アブストラクト
| Title | 小児発症IBDの疫学とその特徴を知る |
|---|---|
| Subtitle | 特集 日本のIBDの疫学を理解する! |
| Authors | 南部隆亮* |
| Authors (kana) | なんぶりゅうすけ |
| Organization | *埼玉県立小児医療センター 消化器・肝臓科 |
| Journal | IBD Research |
| Volume | 18 |
| Number | 2 |
| Page | 92-97 |
| Year/Month | 2024 / 6 |
| Article | 報告 |
| Publisher | 先端医学社 |
| Abstract | 小児期発症の炎症性腸疾患(IBD)患者数は世界中で増加の一途を辿っている. とくに近年は, 診断時年齢の低下があいついで報告されており, 今後6歳未満発症のIBD(VEO-IBD)もますます増加していくと予想される. 小児IBDの特徴は, (1)重症・難治例が多い, (2)成長障害をきたす, (3)非典型的が多い, そして(4)IBDのなかに単一遺伝子疾患に合併するIBD(monogenic IBD)が紛れていることである. monogenic IBDの新規原因遺伝子の報告があいつぎ, 現在ではその数は80を超える. monogenic IBDは典型的なIBDとは治療法が異なることがあり, 患者の病態に合わせたprecision medicineをおこなうためにmonogenic IBDを疑い遺伝子検査を経て診断することが重要である. |
| Practice | 臨床医学：内科系 |
| Keywords | 小児IBD, VEO-IBD, monogenic IBD, IBD-U, 先天性免疫異常症 |
- 全文ダウンロード： 従量制、基本料金制の方共に935円(税込) です。
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