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Alternatives to Animal Testing and Experimentation 28巻 suppl号

発行元
日本動物実験代替法学会
ISSN
1344-0411
ISSN（オンライン）
2185-4726
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開始頁
SL-1. Alternative Approach to Animal Experiments Using Cell and Tissue Engineering
Junji Fukuda
Faculty of Engineering, Yokohama National University
Alternatives to Animal Testing and Experimentation 28 (suppl) 84-84, 2023.
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SL-2. Most Rational but Long-Term Strategy to Eliminate Animal Experiments
Akihiro Hisaka
Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University
Alternatives to Animal Testing and Experimentation 28 (suppl) 84-84, 2023.
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EL. Understanding biostatistics : For individuals involved in research on alternatives to animal experiments
Takashi Sozu
Department of Information and Computer Technology, Faculty of Engineering, Tokyo University of Science
Alternatives to Animal Testing and Experimentation 28 (suppl) 85-85, 2023.
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S1-1. The Rise of European 3R Centres, their Network EU3Rnet and the COST Action Networking Activity IMPROVE
Winfried Neuhaus
EUSAAT-European Society of Alternatives to Animal Testing, Department of Medicine, Faculty of Medicine and Dentistry, Danube Private University, AIT Austrian Institute of Technology GmbH, Competence Unit Molecular Diagnostics
Alternatives to Animal Testing and Experimentation 28 (suppl) 86-86, 2023.
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S1-2. Developmental neurotoxicity of di-ethylhexyl phthalate in zebra fish larvaen
Sheikh Raisuddin1), Garima Jindal1), Padmshree Mudgal2)
1)Department of Medical Elementology & Toxicology, Jamia Hamdard (Hamdard University), 2)Department of Biochemistry, Daulat Ram College
Alternatives to Animal Testing and Experimentation 28 (suppl) 86-86, 2023.
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S1-3. Animal experiment reducing by rodent to organoid based approaches in accordance with the 3Rs principles
Sun-Hyun Park
R & D Center for Advanced Pharmaceuticals & Evaluation, Korea Institute of Toxicology
Alternatives to Animal Testing and Experimentation 28 (suppl) 87-87, 2023.
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S1-4. Toxicity assessment and mechanism of single and mixture exposure using stem cell assay
Wei Liu, Chenxi Wang, Yueming Lang, Hui Qin, Wei Cui, Minghan Li, Haiyang Luan
School of Environmental Science and Technology, Dalian University of Technology
Alternatives to Animal Testing and Experimentation 28 (suppl) 87-87, 2023.
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S1-5. Trends in legislation and education on animal welfare in Japan
Yoshie Kakuma
Teikyo University of Science
Alternatives to Animal Testing and Experimentation 28 (suppl) 88-88, 2023.
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S2-1. The Cutting Edge of Cultured Meat Research
Shoji Takeuchi
Dept. of Mechano-Informatics, Grad. Sch. of Information Science and Technology, The University of Tokyo / Institute of Industrial Science, The University of Tokyo
Alternatives to Animal Testing and Experimentation 28 (suppl) 89-89, 2023.
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S2-2. Development of DNA vaccines for COVID-19
Hiroki Hayashi
Department of Health Development and Medicine, Graduate School of Medicine, Osaka University
Alternatives to Animal Testing and Experimentation 28 (suppl) 89-89, 2023.
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S2-3. Utilization of alternative methods in a pharmaceutical industry
Yutaka Tonomura
Safety Research Dept., Discovery Research Labs., Nippon Shinyaku Co., Ltd.
Alternatives to Animal Testing and Experimentation 28 (suppl) 90-90, 2023.
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S2-4. Current status and issues of safety assessment using alternative methods in the Cosmetics Industry
Megumi Sakuma
KOSE Corporation R & D Laboratories
Alternatives to Animal Testing and Experimentation 28 (suppl) 90-90, 2023.
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S3-1. Next generation risk assessment of cosmetics using NAMs at The Japan Cosmetic Industry Association NGRA WG
Akemi Toyoda
Japan Cosmetic Industry Association NGRA WG / POLA chemical industries, Inc.
Alternatives to Animal Testing and Experimentation 28 (suppl) 91-91, 2023.
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S3-2. Utilization and future prospects of Threshold of Toxicological Concern (TTC) / Internal TTC for systemic toxicity evaluation of cosmetic ingredients
Shuichi Sekine
Brand Value R & D Institute, Shiseido Co., Ltd.
Alternatives to Animal Testing and Experimentation 28 (suppl) 91-91, 2023.
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S3-3. International collaborative research related to networks of Adverse Outcome Pathways (AOPs) in OECD etc
Shihori Tanabe
Division of Risk Assessment, Center for Biological Safety and Research, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 92-92, 2023.
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S3-4. Development of an objective read - across methodology for evaluating repeated - dose toxicity and Carcinogenicity
Kouichi Yoshinari
School of Pharmaceutical Sciences, University of Shizuoka
Alternatives to Animal Testing and Experimentation 28 (suppl) 92-92, 2023.
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S4-1. Development status and prospects of alternatives to animal testing for medical devices
Eiichi Yamamoto
Division of Medical Devices, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 93-93, 2023.
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S4-2. Current international status of the alternative methods to animal tests for irritation testing using reconstructed human epidermis for Medical devices
Reiko Kato
Division of Medical Devices, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 93-93, 2023.
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S4-3. Development of alternative methods for skin sensitization animal tests
Atsuko Miyajima
Division of Medical Devices, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 94-94, 2023.
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S4-4. Development of positive reference materials for in vivo and in vitro sensitization testing
Yusuke Nomura
National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 94-94, 2023.
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S4-5. Alternatives to animal experiments with chemical analysis
Yusuke Okamoto
Division of Medical Devices, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 95-95, 2023.
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S4-6. Current activities of international standardization on alternative test method for biological evaluation of medical devices
Ryusuke Nakaoka
Division of Medical Devices, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 95-95, 2023.
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S5-1. Evolution of drug discovery for infectious diseases by utilizing MPS technology
Kazuo Takayama
Center for iPS Cell Research and Application, Kyoto University
Alternatives to Animal Testing and Experimentation 28 (suppl) 96-96, 2023.
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S5-2. A general-purpose micro-physiological system : Gravity-driven and electric-assisted micro-uidic culture for human induced pluripotent stem cell assays
Kiyoshi Ohnuma
Department of Materials Science and Bioengineering, Nagaoka University of Technology
Alternatives to Animal Testing and Experimentation 28 (suppl) 96-96, 2023.
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S5-3. (English title not announced)
Shinji Sakai
Graduate School of Engineering Science, Osaka University
Alternatives to Animal Testing and Experimentation 28 (suppl) 97-97, 2023.
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S5-4. Manipulation and Assessment of Biological Phenomena in Three-dimensional Culture Models via Engineered Vascular Networks
Yuji Nashimoto
Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental Unversity
Alternatives to Animal Testing and Experimentation 28 (suppl) 97-97, 2023.
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S5-5. Microphysiological Systems Based on Micro-uidics for Commercialization
Hiroshi Kimura
Micro / Nano Technology Center, Tokai University
Alternatives to Animal Testing and Experimentation 28 (suppl) 98-98, 2023.
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S6-1. Safety evaluation with no-animal test methods for food additives
Hajime Kojima
Div. of Food Additives, National Insititute of Health Sciences (NIHS)
Alternatives to Animal Testing and Experimentation 28 (suppl) 99-99, 2023.
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S6-2. ILSI Japan : Approaches to predict internal exposure for food safety and functionality assessment
Takuya Kikuchi
International Life Sciences Institute (ILSI) Japan
Alternatives to Animal Testing and Experimentation 28 (suppl) 99-99, 2023.
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S6-3. Utilization of human induced pluripotent stem cell - derived small intestinal epithelial cells for precise prediction of internal exposure of functional food compounds
Shunta Shigemura
Researcher, Safety Science Research, Kao Corporation
Alternatives to Animal Testing and Experimentation 28 (suppl) 100-100, 2023.
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S6-4. Development of the experimental systems with human cryptderived intestinal cells for the prediction of intestinal drug absorption and drug-induced intestinal toxicity
Kazuya Maeda
School of Pharmacy, Kitasato University
Alternatives to Animal Testing and Experimentation 28 (suppl) 100-100, 2023.
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S6-5. Development of evaluation system for central nervous system action potential of food ingredients using human-induced pluripotent stem cell-derived neural stem cells
Yuki Hanafusa
Suntory Holdings Limited
Alternatives to Animal Testing and Experimentation 28 (suppl) 101-101, 2023.
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S7-1. Evaluation of the eye irritation by in vitro test for the application of quasi-drugs
Takayuki Abo
Kao Corporation, Safety Science Research
Alternatives to Animal Testing and Experimentation 28 (suppl) 102-102, 2023.
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S7-2. Development of an alternative oral mucosal irritation test : a proposal to the approval procedure of quasi-drugs
Seiya Aizawa
LION Corporation, Safety Science Research Laboratories
Alternatives to Animal Testing and Experimentation 28 (suppl) 102-102, 2023.
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S7-3. Skin sensitization evaluation using the alternative method for animal experiment in the quasi-drug application - Current status, issues, and future prospects
Morihiko Hirota
Shiseido Brand Value R & D Institute
Alternatives to Animal Testing and Experimentation 28 (suppl) 103-103, 2023.
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S7-4. Current situation of in vitro skin irritation evaluation for quasi-drugs application and towards expanding the applicability domain
Hidefumi Ikeda
Mandom Corporation
Alternatives to Animal Testing and Experimentation 28 (suppl) 103-103, 2023.
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S8-1. Analysis of thyroid hormone action on the development of the central nervous system
Noriyuki Koibuchi
Department of Integrative Physiology, Gunma University Graduate School of Medicine
Alternatives to Animal Testing and Experimentation 28 (suppl) 104-104, 2023.
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S8-2. Current regulatory status of evaluation for thyroid disruptors and our research efforts using an short-term study, "Thyroid Comparative Assay" in rats
Tomoya Yamada
Environmental Health Science Laboratory, Sumitomo Chemical Company, Ltd.
Alternatives to Animal Testing and Experimentation 28 (suppl) 104-104, 2023.
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S8-3. Developmental neurotoxicity assessment of chemicals and our efforts to assess thyroid hormones
Yasunari Kanda
Division of Pharmacology, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 105-105, 2023.
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S8-4. Assessment of thyroid hormone system mechanistically relevant test methods, towards integration into an IATA
Miriam N Jacobs, Dries Knapen, Ingrid Langezaal
UK Health Security Agency, University of Antwerp, EURL ECVAM
Alternatives to Animal Testing and Experimentation 28 (suppl) 105-105, 2023.
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S9-1. Drug screening system using cell ber technology
Midori Kato - Negishi
Department of Bio-Analytical Chemistry, Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Musashino University
Alternatives to Animal Testing and Experimentation 28 (suppl) 106-106, 2023.
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S9-2. Construction and Application of Cultured Tissues with Human Autonomic Neurons
Yuzo Takayama
Cellular and Molecular Biotechnology Institute, National Institute of Advanced Industrial Science and Technology (AIST)
Alternatives to Animal Testing and Experimentation 28 (suppl) 106-106, 2023.
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S9-3. Study for drug-induced seizure prediction using cultured neurons and microelectrode array system
Aoi Odawara
Advanced Biosignal Safety Assessment, Eisai Co., Ltd.
Alternatives to Animal Testing and Experimentation 28 (suppl) 107-107, 2023.
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S9-4. Expectations and challenges of in vitro BBB models for drug discovery and development targeting the central nervous system
Shinji Iwasaki
Takeda Pharmaceutical Company Limited, Drug Metabolism and Pharmacokinetics Research Laboratories
Alternatives to Animal Testing and Experimentation 28 (suppl) 107-107, 2023.
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S9-5. Neural Organoids as Alternatives for Animal Models
Yoshiho Ikeuchi
Institute of Industrial Science, The University of Tokyo
Alternatives to Animal Testing and Experimentation 28 (suppl) 108-108, 2023.
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A-1. The development of the IL-2 Luc assay (OECD444A)
Yutaka Kimura
Kimura Dermatology Clinic
Alternatives to Animal Testing and Experimentation 28 (suppl) 109-109, 2023.
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A-2. Development of in vitro skin irritation test for cosmetic ingredients
Mariko Sugiyama
Business Core Technology Center, Shiseido Co., Ltd.
Alternatives to Animal Testing and Experimentation 28 (suppl) 109-109, 2023.
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M-0. Mandom International Research Grants on Alternative to Animal Experiments
Japanese Society for Alternative to Animal Experiments

Alternatives to Animal Testing and Experimentation 28 (suppl) 110-110, 2023.
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M-1. Evaluation of effects of tumor microenvironment on cancer metastasis using microphysiological systems
Japanese Society for Alternative to Animal Experiments

Alternatives to Animal Testing and Experimentation 28 (suppl) 110-110, 2023.
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M-2. Reproduction of Drug Resistance in Pancreatic Cancer Cells using 3D Culture Carrier
Yuji Komizu
Division of Applied Life Science, Graduate School of Engineering, Sojo University
Alternatives to Animal Testing and Experimentation 28 (suppl) 111-111, 2023.
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P-01. Neutrophilic in-ammation by PM2.5 exposure to the 3D epidermis and screening of plant extracts to suppress epidermis impac
Yasuhiro Ishihara1), Maori Kono2)3), Tomoaki Okuda4)
1)Graduate School of Integrated Sciences for Life, Hiroshima University, 2)Graduate School of Pharmaceutical Sciences, Osaka University, 3)Mandom Corporation, 4)Faculty of Science and Technology, Keio University
Alternatives to Animal Testing and Experimentation 28 (suppl) 113-113, 2023.
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P-02. Investigation of test methods for predicting primary skin irritation due to cosmetic ingredients and / or formulations
Hiroki Aoike
Basic Research Center, Takara Belmont Corporation
Alternatives to Animal Testing and Experimentation 28 (suppl) 113-113, 2023.
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P-03. Development of a method for predicting human patch test results using Hansen solubility parameters
Aika Kishimoto, Nobuyuki Fujiwara, Koji Toyoda, Len Ito, Yuuki Sakurai
Milbon Co., Ltd. Research and Development Department
Alternatives to Animal Testing and Experimentation 28 (suppl) 114-114, 2023.
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P-04. Effects of plant components on human skin and human commensal bacteria
Yumi Motoyama1), Naoki Soga1), Masakazu Ito1), Saeko Nakajima3), Ichiro Nakagawa3), Akinori Ikeuchi1)2)
1)Frontier Research Center, Toyota motor corporation, 2)TOYOTA CENTRAL R & D LABS., INC, 3)Kyoto university Graduate School of Medicine
Alternatives to Animal Testing and Experimentation 28 (suppl) 114-114, 2023.
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P-05. Development of a novel melanocytecontaining 3D skin model toward evaluation of the functionality of skin lightening cosmetics
Katsunari Tezuka, Hiroaki Shichiri, Yaling Li, Yuko Sakurai
Skinscience Laboratory, Ands Corporation K.K
Alternatives to Animal Testing and Experimentation 28 (suppl) 115-115, 2023.
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P-06. Construction of a system for expressing and purifying human recombinant proteins using HEK293 cells and its application
Norie Hamaguchi1)2)3), Naohiko Anzai2), Satoshi Ogasawara3), Takeshi Murata3)
1)Graduate School of Medical and Pharmaceutical Sciences, Chiba University, 2)Pharmacology, Graduate School of Medicine, Chiba University, 3)Biostructural chemistry, Graduate school of science, Chiba University
Alternatives to Animal Testing and Experimentation 28 (suppl) 115-115, 2023.
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P-07. Introduction of the Iberian ribbed newt, a new model animal for urodele amphibians
Toshinori Hayashi1)2), Kazuko Okamoto1)2), Testuya Ohbayashi3), Takashi Takeuchi3)
1)Hiroshima University Amphibian Research Center, 2)Graduate School of Integrated Sciences for Life, Hiroshima University, 3)Faculty of Medicine, Tottori University
Alternatives to Animal Testing and Experimentation 28 (suppl) 116-116, 2023.
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P-08. Development of a developmental toxicity test using the Iberian ribbed newt Pleurodeles waltl
Tetsuya Ohbayashi1), Akiko Adachi1), Hiroshi Ohnishi1), Toshinori Hayashi2), Masaharu Akita3)
1)Organization for Research Initiative and Promotion, Tottori - University, 2)Amphibian Research Center, Hiroshima University, 3)Department of Nutrition and Dietetics, Kamakura Women's Univ
Alternatives to Animal Testing and Experimentation 28 (suppl) 116-116, 2023.
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P-09. Examination of some factors affecting in vitro pyrogen test
Kazuto Narita1), Miwako Kobayashi1), Asuka Sato1), Shigehiro Tachibana1), Hajime Kojima1)2)
1)Food and Drug Safety Center, Hatano Research Institute, 2)National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 117-117, 2023.
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P-10. A well-of-the-well based cell culture device with electrochemical sensors for on-site sensitive biomonitoring systems
Yuma Hori1), Laner Chen2), Hiroshi Kimura2), Kikuo Komori1)
1)Kindai University, 2)Tokai University
Alternatives to Animal Testing and Experimentation 28 (suppl) 117-117, 2023.
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P-11. PXB-cells LA : primary human hepatocytes with NAFLD-like properties
Masaki Takahashi1), Keishi Hata2), Sayaka Tomatsu2), Mutsumi Inamatsu1), Nami Yoshikawa1), Masakazu Kakuni1)
1)Phoenix Bio Co. Ltd, 2)Akita research institute of food and brewing
Alternatives to Animal Testing and Experimentation 28 (suppl) 118-118, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-12. An in vitro alveolar epithelial model controlled by the growth and differentiation of primary human alveolar epithelial cells
Ikuya Tanabe1), Miki Igarashi2), Shinkichi Ishikawa1), Kousuke Inamura2), Danoy Mathieu2), Choi Hyunjin2), Masaki Nishikawa2), Yasuyuki Sakai2)
1)Scientific Product Assessment Center, R & D Group, Japan Tobacco Inc., 2)Department of Chemical System Engineering, Graduate School of Engineering, University of Tokyo
Alternatives to Animal Testing and Experimentation 28 (suppl) 118-118, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-13. Differentiation of cardiomyocyte aggregates derived from hiPS spheroids - combining 3D rotational suspension culture system and physically spheroids fragmentation method - ture system and physically spheroids fragmentation method
Yo Uemura1), Tsubasa Matsui1)2), Takahiro Ono1), Toshimasa Uemura1)2), Masao Sasai3), Nagako Sougawa3), Shigeru Miyagawa3), Masahiro Kinooka4), Kenichi Morita1), Takashi Tsumura1)
1)JTEC CORPORATION, 2)Osaka University - Riken Ctr. Sci. Tech., 3)Grad. Sch. Med., Osaka Univ., 4)Dept. Biotech., Grad. Sch. Eng., Osaka Univ.
Alternatives to Animal Testing and Experimentation 28 (suppl) 119-119, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-14. Characterization of reactive human immortalized astrocytes, HASTR / ci35
Momoka Takasaki, Yuka Negishi, Riho Hasegawa, Syun Nagashima, Tomoyo Baba, Hanae Morio, Tomomi Furihata
Tokyo University of Pharmacy and Life Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 119-119, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-15. RhE-based testing strategy (RTS) dened approach for skin sensitization potential identication and potency categorization using EpiSensA and in silico data
Sho Suzuki1), Hideyuki Mizumachi1), Megumi Sakuma2), Midori Natsui1), Takuo Yuki1), Noriyasu Imai2), Masaaki Miyazawa1)
1)Kao Corporation, 2)KOSE Corporation
Alternatives to Animal Testing and Experimentation 28 (suppl) 120-120, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-16. Case study of skin sensitization risk assessment by NGRA using EpiSensA
Hideyuki Mizumachi, Sho Suzuki, Takuo Yuki, Masaaki Miyazawa
Safety Science Research, Kao Corporation
Alternatives to Animal Testing and Experimentation 28 (suppl) 120-120, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-17. Effects of storage of LabCyte EPI-MODEL24, the reconstructed human epidermis, on the in vitro skin sensitization assay EpiSensA
Sachiko Fujiwara
Japan Tissue Engineering Co., Ltd.
Alternatives to Animal Testing and Experimentation 28 (suppl) 121-121, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-18. Skin sensitization ADRA test using liquid chromatograph mass spectrometer (LC-MS)
Ayako Nomura, Manami Kobayashi
Solutions Center of Excellence, Shimadzu Corporation
Alternatives to Animal Testing and Experimentation 28 (suppl) 121-121, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-19. Investigation of other suitable positive controls in h-CLAT
Kanako Nakayama1), Shiho Oeda2), Taku Nishijo1), Hideyuki Mizumachi1), Morihiko Hirota2), Akiko Tamura2), Masaaki Miyazawa1)
1)Safety Science Research Laboratories, Kao Corporation, 2)Brand Value R & D Institute, Shiseido Co., Ltd.
Alternatives to Animal Testing and Experimentation 28 (suppl) 122-122, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-20. Construction of rapid sensitization assessment by improvement of the chromophore solid phase peptide reaction assay (C-SPRA)
Fumihiro Kayamori1), Minami Maeda1), Masae Fukuda1), Hideto Ariumi2), Yoshio Hamada1), Kenji Usui1)
1)Faculty of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, 2)Faculty of Pharmaceutical Sciences, Sanyo - Onoda City University
Alternatives to Animal Testing and Experimentation 28 (suppl) 122-122, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-21. Development of an improved 2-step DC/T coculture system by applying Th2 cell lines to discriminate between respiratory and skin sensitizers
Izuru Mizoguchi, Yasuhiro Katahira, Hidenori Hasegawa, Aruma Watanabe, Ami Sekine, Jukito Sonoda, Miu Yamagishi, Takayuki Yoshimoto
Department of Immunoregulation, Institute of Medical Science, Tokyo Medical University
Alternatives to Animal Testing and Experimentation 28 (suppl) 123-123, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-22. Evaluation of the detectability of trace skin sensitizers in mixtures by Cation Adduct Detection Assay
Masataka Kitadani1), Yohei Shimizu1), Hideyuki Mizumachi2), Takuo Yuki2), Akihiro Moriuchi1), Ryou Koike1)
1)Kao Corporation, R & D - Analytical Science Research, 2)Kao Corporation, R & D - Safety Science Research
Alternatives to Animal Testing and Experimentation 28 (suppl) 123-123, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-23. Evaluation of adducts of nucleophiles and trace skin sensitizers by Cation Adduct Detection Assay (CADA)
Yohei Shimizu1), Masataka Kitadani1), Hideyuki Mizumachi2), Takuo Yuki2), Akihiro Moriuchi1), Ryou Koike1)
1)Kao Corporation, R & D - Analytical Science Research, 2)Kao Corporation, R & D - Safety Science Research
Alternatives to Animal Testing and Experimentation 28 (suppl) 124-124, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-24. Additional research on the gravimetric approach of the DPRA test method
Mutsumi Kobayashi1), Hiromi Katoh1), Shigehiro Tachibana1), Hajime Kojima1)2)
1)Hatano Research Institute, Food and Drug Safety Center, 2)National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 124-124, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-25. Application of dened approaches for skin sensitization and dermal sensitization thresholds in skin sensitization risk assessment of mixture ingredients : Case studies with botanical extracts
Taku Nishijo1)9), Satoru Miyazawa2)9), Makoto Mizuno2)9), Shiho Oeda3)9), Takumi Nukaga3)9), Noriki Iwai4)9), Yoshinao Kato4)9), Yuko Arita5)9), Ayumi Kimura5)9), Toshihiko Kasahara6)9), Yusuke Yamamoto6)9), Sayaka Wanibuchi6)9), Kota Hatano7)9), Ryo Koizumi8)9), Shinichi Watanabe8)9), Morihiko Hirota3)9)
1)Safety Science Research Laboratories, Kao Corporation, 2)Safety and Analytical Research Laboratories, KOSE Corporation, 3)Brand Value R & D Institute, Shiseido Co., Ltd., 4)Research Laboratories, Nippon Menard Cosmetic Co., Ltd., 5)Safety Research Laboratories, Pias Corporation, 6)Safety Evaluation Center, FUJIFILM Corporation, 7)General Research & Development Institute, Hoyu Co., Ltd., 8)Safety Science Research Laboratories, LION Corporation, 9)Task Force for Skin Sensitization Assessment of Mixture, Japan Cosmetic Industry Association
Alternatives to Animal Testing and Experimentation 28 (suppl) 125-125, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-26. Failure of acceptance criteria and its countermeasure in the ROS assay (OECD TG No.495)
Toshiyuki Ohtake, Morihiko Hirota
Brand Value R & D Institute, Shiseido Co., Ltd.
Alternatives to Animal Testing and Experimentation 28 (suppl) 125-125, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-27. Development of a novel in vitro phototoxicity test method using human ES/iPS cells-derived retinal pigment epithelial cells for evaluation of UVB absorbers
Ryota Kobayashi, Ryoko Matsuyama, Sachiko Kitamoto, Hiroyuki Asano
Environmental Health Science Laboratory, Sumitomo Chemical Co. Ltd.
Alternatives to Animal Testing and Experimentation 28 (suppl) 126-126, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-28. Modied ESR based photosafety test (ESR-PT) detecting singlet oxygen and free radical formation
Masumi Hinoshita1), Takayuki Abe2), Yosuke Maeda3), Masahiro Takeyoshi3)
1)CERI Osaka, Chemicals Evaluation and Research Institute, 2)CERI Tokyo, Chemicals Evaluation and Research Institute, 3)Chemicals Assessment and Research Center, Chemicals Evaluation and Research Institute
Alternatives to Animal Testing and Experimentation 28 (suppl) 126-126, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-29. Examination of internal Threshold of Toxicological Concern (iTTC) using human clinical data for non-animal Systemic toxicity assessment
Toshihide Takeshita, Yuuko Nukada, Shouta Nakagawa, Shinpei Terasaka
Safety Science Research Laboratories, Kao Corporation
Alternatives to Animal Testing and Experimentation 28 (suppl) 127-127, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-30. Introduction of internal TTC setting and case studies for evaluation of developmental toxicity of cosmetic ingredients
Shuichi Sekine, Tomoka Hisaki, Takumi Nukaga
Brand Value R & D Institute, Shiseido Co., Ltd
Alternatives to Animal Testing and Experimentation 28 (suppl) 127-127, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-31. Enrichment Analysis of Plasma Protein Attachment Characteristics and Cellular Dynamics Assessment Using THP-1 Macrophages for Predicting the Long-Term Effects of Microplastics
Shohei Kaneko1), Hyun jin Choi1), Masaki Nishikawa1), Hiroyuki Kusuhara2), Yasuyuki Sakai1)
1)Department of Chemical System Engineering, Graduate School of Engineering, University of Tokyo, 2)Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, the University of Tokyo
Alternatives to Animal Testing and Experimentation 28 (suppl) 128-128, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-32. Prediction of Plasma Concentration from In Vitro Release Test by Wagner - Nelson Method - Case study with ketoprofen patches
Motohiro Kato
DMPK academy
Alternatives to Animal Testing and Experimentation 28 (suppl) 128-128, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-33. Functional analysis of small intestinal epithelial cells derived from human induced pluripotent stem cells and usefulness as an in vitro human intestinal model
Yasushi Morohashi
Bio Science & Engineering Laboratory, FUJIFILM Corporation
Alternatives to Animal Testing and Experimentation 28 (suppl) 129-129, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-34. An Articial Mucus Barrier Involved in vitro Model that can Recapitulate the Long-term Host microbe Interaction Between Various Types of Gut Microbiota and Epithelial Caco-2 cells
Wenxin Cao, Hyunjin Choi, Masaki Nishikawa, Yasuyuki Sakai
Department of Chemical System Engineering, Graduate School of Engineering, University of Tokyo
Alternatives to Animal Testing and Experimentation 28 (suppl) 129-129, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-35. Preparation of uniform celluler aggregates using three-dimensional culture plate composed of the chemically synthesized polymer, HYDROX(TM)
Yuki Okumura, Junko Enomoto, Haruka Yamazaki, Masaki Kanai
Technology Research Laboratory, Shimadzu Corporation
Alternatives to Animal Testing and Experimentation 28 (suppl) 130-130, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-36. Automated Investigation of Spheroid Generation Using Methylcellulose Medium
Kouta Yamamoto1), Yoshihiko Watanabe2)3), Nobuhiko Kojima2)3)
1)NSK Ltd., 2)Ecocell Co., Ltd., 3)Yokohama City University
Alternatives to Animal Testing and Experimentation 28 (suppl) 130-130, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-37. Formation of vascular structure in in vitro liver model with bile canaliculi formation and high metabolic function
Kouichi Hattori1)2)
1)Toppan Inc, 2)Graduate School of Engineering Osaka University
Alternatives to Animal Testing and Experimentation 28 (suppl) 131-131, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-38. Organ-on-a-Chip system for assessment of chronic bronchities : Bronchus-on-a-Chip
Akina Mori1), Bart Kramer2), Marjolein Vermeer2), Lenie J.van den Broek2), Jeroen Heijmans2), Arnaud Nicolas2), Josse Bouwhuis2), Thanasis Giannitsis2), Todd Burton2), Kazushi Matsumura1), Kazuhiro Ohasi1), Shigeaki Ito1)
1)Japan Tobacco Inc. Scientific Product Assessment Center, 2)Mimetas BV
Alternatives to Animal Testing and Experimentation 28 (suppl) 131-131, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-39. Development of insert column type vascular network MPS
Takeshi Hori1), Moe Ando2), Akane Yamamoto1), Isamu Kitano3), Kohei Ishihara3), Taro Mizuta3), Shotaro Yoshida2), Yuji Nashimoto1), Hirokazu Kaji1)
1)Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2)Faculty of Science and Engineering, Chuo University, 3)Mizuta Seisakusho, Inc.
Alternatives to Animal Testing and Experimentation 28 (suppl) 132-132, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-40. Development of automatic - oating culture system using gas permeable syringe vessel for hiPSCs mass Culture
Toshimasa Uemura1)2), Takuya Hikoe2), Meihua Jin2), Yo Uemura2), Akari Nishida2), Tsubasa Matsui1)2), Kenichi Morita2), Takahiro Ono2), Takashi Tsumura2)
1)Osaka University - Riken Center for Science and Technology, Osaka University, 2)JTEC CORPORATION
Alternatives to Animal Testing and Experimentation 28 (suppl) 132-132, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-41. Development of shear stress culture system for vascular endothelial cells using a pressure driven microphysiological system
Shinji Sugiura1), Tatsunosuke Tomita1), Kazuma Kurihara2), Chikara Miyake3), Tomoki Ohkubo3), Yoichi Fujiyama3), Masaki Kanai3)
1)Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 2)Advanced Manufacturing Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 3)Technology Research Laboratory, Shimadzu Corporation
Alternatives to Animal Testing and Experimentation 28 (suppl) 133-133, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-42. Basic study for the development of in vitro assays to elucidate the pathogenesis of non alcoholic hepatitis
Seiichi Ishida1)2), Yukie Kuroda2), Shinichiro Horiuchi2), Kotaro Aoi1), Satoha Aihoshi1), Hiroyoshi Sadohara1), Yuji Komizu1), Taku Matsushita1)
1)Division of Applied Life Science, Graduate School of Engineering, Sojo University, 2)Division of Pharmacology, National Institute of Health Science
Alternatives to Animal Testing and Experimentation 28 (suppl) 133-133, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-43. Recapitulation of the formation process of human small intestinal tissue utilizing iPS cells and organ-on-a-chip technology
Sayaka Deguchi1), Fuki Yokoi1), Ryosuke Negoro2), Yukio Watanabe1), Mio Iwasaki1), May Koyama1), Takuya Yamamoto1), Yusuke Torisawa3), Kazuo Takayama1)4)
1)Center for iPS Cell Research and Application, Kyoto University, 2)College of Pharmaceutical Sciences, Ritsumeikan University, 3)Department of Micro Engineering, Kyoto University, 4)AMED - CREST
Alternatives to Animal Testing and Experimentation 28 (suppl) 134-134, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-44. Development of a linkable biomimetic system capable of simulating multi-organ cell interactions
Takeo Shimasaki1)2), Naoki Funamoto3), Sayo Nishiie3), Yasuhiro Nakamura3), Satoshi Tatumi3)
1)Medical Research Institute, Kanazawa Medical University, 2)Ginrei Lab Inc., 3)Sumitomo Riko Company Limited
Alternatives to Animal Testing and Experimentation 28 (suppl) 134-134, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-45. In vitro grafting of hepatic spheroids and organoids on a micro-uidic vascular bed
Guangyuan Zhang1), Flavio Bonanini2), Dorota Kurek2), Sara Previdi2), Delilah Hendriks3), Huili Hu3), Carmen Lopez Iglesias4), Devanjali Dutta3), Paul Vulto2), Peter J Peters4), Sebastiaan J Trietsch2), Hans Clevers3)
1)Mimetas Japan KK, 2)MIMETAS BV, 3)Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center, 4)The Maastricht Multimodal Molecular Imaging Institute, Maastricht University
Alternatives to Animal Testing and Experimentation 28 (suppl) 135-135, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-47. Research on in-ammatory bowel disease using human iPS cell-derived colonic organoids
Fuki Yokoi1), Sayaka Deguchi1), Yukio Watanabe1), Kazuo Takayama1)2)
1)Center for iPS Cell Research and Application (CiRA), Kyoto University, 2)AMED - CREST
Alternatives to Animal Testing and Experimentation 28 (suppl) 135-135, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-49. Automated 3D Cell-Based Assays in Animal Free Nanobrillar Cellulose Hydrogels for High-Throughput Screening Analyses
Yuri Ueno1), Essi M.Niemi2), Jonathan Sheard2), Piia Mikkonen2)
1)NICHIREI BIOSCIENCES INC., 2)UPM Biomedicals
Alternatives to Animal Testing and Experimentation 28 (suppl) 136-136, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-51. Characterization of Human Immortalized Cell Based Blood-Brain Barrier Spheroid Models as a Tool for Brain Vascular In-ammation Studies
Ayuka Ebisawa, Furano Kunitomo, Asuka Minasato, Hanae Morio, Tomomi Furihata
School of Pharmaceutical Sciences, Tokyo University of Pharmacy and Life Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 136-136, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-53. Development of a silkworm obesity and dyslipidemia model and its potential as a model animal in the search for materials that improve obesity and lipid metabolism
Yuki Tagawa, Shunsuke Kotani, Mikiyo Wada
Graduate School of Pharmaceutical Sciences, Kumamoto University
Alternatives to Animal Testing and Experimentation 28 (suppl) 137-137, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-55. Toward new therapeutic methods for heart disease : Xenografted of human iPS cell-derived cardiomyocyte lineage cells into zebrash
Riko Taira1), Mika Takahi1), Jo Onozuka1), Haruka Sunamura1), Akiko Kondow2), Koji Nakade3), Kenichi Nakashima3), Iori Sato3), Yohei Hayashi3), Chinmoy Parta4), Kiyoshi Ohnuma1)
1)Nagaoka University of Technology, 2)Teikyo University, 3)RIKEN, 4)Agharkar Research Institute
Alternatives to Animal Testing and Experimentation 28 (suppl) 137-137, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-57. Development of in silico models that dene the applicability domains of binary classiers : Example of ITSv2 Dened Approach for skin sensitization hazard identication
Takaho Asai, Kazuhiko Umeshita, Michiko Sakurai, Shinji Sakane
Safety & Analysis, Sunstar Inc.
Alternatives to Animal Testing and Experimentation 28 (suppl) 138-138, 2023.
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P-58. Consideration of the applicability of ChatGPT and other methods, to the "Autonomous alternatives to animal experiments"
Kohtaro Yuta
In Silico Data, Ltd
Alternatives to Animal Testing and Experimentation 28 (suppl) 138-138, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-59. Development of the prediction model for standardized ileal digestibility of protein and utilization for DIAAS evaluation
Takuya Kikuchi1), Masamichi Takeshita2), Yusuke Adachi1), Yoji Yamada1)
1)Institute of Food Sciences and Technologies, Ajinomoto Co., Inc., 2)Research Institute for Bioscience Products & Fine Chemicals, Ajinomoto Co., Inc.
Alternatives to Animal Testing and Experimentation 28 (suppl) 139-139, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-60. Development of the regression model in machine learning to predict skin sensitization intensity with avoiding the underestimation
Juri Tokunaga1), Kaori Ambe1), Takashi Yamada2), Takao Ashikaga2), Masahiro Tohkin1)
1)Department of Regulatory Science, Faculty of Pharmaceutical Science, Nagoya City University, 2)Division of Risk Assessment, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 139-139, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-61. Understanding the process of descriptor generation with chemical language model
Tadahaya Mizuno
Graduate School of Pharmaceutical Sciences, The University of Tokyo
Alternatives to Animal Testing and Experimentation 28 (suppl) 140-140, 2023.
  • 全文ダウンロード： 従量制、基本料金制の方共に121円(税込) です。
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P-62. Rapid quantication of microvascular network of 3D blood-brain barrier model using optical coherence tomography and deep learning algorithm
Huiting Zhang1), Dong Hee Kang2), Marie Piantino2), Daisuke Tominaga3), Takashi Fujimura4), Noriyuki Nakatani4), James Nicholas Taylor1), Tomomi Furihata5), Michiya Matsusaki1)2), Satoshi Fujita1)2)
1)AIST - Osaka University Advanced Photonics and Biosensing Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), 2)Graduate School of Engineering, Osaka University, 3)Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 4)SCREEN Holdings Co., Ltd., 5)School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 140-140, 2023.
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P-63. Construction of gingival epithelium and gingival vascular network for observation of bacterial invasion into gingival tissue
Yuki Sato1), Yuji Nashimoto2), Yujin Ohsugi3), Takeshi Hori2), Shotaro Yoshida1), Sayaka Katagiri3), Hirokazu Kaji2)
1)Graduate School of Science and Engineering, Chuo University, 2)Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 3)Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
Alternatives to Animal Testing and Experimentation 28 (suppl) 141-141, 2023.
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P-64. A robotised 1546 compound screen in a perfused 3D micro-uidic angiogenesis assay
Yoko Ejiri1), Camilla Soragni2)3), Jeroen Heijmans2), Arthur Stok2), Sander de Ruiter2), Johnny Suiker2), Thomas Olivier2), Marleen Bokkers2), Karla Quieroz2), Chee Ng2), Paul Vulto2), Bas Trietsch2), Jos Joore2), Henriette Lanz2)
1)Mimetas Japan KK, 2)MIMETAS BV, 3)Department of Cardiology, Maastricht University
Alternatives to Animal Testing and Experimentation 28 (suppl) 142-142, 2023.
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P-65. Fundamental study on the development of three-dimensional renal tubule model by coculture of renal tubular cells, endothelial cells and broblasts
Miyu Yamazaki, Kiichi Sato
Guraduate School of Science and Technology, Gunma University
Alternatives to Animal Testing and Experimentation 28 (suppl) 142-142, 2023.
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P-66. 3D human vascular-on-a-chip : a method to assess the endothelial-intima migration of monocytes in atherosclerosis
Ayaka Hayashida, Atsuko Nozawa, Akina Mori, Shigeaki Ito
JAPAN TOBACCO INC. Scientific Product Assessment Center
Alternatives to Animal Testing and Experimentation 28 (suppl) 143-143, 2023.
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P-67. Co-culture method for development of three dimensional microglome
Yuzuru Chiba, Kiichi Sato
Graduate School of Science and Technology, Gunma University
Alternatives to Animal Testing and Experimentation 28 (suppl) 143-143, 2023.
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P-68. Development of an expanded culture of immortalized cells derived from human monocytes (aMylc)
Toshie Kusunoki, Ami Murakami, Yua Saito, Honoka Namera, Yuka Yoshimura, Sachiko Maeno, Kazuo Miyazaki, Jun Shimizu
MiCAN Technologies Inc.
Alternatives to Animal Testing and Experimentation 28 (suppl) 144-144, 2023.
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P-69. Development of a supercooling preservation method of micro-liver models
Maaya Hikichi1), Masaru Tsunoda2), Kiichi Sato1)
1)Graduate School of Science and Technology, Gunma University, 2)Sanden Retail Systems
Alternatives to Animal Testing and Experimentation 28 (suppl) 144-144, 2023.
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P-70. In vitro Stinging Test using 3D Skin Model, hiPSC-derived Sensory Neurons, and Microelectrode Arrays (MEA)
Kosuke Onishi1), Masataku Okamura1), Satoru Miyazawa1), Megumi Sakuma1), Makoto Mizuno1), Yuto Ishibashi2), Nami Nagafuku2), Ikuro Suzuki2)
1)Research Laboratories, KOSE Corporation, 2)Department of Electronics, Graduate school of engineering, Tohoku Institute of Technology
Alternatives to Animal Testing and Experimentation 28 (suppl) 145-145, 2023.
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P-71. Inter-donor variation in a micronucleus test using the EpiAirway organotypic human airway model
Satoru Munakata, Tomohiro Takahashi, Taku Watanabe, Mayumi Ono, Tsuneo Hashizume
Japan Tobacco Inc.
Alternatives to Animal Testing and Experimentation 28 (suppl) 145-145, 2023.
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P-72. Improvement of the versatility of the CNN model for focus determination in the Bhas42 cell transformation assay
Shuhei Yamamoto1), Kiyomi Ohmori1)2), Wakana Uchida3), Yasuko Onuma3), Natsumi Yamagishi3), Kenji Miyamoto4), Kento Uchida1), Shinichi Shirakawa1), Junji Fukuda1)
1)Graduate School of Engineering Science, Yokohama National University, 2)Kanagawa Prefectural, Institute of Public Health, 3)NIKON CORPORATION, 4)NIKON SOLUTIONS CO., LTD
Alternatives to Animal Testing and Experimentation 28 (suppl) 146-146, 2023.
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P-73. Development of alternative in vitro assay for detecting mitochondrial permeability transition pore opening using Platelet activation
Atsuya Fujita1), Akinori Takemura2), Kousei Ito2)
1)Faculty of Pharmaceutical Sciences, Chiba University, 2)Graduate School of Pharmaceutical Sciences, Chiba University
Alternatives to Animal Testing and Experimentation 28 (suppl) 146-146, 2023.
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P-74. Development of a liver chip that can evaluate biliary excretion of pharmaceuticals using normal human hepatocytes
Kensei Suzuki1), Shoka Takebayashi1), Takumi Kubo2), Makoto Yamanaka2), Kenichi Hirose2), Kenji Hatakeyama2), Yuji Komizu1), Taku Matsushita1), Seiichi Ishida1)3)
1)Division of Applied Life Science, Graduate School of Engineering, Sojo University, 2)USHIO Inc, 3)Division of Pharmacology, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 28 (suppl) 147-147, 2023.
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P-75. Drosophila melanogaster as an Alternative Animal Model for Assessing Acute Inhalation Toxicity
Yoon Cho, Chul Min Park, Yong Ju Heo, Hae Bin Park, Min Seok Kim
Korea Institute of Toxicology
Alternatives to Animal Testing and Experimentation 28 (suppl) 147-147, 2023.
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P-76. Evaluation of neurotoxicity for pesticides in human iPS cell-derived neurons using microelectrode array
Yuto Ishibashi, Nami Nagafuku, Ikuro Suzuki
Faculty of Engineering, Tohoku Institute of Technology
Alternatives to Animal Testing and Experimentation 28 (suppl) 148-148, 2023.
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P-77. Next Generation Safety Assessment of Cosmetics by Read-across Using Existing Information - A Case Study of Systemic Toxicity Assessment with Ethoxyethanol -
Tomomi Atobe, Tomoka Hisaki, Hirokazu Kozuki
Brand Value R & D Institute, Shiseido Co., Ltd
Alternatives to Animal Testing and Experimentation 28 (suppl) 148-148, 2023.
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P-78. Development of toxicity evaluation model for PM 2.5 using human iPS cell-derived cardiomyocytes
Yuki Tohyama1), Toshiki Saotome1), Naoki Shimada1), Kohei Sawada1)2)
1)R & D Center, The Japan Wool Textile Co., Ltd., 2)Pharmacological Evaluation Institute of Japan (PEIJ)
Alternatives to Animal Testing and Experimentation 28 (suppl) 149-149, 2023.
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P-79. Automated measurement system using C. elegans to evaluate lifespan and healthspan
Tsuyoshi Shuto, Yutaro Fukushima, Asuka Kagami, Yoshio Nakano, Masataka Moriuchi, Hirotaka Sonoda, Kotomi Shimokawa, Mary Ann Suico, Hirofumi Kai
Graduate School of Pharmaceutical Sciences, Kumamoto University
Alternatives to Animal Testing and Experimentation 28 (suppl) 149-149, 2023.
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P-80. Research on the development of alternative animal testing methods for neurotoxic chemicals using Bombyx mori
Motoki Hida1), Hidenobu Okumura2), Shinichi Ogata1)
1)Department of Environment and Information Sciences, Yokohama National University, 2)Institute of Beauty and health science
Alternatives to Animal Testing and Experimentation 28 (suppl) 150-150, 2023.
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P-81. In-situ electrochemical cell analysis using a porous membrane electrode
Yoshinobu Utagawa1), Kosuke Ino1), Hiroya Abe1)2), Hitoshi Shiku1)
1)Graduate School of Engineering, Tohoku University, 2)Frontier Research Institute for Interdisciplinary Sciences, Tohoku University
Alternatives to Animal Testing and Experimentation 28 (suppl) 150-150, 2023.
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P-82. Development of a method for detecting endocrine disrupting effects of chemicals on sex steroid hormones using quail embryos
Kazuhiro Sano, Kyoko Watanabe, Win Shwe Tin Tin, Takehiro Suzuki, Takaharu Kawashima
Health and Environmental Risk Division, National Institute for Environmental Studies
Alternatives to Animal Testing and Experimentation 28 (suppl) 151-151, 2023.
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P-83. Simple and efcient in vitro culture method of quail embryos during organogenesis using multi-well plate
Takaharu Kawashima, Kyoko Watanabe, Kazuhiro Sano, Win Shwe Tin Tin, Takehiro Suzuki
Health and Environmental Risk Division, National Institute for Environmental Studies
Alternatives to Animal Testing and Experimentation 28 (suppl) 151-151, 2023.
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P-84. Case study of resveratrol as a cosmetic ingredient for systemic toxicity using the new approach methods of next generation risk assessment
Takumi Nukaga, Shuichi Sekine, Tomoka Hisaki, Kosuke Imai, Morihiko Hirota, Akiko Tamura
Brand Value R & D Institute, Shiseido Co., Ltd.
Alternatives to Animal Testing and Experimentation 28 (suppl) 152-152, 2023.
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P-85. Evaluation of drug toxicity to spheroid using image analysis
Kazuki Hisamitsu1), Yoko Igarashi2), Hiroshi Suganuma2), Yoshihiko Watanabe1), Nobuhiko Kojima1)
1)Yokohama City University, 2)Sumitomo Electric Industries, Ltd
Alternatives to Animal Testing and Experimentation 28 (suppl) 152-152, 2023.
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P-86. Development of serotonin release assay with cultured enterochromafn cells for the risk assessment for drug-induced emesis
Yoshiki Hashimoto1), Kazuya Maeda1)2), Osamu Shimomura3), Yoshihiro Miyazaki3), Shinji Hashimoto3), Tatsuya Oda3), Hiroyuki Kusuhara1)
1)Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2)School of Pharmacy, Kitasato University, 3)Faculty of Medicine, University of Tsukuba
Alternatives to Animal Testing and Experimentation 28 (suppl) 153-153, 2023.
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