アブストラクト
Title | レビー小体型認知症の前駆症状 |
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Subtitle | 特集 レビー小体型認知症診療のstate-of-the-art |
Authors | 岩田(遠藤)邦幸*1, 藤城弘樹*2 |
Authors (kana) | |
Organization | *1松蔭病院, 名古屋大学大学院医学系研究科精神医学, *2名古屋大学大学院医学系研究科精神医学, かわさき記念病院 |
Journal | 老年精神医学雑誌 |
Volume | 33 |
Number | 5 |
Page | 419-428 |
Year/Month | 2022 / 5 |
Article | 報告 |
Publisher | ワールドプランニング |
Abstract | 「抄録」 2020年にレビー小体型認知症(DLB)の前駆状態(prodromal DLB)の3つの臨床亜型が提示された. レム睡眠行動障害と嗅覚低下, 便秘・起立性低血圧などの自律神経障害はDLBとパーキンソン病(PD)に共通する重要な前駆症状である. 本稿では, その異同を含めて, prodromal DLB診断における注意点や治療介入の可能性について考察した. |
Practice | 臨床医学:内科系 |
Keywords | レビー小体病, prodromal DLB, MCI-LB, delirium-onset DLB, psychiatric-onset DLB |
- 全文ダウンロード: 従量制、基本料金制の方共に968円(税込) です。
参考文献
- 1) Abdelnour C, van Steenoven I, Londos E, Blanc F, et al. ; European DLB Consortium : Alzheimer's disease cerebrospinal fluid biomarkers predict cognitive decline in lewy body dementia. Mov Dis-ord, 31(8) : 1203-1208(2016).
- 2) Adler CH, Dugger BN, Hentz JG, Hinni ML, et al.: Peripheral synucleinopathy in early Parkinson's disease ; Submandibular gland needle biopsy find-ings. Mov Disord, 32(5) : 722-723(2017).
- 3) Albert MS, DeKosky ST, Dickson D, Dubois B, et al.: The diagnosis of mild cognitive impairment due to Alzheimer's disease ; Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement, 7(3) : 270-279(2011).
- 4) Antelmi E, Donadio V, Incensi A, Plazzi G, et al.: Skin nerve phosphorylated alpha-synuclein depos-its in idiopathic REM sleep behavior disorder. Neurology, 88(22) : 2128-2131(2017).
- 5) Baba T, Kikuchi A, Hirayama K, Nishio Y, et al.: Se-vere olfactory dysfunction is a prodromal symp-tom of dementia associated with Parkinson's dis-ease ; A 3 year longitudinal study. Brain, 135(Pt 1) : 161-169(2012).
残りの63件を表示する
- 6) Backstrom DC, Eriksson Domellof M, Linder J, Olsson B, et al.: Cerebrospinal Fluid Patterns and the Risk of Future Dementia in Early, Incident Parkinson Disease. JAMA Neurol, 72(10) : 1175-1182(2015).
- 7) Berg D, Postuma RB, Adler CH, Bloem BR, et al.: MDS research criteria for prodromal Parkinson's disease. Mov Disord, 30(12) : 1600-1611(2015).
- 8) Braak H, Del Tredici K, Rub U, de Vos RA, et al.: Staging of brain pathology related to sporadic Par-kinson's disease. Neurobiol Aging, 24(2) : 197-211(2003).
- 9) Chiba Y, Fujishiro H, Iseki E, Ota K, et al.: Retro-spective survey of prodromal symptoms in demen-tia with Lewy bodies ; Comparison with Alzheimer's disease. Dement Geriatr Cogn Dis-ord, 33(4) : 273-281(2012).
- 10) Doppler K, Jentschke HM, Schulmeyer L, Vadasz D, et al.: Dermal phospho-alpha-synuclein depos-its confirm REM sleep behaviour disorder as pro-dromal Parkinson's disease. Acta Neuropathol, 133(4) : 535-545(2017).
- 11) Fearnley JM, Lees AJ : Ageing and Parkinson's dis-ease ; Substantia nigra regional selectivity. Brain, 114(Pt 5) : 2283-2301(1991).
- 12) Ferini-Strambi L, Carli G, Casoni F, Galbiati A : Restless Legs Syndrome and Parkinson Disease ; A Causal Relationship Between the Two Disor-ders? Front Neurol, 9 : 551(2018).
- 13) Ferman TJ, Smith GE, Boeve BF, Graff-Radford NR, et al.: Neuropsychological differentiation of dementia with Lewy bodies from normal aging and Alzheimer's disease. Clin Neuropsychol, 20(4) : 623-636(2006).
- 14) Fujishiro H, Iseki E, Kasanuki K, Chiba Y, et al.: A follow up study of non-demented patients with primary visual cortical hypometabolism ; Prodro-mal dementia with Lewy bodies. J Neurol Sci, 334(1-2) : 48-54(2013).
- 15) Fujishiro H, Iseki E, Nakamura S, Kasanuki K, et al.: Dementia with Lewy bodies ; Early diagnos-tic challenges. PSYCHOGERIATRICS, 13(2) : 128-138(2013),
- 16) Fujishiro H : Effects of gabapentin enacarbil on restless legs syndrome and leg pain in dementia with Lewy bodies. PSYCHOGERIATRICS, 14(2) : 132-134(2014).
- 17) Fujishiro H, Nakamura S, Sato K, Iseki E : Prodro-mal dementia with Lewy bodies. Geriatr Gerontol Int, 15(7) : 817-826(2015).
- 18) Fujishiro H, Kawakami I, Oshima K, Niizato K, et al.: Delirium prior to dementia as a clinical phe-notype of Lewy body disease ; An autopsied case report. Int Psychogeriatr, 29(4) : 687-689(2017).
- 19) Fujishiro H, Okuda M, Iwamoto K, Miyata S, et al.: Early diagnosis of Lewy body disease in patients with late-onset psychiatric disorders using clinical history of rapid eye movement sleep behavior dis-order and[123I]-metaiodobenzylguanidine cardiac scintigraphy. Psychiatry Clin Neurosci, 72(6) : 423-434(2018).
- 20) Fujishiro H, Ota K, Yamagata M, Ito T, et al.: Early diagnosis of prodromal dementia with Lewy bodies using clinical history of probable REM sleep be-haviour disorder and cardiac 123I-MIBG scintigra-phy in memory clinics. PSYCHOGERIATRICS, 21(3) : 288-295(2021).
- 21) Geurtsen GJ, Hoogland J, Goldman JG, Schmand BA, et al. ; MDS Study Group on the Validation of PD-MCI Criteria : Parkinson's disease mild cogni-tive impairment ; Application and validation of the criteria. J Parkinsons Dis, 4(2) : 131-137(2014).
- 22) Giampa M, Amundarain MJ, Herrera MG, Tonali N, et al.: Implementing Complementary Approaches to Shape the Mechamsm of α-Synuclein Oligomer-ization as a Model of Amyloid Aggregation. Mole-cules, 27(1) : 88(2021).
- 23) Gore RL, Vardy ER, O'Brien JT : Delirium and de-mentia with Lewy bodies ; Distinct diagnoses or part of the same spectrum? J Neurol Neurosurg Psychiatry, 86(1) : 50-59(2015).
- 24) 長谷川康博 : 血圧調節障害の治療 ; 起立性低血圧・臥位高血圧/食事性低血圧. 神経治療学, 13(3) : 229-236(1996).
- 25) 長谷川康博 : ブドウ糖負荷試験. (日本自律神経学会編)自律神経機能検査 第4版, 144-148, 文光堂, 東京(2007).
- 26) Hogl B, Stefani A, Videnovic A : Idiopathic REM sleep behaviour disorder and neurodegeneration ; An update. Nat Rev Neurol, 14(1) : 40-55(2018).
- 27) Inagawa Y, Kanetaka H, Tsugawa A, Sakurai S, et al.: Efficacy of Olfactory and Pareidolia Tests Compared With That of Indicative Biomarkers in Diagnosis of Dementia With Lewy Bodies. Front Neurol, 11 : 540291(2020).
- 28) 井関栄三 : レビー小体型認知症 ; 臨床と病態. 中外医学社, 東京(2014).
- 29) Jack CR Jr, Bennett DA, Blennow K, Carrillo MC, et al. ; Contributors : NIA-AA Research Frame-work ; Toward a biological definition of Alzheimer's disease. Alzheimers Dement, 14(4) : 535-562(2018).
- 30) Kantarci K, Yang C, Schneider JA, Senjem ML, et al.: Antemortem amyloid imaging and β-amyloid pathology in a case with dementia with Lewy bod-ies Neurobiol Aging, 33(5) : 878-885(2012).
- 31) Klingelhoefer L, Bhattacharya K, Reichmann H : Restless legs syndrome. Clin Med(Lond), 16(4) : 379-382(2016).
- 32) Kobayashi K, Nakano H, Akiyama N, Maeda T, et al.: Pure psychiatric presentation on the Lewy body disease is depression ; An analysis of 60 cas-es verified with myocardial meta-iodobenzylguani-dine study. Int J Geriatr Psychiatry, 30(6) : 663-668(2015).
- 33) Kosaka K, Oyanagi S, Matsushita M, Hori A : Pre-senile dementia with Alzheimer-, Pick- and Lewy-body changes. Acta Neuropathol, 36(3) : 221-233(1976).
- 34) Kosaka K : Diffuse Lewy body disease in Japan. J Neurol, 237(3) : 197-204(1990).
- 35) Litvan I, Goldman JG, Troster AI, Schmand BA, et al.: Diagnostic criteria for mild cognitive impair-ment. in Parkinson's disease ; Movement Disorder Society Task Force guidelines. Mov Disord, 27(3) : 349-356(2012).
- 36) McKeith IG, Perry RH, Fairbairn AF, Jabeen S, et al.: Operational criteria for senile dementia of Lewy body type(SDLT). Psychol Med, 22(4) : 911-922(1992).
- 37) McKeith IG, Dickson DW, Lowe J, Emre M, et al. ; Consortium on DLB : Diagnosis and management of dementia with Lewy bodies ; Third report of the DLB Consortium. Neurology, 65(12) : 1863-1872(2005).
- 38) McKeith IG, Boeve BF, Dickson DW, Halliday G, et al.: Diagnosis and management of dementia with Lewy bodies ; Fourth consensus report of the DLB Consortium. Neurology, 89(1) : 88-100(2017).
- 39) McKeith IG, Ferman TJ, Thomas AJ, Blanc F, et al. ; prodromal DLB Diagnostic Study Group : Research criteria for the diagnosis of prodromal dementia with Lewy bodies. Neurology, 94(17) : 743-755(2020).
- 40) McKhann GM, Knopman DS, Chertkow H, Hyman BT, et al.: The diagnosis of dementia due to Alzheimer's disease ; Recommendations from the National Institute on Aging-Alzheimer's Associa-tion workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement, 7(3) : 263-269(2011).
- 41) Minguez-Castellanos A, Chamorro CE, Escamilla-Sevilla F, Ortega-Moreno A, et al.: Do alpha-synu-clein aggregates in autonomic plexuses predate Lewy body disorders? ; A cohort study. Neurolo-gy, 68(23) : 2012-2018(2007).
- 42) Miyamoto M, Miyamoto T : Relationship of sub-stantia nigra hyperechogenicity to risk of Lewy body disease in idiopathic REM sleep behavior dis-order patients ; A longitudinal study. Sleep Med, 68 : 31-34(2020).
- 43) Mori F, Nishie M, Kakita A, Yoshimoto M, et al.: Relationship among alpha-synuclein accumula-tion, dopamine synthesis, and neurodegeneration in Parkinson disease substantia nigra. J Neuro-pathol Exp Neurol, 65(8) : 808-815(2006).
- 44) 両角佐織, 加藤重典, 安井敬三, 長谷川康博 : 著しい臥位高血圧, 血圧変動がposterior revers-ible encephalopathy syndrome(PRES)発症に関与したと考えられる進行期パーキンソン病の1例. 臨床神経学, 56(11) : 754-758(2016).
- 45) Moscovich M, Heinzel S, Postuma RB, Reilmann R, et al.: How specific are non-motor symptoms in the prodrome of Parkinson's disease compared to other movement disorders? Parkinsonism Relat Disord, 81 : 213-218(2020).
- 46) Nedelska Z, Schwarz CG, Lesnick TG, Boeve BF, et al.: Association of Longitudinal beta-Amyloid Accumulation Determined by Positron Emission Tomography With Clinical and Cognitive Decline in Adults With Probable Lewy Body Dementia. JAMA Netw Open, 2(12) : e1916439(2019).
- 47) Palermo G, Del Prete E, Bonuccelli U, Ceravolo R : Early autonomic and cognitive dysfunction in PD, DLB and MSA ; Blurring the boundaries between α-synucleinopathies. J Neurol, 267(12) : 3444-3456(2020).
- 48) Petrou M, Dwamena BA, Foerster BR, MacEach-ern MP, et al.: Amyloid deposition in Parkinson's disease and cognitive impairment ; A systematic review. Mov Disord, 30(7) : 928-935(2015).
- 49) Pistacchi M, Gioulis M, Contin F, Sanson F, et al.: Sleep disturbance and cognitive disorder ; Epide-miological analysis in a cohort of 263 patients. Neurol Sci, 35(12) : 1955-1962(2014).
- 50) Postuma RB, Gagnon JF, Vendette M, Fantini ML, et al.: Quantifying the risk of neurodegenerative disease in idiopathic REM sleep behavior disorder. Neurology, 72(15) : 1296-1300(2009).
- 51) Postuma RB, Gagnon JF, Vendette M, Montplaisir JY : Idiopathic REM sleep behavior disorder in the transition to degenerative disease. Mov Disord, 24(15) : 2225-2232(2009).
- 52) Postuma RB, Gagnon JF, Pelletier A, Montplaisir J : Prodromal autonomic symptoms and signs in Parkinson's disease and dementia with Lewy bod-ies. Mov Disord, 28(5) : 597-604(2013).
- 53) Postuma RB, Iranzo A, Hu M, Hogl B, et al.: Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder ; A multi-centre study. Brain, 142(3) : 744-759(2019).
- 54) Rongve A, Boeve BF, Aarsland D : Frequency and correlates of caregiver-reported sleep disturbanc-es in a sample of persons with early dementia. J Am Geriatr Soc, 58(3) : 480-486(2010).
- 55) Sarro L, Senjem ML, Lundt ES, Przybelski SA, et al.: Amyloid-beta deposition and regional grey matter atrophy rates in dementia with Lewy bod-ies. Brain, 139(Pt 10) : 2740-2750(2016).
- 56) Shannon KM, Keshavarzian A, Mutlu E, Dodiya HB, et al.: Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease. Mov Dis-ord, 27(6) : 709-715(2012).
- 57) Shibao CA, Biaggioni I : Management of Orthostat-ic Hypotension, Postprandial Hypotension, and Supine Hypertension. Semin Neurol, 40(5) : 515-522(2020).
- 58) Sperling RA, Aisen PS, Beckett LA, Bennett DA, et al.: Toward defining the preclinical stages of Alzheimer's disease ; Recommendations from the National Institute on Aging-Alzheimer's Associa-tion workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement, 7(3) : 280-292(2011).
- 59) Sunwoo MK, Hong JY, Choi J, Park HJ, et al.: α-Synuclein pathology is related to postoperative delirium in patients undergoing gastrectomy. Neu-rology, 80(9) : 810-813(2013).
- 60) Szatmari S Jr, Bereczki D, Fornadi K, Kalantar-Zadeh K, et al.: Association of Restless Legs Syn-drome With Incident Parkinson's Disease. Sleep, 40(2) : zsw065(2017).
- 61) Takahashi S, Mizukami K, Arai T, Ogawa R, et al.: Ventilatory Response to Hypercapnia Predicts De-mentia with Lewy Bodies Late-Onset Major De-pressive Disorder. J Alzheimers Dis, 50(3) : 751-758(2016).
- 62) Thaipisuttikul P, Lobach I, Zweig Y, Gurnani A, et al.: Capgras syndrome in Dementia with Lewy Bodies. Int Psychogeriatr, 25(5) : 843-849(2013).
- 63) Toledo JB, Gopal P, Raible K, Irwin D J, et al.: Pathological alpha-synuclein distribution in sub-jects with coincident Alzheimer's and Lewy body pathology. Acta Neuropathol, 131(3) : 393-409(2016).
- 64) Van Assche L, Van Aubel E, Van de Ven L, Bouckaert F, et al.: The Neuropsychological Profile and Phenomenology of Late Onset Psychosis ; A Cross-sectional Study on the Differential Diagno-sis of Very-Late-Onset Schizophrenia-Like Psy-chosis, Dementia with Lewy Bodies and Alzheimer's Type Dementia with Psychosis. Arch Clin Neuropsychol, 34(2) : 183-199(2019).
- 65) Vardy E, Holt R, Gerhard A, Richardson A, et al.: History of a suspected delirium is more common dementia with Lewy bodies than Alzheimer's disease ; A retrospective study. Int J Geriatr Psy-chiatry, 29(2) : 178-181(2014).
- 66) Watanabe-Nakayama T, Nawa M, Konno H. Kodera N, et al.: Self-and Cross-Seeding on α-Synuclein Fibril Growth Kinetics and Structure Observed by High-Speed Atomic Force Microscopy. ACS Nano, 14(8) : 9979-9989(2020).
- 67) Wong JC, Li Y, Schwarzschild MA, Ascherio A, et al.: Restless legs syndrome ; An early clinical feature of Parkinson disease in men. Sleep, 37(2) : 369-372(2014).
- 68) Yoon JH, Kim M, Moon SY, Yong SW, et al.: Olfacto-ry function and neuropsychological profile to dif-ferentiate dementia with Lewy bodies from Alzheimer's disease in patients with mild cognitive impairment ; A 5-year follow-up study. J Neurol Sci, 355(1-2) : 174-179(2015).