アブストラクト
| Title | (1) バンコマイシン |
|---|---|
| Subtitle | 特集 抗菌薬TDM臨床実践ガイドライン2022のポイント |
| Authors | 松元一明 |
| Authors (kana) | |
| Organization | 慶應義塾大学薬学部薬効解析学講座 |
| Journal | 日本病院薬剤師会雑誌 |
| Volume | 58 |
| Number | 8 |
| Page | 889-892 |
| Year/Month | 2022 / 8 |
| Article | 報告 |
| Publisher | 日本病院薬剤師会 |
| Abstract | 「はじめに」抗菌薬は薬物動態学/薬力学 (pharmacokinetics/pharmacodynamics : 以下, PK/PD) に基づいて使用することが推奨されている. PK/PD解析により, バンコマイシン (vancomycin : 以下, VCM) の有効性および安全性と最も相関する指標は, 血中濃度時間曲線下面積 (area under the blood concentration-time curve : 以下, AUC) である. これまでAUCの代替指標としてトラフ値が用いられてきたが, 近年の研究により, トラフ値が代替指標とならないケースや, 解析ソフトを用いてAUCを簡便に算出できるようになったため, 今回のガイドラインでは, より安全にVCMを使用することを目的にAUC評価が推奨された. この点が今回のガイドライン改訂の最大のポイントである. |
| Practice | 薬学 |
| Keywords |
- 全文ダウンロード： 従量制、基本料金制の方共に770円(税込) です。
参考文献
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残りの20件を表示する
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