アブストラクト
Title | 中心静脈カテーテル関連血流感染症発症に関与する危険因子の探索 |
---|---|
Subtitle | 論文 原著論文 |
Authors | 星野祐太1, 渡邊卓嗣1, 西條文人2, 菅野和彦1 |
Authors (kana) | |
Organization | 1独立行政法人労働者健康安全機構東北労災病院薬剤部, 2外科 |
Journal | 日本病院薬剤師会雑誌 |
Volume | 57 |
Number | 5 |
Page | 548-552 |
Year/Month | 2021 / 5 |
Article | 原著 |
Publisher | 日本病院薬剤師会 |
Abstract | 中心静脈カテーテル関連血流感染症(central line-associated bloodstream infection:以下, CLABSI)の危険因子として世界的に複数の報告があるが, 日本人を対象とした報告は限られている. 本研究は, 中心静脈カテーテルを挿入した成人入院患者におけるCLABSI発症の危険因子を探索した. その結果, 体格指数および脂肪乳剤投与がCLABSI発症の独立した危険因子として同定された. さらに, CLABSI発症までの期間を比較したところ, CLABSI発症率は脂肪乳剤投与もしくは高カロリー輸液と脂肪乳剤の併用で経時的に高くなった. 本研究で同定された危険因子を有する患者に対し, 適切な栄養療法を実施し, 定期的な輸液ラインの交換とハブの消毒, 手指衛生の遵守を徹底・継続することで, CLABSI発症を予防できると考えられる. |
Practice | 薬学 |
Keywords | 中心静脈カテーテル関連血流感染症, 経静脈栄養, 脂肪乳剤, 危険因子 |
- 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
参考文献
- 1) V Stevens, K Geiger, C Concannon, RE Nelson, J Brown, G Dumyati: Inpatient costs, mortality and 30-day re-admission in patients with central-line-associated bloodstream infections, Clin Microbiol Infect, 20, O318-O324 (2014).
- 2) S Karagiannidou, T Zaoutis, N Maniadakis, V Papaevangelou, G Kourlaba: Attributable length of stay and cost for pediatric and neonatal central line-associated bloodstream infections in Greece, J Infect Public Health, 12, 372-379 (2019).
- 3) S Hosoglu, S Akalin, V Kidir, A Suner, H Kayabas, MF Geyik: Prospective surveillance study for risk factors of central venous catheter-related bloodstream infections, Am J Infect Control, 32, 131-134 (2004).
- 4) G Yilmaz, I Koksal, K Aydin, R Caylan, N Sucu, F Aksoy: Risk factors of catheter-related bloodstream infections in parenteral nutrition catheterization, J Parenter Enteral Nutr, 31, 284-287 (2006).
- 5) M Ishizuka, H Nagata, K Takagi, K Kubota: Femoral venous catheterization is a major risk factor for central venous catheter-related bloodstream infection, J Invest Surg, 22, 16-21 (2009).
残りの15件を表示する
- 6) D Bicudo, R Batista, GH Furtado, A Sola, EA Medeiros: Risk factors for central venous catheter-related bloodstream infection: a prospective multicenter study in Brazilian intensive care units, Braz J Infect Dis, 15, 328-331 (2011).
- 7) M Bekcibasi, S Dayan, E Aslan, MZ Kortak, S Hosoglu: Risk factors for central venous catheter-related bloodstream infections, Infez Med, 27, 258-265 (2019).
- 8) HS Chen, FD Wang, M Lin, YC Lin, LJ Huang, CY Liu: Risk factors for central venous catheter-related bloodstream infections in general surgery, J Microbiol Immunol Infect, 39, 231-236 (2006).
- 9) A Tarpatzi, A Avlamis, J Papaparaskevas, GL Daikos, I Stefanou, A Katsandri, A Vasilkopoulou, KS Chatzigeorgiou, GL Petrikkos: Incidence and risk factors for central vascular catheter-related bloodstream infections in a tertiary care hospital, New Microbiol, 35, 429-437 (2012).
- 10) Z Hajjej, M Nasri, W Sellami, H Gharsallah, I Labben, M Ferjani: Incidence, risk factors and microbiology of central vascular catheter-related bloodstream infection in an intensive care unit, J Infect Chemother, 20, 163-168 (2014).
- 11) G Fonseca, M Burgermaster, E Larson, DS Seres: The relationship between parenteral nutrition and central line-associated bloodstream infections: 2009-2014, J Parenter Enteral Nutr, 42, 171-175 (2018).
- 12) FD Battistella, JT Widergren, JT Anderson, JK Siepler, JC Weber, K MacColl: A prospective, randomized trial of intravenous fat emulsion administration in trauma victims requiring total parenteral nutrition, J Trauma, 43, 52-60 (1997).
- 13) MG Beghetto, J Victorino, L Teixeira, MJ de Avendo: Parenteral nutrition as a risk factor for central venous catheter-related infection, J Parenter Enteral Nutr, 29, 367-373 (2005).
- 14) A Toure, C Chambrier, P Vanhems, C Lombard-Bohas, JC Souquet, R Ecochard: Propensity score analysis confirms the independent effect of parenteral nutrition on the risk of central venous catheter-related bloodstream infection in oncological patients, Clin Nutr, 32, 1050-1054 (2013).
- 15) M Ishizuka, H Nagata, K Takagi, K Kubota: Total parenteral nutrition is a major risk factor for central venous catheter-related bloodstream infection in colorectal cancer patients receiving postoperative chemotherapy, Eur Surg Res, 41, 341-345 (2008).
- 16) T Nishida, H Sakakibara: Association between underweight and low lymphocyte count as an indicator of malnutrition in Japanese women, J Womens Health, 19, 1377-1383 (2010).
- 17) OM AL-Rawajfah, F Stetzer, JB Hewitt: Incidence of and Risk Factors for Nosocomial Bloodstream Infections in Adults in the United States, 2003, Infect Contorol Hosp Epidemiol, 30, 1036-1044 (2009).
- 18) T Kuwahara, S Kaneda, K Shimono, Y Inoue: Effects of lipid emulsion and multivitamins on the growth of microorganisms in peripheral parenteral nutrition solutions, Int J Med Sci, 10, 1079-1084 (2013).
- 19) A Pontes-Arruda, FX Liu, RS Turpin, CJ Mercaldi, M Hise, G Zaloga: Bloodstream infections in patients receiving manufactured parenteral nutrition with vs without lipids: is the use of lipids really deleterious?, J Parenter Enteral Nutr, 36, 421-430 (2012).
- 20) MJ Ocon Breton, AB Manas Martinez, AL Medrano Navarro, B Garcia Garcia, JA Gimeno Orna: Risk factors for catheter-related bloodstream infection in non-critical patients with total parenteral nutrition, Nutr Hosp, 28, 878-883 (2013).