~
検索条件をクリア

アブストラクト

Title 重症新生児慢性肺疾患の予防と管理
Subtitle 特集 知っておきたい周産期・新生児医療up to date 出生後
Authors 南谷曜平*, 難波文彦*
Authors (kana)
Organization *埼玉医科大学総合医療センター小児科
Journal 小児内科
Volume 55
Number 11
Page 1777-1783
Year/Month 2023 / 11
Article 報告
Publisher 東京医学社
Abstract 「Key Points」 (1) 超早産児の救命率向上に伴い, より重症なCLDが増加しており, 最重症例では長期の呼吸管理や肺高血圧症, 低酸素性呼吸不全を呈する. (2) サーファクタント補充療法やステロイド全身投与, カフェイン, 非侵襲的呼吸療法, HFOやNAVAなどCLD予防に一定のエビデンスがある既存の治療を組み合わせた管理が行われている. (3) CLDを根本的に解決するような新規治療の開発が今後の課題である.
Practice 臨床医学:内科系
Keywords
  • 全文ダウンロード: 従量制、基本料金制の方共に1,023円(税込) です。

参考文献

残りの21件を表示する
  • 6) Isayama T, Lee SK, Yang J, et al : Revisiting the definition of bronchopulmonary dysplasia : Effect of changing panoply of respiratory support for preterm neonates. JAMA Pediatr 171 : 271-279, 2017
  • 7) 厚生労働科学研究費補助金疾病・障害対策研究分野難治性疾患政策研究, 新生児慢性肺疾患の診断基準・病型分類の策定, 疾患レジストリの構築, および診療ガイドラインの作成に関する研究(研究代表者 難波文彦) https://mhlw-grants.niph.go.jp/project/163175
  • 8) Roberts D, Brown J, Medley N, et al : Antenatal corticosteroids for accelerating fetal lung matura-tion for women at risk of preterm birth. Cochrane Database Syst Rev 3 : CD0044542017, 2017
  • 9) Tanaka S, Tsumura K, Nakura Y, et al : New antibi-otic regimen for preterm premature rupture of membrane reduces the incidence of bronchopul-monary dysplasia. J Obstet Gynaecol Res 45 : 967-973, 2019
  • 10) Subramaniam P, Ho JJ, Davis PG : Prophylactic nasal continuous positive airway pressure for pre-venting morbidity and mortality in very preterm infants. Cochrane Database Syst Rev 2016 Jun 14 :(6): CD001243
  • 11) Rojas-Reyes MX, Morley CJ, Soll R : Prophylactic versus selective use of surfactant in preventing morbidity and mortality in preterm infants. Cochrane Database Syst Rev 2012 Mar14 :(3): CD000510
  • 12) Abiramalatha T, Ramaswamy VV, Bandyopadhyay T, et al : Interventions to prevent bronchopulmo-nary dysplasia in preterm neonates : An umbrella review of systematic reviews and meta-analyses. JAMA Pediatr 176 : 502-516, 2022
  • 13) Aldana-Aguirre JC, Pinto M, Featherstone RM, et al : Less invasive surfactant administration versus intubation for surfactant delivery in preterm infants with respiratory distress syndrome : a sys-tematic review and meta-analysis. Arch Dis Child Fetal Neonatal Ed 102 : F17-F23, 2017
  • 14) Ramaswamy VV, Bandyopadhyay T, Nanda D, et al : Efficacy of noninvasive respiratory support modes as postextubation respiratory support in preterm neonates : A systematic review and net-work meta-analysis. Pediatr Pulmonol 55 : 2924-2939, 2020
  • 15) Cools F, Offringa M, Askie LM : Elective high fre-quency oscillatory ventilation versus conven-tional ventilation for acute pulmonary dysfunc-tion in preterm infants. Cochrane Database Syst Rev 2015 Mar19 :(3): CD000104
  • 16) Goel D, Oei JL, Smyth J, et al : Diaphragm-trig-gered non-invasive respiratory support in preterm infants. Cochrane Database Syst Rev 2020 Mar17 ; 3(3): CD012935
  • 17) Klingenberg C, Wheeler KI, McCallion N, et al : Volume-targeted versus pressure-limited ventila-tion in neonates. Cochrane Database Syst Rev 2017 Oct17 ; 10(10): CD003666
  • 18) Kua KP, Lee SWH : Systematic review and meta-analysis of clinical outcomes of early caffeine therapy in preterm neonates. Br J Clin Pharmacol 83 : 180-191, 2017
  • 19) Doyle LW, Cheong JL, Hay S, et al : Early(<7days)systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants. Cochrane Database Syst Rev 2021 Oct21 ; 10(10): CD001146
  • 20) Doyle LW, Cheong JL, Hay S, et al : Late(>-7days)systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants. Cochrane Database Syst Rev 2021 Nov 11 ; 11(11): CD001145
  • 21) Nakamura T, Yonemoto N, Nakayama M, et al : Early inhaled steroid use in extremely low birth-weight infants : a randomised controlled trial. Arch Dis Child Fetal Neonatal Ed 101 : F552-F556, 2016
  • 22) Shah VS, Ohlsson A, Halliday HL, et al : Early administration of inhaled corticosteroids for pre-venting chronic lung disease in very low birth weight preterm neonates. Cochrane Database Syst Rev 2017 Jan4 ; 1(1): CD001969
  • 23) Barrington KJ, Finer N, Pennaforte T : Inhaled nitric oxide for respiratory failure in preterm infants. Cochrane Database Syst Rev 2017 Jan 3 ; 1(1): CD000509
  • 24) Askie LM, Darlow BA, Finer N, et al : Association between oxygen saturation targeting and death or disability in extremely preterm infants in the Neo-natal Oxygenation Prospective Meta-analysis Col-laboration. JAMA 319 : 2190-2201, 2018
  • 25) Ozawa Y, Miyake F, Isayama T : Efficacy and safety of permissive hypercapnia in preterm infants : A systematic review. Pediatr Pulmonol 57 : 2603-2613, 2022
  • 26) Watson J, McGuire W : Transpyloric versus gastric tube feeding for preterm infants. Cochrane Data-base Syst Rev 2013 Feb28 ; 2013(2): CD003487