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Title	新生児・乳児の嚢胞性肺疾患
Subtitle	レビュー
Authors	臼井規朗
Authors (kana)
Organization	大阪母子医療センター小児外科
Journal	日本周産期・新生児医学会雑誌
Volume	57
Number	3
Page	409-421
Year/Month	2021 / 12
Article	報告
Publisher	日本周産期・新生児医学会
Abstract	「概要」小児の嚢胞性肺疾患の分類には, いまだ確立されたものがないが, 本稿の総論では, 冒頭で最近の新しい考え方に基づいたわが国の小児嚢胞性肺疾患の分類を詳述する. 近年は多数の先天性嚢胞性肺疾患が出生前診断されるようになったことから, 周産期・新生児領域に関連した医療者の理解を深めるため, 先天性嚢胞性肺疾患の出生前診断や重症度予測についても解説を加える. 出生後, 新生児や乳児に認められる嚢胞性肺疾患については, 画像診断における特徴と, 病態や臨床症状に加え, 手術も含めた治療の要点について述べる. また, 嚢胞性肺疾患に対する肺切除後には, いくつかの合併症が懸念されるため, 晩期合併症や呼吸機能, 悪性腫瘍との関連性について解説する. 各論では, 新生児や乳児に比較的多く認められる嚢胞性肺疾患として, 先天性肺気道奇形(CPAM), 気管支閉鎖症, 肺分画症, 気管支原性嚢胞, 肺炎後肺嚢胞, 遷延性間質性肺気腫, 気腫性嚢胞・胸膜下嚢胞, 胸膜肺芽腫を取り上げて概説する. また, 嚢胞性肺疾患との鑑別を要する小児のびまん性肺嚢胞についても言及する.
Practice	臨床医学：外科系
Keywords	先天性嚢胞性肺疾患, 先天性肺気道奇形, CPAM, 気管支閉鎖症, 肺分画症

English

Title	Cystic lung diseases in neonates and infants
Subtitle
Authors	Noriaki Usui
Authors (kana)
Organization	Department of Pediatric Surgery, Osaka Women's and Children's Hospital
Journal	Journal of Japan Society of Perinatal and Neonatal Medicine
Volume	57
Number	3
Page	409-421
Year/Month	2021 / 12
Article	Report
Publisher	Japan Society of Perinatal and Neonatal Medicine
Abstract	Although there is still no established classification of cystic lung disease in children, a novel classification of pediatric cystic lung disease in Japan has recently been identified. Since many cases of congenital cystic lung diseases have been diagnosed before birth in recent years, prenatal diagnosis and prediction of severity for congenital cystic lung disease will be added for a better understanding of the fellow members of the society of perinatal and neonatal medicine. Regarding cystic lung disease observed in infants after birth, features based on diagnostic imaging and the essential points of the treatment, including surgery, are described. In addition, pathology and clinical symptoms are defined. We also discuss late complications after lung resection and their associations with respiratory function and malignancy for cystic lung diseases. In cystic lung diseases, which are relatively common in neonates and infants, congenital pulmonary airway malformation, bronchial atresia, pulmonary sequestration, bronchogenic cyst, pneumatocele, persistent pulmonary interstitial emphysema, bullla and bleb, and pleuropulmonary blastoma are further explained. We also discuss diffuse pulmonary cystic diseases in children, which should be differentiated from cystic lung disease.
Practice	Clinical surgery
Keywords	CPAM

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参考文献

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