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バックナンバー：Chemical and Pharmaceutical Bulletin

Chemical and Pharmaceutical Bulletin

63巻 12号

Importance of Proton-Coupled Electron Transfer from Natural Phenolic Compounds in Superoxide Scavenging

Tatsushi Nakayama, Bunji Uno
Gifu Pharmaceutical University
Chemical and Pharmaceutical Bulletin 63(12): 967-973, 2015.

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Synthesis and Anti-cancer Activity of Novel Thiazolidinone Analogs of 6-Aminoflavone

Sudheer Moorkoth†
Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal University, † Present address:Department of Pharmaceutical Quality Assurance, Manipal College of Pharmaceutical Sciences, Manipal University
Chemical and Pharmaceutical Bulletin 63(12): 974-985, 2015.

【アブストラクト】従量制は110円（税込）、基本料金制は基本料金に含まれます。
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Development and Assessment of a Nomogram to Propose the Initial Dosage Regimen of a Meropenem Infusion Based on Serum Creatinine and Age Using a Monte Carlo Simulation

Noriyuki Shino(a),(b), Takahiro Uchida(b), Miyako Yoshida(b), Yasuo Nomura(a)
(a)Pharmacy of Saiseikai Chuwa Hospital, (b)Department of Clinical Pharmaceutics, Mukogawa Women's University
Chemical and Pharmaceutical Bulletin 63(12): 986-991, 2015.

【アブストラクト】従量制は110円（税込）、基本料金制は基本料金に含まれます。
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Development of Novel Polymeric Prodrugs Synthesized by Mechanochemical Solid-State Copolymerization of Hydroxyethylcellulose and Vinyl Monomers

Naoki Doi(a), Yasushi Sasai(a), Yukinori Yamauchi(b), Tetsuo Adachi(c), Masayuki Kuzuya(d), Shin-ichi Kondo(a)
(a)Laboratory of Pharmaceutical Physical Chemistry, Gifu Pharmaceutical University, (b)Department of Pharmaceutical Physical Chemistry, Faculty of Pharmaceutical Sciences, Matsuyama University, (c)Laboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University, (d)Department of Health and Welfare, Faculty of Human Welfare, Chubu Gakuin University
Chemical and Pharmaceutical Bulletin 63(12): 992-997, 2015.

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Novel 2,7-Substituted (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acids : Peroxisome Proliferator-Activated Receptor γ Partial Agonists with Protein-Tyrosine Phosphatase 1B Inhibition

Kazuya Otake, Satoru Azukizawa, Shigemitsu Takeda, Masaki Fukui, Arisa Kawahara, Tatsuya Kitao, Hiroaki Shirahase
Drug Discovery Research Department, Kyoto Pharmaceutical Industries, Ltd.
Chemical and Pharmaceutical Bulletin 63(12): 998-1014, 2015.

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Discovery of Potent Antiproliferative Agents Targeting EGFR Tyrosine Kinase Based on the Pyrido [3',2':4,5] thieno [3,2-d] pyrimidin-4-amine Scaffold

Yasmine Mohamed Abdel Aziz(a), Mohamed Mokhtar Said(a), Hosam Ahmed El Shihawy(a), Mai Fathy Tolba(b), Khaled Abouzid Mohamed Abouzid(c)
(a)Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Suez Canal University, (b)Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, (c)Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University
Chemical and Pharmaceutical Bulletin 63(12): 1015-1028, 2015.

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Design, Synthesis, Biological Evaluation, and Antioxidant and Cytotoxic Activity of Heteroatom-Substituted 1,4-Naphtho- and Benzoquinones

Nahide Gulsah Deniz(a), Cemil Ibis(a), Zeliha Gokmen(a), Maryna Stasevych(b), Volodymyr Novikov(b), Olena Komarovska-Porokhnyavets(b), Mustafa Ozyurek(c), Kubilay Guclu(c), Didem Karakas(d), Engin Ulukaya(e)
(a)Division of Organic Chemistry, Department of Chemistry, Engineering Faculty, Istanbul University, (b)Institute of Chemistry and Chemical Technology, Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology, Lviv Polytechnic National University, (c)Division of Analytical Chemistry, Department of Chemistry, Engineering Faculty, Istanbul University, (d)Department of Biology, Faculty of Arts and Sciences, Uludag University, (e)Department of Clinical Biochemistry, Faculty of Medicine, Uludag University
Chemical and Pharmaceutical Bulletin 63(12): 1029-1039, 2015.

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Adsorption of As (III) from Aqueous Solutions by Novel Fe-Mg Type Hydrotalcite

Fumihiko Ogata(a), Naohito Kawasaki(a),(b)
(a)Faculty of Pharmacy, Kinki University, (b)Antiaging Center, Kinki University
Chemical and Pharmaceutical Bulletin 63(12): 1040-1046, 2015.

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Crotocascarins I-K : Crotofolane-Type Diterpenoids, Crotocascarin γ, Isocrotofolane Glucoside and Phenolic Glycoside from the Leaves of Croton cascarilloides

Susumu Kawakami(a), Katsuyoshi Matsunami(b), Hideaki Otsuka(a),(b), Masanori Inagaki(a), Yoshio Takeda(a), Masatoshi Kawahata(c), Kentaro Yamaguchi(c)
(a)Department of Natural Products Chemistry, Faculty of Pharmacy, Yasuda Women's University, (b)Department of Pharmacognosy, Graduate School of Biomedical and Health Sciences, Hiroshima University, (c)Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences, Tokushima Bunri University Kagawa Campus
Chemical and Pharmaceutical Bulletin 63(12): 1047-1054, 2015.

【アブストラクト】従量制は110円（税込）、基本料金制は基本料金に含まれます。
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Multicomponent Reactions of Acetoacetanilide Derivatives with Aromatic Aldehydes and Cyanomethylene Reagents to Produce 4H-Pyran and 1,4-Dihydropyridine Derivatives with Antitumor Activities

Rasha Abdallah Azzam(a), Rafat Milad Mohareb(b)
(a)Department of Chemistry, Faculty of Science, Helwan University, (b)Department of Chemistry, Faculty of Science, Cairo University
Chemical and Pharmaceutical Bulletin 63(12): 1055-1064, 2015.

【アブストラクト】従量制は110円（税込）、基本料金制は基本料金に含まれます。
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New Glabretal Triterpenes from the Immature Fruits of Poncirus trifoliata and Their Selective Cytotoxicity

Ae-Ran Choi(a), In-Kyoung Lee(b), E-Eum Woo(b), Jin-Won Kwon(a), Bong-Sik Yun(a), Hae-Ryong Park(a)
(a)Department of Food Science and Biotechnology, Kyungnam University, (b)Division of Biotechnology and Advanced Institute of Environment and Bioscience, Chonbuk National University
Chemical and Pharmaceutical Bulletin 63(12): 1065-1069, 2015.

【アブストラクト】従量制は110円（税込）、基本料金制は基本料金に含まれます。
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Investigation of Physicochemical Drug Properties to Prepare Fine Globular Granules Composed of Only Drug Substance in Fluidized Bed Rotor Granulation

Ryohei Mise(a), Yasunori Iwao(a), Shin-ichiro Kimura(b), Yukiko Osugi(a), Shuji Noguchi(a), Shigeru Itai(a)
(a)Department of Pharmaceutical Engineering, School of Pharmaceutical Sciences, University of Shizuoka, (b)Pharmaceutical Research & Development, Kissei Pharmaceutical Co.,Ltd.
Chemical and Pharmaceutical Bulletin 63(12): 1070-1075, 2015.

【アブストラクト】従量制は110円（税込）、基本料金制は基本料金に含まれます。
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Effect of Chaenomeles sinensis Extract on Choline Acetyltransferase Activity and Trimethyltin-Induced Learning and Memory Impairment in Mice

Yoon Kyung Kwon(a), Soo Jung Choi(b), Cho Rong Kim(b), Jae Kyeom Kim(c), Hye Kyung Kim(d), Jong Hun Choi(e), Sang-Wook Song(f), Chang-Ju Kim(g), Gwi Gun Park(h), Cheung-Seog Park(i), Dong-Hoon Shin(a)
(a)Department of Food and Biotechnology, Korea University, (b)Functional Food Research Center, Korea University, (c)Department of Food Science and Nutrition, University of Minnesota, (d)Department of Food and Biotechnology, Hanseo University, (e)Natural Way Co.,Ltd., (f)Department of Family Medicine, St.Vincent's Hospital, College of Medicine, The Catholic University of Korea, (g)Department of Physiology, Kyung Hee University, (h)Department of Food Science and Biotechnology, GaChon University, (i)Department of Microbiology, School of Medicine, Kyung Hee University
Chemical and Pharmaceutical Bulletin 63(12): 1076-1080, 2015.

【アブストラクト】従量制は110円（税込）、基本料金制は基本料金に含まれます。
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Further New Xenicanes from a Chinese Collection of the Brown Alga Dictyota plectens

Min Zhao(a), Shimiao Cheng(b), Weiping Yuan(a), Jianyong Dong(a), Kexin Huang(a), Zhongmin Sun(c), Pengcheng Yan(a)
(a)School of Pharmaceutical Sciences, Wenzhou Medical University, (b)The Fifth Affiliated Hospital, Wenzhou Medical University, (c)Institute of Oceanology, Chinese Academy of Sciences
Chemical and Pharmaceutical Bulletin 63(12): 1081-1086, 2015.

【アブストラクト】従量制は110円（税込）、基本料金制は基本料金に含まれます。
【全文ダウンロード(6.16MB)】従量制、基本料金制の方共に660円(税込) です。
New 2-Benzoxazolinone Derivatives with Cytotoxic Activities from the Roots of Acanthus ilicifolius

Dan Zhao(a),(b), Lijun Xie(c), Lei Yu(b), Ni An(a),(b), Wei Na(a), Feng Chen(a), Youbin Li(a), Yinfeng Tan(a), Xiaopo Zhang(a)
(a)School of Pharmaceutical Science, Hainan Medical University, (b)Research Center on Life Sciences and Environmental Sciences, Harbin University of Commerce, (c)Fujian Institute of Microbiology
Chemical and Pharmaceutical Bulletin 63(12): 1087-1090, 2015.

【アブストラクト】従量制は110円（税込）、基本料金制は基本料金に含まれます。
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発行元：: 日本薬学会
ISSN：: 0009-2363
ISSN（オンライン）：: 1347-5223

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バックナンバー：Chemical and Pharmaceutical Bulletin

Importance of Proton-Coupled Electron Transfer from Natural Phenolic Compounds in Superoxide Scavenging

Synthesis and Anti-cancer Activity of Novel Thiazolidinone Analogs of 6-Aminoflavone

Development and Assessment of a Nomogram to Propose the Initial Dosage Regimen of a Meropenem Infusion Based on Serum Creatinine and Age Using a Monte Carlo Simulation

Development of Novel Polymeric Prodrugs Synthesized by Mechanochemical Solid-State Copolymerization of Hydroxyethylcellulose and Vinyl Monomers

Novel 2,7-Substituted (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acids : Peroxisome Proliferator-Activated Receptor γ Partial Agonists with Protein-Tyrosine Phosphatase 1B Inhibition

Discovery of Potent Antiproliferative Agents Targeting EGFR Tyrosine Kinase Based on the Pyrido [3',2':4,5] thieno [3,2-d] pyrimidin-4-amine Scaffold

Design, Synthesis, Biological Evaluation, and Antioxidant and Cytotoxic Activity of Heteroatom-Substituted 1,4-Naphtho- and Benzoquinones

Adsorption of As (III) from Aqueous Solutions by Novel Fe-Mg Type Hydrotalcite

Crotocascarins I-K : Crotofolane-Type Diterpenoids, Crotocascarin γ, Isocrotofolane Glucoside and Phenolic Glycoside from the Leaves of Croton cascarilloides

Multicomponent Reactions of Acetoacetanilide Derivatives with Aromatic Aldehydes and Cyanomethylene Reagents to Produce 4H-Pyran and 1,4-Dihydropyridine Derivatives with Antitumor Activities

New Glabretal Triterpenes from the Immature Fruits of Poncirus trifoliata and Their Selective Cytotoxicity

Investigation of Physicochemical Drug Properties to Prepare Fine Globular Granules Composed of Only Drug Substance in Fluidized Bed Rotor Granulation

Effect of Chaenomeles sinensis Extract on Choline Acetyltransferase Activity and Trimethyltin-Induced Learning and Memory Impairment in Mice

Further New Xenicanes from a Chinese Collection of the Brown Alga Dictyota plectens

New 2-Benzoxazolinone Derivatives with Cytotoxic Activities from the Roots of Acanthus ilicifolius

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