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Title 薬剤性の浮腫
Subtitle 特集 身体・検査所見を体液評価に活かす 浮腫と脱水の薬物治療 各論
Authors 植松卓也, 中塚真衣子
Authors (kana)
Organization 順天堂大学医学部附属順天堂医院薬剤部
Journal 月刊薬事
Volume 64
Number 13
Page 2701-2707
Year/Month 2022 / 10
Article 報告
Publisher じほう
Abstract [Key Point] ●浮腫の発生機序には, 多種多様な要因が関与するが, 多くの薬剤もその要因となりうる. ●薬剤性末梢性浮腫は, 4つの主要なメカニズムにより, 血管透過性浮腫, リンパ性浮腫, 血管拡張性浮腫, 腎性浮腫に分けられる. ●末梢性以外にも血管性浮腫, RS3PE症候群があり, 特に血管性浮腫は重篤化する場合もあるため注意が必要である. ●ハイリスク患者やリスク薬を服用する患者には, 薬剤性浮腫の発症予防も考慮しながら慎重な事前評価と継続的なモニタリングが重要である. ●薬剤性浮腫に対する治療の第一原則は, 被疑薬の中止または減量であるが, 類縁薬への変更も検討すべきである.
Practice 薬学
Keywords
  • 全文ダウンロード: 従量制、基本料金制の方共に803円(税込) です。

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