アブストラクト
Japanese
Title | 小児の膠原病の皮疹 |
---|---|
Subtitle | 総説 |
Authors | 山本俊幸1) |
Authors (kana) | |
Organization | 1)福島県立医科大学医学部皮膚科 |
Journal | 日本皮膚免疫アレルギー学会雑誌 |
Volume | 3 |
Number | 3 |
Page | 381-390 |
Year/Month | 2020 / 10 |
Article | 報告 |
Publisher | 日本皮膚免疫アレルギー学会 |
Abstract | 「要旨」膠原病は, 遺伝的素因に後天的なトリガー(紫外線, 寒冷刺激, 仕事で扱う有機溶媒などの環境要因や感染症等)が加わって発症する. 女性が多いので, ホルモンの影響も大きいと考えられている. それに対し, 小児発症例は遺伝的な影響がより強いものと思われる. 本稿では, 実際の皮膚科診療で診る機会の比較的少ない, 小児の膠原病を取り上げ, その皮膚症状について概説した. |
Practice | 臨床医学:内科系 |
Keywords | エリテマトーデス, 強皮症, 皮膚筋炎, シェーグレン症候群, ベーチェット病, サルコイドーシス, erythematosus, scleroderma, dermatomyositis, Sjogren's syndrome, Behcet's disease, sarcoidosis |
English
Title | Skin Manifestation of Pediatric Patients with Connective Tissue Diseases |
---|---|
Subtitle | Review |
Authors | Toshiyuki YAMAMOTO1) |
Authors (kana) | |
Organization | 1)Department of Dermatology, Fukushima Medical University |
Journal | Nihon Hifu Meneki Arerugi Gakkai Zasshi |
Volume | 3 |
Number | 3 |
Page | 381-390 |
Year/Month | 2020 / 10 |
Article | Report |
Publisher | The Japanese Society for Cutaneous Immunology and Allergy |
Abstract | Connective tissue diseases are common in adult females, but pediatric cases are rare. Dermatologists have few chances to treat pediatric patients; however, cutaneous manifestations are important as a clue for diagnosis, especially in the early or preliminary stages of pediatric connective tissue diseases. Juvenile cases of systemic lupus erythematosus, systemic sclerosis, dermatomyositis, Sjogren's syndrome, Behcet's disease, and sarcoidosis were reviewed, and an overview of current knowledge is provided. |
Practice | Clinical internal medicine |
Keywords | erythematosus, scleroderma, dermatomyositis, Sjogren's syndrome, Behcet's disease, sarcoidosis |
- 全文ダウンロード: 従量制、基本料金制の方共に770円(税込) です。
参考文献
- 1) Tarvin SE, O'Neil KM : Systemic lupus erythema-tosus, Sjogren syndrome, and mixed connective tissue disease in children and adolescents, Pediatr Clin N Am, 65 : 711-737, 2018
- 2) Chiewchengchol D, Murphy R, Edwards SW, et al : Mucocutaneous manifestations in juvenile-onset systemic lupus erythematosus : a review of litera-ture, Pediatr Rheumatol, 13 : 1, 2015
- 3) Watson L, Leone V, Pilkington C, et al : Disease activity, severity, and damage in the UK juve-nile-onset systemic lupus erythematosus cohort, Arthritis Rheum 64 : 2356-2365, 2012
- 4) Hedrich CM, Smith EMD, Beresford MW : Juve-nile-onset systemic lupus erythematosus(jSLE) : pathophysiological concepts and treatment options, Best Pract Res Clin Rheumatol, 31 : 488-504, 2017
- 5) Smith EMD, Lythgoe H, Midgley A, et al : Juvenile-onset systemic lupus erythematosus : update on clinical presentation, pathophysiology and treat-ment options, Clin Immunol, 209 : 108274, 2019
残りの39件を表示する
- 6) Volpi S, Picco P, Caorsi R, et al : Type I interferono-pathies in pediatric rheumatology, Pediatr Rheumatol, 14 : 35, 2016
- 7) Lo MS : Insights gained from the study of pediatric systemic lupus erythematosus, Front Immunol, 9 : 1278, 2018
- 8) Bundhun PK, Kumari A, Huang F : Differences in clinical features observed between childhood-onset versus adult-onset systemic lupus erythematosus : a systematic review and meta-analysis, Medicine, 96 : 37(e8086), 2017
- 9) Hoffman IEA, Lauwerys BR, de Keyser F, et al : Juvenile-onset systemic lupus erythematosus : different clinical and serological pattern than adult-onset systemic lupus erythematosus, Ann Rheum Dis, 68 : 412-415, 2009
- 10) Huttenlocher A, Smith JA : Neutrophils in pediat-ric autoimmune disease, Curr Opin Rheumatol, 27 : 500-504, 2015
- 11) Rahman S, Sagar D, Hanna RN, et al : Low-density granulocytes activate T cells and demonstrate a non-suppressive role in systemic lupus erythema-tosus, Ann Rheum Dis, 78 : 957-966, 2019
- 12) Giaglis S, Hahn S, Hasler P : "The NET Outcome" : are neutrophil extracellular traps of any relevance to the pathophysiology of autoimmune disorders in childhood? Front Pediatr, 4 : 97, 2016
- 13) Smith EMD, Lythgoe H, Hedrich CM : Vasculitis in juvenile-onset systemic lupus erythematosus, Front Pediatr, 8 : 149, 2019
- 14) Van Gysel D, de Waard-van der Spek FB, Oranje AP : Childhood discoid lupus erythematosus : re-port of five new cases and review of the literature, J Eur Acad Dermatol Venereol, 16 : 143-147, 2002
- 15) George PM, Tunnessen WW : Childhood discoid lupus erythematosus, Arch Dermatol, 129 : 613, 1993
- 16) Alkharafi NN, Alsaeid K, AlSumait A, et al : Cutaneous lupus erythematosus in children : ex-perience from a tertiary care pediatric dermatolo-gy clinic, Pediatr Dermatol, 33 : 200, 2016
- 17) Arkin LM, Ansell L, Rademaker A, et al : The natural history of pediatric-onset discoid lupus erythematosus, J Am Acad Dermatol, 72 : 628-633, 2015
- 18) Wimmershoff MB, Hohenleutner U, Landthaler M : Discoid lupus erythematosus and lupus profundus in childhood : a report of two cases, Pediatr Dermatol, 20 : 140, 2003
- 19) Weingartner JS, Zedek DC, Burkhart CN, et al : Lupus erythematosus panniculitis in children : report of three cases and review of previously reported cases, Pediatr Dermatol, 29 : 169, 2012
- 20) Chottawornsak N, Rodsaward P, Suwannachote S, et al : Skin signs in juvenile-and adult-onset systemic lupus erythematosus : clues to different systemic involvement, Lupus, 27 : 2069-2075, 2018
- 21) Park HS, Choi JW, Kim BK, et al : Lupus erythema-tosus panniculitis : clinicopathological, immunophe-notypic, and molecular studies, Am J Dermato-pathol, 32 : 24-30, 2010
- 22) Berry T, Walsh E, Berry R, et al : Subacute cutaneous lupus erythematosus presenting in childhood : a case report and review of the litera-ture, Pediatr Dermatol, 31 : 368-372, 2014
- 23) Lee LA : Neonatal lupus : clinical features and management, Paediatr Drugs, 6 : 71-78, 2004
- 24) Miyagawa S : Neonatal lupus erythematosus : a review of the racial differences and similarities in clinical, serological and immunogenetic features of Japanese versus Caucasian patients, J Dermatol, 32 : 514-522, 2005
- 25) Wienke J, Deakin CT, Wedderburn LR, et al : Systemic and tissue inflammation in juvenile dermatomyositis : from pathogenesis to the quest for monitoring tools, Front Immunol, 9 : 2951, 2018
- 26) Saini I, Kalaivani M, Kabra SK : Calcinosis in juvenile dermatomyositis : frequency, risk factors and outcome, Rheumatol Int, 36 : 961-965, 2016
- 27) Tansley S, McHugh NJ, Wedderburn LR : Adult and juvenile dermatomyositis : are the distinct clinical features explained by our current under-standing of serological subgroups and pathogenic mechanisms? Arthritis Res Ther, 15 : 211, 2013
- 28) Hsu V, Varga J, Schlesinger N : Calcinosis in scleroderma made crystal clear, Curr Opin Rheumatol, 31 : 589, 2019
- 29) Salman A, Kasapcopur O, Ergun T, et al : Panniculi-tis in juvenile dermatomyositis : report of a case and review of the published work, J Dermatol, 43 : 951-953, 2016
- 30) Happle R : Superimposed segmental dermatomy-ositis is a juvenile disorder, Eur J Dermatol, 24 : 291-292, 2014
- 31) Stevens AM, Torok KS, Li SC, et al : Immuno-pathogenesis of juvenile systemic sclerosis, Front Immunol, 10 : 1352, 2019
- 32) Foeldvari I : Systemic sclerosis in childhood, Rheumatology, 45 : iii28-iii29, 2006
- 33) Aoyama K, Nagai Y, Endo Y, et al : Juvenile systemic sclerosis : report of three cases and review of Japanese publish work, J Dermatol, 34 : 658-661, 2007
- 34) Foeldvari I : Update on pediatric systemic scler-osis : similarities and differences from adult disease, Curr Opin Rheumatol, 20 : 608-612, 2008
- 35) Kunzler E, Florez-Pollack S, Teske N, et al : Linear morphea : clinical characteristics, disease course, and treatment of the morphea in adults and children cohort, J Am Acad Dermatol, 80 : 1664-1670, 2019
- 36) Christen-Zaech S, Hakim MD, Afsar FS, et al : Pediatric morphea(localized scleroderma) : re-view of 136 patients, J Am Acad Dermatol, 59 : 385-396, 2008
- 37) Matsumoto M, Yamamoto T : Pediatric general-ized morphea that developed at a BCG vaccination site, Actas Dermosifiliogr, 106 : 150-152, 2015
- 38) Sibbitt W, Williams Jr. RC : Cutaneous manifesta-tions of rheumatoid arthritis, Int J Dermatol, 21 : 563-572, 1982
- 39) Houghton K, Malleson P, Cabral D, et al : Primary Sjogren's syndrome in children and adolescents : are proposed diagnostic criteria applicable? J Rheumatol, 32 : 2225, 2005
- 40) Kone-Paut I : Behcet's disease in children, an overview, Pediatr Rheumatol, 14 : 10, 2016
- 41) Kone-Paut I, Shahram F, Darce-Bello M, et al : Consensus classification criteria for paediatric Behcet's disease from a prospective observational cohort : PEDBD, Ann Rheum Dis, 75 : 958-964, 2016
- 42) Yildiz M, Koker O, Adrovic A, et al : Pediatric Behcet's disease : clinical aspects and current concepts, Eur J Rheumatol, 7(Suppl 1) : S38-S47, 2020
- 43) Ozen S, Eroglu FK : Pediatric-onset Behcet dis-ease, Curr Opin Rheumatol, 25 : 636-642, 2013
- 44) Reiff A, Weinberg KI, Triche T, et al : T lympho-cyte abnormalities in juvenile systemic sclerosis patients. Clin Immunol, 149 : 146-155, 2013