アブストラクト
Title | 敗血症の治療 |
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Subtitle | 特集 敗血症 - 再考,そして未来へ (II) |
Authors | 垣内大樹*, 佐々木淳一* |
Authors (kana) | |
Organization | *慶應義塾大学医学部救急医学 |
Journal | 医学と薬学 |
Volume | 78 |
Number | 3 |
Page | 205-212 |
Year/Month | 2021 / 3 |
Article | 報告 |
Publisher | 自然科学社 |
Abstract | 「はじめに」敗血症の定義や治療は1990年代よりさまざまな変遷を遂げ, 現在の敗血症の定義は2016年に発表された「感染により重篤な臓器障害が引き起こされる状態」(Sepsis-3)となり, その定義の下にSurviving Sepsis Campaign Guideline 2016(SSCG2016)や日本版敗血症診療ガイドライン2016(J-SSCG2016)が作成された. 今般, 2020年9月には2016年以降の4年間に発表されたエビデンス等に基づき, 本邦よりJ-SSCG 2020が世界に先駆けて公開された. 敗血症関連死亡は全世界で年間1,100万人(全世界の死亡者の19.7%に相当)とされ, 本邦でも敗血症推定患者数は人口10万対4,600人と想定されており, common diseaseである. さらに先進国での敗血症の死亡率は18.4〜19.0%, 敗血症性ショックの死亡率は38%と報告されており, いまだ死亡率が高い. 敗血症の診療では早期診断・早期治療が重要であり, Surviving Sepsis CampaignからはHour-1 bundleが提唱されており, J-SSCG2020でも時間軸を意識した診療フローが新しく記載されるようになった. |
Practice | 医学総合 |
Keywords | Sepsis, J-SSCG2020, Antimicrobials, Vasopressor, Steroid |
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残りの23件を表示する
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