アブストラクト
Japanese
| Title | 発熱と組織球主体の滲出性胸水で発症したTAFRO症候群の1例 |
|---|---|
| Subtitle | 症例 稀な疾患 |
| Authors | 窪田幸司a, 水野圭子b, 宮田真里奈a, 新村昌弘b, 濱崎哲郎a, 井上博雅b |
| Authors (kana) | |
| Organization | a公益社団法人鹿児島共済会南風病院呼吸器内科, b鹿児島大学大学院医歯学総合研究科呼吸器内科学 |
| Journal | 日本呼吸器学会誌 |
| Volume | 13 |
| Number | 1 |
| Page | 44-48 |
| Year/Month | 2024 / |
| Article | 報告 |
| Publisher | 日本呼吸器学会 |
| Abstract | 「要旨:」症例は66歳, 男性. 発熱と右胸水貯留の精査目的で, 当科に紹介入院となった. CRP上昇と血小板減少, プロカルシトニン陽性, 腎障害を認めた. 組織球主体の滲出性胸水であり, 播種性血管内凝固(disseminated intravascular coagulation:DIC)を合併し, 抗菌薬不応性であった. 頸部・腋窩・腹部傍大動脈リンパ節の軽度腫大, 腎障害, 胸腹水および全身浮腫の悪化があり, 骨髄生検で細網線維化と巨核球増多を認め, TAFRO症候群と診断した. 原因不明の胸膜炎を認める例では鑑別診断にTAFRO症候群を考慮する必要がある. |
| Practice | 臨床医学：内科系 |
| Keywords | TAFRO症候群, 滲出性胸水, プロカルシトニン, 播種性血管内凝固, TAFRO syndrome, Exudative pleural effusion, Procalcitonin, Disseminated intravascular coagulation (DIC) |
English
| Title | Thrombocytopenia, anasarca, myelofibrosis, renal dysfunction, and organomegaly syndrome accompanied by fever and histiocytic exudative pleural effusion : a case report |
|---|---|
| Subtitle | Case Reports Rare Diseases |
| Authors | Koji Kubota(a), Keiko Mizuno(b), Marina Miyata(a), Masahiro Shinmura(b), Tetsuro Hamasaki(a), Hiromasa Inoue(b) |
| Authors (kana) | |
| Organization | (a)Department of Respiratory Medicine, Nanpuh Hospital, (b)Department of Pulmonary Medicine, Graduate School of Medical & Dental Sciences, Kagoshima University |
| Journal | Annals of The Japanese Respiratory Society |
| Volume | 13 |
| Number | 1 |
| Page | 44-48 |
| Year/Month | 2024 / |
| Article | Report |
| Publisher | THE JAPANESE RESPIRATORY SOCIETY |
| Abstract | [Abstract] A 66-year-old man was referred to our hospital for evaluation of fever and right pleural effusion. Laboratory investigations showed elevated serum C-reactive protein levels, thrombocytopenia, procalcitonin positivity, and renal impairment. The patient had exudative pleural effusion, which predominantly showed histiocytes, complicated by disseminated intravascular coagulation, and remained refractory to antibiotics. We observed mild swelling of the cervical, axillary, and abdominal para-aortic lymph nodes, exacerbation of renal impairment, pleural effusion and ascites, and anasarca. Histopathological evaluation of a bone marrow biopsy specimen revealed reticulin fibrosis and megakaryocytosis, which led to the diagnosis of thrombocytopenia, anasarca, fever, myelofibrosis, renal insufficiency, and organomegaly (TAFRO) syndrome. TAFRO syndrome should be considered in the differential diagnosis of patients with pleuritis of unknown etiology. |
| Practice | Clinical internal medicine |
| Keywords | TAFRO syndrome, Exudative pleural effusion, Procalcitonin, Disseminated intravascular coagulation (DIC) |
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
参考文献
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残りの10件を表示する
- 6) 正木康史.胸腹水と血小板減少を伴った多中心性Castleman病の一亜型:新規疾患概念TAFRO症候群.血液内科 2014;68:97-102.
- 7) Iwaki N, et al. Atypical hyaline vascular-type Castleman's disease with thrombocytopenia, anasarca, fever, and systemic lymphadenopathy. J Clin Exp Hematop 2013; 53: 87-93.
- 8) 森澤紀彦,他.ステロイドおよびシクロスポリンが有用であったTAFRO 症候群の1例.日内会誌 2016;105:2432-40.
- 9) 小澤孝幸,他.Rituximabが著効したTAFRO症候群と思われるCastleman病類似症例.臨血 2014;55:350-5.
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