アブストラクト
Title | 大腸癌肝転移の周術期化学療法 |
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Subtitle | 特集 周術期化学療法の現状と展望 |
Authors | 岡崎聡, 石川敏昭, 植竹宏之* |
Authors (kana) | |
Organization | *東京医科歯科大学大学院・総合外科学 |
Journal | 癌と化学療法 |
Volume | 47 |
Number | 4 |
Page | 574-577 |
Year/Month | 2020 / 4 |
Article | 報告 |
Publisher | 癌と化学療法社 |
Abstract | 「要旨」 大腸癌肝転移の周術期化学療法には肝切除後の再発抑制や予後延長を目的として行う補助化学療法と, 切除不能な肝転移を手術に持ち込む「conversion」をめざした術前補助化学療法がある. 補助化学療法について全生存期間の延長に結び付くレジメンや施行時期は明らかになっていないが, 術後の5-FU/LV療法(静注または内服)による再発抑制効果が示されている. conversionをめざして行う術前補助化学療法では, FOLFOXやFOLFIRIとの分子標的薬併用療法またはFOL FOXIRI+bevacizumab療法で高い奏効率と肝切除率が期待できる. |
Practice | 臨床医学:一般 |
Keywords | Colorectal liver metastasis (CRLM), Perioperative chemotherapy, Conversion therapy |
- 全文ダウンロード: 従量制、基本料金制の方共に913円(税込) です。
参考文献
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