S620-S620, 2010.

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P13-2-8 Prenatal treatment of dexamethasone and additional surgical intervention for a female patient with congenital adrenal hyperplasia resulting from 21-hydroxylase deficiency

Mahoko Furujo(1), Toshihide Kubo(1), Takeshi Asai(2), Koji Aoyama(2)
(1)Department of Pediatrics, Okayama Medical Center, (2)Department of Pediatric Surgery, Okayama Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S620-S620, 2010.

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P13-3-1 Survey of drug abuse in American football players in Japan:Analysis of consultations on the bulletin board of an internet sports website

Masato Takahashi(1), Yukitoshi Tatsugi(1), Tosihiko Kohno(2)
(1)Faculty of Physical Education, International Budo University, (2)Faculty of Health Science, Ryotokuji University
ENDOCRINE JOURNAL 57 (suppl.2-2) S620-S621, 2010.

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P13-3-2 Glucose and lipid metabolic disturbances in non-obese cancer survivors of bone marrow transplantation(BMT)in childhood

Takashi Hamajima(1), Naoko Maeda(2), Nobuhiko Suganuma(3), Keizo Horibe(4)
(1)Department of pediatric endocrinology and metabolism, Aichi children's health and medical center, (2)Department of pediatrics, Nagoya Medical Center, (3)Department of human health sciences, Kyoto university graduate school of medicine, (4)Clinical research center, Nagoya medical center
ENDOCRINE JOURNAL 57 (suppl.2-2) S621-S621, 2010.

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P13-3-3 Longitudinal study of thyroid function in girls with turner syndrome

Yasusada Kawada(1), Shunsuke Araki(2), Rinko Kawagoe(2), Kazuhiro Kubo(2), Yukiyo Yamamoto(2)
(1)The Department of Pediatrics, Kyushu Rousai Hospital, (2)Department of Pediatrics, University of Occupational and Environmental Health
ENDOCRINE JOURNAL 57 (suppl.2-2) S621-S621, 2010.

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P13-3-4 Japanese brothers with gynecomastia associated with aromatase excess syndrome

Tomoaki Sano(1), (3), Kenji Ohyama(1), Yoshiko Nakagomi(1), Hiroshi Nakagomi(2), Koji Kobayashi(1), Kisho Kobayashi(1), Tomohiro Saito(1), Masanori Ohta(1), Kazumasa Sato(1), Hideaki Yagasaki(1), Yumiko Mitsui(1), Kenjiro Nagamine(1), Tomonobu Hasegawa(4), Keiko Honma(5), Maki Fukami(6)
(1)Department of Pediatric, University of Yamanashi, (2)Department of Breast Surgery, Yamanashi Prefectural Central Hospital, (3)Department of Pediatrics, Yamanashi Red Cross Hospital, (4)Department of Pediatrics, Keio University, (5)Keio University Hospital, (6)National Research Institute for Child Health and Development
ENDOCRINE JOURNAL 57 (suppl.2-2) S621-S621, 2010.

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P13-3-5 Health care status of adolescent and adult Turner women in Japan

Keinosuke Fujita(1), Takahiro Mochizuki(1), Susumu Yokoya(2)
(1)Department of Pediatrics, Children's Medical Center, Osaka City General Hospital, (2)Department of Medical Subspeciarities, National Center of Child Health and Developement
ENDOCRINE JOURNAL 57 (suppl.2-2) S621-S622, 2010.

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P13-3-6 Obesity prevalence and risk factors of school children aged 6-15 years in Erzurum

Ahmet Turgut, Zerrin Orbak
Ataturk University, Department of Pediatric Endocrinology
ENDOCRINE JOURNAL 57 (suppl.2-2) S622-S622, 2010.

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P13-3-7 Obesity and type 2 diabetes in Chinese children

Gary W.K.Wong, H C Yau, Ling Ling Cheng
Department of Paediatrics, Chinese University of Hong Kong
ENDOCRINE JOURNAL 57 (suppl.2-2) S622-S622, 2010.

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P14-1-1 Distinct pattterns of intracellular signals generated by sweet taste receptor agonists in MIN6 cells

Yuko Nakagawa(1), Masahiro Nagasawa(1), Satoko Yamada(1), Akemi Hara(1), Hideo Mogami(2), Martin J.Lohse(3), Yuzo Ninomiya(4), Itaru Kojima(1)
(1)Department of Cell Physiology, Institute for Molecular and Cellular Regulation, Gunma University, (2)Department of Physiology, Hamamatsu Medical School, (3)Institute of Pharmacology and Toxicology, University of Wurzburg, (4)Section of Oral Neuroscience, Graduate School of Dental Science, Kyushu University
ENDOCRINE JOURNAL 57 (suppl.2-2) S622-S622, 2010.

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P14-1-2 Leucine modulates contraction-and insulin-stimulated glucose transport and upstream signaling events in rat skeletal muscle

Nobumasa Iwanaka, Tatsuro Egawa, Nozomi Satoubu, Kouhei Karaike, Xiao Ma, Shinya Masuda, Tatsuya Hayashi
Graduate School of Human and Environmental Studies, Kyoto University
ENDOCRINE JOURNAL 57 (suppl.2-2) S622-S622, 2010.

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P14-1-3 A novel insulin signaling molecule, APPL1

Tsugumichi Saito(1), Shuichi Okada(1), Kihachi Oshima(2), Takafumi Tsuchiya(1), Hiroki Takahashi(1), Hiroyuki Shimizu(1), Masatomo Mori(1)
(1)Department of Medicine and Molecular Science, Gunma University, (2)Health Administration Center, Gunma University
ENDOCRINE JOURNAL 57 (suppl.2-2) S623-S623, 2010.

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P14-1-4 Regulation of insulin granule exocytosis by glucose

Tadao Shibasaki(1), Harumi Takahashi(1), Susumu Seino(1), (2), (3)
(1)Division of Cellular and Molecular Medicine, Kobe University Graduate School of Medicine, (2)Diabetes, Metabolism and Endocrinology, Kobe University Graduate School of Medicine, (3)CREST
ENDOCRINE JOURNAL 57 (suppl.2-2) S623-S623, 2010.

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P14-1-5 Role of FOXO3a in gonadotropin-releasing hormone-induced cell growth inhibition

Emmanouil Stavrou, Robert P Millar, Adam J Pawson
MRC Human Reproductive Sciences Unit, The Queen's Medical Research Institute, University of Edinburgh
ENDOCRINE JOURNAL 57 (suppl.2-2) S623-S623, 2010.

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P14-1-6 Expression of micro RNA 21 in mammary stem cells is controlled by cytokine-STAT5 signaling

Avi Shamay(1), (2), Yonatan Feuermann(2), Peter Klover(2), D.Yamaji(2), G.W.Robinson(2), Lothar Hennighausen(2)
(1)Institute of Animal Science, Agricultural Research Organization, the Volcani Center, (2)Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
ENDOCRINE JOURNAL 57 (suppl.2-2) S623-S623, 2010.

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P14-1-7 Analysis of vasopressin V2 receptor mutants in partial nephrogenic diabetes insipidus and their functional rescue by pharmacologic chaperones

Noriko Makita(1), Katsunori Manaka(1), Kazuhiro Takahashi(2), junichiro Sato(1), Atsuro Oishi(1), yuki Yajima(1), Makiko Hashimoto(1), Koji Sekine(3), Takashi Igarashi(2), Toshiro Fujita(1), Taroh Iiri(1)
(1)Department of Endocrinology and Nephrology, The University of Tokyo, (2)Department of Pdiatrics, The University of Tokyo, (3)Toho University Ohashi Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S623-S624, 2010.

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P14-1-8 Induction of CTGF and uPA but not NF-IL3A by calcitonin is dependent on Erk1/2 phosphorylation in renal cell line

Misa Nakamura(1), Takashi Ozaki(2), Ichiro Mori(2)
(1)Department of Rehabilitation, Osaka Kawasaki Rehabilitation University, (2)Department of Pathology, Wakayama Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S624-S624, 2010.

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P14-2-1 Activation of extracellular signal-regulated kinase(ERK)and induction of mitogen-activated protein kinase phosphatase 1(MKP1)by perifused thyrotropin-releasing hormone(TRH)stimulation in rat pituitary GH3 Cells

Aki Oride, Haruhiko Kanasaki, Indri Purwana, Kohji Miyazaki
The Department of Obstetrics and Gynecology, Shimane University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S624-S624, 2010.

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P14-2-2 Induction of mitogen-activated protein phosphatase-1(MKP1)by gonadotropin-releasing hormone(GnRH)and the role for gonadotropin subunit gene expression in pituitary gonadotroph LβT2 cells

Indri N Purwana, Haruhiko Kanasaki, Aki Oride, Kohji Miyazaki
Department of Obstetrics and Gynecology, Shimane University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S624-S624, 2010.

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P14-2-3 Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via EGF receptor-mediated ERK and Akt activation pathway

Hirofumi Hitomi(1), Gang Liu(1), Naohisa Hosomi(2), Daisuke Nakano(1), Hideyasu Kiyomoto(2), Masakazu Kohno(2), Atsuhiro Ichihara(3), Hiroshi Itoh(3), Akira Nishiyama(1)
(1)Department of Pharmacology, Kagawa University, (2)Department of Cardiorenal and Cerebrovascular Medicine, Kagawa University, (3)Anti-Aging Medicine & Endocrinology and Internal Medicine, Keio University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S624-S625, 2010.

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P14-2-4 IGF-1 induces cellular senescence via reactive oxygen species in vascular smooth muscle cells

Anastasia Evi Handayaningsih(1), Genzo Iguchi(1), Hidenori Fukuoka(1), Hitoshi Nishizawa(1), Michiko Takahashi(1), Masaaki Yamamoto(1), Elizabeth-Henny Herningtyas(2), Yasuhiko Okimura(2), Hidesuke Kaji(3), Kazuo Chihara(4), Susumu Seino(1), (5), Yutaka Takahashi(1)
(1)Division of Diabetes, Metabolism and Endocrinology, Kobe University Graduate School of Medicine, (2)Division of Basic Allied Medicine, Kobe University Graduate School of Health Science, (3)Division of Physiology/Metabolism, University of Hyogo, (4)Hyogo Prefectural Kakogawa Hospital, (5)Division of Cellular and Molecular Medicine, Kobe University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S625-S625, 2010.

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P14-2-5 Expression and probable role of extracellular signal-regulated protein kinases in streptozotocin-induced diabetic rats and the protection of Tongluo Recipe

Wenjia Tang, Yuwei Xing, Junjie Zou, Zhimin Liu
Shanghai Changzheng Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S625-S625, 2010.

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P14-2-6 Two ghrelin receptors in goldfish

Hiroyuki Kaiya(1), Tohru Miura(2), Kouhei Matsuda(2), Mikiya Miyazato(1), Kenji Kangawa(1)
(1)Department of Biochemistry, National Cardiovascular Center Research Institute, (2)Laboratory of Regulatory Biology, Graduate School of Science and Engineering, University of Toyama
ENDOCRINE JOURNAL 57 (suppl.2-2) S625-S625, 2010.

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P14-2-7 Identification and characterization of a D12 mega size complex

Sally Nakamura-Fujiyama(1), (2), Saya Ito(1), (2), Shun Sawatsubashi(1), (2), Eriko Suzuki(1), (2), Masahiko Tanabe(1), (2), Shuhei Kimura(1), Takashi Ueda(1), Takuya Murata(1), Ken-ichi Takeyama(1), Shigeaki Kato(1), (2)
(1)Institute of Molecular and Cellular Biosciences, University of Tokyo, (2)ERATO, Japan Science and Technology Agency
ENDOCRINE JOURNAL 57 (suppl.2-2) S625-S626, 2010.

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P14-2-8 Proposal for integrated network systems and evolutionary developmental endocrinology(ins-eden)

Hiroyuki Koshiyama(1), Yoshihiro Ogawa(2), Kiyoshi Tanaka(3), Issei Tanaka(4)
(1)Center for Diabetes & Endocrinology, Medical Research Institute Kitano Hospital, (2)Department of Molecular Medicine and Metabolism, Medical Research Institute, Tokyo Medical and Dental University, (3)Department of Food and Nutrition, Kyoto Women's University, (4)Hirakata Kosai Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S626-S626, 2010.

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P15-1-1 A case of adrenocortical oncocytoma associated with aldosteronoma

Ken Terui(1), Satoru Sakihara(1), Yuki Matsuhashi(1), Akihito Kon(1), Takeshi Nigawara(1), Hironobu Sasano(2), Toshihiro Suda(1)
(1)Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, (2)Department of Pathology, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S626-S626, 2010.

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P15-1-2 Physiologic variance of corticotrophin affects diagnosis in adrenal vein sampling

Eikan Mishima, Masayuki Tanemoto, Yoichi Takeuchi, Takehiro Suzuki, Takaaki Abe, Sadayoshi Ito
Division of Nephrology, Hypertension and Endocrinology, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S626-S626, 2010.

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P15-1-3 Re-evaluate how to screen and confirm primary aldosteronism

Masao Omura(1), (3), Kohzoh Makita(2), Toshikazu Saito(3), Tetsuo Nishikawa(1)
(1)Department of Endocrinology & Metabolism, Yokohama Rosai Hospital, (2)Department of Radiology, Tokyo Kita Social Insurance Hospital, (3)Department of Endocrinology & Metabolism, Social Insurance Central General Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S626-S627, 2010.

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P15-1-4 Concordant and disconcordant results of localization by adrenal CT and venous sampling(AVS)in primary aldosteronism(PA)

Kazutaka Nanba(1), Tamiko Tamanaha(1), Masashi Kuroda(2), Yoriko Sakene-Ueda(1), Satoko Shimazu(1), Hidenari Nomura(1), Hiroshi Okuno(3), Takeshi Usui(1), Tetsuya Tagami(1), Akira Shimatsu(1), Mitsuhide Naruse(1)
(1)Department of Endocrinology and Metabolic Disease, NHO Kyoto Medical Center, (2)Department of Radiology, NHO Kyoto Medical Center, (3)Department of Urology, NHO Kyoto Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S627-S627, 2010.

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P15-1-5 Endocrinological evaluation of successful sampling from right adrenal veins in patients with primary aldosteronism

Ryo Morimoto(1), Fumitoshi Satoh(1), Masataka Kudo(1), Osamu Murakami(1), Yoshitsugu Iwakura(1), Kei Takase(2), Tadashi Ishibashi(2), Shoki Takahashi(2), Shigeto Ishidoya(3), Yoichi Arai(3), Yasuhiro Nakamura(4), Takashi Suzuki(4), Hironobu Sasano(4), Sadayoshi Ito(1)
(1)Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Graduate School of Medicine, (2)Department of Diagnostic Radiology, Tohoku University Graduate School of Medicine, (3)Department of Urology, Tohoku University Graduate School of Medicine, (4)Department of Pathology, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S627-S627, 2010.

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P15-1-6 Adrenal incidentaloma in a Hong Kong Chinese cohort

Chun-chung Chow, Vanessa W.S.Ng, Ronald C.W.Ma, Alice P.S.Kong, Wing-Yee So
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong
ENDOCRINE JOURNAL 57 (suppl.2-2) S627-S627, 2010.

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P15-1-7 Adrenal incidentaloma:Are they really sinister? A retrospective analysis at a tertiary specialist centre

Edwin AC Chng, Rinkoo Dalan, Michelle Jong
Department of Endocrinology, Tan Tock Seng Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S627-S627, 2010.

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P15-1-8 Differential diagnosis of primary aldosteronism by ACTH-stimulated adrenal vein sampling:an institutional experience

Satoshi Yamagata(1), Norio Wada(1), Yutaka Dannoura(1), Shinji Obara(1), Katsuyuki Yanagisawa(1), Mitsuru Sugiura(2), Chihoko Miyazaki(2)
(1)Department of Diabetes and Endocrinology, Sapporo City General Hospital, (2)Department of Diagnostic Radiology, Sapporo City General Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S628-S628, 2010.

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P15-2-1 Endothelial dysfunction in Cushing's syndrome

Itaru Akaza, Takanobu Yoshimoto, Kyoichiro Tsuchiya, Yukio Hirata
Department of Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate School
ENDOCRINE JOURNAL 57 (suppl.2-2) S628-S628, 2010.

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P15-2-2 Cushing syndrome in patient with thyroid orbitopathy(case report)

Peter Vanuga, Dusan Pavai, Mikulas Pura
Department of Endocrinology, National Institute of Endocrinology and Diabetology
ENDOCRINE JOURNAL 57 (suppl.2-2) S628-S628, 2010.

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P15-2-3 Characteristic of metabolic abnormalities in vasopressin responders with subclinical Cushing's syndrome

Sawako Suzuki, Daigaku Uchida, Hisashi Koide, Keiko Suyama, Tomohiko Yoshida, Tomoaki Tanaka, Kotaro Yokote, Ichiro Tatsuno
Clinical Cell Biology, Chiba University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S628-S629, 2010.

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P15-2-4 Assessment of urinary cortisol excretion levels by different immunoassay kits for diagnosis of subclinical Cushing's syndrome

Tsuguka Shiwa, Kenji Oki, Masatoshi Hirano, Shusaku Maeda, Takako Asao, Takafumi Sugihiro, Tomokazu Awaya, Shuhei Nakanishi, Kiminori Yamane, Nobuoki Kohno
Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University
ENDOCRINE JOURNAL 57 (suppl.2-2) S629-S629, 2010.

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P15-2-5 Efficacy of high-dose dexamethasone suppression test for diagnosis of subclinical Cushing's syndrome

Mami Shiwa, Kenji Oki, Tsuguka Shiwa, Masatoshi Hirano, Shusaku Maeda, Yu Sakashita, Tomokazu Awaya, Shuhei Nakanishi, Kiminori Yamane, Nobuoki Kohno
Depertment of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University
ENDOCRINE JOURNAL 57 (suppl.2-2) S629-S629, 2010.

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P15-2-6 Establishment of a management protocol for subclinical Cushing's syndrome and nonfunctioning aderenocortical adenoma

Toshiaki Tanaka(1), Takeshi Maehana(1), Naoki Itoh(2), Naoya Masumori(1), Taiji Tsukamoto(1)
(1)Department of Urology, Sapporo Medical University, (2)Department of Urology, Sapporo Medical Center NTT East
ENDOCRINE JOURNAL 57 (suppl.2-2) S629-S629, 2010.

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P15-2-7 Clinical courses and therapeutic procedures of bilateral adrenal incidentalomas with ACTH-independent cortisol secretion

Yugo Kanai, Yui Yamashita, Shin Yonemitsu, Ken Masatsugu, Seiji Muro, Shogo Oki
Department of Diabetes and Endocrinology, Osaka Redcross Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S629-S629, 2010.

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P15-2-8 Dexametasone screening test(DST)in a large Brazilian family with hereditary cortisol-secreting 5HT4R responsive ACTH independent macronodular adrenal hyperplasia(AIMAH)reveals unsuspected subclinical Cushing's syndrome(CS)

Guilherme A.Alencar(1), (2), Isabelle Bourdeau(2), Antonio M.Lerario(1), (2), Berenice B.Mendonca(1), Andre Lacroix(2), Maria Candida V.Fragoso(1), (2)
(1)Division of Endocrinology, Department of Medicine, Hospital das Clinicas Sao Paulo University, (2)Division of Endocrinology, Department of MedicineCentre hospitalier de I Universite de Montreal(CHUM)
ENDOCRINE JOURNAL 57 (suppl.2-2) S630-S630, 2010.

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P15-3-1 A National survey of adrenal incidentalomas in Japan

Takamasa Ichijo(1), (2), Hajime Ueshiba(2), Naoki Hiroi(2), Kumiko Tsuboi(2), Mariko Higa(1), Gen Yoshino(2)
(1)Division of Diabetes and Endocrinology, Department of Internal Medicine, Saiseikai Yokohama-city Tobu Hospital, (2)Division of Diabetes, Metabolism and Endocrine, Department of Internal Medicine, Toho University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S630-S630, 2010.

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P15-3-2 A first-reported case of cortisol-producing adenoma, co-existed with thyroid follicular carcinoma inside the adrenal gland

Jun Saito(1), Masao Omura(1), Takashi Katagiri(2), Shugo Hanyu(3), Hironobu Sasano(1), (4), Tetsuo Nishikawa(1)
(1)Department of Endocrinology & Metabolism, Yokohama Rosai Hospital, (2)Department of Medicine, Kariwagun General Hospital, (3)Department of Urology, Kariwagun General Hospital, (4)Department of Pathology, Tohoku University of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S630-S630, 2010.

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P15-3-3 Gland adrenocortical carcinoma with prominent hepatic metastasis accompanying serious hypopotassemia

Kennosuke Ohashi(1), Tomoko Ito(1), Izumi Yamaguchi(1), Nozomu Nakai(1), Takanori Ebisawa(1), Hideaki Kurata(1), Katsuyoshi Tojo(2), Naoko Tajima(2), Hironobu Sasano(3)
(1)Division of Diabetes and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine Aoto Hospital, (2)Dlvision of Diabetes and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine Hospital, (3)Department of Pathology, Tohoku University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S630-S631, 2010.

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P15-3-4 Serum concentrations of TNF α and its soluble receptors in patients with adrenal tumors treated by surgery

Jan Komorowski(1), Jolanta Jurczynska(1), Tomasz Stepien(2), Krzysztof Kolomecki(2), Krzysztof Kuzdak(2), Henryk Stepien(3)
(1)Department of Clinical Endocrinology, The First Chair of Endocrinology, Medical University of Lodz, (2)Department of Endocrine and General Surgery, The First Chair of Endocrinology, Medical University of Lodz, (3)Department of Immunoendocrinology, The First Chair of Endocrinology, Medical University of Lodz
ENDOCRINE JOURNAL 57 (suppl.2-2) S631-S631, 2010.

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P15-3-5 Adrenal myelolipoma:Case report with distinctive imaging and pathological features

Li-Ying Huang
Department of Urology, College of Medicine, National Taiwan University
ENDOCRINE JOURNAL 57 (suppl.2-2) S631-S631, 2010.

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P15-3-6 A giant myelolipoma as an adrenal incidentaloma:a case report with radiologic, endocrine and pathologic evaluation

Mark Anthony S.Sandoval, Joselynna Anel-Quimpo
Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, Philippine General Hospital, University of the Philippines Manila
ENDOCRINE JOURNAL 57 (suppl.2-2) S631-S631, 2010.

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P15-3-7 The calcium antagonists affect the expression of the steroidogenic enzyme in human adrenocarcinoma(NCI H295R)cells

Tsuyoshi Isaka(1), Keiichi Ikeda(2), Yuko Takada(1), Katsuyoshi Tojo(1), Naoko Tajima(1)
(1)Division of Diabetes Metabolism and Endocrinology Department of Internal Medicine The Jikei University School of Medicine, (2)Department of Pharmacology
ENDOCRINE JOURNAL 57 (suppl.2-2) S631-S632, 2010.

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P15-3-8 Angiogenic factors in adrenal tumors and responce of the adrenal cells to a multikinase and mTOR inhibitors

Barbara Mariniello(1), Beatrice Rubin(1), Anna Patalano(1), Maria-Verena Cicala(1), Raffaele Pezzani(1), Isabella Finco(1), Claudia Radu(2), Maurizio Iacobone(3), Franco Mantero(1)
(1)Division of Endocrinology, Department of Surgical and Medical Sciences, University of Padua, (2)Department of Cardiologic, Thoracic and Vascular Sciences, University of Padua, (3)Division of Endocrine Surgery, University of Padua
ENDOCRINE JOURNAL 57 (suppl.2-2) S632-S632, 2010.

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P15-3-9 A case of multiple lung metastases from adrenocortical carcinoma

Hanae Hagiwara
Kuma Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S632-S632, 2010.

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P15-4-1 Genetic analysis of 28 patients of pheochromocytoma/paraganglioma in Japan

Takeshi Usui(1), Sho Hashimoto(2), Rika Yamashita(3), Kazuro Kaise(3), Yuji Aoki(4), Yuko Yambe(5), Tetsuya Tagami(1), Akira Shimatsu(1), Mitsuhide Naruse(1)
(1)Clinical Research Institute for Endocrine and Metabolic Diseases, National Hospital Organization Kyoto Medical Center, (2)Department of Otolaryngology, National Hospital Organization Sendai Medical Center, (3)Department of Internal Medicine, National Hospital Organization Sendai Medical Center, (4)Department of Internal Medicine, National Hospital Organization Matsumoto Hospital, (5)Department of Endocrinology and Metabolism, National Hospital Organization Nagoya Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S632-S632, 2010.

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P15-4-2 Diversity of pheochromocytomas/paragangliomas in clinical practice

Yui Yamashita, Yugo Kanai, Shin Yonemitsu, Ken Masatsugu, Seiji Muro, Shogo Oki
Department of Diabetes and Endocrinology, Osaka Red Cross Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S632-S633, 2010.

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P15-4-3 Pheochromocytoma associated with severe intestinal pseudo-obstruction:A case report

Kenta Kanazawa(1), Kei Endo(1), Hitoshi Yanaihara(2), Hiraku Ono(1), Akinobu Minagawa(1), Masako Hatano(1), Miho Senda(1), Takuya Awata(1), Shigehiro Katayama(1), Hiroshi Yamaguchi(3), Masanori Yasuda(3)
(1)Department of Endocrinology and Diabetes, Saitama Medical University, (2)Department of Urology, Saitama Medical University, (3)Department of Pathology, Saitama International Medical Center, Saitama Medical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S633-S633, 2010.

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P15-4-4 Genetic study of thai patients with pheochromocytoma and/or paraganglioma, an experience from single tertiary center

Thiti Snabboon, Natnicha Houngngam, Sompongse Suwanwalaikorn, Vitaya Sridama, Sarat Sunthomyothin
Department of Internal Medicine, Faculty of Medicine, Chulalongkorn University
ENDOCRINE JOURNAL 57 (suppl.2-2) S633-S633, 2010.

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P15-4-5 Pheocromocytoma at extreme ages-2 cases report

Catalina Poiana(1), (2), Mara Carsote(1), Ramona Samoila(2), Corina Chirita(2), Anda Dumitrascu(2), Dan Hortopan(2), Mircea Beuran(3), Sorin Paun(3), Ionel Sinescu(4), Monica Hortopan(4), Dana Terzea(1), (2), (5)
(1)Department of Endocrinology, Carol Davila University of Medicine and Pharmacy, (2)CI Parhon National Institute of Endocrinology, (3)Floreasca Emergency Hospital, (4)Fundeni Clinical Institute, (5)Babes National Institute of Research and Development
ENDOCRINE JOURNAL 57 (suppl.2-2) S633-S633, 2010.

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P15-4-6 Extensive cave vein thrombosis and Cushing disease-case presentation

Catalina Poiana(1), Mara Carsote(1), Ramona Samoila(2), Corina Chirita(2), Dumitru Ioachim(2), Dan Hortopan(2), Bogdan Stanescu(1), (2), Cristina Corneci(2), Mihail Coculescu(1), (2)
(1)Department of Endocrinology, Carol Davila University of Medicine and Pharmacy, (2)C.I.Parhon National Institute of Endocrinology
ENDOCRINE JOURNAL 57 (suppl.2-2) S633-S634, 2010.

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P15-4-7 Extra adrenal paraganglioma in an achandroplasia patient-case report

Reddy K.Somashekara, A.N.Roopa, Padmini Jayachandran, M.N.Suma
MVJ Medical College & Research hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S634-S634, 2010.

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P15-4-8 Clinical, hormonal, and genetic profile of filipino patients with suspected pheochromocytoma(preliminary report)

Leilani B.Mercado-Asis(1), Stefanie W.Lim-Uy(1), Analyza M.Galia(1), Lucy Anne E.Mamba(1), Aileen Y.Sia-Atanacio(1), Albert L.Chu(1), Zarina G.Lorenzo(1), Ma.Louella M.Padua(1), Aurora G.Macaballug(1), Jay S.Fonte(1), (2), Jeremyjones F.Robles(1), (2), Karel Pacak(2)
(1)Section of Endocrinology and Metabolism, University of Santo Tomas Hospital, (2)Reproductive and Adult Endocrinology Program, Section on Medical Neuroendocrinology, National Institutes of Health/National Instituted for Child Health and Human Development
ENDOCRINE JOURNAL 57 (suppl.2-2) S634-S634, 2010.

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P15-5-1 Measurements of aldosterone in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry(LC-ESI-MS/MS):Comparison to radioimmunoassays

Masataka Kudo(1), Fumitoshi Satoh(1), Ryo Morimoto(1), Osamu Murakami(1), Akira Sugawara(2), Akira Uruno(3), Kouwa Yamashita(4), Mitsuteru Numazawa(4), Sadayoshi Ito(1)
(1)Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, (2)Department of Advanced Biological Sciences for Regeneration, Tohoku University Graduate School of Medicine, (3)Department of Biochemistry, Tohoku University Graduate School of Medicine, (4)Faculty of Pharmaceutical Science, Tohoku Pharmaceutical University
ENDOCRINE JOURNAL 57 (suppl.2-2) S634-S634, 2010.

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P15-5-2 Primary aldosteronism is frequently associated with subclinical Cushing's syndrome

Kiichiro Hiraishi(1), Takanobu Yoshimoto(1), Kyoichiro Tsuchiya(1), Hajime Izumiyama(1), Masaru Doi(1), Hironobu Sasano(2), Yukio Hirata(1)
(1)Department of Clinical and Molecular Endocrinology, Tokyo Medical and Dental University Graduate School, (2)Department of Pathology, Tohoku University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S634-S635, 2010.

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P15-5-3 Reevaluation of ACTH stimulation in adrenal venous sampling for the diagnosis of primary aldosteronism

Akiyo Tanabe(1), Mika Tsuiki(1), Aya Tsumagari(1), Hitomi Kimura(1), Ryohei Kuwatsuru(1), Mitsuhide Naruse(2), Kazue Takano(1)
(1)Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, (2)Division of Endocrinology, Clinical Research Institute of Endocrine and Metabolic Diseases, Kyoto Medical Center, National Hospital Organization
ENDOCRINE JOURNAL 57 (suppl.2-2) S635-S635, 2010.

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P15-5-4 Radioimmunoassay of aldosterone may lead a misdiagnosis of localization by adrenal venous sampling(AVS)in primary aldosteronism(PA)

Hidenari Nomura(1), Kazutaka Nanba(1), Yoriko Sakene-Ueda(1), Satoko Shimazu(1), Tamiko Tamanaha(2), Hiroshi Okuno(1), Takeshi Usui(1), Tetsuya Tagami(1), Akira Shimatsu(1), Mitsuhide Naruse(1)
(1)Department of Endcrinology and Metabolism, National Hospital Organization Kyoto Medical Center, (2)Department of Urology, National Hospital Organization Kyoto Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S635-S635, 2010.

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P15-5-5 Leptin and its receptor in human adrenal and tumors

Shi Chen(1), Zhengpei Zeng(1), Hanzhong Li(2), Anli Tong(1), Lin Lu(1), Ailin Song(1), Ming Li(1), Wei Liang(1), Na Man(1), Cai-Xia Cao(1)
(1)Department of Endocrinology, Peking Union Medical College Hospital, (2)Department of Uronology, Peking Union Medical College Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S635-S635, 2010.

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P15-5-6 The mRNA expression of adiponectin receptor 1 and 2 in human adrenal and tumors

Shi Chen(1), Zhengpei Zeng(1), Hanzhong Li(2), Anli Tong(1), Lin Lu(1), Ailin Song(1), Ming Li(1), Wei Liang(1), Na Man(1), Cai-Xia Cao(1)
(1)Dept.of Endocrinology, Peking Union Medical College Hospital, (2)Dept.of Uronology, Peking Union Medical College Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S635-S635, 2010.

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P15-5-7 Evaluation of right adrenal vein by MDCT-for accurate localization of aldosterone hypersecretion by selective adrenal venous sampling-

Kei Takase(1), Fumitoshi Satoh(2), Ryo Morimoto(2), Kazumasa Seiji(1), Masashi Tsuda(1), Takayuki Yamada(1), Sadayoshi Ito(2), Shoki Takahashi(1)
(1)Department of Diagnostic Radiology, Tohoku University, (2)Department of Endocrinology, Tohoku University
ENDOCRINE JOURNAL 57 (suppl.2-2) S636-S636, 2010.

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P15-5-8 Plasma aldosterone concentration and renin activity in primary aldosteronism and pheochromocytoma

Ai-ling Song, Zhengpei Zeng, Anli Tong, Cai-Xia Cao, Lin Lu, Shi Chen, Ming Li
Department of Endocrinology, Peking Union Medical College hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
ENDOCRINE JOURNAL 57 (suppl.2-2) S636-S636, 2010.

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P15-6-1 Sympathetic-activity induced salt-sensitive hypertension invovled of WNKs

Shengyu Mu(1), Tatsuo Shimosawa(2), Sayoko Ogua(1), Fumiko Mori(1), Hong Wang(1), Yuzaburo Uetake(1), Shinichi Uchida(3), Toshiro Fujita(1)
(1)The Department of nepherology and endocrinology, University of Tokyo, (2)Faculty of Medicine Dept.of Clinical Laboratory, University of Tokyo, (3)Department of nephrology, Tokyo Medical and Dental Unirersity
ENDOCRINE JOURNAL 57 (suppl.2-2) S636-S636, 2010.

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P15-6-2 Interactions in cortisol secretion by multiple hormone stimulation in primary cultured adrenal cells from a case with food-dependent Cushing syndrome(FDCS)

Hiroshi Koso(1), Koji Morita(1), Mieno Konishi(1), Tsutomu Kodera(1), Yoshiaki Ihara(1), Kunihisa Hamano(1), Takashi Hinata(1), Rie Yoshida(1), Keiichi Ito(3), Tomohiko Asano(3), Fumihiko Kimura(2), Yuji Tanaka(1)
(1)Department of Internal Medicine, Division of Endocrinology and Metabolism, National Defense Medical College, (2)Department of Internal Medicine, National Defense Medical College, (3)Department of Urology, National Defense Medical College
ENDOCRINE JOURNAL 57 (suppl.2-2) S636-S637, 2010.

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P15-6-3 Improvement of hypercortisolism by unilateral adrenalectomy and β-blocker therapy in subclinical Cushing's syndrome associated with ACTH-independent macronodular adrenocortical hyperplasia

Maiko Mouri
Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University
ENDOCRINE JOURNAL 57 (suppl.2-2) S637-S637, 2010.

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P15-6-4 Serotonin receptor in aldosterone producing adenoma:Implication for aldosterone secretion

Isamu Miyamori(1), Miki Fujii(1), Satoru Inaba(1), Isao Inoki(1), Tadashi Konoshita(1), Yoshiyu Takeda(2), Takashi Yoneda(2), Shigehiro Karashima(2)
(1)The Third Department of Internal Medicine, University of Fukui, (2)Department of Internal Medicine, Graduate School of Medical Science, Kanazawa University
ENDOCRINE JOURNAL 57 (suppl.2-2) S637-S637, 2010.

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P15-6-5 High density lipoprotein subfraction 2(HDL2)stimulates expression of aldosterone synthase(CYP11B2)in human adrenocorticoid cells

Yewei Xing(1), Sandhya Sankaranarayanan(2), Ginny Weibel(2), Omar Francone(3), William E.Rainey(1)
(1)The department of physiology, Medical College of Georgia, (2)Joseph Stokes Jr.Research Institute, Children's Hospital of Philadelphia, (3)Department of Atherosclerosis Biology, Pfizer Global Research and Development
ENDOCRINE JOURNAL 57 (suppl.2-2) S637-S637, 2010.

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P15-6-6 Role of adrenal androgens in women's sexual dysfunction

Fernand Labrie(1), Rosemary Basson(2), Lori Brotto(3), John Petkau(4)
(1)Laval University Hospital Research Center(CRCHUL)and Laval University, (2)Department of Psychiatry, University of British Columbia, Vancouver Hospital, (3)Department of Obstetrics and Gynaecology, University of British Columbia, (4)Department of Statistics, University of British Columbia
ENDOCRINE JOURNAL 57 (suppl.2-2) S637-S638, 2010.

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P15-6-7 Effects of working at night on circadian rhythm of cortisol

Fumihisa Miyauchi
Clinical Research Center for Working Women's Health, Japan Labour Health and welfare Organization
ENDOCRINE JOURNAL 57 (suppl.2-2) S638-S638, 2010.

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P15-6-8 Disrupted glucose homeostasis as a mechanism underlying the transformation of physiological gastroprotective action of glucocorticoids to pathological ulcerogenic effect

Liudmila P.Filaretova, Olga Yu.Morozova, Tatiana R.Bagaeva, Tatiana T.Podvigina
Laboratory of Experimental Endocrinology, Pavlov Institute of Physiology
ENDOCRINE JOURNAL 57 (suppl.2-2) S638-S638, 2010.

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P15-6-9 Sleep apnea and urinary metanephrine response to continuous positive airway pressure

Jaydira Del Rivero, Alan Sacerdote
Woodhull Medical Center, NYU School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S638-S638, 2010.

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P15-7-1 Evaluation of intima-media thickness of carotid in patients with primary aldosteronism

Kazumi Iino(1), (2), Yutaka Oki(1), Etsuko Hamada(2), Miho Yamashita(1), Kosuke Yogo(1), Masato Maekawa(2), Hirotoshi Nakamura(1)
(1)Second Division, Department of Medicine, Hamamatsu University School of Medicine, (2)Department of Laboratory Medicine, Hamamatsu University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S638-S639, 2010.

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P15-7-2 Ultrasound image analysis of common carotid artery intima-media thickness in patients with primary hyperaldosteronism and essential hypertension

Bohumil Majtan(1), Jaromir Belacek(2), Vit Marousek(2), Jiri Widimsky(1), Robert Holaj(1)
(1)3rd Internal Department, General Teaching Hospital and 1st Faculty of Medicine, Charles University in Prague, (2)Department of Biophysics 1st Faculty of Medicine, Charles University in Prague
ENDOCRINE JOURNAL 57 (suppl.2-2) S639-S639, 2010.

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P15-7-3 The accuracy on the diagnosis of primary aldosteronism by the ratio of plasma aldosterone to renin combining with low renin level

Tieyun Zhao, Fang Li, Xiaoying Xie
Department of Endocrinology and Metabolism, West China Hospital, Sichuan University
ENDOCRINE JOURNAL 57 (suppl.2-2) S639-S639, 2010.

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P15-7-4 What is the clinical significance of masked chronic kidney disease in patients with primary aldosteronism?

Katsutoshi Takahashi, Toshiro Fujita
Department of Nephrology, and Endocrinology, University of Tokyo, Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S639-S639, 2010.

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P15-7-5 No rules without exception:The screening and diagnosis of primary aldosteronism

Katsutoshi Takahashi(1), Hiroaki Nishimatsu(2), Masaaki Akahane(3), Toshiro Fujita(1)
(1)Department of Nephrology and Endocrinology, University of Tokyo, Graduate School of Medicine, (2)Department of Urology, University of Tokyo, Graduate School of Medicine, (3)Department of Radiology, University of Tokyo, Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S639-S640, 2010.

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P15-7-6 Glucose and lipid metabolism in patients with primary aldosteronism

Rie Jo, Hirotaka Shibata, Isao Kurihara, Yuichiro Motosugi, Kazutoshi Miyashita, Ayano Murai-Takeda, Yuko Mitsuishi, Hiroshi Itoh
Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University, School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S640-S640, 2010.

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P15-7-7 Obesity seems to affect prognosis of hypertension in primary aldosteronism after surgical treatment

Yoko Matsuzawa(1), Masao Omura(1), Jun Saito(1), Toshikazu Saito(2), Tetsuo Nishikawa(1)
(1)Department of Endocrinology & Metabolism, Yokohama Rosai Hospital, (2)Department of Endocrinology & Metabolism, Tokyo Social Insurance General Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S640-S640, 2010.

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P15-7-8 The relationship between primary aldosteronism and anxiety or panic disorder

Moritake Higa(1), Hironobu Sasano(2), Masanori Kakazu(3), Masamori shimabuku(4)
(1)Center of Diabetes and Life-style related disease, Tomishiro Central Hospital, (2)Department of Pathology, Tohoku University Graduate School of Medicine, (3)Department of Internal Medicine, Tomishiro Central Hospital, (4)Department of Surgery, Tomishiro Central Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S640-S640, 2010.

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P15-8-1 Adrenal catastrophe:A case report of bilateral adrenal hemorrhage in a patient with antiphospholipid syndrome

Takako Araki(1), Prajesh M Joshi(2), Adrienne M Fleckman(1), (2)
(1)Division of Endocrinology and Metabolism, Beth Israel Medical Center, Albert Einstein College of Medicine, (2)Department of Medicine, Beth Israel Medical Center, Albert Einstein College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S640-S641, 2010.

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P15-8-2 Addison disease and the risk of fractures, a general population-based cohort study

Sigridur Bjornsdottir(4), Maria Saaf(1), Sophie Bensing(1), Karl Michaelsson(2), Jonas F.Ludvigsson(3), (4)
(1)Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, (2)Department of Surgical Sciences, Section of Orthopaedics, SE-75185Uppsala University, (3)Clinical Epidemiology Unit, Karolinska Institutet, Karolinska University Hospital, (4)Department of Paediatric, Orebro University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S641-S641, 2010.

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P15-8-3 Marked changes in function of the hypothalamus-pituitary-adrenal(HPA)axis during lactation in rats

Ling mei Pan(1), Taeko Tomabechi(2), Gen Watanabe(1), (2), Kazuyoshi Taya(1), (2)
(1)Department of Basic Science, United Graduate School of Veterinary Sciences, Gifu University, (2)Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology
ENDOCRINE JOURNAL 57 (suppl.2-2) S641-S641, 2010.

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P15-8-4 Immunoreactivity against kidney collecting ducts in patients with autoimmune polyendocrine syndrome type 1 and systemic hypertension

Asa Hallgren(1), Mina Pourmousa(1), Jakob Skov(1), (2), Thomas Nilsson(1), Jan Gustafsson(3), Eystein S.Husebye(4), Jaakko Perheentupa(5), Eva Hagforsen(1), Fredrik Rorsman(1), Olle Kampe(1)
(1)Department of Medical Sciences, Uppsala University, (2)Present address:Department of Endocrinology and Diabetes, Karlstad Central Hospital, (3)Department of Women's and Children's health, Uppsala University, (4)Department of Medicine, Haukeland University Hospital, (5)Hospital for Children and Adolescents, Helsinki University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S641-S641, 2010.

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P15-8-5 Steroid profiles of the three adrenocortical zones in primary and secondary adrenal insufficiency

Toshihide Yamamoto
Yamamoto Naika Clinic
ENDOCRINE JOURNAL 57 (suppl.2-2) S641-S642, 2010.

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P15-8-6 Monitoring of replacement therapy in patients with Addison's disease, using salivary cortisol day curve measurements

Ian L.Ross(1), Naomi S.Levitt(1), Jan-Stefan Van der Walt(2), Tahir S.Pillay(3)
(1)Division of Endocrinology, University of Cape Town, (2)Division of Pharmacology, University of Cape Town, (3)Division of Chemical Pathology, University of Cape Town
ENDOCRINE JOURNAL 57 (suppl.2-2) S642-S642, 2010.

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P15-8-7 The consideration of external steroid therapy history and skin bruising sign with morning serum cortisol measurement predicts better results of rapid adrenocorticotropin stimulation test than morning serum cortisol only

Hyeong Jin Kim(1), Se Hwa Kim(1), Hyun Chul Lee(2)
(1)Division of Endocrinology, Department of Internal Medicine, Myongji Hospital, Kwandong University College of Medicine, (2)Division of Endocrinology, Department of Internal Medicine, Yonsei University College of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S642-S642, 2010.

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P15-8-8 Salivary and serum cortisol levels measured by liquid chromatography/tandem mass spectrometry reflect sexual function better than testosterone levels in middle-aged men

Yoshitomo Kobori, Ryo Sato, Yoshio Ashizawa, Hiroshi Yagi, Shigehiro Soh, Gaku Arai, Hiroshi Okada
Department of Urology, Dokkyo Medical University Koshigaya Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S642-S642, 2010.

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P15-9-1 Clinical features of bilateral adrenal tumors:Analysis of functioning tumors and metastatic tumors

Aki Ikoma, Masashi Yoshida, Tomoko Asano, Mizuho Kimoto, Miho Murata, Tomoyuki Saito, Hideo Toyoshima, Masafumi Kakei, Masanobu Kawakami, San-e Ishikawa
Jichi Medical University Saitama Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S642-S643, 2010.

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P15-9-2 Circadian rhythm of ACTH in X-linked adrenal hypoplasia congenita(AHC)

Rie Matusita(1), Yuichi Nakagawa(1), Akira Sakai(1), Eiko Nagata(1), Eiichiro Satake(1), Shinichiro Sano(1), Rie Yamaguchi(1), Yasuko Fujisawa(1), Toshiki Nakanishi(1), Takashi Nakano(2), Takehiko Ohzeki(1)
(1)Department of Pediatrics, Hamamatsu University School of Medicine, (2)Department of Pediatrics, National Mie Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S643-S643, 2010.

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P15-9-3 Transient congenital adrenal hyperplasia:Review of three cases

Belinda George, Ganapathi Bantwal, Vageesh Ayyar, R.Ananthraman, Madhuri Patil, Rohini Chandra
St.Johns Medical College Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S643-S643, 2010.

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P15-9-4 Change of adrenocortical hormones and lipids in Kawasaki disease

Shinichiro Sano, Yuichi Nakgawa, Satoru Iwashima, Takamichi Ishikawa, Eiichiro Satake, Rie Matsushita, Eiko Nagata, Rie Yamaguchi, Toshiki Nakanishi, Takehiko Ohzeki
Department of Pediatrics, Hamamatsu University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S643-S643, 2010.

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P15-9-5 Pregnancy outcome in women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency in PUMCH

Lin Lu, Zhengpei Zeng, Zhaolin Lu, Anli Tong, Shi Chen, Yonghui Wang, Chunli Fu
Department of Endocrinology, Peking Union Medical College Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S643-S643, 2010.

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P15-9-6 Phenotype-genotype correlation in 36 Chinese 17α-hydroxylase/17,20 lyase-deficiency patients with eight novel mutations of CYP17A1 gene

Min Nie, Lin Lu, Yuxiu Li, Lingling Xu, Ou Wang, Mingming Hu, Huijuan Zhu, Naishi Li, Yong Fu, Wenhui Li, Anli Tong, Tao Yuan, Weibo Xia, Xiaoping Xing, Zhaolin Lu
Key laboratory of Endocrine, Ministry of Health, Department of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences
ENDOCRINE JOURNAL 57 (suppl.2-2) S644-S644, 2010.

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P15-9-7 A case of rapidly manifested ACTH-dependent Cushing syndrome

Yasushi Miyazaki(1), Yukari Okamura(1), Osamu Matsushige(1), Hidehiro Someko(1), Akiyo Tanabe(2), Mika Tsuiki(2), Kazue Takano(2), Mitsuhide Naruse(3)
(1)Department of Internal Medicine, Misato Kenwa Hospital, (2)Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, (3)Kyoto Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S644-S644, 2010.

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P15-9-8 Effects of sugar cane extract(SCE)(Saccharum officinarum L.)on immune function and adrenal function

Sayed Z.Mobram(1), Ling mei Pan(1), (2), Toshikazu Kawai(3), Kenji Koge(3), Yoshikazu Hirota(4), Gen Watanabe(1), (2), Kazuyoshi Taya(1), (2)
(1)Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, (2)Department of Basic Veterinary Science, The Untied Graduate School of Veterinary Sciences, Gifu University, (3)Research Laboratory, Mitsui Sugar Co, Ltd, (4)Laboratory of Veterinary Hygiene, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology
ENDOCRINE JOURNAL 57 (suppl.2-2) S644-S644, 2010.

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P15-10-1 A case of subclinical Cushing's syndrome caused by aderenal incidentaloma with atypical appearance on CT

Senshu Hifumi(1), Tomoko Kimura(2), Isamu Miyamori(2), Yoshiji Miwa(3), Hideaki Itou(3)
(1)The Department of Internal Medicine, Kimura Hospital, (2)The Third Department of Internal Medicine, University of Fukui Faculty of Medical Science, (3)The Department of Urology, University of Fukui Faculty of Medical Science
ENDOCRINE JOURNAL 57 (suppl.2-2) S644-S645, 2010.

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P15-10-2 Comparison of the results of dexamethasone suppression test between RIA and LC-MS/MS

Tamiko Tamanah, Satoko Shimazu, Kazutaka Nanba, Hidenari Nomura, Takeshi Usui, Akira Shimatsu, Mitsuhide Naruse
Department of Endocrinology and Metabolism, National Hospital Organization Kyoto Medical Center
ENDOCRINE JOURNAL 57 (suppl.2-2) S645-S645, 2010.

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P15-10-3 Systemic effects of inhaled corticosteroids

Yoshie Kono, Kwijun Park, Masako Waki
Dep.of Internal Medicine, Div.of Endocrinology and Metabolism, Shizuoka City Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S645-S645, 2010.

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P15-10-4 The status of adrenal glands in different subtypes of aldosteronism

FeiYe(2), Zheng Y.Tang(2), Guang Ning(2)
(1)Chang Zheng Hospital, Second Military Medical University, (2)Shanghai Institute of Endocrine and Metabolic Diseases, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S645-S645, 2010.

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P15-10-5 Influences of obesity on hormonal data in patients with primary aldosteronism

Naohisa Tamura, Masakatsu Sone, Yasutomo Fukunaga, Daisuke Taura, Megumi Inuzuka, Takuhiro Sonoyama, Katsutoshi Kojima, Kyoko Honda, Misa Saijo, Masako Miura, Naotetsu Kanamoto, Akihiro Yasoda, Hiroshi Arai, Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S645-S645, 2010.

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P15-10-6 Aldosterone blockade improves visceral fat area in patients with primary aldosteronism

Shigehiro Karashima, Masashi Ohe, Mitsuhiro Kometani, Masashi Demura, Shunsuke Mori, Yasuhiro Yamamoto, Takashi Yoneda, Yoshiyu Takeda
Department of Internal Medicine, Graduate School of Medical Science, Kanazawa University
ENDOCRINE JOURNAL 57 (suppl.2-2) S646-S646, 2010.

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P15-10-7 Salt loading and inappropriate secretion of aldosterone contribute to the renal damage in angiotensin II overproducing mice

Maki Takeuchi, Miki Nagase, Shigeru Shibata, Shigetaka Yoshida, Wakako Kawarazaki, Kenichi Ishizawa, Toshiro Fujita
Department of Nephrology and Endocrinology, University of Tokyo Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S646-S646, 2010.

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P15-10-8 Effects of the blockade of angiotensin II and aldosterone on the experimental diabetic neuropathy

Yoshiyu Takeda, Hiroyuki Takata, Shigehiro Karashima, Mitsuhiro Kometani, Masashi Ohe, Masashi Demura, Shunsuke Mori, Yuan Cheng, Takashi Yoneda
Department of Internal Medicine, Graduate School of Medical Science, Kanazawa University
ENDOCRINE JOURNAL 57 (suppl.2-2) S646-S646, 2010.

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P15-11-1 Renal function deteriorates regardless of the type of treatments in primary aldosteronism

Mika Tsuiki(1), Akiyo Tanabe(1), Mitsuhide Naruse(2), Hitomi Kimura(1), Aya Tsumagari(1), Daisuke Watanabe(1), Sachiko Takagi(1), Kazue Takano(1)
(1)Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, (2)Division of Endocrinology, Clinical Research Institute of Endocrine and Metabolic Diseases, Kyoto Medical Center, National Hospital Organization
ENDOCRINE JOURNAL 57 (suppl.2-2) S646-S646, 2010.

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P15-11-2 Renal outcome in patients with primary aldosteronism:manifestation of "masked" CKD by correction of aldosterone-induced glomerular hyperfiltration and one-year follow-up with aldosterone blockade or unilateral adrenalectomy

Yoshitsugu Iwakura(1), Ryo Morimoto(1), Masataka Kudo(1), Osamu Murakami(1), Kei Takase(2), Shigeto Ishidoya(3), Yoichi Arai(3), (4), Hironobu Sasano(4), Hiroshi Sato(1), Fumitoshi Satoh(1), Sadayoshi Ito(1)
(1)Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Hospital, (2)Department of Diagnostic Radiology, Tohoku University Hospital, (3)Department of Urology, Tohoku University Hospital, (4)Department of Pathology, Tohoku University Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S647-S647, 2010.

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P15-11-3 Is adrenal venous sampling(AVS)required in primary aldosteronism with a single, unilateral adrenal nodule on CT?

Hitomi Kimura(1), Akiyo Tanabe(1), Mika Tsuiki(1), Aya Tsumagari(1), Ryohei Kuwatsuru(2), Mitsuhide Naruse(3), Kazue Takano(1)
(1)Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical Univercity, (2)Department of Radiology, Tokyo Women's Medical Univercity, (3)Division of Endocrinology, Clinical Research Institute of Endocrine and Metabolic Diseases Kyoto Medical Center, National Hospital Organization
ENDOCRINE JOURNAL 57 (suppl.2-2) S647-S647, 2010.

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P15-11-4 A case report of bilateral hyperaldosteronism with subclinical Cushing's syndrome, a possible glucocorticoid-remediable aldosteronism(GRA)

Kyoko Honda, Masakatsu Sone, Takuhiro Sonoyama, Naohisa Tamura, Yasutomo Fukunaga, Daisuke Taura, Megumi Inuzuka, Katsutoshi Kojima, Masako Miura, Naotetsu Kanamoto, Akihiro Yasoda, Hiroshi Arai, Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S647-S647, 2010.

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P15-11-5 Acute cerebral hemorrhage normalized plasma renin activity in a patient with primary aldosteronism

Tetsuya Hiraiwa(1), Ranko Ibata(1), Keiji Tanimoto(1), Naomune Yamamoto(1), Jungo Terasaki(1), Haruhito Azuma(2), Akihisa Imagawa(1), Toshiaki Hanafusa(1)
(1)First Department of Internal Medicine, Osaka Medical College, (2)Department of Urology, Osaka Medical College
ENDOCRINE JOURNAL 57 (suppl.2-2) S647-S647, 2010.

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P15-11-6 Adrenocorticotropic hormone receptor and adrenal tumors

Zhengpei Zeng(1), Wei Liang(1), Cai-Xia Cao(1), An-Ling Tong(1), Lin Lu(1), Shi Chen(1), Han-Zhong Li(2)
(1)Department of Endocrinology, Peking Union Medical College Hospital, (2)Dep.of Urology, Peking Union Medical College Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S648-S648, 2010.

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P15-11-7 Expression of steroidogenic factor-1 and DAX-1 in human adrenocortical tumors

Zhengpei Zeng(1), Cai-xia Cao(1), AnLi Tong(1), Lin Lu(1), Shi Chen(1), Han-Zhong Li(2)
(1)Department of Endocrinology, Peking Union Medical College Hospital, (2)Department of Urology, Urology, Peking Union Medical College Hospital
ENDOCRINE JOURNAL 57 (suppl.2-2) S648-S648, 2010.

全文ダウンロード：従量制、基本料金制の方共に121円(税込) です。

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P15-11-8 Vasopressin receptor and its pathophysiological roles in aldosterone-producing adenoma

Sawako Suzuki, Daigaku Uchida, Hisashi Koide, Keiko Suyama, Tomohiko Yoshida, Tomoaki Tanaka, Kotaro Yokote, Icihro Tatsuno
Clinical Cell Biology, Chiba University Graduate School of Medicine
ENDOCRINE JOURNAL 57 (suppl.2-2) S648-S648, 2010.

全文ダウンロード：従量制、基本料金制の方共に121円(税込) です。

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