アブストラクト
| Title | 食物アレルギー診療ガイドライン2021 〜リスク因子と予防〜 |
|---|---|
| Subtitle | ガイドラインのワンポイント解説 |
| Authors | 大矢幸弘1)-3) |
| Authors (kana) | |
| Organization | 1)名古屋市立大学環境労働衛生学分野, 2)藤田医科大学総合アレルギー科, 3)国立成育医療研究センター |
| Journal | アレルギー |
| Volume | 73 |
| Number | 5 |
| Page | 389-394 |
| Year/Month | 2024 / |
| Article | 報告 |
| Publisher | 日本アレルギー学会 |
| Abstract | 「はじめに」21世紀は気管支喘息やアトピー性皮膚炎の有病率は増加が一段落した感があるが, 食物アレルギーに関しては, 先進国を中心にEpidemicの観を呈している. しかし, 乳幼児に多いIgE依存性の食物アレルギーに関しては, 二重抗原曝露仮説を実証する介入研究が相次いで発表され, 予防が現実的な視野に入ってきた. ガイドラインは網羅的な文献検索をベースにして作成されているため, 膨大な文献と様々なエビデンスレベルの情報が記載されているが, 本稿では, 高いエビデンス水準の臨床研究を中心に, 実臨床の現場で役立つトピックスに絞って解説する. 「食物アレルギーのリスク因子」「(1) アトピー性皮膚炎」食物アレルギー診療ガイドライン2021には, 「小児期の食物アレルギー発症リスクに影響する因子として, 家族歴, 特定の遺伝子, 皮膚バリア機能, 日光・ビタミンDなどが報告されているが, 中でもアトピー性皮膚炎が重要である」と記載されている. |
| Practice | 臨床医学：内科系 |
| Keywords | early intervention, eczema, food allergy, percutaneous sensitization |
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
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