アブストラクト
Japanese
| Title | 第5章 病態評価のための検査法 |
|---|---|
| Subtitle | ガイドライン解説 : 小児気管支喘息治療・管理ガイドライン2020 |
| Authors | 平井康太1)2), 望月博之1) |
| Authors (kana) | |
| Organization | 1)東海大学医学部総合診療学系小児科学, 2)東海大学医学部付属八王子病院小児科 |
| Journal | 日本小児アレルギー学会誌 |
| Volume | 35 |
| Number | 3 |
| Page | 256-261 |
| Year/Month | 2021 / |
| Article | 報告 |
| Publisher | 日本小児アレルギー学会 |
| Abstract | 抄録: 小児気管支喘息治療・管理ガイドライン(Japanese Pediatric Guideline for the Treatment and Management of Asthma: JPGL)2017に引き続き, 「病態評価のための検査法」として, 小児気管支喘息の診断と治療に必要な客観的な検査について説明している. 喘息の基本的な免疫異常であるTh2型反応の評価, すなわち, 血清総IgE値や末梢血好酸球数, アレルゲン特異的IgE抗体やプリックテストから, 喘息の診断や重症度の評価, 治療効果の判定に重要である呼吸機能検査[スパイロメトリー, 強制オシレーション法(forced oscillation technique: FOT), 気道過敏性検査を含む]や呼気NO測定について解説した. これらの検査の中で, スパイロメトリーが最も重要であるため, 原理から測定結果の解釈, 小児患者での実施上の留意点について解説を加えた. さらに, いくつかの新しい評価法についての解説も行っている. |
| Practice | 臨床医学：内科系 |
| Keywords | 気道過敏性試験, 呼気中一酸化窒素 (FeNO), 気道可逆性試験, スパイロメトリー, airway hyperresponsiveness testing, fractional exhaled nitric oxide (FeNO), reversibility testing, spirometry |
English
| Title | Commentary on Japanese Pediatric Guideline for the Treatment and Management of Asthma 2020 Chapter 5 Objective evaluation of asthma : lung function and biomarkers |
|---|---|
| Subtitle | |
| Authors | Kota Hirai1)2), Hiroyuki Mochizuki1) |
| Authors (kana) | |
| Organization | 1)Department of Pediatrics, Tokai University School of Medicine, 2)Department of Pediatrics, Tokai University Hachioji Hospital |
| Journal | The Japanese Journal of Pediatric Allergy and Clinical Immunology |
| Volume | 35 |
| Number | 3 |
| Page | 256-261 |
| Year/Month | 2021 / |
| Article | Report |
| Publisher | Japanese Society of Pediatric Allergy and Clinical Immunology |
| Abstract | Summary: Following the Japanese Pediatric Guideline for the Treatment and Management of Asthma: JPGL 2017, the objective tests required for the diagnosis and treatment of pediatric bronchial asthma are described. The evaluation of the Th2-type response, which is the basic immune abnormality in asthma, is discussed, including serum total IgE level, peripheral blood eosinophil count, allergen-specific IgE antibodies and skin prick test. Practically, evaluation of respiratory function [including spirometry, forced oscillation technique (FOT) and bronchial hyperresponsiveness test] and fractional exhaled nitric oxide (FeNO) measurement, which are important for diagnosis of asthma, evaluation of severity and therapeutic effect, are described in detail. Since spirometry is the most important test, the principle of measurement, the interpretation of results and the points to be noted in the pediatric patients are explained. Other new techniques for evaluation of airway condition and airway inflammation are also introduced. |
| Practice | Clinical internal medicine |
| Keywords | airway hyperresponsiveness testing, fractional exhaled nitric oxide (FeNO), reversibility testing, spirometry |
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