アブストラクト
| Title | スポーツ障害に対するエコーを活用したPRP療法について |
|---|---|
| Subtitle | 特集 : 医師とセラピストをつなぐスポーツエコー活用 |
| Authors | 清水勇樹* |
| Authors (kana) | |
| Organization | *稲城平尾整形外科クリニック |
| Journal | MB Orthopaedics |
| Volume | 37 |
| Number | 5 |
| Page | 199-209 |
| Year/Month | 2024 / 5 |
| Article | 報告 |
| Publisher | 全日本病院出版会 |
| Abstract | 「Abstract」過去10年間, スポーツ医学におけるバイオロジクスの使用に急速な関心が高まり, 特に多血小板血漿(PRP)治療が注目されている. PRPに含まれる成長因子は, 治癒過程の各段階で細胞増殖, 血管新生を促進し, 効率的な修復を支援する. しかし, PRP療法の適用や効果は患者の状態や治療タイミングに依存し, すべての症例で等しく効果があるわけではない. エコーを使用することでPRPの正確な投与が可能となり, 治療後の経過観察やリハビリテーション計画の精度も向上する. 本稿では, スポーツ障害に対するPRP療法の臨床応用とその有効性について, エコーガイドを活用した治療方法を中心に紹介し, PRP療法の進展と臨床応用の可能性を探る. |
| Practice | 臨床医学：外科系 |
| Keywords | 多血小板血漿療法(PRP:platelet-rich plasma), エコー(ultrasound), スポーツ障害(sports injury) |
- 全文ダウンロード： 従量制、基本料金制の方共に968円(税込) です。
参考文献
- 1) Mlynarek RA, et al : Platelet-Rich Plasma(PRP) in Orthopedic Sports Medicine. Am J Orthop. 45 : 290-326, 2016.
- 2) Patrick AN, et al : An Update on Orthobiolog-ics : Cautious Optimism. Am J Sports Med. 52 : 242-257, 2024.
- 3) Galloway MT, et al : The Role of Mechanical Loading in Tendon Development, Maintenance, Injury, and Repair. J Bone Joint Surg Am. 95 : 1620-1628, 2013.
- 4) Zomer HD, et al : Skin wound healing in humans and mice : Challenges in translational research. J Dermatol Sci. 90 : 3-12, 2018.
- 5) 清水勇樹ほか : 膝関節内側側副靭帯損傷に対するPRP療法の一例 超音波画像所見の治癒経過. 日整超会誌. 32 : 118-123, 2021.
残りの20件を表示する
- 6) Dohan Ehrenfest DM, et al : Classification of platelet concentrates : from pure platelet-rich plasma(P-PRP) to leucocye-and platelet rich fibrin(L-PRF). Trends Biotechnol. 27 : 158-167, 2009.
- 7) Delong JM, et al : Platelet-rich plasma : the PAW classification system. Arthroscopy. 28 : 998-1009, 2012.
- 8) El-Sharkawy H, et al : Platelet-rich plasma : growth factors and pro- and anti-inflammatory properties. J Periodontol. 78 : 661-669, 2007.
- 9) Giusti I, et al : Platelet concentration in Plate-let-Rich Plasma affects tenocyte behavor in vitro. Biomed Res Int. 23 : 2014.
- 10) Engebretsen L, et al : IOC consensus paper on the use of platelet-rich plasma in sports medi-cine. Br J Sports Med. 44 : 1072-1081, 2010.
- 11) Hada S, et al : Conservative Treatment Using Platelet-Rich Plasma for Acute Anterior Cruci-ate Ligament Injuries in Highly Active Patients : A Retrospective Survey. Cureus. 16 : e53102, 2024.
- 12) Messina G, et al : Platelets-rich-plasma in man-agement of non operative post cruciate ligament injury. Eur J Transl Myol. 34(1) : 11535, 2023.
- 13) Greinacher A, et al : Thrombotic Thrombocy-topenia after ChAdOx1 nCov-19 Vaccination. N Engl J Med. 384 : 2092-2101, 2021.
- 14) Greinacher A, et al : Clinical features of hepa-rininduced thrombocytopenia including risk factors for thrombosis. A retrospective analy-sis of 408 patients. Thromb Haemost. 94 : 132-135, 2005.
- 15) Carofino B, et al : Corticosteroids and local anesthetics decrease positive effects of plate-let-rich plasma : an in vitro study on human tendon cells. Arthroscopy. 28 : 711-719, 2012.
- 16) Ludwig, HC, et al : Use of a Cyclooxygenase-2 Inhibitor Does Not Inhibit Platelet Activation or Growth Factor Release From Platelet-Rich Plasma. Am J Sports Med. 45 : 3351-3357, 2017.
- 17) Dregalla RC, et al : Effect of Local Anesthetics on Platelet Physiology and Function. J Orthop Res. 39 : 2744-2754, 2021.
- 18) Giuseppe L, et al : Influence of the needle bore size on platelet count and routine coagulation tes-ting. Blood Coagul Fibrinolysis. 17 : 557-561, 2006.
- 19) Upadhyay S, et al : Autologous platelet rich plasma versus corticosteroid injection for chronic plantar fasciitis : a prospective controlled ran-domized comparative clinical study. Int J Res Med Sci. 6 : 1594-1599, 2018.
- 20) Sheth U, et al : Does Platelet-Rich Plasma Lead to Earlier Return to Sport When Compared With Conservative Treatment in Acute Mus-cle Injuries? A Systematic Review and Meta-analysis. Arthroscopy. 34 : 281-288, 2018.
- 21) Sharaki F, et al : Determination of Effect of Platelet Rich Plasma Injection on Improving Pain and Function in Young Healthy Athletes with Isolated Grade 2 or 3 Knee Medial Collat-eral Ligament Sprains. Novelty in Biomedicine. 7 : 147-157, 2019.
- 22) Reurink G, et al : Magnetic resonance imaging in acute hamstring injury : can we provide a return to play prognosis?. Sports Med. 45 : 133-146, 2015.
- 23) Vetrano M, et al : Platelet-Rich Plasma Versus Focused Shock Waves in the Treatment of Jumper's Knee in Athletes. Am J Sports Med. 41 : 795-803, 2013.
- 24) Sanderson LM, et al : Effectiveness and safety of prolotherapy injections for management of lower limb tendinopathy and fasciopathy : a sys-tematic review. J Foot Ankle Res. 4 : 60, 2015.
- 25) Andriolo L, et al : Nonsurgical Treatments of Patellar Tendinopathy : Multiple Injections of Platelet-Rich Plasma Are a Suitable Option : A Systematic Review and Meta-analysis. Am J Sports Med. 47 : 1001-1018, 2019.
