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Japanese

Title 『血液透析患者の運動耐容能と透析中のΔBlood Volumeの関係』
Subtitle 原著
Authors 矢部広樹*1,2, 河野健一*3, 若山功治*4, 村上淳*5, 花房規男*6, 新田孝作*7, 土谷健*6
Authors (kana)
Organization *1聖隷クリストファー大学 リハビリテーション学部 理学療法学科, *2医療法人偕行会 名古屋共立病院 リハビリテーション課, *3国際医療福祉大学 成田保健医療学部 理学療法学科, *4わかやま透析クリニック中野南台, *5東京女子医科大学病院 臨床工学部, *6血液浄化療法科, *7第四内科
Journal 日本血液浄化技術学会雑誌
Volume 28
Number 1
Page 2-9
Year/Month 2020 / 9
Article 原著
Publisher 日本血液浄化技術学会
Abstract <要旨> 【目的】本研究は, 血液透析患者の運動耐容能と透析中のΔBVの推移の関連を検討した. 【方法】血液透析患者20名を対象に心肺運動負荷試験を実施し, 運動耐容能の指標である嫌気性代謝閾値 (VO2AT) と最高酸素摂取量 (VO2peak) を測定した. また心肺運動負荷試験実施の翌週以降の透析で, 透析開始から終了までのΔBVの回帰式の傾きを算出した. そして各運動耐容能の指標とΔBVの傾きとの関連を検討した. 【結果】VO2AT (r=0.44) とVO2peak (r=0.54) は, どちらも透析中のΔBVの傾きと有意な相関を認めた (p<0.05) . また総除水率を制御変数とした偏相関係数を検討した結果, ΔBVとVO2peak (r=0.47) との間に有意な関連を認めた (p<0.05) . 【考察】運動耐容能が高い対象ほど, 透析中のΔBV低下が小さかった. 運動耐容能と透析中のΔBVとの間に何らかの関係性が示唆されたが, メカニズムは不明であり, 今後の検討が必要である.
Practice 医療技術
Keywords 運動耐容能, ΔBV, 血液透析, Exercise tolerance, Δ Blood volume, hemodialysis

English

Title The association between exercise tolerance and Δ Blood volume in hemodialysis patients.
Subtitle
Authors Hiroki Yabe*1,2, Kenichi Kono*3, Koji Wakayama*4, Jun Murakami*5, Norio Hanafusa*6, Kosaku Nitta*7, Ken tsuchiya*6
Authors (kana)
Organization *1Department of Physical Therapy, School of Rehabilitation Sciences, Seirei Christopher University, *2Department of Rehabilitation, Nagoya Kyoritsu Hospital, *3Department of Physical Therapy, School of Health Sciences at Narita, International University of Health and Welfare., *4Wakayama Dialysis Clinic, *5Department of Blood Purification Therapy, Tokyo Women's Medical University., *6Department of Blood Purification, Kidney Center, Tokyo Women's Medical University, *7Department of Medicine, Kidney Center, Tokyo Women's Medical University
Journal Journal of Japanese Society for Technology of Blood purification
Volume 28
Number 1
Page 2-9
Year/Month 2020 / 9
Article Original article
Publisher Japanese Society for Technology of Blood purification
Abstract <Summary> [Objectives] The purpose of this study is to investigate the relationship between the exercise tolerance measured by cardiopulmonary exercise testing (CPX) and the Δ Blood volume (ΔBV) during dialysis in patients with hemodialysis. [Methods] Anaerobic threshold (VO2AT) and peak oxygen uptake (VO2peak) that are indicators of exercise tolerance were measured by CPX from 20 hemodialysis patients. The slope of the regression equation of ΔBV from the start to the end of dialysis was calculated in hemodialysis session after the next week of CPX. In addition, the relationship between the slope of the regression equation of ΔBV and VO2at or VO2peak was examined by Pearson's correlation coefficient. [Results] Both VO2AT (r = 0.44) and VO2peak (r = 0.54) were significantly correlated with the slope of ΔBV (p <0.05). Result of partial correlation coefficient that fluid removal rate is control variable, VO2peak (r = 0.54) had significant correlation with the slope of ΔBV (p <0.05). [Discussion] The subjects with higher exercise tolerance had lower ΔBV reduction during dialysis. Because of VO2peak reflects the blood supply capacity, the higher the exercise tolerance of the subject, the more the circulating blood volume to the peripheral tissue was retained, and ΔBV reduction might be prevented.
Practice Medical technology
Keywords Exercise tolerance, Δ Blood volume, hemodialysis
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