アブストラクト
| Title | β遮断薬 |
|---|---|
| Subtitle | 特集 Fantastic Four時代の心不全の治療戦略 心不全へのFantastic Fourの使い方 |
| Authors | 高麗謙吾 |
| Authors (kana) | |
| Organization | 小倉記念病院循環器内科 |
| Journal | 月刊薬事 |
| Volume | 65 |
| Number | 9 |
| Page | 1723-1727 |
| Year/Month | 2023 / 7 |
| Article | 報告 |
| Publisher | じほう |
| Abstract | [Key Points] ●β遮断薬は交感神経系を抑制し, 左室駆出率(LVEF)の低下した心不全の予後を改善する. ●LVEFの保たれた心不全への予後改善効果は示されていない. ●αβ遮断薬のカルベジロールとβ1選択性の高いビソプロロールを使い分ける. ●β遮断薬により心不全は急性増悪する可能性があり, 慎重に導入・増量する. ●心臓への副作用, 心臓以外の副作用も知っておく. |
| Practice | 薬学 |
| Keywords |
- 全文ダウンロード: 従量制、基本料金制の方共に803円(税込) です。
参考文献
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残りの5件を表示する
- 6) Palau P, et al: Effect of β-Blocker Withdrawal on Functional Capacity in Heart Failure and Preserved Ejection Fraction. J Am Coll Cardiol, 78:2042-2056, 2021
- 7) Dungen HD, et al; CIBIS-ELD investigators and Project Multicentre Trials in the Competence Network Heart Failure: Titration to target dose of bisoprolol vs. carvedilol in elderly patients with heart failure: the CIBIS-ELD trial. Eur J Heart Fail, 13:670-680, 2011
- 8) Tsutsui H, et al; CIBIS-J Investigators: Tolerability, Efficacy, and Safety of Bisoprolol vs. Carvedilol in Japanese Patients With Heart Failure and Reduced Ejection Fraction - The CIBIS-J Trial. Circ J, 83:1269-1277, 2019
- 9) McDonald M, et al: CCS/CHFS Heart Failure Guidelines Update: Defining a New Pharmacologic Standard of Care for Heart Failure With Reduced Ejection Fraction. Can J Cardiol, 37:531-546, 2021
- 10) Maddox TM, et al: 2021 Update to the 2017 ACC Expert Consensus Decision Pathway for Optimization of Heart Failure Treatment: Answers to 10 Pivotal Issues About Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol, 77:772-810, 2021

