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Biological and Pharmaceutical Bulletin 43巻 3号

発行元
日本薬学会
ISSN
0918-6158
ISSN(オンライン)
1347-5215

書籍情報から探す
開始頁
Current Topics Drug Discovery : Recent Progress and the Future Foreword
Akira Otaka
Institute of Biomedical Sciences and Graduate School of Pharmaceutical Sciences, Tokushima University
Biological and Pharmaceutical Bulletin 43 (3) 361-361, 2020.
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Drug Repositioning and Target Finding Based on Clinical Evidence
Shuji Kaneko, Takuya Nagashima
Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University
Biological and Pharmaceutical Bulletin 43 (3) 362-365, 2020.
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Selenoprotein P ; P for Plasma, Prognosis, Prophylaxis, and More
Ryouhei Tsutsumi, Yoshiro Saito
Laboratory of Metabolism and Molecular Biology, Graduate School of Pharmaceutical Sciences, Tohoku University
Biological and Pharmaceutical Bulletin 43 (3) 366-374, 2020.
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Reconstituted Human Organ Models as a Translational Tool for Human Organ Response : Definition, Expectations, Cases, and Strategies for Implementation in Drug Discovery and Development
Kazuhiro Tetsuka, Masato Ohbuchi, Tetsuhiro Kawabe, Takayuki Goto, Fumiko Kiyonaga, Kaori Takama, Shunji Yamazaki, Akira Fujimori
Astellas Pharma Inc.
Biological and Pharmaceutical Bulletin 43 (3) 375-383, 2020.
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Estimating Efflux Transporter-Mediated Disposition of Molecules beyond the Rule of Five (bRo5) Using Transporter Gene Knockout Rats
Taiji Miyake
Discovery ADMET Dept., Research Div., Chugai Pharmaceutical Co.,Ltd.
Biological and Pharmaceutical Bulletin 43 (3) 384-392, 2020.
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A Novel Binary Supercooled Liquid Formulation for Transdermal Drug Delivery
Yuya Hirakawa(a),(b), Hiroshi Ueda(a), Rie Wakabayashi(b), Noriho Kamiya(b),(c), Masahiro Goto(b),(d)
(a)Physicochemical and Preformulation, Applied Chemistry and Analysis, Research Laboratory for Development, Shionogi & Co.,Ltd., (b)Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, (c)Division of Biotechnology, Center for Future Chemistry, Kyushu University, (d)Center for Transdermal Drug Delivery, Kyushu University
Biological and Pharmaceutical Bulletin 43 (3) 393-398, 2020.
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Docetaxel Upregulates HMGB1 Levels in Non-small Cell Lung Cancer
Miya Haruna(a),(b), Michinari Hirata(a),(b), Kota Iwahori(b),(c), Takayuki Kanazawa(a), Yoko Yamamoto(b),(d), Kumiko Goto(a),(b), Atsunari Kawashima(e), Akiko Morimoto-Okazawa(b), Soichiro Funaki(d), Yasushi Shintani(d), Atsushi Kumanogoh(c), Hisashi Wada(b)
(a)Shionogi Co.,Ltd., (b)Department of Clinical Research in Tumor Immunology, Osaka University Graduate School of Medicine, (c)Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, (d)Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, (e)Department of Urology, Osaka University Graduate School of Medicine
Biological and Pharmaceutical Bulletin 43 (3) 399-403, 2020.
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Daily Meal Supplemented with Astaxanthin-Enriched Yolk Has Mitigative Effects against Hypertension in Spontaneously Hypertensive Rats
Toshimitsu Hatabu(a), Takumi Harada(a), Yuri Takao(a), Dung Ho Thi(a), Akihiro Yamasato(b), Tatsuya Horiuchi(b), Atsuya Mochizuki(b), Yasuhiro Kondo(a)
(a)Laboratory of Animal Physiology, Graduate School of Environmental and Life Science, Okayama University, (b)K.I Chemical Industry Co.,Ltd.
Biological and Pharmaceutical Bulletin 43 (3) 404-408, 2020.
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Neuroprotective Effects of Limonene (+) against Aβ42-Induced Neurotoxicity in a Drosophila Model of Alzheimer's Disease
Myeongcheol Shin(a), Quan Feng Liu(b),(c), Byoungyun Choi(a), Changmin Shin(a), Banseok Lee(a), Chunyu Yuan(a), You Jin Song(a), Hye Sup Yun(a), Im-Soon Lee(a), Byung-Soo Koo(b),(c), Kyoung Sang Cho(a)
(a)Department of Biological Sciences, Konkuk University, (b)Department of Oriental Medicine, Dongguk University, (c)Department of Oriental Neuropsychiatry, Graduate School of Oriental Medicine, Dongguk University
Biological and Pharmaceutical Bulletin 43 (3) 409-417, 2020.
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C-Terminal Cysteine PEGylation of Adalimumab Fab with an Engineered Interchain SS Bond
Hitomi Nakamura(a), Makoto Anraku(a), Naoko Oda-Ueda(a), Tadashi Ueda(b), Takatoshi Ohkuri(a)
(a)Faculty of Pharmaceutical Sciences, Sojo University, (b)Graduate School of Pharmaceutical Sciences, Kyushu University
Biological and Pharmaceutical Bulletin 43 (3) 418-423, 2020.
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Dexmedetomidine Protects SK-N-SH Nerve Cells from Oxidative Injury by Maintaining Iron Homeostasis
Lingqin Qiu, Li Ge, Qionghua Hu
Department of Anesthesiology Gansu People's Hospital
Biological and Pharmaceutical Bulletin 43 (3) 424-431, 2020.
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Extract of Salvia przewalskii Repair Tissue Damage in Chronic Hypoxia Maybe through the RhoA-ROCK Signalling Pathway
Yafeng Wang(a), Delong Duo(a), Yingjun Yan(a), Rongyue He(a), Shengbiao Wang(a), Aixia Wang(a), Xinan Wu(b)
(a)Department of pharmacy, Qinghai Provincial People's Hospital, (b)Department of pharmacy, The First Hospital of Lanzhou University
Biological and Pharmaceutical Bulletin 43 (3) 432-439, 2020.
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Anti-obesity Effect of Fermented Persimmon Extracts via Activation of AMP-Activated Protein Kinase
Minhyeok Song, Goowon Yang, Tran Quynh Hoa, Hoang Dang Hieu, Ain Syafiza Mohd Amin, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha
Department of Biochemistry and Molecular Biology, Graduate School, College of Medicine, Kyung Hee University
Biological and Pharmaceutical Bulletin 43 (3) 440-449, 2020.
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Resveratrol Attenuates Inflammatory Bowel Disease in Mice by Regulating SUMO1
Jingyan Wang(a), Zhaoyang Zhang(b), Anning Fang(c), Kehan Wu(a), Xiang Chen(d), Gaoying Wang(a), Fei Mao(a)
(a)Key Laboratory of Medical Science and Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University, (b)Taicang Hospital of Traditional Chinese Medicine, (c)Department of Basic Medicine, Anhui Medical College, (d)Zhenjiang Institute for Drug and Food Control
Biological and Pharmaceutical Bulletin 43 (3) 450-457, 2020.
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Risk Factors for Major Bleeding and Clinically Relevant Non-major Bleeding in Japanese Patients Treated with Edoxaban
Tomoki Takase(a), Hiroaki Ikesue(a), Haruna Nakagawa(a), Megumi Kinoshita(a), Nobuyuki Muroi(a), Takeshi Kitai(b), Yutaka Furukawa(b), Tohru Hashida(a)
(a)Department of Pharmacy, Kobe City Medical Center General Hospital, (b)Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital
Biological and Pharmaceutical Bulletin 43 (3) 458-462, 2020.
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Protective Effect of Saponins-Enriched Fraction of Gynostemma pentaphyllum against High Choline-Induced Vascular Endothelial Dysfunction and Hepatic Damage in Mice
Chengcheng Yang(a), Yan Zhao(a), Daoyuan Ren(b), Xingbin Yang(b)
(a)Key Laboratory of Ministry of Education for Medicinal Resource and Natural Pharmaceutical Chemistry, College of Life Sciences, Shaanxi Normal University, (b)Shaanxi Engineering Laboratory for Food Green Processing and Safety Control, and Key Laboratory of Ministry of Education for Medicinal Resource and Natural Pharmaceutical Chemistry
Biological and Pharmaceutical Bulletin 43 (3) 463-473, 2020.
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Determination of Intrinsic Creatine Transporter (Slc6a8) Activity and Creatine Transport Function of Leukocytes in Rats
Ayaka Taii(a), Masanori Tachikawa(a),(b), Yusuke Ohta(a), Ken-ichi Hosoya(c), Tetsuya Terasaki(a)
(a)Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, (b)Graduate School of Biomedical Sciences, Tokushima University, (c)Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
Biological and Pharmaceutical Bulletin 43 (3) 474-479, 2020.
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Gastrodin Inhibits H2O2-Induced Ferroptosis through Its Antioxidative Effect in Rat Glioma Cell Line C6
Ting Jiang(a),(b), Jun Chu(a), Hejuntao Chen(a),(b), Hui Cheng(a), Jingjing Su(a), Xuncui Wang(a), Yin Cao(a), Shasha Tian(c), Qinglin Li(a)
(a)Key Laboratory of Xin'an Medicine, Ministry of Education, Anhui University of Chinese Medicine, (b)School of Pharmacy, Anhui University of Chinese Medicine, (c)School of Pharmacy, Zhejiang Chinese Medical University
Biological and Pharmaceutical Bulletin 43 (3) 480-487, 2020.
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Increasing Diluent Volume Decreases Bendamustine-Induced Venous Irritation without Reducing the Therapeutic Efficacy
Shigeru Ishida(a), Hanae Morikawa(a), Hiroyuki Watanabe(a), Toshikazu Tsuji(a), Takeshi Sugio(b), Yasuo Mori(b), Toshihiro Miyamoto(b), Satohiro Masuda(a),(c), Koichi Akashi(b), Nobuaki Egashira(a)
(a)Department of Pharmacy, Kyushu University Hospital, (b)Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, (c)Department of Pharmacy, International University of Health and Welfare Narita Hospital
Biological and Pharmaceutical Bulletin 43 (3) 488-492, 2020.
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Effects of Catecholamine Metabolites on Beta-Adrenoceptor-Mediated Relaxation of Smooth Muscle : Evaluation in Mouse and Guinea-Pig Trachea and Rat Aorta
Fumiko Yamaki, Anna Koike, Hikari Kono, Xiaoyue Zhang, Kento Yoshioka, Keisuke Obara, Yoshio Tanaka
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University
Biological and Pharmaceutical Bulletin 43 (3) 493-502, 2020.
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Inhibitory Effects of Indirubin-3'-oxime Derivatives on Lipid Accumulation in 3T3-L1 Cells
Yasuhito Nobushi, Hiroaki Saito, Shinichi Miyairi, Taketo Uchiyama, Yukinaga Kishikawa
School of Pharmacy, Nihon University
Biological and Pharmaceutical Bulletin 43 (3) 503-508, 2020.
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Edaravone Protects against Pancreatic and Intestinal Injury after Acute Pancreatitis via Nuclear Factor-κB Signaling in Mice
Bingbin Wang, Wendong Lin
Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University
Biological and Pharmaceutical Bulletin 43 (3) 509-515, 2020.
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Involvement of A2B Receptor in DNA Damage Response and Radiosensitizing Effect of A2B Receptor Antagonists on Mouse B16 Melanoma
Yuta Tanaka(a), Kazuki Kitabatake(a), Ryo Abe(b),(c), Mitsutoshi Tsukimoto(a)
(a)Department of Radiation Biosciences, Faculty of Pharmaceutical Sciences, Tokyo University of Science, (b)Research Institute for Biomedical Sciences, Tokyo University of Science, (c)Strategic Innovation and Research Center, Teikyo University
Biological and Pharmaceutical Bulletin 43 (3) 516-525, 2020.
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WSF-7 Inhibits Obesity-Mediated PPARγ Phosphorylation and Improves Insulin Sensitivity in 3T3-L1 Adipocytes
Yudian Zhang(a), Yunyun Wang(b), Xiaochuan Li(a), Kerui Gu(a), Mingxin Li(b), Yan Zhang(b), Zhijie Zhang(c), Shifa Wang(b), Zhen Li(a)
(a)MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, (b)College of Chemical Engineering, Nanjing Forestry University, (c)Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
Biological and Pharmaceutical Bulletin 43 (3) 526-532, 2020.
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Kaempferol Protects Renal Fibrosis through Activating the BMP-7-Smad1/5 Signaling Pathway
Xiaojun Ji(a), Jing Cao(b), Liting Zhang(a), Zhirui Zhang(a), Weiwei Shuai(b), Wu Yin(a)
(a)State Key Lab of Pharmaceutical Biotechnology, College of Life Sciences, Nanjing University, (b)Department of Pharmacy, Women's Hospital of Nanjing Medical University (Nanjing Maternity and Child Health Care Hospital)
Biological and Pharmaceutical Bulletin 43 (3) 533-539, 2020.
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The Lysosome Pathway Degrades CD81 on the Cell Surface by Poly-ubiquitination and Clathrin-Mediated Endocytosis
Kohei Hosokawa, Hanako Ishimaru, Tadashi Watanabe, Masahiro Fujimuro
Department of Cell Biology, Kyoto Pharmaceutical University
Biological and Pharmaceutical Bulletin 43 (3) 540-545, 2020.
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Mitigation of Memory Impairment in Ovariectomized Rats Using Garlic Powder Treated with Subcritical Water
Akira Minami(a), Yasuyo Mikami(a), Takahiro Kano(a), Hiroshi Matsushita(b), Yuka Fujita(a), Marina Yoshimura(a), Yuki Abe(a), Hiromi Watanabe(c), Masaomi Hara(c), Yuki Kurebayashi(a), Tadanobu Takahashi(a), Hiroaki Kanazawa(d), Akihiko Wakatsuki(b), Takashi Suzuki(a)
(a)Department of Biochemistry, School of Pharmaceutical Sciences, (b)Department of Obstetrics and Gynecology, Aichi Medical University, School of Medicine, (c)Nikken Foods Co.,Ltd., (d)Department of Functional Anatomy, School of Nursing, University of Shizuoka
Biological and Pharmaceutical Bulletin 43 (3) 546-549, 2020.
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Equol Inhibits Mushroom Tyrosinase in Vitro through Tight Binding
Toshio Niwa(a), Haruna Akiyama(a), Madoka Echikawa(a), Shin-ichiro Yokoyama(b), Mika Mochizuki(c), Toshihiko Osawa(c)
(a)Faculty of Health and Nutrition, Shubun University, (b)Gifu Prefectural Research Institute for Food Sciences, (c)Department of Health and Nutrition, Faculty of Psychological & Physical Science, Aichi Gakuin University
Biological and Pharmaceutical Bulletin 43 (3) 550-553, 2020.
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The Effect of Liver Hydrolysate on Chronic Ethanol-Induced Hepatic Injury in Normal Rats
Kotaro Yamada(a), Kazuma Ueda(b), Hitoshi Shirakawa(b), Puspo Edi Giriwono(b),†, Satoru Honda(a), Hidetomo Sakurai(a), Michio Komai(b)
(a)Consumer Health Products Development, Zeria Pharmaceutical Co.,Ltd., (b)Laboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University, †Present address:Department of Food Science and Technology, Faculty of Agricultural Technology, IPB University
Biological and Pharmaceutical Bulletin 43 (3) 554-557, 2020.
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circACTR2 : A Novel Mechanism Regulating High Glucose-Induced Fibrosis in Renal Tubular Cells via Pyroptosis
Si Wen, Shuangliang Li, Lulu Li, Qiuling Fan
Department of Nephrology, First Hospital of China Medical University
Biological and Pharmaceutical Bulletin 43 (3) 558-564, 2020.
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Cholestyramine, a Bile Acid Sequestrant, Increases Cecal Short Chain Fatty Acids and Intestinal Immunoglobulin A in Mice
Saki Nishida, Ayumu Horinouchi, Yasuki Higashimura, Reina Akahori, Kenji Matsumoto
Department of Food Science, Ishikawa Prefectural University
Biological and Pharmaceutical Bulletin 43 (3) 565-568, 2020.
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Trimethylamine-N-oxide Specifically Impairs Endothelium-Derived Hyperpolarizing Factor-Type Relaxation in Rat Femoral Artery
Takayuki Matsumoto, Mihoka Kojima, Keisuke Takayanagi, Kumiko Taguchi, Tsuneo Kobayashi
Department of Physiology and Morphology, Institute of Medicinal Chemistry, Hoshi University
Biological and Pharmaceutical Bulletin 43 (3) 569-573, 2020.
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