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Title 新型コロナウイルス感染症と川崎病
Subtitle 特集 COVID-19 第2波に備えてできること
Authors 森雅亮
Authors (kana)
Organization 東京医科歯科大学大学院医歯学総合研究科 生涯免疫難病学講座
Journal 臨床とウイルス
Volume 48
Number 4
Page 269-274
Year/Month 2020 / 10
Article 報告
Publisher 日本臨床ウイルス学会
Abstract 〔論文要旨〕最近の研究において, COVID-19と診断された一部の小児が, 発熱, 両側結膜充血, 口唇・口腔の変化, 頸部リンパ節腫脹, 四肢の変化, および川崎病 (Kawasaki disease, 以下KD) またはhyperinflammatory syndromeの発疹に類似した多形性発疹などの症状を発症したことが示された. このことから, COVID-19とKDとの関連性が世界的に注目を浴びるようになった. そこで, この論文ではこれまで報告されたCOVID-19感染症とKDについての論文から, 検査値や臨床的特徴についてまとめてみた. これらの欧米での報告は多く存在する一方で, 日本をはじめとした東アジア諸国では同様な報告はほとんどみられていない. わが国における実態はまだ観察中であるが, 川崎病学会からの提言から鑑みると, 両者の間には大きさ差異があるように思われた.
Practice 臨床医学：内科系
Keywords COVID-19, 血球貪食症候群, 川崎病, 小児多系統炎症性症候群 (MIS-C), SARS-CoV-2関連小児炎症性多系統症候群 (PIMS-TS), hyperinflammatory syndrome, Kawasaki disease, multi-system inflammatory syndrome in children (MIS-C), pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS)

English

Title COVID-19 and Kawasaki disease
Subtitle
Authors Masaaki MORI
Authors (kana)
Organization Graduate School of Medical and Dental Sciences, Endowed Departments, Department of Lifetime Clinical Immunology
Journal Clinical Virology
Volume 48
Number 4
Page 269-274
Year/Month 2020 / 10
Article Report
Publisher Japanese Society of Clinical Virology
Abstract Children diagnosed with COVID-19 were recently reported to have fever, bilateral conjunctival hyperemia, lip/oral changes, cervical lymphadenopathy, limb changes and polymorphic rash such as Kawasaki disease (KD) or hyperinflammatory syndrome. As a result, the relationship between COVID-19 and KD has attracted attention worldwide. Therefore, in this article, I summarized the laboratory values and clinical features from reports on COVID-19 infection and KD reported to date. Although there are many reports from Europe and the United States, there are few similar reports from East Asian countries such as Japan. The actual situation in Japan is still under observation, but considering the proposal from the Japanese Society of Kawasaki Disease, there may be a large difference between East Asian and Western countries.
Practice Clinical internal medicine
Keywords COVID-19, hyperinflammatory syndrome, Kawasaki disease, multi-system inflammatory syndrome in children (MIS-C), pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS)
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