アブストラクト
Title | 病棟での便秘対応 高齢者 |
---|---|
Subtitle | 特集 薬の使い方が "超" わかる! 病棟での下痢・便秘対応 |
Authors | 竹田努, 永原章仁 |
Authors (kana) | |
Organization | 順天堂大学医学部附属順天堂医院消化器内科 |
Journal | 月刊薬事 |
Volume | 64 |
Number | 5 |
Page | 913-919 |
Year/Month | 2022 / 4 |
Article | 報告 |
Publisher | じほう |
Abstract | 「Key Point」 ●高齢者では便秘の有病率は上昇し, QOLを低下させる原因となる. ●便秘症状は排便回数だけではなく, 排便困難感, 残便感などにも着目する. ●基礎疾患の有無や薬剤性便秘など二次性の便秘も念頭に置き, 薬物療法の際には高齢者特有の副作用に注意する. ●高齢者の便秘では, 低栄養や筋力低下も関連しており, 多職種との連携が必要と考えられる. |
Practice | 薬学 |
Keywords |
- 全文ダウンロード: 従量制、基本料金制の方共に803円(税込) です。
参考文献
- 1) 日本消化器病学会関連研究会・他, 編:慢性便秘症診療ガイドライン2017. 南江堂, 2017
- 2) Suares NC, et al:Prevalence of, and risk factors for, chronic idiopathic constipation in the community:systematic review and meta-analysis. Am J Gastroenterol, 106:1582-1591, 2011
- 3) Wald A, et al:The burden of constipation on quality of life:results of a multinational survey. Aliment Pharmacol Ther, 26:227-236, 2007
- 4) Belsey J, et al:Systematic review:impact of constipation on quality of life in adults and children. Aliment Pharmacol Ther, 31:938-949, 2010
- 5) Tomita T, et al:Impact of chronic constipation on health-related quality of life and work productivity in Japan. J Gastroenterol Hepatol, 36:1529-1537, 2021
残りの28件を表示する
- 6) Honkura K, et al:Defecation frequency and cardiovascular disease mortality in Japan:The Ohsaki cohort study. Atherosclerosis, 246:251-256, 2016
- 7) Choung RS, et al:A prospective population-based nested case-control study. United European Gastroenterol J, 4:142-151, 2016
- 8) Chang JY, et al:Impact of functional gastrointestinal disorders on survival in the community. Am J Gastroenterol, 105:822-832, 2010
- 9) Sumida K, et al:Constipation and risk of death and cardiovascular events. Atherosclerosis, 281:114-120, 2019
- 10) Passmore AP:Economic aspects of pharmacotherapy for chronic constipation. Pharmacoeconomics, 7:14-24, 1995
- 11) 日本老年医学会・編:高齢者の安全な薬物療法ガイドライン2015. 日本老年医学会, 2015
- 12) Park SY, et al:Rectal gas volume measured by computerized tomography identifies evacuation disorders in patients with constipation. Clin Gastroenterol Hepatol, 15:543-552, 2017
- 13) Nullens S, et al:Regional colon transit in patients with dys-synergic defaecation or slow transit in patients with constipation. Gut, 61:1132-1139, 2012
- 14) Surrenti E, et al:Audit of constipation in a tertiary referral gastroenterology practice. Am J Gastroenterol, 90:1471-1475, 1995
- 15) Rao SS, et al:Investigation of the utility of colorectal function tests and Rome II criteria in dyssynergic defecation(Anismus). Neurogastroenterol Motil, 16:589-596, 2004
- 16) 竹田 努, 他:高齢者の慢性便秘症に関する直腸CT所見の関連因子の検討. 日本高齢消化器病学会誌, 24:100-107, 2022
- 17) Asaoka D, et al:The association between frailty and abdominal symptoms:A hospital-based cross-sectional study. Intern Med, 59:1677-1685, 2020
- 18) Asaoka D, et al:Association between the severity of constipation and sarcopenia in elderly adults:A single-center university hospital-based, cross-sectional study. Biomed Rep, 14:2, 2021
- 19) Rao SS, et al:Functional anorectal disorders. Gastroenterology, 2016
- 20) Kang SJ, et al:Medical management of constipation in elderly patients:systematic review. J Neurogastroenterol Motil, 27:495-512, 2021
- 21) Nakajima A, et al:Polyethylene glycol 3350 plus electrolytes for chronic constipation:a 2-week, randomized, double-blind, placebo-controlled study with a 52-week open-label extension. J Gastroenterol, 54:792-803, 2019
- 22) Fleming V, et al:A review of laxative therapies for treatment of chronic constipation in older adults. Am J Geriatr Pharmacother, 8:514-550, 2010
- 23) Ford AC, et al:Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation:systematic review and meta-analysis. Am J Gastroenterol, 109:1547-1561, 2014
- 24) Chmielewska A, et al:Systematic review of randomised controlled trials:probiotics for functional constipation. World J Gastroenterol, 16:69-75, 2010
- 25) Miller LE, et al:Probiotic supplementation decreases intestinal transit time:meta-analysis of randomized controlled trials. World J Gastroenterol, 19:4718-4725, 2013
- 26) Martinez-Martinez MI, et al:The effect of probiotics as a treatment for constipation in elderly people:A systematic review. Arch Gerontol Geriatr, 71:142-149, 2017
- 27) 竹田 努, 他:下痢と便秘の診断:問題点と対策 高齢者の慢性便秘症に対するプロバイオティクスの治療効果の検討. 日本消化管学会雑誌, 4:183, 2020
- 28) Odamaki T, et al:Age-related changes in gut microbiota composition from newborn to centenarian:a cross-sectional study. BMC Microbiol, 16:90, 2016
- 29) 竹田 努, 他:高齢者の慢性便秘症患者を対象とした便通異常改善効果に対するBifidobacterium longum BB536のランダム化二重盲検プラセボ対照並行群間比較試験. 日本消化管学会雑誌, 118:A689, 2021
- 30) Cherbut C, et al:Short-chain fatty acids modify colonic motility through nerves and polypeptide YY release in the rat. Am J Physiol, 275:1415-1422, 1998
- 31) Fukumoto S, et al:Short-chain fatty acids stimulate colonic transit via intraluminal 5-HT release in rats. Am J Physiol Regul Integr Comp Physiol, 284:1269-1276, 2003
- 32) Odamaki T, et al:Effect of probiotic yoghurt on animal-based diet-induced change in gut microbiota:an open, randomised, parallel-group study. Benef Microbes, 7:473-484, 2016
- 33) Yaeshima T, et al:Effect of yogurt containing bifidobacterium longum BB536 on the intestinal environment, fecal characteristics and defecation frequency. Bioscience and Microflora, 16:73-77, 1997