アブストラクト
Title | 好酸球性消化管疾患 |
---|---|
Subtitle | 綜説 |
Authors | 山田佳之 |
Authors (kana) | |
Organization | 群馬県立小児医療センター |
Journal | アレルギー |
Volume | 69 |
Number | 4 |
Page | 260-266 |
Year/Month | 2020 / |
Article | 報告 |
Publisher | 日本アレルギー学会 |
Abstract | 「はじめに」好酸球性消化管疾患(eosinophilic gastrointestinal disorders [EGIDs])は好酸球の消化管局所への異常に高度な浸潤に伴い, 消化管の機能障害さらには器質的な変化をもたらし, それによって様々な症状を示す好酸球性炎症性疾患である. 様々な疾患に続発して発症することもあるが, 一次性EGIDsはアレルギー反応が主体と考えられている. また消化管の部位による違いでは通常は好酸球性食道炎(eosinophilic esophagitis [EoE])と好酸球性胃腸炎(eosinophilic gastroenteritis [EGE])に大別して考えられる. 小児から成人(高齢者)いずれの年齢でも発症し, 消化器科, アレルギー科だけでなく総合内科, 小児科, 時に外科系診療科でも遭遇する疾患である. 基本的には慢性疾患であるが, 急性期の症状のみで改善する場合もある. 重症例も存在し, 重症例については2015年から厚生労働省の指定難病となっている. |
Practice | 臨床医学:内科系 |
Keywords | eosinophilic colitis (EC), eosinophilic esophagitis (EoE), eosinophilic gastroenteritis (EGE), eosinophilic gastrointestinal disorders (EGIDs), eosinophils |
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