アブストラクト
Title | 最新の薬物療法時代におけるTACE |
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Subtitle | 今月のテーマ (総説) 肝細胞癌に対する最新の薬物療法時代における各種治療法の現況と展望 |
Authors | 上嶋一臣1) |
Authors (kana) | |
Organization | 1)近畿大学医学部消化器内科 |
Journal | 日本消化器病学会雑誌 |
Volume | 119 |
Number | 5 |
Page | 414-422 |
Year/Month | 2022 / 5 |
Article | 報告 |
Publisher | 日本消化器病学会 |
Abstract | 要旨: 肝細胞癌治療では, 全身薬物療法の発達により, 肝動脈化学塞栓療法(TACE)の適応条件が厳格になってきている. すなわち, 腫瘍量が少ないUp-to-7 INのような状況でのみ根治的TACEが施行される. さらには分子標的薬の併用でTACEの効果を最大化することが可能である. 一方, 腫瘍量が多いUp-to-7 OUTのような状況では, 壊死, 縮小効果の高いアテゾリズマブ・ベバシズマブ併用療法やレンバチニブなどを用いた全身薬物療法を行い, 奏効後にTACEを行う. Intermediate stageではTACEと薬物療法は相補的役割を果たしており, 腫瘍状態や肝予備能を考慮して治療方法を選択することが重要である. |
Practice | 臨床医学:内科系 |
Keywords | 全身薬物療法, TACE, Intermediate stage |
- 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
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