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Japanese

Title 錠剤嚥下障害の実態調査と服薬補助製品による服薬改善評価 - PILL-5アセスメントツールを用いて -
Subtitle 一般論文
Authors 大坪博子1, 倉田なおみ2,3, 大城真理奈4, 高橋伸幸5, 山口天士5, 田中広紀5, 楠裕美子6, 詫間章俊6, 三井奈緒7, 島本一志7, 伊藤綾花8, 越塚宏美8, 古屋宏章9, 大音師澄子10, 飯田純一11, 輿石徹12, 上田章人13, 萩田均司14, 坪内理恵子15, 宇都宮励子16, 森田俊博17
Authors (kana)
Organization 1昭和大学大学院薬学研究科社会薬学分野, 2昭和大学薬学部社会健康薬学講座社会薬学部門, 3臨床薬学講座臨床栄養代謝学部門, 4昭和大学病院, 5昭和大学病院附属東病院, 6昭和大学横浜市北部病院, 7昭和大学藤が丘リハビリテーション病院, 8昭和大学江東豊洲病院, 9昭和大学附属烏山病院, 10国家公務員共済組合連合会斗南病院, 11済生会横浜市南部病院, 12東京医科大学八王子医療センター, 13藤立病院, 14るりこし薬局, 15薬樹株式会社, 16大阪ファルマプラン, 17日野病院
Journal 医療薬学
Volume 50
Number 9
Page 473-485
Year/Month 2024 / 9
Article 報告
Publisher 日本医療薬学会
Abstract 「緒言」食物は咀嚼して唾液と混ぜることによって均一のペースト状の食塊をつくり嚥下する. 一方, 薬剤は錠剤やカプセル, 散剤などがあり, 大きさや形状も異なる. これらの薬剤は, 一般的に水で服用することが多いが, 薬剤の「固形物」と水などの「液体」を同時に嚥下する必要がある. 液体だけが先に流入するとむせや誤嚥を起こしたり, 薬が口腔内に残留することもあり, 薬剤のほうが食物に比べ嚥下の難易度は高いとされている. ドイツ一般開業医の調査では, 1錠以上を服薬している18〜80歳の受診患者1,051名のうち37.4%に服薬困難感を認めたとしている. 米国の医療機関を訪問した23〜77歳の99名を対象とした調査でも, 約50%が錠剤を飲み込むのが困難だったことがあると報告している. 小児に関しては, 錠剤の服用可能年齢は6歳と考えられているが, 実際には6歳の約半数は服用できていない.
Practice 薬学
Keywords pill dysphagia, potential pill dysphagia, PILL-5, deglutition aids, medication support

English

Title Investigation of Pill Dysphagia and Improvement Evaluation by Deglutition Aids - Using PILL-5 Assessment Tool -
Subtitle
Authors Hiroko Otsubo1, Naomi Kurata2,3, Marina Oshiro4, Nobuyuki Takahashi5, Takashi Yamaguchi5, Hironori Tanaka5, Yumiko Kusunoki6, Akitoshi Takuma6, Nao Mitsui7, Kazushi Shimamoto7, Ayaka Ito8, Hiromi Koshizuka8, Hiroaki Koya9, Sumiko Otoshi10, Junichi Iida11, Toru Koshiishi12, Akito Ueda13, Hitoshi Hagita14, Rieko Tsubouchi15, Reiko Utsunomiya16, Toshihiro Morita17
Authors (kana)
Organization 1Department of Social Pharmacy, Graduate School of Pharmacy, Showa University, 2Division of Social Pharmacy, Department of Healthcare and Regulatory Sciences, Division of Clinical Pharmacy School of Pharmacy, Showa University, 3Division of Clinical Pharmacy, Department of Clinical Nutrition and Metabolism, School of Pharmacy, Showa University, 4Showa University Hospital, 5Showa University East Hospital, 6Showa University Northern Yokohama Hospital, 7Showa University Fujigaoka Rehabilitation Hospital, 8Showa University Koto Toyosu Hospital, 9Showa University Karasuyama Hospital, 10Tonan Hospital, 11Saiseikai Yokohama-shi Nanbu Hospital, 12Tokyo Medical University Hachioji Medical Center, 13Fujitate Hospital, 14Rurikoshi Pharmacy, 15Yakuju Co, Ltd, 16Osaka Pharma Plan, 17Hino Hospital
Journal Japanese Journal of Pharmaceutical Health Care and Sciences
Volume 50
Number 9
Page 473-485
Year/Month 2024 / 9
Article Report
Publisher Japanese Society of Pharmaceutical Health Care and Sciences
Abstract Patients of different age groups have difficulty taking medications. Using the Japanese version of the PILL-5 assessment tool (PILL-5), we investigated patients with pill dysphagia and the degree of improvement with deglutition aids. Moreover, we investigated the factors, such as the position of the jaw, sex, and choking on water, associated with pill dysphagia. A total of 586 patients from 10 hospitals and 6 pharmacies aged 18 - 85 years, who were on regular self-administered medications and ate regularly, were included in the study. Out of 17 patients (2.9%) with pill dysphagia who had a total score >- 6, 6 showed considerable improvement in their PILL-5 total score and throat and chest tightness using deglutition aids. Notably, 81 patients (13.8%) with potential pill dysphagia had a PILL-5 score >- 2 for any one of the five items. Patients with pill dysphagia and potential pill dysphagia highly related with choking while taking pills (OR = 9.45, P < 0.001). Factors associated with patients having choking were < 65 years old (OR = 1.93, P = 0.031) and jaw position upward (OR = 2.31, P = 0.013). Patients with pill dysphagia, and those with potential pill dysphagia identified as choking on water while taking medicines and the position of their jaws. Therefore, supporting pill dysphagia at an early stage is necessary.
Practice Pharmaceutical sciences
Keywords pill dysphagia, potential pill dysphagia, PILL-5, deglutition aids, medication support
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