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Alternatives to Animal Testing and Experimentation 6巻 4号

発行元
日本動物実験代替法学会
ISSN
1344-0411
ISSN(オンライン)
2185-4726

書籍情報から探す
開始頁
Current Status of Development of Alternative Test Methods in Europe
Tasuku Takamatsu
Life Science Research Center, R&D Headquarters, Shiseido Co.,Ltd.
Alternatives to Animal Testing and Experimentation 6 (4) 129-135, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
F-3. Significance of Experimental Animals in Safety Assessment of Chemicals
Hiroshi Ono
Hatano Research Institute, Food and Drug Safety Center
Alternatives to Animal Testing and Experimentation 6 (4) 140-140, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
F-4. Animal Experimentation is a Prerequisite for Biomedical Research
Tsutomu Miki Kurosawa
Osaka Universi Medical School
Alternatives to Animal Testing and Experimentation 6 (4) 140-141, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
F-5. Safety Evaluation and Animal Alternative
Akihiro Kurishita
Research and Development Department, Japan Technical External Relations, Protecr & Gamble Far East Inc.
Alternatives to Animal Testing and Experimentation 6 (4) 141-141, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
F-6. Concept of Animal Welfare and Research on the Alternative for Animal Experimentation
Atsushige Sato
Space Utilization Research Programme, National Space Development Agency of Japan
Alternatives to Animal Testing and Experimentation 6 (4) 141-142, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
W-1 Is the Human Risk Assessment Possible with Animal Skin Toxicity Testing?
Hajime Kojima
Research Laboratories, Nippon Menard Cosmetic Co.,Ltd.
Alternatives to Animal Testing and Experimentation 6 (4) 142-142, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
W-2. A New Serum-Free Medium, EpiLife(TM), Greatly Extends the Lifespan of Cultured Human Keratinocytes Making Large Banks of Highly-Characterized Normal Epithelial Cells Possible
S.Li1, L.M.Donahue1, A.K.Shipley1, K.A.Droms1, Y.Lin1, G.D.Shipley1, M.Genno2, S.Niwata2, R.Yamamoto2
1Cascade Biologics, Inc., 2Kurabo Industries, Ltd.
Alternatives to Animal Testing and Experimentation 6 (4) 142-143, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
W-3. Alternative Skin Irritation Test Methods Using Living Skin Equivalent
Takuya Ishibashi1, Hidekazu Takahashi1, Mikio Nakagawa2, Keiichi Kawai2
1Toyobo Co.,Ltd., Tsuruga Institute of Biotechnology, 2Kawai Medical Laboratory for Cutaneous Health
Alternatives to Animal Testing and Experimentation 6 (4) 143-143, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
W-4. The Present Researches of Cultured Skin Model:Impression of Third World Congress on Alternatives and Animal Use in the Life Sciences
Katsuyasu Morota
Research and Development Division, GUNZE Ltd.
Alternatives to Animal Testing and Experimentation 6 (4) 143-143, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
W-5. Present Situation of Skin Toxicity Evaluation in Europe
Tasuku Takamatsu
Shiseido Life Science Research Center
Alternatives to Animal Testing and Experimentation 6 (4) 143-143, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
W-6. Present Situation of Skin Toxicity Evaluation in US and in Japan
Yasuo Ohno
Divisoin of Pharmacol., BSRC, Nat. Inst. Health Sci
Alternatives to Animal Testing and Experimentation 6 (4) 144-144, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
PL. Conjugate-Dependent Toxicity:Alternatrves to Animal Studies
M.W.Anders
Department of Pharmacology and Physiology, University of Rochester Medical Center
Alternatives to Animal Testing and Experimentation 6 (4) 144-146, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
AW-1. Validation Study on Five Cytotoxicity Assays by JSAAE II. Statistical Analysis
T.Omori1, K.Saijo2, M.Kato2, M.Hayashi3, H.Itagaki4, S.Miyazaki5, T.Ohno2, H.Sugawara5, N.Teramoto2, N.Tanaka6, S.Wakuri6, I.Yoshimura1
1Scrence University of Tokyo, 2RIKEN Cell Bank, 3National Institute of Health Sciences, 4Shiseido Safety Analytical Research Center, 5National Institute of Genetics, 6Food and Drug Safety Center
Alternatives to Animal Testing and Experimentation 6 (4) 146-146, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
AW-2. Evaluation of Skin Irritation in a Reconstituted Human Dermal Model (3-D Model) Using Water Insoluble Fatty Acid, Fatty Alchols and Hydrocarbons
Hajime Kojima, Atsushi Sato, Asao Hanamura, Tomonori Katada, Hiroaki Konishi
Research laboratories, Nippon Menard Cosmetic Co.,Ltd.
Alternatives to Animal Testing and Experimentation 6 (4) 146-147, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
AW-3. Experience of 1st Validation Study on Five Different Cytotoxicity Assays
Tadao Ohno
RIKEN (The Institute of Physical and Chemical Research)
Alternatives to Animal Testing and Experimentation 6 (4) 147-147, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
S-1. Framework of the Use of Human Materials in Pharmacogenetics:the Aim of This Symposium.
Tohru Masui
National Institute for Health Sciences, Division of Mutation and Genetics, Cell Bank
Alternatives to Animal Testing and Experimentation 6 (4) 147-148, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
S-2. Genetically Engineered Mammarian Cells, Bacteria And Teansgenic Animals Carrying Human Drug Metabolizing Enzymes:Perspcitives
Tetsuya Kamataki
Division of Drug Metabolism, Graduate School of Pharmaceutical Sciences, Hokkaido University
Alternatives to Animal Testing and Experimentation 6 (4) 148-148, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
S-3. Functional Expression of Drug Metabolizing Enzymes in Novel Established Human Hepatoma Cell Lines and CDNA Epressed in Mammlian Cell Lines
Masakiyo Hosokawa1, Hiroko Shinohara1, Yoko Tanaka1, Eiko Tsukada1, Mieko Mori1, Maki Fukumoto1, Yuko Ogasawara1, Seishi Nagamori2, Kan Chiba1
1Faculty of Pharmaceutical Sciences, Chiba University, 2Department of Internal Medicine, The Jikei University School of Medicine
Alternatives to Animal Testing and Experimentation 6 (4) 148-148, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
S-4. High Throughput Monitoring of Hepatic Drug Metabolizing Enzymes Using Human Blood Tissues
Shogo Ozawa
Division of Pharmacology, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 6 (4) 149-150, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
  • 全文ダウンロード: 従量制、基本料金制の方共に121円(税込) です。
S-5. Ethical Considerations on the Use of Human Tissues and Cells
Toshiharu Matsumura
Meiji Cell Technology Center, Meiji Milk Products, Co.Ltd.
Alternatives to Animal Testing and Experimentation 6 (4) 150-151, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
S-6. Ethics of Human DNA Sampling
Hiraku Takebe
Atomic Energy Research Institute, Kinki University
Alternatives to Animal Testing and Experimentation 6 (4) 151-151, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
S-7. Biosafety in Laboratories Working with Human Materials
Reiko Hirai
The Tokyo Metropolitan Institute of Medical Science
Alternatives to Animal Testing and Experimentation 6 (4) 151-151, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
S-8. Human Materials Resource in Japan:Present and Future Perspectives
Tetsuo Satoh1, Satoshi Suzuki1, Norimitsu Kurata2, Yuki Noshimura2, Mariko Iwase2, Hua Li2, Youji Ito3, Mitsuo Kusano3, Yasuo Ohno4, Eiji Uchida2, Hajime Yasuhara2
1Biomedical Research Institute, School of Medicine, Showa University, 2Department of Pharmacology, School of Medicine, Showa University, 3Department of Surgery, School of Medicine, Showa University, 4National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 6 (4) 152-152, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
S-9. Public Research Resources:Human cell
Hiroshi Mizusawa
JCRB cell bank, National Institute of Health Sciences
Alternatives to Animal Testing and Experimentation 6 (4) 152-152, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-1. Developmental Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin(TCDD) and Some of Its Relaed Compounds in Xenopus Laevis
Shin Mima1, Michiko Sakamoto2, Takashi Tanrmura3
1Osaka Women's Junior College, 2Department of Anatomy, School of Medicine, 3Life Science Research Institute, Kinki University
Alternatives to Animal Testing and Experimentation 6 (4) 152-153, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-2. Pharmacological and Toxicological Studies Using Chick Embryos (14) Diabetes Model in Chick Embryos Treated with Streptozotocin
Takashi Sugiyama1, Miyuki Itoh1, Mariko Fukumoto2, Hideyo Shimada1,3, Kanji Tsuchimoto1,3.
1Division of Pathophysiology, Center for Clinical Pharmacy and Clinical Sciences, School of Pharmaceutical Sciences, Kitasato University, 2Division of Toxicology, Center for Clinical Pharmacy and Clinical Sciences, School of Pharmaceutical Sciences, Kitasato University, 3Kitasato Institute Hospital
Alternatives to Animal Testing and Experimentation 6 (4) 153-153, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-3. In Vitro Embryotoxicity Testing of Metals for Dental Use by Differentiation of Embryonic Stem cells into Contracting Cardiac Myocytes
Koichi Iman1, Horst Spielmann2, Gabriele Scholz2, Ingeborg Pohl2, Masaaki Nakamura1
1Dept. of Biomaterials, Osaka Dental Univ., 2ZEBET, BgVV, Germany
Alternatives to Animal Testing and Experimentation 6 (4) 153-154, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-4. Evaluation of Embryotoxicity of Estradiol Benzoate and Diethylstilbestrol Using Whole Embryo Culture
Makiko Kuwagata1, Chiaki Watanabe1, Hiromasa Takashima1, Hiroaki Aoyama2, Toshiaki Watanabe3, Hiroshi Ono1
1Hatano Research Institute Food and Drug Safety Center, 2Institute of Environmental Toxicology, 3Yamagata University School of Medicine
Alternatives to Animal Testing and Experimentation 6 (4) 154-154, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-5. A New Differentiation Marker in Cultured Whole Embryos Neuronal Connections with Sensory Organs, in Special Reference to Vibrissa Rudiments
Makoto Yamakado1, Masaharu Akita2, Atsushi Yokoyama2, Yukiaki Kuroda3
1Jichi Medical School, 2Kamakura Women's College, 3National Institute of Genetics
Alternatives to Animal Testing and Experimentation 6 (4) 154-155, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-6. The Histological Study of Whole Rat Embryos Cultured in Rat I.C. Serum Produced by Imamichi Institution of Animal Reproduction
Masaharu Akita1, Atsushi Yokoyama1, Shigekazu Shimizu2, Hiroo Shikuma2, Yoshihiro Nozaki2, Yukiaki Kuroda3
1Kamakura Women's College, 2Fuji Biomedix Co.Lim., 3National Institute of Genetics
Alternatives to Animal Testing and Experimentation 6 (4) 155-155, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-7. Effects of Trichlorobenzene as Endocrine Disrupting Chemical on Cultured Rat Embryos
Atsushi Yokoyama1, Masaharu Akita1, Yukiaki Kuroda2
1Kamakura Women's College, 2National Institute of Genetics
Alternatives to Animal Testing and Experimentation 6 (4) 155-156, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-8. Effects of Monochlorobenzene as an Endocrine Disrupting Chemical on Cultured Rat Embryos
Atsushi Yokoyama1, Masaharu Akita1, Yukiaki Kuroda2
1Kamakura Women's College, 2National lnstitute of Genetics
Alternatives to Animal Testing and Experimentation 6 (4) 156-156, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-9. Effects of Bisphenol A on Cultured Rat Embryos
Masaharu Akita1, Atsushi Yokoyama1, Yukiaki Kuroda2
1Kamakura Women's College, 2National Institute of Genetics
Alternatives to Animal Testing and Experimentation 6 (4) 156-156, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-10. Establishment of Downs Syndrome Cells to Study Cytotoxicity of Dental Materials
Yoshitomo Ogawa1, Mikio Kato1, Daito Michiharu1, Koichi Imai2
1Department of Pediatric Dentistry, Osaka Dental University, 2Department of Biomaterials, Osaha dental University
Alternatives to Animal Testing and Experimentation 6 (4) 157-157, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-11. Inhibitory Effect of Enviromental Endocrine Disruptors on Thymosin α1 Production in Thymus Epithelial Cell Culture
Kou Sakabe1, Takahiko Yoshida2, Hiroyuki Aikawa2, Shun-ichiro Izumi3, Yoshiyuki Osamura4, Fujio Kayama5
1Department of Morphology, 2Department of Environmental Health, 3Department of Obstetrics and Gynecology, 4Department of Pathology, Tokai University School of Medicine, 5Department of Environmental Health, Jichi Medical School
Alternatives to Animal Testing and Experimentation 6 (4) 157-158, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-12. Carcinogen Detection Potential of the BALB/3T3 Cell Taansformation Assay by Using a Medium Supplemented with Low Concentration of Serum and Some Growth Factors (Improved Assay Method)
Yoshitsugu Kajiwara, Syozo Ajimi
Chemicals Inspection & Testing Institute
Alternatives to Animal Testing and Experimentation 6 (4) 158-159, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-13. Kinetic Analysis of Cell Killing Effect Induced by Busulfan in Chinese Hamster Cells
Mariko Fukumoto1, Takashi Sugiyama2, Eriko Mitsuoka1, Akira Ogamo1, Kanji Tsuchimoto1
1Division of Toxicology, Center for Clinical Pharmacy and Clinical Sciences, School of Pharmaceutical Sciences, Kitasato University, 2Division of Pathophysiology, Center for Clinical Pharmacy and Clinical Sciences, School of Pharmaceutical Sciences, Kitasato University
Alternatives to Animal Testing and Experimentation 6 (4) 159-159, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-14. Preparation and Evaluation of Artificial Membrane for Prediciting in Vitro Human Skin Absorption of Drugs
Aki Matsuda1, Sachihiko Numajiri1, Daisuke Kobayashi1, Hideshi Natsume1, Masahiko Ogihara1, Yasunori Morimoto1, Ken Ichikawa2, Kurao Sudo2, Hiromi Kitano2
1Faculty of Pharmaceutrcal Scrences Josai University, 2Faculty of Engineering, Toyama University
Alternatives to Animal Testing and Experimentation 6 (4) 160-160, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-15. Validation of the Neutral Red Uptake Phototoxicity Method Using Three Cell Lines
Mariko Sugiyama, Hiroshi Itagaki, Yoshio Katsumura, Shinobu Kato
Shiseido Life Science Research Center
Alternatives to Animal Testing and Experimentation 6 (4) 160-160, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-16. Evaluation of Cell Recovery Test Using a 3-Dimensional Human Cell Epidermis Model and Closed Patch Test for Skin Irritation Test
Matsumi Terasawa, Noriko Nakagawa
IVY COSMETICS Co.,LTD.
Alternatives to Animal Testing and Experimentation 6 (4) 160-161, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-17. Potential of LSE-High (Living Skin Equivlent) as a Model Membrane to Evaluate Skin Permeation and Skin Irritation of Drugs
Tetsuya Watanabe1, Tetsuya Hasegawa1, Hidekazu Takahashi2, Takuya Ishibashi2, Masakazu Kiuchi3, Kozo Takayama1, Kenji Sugibayashi3
1Josai University, 2Toyobo Bro Laboratory, 3Hoshi University
Alternatives to Animal Testing and Experimentation 6 (4) 161-161, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-18. Evaluation of Cosmetic Ingredients with Cultured Human Skin Model
Tamie Suzuki, Masaki Uda, Itaru Miyamoto, Takao Ishida
Central Research Laboratory, FANCL Corporation
Alternatives to Animal Testing and Experimentation 6 (4) 161-161, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-19. In Vitro Systems for the Quantitative Predicton of Drug Interactions via the Hepatobiliary Transporers
Yukio Kato1,2, Kanji Komatsu1, Kaoru Ueda1, Hiroshi Suzuki1,2, Yuichi Sugiyama1,2
1Graduate School of Pharmaceutlcal Sciences University of Tokyo, 2CREST, Japan
Alternatives to Animal Testing and Experimentation 6 (4) 162-162, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-20. Cryopreserved Human Hepatocytes as a Tool for the prediction of in vivo Drug Transport and Transporter-Mediated Drug-Drug Interactions
Yoshihisa Shitara1, Chuang Lu2, Albert P.Li2, Yukio Kato3, Hiroshi Suzuki3, Kiyomi Ito1, Tomoo Itoh1, Yuichi Sugiyama3
1Kitasato University, 2In Vitro Technologies, 3The University of Tokyo
Alternatives to Animal Testing and Experimentation 6 (4) 162-162, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-21. Development of a simple Multi-Compartment Perfusion-Culture System for Toxicity Testing Including Absorption and Biotransformation Processes
Motoyuki Suzuki, Terumasa Ohiso, Yasuyuki Sakai, Akiyoshi Sakoda
Institute of Industrial Science, University of Tokyo
Alternatives to Animal Testing and Experimentation 6 (4) 162-163, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。
P-22. The Establishment and Characterizaton of Kidney-Derived Cell Lines Expressing Human Organic Anion Transporter 1 and 3 (hOAT1 and hOAT3)
Shin-ichi Narikawa, Takashi Sekine, Seok Ho Cha, Makoto Hosoyamada, Michio Takeda, Hitoshi Endou
Department of Pharmacology and Toxicology, Kyorin University School of Medicine
Alternatives to Animal Testing and Experimentation 6 (4) 163-163, 2000.
  • アブストラクト: 従量制は110円(税込)、基本料金制は基本料金に含まれます。